Kwayoyi masu kare rigakafi sun daɗe cikin kunshe cikin rayuwar ɗan adam. Yanzu zaku iya samun magungunan rigakafi, sabulu mai kashe ƙwayoyin cuta, gel na kwayan cuta ko goge, da sauransu. Amma yi amfani da duk hanyoyi sosai a hankali. Musamman idan yazo batun magunguna. Labarin yau zai ba ku labarin menene Gentamicin-Akos. Don abin da ake amfani da maganin shafawa, kuma a cikin wane yanayi ne mafi kyawun ƙin karɓar shi, za ku ƙara koya.

Pharmacokinetics

Bayan aikace-aikacen, samfurin kusan ba'a ɗaukar su a waje. Magunguna yana aiki da sauri akan shafin kumburi ko rauni.

Bayan gudanar da intramuscularly, abu mai aiki yana ɗaukar hanzari. Excretion yana tare da fitsari da bile. Yana ɗaure kaɗan ga furotin jini na jini.

Za'a iya ɗaukar shayin idanu kamar marasa ƙima.

Contraindications

Ba a da maganin shafawa don dalilai na warkewa idan mutum yana da haɓaka mai haɓaka zuwa ɓangaren miyagun ƙwayoyi (gami da tarihi) ko aminoglycosides, uremia, auditory jijiya neuritis, mahimmancin ƙwayar cutar na yara.

Ana amfani da Gentamicin Akos wajen maganin cututtukan idanu na ƙwayar cuta.

Pharmacodynamics

Yana ɗaure zuwa sashin 30S na ribosomes kuma ya lalata tsarin furotin, yana hana haɓaka hadaddun abubuwan sufuri da manzon RNA, kuma an killace lambar ƙwaƙwalwar ba daidai ba kuma an samar da sunadarai marasa aiki. A cikin babban taro, yana warware aikin shinge na membrane na cytoplasmic kuma yana haifar da mutuwar ƙananan ƙwayoyin cuta.

Inganci da yawa gram-tabbatacce kuma gram-korau kwayoyin. Tsarin ƙwayoyin cuta na ƙwayar cuta na gram-korau - Proteus spp. Suna da matukar ladabi ga Gentamicin (MPC ƙasa da 4 mg / l). (gami da indole-tabbatacce kuma indole-korau iri), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp., micromgangan na gram-tabbatacce - Staphylococcus spp. (ciki har da penicillin-resistant), mai hankali tare da MPC 4-8 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. (gami da Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. Resistant (MPC fiye da 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Streptococcus spp. (gami da cututtukan huhu da ƙwayoyin cuta na rukunin D), Bacteroides spp., Clostridium spp., Providencia rettgeri. A hade tare da penicillins (ciki har da benzylpenicillin, ampicillin, carbenicillin, oxacillin), aiki akan kira na bangon tantanin halitta, yana aiki da Enterococcus faecalis, Enterococcus durans, Enterococcus durans, Enterococcus faiumium da kusan All iri (ciki har da Streptococcus faecalis liguifaciens, Streptococcus faecalis zymogenes), Streptococcus faecium, Streptococcus durans. Juriyar kwayar halittar kananan ƙwayoyin cuta zuwa Gentamicin tana haɓaka sannu a hankali, duk da haka, nau'in da ke tsayayya da neomycin da kanamycin na iya nuna juriya ga jigon maganin (mara ƙoshin giciye). Ba ya shafar anaerobes, fungi, ƙwayoyin cuta, protozoa.

Yawan abin sama da ya kamata

Bayyanar cututtuka: rage ƙwayar jijiyar ƙwayar jijiya (kamawar numfashi).

Jiyya: an gabatar da magungunan anti-cholinesterase (Proserinum) da shirye-shiryen alli (5-10 ml na maganin 10% na alli chloride, 5-10 ml na maganin 10% na alli gluconate) a cikin manya. Kafin gabatarwar Prozerin, atropine a cikin kashi na 0.5-0.7 mg ana fara aiwatar da iv, ana tsammanin karuwar bugun jini, kuma 1.5-2 min daga baya, 1.5 MG (3 ml na 0.05% bayani) ana allurar. Idan sakamakon wannan kashi bai wadatar ba, ana sake sarrafa maganin guda ɗaya na Prozerin (tare da bayyanar bradycardia, an ba da ƙarin allurar atropine). Ana bai wa yara abinci mai ƙwaro. A cikin mummunan yanayi na rashin damuwa na numfashi, ana buƙatar samun iska ta injin. Ana iya fitar dashi ta hanyar hemodialysis (mafi inganci) da kuma maganin bugun jini na ciki.