Isofan insulin: umarnin don amfani da farashin miyagun ƙwayoyi
Nau'in 2 na ciwon sukari mellitus, mataki na tsayayya da maganganu na maganganu na rashin ƙarfi, wani yanki na juriya ga magungunan baka na baki (haɗuwa da cuta), cututtukan da ke tsakanin mutum, ayyukan tiyata (ƙwayar cuta-da haɗuwa), ciwon sukari na mellitus yayin daukar ciki (tare da maganin rashin abinci).
Yadda ake amfani: sashi da hanya na jiyya
P / C, sau 1-2 a rana, mintuna 30-45 kafin karin kumallo (canza wurin allura a kowane lokaci). A cikin lokuta na musamman, likita na iya yin allurar a / m na miyagun ƙwayoyi. An hana / shigarwar insulin na matsakaici tsaka! An zabi allurai daban-daban kuma sun dogara da abubuwan da ke cikin glucose a cikin jini da fitsari, halayen hanyar cutar. Yawanci, allurai sune 8-24 IU sau 1 a rana. A cikin manya da yara masu ƙarfin jijiyoyin insulin, ƙwaƙwalwar ƙasa da 8 IU / rana na iya isa, a cikin marasa lafiya da rage ƙarfin jiyya - fiye da 24 IU / rana. A adadin yau da kullun ya wuce 0.6 IU / kg, - a cikin nau'i na injections 2 a wurare daban-daban. Marasa lafiya da ke karɓar IU 100 ko sama da haka a kowace rana, lokacin da ake maye gurbin insulin, yana da kyau a asibiti. Canja wurin daga wannan magani zuwa wani ya kamata a gudanar da shi a karkashin kulawar glucose jini.
Aikin magunguna
Matsakaici insulin. Yana rage maida hankali na glucose a cikin jini, yana kara yawanshi ta hanyar kyallen takarda, yana inganta lipogenesis da glycogenogenesis, sunadaran gina jiki, yana rage yawan samarda glucose ta hanta.
Yana hulɗa tare da takamaiman mai karɓa a kan sel na waje kuma yana samar da mahaɗar insulin na insulin. Ta hanyar kunna kwayar cAMP (a cikin ƙwayoyin mai da ƙwayoyin hanta) ko kai tsaye cikin sel (tsokoki), ƙwaƙwalwar mai ɗaukar insulin ɗin tana ta motsa hanyoyin cikin ciki, gami da kira na enzymes masu yawa (hexokinase, pyruvate kinase, glycogen synthetase, da sauransu). Rage glucose na jini ya faru ne saboda karuwa a cikin jijiyoyin ƙwayoyin cuta na ciki, karuwar karɓa da kuma ƙaddara kyallen takarda, haɓakar lipogenesis, glycogenogenesis, haɗin furotin, raguwa a cikin yawan samar da glucose ta hanta (rage raguwar glycogen), da sauransu.
Bayan allurar sc, tasirin yana faruwa a cikin awanni 1-1.5. Matsakaicin sakamako yana cikin tazara tsakanin sa'o'i 4-12, tsawon lokacin aiki shine awanni 11-24, gwargwadon abun da ya shafi insulin da kashi, yana nuna mahimmancin rikice-rikice na ciki da na ciki.
Side effects
Allergic halayen (urticaria, angioedema - zazzabi, ƙarancin numfashi, saukar karfin jini),
hypoglycemia (pallor na fata, ƙara yawan shaye shaye, gumi, palpitations, rawar jiki, yunwar, damuwa, damuwa, paresthesias a bakin, ciwon kai, nutsuwa, rashin bacci, tsoro, yanayi na bacin rai, tashin hankali, hali mai ban mamaki, rashin motsi, magana da rikicewar magana da hangen nesa), hauhawar jini,
hauhawar jini da cututtukan cututtukan cututtukan jini (a ƙarancin allurai, injections, abinci mara kyau, tare da zazzabi da cututtukan fata): amai, ƙishirwa, raguwar ci, fuska mai narkewa),
mai rauni mara nauyi (har zuwa cigaban premaose da coma),
raunin gani na hankali (yawanci a farkon farawa),
rigakafi na rigakafi da insulin na mutum, karuwa a titin na anti-insulin kwayoyin, tare da karuwa a cikin glycemia,
hyperemia, itching da lipodystrophy (atrophy ko hauhawar mai mai subcutaneous) a wurin allurar.
A farkon jiyya - ƙaiƙayi da nakasasshen ƙwaƙwalwa (na ɗan lokaci ne kuma sun ɓace tare da ci gaba da jiyya). Bayyanar cututtuka: gumi, palpitations, rawar jiki, yunwar, damuwa, paresthesia a cikin bakin, pallor, ciwon kai, rashin barci, rashin bacci, tsoro, yanayi na rashin damuwa, tashin hankali, hali mai ban mamaki, rashin motsi, magana da hangen nesa, hauhawar jini, tashin hankali.
Jiyya: idan mai haƙuri yana sane, an umurce shi da dextrose na baka, s / c, i / m ko iv allura glucagon ko iv hypertonic dextrose. Tare da haɓakar ƙwayar ƙwayar cuta na jini, 20-40 ml (har zuwa 100 ml) na maganin 40% dextrose ana shigar da shi cikin rafi har sai mai haƙuri ya fito daga cikin warin.
Umarni na musamman
Kafin ɗaukar insulin daga murfin, ya zama dole a bincika gaskiyar mafita. Lokacin da jikin ƙasashen waje suka bayyana, girgijewa ko hazowar abun a kan gilashin kwalban, ba za'a iya amfani da maganin ba.
Zazzabi na insulin da ke cikin yakamata ya zama zazzabi a dakin.
Yawan insulin dole ne a daidaita shi yayin da ake fama da cututtukan da ke kama da cuta, idan aka samu matsalar raguwar cututtukan thyroid, cutar Addison, cututtukan jini, rashin lafiyar koda da kuma cutar sankarau a cikin mutane sama da shekaru 65.
Abubuwan da ke haifar da cututtukan hypoglycemia na iya zama: wucewar insulin, maye gurbin miyagun ƙwayoyi, tsallake abinci, amai, gudawa, damuwa na jiki, cututtukan da ke rage buƙatar insulin (cututtukan haɓaka na hanta da hanta, da hauhawar jini a cikin adrenal cortex, pituitary ko thyroid gland shine yake, canjin wuri injections (alal misali, fata akan ciki, kafada, cinya), haka kuma ma'amala da wasu kwayoyi. Zai yiwu a rage taro na glucose a cikin jini yayin canja wurin mai haƙuri daga insulin dabbobi zuwa insulin ɗan adam. Canza haƙuri ga insulin ɗan adam ya kamata koyaushe a likitanci kuma za'ayi shi kawai a ƙarƙashin kulawar likita.
Halin haɓaka rashin ƙarfi na hypoglycemia zai iya lalata ikon marasa lafiya don taka rawa sosai ga zirga-zirgar ababen hawa, kazalika da kula da injuna da injuna.
Marasa lafiya da ke fama da ciwon sukari na iya dakatar da ɗan ƙanƙanin hypoglycemia da suke ji ta hanyar cin sukari ko abinci mai girma a cikin carbohydrates (ana ba da shawarar cewa koyaushe kuna da akalla 20 g na sukari tare da ku). Game da maganin da aka canjawa wuri, yana da mahimmanci don sanar da likitan halartar don yanke shawara game da buƙatar gyaran jiyya. A lokacin daukar ciki, ya zama dole a la’akari da raguwa (I trimester) ko karuwa (II-III trimesters) na bukatun insulin. Lokacin kuma kai tsaye bayan haihuwa, buƙatun insulin na iya raguwa kwatsam. Yayin shayarwa, ana buƙatar saka idanu kowace rana don watanni da yawa (har sai an daidaita buƙatar insulin).
Haɗa kai
Magunguna ba tare da maganin wasu magunguna ba.
Tasirin hypoglycemic yana haɓaka ta hanyar sulfonamides (gami da magunguna na hypoglycemic na baka, sulfonamides), MAO inhibitors (ciki har da furazolidone, procarbazine, selegiline), inhibitors na carbonic anhydrase inhibitors, ACE inhibitors, ACE inhibitors, NSAIDs (gami da salicylates), anabolic (ciki har da stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, phenfluramine, Li + shirye-shirye, pyridoxine, quinidine, quinine, chloroquin
Hypoglycemic effects na sosai glucagon, girma hormone, corticosteroids, na baka hana, estrogens, thiazide da madauki diuretics, BCCI, thyroid hormones, heparin, sulfinpyrazone, sympathomimetics, danazol, tricyclics, clonidine, alli antagonists, diazoxide, morphine, marijuana, nicotine, phenytoin, epinephrine, H1-histamine mai hana masu tallatawa.
Beta-blockers, reserpine, octreotide, pentamidine zasu iya haɓakawa da raunana tasirin hypoglycemic na insulin.
Alamu don amfani da sunayen kasuwancin magani
Amfani da maganin yana nunawa ga nau'in ciwon sukari da ke dogaro da cutar siga. Haka kuma, far yakamata ya kasance tsawon rayuwa.
Insulin kamar yadda Isofan magani ne na ɗan adam wanda aka tsara ta irin waɗannan halaye:
- type 2 ciwon sukari (insulin-dogara),
- hanyoyin tiyata
- tsayayya da wakilai na hypoglycemic da aka dauka ta wani ɓangare na wahalar magani,
- cututtukan cututtukan mahaifa (in babu tasirin maganin cutar cin abinci),
- ilimin cututtukan zuciya
Kamfanonin magunguna suna samar da insulin na ɗan adam ta asali a ƙarƙashin sunaye daban-daban. Mafi mashahuri sune Vozulim-N, Biosulin-N, Protafan-NM, Insuran-NPH, Gensulin-N.
Wasu nau'ikan insulin isofan kuma ana amfani dasu da sunayen kasuwancin da ke gaba:
- M
- Humulin (NPH),
- Pensulin,
- Isofan insulin NM (Protafan),
- Actrafan
- Kari N,
- Biogulin N,
- Protafan-NM Penifill.
Yana da kyau a lura cewa amfani da kowane iri ɗaya na insulin Isofan ya kamata a yarda da likita.
Sashi da gudanarwa
Umarnin don amfani da insulin Isofan ya bayyana cewa ana gudanar dashi sau da yawa sau biyu a rana kafin karin kumallo (minti 30-45). A wannan yanayin, kuna buƙatar canza wurin allurar yau da kullun kuma adana sirinji da aka yi amfani da shi a zazzabi a ɗakin, da kuma sabo a cikin firiji.
Wasu lokuta ana gudanar da maganin ta intramuscularly. Kuma hanyar da ake amfani da ita wajen amfani da insulin matsakaici ba a amfani da ita.
Ana yin lissafin sashi daban-daban ga kowane mara lafiya, gwargwadon matakin yawan sukari a cikin magudanan kwayoyin halitta da kuma cutar cutar. A matsayinka na mai mulki, matsakaiciyar maganin yau da kullun ya tashi daga 8-24 IU.
Idan marasa lafiya suna da rashin lafiyar insulin, to, mafi kyawun adadin maganin yau da kullum shine 8 IU. Tare da rauni mara kyau na kwayoyin, sashi yana ƙaruwa - daga 24 IU kowace rana.
Lokacin da yawan ƙwayar yau da kullun ya fi 0.6 IU ta 1 kilogiram na taro, to ana yin allura 2 a sassa daban daban na jiki. Marasa lafiya tare da kashi 100 na yau da kullum na 100 IU ko fiye ya kamata a asibiti idan an maye gurbin insulin.
Haka kuma, lokacin canja wuri daga wani nau'in samfurin zuwa wani, ya zama dole don saka idanu cikin abubuwan sukari.
Rashin Amincewa da Yawan doauka
Yin amfani da insulin na mutum zai iya haifar da alamun rashin lafiyar. Mafi yawan lokuta, shine angioedema (hypotension, shortness of fever, zazzabi) da urticaria.
Hakanan, wuce sashi zai iya haifar da hauhawar jini, ta bayyanar da alamu masu zuwa:
- rashin bacci
- fata fata,
- bacin rai
- hyperhidrosis
- tsoro
- m jihar
- palpitations
- ciwon kai
- rikice,
- rikicewar vestibular
- yunwa
- rawar jiki da kaya.
Abubuwan da ke haifar da sakamako sun haɗa da acidicis na sukari da hyperglycemia, waɗanda ke fitowa ta fuskoki a fusace, amai, abinci, da ƙishirwa. Mafi sau da yawa, irin waɗannan yanayi suna haɓakawa da asalin cututtukan da ke kama da zazzabi, lokacin da aka rasa allura, sashin ba daidai ba ne, kuma idan ba a bi abincin ba.
Wani lokacin wani sahihanci yakan faru. A cikin mawuyacin yanayi, yanayin precoatous da coma na haɓaka.
A farkon magani, rikicewar rikicewar rikice rikice a cikin aikin gani na iya faruwa. Hakanan ana ƙara yawan haɓakar ƙarar rigakafin jikin insulin tare da ci gaba na glycemia da halayen immunological na yanayin giciye tare da insulin ɗan adam.
Sau da yawa shafin allurar yakan kumbura da ƙaiƙayi. A wannan yanayin, ƙananan ƙwayoyin tsoka mai ƙwanƙwasa jini ko atrophies. Kuma a farkon matakin farji, kurakurai masu raɗaɗi na wucin gadi da edema na iya faruwa.
Idan aka samu karin yawan magunguna na hormonal, matakin suga na jini yakan ragu sosai. Wannan yana haifar da hypoglycemia, kuma wani lokacin mai haƙuri ya faɗi cikin rashin lafiya.
Idan kashi ya ɗan ɗanɗana kaɗan, ya kamata ku ɗauki abinci mai yawan carb (cakulan, farin burodi, yi, alewa) ko kuma ku sha abin sha mai daɗi. Game da kasala, ana ba da ma'anar dextrose (40%) ko glucagon (s / c, v / m) ga mai haƙuri a ciki / ciki.
Lokacin da mai haƙuri ya sake farkawa, ya zama dole don ciyar da shi abinci mai arziki a cikin carbohydrates.
Wannan zai hana komawar haila da cututtukan zuciya.
Yaya aiki?
Isofan insulin ilimin injin ɗan adam yana shafar jikin mutum, yana yin tasirin hypoglycemic. Wannan magani yana cikin hulɗa tare da masu karɓar cytoplasmic na ƙwayar sel. Wannan yana haifar da hadaddun masu karɓar insulin. Aikinsa shine yin aiki da karfi wanda ke gudana a cikin sel kansu, da kuma taimakawa wajen hada kwayoyin enzymes masu aiki.
Rage yawan sukari a cikin jini yana faruwa ne ta hanyar kara zirga zirgar sufuri a cikin kwayar, kazalika da rage saurin fitar da sukari, ta hanyar taimakawa wajen daukar ruwa. Wani fa'idar insulin ɗan adam shine haɗin furotin, kunnawa na lithogenesis, glycogenogenesis.
Lokacin tsawon wannan maganin yana yin daidai ne daidai da ƙimar shan maganin a cikin jini, kuma tsarin sha yana dogara da hanyar gudanarwa da kuma maganin. Sabili da haka, sakamakon wannan magani ya sha bamban a cikin marasa lafiya daban-daban.
A bisa ga al'ada, bayan allura, sakamakon maganin yana farawa bayan sa'o'i 1.5. Babban ganuwa yana faruwa a aya 4 bayan an sha maganin. Tsawon lokacin aiki shine awoyi 24.
Yawan sha Isofan ya dogara da masu zuwa:
- Wurin allurar (buttock, ciki, cinya),
- Mai aiki da hankali
- Kashi.
Kodan ya fitar da wannan maganin.
Yadda ake amfani: alamomi don amfani
Dangane da umarnin don amfani da Isofan, dole ne a gudanar da shi sau biyu a rana: da safe da maraice kafin abinci (mintuna 30-40 kafin cin abinci). Dole ne a canza wurin allurar a kowace rana, ya kamata a adana sirinji da aka yi amfani da shi a al'ada, zazzabi na al'ada, kuma sabon ya kamata ya kasance cikin marufi, a cikin firiji. Da wuya, wannan maganin yana shiga cikin tsoka, amma kusan ba a ciki, saboda insulin ne mai matsakaici.
Ana kirga kashi na wannan magungunan daban-daban ga duk wanda ke fama da ciwon sukari, tare da tattaunawa da likitan da ke halarta. Ya danganta da yawan sukari a cikin plasma da kuma ƙayyadadden ciwon sukari. Matsakaicin adadin yau da kullun, al'ada yana bambanta tsakanin 8-24 IU.
Idan akwai rashin lafiyar insulin, to ya zama dole a dauki fiye da 8 IU a kowace rana, idan ba a hango maganin da kyau ba, ana iya kara kashi zuwa 24 ko fiye da IU a yayin rana. Idan kashi na yau da kullum na miyagun ƙwayoyi ya kamata ya wuce 0. 6 IU a kilogram na nauyin jikin mai haƙuri, to ana yin allura 2 a lokaci guda a wurare daban-daban.
- Urticaria,
Doaukar ƙarin maganin wannan ƙwayar cuta ya kasance tare da hypoglycemia da coma. Za a iya magance yawan maganin idan kun ɗauki abinci mai yawa a cikin carbohydrates (cakulan, alewa, kukis, shayi mai zaki).
Idan kuwa aka samu asarar hankali, to sai a samarda maganin Dextrose ko Glucagon a cikin mara lafiya. Lokacin da hankali ya dawo, ya kamata a ba mai haƙuri abinci a cikin carbohydrates. Wannan zai sa ya yiwu a nisanci duka cututtukan mahaifa da komawar mahaifa.
Insulin-isophan: umarnin don amfani da dakatarwar
Sunan Latin: karancinum
Lambar ATX: A10a
Aiki mai aiki: insulin-injin-injin ɗan adam
Mai masana'anta: Novo Nordisk, Denmark
Yanayin hutu daga kantin magani: Da takardar sayan magani
Yanayin ajiya: t tsakanin digiri 2-8
Ranar cikawa: Shekaru 2
Ana amfani da ɗan adam na injinin inulin insulin don lura da yanayin da ke tattare da rashin isasshen ƙwayar halittar jikin mutum ta ƙirar insulin. Babu wani magani tare da wannan suna akan siyarwa, tunda wannan nau'i ne na kayan aiki, amma akwai analogues. Misalin ingantaccen irin wannan abun akan siyar shine rinsulin.
Isofan insulin: zan iya amfani dashi tare da wasu magunguna
Effectara tasirin cutar hypoglycemic (normalization of sugar sugar) Isofan symbiosis tare da:
- Sulfonamides,
- Chloroquinine
- ACE inhibitors / MAO / carbonic anhydrase,
- Ethanol
- Mebendazole,
- Yana nufin ma'anar ɓangaren ƙungiyar tare da maganin anabolic steroids,
- Fenfluramine
- Magungunan Tetracycline
- Clofibrate
- Magunguna na ƙungiyar theophylline.
Tasirin hypoglycemic (kawo adadin sukari a cikin jini zuwa al'ada) an rage saboda symbiosis na Isofan tare da irin waɗannan kwayoyi:
- Somatropin
- Epinephrine
- Abubuwan hanawa
- Epinephrine
- Phenytoin
- Masu maganin kishi.
Yawan sukari a cikin jini yana raguwa sakamakon symbiosis na insulin Isofan tare da thiazide da loop diuretics, tare da BMCC, haka kuma tare da kwayoyin hodar iblis, cututtukan zuciya, Klondin, Danazole, sulfinpyrazone. Morphine, marijuana, barasa da nicotine kuma suna rage sukarin jini. Marasa lafiya masu ciwon sukari kada su sha ko hayaki.
Bayan haɗin gwiwar gudanar da magungunan da ba su dace ba tare da Isofan, abubuwan da zasu iya haifar da hauhawar jini da kuma:
- Sauyawa zuwa wani magani wanda ke kula da matakan sukari na yau da kullun,
- Ciwon sukari na amai
- Ciwon sukari mai haifar da gudawa
- Karuwar jiki kaya
- Cututtukan da ke buƙatar buƙatar insulin (ƙwayar ƙwayar cuta, ƙwanƙwasa jini, gazawar hanta, gazawar koda),
- Lokacin da mara lafiya bai ci abinci akan lokaci ba.
- Canjin wurin allura.
Cutar da ba ta dace ko dogon lokaci tsakanin injections na iya haifar da hyperglycemia (musamman a cikin yanayin nau'in ciwon sukari na 1). Idan ba a daidaita maganin a cikin lokaci ba, mai haƙuri na iya faɗuwa cikin coma ketoacidotic.
Marasa lafiya da ke amfani da wannan magani ya girmi shekara sittin da haihuwa, kuma har ma fiye da haka wanda ke da nakasa aiki na ƙwayar hanta, koda, hanta, ya wajaba a nemi shawara tare da halartar ƙwararren likita game da yadda ake yin insulin Isofan. Dole ne a dauki matakan iri ɗaya idan mai haƙuri yana fama da cututtukan hypopituitarism ko cutar Addison.
Yadda ake kwantar da hankali: umarni na musamman
Kafin ka sha maganin a cikin sirinji, bincika idan maganin yana da gajimare. Ya kamata a bayyana gaskiya. Idan flakes, jikin baƙi sun bayyana, mafita ta zama gajimare, hazo ya haifar, ba za a iya amfani da maganin ba.
Zazzabi na miyagun ƙwayoyi da aka sarrafa ya kamata ya zama zazzabi dakin Idan a yanzu kuna da mura ko ƙari tare da kowane cuta, to ya kamata ku nemi shawarar likitan ku game da ƙimar. Lokacin maye gurbin miyagun ƙwayoyi, wannan ya kamata a yi a ƙarƙashin kulawar likita, yana da hankali don zuwa asibiti.
Cutar ciki, lactation da insulin Isofan
Matan da ke da juna biyu masu ciwon sukari na iya ɗaukar Isofan insulin, ba zai kai ga tayin cikin mahaifa ba. Kuna iya amfani da shi da uwaye masu shayarwa, waɗanda aka tilasta su zauna tare da wannan cutar. Yana da mahimmanci a san cewa yayin daukar ciki a cikin farkon farkon, buƙatar insulin ya ragu, kuma a cikin watanni na biyu da na uku yana ƙaruwa.
Alamu don amfani
Babban nuni shine lura da ciwon sukari na 1, amma a wasu lokuta ana iya yin allurar a gaban wani nau'in insulin mai dauke da cutar. Duk wani sunan kasuwanci na isophane ya dace da kula da mutumin da baya shan kayan hypoglycemic saboda cikakken ko juriya. Commonlyarancin kullun, ana amfani da magani a cikin mata masu juna biyu da nau'in ciwon sukari na biyu.
Abun ciki da sakin siffofin
1 ml na bayani ya ƙunshi raka'a 100 na abubuwa masu aiki. Abubuwa masu taimako - furotin protamine, ruwa mai matsewa don injections, crystalline phenol, sodium dihydrate phosphate, glycerol, metacresol.
Dakatarwa don yin allura, m. Kwalba ɗaya ta ƙunshi 3 ml na abu. A cikin kunshin ɗaya akwai katako guda 5 ko ana siyarwa a cikin kwalba ɗaya nan da nan 10 ml na miyagun ƙwayoyi.
Hanyoyin warkarwa
Isofan insulin shine matsakaicin tsawon lokacin daukar nauyin hypoglycemic wakili, wanda aka yi ta amfani da fasahar DNA.
Bayan subcutaneous management, the endogenous hormone ya danganta ga mahallin insulin, wanda ya haifar da kwayar halittar enzyme da yawa - hexokinase, pyruvate kinase da sauransu.
Godiya ga abu da aka gabatar daga waje, sararin cikin jiki wanda ke motsa jini yana ƙaruwa, saboda abin da ƙwayayen ke ɗaukar shi sosai, kuma yawan kumburin sukari da hanta ke raguwa sosai. Tare da yin amfani da kullun, miyagun ƙwayoyi suna haifar da hanyoyin da ake amfani da lipogenesis, glycogenogenesis da proteinogenesis.
Tsawon lokacin aiki da yawan farawa a cikin mutane daban-daban ya dogara da dalilai da yawa, musamman kan saurin tafiyar matakai. Me ake nufi - wannan tsari na mutum ne.
Matsakaici, tunda wannan shine hormone na matsakaicin matsakaici na aiki, farkon tasirin yana tasowa a cikin awa daya da rabi daga lokacin da ake gudanar da aikin ƙarƙashin ƙasa.
Tsawon lokacin sakamako shine awowi 24, mafi girman hankali yana faruwa a cikin awanni 4-12.
Ana tunawa da miyagun ƙwayoyi ba tare da bambanci ba, ana cire shi ta hanyar kodan, tsananin tasirin ya dogara kai tsaye kan wurin allurar (ciki, hannu ko cinya). Magungunan ba ya ƙetare shingen mahaifa kuma zuwa cikin madarar nono, saboda haka an ba shi izini ga masu juna biyu da kuma iyayen da aka haifa kwanan nan.
Hanyar aikace-aikace
Matsakaicin farashin magani a Rasha shine 1075 rubles a kowace fakiti.
Don sa subcutaneously, sau ɗaya a rana, a wurare daban-daban. Mitar allura a wuri guda kada ya zarce fiye da lokacin 1 a wata daya, don haka ana canza wurin gudanar da magunguna a kowane lokaci.
Kafin amfani kai tsaye, ampoules ɗin an mirgine a cikin dabino.
Jagorar allura ta asali - magani bakararre, an saka allurar subcutaneously a wani kusurwa na digiri 45 a cikin rikicewar murkushewa, to, an lalata wurin sosai. Dosages ana zaɓa ta likita daban-daban.
A lokacin daukar ciki da shayarwa
An yarda da miyagun ƙwayoyi don amfani a waɗannan lokutan.
Contraindications da Kariya
Waɗannan sun haɗa da: rashin haƙuri zuwa takamaiman abu mai aiki da ƙananan matakan sukari a wani lokaci.
Hulɗa da miyagun ƙwayoyi
Rage tasirin miyagun ƙwayoyi: glucocorticoids na tsari, hana maganin hana haihuwa, estradiol da progesterone, steroids anabolic, diuretics, antidepressants, hormones thyroid.
Efficiencyara yawan aiki mai kyau: barasa, salicylates, sulfonamides da beta-blockers, MAO inhibitors.
Side effects da yawan abin sama da ya kamata
Hypoglycemia ko lipodystrophy mai yiwuwa ne idan ba a bin ƙa'idodin allura da allurar da aka tsara. Commonarancin gama gari sune tasirin sakamako na tsari a cikin halayen halayen rashin lafiyan, ƙarancin numfashi, saukar da saukar karfin jini, hyperhidrosis da tachycardia.
Game da yawan abin sama da ya wuce, alamomin alamu na karancin sukari na jini ya bayyana: jin karfi na yunwar, rauni, asarar hankali, tsananin farin ciki, gumi, sha'awar cin Sweets, a lokuta masu tsanani - rikicewa. Alamar sassauci ana dakatar da ciwan carbohydrates mai sauri, matsakaici - tare da injections na dextrose ko glucose. Yanayin mawuyacin hali yana buƙatar kiran gaggawa ga likitoci a gida.
Rinsulin PNH
Geropharm-bio LLC, Rasha
Matsakaicin farashin a Rasha - 1000 rubles a kowace kunshin.
Rinosulin cikakkiyar analog ne kuma yana kunshe da insulin matsakaici na tsawon lokaci. Wannan nau'i na miyagun ƙwayoyi yana da kyau saboda ba ya buƙatar kullun subcutaneous.
Ribobi:
- Tasiri
- Rasha ta samarwa.
Yarda:
- Ba mafi arha ba
- Ana iya samun sakamako masu illa.
Humulin NPH
Eli Lilly Gabas, Switzerland
Matsakaicin farashin a Rasha - 17 rubles.
Humulin NPH analog ne na matsakaicin raɗaɗɗarwa.
Ribobi:
- Costarancin farashi
- M don amfani.
Yarda:
- Akwai sakamako masu illa
- Bai dace da kowa ba.
Duk bayani game da Biosulin N akan Pharmacy.ru
Kuna adana 104,00 rub.
na 1 naúra - 183,00 rub.
Kuna ajiye 49.00 rub.
na 1 naúra - 438,00 rub.
Ka ajiye 99,00 rub.
na 1 naúra - 256,00 rub.
Pharmstandard-Ufa Vitamin Shuka, JSC Russia Ciwon sukari Yana nufin
Hypoglycemic wakili, matsakaici insulin.
Sakin Fom
- 5 ml - kwalabe na gilashin launi (1) - fakitoci. 5 ml - kwalabe na gilashin mara launi (2) - murhun tantanin halitta (1) - fakitoci. 5 ml - flasks of glassless (3) - blister fakitoci Dakatar da ayyukan subcutaneous na 100 IU / ml - 3 ml na shirye-shiryen zuwa cikin gilashin gilashin launuka mara launi, an rufe hatimi tare da haɗin kai, don amfani da Penmatic Pen alkalami-dakatarwa ga subcutaneous management na 100 ME / ml - 3 ml na miyagun ƙwayoyi a cikin katako na gilashin tsaka tsaki mara launi, an rufe shi tare da haɗin kai. An ɗora Kwatin a cikin takaddun sirinji na BiomatikPen 2 don amfanin guda. A kan sirinji 5 Biomatikpen 2 amfani da guda ɗaya tare da katako a cikin kunshin.
Bayanin sigar sashi
- Farar fata dakatarwa. Lokacin tsaye, dakatarwar ta zauna, samar da hazo. Madaukaki ya bayyana sarai, ba ta da launi ko kusan launi. A sauƙaƙe za a sake tura shi cikin saurin girgiza kai. Dakatar da ayyukan gwamnatin s / c na farin launi, lokacin da yake tsaye, dakatarwar ta daidaita, yana haifar da fararen fari. Madaukaki ya bayyana sarai, ba ta da launi ko kusan launi. A sauƙaƙe za a sake tura shi cikin saurin girgiza kai.
Pharmacokinetics
Orazantawa Cikakken cikakken ɗaukar ciki da kuma farkon tasirin insulin ya dogara da wurin allura (ciki, cinya, gindi), kashi (ofaukar insulin injection), da kuma yawan insulin a cikin shiri.
Rarraba a cikin kyallen ba daidai ba. Bai ƙetare katangar ƙwarya ba kuma ba a keɓance shi da madara ba. An lalata kwayoyin halittar jini ta hanyar insulinase musamman a cikin hanta da kodan.
An fitar da Excretion cikin fitsari - 30-80%.
Yanayi na musamman
Ba za ku iya amfani da miyagun ƙwayoyi ba Biosulin® N idan, bayan girgizawa, dakatarwar ba ta zama fari ba kuma gajimare. Gabanin tushen ilimin insulin, lura da kullun matakan glucose na jini ya zama dole.
Baya ga yawan wuce haddi na insulin, abubuwan da ke haifar da rashin ƙarfi a cikin jiki na iya haɗawa da maye gurbin miyagun ƙwayoyi, tsallake abinci, amai, gudawa, haɓaka aiki na jiki, cututtukan da ke rage buƙatar insulin (lalacewar hanta da ƙwaƙwalwar hanji, hauhawar ƙwayar fata adrenal, pituitary ko glandar thyroid), canjin wurin allura, da kuma hulɗa tare da wasu kwayoyi.
Rashin tsarin allurar rigakafi ko katsewa a cikin gudanarwar insulin, musamman ma a cikin marassa lafiya da ke fama da cutar sankarar mahaifa guda 1, na iya haifar da cutar hauka. Yawancin lokaci, alamun farko na hyperglycemia suna haɓaka hankali a kan sa'o'i da yawa ko kwanaki.
Waɗannan sun haɗa da ƙishirwa, yawan urination, tashin zuciya, amai, amai, ja, bushewar fata, bushewar baki, rashin ci, kamshin acetone a cikin iska mai ƙuna. Idan ba a kula da shi ba, zazzabin hyperglycemia a cikin nau'in 1 na ciwon sukari na iya haifar da haɓakar cutar ketoacidosis mai barazanar rayuwa.
Yawan maganin insulin dole ne a gyara shi saboda aikin thyroid mai rauni, cututtukan Addison, cututtukan zuciya, hanta da / ko aikin koda, da kuma ciwon sukari a cikin mutane sama da shekaru 65. Hakanan ana iya buƙatar gyara kashi na insulin idan mai haƙuri ya ƙaru da ƙarfin motsa jiki ko ya canza abincin da aka saba.
Cututtukan haɗaka (musamman masu kamuwa da cuta) da yanayi tare da zazzabi suna ƙaruwa da buƙatar insulin. Canjin daga wani nau'in insulin zuwa wani yakamata a gudanar dashi ƙarƙashin ikon matakan glucose na jini. Miyagun ƙwayoyi na rage haƙuri haƙuri.
Sakamakon yiwuwar hazo a cikin wasu catheters, ba a bada shawarar yin amfani da miyagun ƙwayoyi a cikin farashin matatun.
Tasiri a kan ikon tuka motoci da hanyoyin sarrafawa A yayin gudanar da farawar insulin, canjin nau'inta, ko tare da tasiri mai tasiri na jiki ko na hankali, zai yuwu a rage karfin tuƙi mota ko sarrafa abubuwa daban-daban, tare kuma da yin wasu ayyukan masu haɗari waɗanda ke buƙatar haɓaka hankali da saurin halayen psychomotor Maganin dabara yayin amfani da insulin a cikin kayan katako don amfani dashi tare da alkalami mai ƙyalli na BiomatikPen. Ya kamata a faɗakar da mai haƙuri game da buƙatar bin umarnin a hankali cikin umarnin don amfani da alkairin sirinji don gudanar da insulin. Kafin amfani, tabbatar cewa babu lalacewa (alal misali, fashe) akan kicin ɗin tare da Biosulin® N. Kada kayi amfani da kirinin idan akwai wasu lahani bayyananne. Kada ku yi amfani da Biosulin® N idan, yayin hada abubuwa da ke cikin katun bisa ga umarnin don amfani, insulin ɗin ba ta zama fari fat da kuma girgije. Kada ku yi amfani da Biosulin N idan ya ƙunshi flakes bayan haɗuwa. Kada ku yi amfani da Biosulin N idan ingantaccen farin barbashi ya bi zuwa kasan ko ganuwar katun, yana haifar da "yanayin yanayin sanyi". Bayan an shigar da kabad a cikin sirinji na siriri, yakamata a riƙa tsinkayen launin shuɗi ta taga mai riƙe da akwatin. Kafin sanya katun a cikin sirinji, juya katun a sama da ƙasa domin ƙwallon gilashi na motsa daga ƙarshen zuwa ƙarshen kabad ɗin. Ya kamata a maimaita wannan hanyar aƙalla sau 10 har sai dukkanin ruwan ya zama fari da girgije. Nan da nan bayan wannan, allura wajibi ne. Idan katangar ya riga ya shiga cikin alkairin sirinji, ya kamata ka jujjuya shi tare da kicin a ciki sama da ƙasa a ƙalla sau 10. Dole ne a maimaita wannan hanyar kafin kowane allura. Bayan allura, allura ya kamata ya kasance a karkashin fata na akalla aƙiƙa 6. Riƙe maɓallin har sai an cire allura gaba ɗaya daga fata, don haka tabbatar da ingantaccen tsarin kulawa da yiwuwar jini ko lymph shiga cikin allura ko kuma kiringin insulin ya iyakance. Katin tare da miyagun ƙwayoyi Biosulin N an yi shi ne don amfanin mutum kawai kuma kada a cika shi. Hanyar allura • Ta amfani da yatsunsu biyu, tattara wani mayafin fata, saka allura a cikin gindin murfin a kusurwar kusan 45 °, kuma saka insulin a ƙarƙashin fata. • Bayan allura, allura ya kamata ya kasance a karkashin fata na akalla a kalla 6 don tabbatar da cewa an saka insulin a ciki. • Idan jini ya bayyana a wurin allura bayan cire allura, a hankali shafa matattarar allura tare da kwantar da hancin da sinadaran hana ruwa (kamar giya). • Wajibi ne a canza wurin allurar.
- insulin-isophan (injinin ɗan adam) 100 IU Masu haɓaka: zinc oxide, sodium hydrogen phosphate, protamine sulfate, metacresol, crystalline phenol, glycerol, d / i ruwa.
Abubuwan sakamako na Biosulin N
- Daga gefen metabolism: yanayin hypoglycemic (pallor na fata, karuwar gumi, jin ciwon palpitations, rawar jiki, yunwa, tashin hankali, paresthesia a bakin, ciwon kai). Mai tsananin rashin ƙarfi na hypoglycemia na iya haifar da haɓakar ƙwaƙwalwar ƙwayar cuta. Allergic halayen: da wuya - fatar fata, fitsarin Quincke, a wasu yanayi - tashin hankalin anaphylactic. Abubuwan da suka shafi gida: hyperemia, kumburi da itching a wurin allurar, tare da tsawan amfani - lipodystrophy a wurin allurar. Sauran: edema, kurakurai na yau da kullun kurakurai (yawanci a farkon farji).
Hulɗa da ƙwayoyi
Akwai kwayoyi da yawa waɗanda ke shafar buƙatar insulin.
Tasirin hypoglycemic na insulin an inganta shi ta hanyar maganganu na maganin hypoglycemic na bakin, MAO inhibitors, masu hana beta-blockers, ACE inhibitors, sulfanilamides, steroids anabolic, carbonic anhydrase inhibitors, bromocriptine, octreotide, tetracyclines, kefiloflindofilfilimin klal klama shirye-shirye dauke da ethanol. Sakamakon maganin hypoglycemic na insulin an rage shi ta hanyar maganin hana haihuwa, corticosteroids, hormones thyroid, thiazide diuretics, heparin, maganin tricyclic antidepressants, sympathomimetics, danazole, clonidine, allunan tashar alli, diazoxide, morphine, not, not.Underarfafawar tasirin reserpine da salicylates, duka raunana da haɓaka a cikin aikin miyagun ƙwayoyi yana yiwuwa
Farashi don Biosulin N a wasu biranen
Biosulin N a Moscow, Biosulin N a St. Petersburg, Biosulin N a Novosibirsk, Biosulin N a Yekaterinburg, Biosulin N a Nizhny Novgorod, Biosulin N a Kazan, Biosulin N a Chelyabinsk, Biosulin N a Omsk, Biosulin N a Samara, Biosulin N a Rostov-on-Don, Biosulin N a Ufa, Biosulin N a cikin Krasnoyarsk, Biosulin N a Perm, Biosulin N a Volgograd, Biosulin N a Voronezh, Biosulin N a cikin Krasnodar, Biosulin N a Saratov, Biosulin N a Tyumen oda bayarwa a Moscow
Lokacin yin oda a Apteka.RU, zaku iya zaɓar bayarwa don kantin magani mafi dacewa a gare ku kusa da gidanka ko kan hanyar zuwa aiki.
Duk wuraren bayarwa a Moscow - kantin magani 696
Duk wuraren bayarwa a Moscow - kantin magani 696
Ranar bita: Afrilu 2, 2016
Karanta dukkan bita da aka buga: Bondareva Margarita
Ranar bita: 1 ga Agusta 1, 2016
Ranar bita: 19 ga Agusta 19, 2016
Ranar bita: Satumba 15, 2016
Ranar bita: 18 ga Fabrairu, 2017
Isofan na ɗan adam ɗan adam, amfani da farashin miyagun ƙwayoyi
Isofan ingantaccen inine inine, wanda ake amfani dashi don maganin warkewar marasa lafiya da masu cutar siga.
Insulin na mutum, wanda aka samo ta injiniyan ƙwaƙwalwa ta amfani da fasahar DNA, ana ɗauka magani ne na tazara.
A cikin kantin magunguna, ana sayar da shi ta hanyar dakatarwa da aka yi amfani da shi don allurar allura a ƙarƙashin fata. Farashin ya dogara da sashi, masana'anta kuma ya bambanta daga 500 zuwa 1000 rubles.
Pharmacology
Isofan - insulin, yana da tasirin hypoglycemic. Yana da alaƙa da ƙayyadaddun ƙarewar ƙwayar sel na ƙwayar cytoplasmic, sakamakon abin da aka samar da tsarin karɓar insulin. Yana taimakawa wajen haɓaka hanyoyin kwantar da hankali.
Sakamakon cewa motsa glucose a cikin sel yana ƙaruwa, adadinsa a cikin jini yana raguwa. Ana samun irin wannan sakamako ta hanyar rage yawan samuwar glucose ta hanta da kuma ƙara yawan shan shi ta hanyar kyallen takarda.
Magungunan suna yin aiki na dogon lokaci saboda saurin ɗaukar abu, wanda ke tasiri da abubuwa da yawa: yadda ake shigar insulin (ana iya allurar shi a ciki, cinya ko kuma gindi), hanyar gudanarwa, sashi.
Bayan gabatarwar kwayar halitta ta dan adam mai narkewa a karkashin fata tare da allura, kunnawarsa ya faru bayan sa'o'i daya da rabi. Magungunan suna da inganci daga 4 zuwa 12 na 12, yana aiki yayin rana.
Ana iya danganta abubuwa masu zuwa ga mahimman abubuwan Isofan: baya maida hankali a cikin madarar uwa. Rarraba cikin kyallen takarda bai yi daidai ba. Bai ƙetare mahaifa ba. Kodan daga kashi 30 zuwa 80% ne kodan ke ficewa.
Umarnin don amfani
Umarnin don amfani yana nuna babban nau'in cuta wanda ake amfani da inulin na asali - insulin-based diabetes mellitus. Jiyya a cikin wannan halin yana gudana ne a duk rayuwa. A wannan yanayin, yana da mahimmanci a bi tsarin allurar. Bugu da kari, ana amfani da Isofan don nau'in 1 da nau'in ciwon sukari na 2.
Likita na iya ba da magani idan har akwai rashin sakamako daga magunguna tare da tasirin rage sukari. Sannan ana wajabta insulin azaman magani hade.
Hakanan karuwar sukarin jini na iya zama sakamakon rikitarwa, alal misali, bayan tiyata. A wannan halin, ana iya kuma samarda insulin a matsayin magani mai wahala. An wajabta wa mata masu juna biyu masu ciwon suga.
Ana amfani da Isofan kawai don nau'in 1 da nau'in ciwon sukari na 2!
Magungunan yana contraindicated a cikin marasa lafiya yiwuwa ga rashin lafiyan halayen da ciwon hypoglycemia.
Tasirin rimarfin
Babban sakamakon illolin Isofan sune:
- Sakamakon illa game da metabolism na metabolism. An bayyana wannan a cikin nau'in pallor na fata, sutsi mai ɗaci, bugun zuciya mai sauri, bayyanar rawar jiki, mutum koyaushe yana son cin abinci, ƙwarewar tashin hankali, matsanancin ciwon kai.
- Allergy ya bayyana ta hanyar fitsarin fata, fitsarin Quincke. A cikin lokuta mafi wuya, ƙwayar ta haifar da girgiza anaphylactic.
- Kumburi na iya faruwa.
- Bayan allura, itching ko kumburi, bruising na iya faruwa. Idan maganin yana daɗewa, an kirkiro lipodystrophy.
A wannan batun, a farkon magani, ana iya aiwatar da ilimin insulin ne kawai bayan alƙawarin likita kuma a ƙarƙashin kulawarsa.
Yawan wuce haddi
Dangane da gabatarwar ƙarin ƙwayar ƙwayar cuta, mai haƙuri na iya fuskantar alamun hypoglycemia. A wannan yanayin, kuna buƙatar cin ɗan sukari ko abinci mai wadatar carbohydrates. Zai iya zama cookies, ruwan 'ya'yan itace, Sweets.
Roaddamar da Isofan mai yawa zai iya haifar da asarar hankali. An ba da shawarar ku ba da allura ta hancin allurar 40% dextrose. Ana iya gudanar da Glucagon ta intramuscularly, a cikin tazara ko tajasa.
Kariya da aminci
Lokacin amfani da Isofan, ya kamata a ɗauka a zuciya cewa idan kun allurar da miyagun ƙwayoyi a wuri guda, lipodystrophy na iya samarwa. Don hanawa, ana bada shawara don canza wurin allurar. Lokacin gudanar da aikin insulin, yakamata ku kula da sukarin jini.
Dole ne a yi amfani da kayan aiki da kyau bisa ga tsarin da likita ya tsara. In ba haka ba, hypoglycemia na iya haɓaka. Yana iya bayyana saboda rashin cin abincin. A wannan yanayin, mutum yana da jin ƙishirwa, bushewar baki, urination akai-akai, rashin lafiya mara kyau, wanda aka nuna ta hanyar tashin zuciya, har zuwa amai, asarar ci, mummunan numfashin acetone daga bakin.
Magungunan da ake sarrafawa ya kamata su kasance daga jikin baƙi, bayyananne, ba tare da laka a ƙasa ba. Kasancewarsa yana nuni da yawan guba da insulin, don haka amfani da miyagun ƙwayoyi na iya zama haɗari ga mai haƙuri.
Ya kamata Isophan ya kasance cikin zazzabi a daki lokacin gudanar da shi. Tare da cututtukan cututtukan cututtukan da aka samo saboda tabarbarewa na thyroid, hypopituitarism, sashi na magungunan da ake sarrafawa yana buƙatar daidaitawa.
Isofan ne ya rubuta ta likita idan babu wani sakamako na magani tare da magunguna masu rage sukari.
Tsallake hulɗa
Umarnin don yin amfani da miyagun ƙwayoyi ya bayyana dalla-dalla game da halayen miyagun ƙwayoyi da kamfani da amfaninsa.
Isofan injin ɗan adam yana da aiki sosai idan aka ɗauki waɗannan kwayoyi a lokaci guda:
- Hypoglycemic na bakin wakilai.
- MAO da masu hana ACE, carbonhy anhydrase.
- Sulfonamides.
- Anabolikov.
- Karafasus.
- Magunguna dauke da ethanol.
Ingancin Isofan yana raguwa lokacin amfani dashi: maganin hana haihuwa, magungunan glucocorticoid, hormones thyroid, antidepressants, morphine. Idan ba zai yiwu a soke magungunan da ke shafar aikin insulin ba, wajibi ne a faɗakar da malamin da ke halartar wannan.
Irin kwayoyi
Marasa lafiya masu ciwon sukari suna da sha'awar tambayar menene ma'anar maye gurbin insulin. An ba da shawarar yin amfani da waɗannan analogues na Isofan don magani: Humulin (NPH), Protafan-NM, Protafan-NM Penfill, Insumal, Actrafan.
Kafin canza Isofan zuwa analog, ya zama dole a nemi shawara tare da likitanka. Harkokin insulin shine babban magani. Yana buƙatar horo a ɓangaren haƙuri da lura da likita.
Ciwon sukari mellitus cuta ce mai girma, wanda, rashin alheri, ba za a iya kawar da ita gaba ɗaya. Kamar yadda kuka sani, a game da ciwon baya, akwai take hakkin ɓoyewar jijiyoyin zuciya a cikin ƙwayoyin kumburi. Kuma sau da yawa, marasa lafiya ana rubanya Isofan roba insulin. Wannan abu yana sarrafa matakin sukari a cikin jini, yana tabbatar da aiki na al'ada na jiki gaba ɗaya.
Tabbas, marasa lafiya suna sha'awar kowane ƙarin bayani game da miyagun ƙwayoyi. Ta yaya Isofan Semi-roba yake motsa jiki? Umarnin, contraindications, yiwuwar rikice-rikice a lokacin jiyya sune mahimman abubuwan da za a yi la’akari dasu a cikin labarin.
Fom ɗin saki
Ba asirin ba ne cewa cutar sankarau cuta ce da aka saba da haɗari wanda ke buƙatar yin amfani da magunguna daban-daban, gami da insulin.
"Isofan" shine sunan kasuwanci na miyagun ƙwayoyi, wanda ya kasance cakuda hade da kwayoyin halittar semisynthetic. Ana samar da magani a cikin hanyar samar da mafita don gudanar da aikin subcutaneous.
Ana sayar da maganin a cikin gilashin gilashin of 10 ml tare da sashi na 40 IU / ml. Don shirya mafita, ana amfani da tsarkakken ruwa don yin allura.
Idan wasu kwayoyi iri ɗaya tare da kayan guda ɗaya da insulin Isofan. Ma’anoninsa sune “Insuman”, “Protafan” da “Himulin”. Zai dace da nan da nan cewa irin waɗannan magungunan ana ba da izini ne kawai ta hanyar takardar sayan magani ko kuma ƙwararrun likitan dabbobi ne suka ba su.
Abin da abubuwan da magunguna ke da shi?
Isofan insulin shine hormone na kwayar halitta wanda yake da kaya iri daya kamar kayan da mutum ke samarwa. Magungunan yana rage adadin glucose a cikin jini ta hanyar inganta ayyukan lipogenesis da gluconeogenesis.
Hormone roba yana hulɗa da masu karɓar insulin-ins na masu membranes, suna aiwatar da abubuwan haɓakawa a cikin tantanin. Bayan shan miyagun ƙwayoyi, akwai kunnawa don haɗin wasu enzymes, gami da glycogen synthetases, pyruvate kinases da hexokinases.
Ana iya lura da tasirin riga sa'o'i 1-1.5 bayan gabatarwar mafita. Dangane da kashi da halaye na jikin mai haƙuri, ana lura da matsakaicin aikin insulin roba sau 4-12 bayan gudanarwa. Sakamakon yana daga awa 11 zuwa 24.
Babban alamomi don amfani
Ana amfani da miyagun ƙwayoyi "Insulin-Isofan" don ciwon sukari na mellitus na nau'in na biyu (nau'in insulin-dogara). Hakanan ana amfani dashi don maganin insulin na ɗan lokaci. Wani lokaci ana buƙatar irin wannan magani don nau'in 1 na ciwon sukari. Misali, gabatar da mafita ana bada shawara ga marassa lafiya a lokuta inda magunguna masu rage sukari ba su bayar da tasirin da ake so.
Ana buƙatar gabatarwar insulin ɗan adam bayan wasu hanyoyin tiyata. Hakanan ana amfani da wannan magani don maganin ciwon sukari na mellitus (wannan nau'in cutar ta taso a cikin mata yayin daukar ciki). An ba da shawarar gabatarwar insulin ga uwaye masu fata idan maganin rage cin abinci ba shi da tasirin da ake so.
Semi-roba-insulin "Isofan": umarnin don amfani
Tare da nau'in ciwon sukari na 2, marasa lafiya suna buƙatar maganin rayuwa. Sashi, adadin yau da kullun, jadawalin gudanarwa - duk wannan an ƙaddara ta halartar endocrinologist. Yana da mahimmanci a bi duk umarnin gwani. Akwai wasu ƙa'idodi na gaba ɗaya don amfani da Insulin-Isofan.
- Maganin shine kawai don tsarin kulawa da ƙasa. A cikin halayen da ba a sani ba, likita na iya ba da shawarar gudanar da maganin ta hanyar ƙwayar cuta. An haramta allura mai guba a ciki.
- Ba za a iya gudanar da maganin ba a wuri guda.
- Da farko kuna buƙatar girgiza kwalban sau da yawa, sannan zana adadin maganin da ake buƙata a cikin sirinji (an zaɓi sashi ɗin daban-daban).
- Ya kamata a aiwatar da allurar nan da nan bayan an cika sirinji.
Ana adana vials tare da mafita a cikin firiji a zazzabi na 2-8 digiri Celsius. Kafin gudanar da magani, kuna buƙatar auna matakin glucose a cikin jini. A kowane hali ya kamata ku yi amfani da miyagun ƙwayoyi idan kun lura da mafificin girgije, samuwar hazo akan bangon kwalban.
Shin akwai abubuwan hanawa?
Magungunan suna da wasu contraindications - waɗannan bayanan sun ƙunshi umarnin don amfani. “Insulin-Isofan” ba a ba shi izini ga marasa lafiya da ke ɗauke da cututtukan jini.
Contraindications sun haɗa da insulinoma, kazalika da rashin hankali ga abubuwan da ke cikin miyagun ƙwayoyi.
Yana da mahimmanci a lura cewa wani lokacin ma canji a wurin allurar na iya haifar da rashin lafiyar rashin lafiyar jiki da bayyanar wasu sakamako masu illa.
M sakamako masu illa
Wannan magani ya zama dole ga marasa lafiya da ke da nau'ikan kamuwa da insulin. Ko ta yaya, aikin likita yana da alaƙa da wasu rikitarwa. Wadanne abubuwa ne masu keta haddi zasu iya haifar da amfani da Isofan-insulin? Umarnin ya ƙunshi waɗannan bayanai:
- Jerin raunin da ya fi kamari na iya haɗawa da halayen rashin lafiyan, wanda ke haɗuwa da bayyanar fitsari da urticaria, raguwar hauhawar jini, hauhawar zafin jiki da bayyanuwar edema.
- Sakamakon mai haɗari na maganin insulin shine hypoglycemia, yanayin yanayin karɓar sukari jini. Kwayar cutar ta haɗa da pallor na fata, saurin bugun zuciya, damuwa, kwanciyar hankali, jin yunwar kullun. Irin wannan cin zarafin yawanci ana haɗuwa dashi da ƙarancin amfani ko rashin bin umarnin likitan. A cikin mafi yawan lokuta mawuyacin hali, cutar sikila ta haila.
- Farawa magani a wasu marasa lafiya yana da alaƙa da raunin gani. Ba shi da mahimmanci damuwa da yawa game da wannan, tunda a mafi yawan lokuta irin waɗannan sakamako masu illa suna ɓatar da kansu.
- Jerin yiwuwar rikitarwa ya haɗa da halayen ƙwayar cuta, wanda shima ya wuce yayin da jiki ya dace da wannan nau'in insulin.
- A farkon shan miyagun ƙwayoyi, halayen fata yana yiwuwa, gami da jan ciki da ƙaiƙayi. Suma suna wucewa kansu.
- Gabatarwa da manyan magunguna masu guba sun cika tare da raunin kwakwalwa. Asedara yawan tashin hankali, damuwa, canje-canje a cikin halaye, an lura da ci gaban baƙin ciki.
Yana da mahimmanci a fahimci cewa ya kamata a gudanar da insulin Isofan gwargwadon jadawalin da likitan ya tsara. Skipping allura yana tare da haɓakar mai ciwon sukari.
A cikin magungunan zamani, insulins na roba (na ɗan gajeren lokaci da na matsakaitan lokaci), analololo na hormone na mutum, kuma ana amfani da gaurayawan don sarrafa matakan glucose. Tabbas, kasuwar magunguna tana ba da magunguna da yawa waɗanda ke taimakawa na ɗan lokaci alamun bayyanar cututtukan sukari.
A cikin jerin analogues na iya hadawa da kwayoyi kamar “Actrafan”, “Biogulin”, “Diafan”. A wasu halaye, ana ba da shawarar marasa lafiya su dauki shirye-shiryen "Protafan", "Humodar", "Pensulin". Insulin Bazal da Fereyn suma ana ɗaukarsu masu kyau.
Ya kamata a fahimci cewa hormones manyan magunguna ne, kuma ba za ku iya amfani da su da kanku ba a kowane yanayi. Doctor ne kawai zai iya zaɓin analog kuma ya ƙayyade adadin.
Misali, kasancewar a kalla kari guda a cikin wani bayani a wasu marassa lafiya na iya haifar da gagarumar rashin lafiyar jiki har zuwa tashin hankalin anaphylactic.
Sauran bayanan hulɗa da magunguna
Kafin farawa magani, lallai ne ku sanar da likitanka game da magungunan da kuke shanwa. Ayyukan insulin na roba yana haɓaka yayin ɗaukar shi tare da sulfonamides, adrogen da steroids anabolic, MAO inhibitors, magungunan anti-mai kumburi marasa ƙarfi.
An bayyana tasirin hypoglycemic a kan asalin amfani da magungunan Isofan na lokaci guda tare da ketoconazole, cyclophosphamide, quinine, chloroquinine, quinidine, da kwayoyi masu dauke da lithium.
Af, ba a ba da shawarar sha barasa a lokacin da ake shan magani, tunda ethanol yana inganta tasirin insulin na roba.
Estrogens, maganin hana haihuwa, glucagon, heparin, hormones thyroid suna raunana tasirin maganin. Hakanan ana iya faɗi game da nicotine, marijuana, morphine, wasu diuretics (musamman, thiazide da madauki), maganin cututtukan tricyclic.
A kowane hali, ya kamata a fahimci cewa ba tare da sanin likita ba, ba za ku iya canza kashi ko jadawalin insulin ba. Bayyanar bayyanar da mummunan tashin hankali da rikicewar halayen yakamata a bayar da rahoton kai tsaye ga halartar endocrinologist.
Isofan insulin: umarnin don amfani da farashin miyagun ƙwayoyi
Harkokin insulin yana da halayyar maye, saboda babban aikin tiyata shine rama ga rashin damuwa a cikin ƙwayoyin carbohydrate ta hanyar gabatar da magani na musamman a ƙarƙashin fata. Irin wannan magani yana shafar jiki har da insulin na asali wanda ƙwayar ƙwayar ƙwayar cuta ta hanji. A wannan yanayin, magani cikakke ne ko kuma ɓangare.
Daga cikin magungunan da ake amfani da shi don kamuwa da cuta, ɗayan mafi kyawun shine insulin Isofan. Magungunan ya ƙunshi insulin asalin ɗan adam na matsakaici na tsawon lokaci.
Ana samun kayan aiki a fannoni daban-daban. Ana gudanar dashi ta hanyoyi guda uku - subcutaneously, intramuscularly da intravenously. Wannan yana bawa mai haƙuri damar zaɓin mafi kyawun zaɓi don sarrafa matakin glycemia.