Acetylsalicylic Acid foda

Mai hanawa da enzyme MOR, yana rushe kayan aikin prostaglandin da samar da ATP. Samun mallaka maganin gargajiya da anti-mai kumburi aikiyana hana tarawa countlet plate.

Tasirin analgesic shine saboda duka tsakiya da na waje. Game da yanayin febrile, yana rage yawan zafin jiki ta hanyar yin aiki akan cibiyar thermoregulation.

Takaitawa da adon plateletkazalika thrombosis raguwa saboda iyawar ASA don kawar da kira na thromboxane A2 (TXA 2) a cikin platelet. Yana hana kira prothrombin (coagulation factor II jini) a cikin hanta da - a cikin kashi da ya wuce 6 g / day. - yana ƙaruwa PTV.

Pharmacokinetics

Rashin kayan bayan shan miyagun ƙwayoyi a ciki ya kusan cika. Lokacin rabin rabin ASA wanda ba a canza shi ba bai wuce minti 20 ba. TCmax TAMBAYA a jini jini - 10-20 minti, jimlar salicylate sakamakon metabolism, - daga 0.3 zuwa 2.0 hours.

A hade albumin jihar a cikin plasma kusan 80% acetylsalicylic da salicylic acid. Ayyukan Halittu ya ci gaba koda lokacin da kwayar ta kasance ta hanyar da aka gina mai gina jiki.

Metabolized a cikin hanta. Kodan ya fice. Excretion yana shafar fitsari pH: lokacin da aka sanya acid acid, yana raguwa, kuma lokacin alkama, yana ƙaruwa.

Magungunan Pharmacokinetic sun dogara da girman adadin da aka ɗauka. Cire kayan ba najasa bane. Haka kuma, a cikin yara na shekara ta 1 na rayuwa, idan aka kwatanta da manya, yana ci gaba da hankali.

Alamu don amfani: me yasa allunan acid acetylsalicylic acid suna taimakawa?

Alamu don amfani da acetylsalicylic acid sune:

• febrile cututtuka a cikin cututtuka da mai kumburi,
• rheumatoid amosanin gabbai,
• rheumatism,
• rauni mai rauni myocardiumlalacewa ta hanyar immunopathological dauki,
• ciwo mai raɗaɗi daban-daban asali ciki har da kai da ciwon hakori (haɗe da ciwon kai wanda ya danganta da cututtukan da ke kawar da barasa), haɗin gwiwa da ciwon tsoka, neuralgia, migraines,algomenorrhea.

Hakanan asfirin (ko acetylsalicylic acid) ana amfani dashi azaman prophylactic idan anyi barazanar thrombosis,thromboembolism, IM (a infarction na zuciya an wajabta magunguna don rigakafin sakandare).

Contraindications

Kudin shiga ASA ya shiga cikin:

• Asfirin fuka,
• yayin wuce gona da iri erosive da ulcerative raunuka na narkewa na canal,
• na ciki / na ciki na jini,
• karancin bitamin K,
• hawan jini, hypoprothrombinemia, basur na maganin basur,
• karanci enzyme G6PD,
• saukar karfin jini,
• gazawar koda / hanta
• watsawa aortic
• a lokacin jiyya Methotrexate (idan sati na maganin ya wuce 15 / mg),
• maganin cututtukan amosanin gabbai, gout,
• na ciki (farkon watanni ukun farko da na karshe sune madaidaici contraindications),
• nono,
• rashin damuwa ga ASA / salicylates.

Side effects

Sakamakon sakamako na maganin ASA na iya faruwa ta hanyar:

• tashin zuciya
• gastralgia,
• anorexia
• halayen rashin lafiyan halayen
• zawo
• thrombocytopenia
• erosive da ulcerative raunuka na narkewa na canal,
• na koda da / ko gazawar hanta.

Tare da yin amfani da tsawan lokaci, tinnitus ya bayyana, raunin ji yana raguwa, hangen nesa yana da rauni, farin ciki yana faruwa kuma, lokacin ɗaukar allurai masu yawa, ciwon kai. Hakanan zubar jini shima zai yiwu. hypocoagulationamai karin ƙarfe.

Acetylsalicylic acid, umarnin don amfani (Hanyar da sashi)

A aiki rheumatism An tsara wa marasa lafiya manya daga 5 zuwa 8 g na ASA kowace rana. Ga yaro, ana yin lissafin kashi gwargwadon nauyi. A matsayinka na mai mulkin, ya bambanta daga 100 zuwa 125 mg / kg / rana. Yawan amfani da yawa - 4-5 p. / Ranar.

Makonni 1-2 bayan fara karatun, ana rage kashi ga jariri zuwa 60-70 mg / kg / rana, ga majinyacin da ya balaga, sashi zai zama iri daya. Ci gaba da jiyya har makonni 6.

Dangane da umarnin don amfani da acetylsalicylic acid, ya kamata a dakatar da miyagun ƙwayoyi a hankali na tsawon makonni 1-2.

Acetylsalicylic acid don ciwon kai kuma a matsayin magani don zafin jiki an wajabta shi a cikin ƙananan sashi. Don haka, tare da ciwo mai raɗaɗi da yanayi febrile kashi na 1 na manya ga manya - daga 0.25 zuwa 1 g tare da yawan aikace-aikacen daga 4 zuwa 6 rubles kowace rana.

Ya kamata a tuna cewa a cikin yanayin ciwon kai, ASA yana da tasiri musamman idan zafin yana fusata da karuwa a cikin ICP (matsa lamba na intracranial).

Ga yara, mafi kyawun kashi a lokaci shine 10-15 mg / kg. Yawan aikace-aikacen da yawa - 5 p. / Ranar.

Jiyya kada ta wuce sati 2.

Don gargadi thrombosis da embolism ASA take 2-3 p. / Ranar. 0,5 g kowane. Don haɓaka rheological Properties (na liquefaction) jini ana shan miyagun ƙwayoyi na dogon lokaci a 0.15-0.25 g / rana.

Ga yaro da ya wuce shekara biyar, haihuwa ɗaya tak ce 0.25 g, an ba wa yara masu shekaru huɗu damar bayar da 0.2 g na ASA sau ɗaya, yara masu shekaru biyu - 0.1 g, da shekara ɗaya - 0.05 g.

Haramun ne a baiwa yara ASA daga zazzabi wanda ya tashi a bayansa hoto ko bidiyo mai zagaya yanar gizo da sauri cuta. Magungunan suna aiki akan kwakwalwa guda ɗaya da tsarin hanta kamar wasu ƙwayoyin cuta, kuma a hade tare hoto ko bidiyo mai zagaya yanar gizo da sauri cuta na iya tayar da hankali ga yaroRaunin Reye.

Amfani da ASA a cikin kayan kwalliya

Mashin fuska na Acetylsalicylic acid yana ba ku damar hanzarin cire kumburi, rage kumburi nama, cire redness, cire farfajiya na sel waɗanda suka mutu da kuma tsabtace pores.

Magungunan yana bushe fata sosai kuma yana narkewa sosai cikin mai, wanda ya sa ya dace don amfani dashi azaman magani kuraje: Allunan sun jike da ruwa, aka shafa wa abubuwanda suke motsawa a fuska ko ƙara zuwa abubuwan shafa fuska.

Acetylsalicylic acid daga kuraje yana aiki sosai tare da ruwan lemun tsami ko zuma. Inganci don warware matsalolin fata da abin rufe fuska tare da yumɓu.

Don shirya lemun-asfirin mask, allunan (guda 6) suna sauƙaƙe tare da ruwan 'ya'yan itace da aka matse har sai an sami taro mai kama ɗaya. Sannan an ga maganin a kunne kumburi kuraje kuma ya bar su har sai sun bushe.

An shirya abin rufe fuska tare da zuma kamar haka: allunan (guda 3) an jika su da ruwa, sannan, lokacin da aka narkar da su, aka haɗu da ruwan zuma na 0.5-1 (shayi).

Don shirya murfin yumbu, allunan 6 na ASA da cokali 2 (teaspoon) na farin / shuɗin yumbu ya kamata a haɗe shi da ruwa mai ɗumi.

Yawan abin sama da ya kamata

Yawan abin sama da ya kamata na iya faruwa daga:

• maganin ASA,
• guda gwamnati na sosai m kashi na miyagun ƙwayoyi.

Alamar yawan zubar da jini shine ciwon salicylism, bayyanar cutar malaria, hauhawar jini, tinnitus, tashin zuciya, amai.

Idan akwai wani karin yawan magungunan cutar ta ASA, ya kamata a kai wanda aka cutar a asibiti nan da nan. An wanke cikinsa, suna bayarwa carbon kunnawaduba CBS.

Ya danganta da yanayin WWTP da ma'aunin ruwa da lantarki, ana iya tsara gabatarwar mafita sodium lactate, garin sodium citrate da sodium bicarbonate (azaman jiko).

Idan fitsari pH shine 7.5-8.0, kuma ƙwayar ƙwayar cuta ta salicylates ta wuce 300 mg / l (a cikin yaro) da 500 mg / l (a cikin manya), ana buƙatar kulawa mai zurfi alkaline diuretics.

Tare da tsananin maye maganin hemodialysis, gyara don asarar ruwa, rubutaccen magani.

Haɗa kai

Yana inganta yawan guba bankwana da shirye-shirye,sinadarin valproic, kashiwaSakamakon maganin mahaifa na bakin jini, Digoxin, narcotic analgesics, Triiodothyronine, magungunan sulfa.

Rashin tasiri kamuwa da cuta (potassium-sparing da madauki), maganin rigakafin jini ACE masu hanawawakilai mai hana ruwa a jiki.

Tare da amfani da lokaci daya magungunan antithrombotic, karafarini,kai tsaye anticoagulants yana kara hadarin zub da jini.

GCS yana haɓaka tasirin mai guba na ASA akan ƙwayar mucous na hanjin narkewa, ƙara haɓakawa da rage yawan ƙwayar plasma.

Lokacin amfani dashi a lokaci guda tare da gishiri, Li yana ƙara yawan ƙwayar plasma na Li + ions.

Inganta mai guba sakamako na barasa a kan mucosa na narkewa canal.

Umarni na musamman

Ya kamata a yi amfani da miyagun ƙwayoyi tare da taka tsantsan a cikin mutane da pathologies na kodan da hanta, asma, tare da hauhawar jini, zubar jini a zuciya, yayin jiyya tare da maganin rashin nasara, da kuma cikin mutane masu tarihinerosive da ulcerative raunuka na narkewa kamar jijiyoyi da / ko na ciki / na ciki na jini.

Koda cikin ƙananan allurai, ASA yana rage shakatawa. uric acidcewa a cikin mai saukin kamuwa da marasa lafiya na iya haifar da mummunan hari gout.

Lokacin yin babban allurai na ASA ko buƙatar magani na dogon lokaci tare da miyagun ƙwayoyi, ya zama dole don saka idanu a kai a kai hawan jini Kuma likita zai gan shi.

A matsayin wakili na anti-mai kumburi, yin amfani da ASA a cikin kashi 5-8 g / rana. iyakantacce saboda haɓakar haɗarin halayen masu haɗari daga ƙwayar mahaifa.

Don rage zubar jini yayin aikin tiyata da kuma bayan aikin haihuwa, shan salicylates ana dakatar da kwanaki 5-7 kafin a yi aikin tiyata.

Lokacin shan ASA, ya kamata a tuna cewa za'a iya ɗaukar wannan magani ba zai wuce kwanaki 7 ba tare da tuntuɓar likita ba. A matsayin maganin ASA na antipyretic, an ba shi damar sha bai wuce kwanaki 3 ba.

Chemical Properties na abu

Lokacin da ASA crystallizes, allura mara launi ko polyocra monoclinic tare da ɗanɗano ɗanɗano mai sauƙi ana kafa su. Lu'ulu'u sun tabbata a iska mara nauyi, amma tare da kara zafi, sannu a hankali sunadarai zuwa salicylic da acetic acid.

Abubuwan da ke cikin tsarkakakken sura sune na lu'ulu'u mai farin launi da kusan wari. Bayyanar kamshin acid din alama ce da ke nuni da cewa sinadarin ya fara aiki da sinadarai.

ASA yana fuskantar tashin hankali a ƙarƙashin aikin alkaline bicarbonates, hydrokalides na alkaline, da cikin ruwan zãfi.

ASA ba ta da kyau mai narkewa a ruwa, mai narkewa a cikin chloroform da ether, sauƙin narkewa a cikin 96% ethanol. Rashin daidaituwa na ASA a cikin ruwa / mai watsa shirye-shirye yana da ƙarfi sosai ta hanyar pH: mafi girma alkalinity na sauran ƙarfi, mafi sauƙi abu yana narkewa.

Acetylsalicylic acid-UBF, Asfrovit, Aspinat, Aspivatrin, Azumi Nekstrim, Fluspirin, Taspir, Asfirin

A cikin yara, ASA ba za a iya amfani da shi ba hauhawar jinimai dangantaka da hoto ko bidiyo mai zagaya yanar gizo da sauri cuta, tunda irin wannan haɗin zai iya haifar da haɓaka yanayin rayuwa mai haɗari ga yaro - Raunin Reye.

A cikin jarirai, salicylic acid na iya yin hijira saboda albumin bilirubin da haɓaka ci gaba encephalopathy.

ASA sauƙin shiga cikin dukkanin ruwayewar jiki da kyallen takarda, ciki har da cerebrospinal, synovial da ruwa na ciki.

A gaban edema da kumburi, hanzarin shiga cikin salicylate a cikin haɗin gwiwa yana haɓaka. A mataki na kumburi, ya yi akasin haka, yana rage gudu.

Menene acetylsalicylic acid don abin ratsewa?

ASA magani ne mai inganci don ratayewa, saboda tasirin maganin ƙwayar cuta.

Koyaya, ya kamata a tuna cewa shan ƙwayar ya fi kyau kar a sha barasa, amma kimanin sa'o'i 2 kafin idi. Wannan yana rage haɗarin ilimi. microthrombi A cikin ƙananan tasoshin kwakwalwa da - a sashi - edema nama.

Yi amfani yayin ciki da shayarwa

Acetylsalicylic acid shine contraindicated yayin daukar ciki. Musamman a farkon watanni uku da na ƙarshe na gestation. A farkon matakan, shan miyagun ƙwayoyi na iya ƙara haɗarin haɓakar haɓakar haihuwar haihuwa, a cikin matakan na gaba - jujjujuwar ciki da rauni.

ASA da metabolites dinsu a cikin karamin sun shiga cikin madara. Bayan gudanar da kula da miyagun ƙwayoyi, ba a lura da tasirin sakamako a cikin jarirai ba; saboda haka, a matsayinka na doka, katsewar shayarwa (HB) ba lallai ba ne.

Idan an nuna mace ta magani na dogon lokaci tare da yawan allurai na ASA, to ya zama dole a dakatar da hepatitis B.

Kusan duk sake dubawa game da ASA suna da kyau. Magungunan ba shi da tsada, mai tasiri, yayi nazari sosai, yana da aikace-aikace iri-iri. Allunan suna daidaita kumburi da zazzabi, da yawan ASA a cikin ƙananan allurai yana rage haɗarin rikitarwa na zuciya a cikin marasa lafiya da aka ƙaddara.

Rashin kyawun maganin shine yawanci ana kiransa tasirin sakamako masu illa. Koyaya, kamar yadda yawancin mutane suka lura, don guje musu, ya isa bin wasu ƙa'idodi yayin lokacin magani: aƙalla, kafin shan magungunan, ya kamata a hankali karanta umarnin da dakatar shan shan giya don duk lokacin maganin.

Aikin magunguna

Acetylsalicylic acid shine mai hana steroidal anti-inflammatory magani wanda ke da antipyretic, analgesic, anti-inflammatory, antiaggregatory action hade da hana ayyukan COX1 da COX2 wanda ke tsara tsarin ayyukan prostaglandins. Ressoƙarin kira na thromboxane A2 a platelet, rage haɗuwa, faranti da kuma thrombosis. Bayan gudanar da aikin parenteral na maganin mai ruwa-ruwa, sakamako na analgesic yafi magana sosai fiye da lokacin sarrafa baki na acetylsalicylic acid. Tare da subconjunctival da parabulbar gwamnatin, yana da ƙayyadadden sakamako na anti-mai kumburi, wanda pathogenetically ya tabbatar da yin amfani da miyagun ƙwayoyi don lura da ayyukan kumburi a cikin ido na asali da kuma wurare daban-daban. An bayyana tasirin anti-mai kumburi sosai lokacin amfani da miyagun ƙwayoyi a cikin lokacin lokacin aikin kumburi a cikin ido. Maganin yana rage kwantar da hancin kwayar idanuwa.

Sashi da gudanarwa

Zuwa cikin abubuwan ampoule (vial) tare da 25 MG ko 50 MG na maganin, ƙara 2.5 ml ko 5 ml na ruwa don allura, da bi, kuma girgiza har sai an narkar da gaba ɗaya. Ana amfani da maganin 1% kawai na maganin acetylsalicylic acid.

Subconjunctival ko parabulbar a cikin sashin da basu wuce 0.5 ml na maganin 1% yau da kullun ko kowace rana. Ana iya amfani da maganin 1% a cikin nau'i na shigarwa na 12 saukad da har zuwa sau 3-4 a rana.

A cikin lura da matakai na kumburi a cikin ido, ana amfani da maganin 1% a cikin nau'ikan shigarwa, 2 saukad da sau 3-4 a rana.

A cikin jiyya na endogenous da exogenous uveitis na kowane etiology, ana shirya maganin 1% wanda aka shirya sauƙaƙe cikin girman 0.5 ml sau ɗaya a rana har sai an tsayar da kumburi. Aikin magani shine kwanaki 3-10. Ya danganta da tsananin zafin kumburin, ana iya haɗa subconjunctival management tare da shigarwa na miyagun ƙwayoyi 1-2 saukad da maganin 1% har zuwa sau 5 a rana. Idan akwai lamuran sassauci, mutum zai iya iyakantar da kansa kawai zuwa saukad da 1-2 na 1% na sau 3-4 a rana.

Yin rigakafi da lura da rikicewar ciki da rikice-rikice na wucin gadi 1% ana gudanar da subconjunctival ko parabulbar a cikin yawan 0.3-0.5 ml sau ɗaya a rana. Hanyar magani shine allurar 9-10.

Yin rigakafin cututtukan macular bayan ayyukan da suka shafi cirewar cataract da kuma shigar da ruwan tabarau na wucin gadi, ana amfani da maganin da aka shirya a cikin nau'ikan shigarwa na 1% bayani, 1-2 saukad da sau 3-4 a rana don makonni 4 bayan hakar cataract.

Side sakamako

Tare da yin amfani da magani na ganyayyaki a cikin hanyoyin da aka bada shawara na magunguna, ana haifar da sakamako masu illa.

Tare da gudanarwar subconjunctival, bayyanar chemosis mai yiwuwa ne, wanda ke warwarewa a cikin 'yan awanni. Sirrin jiki da azanci mai jiyuwa a cikin allurar ana bayyanasu cikin dan lokaci, tsawon lokacin abin mamakin shine minti 5-7. Don rigakafin ciwo tare da subconjunctival ko gudanarwar parabulbar, an ba shi izinin amfani da maganin 2% na procaine a matsayin abu mai ƙarfi a cikin shirye-shiryen maganin acetylsalicylic acid.

Wasu lokuta a cikin allurar, za'a iya samun ƙwanƙwasa nama, zubar jini na subconjunctival, wanda aka cire shi ta hanyar amfani da sinadarin iodide 3% na iodide a cikin kayan shigarwa sau 4-5 a rana.

Wataƙila, haɓakar tashin zuciya, asarar ci, gudawa, ciwace-ciwacen kumburi da zubar jinni a cikin narkewar abinci, halayen ƙwayar cuta (fatar fata, angioedema), hanta da / ko gazawar koda, thrombocytopenia, bronchospasm.

Siffofin aikace-aikace

Ya kamata a yi amfani da mafita da aka yi da rana. Kada ku haɗa maganin allura na miyagun ƙwayoyi tare da mafita daga wasu magunguna waɗanda ba a lissafta su cikin wannan umarnin ba. Pharmaceutically ya dace da procaine (a cikin sirinji ɗaya). Idan ya zama dole don rubanya acetylsalicylic acid a lokaci guda tare da sauran magunguna don etiotropic da / ko Symptomatic therapy, aƙalla mintuna 10-15 ya kamata yai tsaka tsakanin amfani da jami'ai iri-iri. Hanyar magani kada ta wuce kwanaki 10-12. A yayin jiyya, kar a taɓa sa ruwan tabarau.

Don rigakafin rikice-rikice na cututtukan cututtukan ƙwayar cuta (musamman a cikin marasa lafiya da masu ciwon sukari mellitus), ana bada shawarar yin amfani da farkon angioprotectors (dicinone, etamsylate, da sauransu).

Kariya da aminci

Yin amfani da miyagun ƙwayoyi yana buƙatar taka tsantsan idan akwai matsala a cikin tsarin coagulation na jini da cututtukan jijiyoyi da cututtukan ƙwayar jijiyoyin ƙwayar hanji a cikin anamnesis saboda yiwuwar zub da jini. Tare da raunuka na ido mai lalacewa tare da lalacewar jikin ciliary, zubar jini yana yiwuwa.

Acetylsalicylic acid ko da a cikin ƙananan allurai yana rage haɗarin uric acid daga jikin mutum, wanda zai iya haifar da haɓakar mummunan gout a cikin marasa lafiya mai saurin kamuwa. A lokacin magani ya kamata ya guji shan ethanol.

Tasiri kan ikon tuka motoci da sarrafa hanyoyin da ke da haɗari: marasa lafiyar da ke rasa bayyananniyar hangen nesa na ɗan lokaci bayan amfani da ƙurawar ido ba a ba da shawarar su fitar da motocin ko yin aiki tare da hanyoyin motsa jiki na mintina kaɗan bayan ƙaddamar da maganin.

Sunan kasa da kasa mai zaman kansa

INN: Acetylsalicylic acid.

Asfirin foda magani ne na duniya don sauƙaƙa alamun bayyanar cututtuka na yau da kullun da mura.

Foda a cikin abun da ke ciki yana da adadin mahadi dayawa lokaci daya. Daga cikinsu: Acetylsalicylic acid 500 MG, chlorpheniramine da phenylephrine. Componentsarin abubuwan haɗin sune: sodium bicarbonate, ƙaramin adadin citric acid, dandano lemun tsami da launin rawaya.

Foda a cikin nau'i na ƙananan granules. Kusan koyaushe yana da farin launi, wani lokacin tare da launin rawaya. Effervescent foda an yi niyya don shiri na mafita. Sanya cikin takaddun takaddara na musamman da aka sanya.

Effervescent foda an yi niyya don shiri na mafita.

Abinda ke taimakawa Aspirin foda

Ana amfani da Aspirin Complex (asfirin hadaddun) azaman daya daga cikin masu amfani da cututtukan cututtukan cututtukan daji don kawar da alamun cutar. Sakamakonsa an barata ne saboda hadadden kayan aikin da ke kunshe a cikin foda.

Babban alamomi don amfani:

• lura da ciwon hakori da ciwon kai,
• myalgia da arthralgia,
• ciwon makogwaro
• hadadden far a lura da babba na numfashi fili cututtuka,
• zafin ciki
• tsananin ciwon baya
• zazzabi da zazzabi, ya bayyana a cikin sanyi da sauran cututtukan cututtukan da ke tattare da yanayin rashin ƙarfi.

Wadannan alamomin an yi su ne ga manya da yara sama da 15. Amma sashi da tsawon lokacin jiyya an ƙaddara daban-daban ga kowane mara lafiya, gwargwadon yanayin tsananin alamun bayyanuwar asibiti.