Tresiba insulin: sake dubawa game da masu ciwon sukari game da maganin

wani tabbacin hypoglycemia wani lamari ne na hypoglycemia, wanda aka tabbatar dashi ta hanyar auna karfin glucose na jini b Abubuwa na hypoglycemia bayan mako na 16 na maganin Babu wani ingantaccen tsarin samarda kwayoyin zuwa insulin bayan magani tare da Tresiba Penfill ® na tsawan lokaci.

Pharmacokinetics

Baƙon
Babban aikin insulin degludec yana faruwa ne saboda tsarin halittar da aka sanya shi ta musamman. Bayan allurar subcutaneous, an samar da narkewar narkewar abinci mai narkewa wanda ke haifar da tarin iskar insulin a cikin ƙananan ƙwayoyin tsohuwar ƙwaƙwalwar ƙasa. Hean adam da yawa suna rarrabewa, suna sakin tsofaffin insulin na insulin, wanda ke haifar da jinkirin da ƙwayar magunguna cikin jini.
An daidaita daidaituwar ƙwayar magungunan Tresiba a cikin jini na plasma ana samun kwanaki 2-3 bayan gudanar da maganin.
Aikin insulin degludec na tsawon awanni 24 tare da gudanar da aikinta sau daya a rana ana rabawa a tsakanin sa'oi na farko da na biyu 12 (AUC)_{GIR, 0-12h, SS} / Auc_{GIR, T, SS} = 0,5).

Rarraba
Haɗin insulin degludec tare da ƙwayoyin plasma (albumin) shine> 99%.

Tsarin rayuwa
Rushewar insulin degludec yana kama da na insulin na mutum, duk metabolites da aka kafa basa aiki.

Kiwo
Rabin rayuwar bayan allurar subcutaneous na miyagun ƙwayoyi Tresiba ® Penfill ® an ƙaddara shi da ƙimar sha daga ƙwaƙwalwar subcutaneous.
Rabin rayuwar miyagun ƙwayoyi Tresiba ® Penfill ® kimanin sa'o'i 25 ne kuma baya dogaro da maganin.

Rashin layi
Tare da gudanarwa na subcutaneous, jimlar yawan plasma sun kasance daidai gwargwado ga adadin da aka gudanar a cikin kewayon allurai na warkewa.

Groupsungiyoyin haƙuri na musamman
Babu bambance-bambance a cikin kundin magungunan Tresiba ® Penfill drug dangane da jinsi na marasa lafiya.

Tsofaffi marasa lafiya, marasa lafiya na kabilu daban-daban, marasa lafiya da ke fama da rauni ko aikin hepatic
Ba a sami bambance-bambance mai mahimmanci na asibiti ba a cikin magungunan magunguna na insulin degludec tsakanin tsofaffi da matasa marasa lafiya, tsakanin marasa lafiya na kabilu daban-daban, tsakanin marasa lafiya da ke fama da rauni na aiki da aikin hepatic, da kuma marasa lafiya masu lafiya.

Yara da matasa
Abubuwan da ke cikin pharmacookinetic na insulin degludec a cikin wani binciken a cikin yara (shekaru 6-11) da matasa (12-18 years old) tare da nau'in ciwon sukari na 1 na mellitus sun yi daidai da waɗanda ke cikin majinyata na manya. Gabanin tushen tsarin magani guda ɗaya ga marasa lafiya da ke fama da cutar sukari ta 1 na 1, an nuna cewa ƙimar yawan maganin a cikin yara da matasa sun fi yadda a cikin majinyata na manya.

Karatun Tsaro na Lafiya

Bayanai na asibiti wanda aka danganta da nazarin lafiyar lafiyar masana’antar, guba na maimaituwar allurai, yuwuwar cutar carcinogenic, tasirin mai guba kan aikin haifuwa, bai bayyana wani hatsarin insulin degludec ga mutane ba.

Yi amfani yayin ciki da shayarwa

Amfani da miyagun ƙwayoyi Tresiba ® Penfill ® yayin daukar ciki an saba, tunda babu ƙwarewar asibiti tare da amfani dashi yayin daukar ciki.
Nazarin aikin dabbobi na dabbobi bai bayyana bambance-bambance tsakanin insulin degludec da insulin na mutum dangane da haihuwa da teratogenicity.

Lokacin shayarwa

Amfani da miyagun ƙwayoyi Tresiba ® Penfill ® yayin shayarwa yana da rauni, tunda babu ƙwarewar asibiti tare da amfani da ita a cikin matan masu shayarwa.
Nazarin dabbobi sun nuna cewa a cikin beraye, insulin degludec yana kwance a cikin madarar nono, kuma yawan ƙwayar magani a cikin madara nono ya ƙasa da na jini.
Ba'a sani ba ko insulin degludec an keɓance shi cikin madara mata.

Haihuwa

Nazarin dabbobi ba su sami sakamako masu illa na degludec insulin akan haihuwa ba.

Sashi da gudanarwa

Kashi na farko na maganin Tresiba ® Penfill ®

Nau'in marassa lafiya na guda 2
Thewarin da aka bayar da shawarar farko na Tresiba Penfill ® shine raka'a 10, sannan kuma zaɓi na kowane ƙwayar magani.

Nau'in Marasa lafiya na 1
Magungunan Tresiba ® Penfill ® an wajabta shi sau ɗaya a rana tare da insulin paldial insulin, wanda aka sarrafa shi da abinci, tare da zaɓi na kowane ƙwayar maganin.

Canja wuri daga sauran shirye-shiryen insulin
Kulawa da hankali game da tattarawar glucose na jini yayin canja wuri kuma a farkon makonni na sabon magani ana bada shawara.Zai yiwu a gyara halin rashin lafiya da ake amfani da shi (kashi da lokacin gudanar da gajeren insulin da insulin shirye-shiryen insulin ko kuma kashi na PHGP) na iya zama dole.

Nau'in marassa lafiya na guda 2
Lokacin canja wurin zuwa Tresiba ® Penfill ® shirye-shiryen marasa lafiya da ke da nau'in ciwon sukari na 2 na basir wanda ke kan lafiyar basal ko basal-bolus na insulin therapy, ko kan tsarin kulawa tare da abubuwan hadewar insulin / hadewar kai-kanka, kashi na Tresiba ® Penfill ® ya kamata a lissafta gwargwadon yawan insulin basal , wanda mai haƙuri ya karɓa kafin canja wuri zuwa sabon nau'in insulin, bisa ga ka'idar "ɓangare ɗaya ɗaya", sannan kuma ya daidaita daidai da bukatun mutum na haƙuri.

Nau'in Marasa lafiya na 1
A cikin mafi yawan marasa lafiya da ke da nau'in ciwon sukari na 1 na mellitus, lokacin da ake canzawa daga kowane insulin basal zuwa Tresiba Penfill ®, ana amfani da ka’idar-na-naúrar gwargwadon kashi na insulin basal wanda mai haƙuri ya karɓa kafin miƙa mulki, sannan ana daidaita sashi gwargwadon bukatun mutum. A cikin marasa lafiya da ke dauke da nau'in 1 na ciwon sukari mellitus, waɗanda a lokacin canja wuri zuwa far tare da Tresiba ® Penfill ® suna kan ilimin insulin tare da insulin basal a cikin tsarin kulawa na yau da kullum sau biyu, ko a cikin marasa lafiya da HbA_1CPenfill ® dole ne a sanya shi a kan aikin mutum. Wataƙila kuna buƙatar raguwa na kashi da keɓaɓɓen zaɓi na mutum dangane da alamun glycemia.

Tsarin allurai mai sauyawa
Dangane da bukatun mai haƙuri, maganin Tresiba ® Penfill ® yana ba ku damar canza lokacin gudanarwarsa (duba sashin ƙananan magunguna na Pharmacodynamics). A wannan halin, tazara tsakanin injections ya zama akalla 8 hours.
An ba da shawarar cewa waɗanda ke cikin marasa lafiyar da suka manta da bayar da maganin insulin cikin hanzari su shiga kashi da zarar sun samo shi, sannan kuma su koma lokacinsu na yau da kullun don gudanar da maganin yau da kullun.

Groupsungiyoyin haƙuri na musamman

Tsofaffi mara lafiya (fiye da 65 shekara)
Za a iya amfani da T karaba ® Penfill ® a cikin tsofaffi marasa lafiya. Ya kamata a kula da yawan glucose na jini a hankali kuma a daidaita sashin insulin din daban-daban (duba sashen Magunguna).

Marasa lafiya tare da nakasa koda kuma aikin hepatic
Ana iya amfani da Tresiba ® Penfill in a cikin marasa lafiya da ke fama da rauni na koda da aikin hepatic. Ya kamata a kula da yawan glucose na jini a hankali kuma a daidaita sashin insulin din daban-daban (duba sashen Magunguna).

Yara da matasa
An gabatar da bayanan data kasance game da magunguna na likitancin, duk da haka, ingancin da amincin Tresiba Penfill ® a cikin yara da matasa ba a yi nazarin ba, kuma ba a ci gaba da shawarwari game da yawan maganin a cikin yara ba.

Hanyar aikace-aikace
Tresiba ® Penfill ® an yi shi ne don gudanar da subcutaneous kawai. Ba za a iya gudanar da magungunan Tresiba ® Penfill ® ba cikin ciki, saboda wannan na iya haifar da matsanancin rashin ƙarfi. Tresiba ®
Ba za a iya gudanar da Penfill ® ba a cikin intramuscularly, tunda a wannan yanayin ɗaukar magungunan canji. Ba za a iya amfani da Tresiba ® Penfill in a cikin famfunan insulin.
Ana amfani da Tresiba ® Penfill ® subcutaneously a cinya, bangon ciki ko a kafada. Ya kamata a canza wuraren allurar koyaushe a cikin wannan yanki na jiki don rage haɗarin lipodystrophy. An tsara kayan kwalliyar Penfill ® don amfani da NovoFine ® ko NovoTvist ® allurar amfani da allura guda daya da kuma tsarin isar da insulin.

Yaushe ake amfani da Treshiba?

Babban alamu don fara amfani da miyagun ƙwayoyi sune sukari mara jini da kuma ƙarancin lafiya. Irin waɗannan bayyanar cututtuka na iya faruwa duka kan matsakaita da tsufa. Cutar ita ce zargi - ciwon sukari.

Dangane da fifiko da kuma saukin kamuwa da jiki ga wannan magani, kwararru sun tsara wasu kwayoyi, a layi daya da Tresiba.

Magungunan da ke cikin tambaya an riga an yi shi don masu ciwon sukari tare da nau'in cuta na biyu, amma tare da bincike mai zurfi, tare da haɓaka kwayoyin, ana iya amfani da miyagun ƙwayoyi don nau'in farko.

Lokacin amfani da analog na Degludek, wanda ake kira Tresiba, ba a yarda tsalle-tsalle na tsawon awanni 24 ba. Amfani da wannan magani, likitoci na iya cimma sakamako mafi kyau, ƙananan matakan sukari yayin jiyya.

Don haka muhimmin aiki na marasa lafiya da yawa yana inganta. Mutane da yawa sun san cewa idan an kiyaye matakan sukari a babban matakin, to, kyallen da ke cikin gabobin ciki na iya wahala matsananciyar wahala, kuma wannan ya ƙunshi mummunan sakamako.

Babban bambanci daga wasu kwayoyi shine tasirinsa na tsawon lokaci. Wannan yana rage haɗarin hauhawar jini. Partananan ƙananan ƙwayoyi na maganin ba kusan bambance-bambance na musamman daga insulin ɗan adam ba. Hakanan sun sami damar haɗuwa cikin manyan kwayoyin, don haka suna riƙe ajiyar.

Tasirin yana faruwa kusan nan da nan bayan an sha maganin. Ta wata hanyar, yayin allurar, wani nau'in tara kayan ajiyar abubuwa a cikin marasa lafiya yana faruwa, kamar yadda ake buƙata, ana amfani dashi don rage sukari.

Side sakamako

Bayanin kowane mummunan tasirin cutar cututtukan tsarin cuta
Lokacin amfani da shirye-shiryen insulin, halayen rashin lafiyan na iya haɓaka. Allergic halayen da wani nan da nan ga insulin kansa da kanta ko ga kayan taimako wanda ke yin hakan na iya yin illa ga rayuwar mai haƙuri.
Lokacin amfani da miyagun ƙwayoyi Tresiba ® Penfill ®, maganganun rashin jin daɗi (gami da kumburin harshe ko lebe, zawo, tashin zuciya, gajiya da ƙoshin fata) da cutar urticaria sun kasance masu wuya.

Hypoglycemia
Hypoglycemia zai iya haɓaka idan kashi na insulin ya yi yawa sosai dangane da buƙatar haƙuri ga insulin. Mai tsananin rashin ƙarfi na iya haifar da asarar hankali da / ko raɗaɗi, wucin gadi ko maye gurbin ayyukan kwakwalwa, har ma da mutuwa. Bayyanar cututtuka na hypoglycemia, a matsayin mai mulkin, yana haɓaka ba zato ba tsammani. Wadannan sun hada da gumi mai sanyi, pallor na fata, gajiya mai yawa, juyayi ko rawar jiki, damuwa, gajiya mai yawa ko rauni, rashin damuwa, raguwar hankali, nutsuwa, matsananciyar yunwar gani, ciwon kai, ciwon kai, tashin zuciya, bugun zuciya.

Lipodystrophy
Lipodystrophy (gami da lipohypertrophy, lipoatrophy) na iya haɓaka a wurin allurar. Yarda da ka'idodi don sauya wurin allura a cikin yanki ɗaya na ƙwayar cuta yana taimakawa rage haɗarin ci gaba da wannan mummunar cutar.

Amsawa a wurin allurar
Marasa lafiya da aka yi wa Tresiba ® Penfill ® sun nuna halayen a wurin allurar (hematoma, jin zafi, basur a cikin gida, erythema, nohules na haɗi, kumburi, fitar da fata, ƙaiƙayi, haushi da matsi a wurin allurar). Yawancin halayen da ke faruwa a wurin allurar sunyi kankanta da ɗan lokaci kuma yawanci sun ɓace tare da ci gaba da magani.

Yara da matasa
An yi nazarin abubuwan da ke cikin Pharmacokinetic na miyagun ƙwayoyi Tresiba children Penfill in a cikin yara da matasa a cikin shekaru 18 (duba sashen Magunguna na Pharmacokinetics). Ba a gudanar da bincike kan tasiri da amincin insulin degludec a cikin yara da matasa ba.

Groupsungiyoyin haƙuri na musamman
A lokacin gwaji na asibiti, ba a sami bambance-bambance ba a cikin mitar, nau'in, ko tsananin raunin da ya faru tsakanin tsofaffi marasa lafiya da marasa lafiya da ke fama da rauni ko aikin hepatic da yawan haƙuri.

Ta yaya miyagun ƙwayoyi ke aiki?

Tushen magunguna shine abu mai aiki, wanda zai iya samun tasiri na musamman akan jiki, don haka yana canza adadin sukari a cikin jini. Babban abu yana aiki kamar Levemir, Lantus, Apidra da Novorapid. Treshiba insulin kusan analog ne na hormone mutum.

Idan aka kwatanta da insulin na halitta, Tresiba shine mafi inganci kuma ingantaccen magani. Kuma abin da ya fi muhimmanci shi ne cewa babu hani akan amfani, tunda abun da keɓaɓɓen insulin ya dace da kusan kowa.

Magungunan yana da tasiri sosai a jikin mai haƙuri, bisa ga ƙoƙarin masana kimiyya na zamani. An samu wannan sakamakon ta hanyar amfani da fasahar kere kere ta kankantar da halittu ta hanyar DNA tare da nau'ikan cerechaia na Saccharomyces. A lokaci guda, an yi gyare-gyare da yawa na tsarin kwayoyin.

A yau, waɗancan marasa lafiya waɗanda ke da nau'in cutar ta farko ko ta biyu na iya, ba tare da wata shakka ba, suna amfani da insulin na Treshiba don ragewa da sarrafa sukarin jininsu.

Fasalin aikin abun da ke ciki:

• Tasirin aikin miyagun ƙwayoyi shine cewa kwayoyin halitta suna iya haɗuwa cikin manyan kwayoyin. Wannan yana faruwa kusan kusan nan da nan bayan gabatarwar abun da ke ciki a fata. A cikin jikin, ana samar da abu kamar su deulin insulin. Yana taka rawar insulin na yau da kullun,
• Ana samun sakamako mai tsawo saboda ƙananan allurai - yafi tasiri fiye da insulin, wanda aka yi amfani dashi a baya.

Tresiba insulin din da kuma yadda ya dace

Ana amfani da miyagun ƙwayoyi ta musamman a ƙarƙashin fata, haramun ne a sarrafa shi a cikin jijiya. Game da yanayin gudanarwa, aiwatarwa yana gudana sau ɗaya tak a cikin kowane sa'o'i 24. Babu rikici tare da wasu kwayoyi sun faru. Ana amfani da insulin tare da magungunan kwayoyi waɗanda ake amfani da su don rage ƙananan sukari ko tare da wasu insulin.

An tsara Tresiba azaman magani mai zaman kanta ko a hade tare da wasu magunguna don cimma sakamako. Idan insulin da ke cikin tambayoyin ba a taɓa ba da shi ga masu ciwon sukari, kashi na farko ba zai wuce fannoni 10 ba. Bayan wannan, ana aiwatar da gyaran da ya dace, gwargwadon sakamakon da bukatun mutum.

A cikin abin da ya kasance an riga an wajabta wa mutum wani nau'in insulin, amma ana buƙatar canja wuri zuwa Treshiba, kashi na farko zai zama iri ɗaya. Daga baya, zaku iya yin gyare-gyare tare da likitoci.

Lokacin da mutumin da ke fama da ciwon sukari yayi amfani da tsarin kulawa na miyagun ƙwayoyi sau biyu ko a cikin marasa lafiya glycated haemoglobin yana cikin kewayon 8% ko lessasa, ana saita sashi daban. Yana faruwa cewa sashi ya rage. A kowane hali, yakamata a zaɓi sashi ta ƙwararrun masanan, yin la'akari da sakamako da kayan aikin mutum.

Tresiba insulin da amfanin sa

Ganin ƙididdigar likita na yanzu, Tresiba kusan ba ya haifar da hypoglycemia. Wannan an tabbatar da hakan ta hanyar dubawa da haƙuri da yawa.Idan kun bi duk shawarwarin likitoci da ka'idojin koyarwa, to babu raguwar sukari a cikin jini zai faru.

Karin magunguna na Tresiba:

• kadan hadarin glycemia yayin rana, idan aka kwatanta da sauran nau'in insulin,
• Ingancin ƙwayar Tresib ita ce cewa yawancin endocrinologists suna iya samun ingantaccen sashi, kowannensu ga kowane mai haƙuri.

Tare da taimakon Treshiba, zaku iya samun mafi kyawun ladabi don tafiyar matakai, wannan yana taimaka wajan inganta lafiyar marasa lafiya da sauri, yana sa ya zama mai tsayayye. Yana da kyau a lura cewa babu wasu sakamako masu illa da suka faru. Wannan an tabbatar da tabbatacce game da ra'ayoyin marasa lafiya.

Tresiba yana inganta lafiyar marasa lafiya da masu ciwon sukari

Yaya za a gudanar da maganin?

Daga abin da aka faɗa a sama, ana iya ƙaddara cewa an ƙulla maganin ne don gudanar da aikin subcutaneous tare da mita na 1 a kowace rana. Idan mai haƙuri bai taɓa yin sabon insulin ba, amma ya yi amfani da wani nau'in insulin, ana bada shawara don farawa tare da ƙarar da bai wuce 10 AZUMI ko'ina cikin yini.

Lokacin canzawa daga nau'in insulin zuwa sabon, yana da kyau a yi amfani da ƙaramin kashi, sannan a yi gyara don cimma sakamako mafi kyau.

Shin akwai wasu hasara ga insulin na Tresib?

Baya ga gaskiyar cewa wannan magani yana da fa'idodi masu yawa, rashin daidaito ma yana nan.

Abu na farko da ya kamata ka san shi shine rashin iya amfani da samfurin lokacin samartaka mai kyau. Hakanan haramun ne ga mata masu juna biyu da masu shayarwa. Rashin kyau shine ba za a iya amfani da Treshib a ciki ba.

An haramta shigo da miyagun ƙwayoyi ga mata masu juna biyu

Magunguna gabaɗaya sababi ne kuma, baya ga ingantaccen tasirin sa da fa'idarsa akan sauran nau'in insulin, maras lokaci. Zuwa yau, an sanya bege mai yawa ga sabon kayan aiki don sarrafawa da rage girman sukari na jini, amma ba a bayyana abin da zai faru ba a cikin shekaru 6-8, saboda akwai haɗarin kowane rikitarwa.

Yana da mahimmanci a lura cewa, kamar sauran magunguna, Tresiba na iya haifar da rashin lafiyan ƙwayar cuta, duk yana dogara ne akan halayen mutum na mutum. Idan hakan ta faru, to ba a bada shawarar kayan aikin ba.

Matsalolin da aka bayyana ta hanyar gaskiyar cewa maganin bai dace ba sun haɗa da bayyanannun bayyanannun:

• bayyanuwar tashin hankali anaphylactic,
• rashida farawa
• bayyanar cutar urticaria da alamu masu kama da juna,
• lipodystrophy,
• sauƙaƙawar ji na ɗabi'a a cikin ɗabi'ar itching ko kumburi,
• bayyanar nodules, bruises ko seals a farfajiyar fata.

Masu iya gasa

Babban dan takarar Treshiba shine Lantus. Ana kuma sarrafa wannan nau'in insulin sau ɗaya a rana kuma yana da tasiri. Dangane da sakamakon bincike na asibiti tsakanin magungunan biyu, an tabbatar da cewa insulin Tresiba da Lantus suna iya daidaita aikin daidaita matakan sukari na jini.

Amma har yanzu akwai bambance-bambance tsakanin magungunan guda biyu. Lokacin amfani da Treshiba, ana rage sashi zuwa kusan 20-25%. A takaice dai, yana da fa'ida ta tattalin arziki.

Takaitawa

Rufewar sukari da daddare - wannan shine mafi munin wahayi na masu ciwon sukari. Kuma idan babu tsarin sa ido, to kawai roko ga kwararru ne ke taimakawa. A saboda wannan dalili, ana bada shawara cewa kayi tunani game da kwanciyar hankali na kwanciyar hankali ta amfani da magunguna da aka tabbatar.

Yakamata likitoci suyi aiki da zabinsu, la'akari da yawancin halaye na jikin mutum.

Halaye da kaddarorin insulin Tresiba

Ana amfani da insulins masu aiki da tsayi don ɗaukar adadin hormone a cikin nau'in 1 da nau'in ciwon sukari na 2. Wadannan magungunan sun hada da Tresiba wanda Novo Nordisk kera.

Tresiba magani ne wanda ya danganta da sinadarin hormone na babban aiki.

Wani sabon analog ne na insulin basal.Yana bayar da guda daya na glycemic iko tare da rage hadarin cututtukan cututtukan ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa.

Siffofin maganin sun hada da:

• barga kuma mai santsi raguwa a cikin sukari,
• sama da awa 42
• low bambanci
• ci mai sukari,
• ingantaccen bayanin martaba
• yuwuwar canji kadan a lokacin gudanar da insulin ba tare da cutar da cutarwa ba.

Ana samar da magungunan a cikin hanyar katukan katako - "Tresiba Penfil" da sirinji-alkalami, wanda a ciki aka rufe katunan, "Tresiba Flexstach". Abubuwan da ke aiki shine insulin Degludec.

Degludek yana ɗaure bayan gudanarwa zuwa kitse da ƙwayoyin tsoka. Akwai jan hankali da ci gaba a cikin jini. Sakamakon haka, ana samun ci gaba a cikin sukarin jini.

Magungunan yana inganta sha daga glucose ta kyallen da ke hana sirrinta hanta. Tare da kara sashi, ragewar sukari yana ƙaruwa.

An samar da daidaituwa na kwayar halitta a cikin matsakaici bayan kwana biyu na amfani. Abun da ake buƙata shine ya shafe fiye da awanni 42. Cire rabin rayuwa yana faruwa a cikin rana.

Alamu don amfani: nau'in 1 da 2 na ciwon sukari a cikin manya, ciwon sukari a cikin yara daga shekara 1.

Contraindications don ɗaukar insulin na Tresib: rashin lafiyan kayan haɗin magunguna, rashin haƙuri na Degludek.

Umarnin don amfani

Ana amfani da maganin sosai a lokaci guda. Yanzun nan ana samun karbuwa a rana. Marasa lafiya tare da nau'in ciwon sukari na 1 suna amfani da Degludek a hade tare da gajeren insulins don hana shi buƙata yayin abinci.

Marasa lafiya tare da ciwon sukari suna ɗaukar magani ba tare da ambaton ƙarin magani ba. Ana amfani da Tresiba duka daban kuma a hade tare da magungunan tableted ko wasu insulin. Duk da sassauci a cikin zaɓar lokacin gudanarwa, mafi ƙarancin tazara ya zama aƙalla 8 hours.

Likita ne ya saita sashi na insulin. An ƙididdige shi gwargwadon bukatun mai haƙuri a cikin hormone tare da ambaton amsawar glycemic. Yawan shawarar da aka bada shawarar shine raka'a 10. Tare da canje-canje a cikin abincin, lodi, ana aiwatar da gyaran sa. Idan mai haƙuri da masu ciwon sukari na 1 ya ɗauki insulin sau biyu a rana, adadin insulin da aka gudanar ana tantance shi daban-daban.

Lokacin canzawa zuwa insulin na Tresib, yawan sarrafa glucose ana sarrafa shi sosai. An kula da musamman don alamomi a farkon satin fassara. Ana amfani da kashi ɗaya zuwa ɗaya daga sashi na baya na miyagun ƙwayoyi.

Tresiba yana allurar subcutaneously a cikin wadannan fannoni: cinya, kafada, bangon gaban ciki na ciki. Don hana haɓaka haushi da ƙoshinsa, wurin ya canza sosai a cikin yankin.

An hana shi gudanar da kwayoyin cikin ciki. Wannan yana tsoratar da ƙwanƙwasawar jini. Ba'a amfani da maganin a cikin farashin jiko da intramuscularly. Maniarshen amfani na iya canza ƙimar sha.

Mahimmanci! Kafin amfani da alkairin sirinji, ana aiwatar da umarnin, ana yin nazarin umarnin a hankali.

Umarni na bidiyo akan amfani da alkairin sirinji:

Side effects da yawan abin sama da ya kamata

Daga cikin raunin da aka samu a marasa lafiya da ke shan Tresiba, an lura da masu zuwa:

• hypoglycemia - sau da yawa
• lipodystrophy,
• na gefe harshe,
• halayen rashin lafiyan fata
• halayen a wuraren allura,
• ci gaba na retinopathy.

A lokacin aiwatar da shan miyagun ƙwayoyi, hypoglycemia na tsananin tsananin na iya faruwa. Ana ɗaukar matakai daban-daban dangane da yanayin.

Tare da raguwa kaɗan a cikin glycemia, mai haƙuri yana cin 20 g na sukari ko samfura tare da abubuwan da ke ciki. An ba da shawarar cewa koyaushe kuna ɗaukar glucose a cikin adadin da ya dace.

A cikin yanayi mai tsanani, wanda ke tattare da asarar hankali, an gabatar da IM glucagon. A cikin yanayin da ba canzawa, an gabatar da glucose. Ana kula da haƙuri ga sa'o'i da yawa. Don kawar da koma baya, mai haƙuri yana ɗaukar abincin carbohydrate.

Marasa lafiya na musamman da kuma Jagorori

Bayanai game da shan maganin a cikin rukuni na musamman na marasa lafiya:

1. An yarda da Tresiba don tsofaffi suyi amfani da shi. Wannan rukuni na marasa lafiya ya kamata kula da matakan sukari akai-akai.
2. Babu karatuttuka kan tasirin maganin yayin daukar ciki. Idan an yanke shawarar shan magungunan, ana ba da shawarar inganta haɓaka abubuwan da ke nuna alamomi, musamman a cikin karo na 2 da na uku.
3. Har ila yau, babu bayanai game da tasirin maganin yayin lactation. Yayin aiwatar da ciyar da jarirai, ba a lura da munanan halayen ba.

Lokacin ɗauka, ana ɗaukar haɗarin Degludek tare da wasu kwayoyi.

Anabolic steroids, ACE inhibitors, sulfonamides, adrenergic blockers, salicylates, magungunan rage karfin tebur, masu hana MAO suna rage matakan sukari.

Magungunan da ke kara buƙatar homon sun haɗa da juyayi, glucocorticosteroids, Danazole.

Barasa na iya shafar aikin Degludek duka a cikin shugabanci na haɓaka da rage ayyukansa. Tare da haɗuwa na Tresib da Pioglitazone, gazawar zuciya, kumburi na iya haɓaka. Marasa lafiya suna ƙarƙashin kulawar likita yayin jiyya. Game da aiki mai rauni na aikin zuciya, an dakatar da maganin.

A cikin cututtukan hanta da kodan yayin jiyya tare da insulin, ana buƙatar zaɓin kowane mutum. Marasa lafiya yakamata su sarrafa sukari sau da yawa. A cikin cututtukan cututtuka, cututtukan thyroid, damuwa na jijiya, buƙatar canji mai mahimmanci don canzawa.

Mahimmanci! Ba za ku iya canza sashi ba da izinin zama ko soke maganin don hana hypoglycemia. Likita ne kawai ya tsara maganin kuma ya nuna alamun aikinta.

Magunguna tare da irin wannan sakamako, amma tare da wani sashi na daban mai aiki, sun hada da Aylar, Lantus, Tujeo (insulin Glargin) da Levemir (insulin Detemir).

A cikin gwaje-gwajen gwaje-gwaje na Tresib da kwayoyi masu kama, an ƙaddara yin aiki ɗaya. A yayin binciken, an sami karancin yawan zafin jiki kwatsam, na karancin jinin haila.

Shaidun masu ciwon sukari suma suna bayar da hujjoji na inganci da amincin Treshiba. Mutane sun lura da ingantaccen aikin da amincin miyagun ƙwayoyi. Daga cikin rashin damuwa shine babban farashin Degludek.

Tresiba magani ne wanda ke samar da asaline na insulin. Yana da kyakkyawan bayanin martaba kuma yana rage sukari daidai. Nazarin haƙuri yana tabbatar da inganci da kwanciyar hankali. Farashin insulin na Tresib kusan 6000 rubles ne.

Muna bada shawara ga wasu labaran masu alaƙa

Tresiba - Tresiba Reviews

Tresiba magani ne na insulin wanda ake amfani dashi don kamuwa da cutar siga. Magungunan mai aiki mai amfani da wannan ƙwayar cuta an samar da shi ta hanyoyin kimiyyar ilimin zamani - cikakkiyar analog ne na insulin ɗan adam.

A cikin rarrabuwar magungunan masu ciwon sukari gwargwadon saurin farawa da tsawon lokacin tasirin, Tresib yana nufin masu wuce gona da iri.

Ta wata hanyar, bayan dosing, sashin ƙwayar da ke aiki yana ɗaure wa masu karɓar insulin kuma yana haifar da raguwa na dogon lokaci a cikin glucose a cikin jinin haƙuri.

Ana amfani dashi lokacin da:

• Nau'in 1 da nau'in ciwon sukari na 2 a cikin manya tare da halayen m zuwa insulin,

Tresib an samar dashi ta hanyar samarda mafita a cikin katukan katako wanda ake amfani da shi azaman tsarin allura - wanda ake kira "alkalami". Ana yin allurar kawai subcutaneously - cikin fatar fatar kan cinya, kafada ko ciki. Idan ana gudanar da wannan wakili a cikin zuciya, mutum zai sami hauhawar jini, wanda zai shafi lafiyar duk gabobin da tsarin, kuma zai iya haifar da komputa.

Koyarwar miyagun ƙwayoyi Tresiba ta ba da rahoton cewa ya kamata a sanya shi sau ɗaya a rana. Don wannan, an zaɓi lokacin mafi kyau, wanda za'a bi lokacin gudanar da magani. Idan mara lafiya ya rasa lokacin allura, to lallai ya zama dole a cika wannan rata da wuri-wuri, sannan a koma cikin tsarin da aka saba.

Kamar kowane hanya da ke sarrafa sukari na jini, ana amfani da maganin kwalliya ta hanyar glucometer. Ana iya amfani da wannan magani daban kuma a hade tare da sauran magungunan hypoglycemic.Lokacin maye gurbin wasu kudade tare da Tresib, yana da muhimmanci a sake tara kashi ɗin. Anan, a matsayinka na doka, ana amfani da tsarin ƙididdige-naúrar.

Idan zaka fara amfani da wannan magani a karon farko, karanta umarnin don shirya “sirinji” kuma ka bi dukkan ka'idodi don magance shi.

An sanyawa cikin:

• Haihuwa da lactation
• Kulawa da marassa lafiya yan kasa da shekaru 18,
• Rashin yarda da miyagun ƙwayoyi,

Side effects da yawan abin sama da ya kamata

Ana tsammanin cewa mafi yawan lokuta a cikin marasa lafiya da ke amfani da shirye-shiryen insulin, yanayi mai zuwa yana faruwa:

• hypoglycemia - raguwar wuce kima a cikin taro na glucose a cikin jini,
• ko hyperglycemia - haɓakar taro a cikin glucose sama da yanayin (misali, tare da isasshen kashi na insulin),

Hakanan, marasa lafiya sau da yawa suna korafi cewa halayen da ba a so ba suna faruwa a wurin allurar - compaction, bruising, irritation, da sauransu.

Idan baku musanya wurin allurar ba, lafiyar ƙashin bayan kashi yana iya wahala tare da haɓakar lipodystrophy (lalata tsohuwar nama).

Hypoglycemia shima babban hatsari ne idan ana yawan samun Tresib. Tare da raguwa kaɗan na sukari, mai haƙuri zai iya rama shi ta hanyar cin alewa, ɗan sukari. Amma a lokuta masu wahala, tare da asarar hankali - gabatarwar shirye-shiryen glucose ya zama dole.

Analogs suna da rahusa fiye da Tresib

Wannan magani ba shi da alamun analogues kai tsaye. Amma kantin magani yana ba da kudade masu yawa dangane da insulin. Misali:

• Lantus
• Levemir,
• Gensulin
• Biosulin
• Ribar insulin
• Aiki

Kusan dukkanin su suna da rahusa fiye da Tresib. Amma a nan yana da mahimmanci ba farashin ba, amma halayen mutum na jikin mai haƙuri zuwa hanyoyi daban-daban. A kansu ne likitan ya samo asali, yana tsara wasu magunguna don rage sukarin jini. Haka kuma, da yawa daga cikinsu ana baiwa marassa lafiya gwargwadon magunguna.

Tresiba insulin-dogon-fasali na aikace-aikace da lissafin sashi

Tresiba shine mafi dadewa insulin basal da aka yiwa rajista har zuwa yau. Da farko, an kirkira shi ne ga marasa lafiya waɗanda har yanzu suna da nasu ƙwayar insulin, wato, don kamuwa da cutar siga 2. Yanzu an tabbatar da ingancin magungunan ga masu ciwon sukari masu cutar cuta ta 1.

Tresibu an samar da shi ta hanyar sanannen damuwar Danish NovoNordisk. Hakanan, samfuransa sune Actrapid na gargajiya da Protafan, sababbi ne na sabon analogues na insulin Levemir da NovoRapid.

Masu ciwon sukari tare da gwaninta suna da'awar cewa Treshiba ba ta da ƙaranci ga magabata - Protafan na matsakaiciyar tsawon lokacin aiki da tsawon Levemir, kuma dangane da kwanciyar hankali da daidaituwa na aiki ya wuce su.

Ka'idar Treshiba

Don masu ciwon sukari nau'in 1, sake maye gurbin insulin da ya ɓace ta allurar hormone na wucin gadi yana da izini. Tare da nau'in ciwon sukari na 2 mai tsawo, ilimin insulin shine mafi inganci, da sauƙin haƙuri da magani mai tsada. Onlyayan abu mafi lalacewa kawai na shirye-shiryen insulin shine haɗarin haɗarin hauhawar jini.

Sannu Sunana Galina kuma ba na samun ciwon suga! Na ɗauki makonni 3 kacaldon dawo da sukari zuwa al'ada kuma kar a kamu da shi da kwayoyi marasa amfani
>> Kuna iya karanta labarina a nan.

Faduwa sukari yana da haɗari musamman da daddare, saboda ana iya gano latti, saboda haka buƙatun aminci na dogon insulins suna girma koyaushe A cikin ciwon sukari na mellitus, mafi tsayi da kwanciyar hankali, mara ƙarancin tasirin magungunan, ƙananan haɗarin hauhawar jini bayan gudanarwarsa.

Insulin Tresiba ya cika burin:

1. Magungunan yana cikin sabon rukuni na insulins na dogon lokaci, tunda yana aiki fiye da sauran, sa'o'i 42 ko fiye. Wannan ya faru ne saboda gaskiyar cewa kwayoyin halittun da aka gyara sun “manne tare” a karkashin fata kuma an sake su cikin jini a hankali.
2. Awanni 24 na farko, maganin yana shiga jini daidai, to kuwa sakamakon yana raguwa sosai.Kololuwar aiki gaba daya ba ya nan, bayanin martaba ya kusan lebur.
3. Duk allura suna aiki iri ɗaya. Kuna iya tabbata cewa ƙwayar zata yi aiki daidai kamar jiya. Sakamakon adadin allurai daidai yake a cikin marasa lafiya na shekaru daban-daban. Bambancin aiki a Tresiba sau 4 ƙasa da na Lantus.
4. Tresiba yana tsokanar cutar kashi 36 cikin dari fiye da dogon lokacin insulin analogues a cikin lokaci daga 0:00 zuwa 6:00 awanni tare da ciwon sukari na 2. Tare da nau'in cuta ta 1, amfanin ba a bayyane yake ba, ƙwayar ta rage haɗarin rashin jini a cikin maraba da kashi 17%, amma yana ƙaruwa da haɗarin rashin lafiyar rana da kashi 10%.

Abubuwan da ke aiki da Tresiba shine degludec (a wasu hanyoyin - degludec, Ingilishi degludec). Wannan insulin din ne dan adam yake canzawa, wanda a cikinsa ake canza tsarin kwayoyin. Kamar hormone na halitta, yana da ikon ɗaure wa masu karɓar sel, yana inganta yanayin sukari daga jini zuwa kyallen, kuma yana rage jinkirin samar da glucose a cikin hanta.

Da amfani Yana da matukar muhimmanci a rarrabe tsakanin nau'ikan insulin, don fahimtar tasirin su da bambance-bambance. Idan baku san yadda ake yin wannan ba, tabbatar da karanta wannan labarin.

Sakamakon tsarin da aka canza shi, wannan insulin din yana da yiwuwa ya samar da hadaddun hexamers a cikin kayan. Bayan gabatarwa a karkashin fata, yana samar da wani nau'in depot, wanda aka sha a hankali kuma a cikin tsawan lokaci, wanda ke tabbatar da samar da kwayar halittar hormone a cikin jini.

Daga ra'ayi na ilimin kimiyyar lissafi, tare da ciwon sukari, Tresiba ya fi sauran insulin basal maimaita sakewa na halitta na hormone.

Fom ɗin saki

Ana amfani da maganin a cikin siffofin 3:

1. Tashanba Penfill - katuwar katako tare da mafita, maida hankali kan kwayar halittar a cikinsu ta zama daidaitacce - U za a iya buga insulin tare da sirinji ko saka harsashi cikin allonn NovoPen da makamantansu.
2. Tresiba FlexTouch tare da maida hankali akan U100 - alkalami mai sirinji wanda aka ɗora kwandon shara 3 ml. Ana iya amfani da alkalami har sai insulin da ke ciki ya kare. Ba a bayar da sauyawa Cartridge. Matakan sashi - guda ɗaya, kashi mafi girma don gabatarwar 1 - raka'a 80.
3. Tresiba FlexTouch U200 - wanda aka kirkira don saduwa da ƙaruwar ƙwayar jijiyoyin jiki, yawanci waɗannan sune marasa lafiya tare da ciwon sukari mellitus tare da juriya na insulin mai ƙarfi. Darfafa yawan insulin ya ninka sau biyu, don haka ƙarar mafita da aka gabatar da fata ba ta da ƙasa. Tare da sirinji na syringe, zaku iya shigar da sau ɗaya zuwa raka'a 160. hormone a karuwa of raka'a 2. Cartridges tare da babban taro na degludec Babu matsala zaka iya fita daga almarar sirinji na asali ka saka cikin wasu, kamar yadda wannan zai haifar da yawan yawan zubar jini da hauhawar jini.

A cikin Rasha, dukkanin nau'ikan magungunan 3 suna rajista, amma a cikin kantunan magunguna suna ba da yawancin Tresib FlexTouch na maida hankali ne na yau da kullun. Farashin Treshiba ya fi na sauran tsayi. Shirya tare da sikelin 5 5 (15 ml, raka'a 4500) farashi daga 7300 zuwa 8400 rubles.

Baya ga degludec, Tresiba ya ƙunshi glycerol, metacresol, phenol, zinc acetate. Acidity na maganin yana kusan tsaka tsaki saboda ƙari na hydrochloric acid ko sodium hydroxide.

Yana da muhimmanci sosai: Dakatar da ciyar da mafia na kantin magani koyaushe. Endocrinologists suna sa mu daina kashe kuɗi akan magunguna lokacin da za'a iya daidaita sukari na jini don kawai 143 rubles ... >> >> karanta labarin Andrey Smolyar

Alamu don nadin Tresiba

Ana amfani da miyagun ƙwayoyi a hade tare da insulins mai sauri don maganin maye gurbin maganin cututtukan cututtukan fata don cututtukan cututtukan biyu. Tare da nau'in cuta ta 2, kawai ana iya yin insulin dogon magani a farkon matakin.

Da farko, umarnin Rashanci don amfani dashi yana ba da izinin amfani da Treshiba na musamman ga marasa lafiya na manya.

Bayan nazarin da ke tabbatar da amincinsa ga kwayoyin da ke girma, an yi canje-canje ga umarnin, yanzu ya ba da damar amfani da maganin a cikin yara daga 1 shekara.

Tasirin degludec akan ciki da haɓaka jarirai har zuwa shekara guda ba'a yi nazarinsa ba, sabili da haka, ba'a ƙaddamar da insulin insulin don waɗannan nau'ikan marasa lafiya ba. Idan mai ciwon sukari ya lura da mummunan rashin lafiyan halayen ga degludec ko wasu abubuwan haɗin ginin, yana da kyau a nisanci jiyya tare da Tresiba.

Reres insulin Treshiba

Arcadia, mai shekara 44 ya sake duba shi. Nau'in cuta guda 1, ina amfani da insulin Treshiba tsawon wata 1. Yanzu, da safe da maraice, sugar na a kan komai a ciki kusan iri ɗaya ne, akan Levemire da yamma koyaushe yana ɗan ƙara ƙaruwa. A dare, glycemia gabaɗaya abin dacewa ne, sauƙaƙewa ba su wuce 0.5 ba, ana bincika su musamman. Ya zama mafi sauƙi don kiyaye sukari daidai lokacin ƙoƙarin jiki, yanzu ba ya faɗuwa sosai kamar yadda ya gabata. Tsawon wata daya a cikin dakin motsa jiki babu wani ciwo guda daya. Abin ban sha'awa shine, yawan tsawon insulin din ya kasance iri daya gare ni, kuma NovoRapid ya rage da kashi daya bisa hudu. A bayyane yake, wani ɓangare na ayyukan Levemir an yi shi da gajeren insulin, amma ban ma san shi ba.Polina, 51 ya duba shi. Masana ilimin kimiya na endocrinologist sun bani shawarar Treshiba a matsayin mafi kyawun insulin da ake samu yanzu. Ba zan iya jimre da shi ba, bayan allura, matsanancin ƙoshin jiki, ƙaiƙayi, ƙwanƙwasa jini ya zama sau da yawa, a sakamakon haka na koma Lantus. Ee, kuma farashin Treshiba bai yi farin ciki ba, a gare ni ya yi tsada da yawa.Arcadia, mai shekaru 37 ya bita. Yarinya 10 years old, tana da ciwon sukari daga watan Yunin da ya gabata. Daga farkon, sun zaɓi allurai na Tresiba da Apidra a asibiti, don haka ba zan iya kwatanta su da sauran abubuwan rashin lafiya ba. Babu wasu matsaloli na musamman da Tresiba, fata kawai ya zube da farko. Da farko, an magance matsalar tare da daskararru, to, rashin jin daɗi ya zama lalacewa. Muna amfani da Dekskom, saboda haka ina da duk sukari a hannuna. Da dare, jadawalin glycemic kusan kusan a kwance yake, Tresiba yana aiwatar da ayyukanta daidai.Da fatan za a kula: Shin kuna mafarki don kawar da ciwon sukari sau ɗaya kuma? Koyi yadda ake shawo kan cutar, ba tare da amfani da magunguna masu tsada ba, amfani kawai ... >> kara karantawa anan

Tresiba: umarnin don amfani, farashi, sake dubawa da kuma alamun analogues

Daga cikin matsalolin da ke haifar da cutar, da yawa daga masu ciwon sukari suna kiran rashin iya barin gida na dogon lokaci don kar a rasa allura. Akwai magunguna waɗanda zasu iya kawar da wannan matsalar.

"Tresiba" shine insulin wanda za'a iya amfani dashi bisa ga umarnin don amfani sau ɗaya a rana kuma a lokaci guda jin babban. Kuma zaku iya ɗaukar sirinji tare da ku har ma a kan tafiya.

Waɗanne fa'idodi ne wannan maganin yake da shi? Bari mu kara zurfafa bincike.

Aikin magunguna

Yana da dukiya mai ɗaukar nauyi na aiki. Insulin degludec an kafa shi ta hanyar recombination na DNA.

Sau ɗaya a cikin jiki, yana ɗaure wa masu karɓar insulin na mutum kuma yana fara aiki a matsayin ɓangaren hadaddun.

Yin amfani da glucose ta kyallen tsoka da ƙwayoyin mai yana ƙaruwa a cikin hulɗa tare da hadaddun mai karɓa. An rage yawan faruwar cututtukan jini na rashin haihuwa a cikin jini.

Pharmacokinetics

Tsawon lokacin aiki ya wuce awanni 42. Tare da gabatarwar abu sau ɗaya a rana, aikin ɗaukar nauyi yana faruwa a cikin kullun. Metabolites din da bangaren abin da yake aiki ya rushe basa aiki. Rabin rayuwar kusan awowi 25 ne.

Ciwon sukari (mellitus) a cikin dukkan tsaran shekaru (sai dai yara kanana yan shekara 1).

Yawan abin sama da ya kamata

Tare da haɓakawarsa, hypoglycemia na iya faruwa. Babban bayyanar cututtuka: rauni, pallor na fata, ƙarancin sani har zuwa asararta da haɓakar ƙwayar cuta, yunwa, haushi, da sauransu.

Za'a iya cire nau'i mai laushi akan nasu ta hanyar cin abincin mai wadataccen carbohydrates. An cire hypoglycemia matsakaici da mai tsanani tare da allura na glucagon ko dextrose bayani, to ya kamata ku shigar da mutum cikin hankali kuma ku ciyar da shi da abinci mai arziki a cikin carbohydrates.

Tabbatar da tuntuɓi likita don daidaitawa na kashi.

Hulɗa da ƙwayoyi

Ayyukan miyagun ƙwayoyi "Tresiba" yana haɓaka ta:

• na baka hormonal hana,
• hodar iblis,
• karin bayani
• somatropin,
• GKS,
• tausayawa
• danazol.

Sakamakon maganin zai iya raunana:

• na baki hypoglycemic kwayoyi,
• ba zaɓin beta-blockers ba,
• GLP-1 agonists mai karɓa,
• Salamamalla
• MAO da ACE inhibitors,
• magungunan anabolic steroid
• sulfonamides

Masu hana Beta-bloc suna iya rufe alamun bayyanar cututtukan jini. Ethanol, kazalika da "Octreotide" ko "Lanreotide" duka zasu iya raunanawa da haɓaka tasirin maganin.

Umarni na musamman

Hadarin hypoglycemia yana ƙaruwa tare da ƙoƙarin jiki, damuwa, tsallake abinci ko allurar magunguna, wasu cututtuka. Ya kamata mai haƙuri ya san alamun cutar kuma zai iya ba da taimakon farko.

Rashin isasshen ƙwayar insulin yana haifar da ci gaban hyperglycemia ko ketoacidosis mai ciwon sukari. Ya kamata ku san alamun su da hana haɓaka irin waɗannan yanayin.

Sauyawa zuwa wani nau'in insulin ana yi ne a ƙarƙashin kulawar kwararrun. Ana iya buƙatar daidaita yanayin aiki.

Rashin ciwon sukari na iya faruwa a farkon farfaɗo.

"Tresiba" yana da ikon yin tasiri ga gudanarwar abin hawa, wanda ke da alaƙa da haɓakar cutar haɓaka. Sabili da haka, don guje wa yanayi mai haɗari da ke barazana ga lafiyar mai haƙuri da sauransu, tambayar ya kamata a tuƙa mota yayin kwantar da hankalin insulin tare da likitan halartar.

Yi amfani da ƙuruciya da tsufa

Ana iya amfani dashi don kula da yaran da suka girmi shekara 1. Koyaya, ya kamata a tuna cewa ga yara an zaɓi sashi sosai, kuma ana kula da yanayin jikin mafi kusanci.

Sanya jiyya ga tsofaffi. A lokaci guda, yana da mahimmanci a san cewa a cikin tsofaffi tsofaffi mutum zai iya haɓaka da sauri, saboda haka ana buƙatar saka idanu akai-akai game da yanayin kiwon lafiya.

Ka'idojin aiki

Tresiba FlexTouch insulin yana da ka'idojin aiki guda ɗaya kamar na maganin Lantus, sananne ga yawancin masu ciwon sukari. Bayan kwayoyin sun shiga jikin mutum, ana hada su da manyan sifofi, wadanda kuma ake kira multicameras. Suna ƙirƙirar daɗaɗɗan magunguna. Bugu da ari, an yanke kananan abubuwa daga gare shi, wanda ke ba da damar cimma irin wannan sakamako mai dorewa.

Masu masana'antar sun ce tsawon lokacin miyagun ƙwayoyi ya wuce sa'o'i 40. A cewar wasu karatun, har ma ya isa daidai kwana biyu. A wannan batun, yana iya zama alama cewa ana iya amfani da wannan wakili ƙasa da insulin na yau da kullum Ba kowace rana ba, amma sau ɗaya kowace kwana biyu. Amma a zahiri wannan ba haka bane. Masana sun ba da shawara sosai cewa kar su tsallake allura ta yau da kullun, don kada ku raunana tasiri da tasirin wannan maganin.

Nazarin sabon "Tresib Insulin" sun tabbatar da cewa maganin yana daidai da tasiri ga marasa lafiya na yara da tsofaffi. Hakanan babu wasu maganganu marasa kyau daga marasa lafiya waɗanda su ma suna da damuwa game da matsaloli tare da hanta da kodan.

Babban sinadaran aiki na tsawan "Insulin Tresib" ya tabbatar da amfani - degludec. Idan aka kwatanta da glargine da aka yi amfani da shi a Lantus, yana haifar da raguwar adadin cututtukan hypoglycemia.

Umarnin don amfani da "Insulin Tresiba" yayi cikakken bayani game da sashi don kowane rukuni na marasa lafiya. Ana gudanar da maganin ne na musamman subcutaneously, gudanar cikin jijiya an contraindicated. Wannan yakamata ayi sau daya a rana.

Yana da mahimmanci a lura cewa miyagun ƙwayoyi sun dace da duk magunguna masu rage sukari waɗanda suke samuwa a cikin allunan, kazalika da sauran nau'ikan insulin. Sakamakon haka, an wajabta shi daban, kuma a wasu lokuta a matsayin ɓangare na rikicewar jiyya.

Idan mai haƙuri yana gudanar da insulin da farko, kashi ya kamata ya zama raka'a 10. Sannan a hankali an daidaita shi, wanda zai dogara da bukatun kowane mutum.

Idan mai haƙuri ya karɓi wasu nau'in insulin, sannan ya yanke shawarar canzawa zuwa Treshiba, ana lissafin kashi na farko a gwargwado ɗaya zuwa ɗaya. Wannan yana nufin cewa ya kamata a sarrafa insulin insulin daidai gwargwadon yadda aka gudanar da insulin na basal.

Idan mai haƙuri na wani ɗan lokaci ya kasance sau biyu na karɓar insulin, to ya kamata a ƙayyade adadin tare da halartar malamin halartar daban daban. Wataƙila zai ragu. Hakanan za'a lura da yanayin guda ɗaya idan matakin glycated haemoglobin a cikin mara haƙuri ya zama ƙasa da 8%.

Tabbas, a nan gaba, mai haƙuri tabbas zai buƙaci daidaitawar sashi na mutum a ƙarƙashin kula da matakin sukari da ke cikin jini.

Manuniya da contraindications

Umarnin zuwa "Tresiba insulin" ba tare da izini ba da shawarar yin amfani da wannan magani a lura da masu cutar sukari a cikin majinyata na manya.

A wannan yanayin, an sanya maganin a cikin wadannan rukuni na marasa lafiya:

• yara da matasa da ke ƙasa da shekara 18,
• mata masu juna biyu
• reno uwaye
• marasa lafiya tare da hankali na mutum ga babban aiki na miyagun ƙwayoyi ko kowane ɓangarorin kayan aikinsa na taimako.

Ana samun magungunan a cikin hanyar samar da mafita don gudanar da aikin subcutaneous. Babban sinadaran aiki shine insulin degludec.

Phenol, glycerol, zinc, hydrochloric acid, da kuma ruwan da ake buƙata don injeals ana amfani dashi azaman kayan taimako a cikin wannan maganin.

A cikin kunshin ɗaya, sirinji biyar tare da 3 ml na abu a cikin kowane.

Insulin degludec yana iya ɗaukar takamaiman ga mai karɓar insulin na mutum. Kai tsaye hulɗa tare da shi, ya fahimci tasirin magani, wanda kusan yake daidai da aikin insulin ɗan adam.

Yana da mahimmanci a lura cewa dukiyar hypoglycemic na wannan magani ta kasance ne saboda iyawar inganta haɓakar glucose. Wannan ya faru ne saboda ɗaurin insulin kanta ga masu karɓa mai kitse da ƙwayoyin tsoka. Yana da mahimmanci cewa a cikin layi daya tare da wannan, yawan rage yawan haɓakar glucose ta hanta yana raguwa sosai.

Neman Masu haƙuri

Reviews na masu ciwon sukari game da Tresib's Insulin galibi ana iya haɗuwa da ita kawai. Mafi yawanci ana yin allurar ne da dare. Wannan yana bawa mutum mai daidaitaccen sukari daidai ya farka da safe cikin yanayi na al'ada.

Babban abu shine cewa an zaɓi kashi daidai. A cikin sake dubawar masu ciwon sukari tare da kwarewa akan "Insulin Tresiba" an lura cewa kafin bayyanar wannan nau'in wannan magani, duk bambance-bambancen da suka gabata sunyi aiki da ƙarancin lokaci, wanda ya haifar da matsala da yawa. Yin azumin glucose yana da matsala sosai.

A lokaci guda, da yawa a cikin sake dubawa da Insulin Tresibe suna jaddada cewa mahimmancin amfani da miyagun ƙwayoyi ya ta'allaka ne da cewa tare da taimakonsa yana yiwuwa a sami ƙarin ƙanƙantar da jini kaɗan idan aka kwatanta da sauran hanyoyin masu kama. Misali, tare da "Lantus" ko "Levemire." Bugu da ƙari, haɗarin haɓakar haɓakar haɓaka ya ragu sosai, kodayake har yanzu ya kasance idan ya kasance yawan zubar jini. An lura da wannan a cikin bita da kuma umarnin don amfani da insulin Tresib.

Tare da duk tabbatattun abubuwan, yana da kyau a lura cewa har yanzu ana samun ra'ayoyin marasa kyau game da wannan magani. Gaskiya ne, ra'ayoyi marasa kyau game da insulin na Tresib suna da alaƙa ba tare da tasirin sa ba, amma tare da tsada mai yawa.

Ya kamata a lura cewa marasa lafiya masu arziki ne kawai zasu iya wadatar da shi, tunda wannan magani yana da tsada fiye da sauran analogues. Idan kuna da irin wannan kuɗin kuɗin ku, ya kamata ku tattauna sauyawa zuwa sabon insulin tare da likitan ku. Muna jaddada cewa tare da ciwon sukari, ana tsara magunguna da yawa daban-daban, dangane da yanayin mai haƙuri. Bugu da kari, yana da muhimmanci a tantance matakin gwargwadon yanayin lafiyar wani mai haƙuri.

Ya kamata a sani cewa Insulin Tresiba a halin yanzu yana da kusan sau uku mafi tsada fiye da Levemir da Lantus, waɗanda kuma ana amfani da su sosai a cikin cututtukan sukari na mellitus da yawa daga marasa lafiya.

Masana da ke da kusanci da kasuwancin kantin magani suna lura cewa a cikin shekaru masu zuwa mutum zai iya dogaro da bayyanar analogues, waɗanda kayan aikinsu ba za su yi ƙyalli ba irin na Insulin Tresib. Har yanzu kuna karanta a hankali da kuma sharhi game da waɗannan kwayoyi, amma ba lallai ne ku dogara da waɗannan kwayoyi don zama mai rahusa ba. Wannan ya faru ne sabili da gaskiyar cewa a halin yanzu akwai fewan kamfanoni masu daraja a duniya waɗanda ke samarwa da insulin na zamani da ingancin yanayi. A lokaci guda, akwai ra'ayi cewa akwai yarjejeniya tsakanin kamfanoni wanda ke ba su damar adana farashin a cikin tsayayyen matakin.

Kwatanta tare da analogues

Wannan nau'in insulin yana da adadin analogues. An ba da shawarar ku san kanku tare da su don kwatanta kaddarorin.

Yawancin sake duba masu ciwon sukari tare da gogewa akan wannan magani tabbatacce ne. Lokaci da tasiri na aikin, raunin sakamako masu illa ko ƙarancin ci gaban su an lura. Magungunan sun dace da marasa lafiya da yawa. Daga cikin minuses akwai babban farashi.

Oksana: “Ina zaune a kan insulin tun ina ɗan shekara 15. Na gwada magunguna da yawa, yanzu na tsaya a Tresib. Ya dace sosai don amfani, duk da tsada. Ina son irin wannan sakamako mai tsawo, babu wani yanki na dare na hypo, kuma kafin hakan yakan faru sau da yawa. Na gamsu. "

Sergey: "Kwanan nan na canza zuwa magani insulin - magungunan sun daina taimakawa. Likitan ya ba da shawarar gwada alkalami na Tresiba.

Zan iya faɗi cewa ya dace da kai kanka allura, ko da yake sababbi ne ga wannan. Ana nuna sashi akan abin rike tare da lakabin, saboda haka baza'a kuskure ku ba nawa kuke buƙatar shigar. Sugar yana da santsi da tsawon rai.

Babu wani sakamako na gefen da zai gamshi bayan wasu kwayoyin. Magungunan sun dace da ni kuma ina son shi. ”

Diana: “Labari kakara yana da nau'in ciwon suga. Ni kan yi allura, domin ita kanta tana jin tsoro. Likita ya shawarce ni in gwada Tresibu. Yanzu tsohuwar kanta zata iya yin allura. Ya dace da cewa sau ɗaya kawai a rana ana buƙatar yin shi, kuma tasirin yana daɗewa. Kuma lafiyar ta ta zama mafi kyau. ”

Denis: “Ina da nau'in ciwon sukari na 2, Na riga na yi insulin. Ya zauna na dogon lokaci akan "Levemire", ya daina riƙe sukari. Likita ya canza zuwa Tresibu, kuma na karba shi kan fa'idodi. Maganar da ta dace sosai, matakin sukari ya zama karbuwa, babu abin da ke wahala. Dole ne in gyara ɗan abinci, amma ya ma fi kyau - nauyi ba ya ƙaruwa. Na yi farin ciki da wannan maganin. ”

Alina: “Bayan haihuwar jariri, sun gano ciwon sukari na 2. Na shiga insulin, na yanke shawarar gwada shi da izinin likita Treshibu. Samu akan fa'idodi, don haka ƙari ne. Ina son cewa tasirin yana da tsayi da daɗewa. A farkon jiyya, an samo maganin retinopathy, amma an canza sashi, abincin ya ɗan canza kadan, kuma komai yana cikin tsari. Kyawawan magani. ”

Tsarin ilimin rayuwa (ICD-10)

Yanayin bayardawa daga magunguna:

Hanyoyi don amfani

An tsara katuwar Penfill ® don amfani da tsarin allurar insulin Novo Nordisk da allurar NovoFine ® ko NovoTvist up har tsawon mm 8.

Tresiba ® Penfill ® da allura sune don amfanin kai kaɗai. Ba a yarda da gyaran kicin ba.

Ba za ku iya amfani da miyagun ƙwayoyi ba idan mafita ta daina zama mara kyau da launi.

Ba za ku iya amfani da miyagun ƙwayoyi ba idan an daskarar da shi.

Jefar da allura bayan kowace allura. Bi ƙa'idodin zubar da shara na gida don kayan abinci.

Cikakkun umarnin don amfani - duba umarnin.

Saiti da tsari na sakin Tresib

Abubuwan da ke aiki da magungunan Tresib suna sake zama insulin degludec na ɗan adam. Ana samun insulin a matsayin mafita mara launi don gudanarwa a ƙarƙashin fata. An yi rajista nau'i biyu na sakin:

1. Sashi 100 PIECES / ml: insulin degludec 3.66 MG, alkalami mai narkewa tare da 3 ml na bayani. Yana ba ku damar shiga cikin raka'a 80 a cikin ƙarfe na 1 naúrar. A cikin kayan kunshin 5 FensTouch.
2. Sashi 200 PIECES ta 1 ml: insulin degludec 7.32 mg, 3 ml allura, zaku iya shigar da 160 PIECES a cikin karuwar 2 PIECES. A cikin kunshin akwai akwai FensTouch alkalami 3.

Alƙalami don gabatarwar insulin ana iya amfani dashi, don maimaita allurar maganin.

Kaddarorin Treshiba Insulin

Sabbin insulin na matsanancin aiki da tsawon-lokaci suna da mallakin depot a cikin subcutaneous tissue a sigar mai narkewa mai dumbin yawa. Wannan tsarin a hankali yana fitar da insulin a cikin jini. Sakamakon kasancewar insulin a cikin jini, yawanci glucose din da yake gudana a cikin jini yana da tabbas.

Babban fa'idar Tresib shine bayanin martaba na hypoglycemic. Wannan magani a cikin 'yan kwanaki ya isa ga wani sinadari na glucose kuma yana kula da shi duk lokacin amfani, idan mara lafiyar bai keta tsarin tsarin gudanarwa ba kuma yana bin ƙididdigar insulin kuma yana bin ka'idodin tsarin abinci mai gina jiki.

Ayyukan Tresib akan matakin glucose a cikin jini an bayyana shi ne ta hanyar amfani da glucose ta hanyar tsokoki da tsopose nama a matsayin tushen samar da makamashi a cikin tantanin halitta. Tresiba, hulɗa tare da masu karɓar insulin, yana taimakawa glucose shawo kan ƙwayar sel. Bugu da ƙari, yana ƙarfafa ayyukan glycogen na hanta da ƙwayar tsoka.

Ana nuna tasirin Tresib akan metabolism a cikin gaskiyar cewa:

1. Babu sabon kwayoyin glucose da aka kirkira a hanta.
2. An rage raguwar glycogen daga shagunan da ke cikin sel na hanta.
3. Abubuwan da ke tattare da mai sunadarai ne, kuma barkewar mai zai tsaya.
4. Matsayin lipoproteins a cikin jini yana ƙaruwa.
5. Tsarin tsoka yana karawa.
6. Ana haɓaka sifar protein kuma an rage haɓaka aikinta lokaci guda.

Tresiba FlexTouch insulin tana kare garkuwar sukari a cikin rana bayan gudanarwar. Jimlar lokacin aikinta ya wuce awanni 42. Ana samun daidaituwa akai-akai a cikin kwanaki 2 ko 3 bayan allurar ta farko.

Amfani na biyu mara tabbas na wannan ƙwayar cuta shine ɗanɗano haɓakar haɓakawar jini, gami da maraice, idan aka kwatanta da sauran shirye shiryen insulin. A cikin binciken, an lura da irin wannan tsarin a cikin matasa da tsofaffi marasa lafiya.

Shaidun marasa lafiya da suka yi amfani da wannan magani sun tabbatar da amincin amfani da shi dangane da raguwar hauhawar sukari da hare-haren hypoglycemia. Nazarin kwatankwacin Lantus da Tresib sun nuna daidaitattun tasirinsu don kiyaye yawan kwantar da hankalin insulin.

Amma amfani da sabon magani yana da fa'idodi, tunda yana yiwuwa a rage kashi na insulin a kan lokaci zuwa 20-30% kuma rage mahimmancin yawan hare-hare na dare na faɗuwar sukari na jini.

Tresiba yana da tasirin gaske game da matakin haemoglobin, wanda ke nufin zai iya rage haɗarin kamuwa da cutar siga.

Wanene Treshiba aka nuna?

Babban nuni ga adana insulin na Treshib, wanda zai iya kula da matakin manufa na glycemia, shine ciwon sukari.

Contraindications don amfani da miyagun ƙwayoyi sune hankalin mutum zuwa abubuwan da aka gyara na mafita ko abu mai aiki. Hakanan, saboda rashin ilimin ƙwayoyi, ba a ba da umarnin ga yara 'yan ƙasa da shekara 18, uwaye masu shayarwa da mata masu juna biyu.

Kodayake lokacin fitar insulin ya fi kwana 1.5, ana bada shawarar shigar da shi sau ɗaya a rana, zai fi dacewa a lokaci guda. Mai ciwon sukari mai nau'in cuta na biyu zai iya karɓar Tresib ko hada shi da magunguna masu rage sukari a allunan. Dangane da alamu da nau'in ciwon sukari na biyu, an wajabta insulins na gajere tare da shi.

A cikin nau'in 1 na ciwon sukari na mellitus, Treetb FlexTouch ana tsara shi koyaushe tare da insulin gajere ko matsanancin-gajeren lokaci don rufe buƙatar karɓar carbohydrates daga abinci.

Sashi na insulin an ƙaddara shi ta hanyar hoto na asibiti na mellitus na sukari kuma an daidaita shi dangane da matakin glucose na jini.

Wa'adin sabon kashi na Tresib an aiwatar da shi:

• Lokacin canza aikin jiki.
• Lokacin juyawa zuwa wani abinci.
• Tare da cututtuka masu yaduwa.
• A take hakkin aikin endocrine tsarin - ilimin halittar jini na thyroid gland shine yake, guguwar glandon gland ko adrenal gland shine yake.

Ana iya yin maganin Tresiba don marasa lafiya tsofaffi waɗanda ke fama da koda ko gazawar hanta, idan har ana kulawa da matakan glucose na jini da kyau.

Ga marasa lafiya da ke fama da ciwon sukari na 2, suna farawa da kashi 10 NA FARKO, suna zaɓin kowane kashi. Marasa lafiya da irin nau'in cutar ta farko, lokacin da suke juyawa zuwa Treshiba daga sauran daskararru masu daukar dogon lokaci, suna amfani da ka’idar “maye gurbin kashi-kashi”.

Idan mai haƙuri ya sami injections na basal insulin 2 sau, to, zaɓi na kashi ana aiwatar da su akan asalin bayanan glycemic daban daban. Tresiba yana ba da damar karkacewa a cikin yanayin gudanarwa, amma ana bada shawarar tazara zuwa akalla 8 hours.

Za'a iya shigar da sashin da aka rasa a kowane lokaci, washegari kuna iya komawa cikin shirin da ya gabata.

Dokoki don amfani da Treshiba FlexTouch

Ana sarrafa Tresib ne kawai a ƙarƙashin fata. An contraindicated gudanarwar cikin ciki saboda ci gaban mai girma hypoglycemia. Ba'a ba da shawarar da za a gudanar da shi ta intramuscularly kuma a cikin farashin famfo

Wurare don gudanar da aikin insulin shine kashi na gaban ko na baya na cinya, kafada, ko bangon ciki. Kuna iya amfani da yanki mai dacewa na dabi'a, amma kowane lokaci don farashi a cikin sabon wuri don rigakafin lipodystrophy.

Don sarrafa insulin ta amfani da alkalami na FlexTouch, dole ne ku bi jerin ayyukan:

1. Duba alamar rubutu na alkalami
2. Tabbatar da bayyana ma'anar maganin insulin
3. Sanya allura da tabbaci a kan makarar
4. Jira har sai digon insulin ya bayyana a allura
5. Saita kashi ta juya mai zazzage kashi
6. Saka allura a karkashin fata domin a bayyane adadin maganin.
7. Latsa maɓallin farawa.
8. A saka insulin.

Bayan allura, allura ya kamata ya kasance ƙarƙashin fata don wani sakan 6 don cikakken ɗaukar insulin. Sannan dole ne a ja hannun. Idan jini ya bayyana akan fatar, to, an dakatar dashi da auduga.Karka tausa wurin allurar.

Dole ne kawai a gudanar da allurar ta hanyar amfani da allon alkalami a cikin yanayin cikakkiyar tsauraran aiki. Don yin wannan, fata da hannayenku kafin allura dole ne a bi dasu tare da hanyoyin maganin antiseptics.

Kada a ajiye alkalami na FlexTouch a yanayin zafi ko zafi. Kafin buɗewa, an adana maganin a cikin firiji a kan shiryayyen tsakiya a zazzabi na 2 zuwa 8. Kar a daskare mafita. Bayan amfani na farko, an adana alƙalin a zazzabi a ɗakuna na sama da makonni 8.

Karka wanke ko shafa mai a hannu. Dole ne a kiyaye shi daga ƙazantarwa kuma a tsabtace shi da rigar rigar. Ba za a yarda da fadada da dunƙulen ba. Bayan cikakken amfani, alkalami ba zai sake cikawa ba. Ba za ku iya gyara ko watsa shi da kanku ba.

Don hana gudanarwar da ba ta dace ba, kuna buƙatar adana insulins daban daban, kuma bincika alamar kafin amfani don kar ku sha wani insulin da gangan. Hakanan kuna buƙatar bayyananniyar lambobi a kan kan adadin kashin. Idan kuna da hangen nesa kaɗan, kuna buƙatar amfani da taimakon mutane masu kyakkyawan gani da kuma horar da su don sarrafa Tresib FlexTouch.

Kammalawa

Tresiba magani ne mai kyau don maganin cututtukan cututtukan koda. Ya fi dacewa da yawancin masu ciwon sukari, ana iya samun shi ta hanyar fa'idodi. Likitocin sun yaba wa likitan don ingancinsa a jiyya da tsawon lokacin da aka yi, ba da damar marasa lafiya su jagoranci rayuwa mai amfani ba tare da yin illa ga lafiya ba. Don haka wannan magani ya cancanci kyakkyawan suna.

Pharmacodynamics

Magungunan Tresiba ® FlexTouch ana wani kwatanci ne na insulin na mutum na wani karin aiki, wanda aka samar da shi ta hanyar kimiyyar halittar DNA ta hanyar amfani da wani irin yanayi. Saccharomyces cerevisiae.

Hanyar aikin. Insulin degludec takamaiman yana ɗaure wa mai karɓar inshinin halittar ɗan adam kuma, yin ma'amala dashi, yasan tasirin magungunansa masu kama da tasirin insulin ɗan adam.

Tasirin hypoglycemic na insulin degludec shine saboda karuwar amfani da glucose ta hanyar kyallen takarda bayan an danganta insulin zuwa tsoka da mai karban kwayar halitta da kuma raguwa a lokaci guda a cikin yawan samarwar glucose ta hanta.

Magungunan Tresiba ® FlexTouch ® shine kwatankwacin ƙarancin ɗan adam na insulin na mutum mai ɗaukar nauyi, bayan s / c allura yana samar da mai narkewa mai yawa a cikin ƙwaƙwalwar subcutaneous, daga inda ake samun ci gaba mai ɗorewa na insulin degludec zuwa cikin jijiyoyin jijiyoyin jiki, samar da matsanancin-lokaci, ɗakin bayanin martaba na aiki da tsayayyar ƙwayar magani duba Hoto na 1).

A cikin sa'o'i 24 na sa'o'i na tasirin hypoglycemic na miyagun ƙwayoyi a cikin marasa lafiya wanda aka kula da sashin insulin degludec sau ɗaya a rana, Tresiba ® FlexTouch ®, ya bambanta da insulin glargine, ya nuna sigar V_d tsakanin aiki a cikin sa'o'i 12 na farko da na biyu (AUC)_{GIR0-12h, SS}/ Auc_{GIRtotal, SS} =0,5).

Hoto 1. Matsakaicin matsakaiciyar matsakaici a cikin awa 24 na glucose - C_ss insulin degludec 100 U / ml 0.6 U / kg (1987 binciken)

Tsawon lokacin da miyagun ƙwayoyi Tresiba ® FlexTouch ® sun fi awanni 42 a cikin kewayon maganin warkewa. C_ss magani cikin jini jini ana samunsa kwanaki 2-3 bayan gudanar da maganin.

Insulin degludec a cikin jihar C_ss yana nuna mahimmancin ƙarancin (sau 4) idan aka kwatanta da insulin glargin yau da kullun masu bambanci na ayyukan hypoglycemic, wanda aka ƙididdige ta hanyar yawan daidaituwa na canji (CV) don nazarin tasirin maganin ƙwaƙwalwar ƙwayar cuta a cikin lokacin tazara guda (AUC_{GIR.τ, SS}) kuma a tsakanin lokacin daga 2 zuwa 24 hours (AUC_{GIR2-24h, SS}), (duba Tebur 1.)

Canjin yanayin bayanan yau da kullun na aikin hypoglycemic na miyagun ƙwayoyi Tresiba da insulin glargine a cikin jihar C_ss a cikin marasa lafiya da nau'in 1 ciwon sukari

a CV: coefficient of intraindividual bambancin,%.

b SS: Cutar da ƙwayar cuta a cikin ma'auni.

c AUC_{GIR2-24h, SS}: sakamako na rayuwa a cikin awanni 22 na karshe na tazara tazara (i.e. babu wani tasiri akan sa na allurar iv insulin yayin gabatarwar lokacin karatuttukan).

An tabbatar da alaƙar layin tsakanin karuwa a cikin yawan ƙwayoyin Tresiba ® FlexTouch its da kuma tasirin hypoglycemic na gaba ɗaya.

Karatun bai bayyana wani bambanci na asibiti a cikin magungunan Tresiba ® na tsofaffi da kuma marasa lafiyar matasa marasa lafiya ba.

Ingantaccen Asibiti da Aminci

Gwajin asibiti ya nuna raguwa iri ɗaya a cikin HbA_1c daga ƙimar farko a ƙarshen binciken akan tushen maganin tare da insulin Treciba ® da insulin glargine 100 IU / ml. Marasa lafiya da ke fama da nau'in 1 na ciwon sukari mellitus (T1DM) tare da maganin Tulinib ® insulin therapy sun nuna wani mummunan yanayin rashin ƙarfi na hypoglycemia mai ƙarfi ko tabbatar da cutar hypoglycemia (gaba ɗaya hypoglycemia da nocturnal hypoglycemia) idan aka kwatanta da insulin glargine 100 IU / ml, kamar lokacin yayin rike da kashi, da kuma tsawon lokacin magani. Marasa lafiya tare da nau'in ciwon sukari na 2 na sukari (T2DM) da aka yi wa maganin Tresib ® insulin ya nuna raguwa sosai a cikin yanayin rashin ƙarfi ko tabbatar da cutar hypoglycemia (gaba ɗaya hypoglycemia da nocturnal hypoglycemia) idan aka kwatanta da insulin glargine (100 IU / ml), kamar a lokacin tabbatarwa allurai, da kuma tsawon lokacin magani, kazalika da rage faruwar cututtukan cututtukan cututtukan jini a duk lokacin jiyya.

A cikin nazarin asibiti, rashin girman kwatancen kwatancen kwayoyi (insulin detemir da insulin glargine) akan Tresiba ® dangane da raguwar HbA_1c daga tushe a karshen binciken. Banda ya kasance sitagliptin, lokacin da Tresiba ® ya nuna mahimmancin ƙididdiga na rage HbA_1c.

Sakamakon nazarin-meta na bayanai daga nazarin bakwai sun nuna fa'idodin maganin insulin na Tresib ® dangane da ƙananan abin da ya faru da aka tabbatar da abubuwan da aka tabbatar da cutar hypoglycemia a cikin marasa lafiya idan aka kwatanta da glargine insulin therapy (100 U / ml) (Tebur 2) da kuma tabbatar da ɓoye yanayin jini. An sami raguwar yawan lokuttan yawan cututtukan jini a cikin lokacin Tresib ® insulin therapy tare da ƙaramin matsakaicin azumin plasma mai azumi yayin da aka kwatanta da insulin glargine (100 IU / ml).

Sakamakon meta-nazarcen bayanai akan abubuwan da ke faruwa na rashin karfin jiki

wani tabbacin hypoglycemia wani lamari ne na hypoglycemia wanda aka tabbatar ta hanyar auna yawan glucose plasma glucose b Abubuwa na hypoglycemia bayan mako na 16 na maganin.

c Lambar mahimmanci.

Babu wani ingantaccen tsarin samarda kwayoyin zuwa insulin bayan magani tare da Tresiba® na wani tsawan lokaci. A cikin nazarin asibiti a cikin marasa lafiya tare da T2DM da aka bi da Tresiba® a hade tare da metformin, ƙari na liraglutide ya haifar da raguwar ƙididdigar ƙananan ƙwayoyin cuta a cikin HbA_1s da nauyin jiki. Halin hauhawar jini ya kasance ƙididdigar ƙididdigar ƙwaƙwalwar ƙwaƙwalwa ta rage tare da ƙari na liraglutide idan aka kwatanta da ƙari na kashi ɗaya na insulin insulin.

Kimanta tasirin CCC. Don kwatanta lafiyar zuciya yayin amfani da miyagun ƙwayoyi Tresiba da insulin glargine (100 PIECES / ml), an gudanar da binciken KYAUTATA da ke tattare da marasa lafiya 7637 da ke da T2DM da kuma babban haɗarin haɓaka al'amuran zuciya.

An tabbatar da lafiyar lafiyar zuciya da amfani da magungunan Tresiba® a kwatancen insulin glargine (Figure 2).

N Yawan marasa lafiya da abin da ya faru na farko da aka tabbatar da Kwamitin Ba da Shawara a kan Bincike na Abubuwan da ba a so (EAC) yayin binciken.

% Rashin yawan marasa lafiya tare da sabon abu na farko da aka tabbatar ta hanyar EAC, dangane da adadin marasa lafiyar da ba a raba su.

Hoto na 2. Shafin gandun daji da ke nuna zurfin bincike na 3-aminci aminci maki uku domin abin da ya faru na zuciya da jijiyoyin jini (CVSS) da kuma ƙarshen bugun zuciya a cikin binciken. KYAUTATA.

Tare da yin amfani da insulin glargine da magani Tresiba ®, an sami irin wannan ci gaba a matakan HbA_1s da kuma raguwa mafi yawa a cikin jini na plasma glucose yayin amfani da miyagun ƙwayoyi Tresiba ® (tebur 3).

Tresiba ® ya nuna fa'ida a kan insulin glargine dangane da ƙananan abin da ya faru na rashin ƙarfin jini da ƙananan kashi na marasa lafiya waɗanda suka kamu da matsanancin rashin ƙarfi na jini. Mitar abubuwa masu rauni na rashin karfin jini a jiki sun ragu sosai tare da amfani da miyagun ƙwayoyi Tresiba idan aka kwatanta da insulin glargine (Table 3).

Sakamakon bincike KYAUTATA

Matsakaicin darajar HbA_1s, %

Mitar yawan zubar jini (a cikin shekaru 100 na haƙuri - shekaru na kallo)

Mai tsananin rashin ƙarfi

Mai tsananin rashin lafiyar hypoglycemia 2

Hadarin dangi: 0.47 (0.31, 0.73)

Matsakaicin marasa lafiya tare da haɓakar al'amuran cututtukan jini (% na marasa lafiya)

Mai tsananin rashin ƙarfi

Alamar damuwa: 0.73 (0.6, 0.89)

1 additionari ga daidaitaccen magani don maganin cututtukan siga da cututtukan zuciya.

2 Tsarin bacci mai tsanani a daren shine hypoglycemia wanda ya faru a lokacin lokacin rana tsakanin 0 da 6 na safe.

Yara da matasa. A cikin binciken asibiti a cikin yara da matasa masu fama da ciwon sukari na 1, yin amfani da Tresiba ® sau ɗaya a rana ya nuna irin wannan raguwa a cikin HbA_1s har ya zuwa mako na 52 da karin bayyani mai yawa a cikin azumi na plasma glucose dangi da dabi'un kwatancen kwatankwacin amfani da kwatancen kwatancen (insulin detemir 1 ko sau 2 a rana). An sami wannan sakamakon ta hanyar amfani da miyagun ƙwayoyi Tresiba a cikin kashi ɗaya cikin ɗari 30% ƙasa da insulin na detemir insulin. Mitar (abubuwan mamaki a cikin shekara-shekara na haƙuri) na abubuwan da suka faru na mummunan rashin ƙarfi a cikin jini (ma'anar Societyungiyar forasa ta Duniya don Nazarin Ciwon Cutar na Ciwon Cutar Cutar na Mellitus (DM) a cikin yara da matasa. (ISPAD), 0.51 idan aka kwatanta da 0.33), tabbatar da hypoglycemia (57.71 idan aka kwatanta da 54.05) kuma an tabbatar da hypoglycemia na dare (6.03 idan aka kwatanta da 7.6) ya kasance daidai da Tresiba ® da insulin detemir . A cikin rukunin jiyya duka cikin yara masu shekaru 6 zuwa 11, raunin tabbatar da cutar hypoglycemia ya fi yadda sauran rukunin shekarun ke faruwa. An sami ƙarin cutar haɓaka mai yawa a cikin yara 'yan shekaru 6 zuwa 11 a cikin ƙungiyar Tresiba.. Mitar abubuwa na hyperglycemia tare da ketosis ya ragu sosai tare da amfani da miyagun ƙwayoyi Tresiba idan aka kwatanta da magani tare da insulin detemir, 0.68 da 1.09, bi da bi. Mitar, nau'in da tsananin raunin da ya faru a cikin yawan marasa lafiyar yara ba ya bambanta da na yawan yawan masu fama da cutar sankara.Abubuwan da ke haifar da karewar cutar sun kasance da wuya kuma basu da mahimmanci asibiti. Bayanai game da inganci da aminci a cikin matasa tare da T2DM an tsara su bisa ga bayanan da aka samu daga samari da kuma tsofaffi marassa lafiya tare da T1DM da kuma manya marasa lafiya tare da T2DM. Sakamakon binciken ya ba mu damar bayar da shawarar maganin Tresiba ® don kula da yara masu fama da cutar sukari na 2.

Contraindications

increasedara yawan hankalin mutum ga aiki mai aiki ko kowane ɓangarorin taimako na miyagun ƙwayoyi,

lokacin daukar ciki, lokacin shayarwa (babu wani kwarewar asibiti da amfani da magani a cikin mata yayin daukar ciki da shayarwa),

shekarun yara har zuwa shekara 1 tun ba a gudanar da gwaji na asibiti a cikin yara 'yan ƙasa da shekara 1 ba.

Haihuwa da lactation

Yin amfani da miyagun ƙwayoyi Tresiba ® FlexTouch ® yayin daukar ciki yana contraindicated, saboda Babu ƙwarewar asibiti tare da amfanin sa yayin daukar ciki. Nazarin aikin dabbobi na dabbobi bai bayyana bambance-bambance tsakanin insulin degludec da insulin na mutum dangane da haihuwa da teratogenicity.

Amfani da miyagun ƙwayoyi Tresiba ® FlexTouch ® yayin shayarwa yana da sabani, saboda babu gogewar asibiti tare da matan masu shayarwa.

Nazarin dabbobi sun nuna cewa a cikin beraye, insulin degludec yana kwance a cikin madarar nono, kuma yawan ƙwayar magani a cikin madara nono ya ƙasa da na jini.

Ba'a sani ba ko insulin degludec an keɓance shi cikin madara mata.

Ba a tsammanin bayyanar cututtuka na rayuwa a cikin jarirai da jarirai masu shayarwa.

Haɗa kai

Akwai kwayoyi da yawa waɗanda ke shafar metabolism metabolism.

Za'a iya rage buƙatar insulin: PHGP, agLists na karɓar GLP-1, masu hana MAO, masu hana beta-blockers, ACE inhibitors, salicylates, steroids anabolic da sulfonamides.

Bukatar insulin na iya ƙaruwa: hana maganin hana haihuwa, thiazide diuretics, corticosteroids, hodar iblis, da juyayi, somatropin da danazole.

Masu tallata Beta na iya rufe alamun bayyanar cututtukan jini.

Octreotide / Lanreotide dukansu suna iya haɓaka da rage buƙatar jiki ga insulin.

Ethanol (barasa) duka zasu iya haɓaka da rage tasirin insulin.

Rashin daidaituwa. Wasu abubuwan magunguna, idan aka ƙara Tresib ® FlexTouch ®, na iya haifar da lalata. Ba za a iya ƙara miyagun ƙwayoyi Tresiba ® FlexTouch to zuwa hanyoyin magance jiko ba. Ba za ku iya haxa magungunan Tresiba ® FlexTouch ® da wasu kwayoyi ba.

Umarnin don haƙuri

Dole ne a karanta waɗannan umarni a hankali kafin amfani da pre-cike Tresib ® FlexTouch pen alkalami. Idan mara lafiyar bai bi umarnin a hankali ba, yana iya yin insulin da isasshen ko kuma yalwa da yawa na insulin, wanda zai iya haifar da yawan tasirin ko kuma mai saurin zubar da jini.

Yi amfani da alkairin sirinji kawai bayan mai haƙuri ya koyi yin amfani da shi a ƙarƙashin jagorancin likita ko likitan jinya.

Dole ne a fara bincika alamar a kan alamar sirinji don tabbatar da cewa ya ƙunshi Tresiba ® FlexTouch ® 100 PIECES / ml / Tresiba ® FlexTouch P 200 PIECES / ml, sannan a hankali bincika kwatancen da ke ƙasa, wanda ke nuna cikakkun bayanai game da alƙawirin alkalami da allura.

Idan mara lafiyar yana gani sosai ko yana da wahalar hangen nesa kuma ba zai iya bambance tsakanin lambobin akan takaddar ɗin magani ba, kar a yi amfani da alkalami mai rauni ba tare da taimako ba. Irin wannan mara lafiyar zai iya taimakon mutum ba tare da raunin gani ba, a horar da shi daidai yadda ya dace game da abin da aka riga aka cika FringTouch ® syringe.

Tresiba ® FlexTouch ® 100 U / ml - alkalami mai cika-cika cike da 300 PIECES na insulin degludec. Matsakaicin adadin da mai haƙuri zai iya sanyawa shine raka'a 80 a cikin ƙarfe na 1 naúrar.

Tresiba ® FlexTouch ® 200 UNITS / ml - wani alkalami mai cike da riga-kafin cike wanda ya ƙunshi PIECES 600 na insulin degludec. Matsakaicin adadin da mai haƙuri zai iya sanyawa ya kasance raka'a 160 a cikin adadin raka'a 2.

An tsara alkairin syringe don amfani dashi tare da allurar diski NovoFayn ® ko NovoTvist ® har zuwa tsawon mm 8 mm. Ba a haɗa allura cikin kunshin ba.

Bayani mai mahimmanci. Kula da bayanan da aka yiwa alama kamar yadda mahimmanci, yana da matukar muhimmanci ga yadda yakamata ayi amfani da alkairin sirinji.

Hoto 3. Tresiba ® FlexTouch ® 100 U / ml.

Hoto 4. Tresiba ® FlexTouch ® 200 U / ml.

I. Shirya alkalami don amfani

Bincika sunan da sashi akan kwalin sirinji don tabbatar cewa ya ƙunshi Tresiba ® FlexTouch I 100 IU / ml / Tresiba ® FlexTouch ® 200 IU / ml. Wannan yana da mahimmanci musamman idan mai haƙuri yayi amfani da nau'ikan insulins. Idan yayi kuskure ya saka wani nau'in insulin, to yawan jinin glucose na jini zai iya yawaita ko yayi kasa sosai.

A. Cire murfin daga alkalami na syringe.

B. Tabbatar da cewa shirin insulin a cikin sirinji ya fito bayyananne kuma ba mai launi. Duba cikin taga girman ma'aunin insulin. Idan miyagun ƙwayoyi suna da gajimare, ba za a iya amfani da maɓallin sirinji ba.

C. Yi sabon allura da za'a iya cirewa kuma cire sandararren kariya.

D. Saka allura a alkairin sirinji sai a juya shi domin allurar ta huta cikin hular siririn.

E. Cire maɗaurin murfin na ciki, amma kada a zubar dashi. Zai buƙaci bayan an gama allura don cire cire allurar daga alkairin syringe.

F. Cire da zubar da allura ta ciki. Idan mai haƙuri yayi ƙoƙarin mayar da murfin cikin ciki akan allura, yana iya bazarar farat ɗaya.

Rabin insulin na iya bayyana a ƙarshen allura. Wannan al'ada ce, amma mai haƙuri yakamata ya bincika insulin.

Bayani mai mahimmanci. Dole ne ayi amfani da sabon allura don kowane allura. Wannan yana rage haɗarin kamuwa da cuta, kamuwa da cuta, yaduwar insulin, toshe allura da kuma gabatarwar kashi mara kyau na miyagun ƙwayoyi.

Bayani mai mahimmanci. Karka taɓa amfani da allura idan ya hura ko ya lalace.

Na II. Duba insulin

G. Kafin kowane allura, yakamata a bincika shan inulin. Wannan zai taimaka wa mara lafiyar don tabbatar da cewa ana gudanar da aikin insulin sosai.

Buga raka'a 2 na miyagun ƙwayoyi ta hanyar juya zaɓin mai zaɓin. Tabbatar cewa kwayar ta nuna yana nuna “2”.

H. Yayin riƙe alkalami na syringe tare da allura sama, taɓa sauƙaƙe a saman siririn sirinji sau da yawa tare da yatsanka don iska kuzarin ta tashi.

I. Latsa maɓallin farawa ka riƙe shi a wannan matsayin har sai sirin ɗin ya dawo zuwa “0”. “0” yakamata ya kasance a gaban mai nuna alamar. Wani digo na insulin yakamata ya bayyana a ƙarshen allura. Blean karamin kumfa na iska na iya kasancewa a ƙarshen allura, amma ba za a allura dashi ba. Idan digo na insulin bai bayyana a ƙarshen allura ba, sake maimaita ayyukan G - I (mataki na II), amma ba fiye da sau 6.

Idan digo na insulin bai bayyana ba, canza allura kuma sake maimaita ayyukan G - I sake (Sashi na II).

Idan digo na insulin bai bayyana a ƙarshen allura ba, kar ayi amfani da wannan alkairin sirinji. Yi amfani da sabon alkalami.

Bayani mai mahimmanci. Kafin kowane allura, tabbatar cewa digo na insulin ya bayyana a ƙarshen allura. Wannan yana tabbatar da isar da insulin. Idan digo na insulin bai bayyana ba, ba za a yi amfani da maganin ba, koda kuwa kwayar sikelin ta motsa. Wannan na iya nuna cewa allura ta toshe ko ta lalace.

Bayani mai mahimmanci. Kafin kowane allura, dole ne a bincika abincin insulin. Idan mara lafiya bai duba yawan insulin ba, to ba zai iya yin isasshen kashi na insulin ba ko kadan, wanda hakan na iya haifar da yawan zubar da jini a cikin jini.

III. Sashi saiti

J. Kafin fara allura, ka tabbata cewa an saita allurar ta “0”. “0” yakamata ya kasance a gaban mai nuna alamar. Juya da mai zaɓin sashi don saita gwargwado wanda likita ya umarta.

Matsakaicin adadin da mai haƙuri zai iya saitawa shine 80 ko 160 IU (don Tresiba ® FlexTouch I 100 IU / ml da Tresiba ® FlexTouch ® 200 IU / ml, bi da bi).

Idan an saita kashi mara daidai, mai haƙuri na iya juyawa mai zaɓin sashi gaba ko baya har sai an saita madaidaicin kashi.

Mai zabar kashi yana saita adadin raka'a. Kawai kanshin kashi da alamomin sutura yana nuna adadin raka'a insulin a cikin maganin da kuka ɗauka.

Matsakaicin adadin da mai haƙuri zai iya saitawa shine 80 ko 160 IU (don Tresiba ® FlexTouch I 100 IU / ml da Tresiba ® FlexTouch ® 200 IU / ml, bi da bi).

Idan ragowar insulin cikin alkairin sirinji ya ƙaranci 80 ko 160 KUDI (don Tresiba ® FlexTouch ® 100 PIECES / ml da Tresiba ® FlexTouch ® 200 PIECES / ml, bi da bi), teburin siyarwar zai tsaya a adadin rakarorin insulin ɗin da suka ragu cikin alkalami.

Duk lokacin da aka zaɓi mai zaɓin kashi, ana jin maɗaukaki, sautin maɓallin ya dogara ne akan ɗan zaɓin sashin da mai zaɓin yake juyawa (gaba, baya ko kuma idan adadin da aka tara ya wuce adadin ɓangarorin insulin wanda ya saura cikin alkairin sirinji). Wadannan latsawa bai kamata a kirga su ba.

Bayani mai mahimmanci. Kafin kowane allura, ya zama dole a bincika raka'a nawa na insulin haƙuri ya ci a kan ma'aunin ƙarar da alamomin kashi. Kada a ƙidaya danna maɓallin harafin sirinji. Idan mai haƙuri ya kafa kuma ya gabatar da kashi mara daidai, yawan glucose a cikin jini na iya zama ya yi ƙasa sosai ko yayi ƙasa sosai.

Matsakaicin ma'aunin insulin yana nuna kimanin adadin insulin ɗin da ya saura a alkalami, don haka ba za'a iya amfani da shi don auna sashin insulin ɗin ba.

IV. Gudanar da insulin

K. Sanya allura a karkashin fatarka ta amfani da hanyar allurar da likitan ka ko likitanka suka ba ka. Tabbatar da cewa sashin maganin yana cikin fagen hangen nesa na mai haƙuri. Karku taɓa madaidaicin adadin tare da yatsunsu. Wannan na iya katse allura. Latsa maɓallin farawa gaba ɗaya kuma riƙe shi a wannan matsayin har sai sashin talla ya nuna “0”. "0" yakamata ya zama daidai da mai nuna sakin, yayin da mai haƙuri zai iya jin ko yaji wani dannawa.

Bayan allurar, bar allura a karkashin fata (aƙalla 6 s) don tabbatar da cewa an allurar da insulin ɗin.

L. Cire allurar daga karkashin fata ta cire sirinji sama.

Idan jini ya bayyana a wurin allurar, a hankali a matse auduga zuwa wurin allurar. Karka tausa wurin allurar.

Bayan an gama allurar, mai haƙuri na iya ganin digo na insulin a ƙarshen allura. Wannan al'ada ce kuma baya tasiri ga adadin maganin da aka gudanar dashi.

Bayani mai mahimmanci. Koyaushe bincika ƙulli na kashi don sanin adadin sassan insulin ɗin ana gudanar dasu. Kayan kwatancen zai nuna ainihin adadin raka'a. Kada ƙidaya yawan dannawa akan alƙalin sirinji. Bayan allurar, riƙe maɓallin fara har sai takaddar ta dawo zuwa “0”. Idan kwayar ta rage ya tsaya kafin a nuna “0”, ba a shigar da cikakken insulin na insulin ba, wanda zai iya haifar da yawan glucose a cikin jini.

V. Bayan an gama allurar

M. Sanya maɗaurin amai na sama a ɗakin kwana, saka ƙarshen allura a cikin hula ba tare da taɓa shi ko allura ba.

N. Lokacin da allura ta shiga hula, a hankali saka ƙyallen a allura. Cire allurar kuma ka watsar dashi, kiyaye matakan kiyayewa na kariya.

A. Bayan kowace allura, saka hula a alƙalami don kare insulin da ya ƙunshi daga haɗuwa zuwa haske.

Jefar da allura bayan kowace allura. Wannan yana rage haɗarin kamuwa da cuta, kamuwa da cuta, yaduwar insulin, toshe allura da kuma gabatarwar kashi mara kyau na miyagun ƙwayoyi. Idan allurar ta toshe, mara lafiya ba zai iya yin allurar insulin ba.

A jefa alkalami da aka yi amfani da shi tare da allura wanda aka yanke kamar yadda likitanka, malamin likitancinku, likitan likitanci, ko ƙa'idodi na yankin suka bada shawara.

Bayani mai mahimmanci. Karka taɓa ƙoƙarin mayar da murfin ciki ciki akan allurar. Mai haƙuri na iya yin jijiya.

Bayani mai mahimmanci. Bayan kowace allura, cire kullun allura kuma adana allurar sirinji tare da cire allurar. Wannan yana rage haɗarin kamuwa da cuta, kamuwa da cuta, yaduwar insulin, toshe allura da kuma gabatarwar kashi mara kyau na miyagun ƙwayoyi.

VI. Menene insulin ya rage?

P. Matsayin insulin saura shine yake nuna kimanin adadin insulin da ya saura a alkalami.

R. Don sanin daidai nawa aka rage insulin a cikin alƙalami, dole ne a yi amfani da takaddar ƙwararawa: juya mai zaɓin suturar har sai magungunan ya tsaya. Idan ƙirar tazara ta nuna lamba 80 ko 160 (don Tresiba ® FlexTouch ® 100 IU / ml da Tresiba ® FlexTouch ® 200 IU / ml, bi da bi), wannan yana nuna cewa aƙalla 80 ko 160 IU na insulin ya rage a cikin alƙawirin syringe (na ƙwayoyi Tresiba ® FlexTouch ® 100 PIECES / ml da Tresiba ® FlexTouch ® 200 PIECES / ml, bi da bi). Idan kwayar magungunan ta nuna kasa da 80 ko 160 (don Tresiba ® FlexTouch ® 100 PIECES / ml da Tresiba ® FlexTouch ® 200 PIECES / ml, bi da bi), wannan yana nuna cewa daidai adadin raka'a insulin da aka nuna a kan tebur ya kasance a alƙawarin sirinji allurai.

Juya da mai zaɓin sashi a cikin kishiyar sashi har sai sashin ƙaryar ya nuna “0”.

Idan sauran insulin ɗin a cikin sirinji na syringe bai isa ba don gudanar da cikakken maganin, zaku iya shigar da adadin da ake buƙata a cikin allura biyu ta amfani da alƙaluman sirinji biyu.

Bayani mai mahimmanci. Dole ne a kula yayin ƙididdigar sauran kashin da ake buƙata na insulin.

Idan mai haƙuri yana da shakku, zai fi kyau a allurar da kai kowane ɗayan insulin ta amfani da sabonn alkalami. Idan mara lafiya ya yi kuskure a cikin lissafinsa, zai iya gabatar da isasshen kashi ko wani babban adadin insulin, wanda zai iya haifar da gaskiyar cewa yawan haɗuwar glucose na jini na iya zama mai yawa ko ƙasa.

Kullum ku riƙa ɗaukar alkairin sirinji tare da ku.

Kullum kwa ɗauki alƙalaran sirrin sirinji da sabbin allura koda sun ɓace ko lalacewa.

Kiyaye alkalami mai sirinji da allura su isa ga dukkan mutane, musamman yara.

Kada a taɓa canja wurin alkalami mai haƙuri da allura ga wasu. Wannan na iya haifar da kamuwa da cuta.

Kada a taɓa canja wurin alkalami mai haƙuri da allura ga wasu. Magungunan na iya cutar da lafiyar su.

Yakamata masu kulawa suyi amfani da allura da aka yi amfani dasu tare da yin taka tsantsan don rage haɗarin sandar allura da kamuwa da cuta.

Kula da alkalami

Dole ne a kula da hankali tare da alkalami mai sirinji. Kula da kulawa ko rashin kulawa mai kyau na iya haifar da rashin daidaituwa, wanda zai haifar da matsanancin yawa ko raguwar glucose mai yawa.

Kada ka bar alƙalami a cikin mota ko wani wuri inda zai fallasa shi ga yanayin zafi sosai ko ƙarancin zafi sosai.

Kare alkalami cikin ƙura, datti da kowane nau'in taya.

Kada ku wanke alkalami, kada ku nutsar da shi cikin ruwa ko sanya shi a ciki. Idan ya cancanta, za'a iya tsabtace alkalami tare da daskararren zane mai laushi tare da sabulu mai laushi.

Kar a jefar ko bugi alƙalami a ƙasa mai tauri. Idan mai haƙuri ya sauke alkalami na syringe ko yana shakkar cewa yana aiki da kyau, haɗa sabon allura kuma bincika allurar kafin yin allura.

Kayi yunƙurin sake cika alkalami mai sikirin. Dole ne a zubar da alƙarfan sirinji wofi.

Karka yi ƙoƙarin gyara sirinji da kanka ko ka ware shi.

Mai masana'anta

Maƙeran kuma mai mallakar takardar rajista: Novo Nordisk A / S.

Novo Alle, DK-2880, Bugswerd, Denmark.

Ya kamata a aika da ikirarin mabukaci zuwa adireshin LLC Novo Nordisk: 121614, Moscow, ul. Krylatskaya, 15, na. 41.

Waya: (495) 956-11-32, fax: (495) 956-50-13.

Tresiba ®, FlexTouch ®, NovoFine ® da NovoTvist ® alamun kasuwanci ne masu rijista ta Novo Nordisk A / S, Denmark.