Humulin® NPH (dakatarwa don gudanarwa a karkashin inuwar, 10 ml) insulin matsala (injiniyan ɗan adam)

Sashi da gudanarwa

S / c zuwa kafada, cinya, gindi ko ciki. An ba da izinin gudanar da intramuscular.

Ana amfani da matakin Humulin ® NPH ta likita daban-daban, gwargwadon yawan glucose a cikin jini. A / a cikin gabatarwar miyagun ƙwayoyi Humulin ® NPH yana contraindicated.

Zazzabi na miyagun ƙwayoyi da aka sarrafa ya kamata ya kasance da zazzabi a ɗakin. Dole ne a sauya wuraren allurar don kada a yi amfani da wurin iri ɗaya ba kusan sau ɗaya a wata ba. Tare da kulawar s / c na insulin, dole ne a kula da kar a shigar da jini. Bayan allurar, bai kamata a sanyaya wurin da allura ba.

Yakamata a horar da marassa lafiya yadda yakamata ayi amfani da na’urar insulin. Tsarin sarrafa insulin shine mutum ɗaya.

Shiri don gabatarwa

Don shirye-shiryen Humulin ® NPH a cikin vials. Nan da nan kafin a yi amfani da shi, ya kamata a yi birgima viulin ® NPH vials sau da yawa tsakanin murfin dabino har sai an sake yin insulin ɗin har ya zama daidai, ruwa mai narkewa ko madara. Shake da ƙarfi, kamar yadda wannan na iya haifar da kumfa, wanda zai iya tsoma baki tare da madaidaicin kashi. Kada kuyi amfani da insulin idan ya ƙunshi flakes bayan haɗuwa ko farin barbashi mai laushi da ke ƙasa ko ganuwar vial, yana haifar da sakamakon yanayin yanayin sanyi. Yi amfani da sirinji na insulin wanda ya dace da yawan insulin allura.

Don shirye-shiryen Humulin ® NPH a cikin katako. Nan da nan kafin amfani, Humulin ® NPH katunan ya kamata a birgima tsakanin tafin hannu sau 10 kuma girgiza, juya 180 ° kuma sau 10 har sai an sake samun insulin din har sai ya zama ruwan da aka sha ko madara. Shake da ƙarfi, kamar yadda wannan na iya haifar da kumfa, wanda zai iya tsoma baki tare da madaidaicin kashi. A cikin kowane katifa akwai ƙaramar ƙaramar gilashin da ke sauƙaƙe haɗuwa da insulin. Kina amfani da insulin idan yana dauke da flakes bayan an gauraya. Na'urar katuwar katako ba ta bada izinin haɗa abubuwan da ke cikin su tare da wasu abubuwan insulins kai tsaye a cikin katun da kanta. Ba a cika cika abubuwan alaƙar katako ba. Kafin allurar, ya wajaba don sanin kanka tare da umarnin mai ƙira don amfani da alkalami mai narkewa don gudanar da insulin.

Don Humulin ® NPH a cikin QuickPen ™ Syringe Pen. Kafin yin allura, ya kamata ka karanta QuickPen ™ Syringe Pen Umarnin don Amfani.

Jagorar Alƙawuri na QuickPen.

QuickPen ™ Syringe Pen yana da sauƙin amfani. Na'ura ce don gudanar da insulin (ƙarar insulin na insulin) wanda ke ɗauke da 3 ml (300 PIECES) na shirin insulin tare da aiki na 100 IU / ml. Kuna iya shiga daga raka'a insulin 1 zuwa 60 a allura. Zaka iya saita kashi tare da daidaitaccen raka'a ɗaya. Idan an kafa sassan da yawa, ana iya gyara kashi ba tare da asarar insulin ba. Ana bada shawarar QuickPen e Syringe Pen don amfani da allurar samarwa Becton, Dickinson da Kamfanin (BD) don alkairin sirinji. Kafin yin amfani da alkairin sirinji, tabbatar cewa allura ta kasance a haɗe da alkalami na syringe.

A nan gaba, yakamata a bi ƙa'idodin masu zuwa.

1. Bi dokokin asepsis da maganin antiseptics da likitanku ya ba ku.

3. Zaɓi wurin yin allura.

4. Shafa fata a wurin allurar.

5. Madadin wuraren allurar don kada a yi amfani da wurin iri ɗaya fiye da sau ɗaya a wata.

Shiri da Gabatarwa na QuickPen ™ Syringe Pen

1. capaga maɓallin murfin sirinji don cire shi. Kar a juya hula. Kar a cire tambarin daga alkalami na syringe. Tabbatar an bincika insulin don irin insulin, ranar karewa, bayyanar. A hankali mirgine sirinji sau 10 tsakanin tafin hannu kuma juya alƙawarin sau 10.

2. newauki sabon allura. Cire kwalin takarda daga saman kwalbar allura. Yi amfani da kayan maye wanda za a shafa diski na roba a ƙarshen abin riƙe da keken. Haɗa allura dake cikin hula, allally, zuwa alkalami na ƙwanƙwasa. Yi dunƙule akan allura har sai an haɗa shi cikakke.

3. Cire madancin daga allura. Kada ku jefa shi. Cire kwalban ciki na allura kuma ka watsar da shi.

4. Duba QuickPen ™ Syringe Pen don insulin. Kowane lokaci ya kamata ku bincika shan insulin. Tabbatar da isar da insulin daga alkairin sirinji yakamata a yi kafin kowane allura har sai tarin asulin ya bayyana don tabbatar da cewa alkalami na shirye don kashi.

Idan baka bincika cin insulin ba kafin tarkon ya bayyana, zaku iya samun insulin kadan ko yayi yawa.

5. Gyara fata ta cire shi ko tara ta a babban falo. Saka allurar sc ta amfani da allurar da likitan ka ya ba da shawarar ka. Sanya yatsan yatsa akan maɓallin kashi kuma latsa da tabbaci har sai ya daina gaba ɗaya. Don shigar da cikakken kashi, riƙe maɓallin kashi kuma sannu a hankali ƙidaya zuwa 5.

6. Cire allura kuma a hankali matsi wurin da allura ta auduga da auduga na da yawa na dan lokaci. Kar a shafa wurin allurar. Idan insulin ta sauka daga allura, wataƙila mara lafiya bai riƙe allurar a ƙarƙashin fata ya ishe shi ba. Kasancewar digo na insulin a saman allurar al'ada ce, ba za ta cutar da sashi ba.

7. Amfani da abin kaɗa allura, ɓoye allura kuma zubar dashi.

Hatta lambobi ana bugawa a taga alama kamar lamba, lambobi m azaman madaidaitan layi tsakanin lambobi.

Idan kashi da ake buƙata na aikin gwamnati ya wuce adadin raka'o'in da suka rage a cikin kicin, zaku iya shigar da ragowar insulin a cikin wannan alkairin sannan sai a yi amfani da sabon alkalami don kammala aikin da ake buƙata, ko shigar da duka kashi ta amfani da sabon sirinji na alkairin.

Kayi ƙoƙarin yin allurar ta hanyar jujjuya maɓallin kashi. Mai haƙuri ba zai sami insulin ba idan ya juya maɓallin kashi. Dole ne danna maɓallin sashi a cikin madaidaicin madaidaiciya don samun kashi na insulin.

Kada ayi ƙoƙarin canza sashin insulin yayin allurar.

Lura Alkalami na syringe ba zai ƙyale mai haƙuri ya sanya sashin insulin akan adadin adadin raka'o'in da suka rage cikin alkairin sirinji ba. Idan baku tabbata cewa ana aiwatar da cikakken maganin ba, to bai kamata ku shigar da wani ba. Ya kamata ku karanta kuma bi umarnin da ke kunshe a cikin umarnin don amfani da miyagun ƙwayoyi. Wajibi ne a duba lakabin a alƙalin sirinji kafin kowane allura, don tabbatar da cewa ƙarshen ranar magani bai ƙare ba kuma mai haƙuri yana amfani da nau'in insulin daidai, kar a cire alamar a cikin alkairin sirinji.

Launin launi na maɓallin maganin sirinji na QuickPick ™ wanda ya dace da launi na tsiri a kan alamar sirinji kuma ya dogara da nau'in insulin. A cikin wannan jagorar, an saka maɓallin kashi. Launin launi na QuickPen ™ syringe pen body yana nuna cewa an yi nufin amfani dashi tare da samfuran Humulin ®.

Adana da watsewa

Ba za a iya amfani da alkalami ba idan ya kasance a wajen firiji fiye da lokacin da aka ayyana a cikin umarnin don amfani.

Kar a ajiye alkairin sirinji tare da allura da aka haɗe da shi. Idan aka bar allura a haɗe, insulin na iya fita daga alƙalami, ko insulin na iya bushewa a cikin allura, ta haka ya rufe allura, ko kuma kumburin iska na iya tashi a cikin kicin.

Ya kamata a adana alkalamiin da ba a amfani da shi a firiji a zazzabi 2 zuwa 8 ° C. Kar a yi amfani da alkairin sirinji idan ya daskare.

Ya kamata a adana alkalami mai sihiri da aka yi amfani da shi a zazzabi a ɗakin a cikin wani wuri da aka kiyaye shi daga zafi da haske, daga isar yara.

Fitar da allura da aka yi amfani da su a cikin hujin huhu, kwantena masu kama da juna (alal misali, kwantena na abubuwan da ke tattare da abubuwa masu shaye shaye ko sharar gida), ko kuma yadda malamin lafiyar ku ya ba ku shawarar

Wajibi ne don cire allura bayan kowane allura.

Zubar da alkalami da aka yi amfani da shi ba tare da allura da aka haɗa da su ba da shawarar da likitan halartar yake da shi dangane da buƙatun zubar da shara na gida.

Kar a sake amfani da akwati mai cikar sharps.

Fom ɗin saki

Dakatarwa don gudanarwar subcutaneous, 100 IU / ml. 10 ml na miyagun ƙwayoyi a cikin tsinkayen gilashin tsaka tsaki. 1 fl. sanya a cikin fakitin kwali.

3 ml a cikin katakarar gilashin tsaka tsaki. 5 katunan katako an sanya su a cikin bolaji. 1 bl. an sanya su a cikin kwali kwali ko an saka katun a cikin allon rubutu na QuickPen ™. An sanya alkalai 5 a cikin kwali.

Mai masana'anta

An haɓaka ta: Eli Lilly da Kamfanin, Amurka. Cibiyar Lilly Corporate, Indianapolis, Indiana 46285, Amurka.

Kunshin: ZAO "ORTAT", 157092, Russia, yankin Kostroma, gundumar Susaninsky, s. Arewa, microdistrict. Kharitonovo.

Maɓallin shagon katako, QuickPen ens Sirrin Magana , Lilly Faransa, Faransa ne ya samar. Zone Industrialiel, 2 ru Colonel Lilly, 67640 Fegersheim, Faransa.

Kunshin: ZAO "ORTAT", 157092, Russia, yankin Kostroma, gundumar Susaninsky, s. Arewa, microdistrict. Kharitonovo.

Lilly Pharma LLC shine ke shigo da kaya na Humulin of NPH a cikin Federationungiyar Rasha.

Form sashi

Dakatarwa ga subcutaneous management na 100 IU / ml

1 ml na dakatarwa ya ƙunshi

abu mai aiki - insulin mutum (kwayar halittar DNA) 100 IU,

magabata: sodium hydrogen phosphate, glycerin (glycerol), phenol fluid, methacresol, protamine sulfate, zinc oxide, hydrochloric acid 10% don daidaita pH, sodium hydroxide 10% bayani don daidaita pH, ruwa don allura.

Wani farin dakatarwa, wanda, lokacin da yake tsaye, yakan bayyanar dashi cikin bayyananniyar, mara launi ko kusan madaukakiyar launi da farin fari. A sauƙaƙe za a sake tura shi cikin saurin girgiza kai.

Kayan magunguna

Pharmacokinetics

Humulin® NPH shiri ne na insulin-matsakaici.

Bayanan aikin insulin aiki na yau da kullun (na amfani da glucose) bayan allurar subcutaneous ana nuna su a cikin hoton da ke ƙasa kamar layin duhu. Bambancin da mai haƙuri zai iya fuskanta game da lokaci da / ko ofarfin aikin insulin a cikin adadi an nuna shi azaman yanki mai inuwa. Bambancin daidaikun mutane a cikin aiki da tsawon lokacin aikin insulin ya dogara da dalilai kamar kashi, zaɓin wurin allura, wadatar jini, zazzabi, aikin jiki na mai haƙuri, da dai sauransu.

Aikin insulin

Lokaci (awanni)

Pharmacodynamics

Humulin® NPH shine insulin kwayar halittar jikin ɗan adam.

Babban aikin Humulin® NPH shine tsari na metabolism metabolism. Bugu da ƙari, yana da tasirin anabolic da anti-catabolic akan ƙoshin jikin mutane daban-daban. A cikin ƙwayar tsoka, akwai karuwa a cikin abun da ke ciki na glycogen, kitse mai narkewa, glycerol, haɓakar haɓakar furotin da karuwa a cikin yawan amino acid, amma a lokaci guda akwai raguwa a cikin glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, catabolism na furotin da kuma sakin amino acid.

Side effects

yawan haila shine sakamako na yau da kullun da ke faruwa tare da gudanar da shirye-shiryen insulin, ciki har da Humulin® NPH.

Alamu m zuwa matsakaici hypoglycemia: ciwon kai, tsananin farin ciki, tashin hankali, bacci, bacci, bugun kirji, sanya damuwa a cikin hannaye, kafafu, lebe ko harshe, rawar jiki, damuwa, damuwa, hangen nesa, bayyanar mara izini, yanayi na bacin rai, tashin hankali, rashin iya maida hankali, halayen dabi'a, halayen canji , motsi mai girgiza, gumi, yunwar.

Alamu mai nauyi hypoglycemia: disorientation, rashin sani, rashi. A cikin lokuta na musamman, mummunan jini na iya haifar da mutuwa.

halayen rashin lafiyan gida (mita daga 1/100 zuwa 1/10) a cikin jan launi, kumburi, ko ƙaiƙayi a wurin allurar yawanci yakan tsaya a cikin kwanakin da yawa zuwa makonni da yawa. A wasu halaye, waɗannan halayen na iya lalacewa ta hanyar dalilan da basu da nasaba da insulin, alal misali, haushi na fata tare da wakilin tsarkakewa ko allurar da ba ta dace ba.

tsari halayen rashin lafiyan mutum (mita

Sashi da gudanarwa

Sashi na magani da yanayin gudanarwa yana ƙaddara ta likita daban-daban ga kowane mara lafiya, la'akari da tattarawar glucose a cikin jini.

An dakatar da zazzabi na daki ana gudanar da sc ko intramuscularly (an ba da izini), an hana contragrafiant gudanarwa.

Ana yin allurar ciki a cikin ciki, gindi, gwiwoyi ko kafadu, kar a kyale insulin ya shiga cikin jini. Bai kamata a yi amfani da wannan wurin allura sama da 1 a kowane wata ba (kamar). Bayan gudanar da magani, ba za a iya shayar da allurar wurin ba.

Kafin farawa likita, ya kamata a horar da mara lafiyar yadda yakamata a yi amfani da na'urar ta hanyar da za a gudanar da insulin.

Shiri don gudanar da magunguna

Kafin amfani, murfin tare da miyagun ƙwayoyi yana birgima sau da yawa tsakanin tafin hannayen, an yi birgima kwatancen sau 10 tsakanin tafin hannayen kuma yana girgiza, 10 sau ya juya 180 ° har sai an sake tayar da insulin kuma ya juya ya zama ruwan turjiya ko ruwa mai ruwa. Ba za a iya girgiza vial / kabad ba da ƙarfi sosai, saboda wannan na iya haifar da samar da kumfa, wanda hakan na iya tsoma baki tare da madaidaicin kashi.

Insulin, a cikin abin da ake lura da flakes bayan girgiza, ko a bango / kasan vial wanda aka kafa farar ƙasa mai ƙarfi, yana haifar da sakamakon yanayin yanayin sanyi, ba a amfani da shi.

Don gudanar da maganin daga vial, yi amfani da sirinji wanda ya dace da maida hankali na insulin da aka gudanar.

Kayan kayan aikin basu basu damar haxa maganin da sauran abubuwan insulins ba. Ba a cika cika abubuwan alaƙar katako ba.

Saurin Pen Syringe (injector) yana ba ku damar sarrafa raka'a 1-60 na insulin a allurar. Za'a iya saita sashi tare da daidaituwa na ɓangare ɗaya, idan an zaɓi kashi ɗin da ba daidai ba, ana iya gyara shi ba tare da rasa maganin ba.

Ya kamata mai haƙuri ɗaya ya yi amfani da shi, ƙaddamar da shi zuwa wasu mutane na iya zama matsayin watsa kamuwa da cuta. Ana amfani da sabon allura don kowane allura.

Ba ayi amfani da allurar ba idan wani ɓangaren sa ya lalace ko ya karye. Ya kamata mai haƙuri koyaushe ɗaukar takin sirinji na hutawa tare da shi saboda yiwuwar hasara ko lalacewar mai amfani.

Marasa lafiya marasa hangen nesa ko cikakkiyar hangen nesa ya kamata suyi amfani da allurar a ƙarƙashin jagorancin mutanen da suke gani da kyau waɗanda suka san yadda ake amfani da shi.

Kafin kowane allura, bincika lakabin akan alƙalin sirinji, wanda ya ƙunshi bayani game da ranar karewa da nau'in insulin. Injector din yana da maɓallin launin toka, launinsa ya dace da tsiri a jikin tambarin da nau'in insulin da aka yi amfani dashi.

Gudanar da magunguna

Ana amfani da allura don allurar insulin ta hanyar allura.Kafin amfani, yana da mahimmanci a tabbatar cewa allurar ta kasance cikakke a cikin allurar.

Lokacin da aka tsara insulin a cikin kashi wanda ya wuce raka'a 60, ana yin allura biyu.

A cikin yanayin inda mai haƙuri ba shi da tabbacin adadin magunguna da aka bari a cikin kicin, sai ya juya alƙalin yatsan tare da maɗaurin allura ya dube girman sikelin mai ɗaukar ma'amala, wanda ke nuna kimanin adadin insulin ɗin da ya ragu. Ba a yi amfani da waɗannan lambobin don saita kashi ba.

Idan mai haƙuri ba zai iya cire hula daga allura ba, yana buƙatar juya shi a hankali ta kowane irin agogo (a jere agogo), sannan ya ja shi.

Kowane lokaci kafin allura, bincika alkalami don insulin. Don yin wannan, cire maɗaukin allura na allura (ba a jefa shi ba), to sai filayen ciki (an jefa shi), juya maɓallin kashi har sai an saita raka'a 2, nuna mai injectionor ɗin kuma matsa kan mai riƙe katako don tara kumburin iska a cikin sashin na sama. Riƙe alkalami na syringe tare da allura, danna maɓallin kashi har sai ya tsaya kuma lambar 0 ta bayyana a cikin taga alama. Ci gaba da riƙe maɓallin kashi a cikin wurin da aka recessed, sannu a hankali ƙidaya zuwa 5. Idan akwai dunƙule na insulin a saman allura, ana ɗaukar gwajin an kammala kuma yayi nasara. A cikin yanayin inda tulin insulin bai bayyana a ƙarshen allura ba, ana maimaita matakan nema na karɓa 4 sau.

Umarnin don gudanar da miyagun ƙwayoyi ta amfani da injector:

• ana fitar da alkalami mai kaɗa daga kwalkwali,
• duba insulin
• newauki sabon allura, cire takarda mai suttura daga abin da ke a bayan sa,
• diski na roba a ƙarshen abin riƙe da katako ya goge shi da swab wanda aka tsoma shi a cikin giya,
• aka sa allurar ta kai tsaye ta gefen allurar har sai an haɗa ta gaba daya,
• duba insulin ci,
• ta amfani da maɓallin kashi suna saita adadin rakaɗin maganin,
• an saka allura a ƙarƙashin fata, tare da babban yatsa ya latsa maɓallin kashi har sai ya daina gaba ɗaya. Idan ya zama dole don gabatar da cikakken kashi - ana ci gaba da riƙe maɓallin kuma sannu a hankali ƙidaya zuwa 5,
• an cire allurar daga ƙarƙashin fata, an saka fila ta waje, an cire ta daga allurar kuma an zubar dashi daidai da umarnin likitan halartar,
• saka hula a aljihun syringe.

Kada a adana allura tare da allura da aka haɗa da su.

Idan mai haƙuri bai tabbata cewa ya ba da cikakken maganin ba, to, ba zai yi wani allura ba.

Umarni na musamman

Ana buƙatar tsananin kulawa na likita lokacin canza nau'in ko masana'anta na insulin. Bukatar daidaitawa na iya faruwa yayin canza alama, nau'in, aiki, nau'in halitta da (ko) hanyar samar da insulin.

Ana buƙatar buƙatar daidaita daidaituwa yayin canja wurin wasu marasa lafiya daga insulin na asalin dabba zuwa insulin ɗan adam - duka a lokacin farkon ƙarshen ƙarshen, kuma a hankali a cikin makonni da yawa ko watanni bayan fara amfani da shi. Ya kamata a ɗauka a cikin zuciya cewa a cikin wasu marasa lafiya, alamun bayyanar cututtuka na hypoglycemia tare da yin amfani da insulin na ɗan adam zai iya raguwa ko bambanta da waɗanda suka haɓaka tare da gabatarwar insulin na asalin dabba.

Wasu ko duk abubuwan da ke kokarin haifar da rashin karfin jini na iya lalacewa tare da daidaituwa na glucose na jini, alal misali, sakamakon magani mai zurfi tare da insulin. Ya kamata a sanar da marasa lafiya game da wannan a gaba.

A cikin batun jiyya tare da beta-blockers, diabetic neuropathy, dogon hanya na ciwon sukari mellitus, canji ko pronounasa da bayyanar alamun bayyanar cututtuka na hypoglycemia mai yiwuwa.

Ketoacidosis na ciwon sukari da hauhawar jini na iya haɓaka lokacin amfani da isasshen magunguna ko dakatar da magani.

Hepatic ko na koda, gazawar rashin lafiyar thyroid, glandon pituitary ko glandar adrenal na iya rage buƙatar insulin. Rstarfafawar Motsa jiki da wasu cututtuka, akasin haka, na iya ƙara buƙatar insulin. Lokacin canza yanayin abinci na yau da kullun ko kara yawan aiki na jiki, ana buƙatar daidaita sashi.

Yin amfani da haɗin magunguna na insulin tare da magungunan rukuni na thiazolidinedione yana ƙara haɗarin haɓakar bugun zuciya da edema, musamman tare da cututtuka na tsarin zuciya da gaban abubuwan haɗari don rauni na zuciya.

Sakamakon yiwuwar haɓakar hypoglycemia, marasa lafiya ya kamata suyi hankali a lokacin magani yayin injin aiki ko tuki motocin.

Hulɗa da ƙwayoyi

• turezide diuretics, sinadarin thyroid na thyroid, abubuwan da suka haifar da kwayoyin halittun phenothiazine, magunguna wadanda suke kara yawan glucose a cikin jini, nicotinic acid, glucocorticosteroids, maganin hana haihuwa, chlorprotixen, carbon lithium, beta-2-adrenergic agonists, danazol, isoniazid can,
• baka hypoglycemic kwayoyi, guanethidine, anabolic steroids, antagonists na angiotensin II rabe, angiotensin tana mayar enzyme hanawa, octreotide, sulfa maganin rigakafi, fenfluramine, wasu antidepressants (monoamine oxidase hanawa), tetracyclines, ethanol da etanolsoderzhaschie kwayoyi, beta-blockers, salicylates (acetyl salicylic acid da kuma kama. p.): na iya rage buƙatar insulin,
• reserpine, clonidine, beta-blockers: na iya rufe bayyanar cututtukan cututtukan cututtukan zuciya.

Misalin Humulin NPH sune Rosinsulin S, Rinsulin NPH, Protafan HM, Protamine-Insulin ChS, Insuman Bazal GT, Gensulin N, Vozulim-N, Biosulin.