Rinsulin® NPH (Rinsulin NPH)

Sunan duniya: Rinsulin r

Abun ciki da nau'i na saki

Maganin maganin allura abu ne mara kyau, mara launi. 1 ml ya ƙunshi 100 IU na narkewa na ininiyan ɗan adam mai narkewa. Fitowa: metacresol - 3 MG, glycerol - 16 MG, ruwa d / i - har zuwa 1 ml.

Ofarar kwalban ita ce 10 ml. An cushe a cikin akwatin kwali.

Mountedarar da katako ta saka a cikin sirinji mai yawa, alkalami, 3 ml. Akwai katako guda 5 a kowane fakiti.

Clinical da kungiyar magunguna

Short-aiki insulin mutum

Rukunin Magunguna

Short insulin

Maganin magunguna na Rinsulin R

'Insulin' ɗan adam da ke yin gajeran aiki ta hanyar amfani da fasahar DNA. Yana hulɗa tare da takamaiman mai karɓa a kan ƙwayar cytoplasmic na sel na jikin mutum kuma yana samar da hadaddun insulin-receptor wanda ke motsa ayyukan cikin ciki, gami da kira na enzymes masu yawa (hexokinase, pyruvate kinase, glycogen synthetase). Rage glucose na jini yana faruwa ne saboda karuwa a cikin jijiyoyin zuciya, ƙaddamar da haɓakawa da karɓar ƙwayoyin cuta, haɓakar lipogenesis, glycogenogenesis, da raguwa a cikin yawan samar da glucose ta hanta.

Tsawon lokacin aiwatar da shirye-shiryen insulin ya kasance ne sabili da yawan rashi, wanda ya dogara da abubuwa da yawa (alal misali, akan kashi, hanyar da wurin gudanarwar), sabili da haka bayanin aikin insulin yana haifar da sauyawa sosai, duka mutane daban-daban kuma iri daya mutum.

Matsakaicin, bayan sc gwamnati, miyagun ƙwayoyi sun fara aiki bayan minti 30, matsakaicin sakamako yana haɓaka tsakanin 1 hour zuwa 3, tsawon lokacin aikin shine 8 hours.

Pharmacokinetics

Cikakken mamayewa da farawar insulin ya dogara da hanyar gudanarwa (s / c, i / m), wurin allurar (ciki, cinya, gindi), kashi (yawan insulin insulin), da kuma tattarawar insulin a cikin shiri.

An rarraba shi ba tare da daidaituwa ba tsakanin kyallen takarda, baya shiga cikin shinge na mahaifa kuma zuwa cikin madara.

Metabolism da excretion

An lalata shi ta hanyar insulinase galibi a cikin hanta da kodan. T 1/2 'yan mintuna ne. Kodan ya fitar da ita (kashi 30-80%).

Nau'in 1 na ciwon sukari mellitus, nau'in ciwon sukari na 2 na ciwon sukari: mataki na tsayayya da maganin cututtukan mahaifa, wani bangare na jigilar magunguna na baki (hadewar hankali), ciwon suga, ketoacidotic da hyperosmolar coma, ciwon sukari mellitus wanda ya faru a lokacin daukar ciki (idan ba shi da tasiri ga maganin rage cin abinci) Amfani da kai tsaye a cikin marasa lafiya da masu ciwon sukari mellitus da cututtuka tare da zazzabi mai zafi, tare da aikin tiyata mai zuwa, raunin da ya faru, haihuwa, tare da cin zarafi game da ene abubuwa kafin a ci gaba zuwa jiyya tsawo insulin shirye-shirye.

Contraindications Rinsulin P

Hypoglycemia, ƙara yawan hankalin mutum ga insulin ko kowane ɓangaren magunguna.

Sashi da tsarin da hanyar aikace-aikace Rinsulin P

Magungunan an yi nufin ne don SC, a / m da / a cikin gabatarwar. Matsayi da hanyar gudanar da magunguna an ƙaddara ta likita daban-daban a cikin kowane yanayi, dangane da tattarawar glucose a cikin jini.

A matsakaici, kashi na yau da kullum na miyagun ƙwayoyi ya tashi daga 0.5 zuwa 1 IU / kg nauyin jikin mutum (ya dogara da yanayin halayen mutum na haƙuri da haɗuwa da glucose jini).

Zazzabi na insulin allurar ya dace da zazzabi dakin.

Ana gudanar da maganin a cikin mintina 30 kafin cin abinci ko abun ciye-ciye wanda ya ƙunshi carbohydrates.

Tare da monotherapy tare da miyagun ƙwayoyi, yawan gudanarwa shine sau 3 / rana (idan ya cancanta, 5-6 sau / rana). A cikin adadin yau da kullun ya wuce 0.6 IU / kg, ya zama dole don shiga cikin nau'in 2 ko fiye da injections a cikin bangarori daban-daban na jiki.

Yawancin lokaci ana yin magani ne zuwa bangon ciki na ciki. Hakanan za'a iya yin allura a cinya, gindi, ko kuma yanki na ƙwayar tsoka ta kafada. Wajibi ne don canja wurin allurar a cikin yankin na jikin mutum don hana haɓakar lipodystrophy.

Tare da kulawar s / c na insulin, dole ne a kula da kar a shigar da bututun jini yayin allura. Bayan allurar, bai kamata a sanyaya wurin da allura ba. Yakamata a horar da marassa lafiya yadda yakamata ayi amfani da na’urar insulin.

Ana iya gudanar da magani na IM da IV kawai a ƙarƙashin kulawa na likita.

Rinsulin ® P shine insulin aiki gajere kuma yawanci ana amfani dashi a hade tare da insulin na matsakaici (Rinsulin ® NPH).

Ka’idojin gudanar da magunguna

Ba za ku iya amfani da miyagun ƙwayoyi ba idan hazo ya bayyana a cikin mafita.

Lokacin amfani da insulin guda ɗaya kaɗai

1. Sanitize robar roba ta vial.

2. Zana iska a cikin sirinji a cikin adadin wanda yayi daidai da adadin insulin da ake buƙata. Sanya iska a cikin murfin insulin.

3. Juya murfin tare da sirinji a sama kuma zana adadin insulin da ake so a cikin sirinji. Cire allura daga vial kuma cire iska daga sirinji. Bincika daidai da adadin insulin.

4. Cike kai tsaye.

Idan kana buƙatar haɗa nau'ikan insulin guda biyu

1. Sanki da roba na roba.

2. Nan da nan kafin yin bugun, sai a mirgine kwalban insulin aiki (“gajimare”) tsakanin tafin hannunka har lokacin insulin ta zama fari da gajimare.

3. Zuba iska a cikin sirinji a cikin adadin wanda yayi daidai da kashi na insulin girgije. Sanya iska a cikin vial insulin mai girgije kuma cire allura daga cikin vial.

4. Don jawo iska zuwa cikin sirinji a cikin girman yayi daidai da matakin insulin gajeriyar aiki ("m"). Introduaddamar da iska a cikin murfin 'insulin' 'gaskiya'. Juya kwalban tare da sirinji a sama ya tattara kashi da ake buƙata na insulin “m”. Cire allura kuma cire iska daga sirinji. Bincika daidai gwargwado.

5. Saka allura a cikin murfin tare da insulin '' hadari '', kunna murfin tare da sirinji a gefe kuma tattara gwargwadon insulin ɗin da ake so. Cire iska daga sirinji ka bincika ko kaɗaicin yayi daidai. Magani allura daga cikin cakuda insulin nan da nan.

6. Ya kamata koyaushe ku rubuta insulins a cikin jeri ɗaya kamar yadda aka bayyana a sama.

Wajibi ne don magance yankin fata inda za a allurar da insulin.

Tare da yatsunsu guda biyu, tara fatar fata, saka allura a cikin gindin murfin a kwana na kusan 45 ° kuma a saka allurar a ƙarƙashin fata.

Bayan allura, ya kamata a bar allurar a karkashin fata na akalla a kalla 6 don tabbatar da cewa an saka insulin a ciki.

Idan jini ya fito a wurin allurar bayan cire allura, a hankali danna wurin allura tare da swab moistened tare da maganin mafitsara (alal misali, barasa).

Wajibi ne don canja wurin allurar.

Side effects

Side sakamakosaboda tasirin metabolism: yanayin hypoglycemic (pallor na fata, karuwar gumi, palpitations, rawar jiki, jin sanyi, yunwar, tashin hankali, paresthesia na mucosa na baka, ciwon kai, tsananin farin ciki, raguwar iskar gani). Mai tsananin rashin ƙarfi na hypoglycemia na iya haifar da haɓakar ƙwaƙwalwar ƙwayar cuta.

Allergic halayen: fata mai rauni, ƙurawar Quincke, girgiza ƙwayar cuta anaphylactic.

Ayyukan gida hyperemia, kumburi da itching a wurin allura, tare da tsawan amfani - lipodystrophy a wurin allurar.

Sauran: kumburi, raguwa na ɗan lokaci a yanayin gani na gani (galibi a farkon farfajiya).

Ya kamata a sanar da mara lafiya cewa idan ya lura da ci gaban hypoglycemia ko kuma wani lamari na asarar hankali, ya kamata ya sanar da likita nan da nan.

Idan aka gano wasu cututtukan da ba a bayyana a sama ba, mai haƙuri kuma yakamata ya nemi likita.

Haihuwa da lactation

Babu ƙuntatawa game da lura da ciwon sukari mellitus tare da insulin yayin daukar ciki, saboda insulin baya ƙetare shingen ƙarfe. Lokacin da ake shirin daukar ciki da lokacin sa, ya zama dole a kara yin maganin cutar sankara. Bukatar insulin yawanci yana raguwa a farkon farkon ciki kuma sannu a hankali yana ƙaruwa a cikin na biyu da na uku.

Lokacin kuma kai tsaye bayan haihuwa, buƙatun insulin na iya raguwa kwatsam. Jim kaɗan bayan haihuwa, buƙatar insulin da sauri ya koma matakin da ya kasance kafin yin juna biyu. Babu ƙuntatawa game da lura da ciwon sukari mellitus tare da insulin yayin shayarwa. Koyaya, yana iya zama mahimmanci don rage adadin insulin, sabili da haka, saka idanu a hankali na watanni da yawa ya zama dole kafin a inganta buƙatar insulin.

Aikace-aikacen don aikin hanta mai rauni Matsakaicin insulin dole ne a gyara don aikin hanta mai lalacewa .. Yi amfani da shi don aiki na keɓaɓɓiyar aiki Dole a yi amfani da kashi na insulin don aikin nakasa mai rauni.

Yi amfani da shi a cikin tsofaffi marasa lafiya

Yawan adadin insulin dole ne a gyara don masu ciwon sukari a cikin marasa lafiyar da suka girmi shekaru 65.

Umarnin na musamman don shigarwa Rinsulin P

A waje da tushen ilimin insulin, kulawa akai-akai na maida hankali kan glucose jini yana da muhimmanci.

Baya ga yawan shan insulin, abubuwan da ke haifar da rashin ƙarfi a cikin jiki na iya haɗawa da maye gurbin miyagun ƙwayoyi, tsallake abinci, amai, gudawa, haɓaka aiki na jiki, cututtukan da ke rage buƙatar insulin (lalacewar hanta da ƙwaƙwalwar hanji, hauhawar jijiyoyi, ƙwayar ƙwayar cuta ko glandar thyroid), da kuma canji a wurin allurar, da kuma hulɗa tare da wasu kwayoyi.

Dolle ba daidai ba ko katsewa a cikin aikin insulin, musamman a cikin marasa lafiya da ke dauke da ciwon sukari na 1, na iya haifar da cutar hauka. Yawancin lokaci, alamun farko na hyperglycemia suna haɓaka hankali a kan sa'o'i da yawa ko kwanaki. Waɗannan sun haɗa da ƙishirwa, yawan urination, tashin zuciya, amai, amai, ja, bushewar fata, bushewar baki, rashin ci, kamshin acetone a cikin iska mai ƙuna. Idan ba a kula da shi ba, zazzabin hyperglycemia a cikin nau'in 1 na ciwon sukari na iya haifar da haɓakar cutar ketoacidosis mai barazanar rayuwa.

Yawan maganin insulin dole ne a gyara shi saboda aikin thyroid mai rauni, cututtukan Addison, cututtukan zuciya, hanta da aikin koda, da kuma cututtukan sukari a cikin marasa lafiya da suka haura shekaru 65.

Idan mai haƙuri ya ƙara yawan motsa jiki ko ya canza abincin da aka saba, ana buƙatar daidaita sashin insulin.

Juyawa daga wani nau'in insulin zuwa wani yakamata a gudanar dashi karkashin kulawar tattarawar glucose a cikin jini.

Magungunan yana rage haƙuri haƙuri.

Sakamakon yiwuwar hazo a cikin wasu catheters, ba a bada shawarar yin amfani da miyagun ƙwayoyi a cikin farashin matatun.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Dangane da babban dalilin insulin, canji a nau'ikansa ko kasancewar mahimman damuwa na jiki ko na tunani, yana yiwuwa a rage ikon hawa mota ko sarrafa abubuwa daban-daban, kazalika da shiga cikin wasu ayyukan masu haɗari waɗanda ke buƙatar haɓakar hankali da saurin halayen tunani da na motsi.

Yawan abin sama da ya kamata

Tare da yawan yawan zubar da ruwa, ƙwanƙwasa jini na iya haɓaka.

Jiyya: mai haƙuri na iya kawar da ɗimbin ƙwayar cuta mai narkewa ta hanyar shan sukari ko abinci mai-carbohydrate. Sabili da haka, an ba da shawarar ga marasa lafiya masu ciwon sukari don ɗaukar sukari, Sweets, cookies ko ruwan 'ya'yan itace mai dadi tare da su.

A cikin lokuta masu tsauri, lokacin da mara lafiya ya rasa hankali, ana gudanar da maganin 40% na dextrose (glucose) iv, i / m, s / c, iv glucagon. Bayan ya dawo da hankali, ana ba da shawarar mai haƙuri ya ci abinci mai arzikin carbohydrate don hana sake haɓakar ƙwanƙwasa jini.

Haɗi tare da Sauran Magunguna

Magunguna ba tare da maganin wasu magunguna ba. Tasirin hypoglycemic yana haɓaka ta hanyar sulfonamides (gami da magungunan maganin hypoglycemic na baka, sulfonamides), MAO inhibitors (ciki har da furazolidone, procarbazine, selegiline), inhibitors na carbonic anhydrase inhibitors, ACE inhibitors, ACE inhibitors, NSAIDs (gami da salicylates), anabolic (ciki har da stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, phenfluramine, Li + shirye-shirye, pyridoxine, quinidine, quinine, chloroquin Hypoglycemic effects na sosai glucagon, girma hormone, corticosteroids, na baka hana, estrogens, thiazide da madauki diuretics, BCCI, thyroid hormones, heparin, sulfinpyrazone, sympathomimetics, danazol, tricyclics, clonidine, alli antagonists, diazoxide, morphine, marijuana, nicotine, phenytoin, epinephrine, H1-histamine mai hana masu tallatawa. Beta-blockers, reserpine, octreotide, pentamidine zasu iya haɓakawa da raunana tasirin hypoglycemic na insulin.

Sharuɗɗan hutu na kantin

Magungunan magani ne.

Sharuɗɗan da yanayin ajiya Rinsulin P

Ya kamata a adana miyagun ƙwayoyi daga isar yara, a kiyaye shi daga haske, a zazzabi na 2 ° zuwa 8 ° C, kada a daskare. Rayuwar shelf shine shekaru 2.

Yin amfani da miyagun ƙwayoyi Rinsulin r kawai kamar yadda likita ya umarta, an ba da bayanin don tunani!

Tsarin ilimin rayuwa (ICD-10)

Sashi da gudanarwa

An sanya maganin ciki ta hanyar magunguna Rinsulin ® NPH.

Ana amfani da maganin ne ta hanyar likita kwata-kwata a kowane yanayi dangane da tattarawar glucose a cikin jini. A matsakaici, kashi na yau da kullum na miyagun ƙwayoyi ya tashi daga 0.5 zuwa 1 IU / kg (dangane da halayen mutum na mai haƙuri da haɗuwa da glucose a cikin jini).

Tsofaffi marasa lafiya da ke amfani da kowane insulin, gami da Rinsulin ® NPH, suna cikin haɗarin haɗarin hauhawar jini sakamakon kasancewar haɗuwar cututtukan cututtukan cuta da karɓar lokaci guda na kwayoyi da yawa. Wannan na iya sanya ya zama dole don daidaita sashin insulin.

Marasa lafiya da ke fama da rauni koda kuma aikin hepatic suna cikin haɗarin hauhawar jini kuma yana iya buƙatar ƙarin gyare-gyare na sashin insulin akai-akai da kuma sa ido akai-akai na glucose jini.

Zazzabi na insulin da ke cikin yakamata ya zama zazzabi a dakin. Yawancin lokaci ana amfani da maganin a cikin cinya. Hakanan za'a iya yin allurar a cikin bango na ciki na ciki, gindi ko kuma yanki kafada a cikin tsinkayar tsoka mai narkewa. Wajibi ne a canza wurin allurar a cikin yankin na jiki don hana ci gaban lipodystrophy.

Tare da kulawar s / c na insulin, dole ne a kula da kar a shigar da bututun jini yayin allura. Bayan allurar, bai kamata a sanyaya wurin da allura ba. Yakamata a horar da marassa lafiya yadda yakamata ayi amfani da na’urar insulin.

Kafin amfani da shi, ya kamata a birgine kwandunan Rinsulin ® NPH tsakanin tafin hannu a cikin wani wuri a kwance 10 kuma ya girgiza don sake farfado da insulin har sai ya zama ruwan ɗimbin ruwan madara ko madara. Bai kamata a kyale farji ya faru ba, wanda na iya tsoma baki tare da madaidaicin kashi.

Ya kamata a bincika zane-zane a hankali. Kada kuyi amfani da insulin idan ya ƙunshi flakes bayan haɗuwa, farin barbashi mai laushi yana riƙe da tushe ko ganuwar katun, yana ba da bayyanar mai mai daskarewa.

Na'urar katuwar katako ba ta bada izinin haɗa abubuwan da ke cikin su tare da wasu abubuwan insulins kai tsaye a cikin katun da kanta.Ba a cika cika abubuwan alaƙar katako ba.

Lokacin amfani da katako tare da alkalami mai warware warkarwa, umarnin mai siyayya don cika kwas ɗin cikin alƙalin syringe kuma yana ɗaukar allura ya kamata a bi. Ya kamata a gudanar da miyagun ƙwayoyi daidai da umarnin mai sana'anta don alkalami mai sikari.

Bayan an saka shi, ya zama dole a cire allurar ta hanyar amfani da mabulen wankin na allura kuma a hallaka shi nan take. Cire allurar kai tsaye bayan allura na tabbatar da tsawan jiki, yana hana jijiyoyin jiki, yaduwar iska da kuma yiwuwar rufe allurar. Sannan sanya hula a hannu.

Lokacin amfani da allon da za'a iya amfani dashi da yawa, ya zama dole a haɗu da dakatarwar Rinsulin ® NPH a cikin maɓallin sirinji nan da nan kafin amfani. Haɗin da aka haɗu da kyau ya kamata ya zama fari da gajimare.

Ba za a iya amfani da Rinsulin ® NPH a cikin alkalami ba idan ya kasance mai daskarewa. Lokacin amfani da pre-cika maganin da za'a iya amfani da allunan sirinji na allura don maimaita injections, yana da buqatar ka cire alkairin sirinji daga firiji kafin amfani na farko kuma bari likitan ya isa zafin jiki a ɗakin. Dole a bi takamaiman umarnin don amfani da alkairin da aka bayar tare da miyagun ƙwayoyi.

Rinsulin ® NPH a cikin alkairin sirinji da allura an yi niyya ne don amfanin mutum kawai. Kar a cika kwantar da sikirin.

Kada a sake amfani da allura

Don karewa daga haske, ya kamata a rufe alƙarin sirinji tare da hula.

Karku ajiye firinjin da aka yi amfani dashi a cikin firiji.

Ana iya gudanar da Rinsulin can NPH ko dai daban-daban ko kuma a hade tare da insulin-ɗan gajeran aiki (Rinsulin ® P).

Adana miyagun ƙwayoyi a amfani da zazzabi a daki (daga 15 zuwa 25 ° C) na tsawan kwanaki 28.

Amfani da katako ta amfani da alkawuran sirinji mai amfani

Za a iya amfani da ridararrakin katako tare da Rinsulin ® NPH tare da allon alkawuran da za'a sake amfani dashi:

- sirinjina alkalami Avtopen Classic (Tsararren Autopen 3 ml 1 Rukunin (1-2 raka'a) AN3810, Kyaftin Autopen 3 ml 2 Unit (2-42 raka'a) AN3800) masana'antar Owen Mumford Ltd, United Kingdom,

- alkalami a cikin allurar rigakafi don gudanar da insulin HumaPen ® Ergo II, HumaPen ® Luxura da HumaPen ® Savvio wanda "Eli Lilly da kamfani / Eli Lilly da Comranu", Amurka,

- insulin ta sirinji OptiPen ® Pro 1 wanda kamfanin Aventis Pharma Deutschland GmbH / Aventis Pharma Deutschland GmbH ke yi, Germany,

- sirinji alkalami BiomaticPen by wanda Ipsomed AG / Ypsomed AG, Switzerland,

- pen-injector don gabatarwar insulin mutum RinsaPen I samar "Ipsomed AG / Ypsomed AG", Switzerland.

A hankali bi umarnin don amfani da sirinji alkawuran da masana'anta suka bayar.

Fom ɗin saki

Dakatarwa don gudanarwar subcutaneous, 100 IU / ml.

3 ml na miyagun ƙwayoyi a cikin gilashin gilashin tare da maɓallin roba wanda aka yi da roba, an yi birgima a cikin haɗin da aka haɗa tare da aluminium tare da diski na roba.

Kwallan gilashi tare da daskararren farfajiya an saka shi cikin kowane kicin.

1. Karanti guda biyar ana sanya su cikin buhunan firiji mai walƙiya da aka yi da fim ɗin PVC da fitila na aluminium. An sanya murfin furen bakin 1 a cikin fakitin kwali.

2. Katin da aka saka a cikin takaddun sirinji mai-yawan diski na filastik don maimaita alluran Rinastra ® ko Rinastra ® II. 5 an cika alkawuran sirinji tare da umarnin yin amfani da alkairin sirinji a cikin fakitin kwali.

10 ml na miyagun ƙwayoyi a cikin kwalban gilashin mara launi, an rufe hatimin hermetically tare da hula hade da aluminium da filastik tare da diski na roba ko maɗaurin tare da matattaka na roba tare da ƙugiya mai gudana hade da aluminium da filastik tare da daskararren filastik mai hawaye. Ana amfani da tambarin mai amfani da kansa ga kowane kwalba kuma a sanya shi a cikin fakitin kwali.

Mai masana'anta

GEROPHARM-Bio OJSC, Russia. 142279, Yankin Moscow, gundumar Serpukhov, r.p. Obolensk, gini 82, shafi 4.

Adreshin wuraren samarwa:

1. 142279, Yankin Moscow, gundumar Serpukhov, r.p. Obolensk, gini 82, shafi 4.

2.1422279, Yankin Moscow, Yankin Serpukhov, pos. Obolensk, gini 83, lit. AAN.

Da'awar karbar kungiyar: GEROPHARM LLC. 191144, Federationungiyar Rasha, St. Petersburg, Degtyarny ta., 11, lit. B.

Waya: (812) 703-79-75 (Multi-channel), fax: (812) 703-79-76.

Tẹli hotline: 8-800-333-4376 (kira tsakanin Rasha ba shi kyauta).

Aika bayani game da halayen da ba'a so ba zuwa adireshin imel [email protected] ko ta lambobin GEROFARM LLC da aka nuna a sama.

Abun ciki da nau'i na saki

Magungunan yana nufin magungunan da aka sayar da takardar sayan magani, tunda amfani da shi ba tare da kulawa ba zai iya cutar da jiki.

Maganin allura ne, babban abun ciki shine insulin ɗan adam, wanda aka kera shi ta amfani da fasahar DNA.

Karin kayan aikin maganin sune:

Ana yin sakin Rinsulin a cikin Rasha. Iya warware matsalar a bayyane yake kuma bashi da launi. An sanya shi a cikin kwalabe na gilashin 10 ml.

Halayen magunguna

Ana amfani da maganin ta hanyar tasirin hypoglycemic. Ana samar da raguwar glucose na jini ta hanyar tasirin manyan abubuwan. Insulin, yana shiga jikin mai haƙuri, yana kunna tsarin karɓar glucose da rarrabuwa a cikin sel. Rinsulin kuma yana rage yawan samar da sukari ta hanta.

Wannan kayan aiki yana da ɗan gajeren lokacin aiki. Zai fara shafar jikin rabin sa'a bayan allura. Yana yin aiki sosai a tsakanin sa'o'i 1-3 bayan amfani. Tasirinsa ya ƙare bayan sa'o'i 8.

Tasiri da tsawon lokacin bayyanar Rinsulin ya dogara da sashi da hanyar gudanarwa. Cire wannan kayan daga jiki shine gudana daga kodan.

Umarnin don amfani

An ba da shawarar yin amfani da magani don nau'in 1 da nau'in ciwon sukari na 2 idan ba zai yiwu a daidaita matakin sukari tare da magunguna don maganin baka ba. Rinsulin allura ce wacce za'a iya yi ta cikin ciki, ya yanke jiki ya shiga ciki. Mafi kyawun hanyar aikace-aikacen aikace-aikacen an yanke hukunci daban-daban.

An lissafta sashi na miyagun ƙwayoyi dangane da halaye na hoton asibiti. Mafi sau da yawa, 0.5-1 IU / kg na nauyin haƙuri ya kamata a gudanar dashi kowace rana.

An ba da izinin amfani da maganin a hade tare da sauran magungunan hypoglycemic, idan ya cancanta.

A mafi yawancin halayen, ana gudanar da rinsulin a ƙarƙashin ƙasa. Ya kamata a ba da allura ga cinya, kafada, ko bangon ciki. Yana da mahimmanci a madadin wuraren allura, in ba haka ba lipodystrophy na iya haɓaka.

Ana aiwatar da aikin na intramuscular ne kawai akan shawarar likita. A cikin ciki, wannan ne kawai daga mai ba da lafiya zai iya sarrafa shi. Ana amfani da wannan a cikin yanayin rikitarwa.

Darasi na bidiyo akan gabatarwar insulin ta amfani da alkairin sirinji:

M halayen

Shan kowane magani na iya haifar da mummunan sakamako. Don sanin menene matsaloli Rinsulin zai iya haifar, kuna buƙatar nazarin umarnin da sake dubawa a kan tattaunawar daga marasa lafiya.

Mafi yawan lokuta tare da amfani dashi, abubuwanda suka faru suna faruwa:

• halin hypoglycemic (yana haɗuwa tare da alamomi masu raunin da yawa, waɗanda suka haɗa da rashin ƙarfi, rauni, tashin zuciya, tachycardia, rudani, da sauransu),
• alerji (fatar fata, firgigin tashin hankali, ta Quincke's edema),
• karancin gani
• jan fata
• itching

Yawancin lokaci, sakamako masu illa suna faruwa lokacin amfani da miyagun ƙwayoyi duk da rashin haƙuri ga abun da ke ciki. Don kawar da mummunan abu, kuna buƙatar tuntuɓi ƙwararre. Wasu sakamako masu illa suna ɓacewa bayan ka dakatar da shansa, wasu kuma suna buƙatar maganin rashin lafiya.

Wasu lokuta bayyanar cututtukan cututtukan cututtukan cuta suna haifar da mummunar lalacewa a cikin lafiyar mai haƙuri, sannan yana buƙatar mummunan magani a asibiti.

Hulɗa da ƙwayoyi

Wani lokaci ana amfani da Rinsulin a cikin hadaddun farji, amma ya kamata a tsara shi da kyau. Akwai rukuni na kwayoyi saboda abin da hankalin jikinsa ga insulin ya inganta ko ya raunana. A cikin waɗannan halayen, wajibi ne don daidaita sashi na magungunan.

Ya kamata a rage wani yanki na Rinsulin yayin amfani dashi tare da hanyoyi masu zuwa:

• cututtukan hypoglycemic,
• salicylates,
• beta hanawa,
• MAO da ACE inhibitors,
• karafarini
• jami'in antifungal.

Tasirin Rinsulin yana raguwa idan aka yi amfani dashi tare da irin waɗannan ƙwayoyi kamar:

• kamuwa da cuta
• maganin alada
• magungunan hormonal.

Idan akwai buƙatar yin amfani da maganin Rinsulin lokaci guda kuma waɗannan kwayoyi, ya kamata ku ƙara yawan kashi.

Kada ku gyara jadawalin magani ba da izini ba. Idan ya yi yawa a jikin insulin ya shiga jiki, yawan zubar jini zai iya faruwa, babban abin da yake magana wanda yake shine hypoglycemia. Idan kayi amfani da kadan kadan na magani, magani zai zama mai tasiri.

Umarni na musamman

Ana yin matakan musamman yayin shan magunguna ga yara, mata masu juna biyu da tsofaffi.

Jiyya tare da Rinsulin yana haifar da bin ka'idodi masu zuwa:

1. Mata masu juna biyu. Babu buƙatar daidaita sashi na ƙwayoyi, tun da sashin aikinsa mai aiki ba ya shafar lokacin daukar ciki. Amma a lokaci guda, Wajibi ne a kula da matakin sukarin jini na mace, tunda lokacin ɗaukar yaro wannan manuniya na iya canzawa.
2. Iyayen mata masu shayarwa. Insulin baya wuce zuwa cikin nono kuma, saboda haka, baya tasiri akan jariri. Sabili da haka, baku buƙatar canza sashi ba. Amma ya kamata mace ta sa ido a kan abincinta, bin shawarwarin.
3. Tsofaffi mutane. Saboda canje-canje masu dangantaka da shekaru, jikinsu na iya zama mai saurin kamuwa da cutarwar. Wannan yana buƙatar cikakken binciken mai haƙuri da ƙididdigar yawan magunguna kafin a rubuta masa Rinsulin.
4. Yara. An kuma ba su izinin magani tare da wannan magani, amma a ƙarƙashin kulawar kwararrun. An wajabta maganin gwargwado.

Hakanan ana ba da umarni na musamman ga marasa lafiya waɗanda ke fama da cututtukan hanta da koda. Magungunan suna shafar hanta, kuma kodan suna da hannu wajen cire maganin daga jikin. Idan akwai matsaloli tare da waɗannan gabobin, to yakamata a rage kashi na Rinsulin don kada ya tsokani ƙwaƙwalwar ƙwayar cuta.

Idan kun yi haƙuri da wannan wakili a cikin haƙuri, dole ne ku maye gurbin shi da wani. Likita zai taimaka muku.

Mafi yawan lokuta, ana wajabta sauyawa:

1. Aiki. Magungunan yana dogara da insulin na mutum kuma yana kama da dakatarwa. Inje tare da wannan magani yana taimakawa wajen daidaita matakan glucose na jini. An haramta amfani da shi tare da hypoglycemia da rashin haƙuri ga abubuwan haɗin.
2. Rosinsulin. Ana sayar da wannan kayan aiki azaman maganin allura. An sanya shi cikin katako 3 ml. Babban abincinta shine insulin mutum.
3. Insuran. Magungunan yana dakatarwa ne wanda ake amfani dashi don amfani da subcutaneous. Ya bambanta a matsakaiciyar lokacin aiki. Insuran ne suka kirkireshi bisa insulin marassa lafiyar.

Ana amfani da waɗannan magungunan ta hanyar tasiri iri ɗaya, amma suna da wasu bambance-bambance waɗanda ya kamata a bincika. Hakanan kuna buƙatar sanin yadda za ku canza daidai daga wannan magani zuwa wani.

Rinsulin NPH

Wannan magani yana kama sosai da Rinsulin R. Ya ƙunshi insulin isophan. Magungunan yana da tsakaitaccen lokacin aiki kuma yana dakatarwa don yin allura.

Ana amfani dashi kawai a ƙarƙashin ƙasa, wanda ke taimakawa wajen yin sirinji na sikirin don Rinsulin NPH.

Wajibi ne a gabatar da miyagun ƙwayoyi a bangon ciki, cinya ko kafada. Domin abubuwan magunguna su sha da sauri, dole ne a yi allurar a sassa daban daban na jikin a cikin yankin da aka ayyana.

Wadannan abubuwan taimako na gaba shima bangare ne na Rinsulin NPH:

• phenol
• glycerin
• furotin sulfate,
• sodium hydrogen phosphate,
• metacresol
• ruwa.

An fito da wannan magani a cikin gilashin gilashin 10 ml. Dakatarwar fararen fat ce;

Wannan magani yana aiki kusan iri ɗaya ga Rinsulin R. Yana haɓaka yawan haɓakar glucose ta sel kuma yana rage jinkirin samar da shi ta hanta. Bambanci ya ta'allaka ne a cikin tsawon lokacin tasiri - yana iya kaiwa awanni 24.

Farashin Rinsulin NPH ya sauka sau 1100 rubles.

Kuna iya gano yadda tasirin maganin yake ta hanyar yin nazarin sake duba marasa haƙuri na Rinsulin P da NPH. Suna da bambanci sosai. Yawancin marasa lafiya suna ba da gaskiya ga waɗannan kwayoyi, amma akwai waɗanda waɗanda irin wannan magani bai dace ba. Rashin damuwa yana haifar da sakamako masu illa waɗanda zasu iya tsokani ƙwayoyi masu dauke da kwayar insulin.

Mafi sau da yawa, matsaloli sun faru a cikin masu ciwon sukari waɗanda ba sa bin umarnin ko a cikin waɗanda jikinsu ke kula da abubuwan da aka gyara. Wannan yana nufin cewa tasiri na miyagun ƙwayoyi ya dogara da yanayi da yawa.

Rinsulin R - kwatancen da siffofin sakin

Da ke ƙasa akwai wasu bayanai game da maganin da zai ba da hoto gaba ɗaya na insulin.

Rinsulin P yana haɗuwa da sauri cikin jini daga ƙwayar subcutaneous, tasirin hypoglycemic yana farawa bayan rabin sa'a. Kwayar halittar ta danganta ga masu karɓar sel, waɗanda ke ba da izinin jigilar glucose daga tasoshin jini zuwa kyallen. Rarfin Rinsulin don kunna glycogen samuwar da rage ƙimar glucose a cikin hanta kuma yana shafar raguwar glycemia.

Tasirin miyagun ƙwayoyi ya dogara da ƙimar sha, kuma cewa, bi da bi, akan kauri da wadatar jini na kashin da ke cikin ƙananan allurar. A matsakaici, magunguna na Rinsulin P sun yi kama da sauran gajerun insulins:

• lokacin farawa shine minti 30
• ganiya - kimanin awa 2
• babban aikin shine awa 5,
• jimlar lokacin aiki - har zuwa 8 hours.

Zaka iya hanzarta aikin insulin ta hanyar allura dashi cikin ciki ko babba, kuma ka rage shi ta hanyar saka shi a gaban cinya.

Don ramawa game da ciwon sukari mellitus akan Rinsulin, mai haƙuri dole ne ya bi abinci sau 6 a rana, tsaka-tsakin da ke tsakanin manyan abinci 3 ya kamata ya zama 5 awanni, a tsakanin su 10-20 g na jinkirin da ke motsa jiki ya zama wajibi.

Rinsulin P ya ƙunshi kayan aiki guda ɗaya kaɗai - insulin ɗan adam. An yi shi ne ta hanyar maimaitawa, wato, ta amfani da ƙwayoyin cuta na halittar jini. Yawancin lokaci ana amfani da E. coli ko yisti don waɗannan dalilai. A cikin tsari da tsari, wannan insulin din bashi da banbanci daga kwayar halittar da sinadarin dake motsa jini.

Akwai ƙananan abubuwan taimako a Rinsulin P fiye da yadda ake shigo da analogues. Bugu da ƙari ga insulin, ya ƙunshi ruwa kawai, metacresol mai kiyayewa da glycerol mai ƙarfi. A gefe guda, saboda wannan, yiwuwar rashin lafiyan halayen a wurin allurar yana da ƙasa. A gefe guda, sha cikin jini da ragewar sukari na Rinsulin na iya bambanta dan kadan. Saboda haka, sauya sheka zuwa wani magani tare da kayan aiki iri ɗaya na iya ɗaukar kwanaki da yawa, lokacin biyan diyyar ciwon sukari mellitus yayi rauni.

Sakin Fom

Rinsulin P shine mafita mara launi, cikakkiyar bayani, a cikin milliliter na 100 raka'oin.

Siffofin Saki:

1. Vials tare da maganin 10 ml, magani daga gare su dole ne a allura tare da sirinji na insulin.
2. 3 mlm katiri. Ana iya sanya su a cikin kowane alkawuran sirinji da aka tsara don daidaitaccen katun: HumaPen, BiomaticPen, Autopen Classic. Don samun ikon shigar da ainihin sashin insulin, zaɓi ya kamata a bai wa allurar sirinji tare da ƙara yawan adadin kashi. Misali, HumaPen Luxura yana ba ku damar gwada raka'a 0.5.
3. Abubuwan da za'a iya sakin alkalami Rinastra 3 ml. Sauya katun a cikinsu ba zai yuwu ba, mataki na 1.

Matsaloli marasa yiwuwa

Mitar sakamako na sakamako na Rinsulin yana da ƙasa, mafi yawan marasa lafiya kawai suna fuskantar matsalar rashin ƙarfi a cikin jini.

Jerin yiwuwar tasirin da ba'a so ba bisa ga umarnin:

1. Hypoglycemia yana yiwuwa idan aka lasafta yawan magungunan ba daidai ba kuma ya wuce buƙatun ilimin halayyar da ake kira hormone. Rashin bin umarni don amfani kuma na iya haifar da faɗuwar sukari: dabarar allurar da ba ta dace ba (insulin ya shiga cikin ƙwayar tsoka), dumama wurin allurar (zazzabi mai iska, damfara, gogayya), ɓarke ​​sirinji mai kuskure, aikin motsa jiki mara ƙima. Dole ne a kawar da hypoglycemia lokacin da alamun farko suka bayyana: zazzaɓi, rawar jiki, yunwar, ciwon kai. Yawancin lokaci, 10-15 g na carbohydrates mai sauri sun isa ga wannan: sukari, syrup, Allunan glucose. Mai tsananin hypoglycemia na iya haifar da lalacewa ta hanyar tsarin juyayi, yana haifar da coma.
2. Na biyu mafi yawan sakamako masu illa shine rashin lafiyan halayen. Mafi sau da yawa, ana bayyana su a cikin rauni ko ja a wurin allura kuma sun ɓace makonni biyu bayan alƙawarin maganin insulin. Idan itching ta kasance, za a iya shan maganin rigakafi. Idan rashin lafiyan ya juya ya zama babban tsari, cutar urticaria ko ta Quincke ta faru, dole ne a maye gurbin Rinsulin R.
3. Idan mai ciwon sukari ya kamu da cutar rashin jini a jiki na dogon lokaci, ana kirga kashi na farko na insulin ta yadda sukari jini ya ragu sosai, sama da wata daya. Tare da raguwa mai yawa a cikin glucose zuwa al'ada, lalacewa ta ɗan lokaci a cikin ƙoshin lafiya mai yiwuwa ne: wahayi mai gani, kumburi, jin zafi a cikin ƙwallon ƙafa - yadda ake lissafin yawan insulin.

Abubuwa da yawa suna yin tasiri akan aikin insulin, sabili da haka marasa lafiya masu ciwon sukari a kan ilimin insulin ya kamata su haɗa kai tare da likita duk magunguna, magungunan jama'a da bioadditives waɗanda suke shirin amfani da su.

Umarni yana ba da shawara don kulawa da kulawa ta musamman ga rukunoni masu zuwa na ƙwayoyi:

• magungunan hormonal: hanawa, hormones thyroid, glucocorticosteroids,
• magunguna don hauhawar jini: cututtukan tarin kwayoyin thiazide, duk magunguna suna ƙarewa – –Pril da –sartan, lazartan,
• Vitamin B3
• shirye-shiryen lithium
• karafarini
• kowane jami'in hypoglycemic
• Acetylsalicylic acid
• wasu maganin cututtukan fata.

Sakamakon ciwon sukari mellitus yana ƙaruwa kuma duk kwayoyi da abubuwan sha da ke ɗauke da giya na iya haifar da mummunan cutar hypoglycemia - duba abin da ke lalata cututtukan ƙwaƙwalwar ƙwayar cuta. Magungunan Beta-blocker da ake amfani da su a cikin cututtukan zuciya suna kwantar da alamun cututtukan jini da hana shi ganowa kan lokaci.

Siffofin aikace-aikace

Bayan aikin, an lalata insulin a cikin hanta da kodan. Idan mai ciwon sukari yana da cututtuka na ɗayan waɗannan gabobin, sashi na Rinsulin na iya buƙatar gyara. Ana buƙatar karuwar insulin a cikin lokutan canje-canje na hormonal, tare da cututtuka masu kamuwa da cuta, zazzabi, rauni, damuwa, rashin ƙarfi. Yawan maganin yana iya zama ba daidai ba idan mai haƙuri da ciwon sukari yana da amai, gudawa, da kumburi a cikin narkewa.

Likita na Kimiyyar Kimiyya, Shugaban Cibiyar Nazarin Diabetology - Tatyana Yakovleva

Na yi shekaru da yawa ina nazarin ciwon sukari. Yana da ban tsoro yayin da mutane da yawa suka mutu, har ma da yawa suna zama masu rauni saboda cutar sankara.

Na yi hanzarin ba da labari mai daɗi - Cibiyar Binciken Endocrinological na Kwalejin Kimiyya ta Rasha ta sami nasarar inganta maganin da ke warkar da ciwon sukari gaba daya. A yanzu, ingancin wannan magani yana gab da kashi 98%.

Wani albishir: Ma'aikatar Lafiya ta tabbatar da ɗaukar wani shiri na musamman wanda zai biya diyyar magunguna mai yawa. A Rasha, masu ciwon sukari har sai 18 ga Mayu (m) samun shi - Don kawai 147 rubles!

Shahararrun analogues na Rinsulin R sune Danish Actrapid da Tsarin Humulin na Amurka. Bayanan bincike sun nuna cewa ingancin alamun Rinsulin suna a matakin ka'idodin Turai.

Nazarin masu ciwon sukari ba su da kyakkyawan fata. Da yawa, lokacin sauya sheka daga magunguna da aka shigo da su zuwa na gida, lura da bukatar canji a sashi, tsalle sukari, da kuma kyakkyawan yanayin aiki. Akwai ƙarin ingantattun sake dubawa game da rinsulin a tsakanin marasa lafiya waɗanda ke amfani da insulin a karon farko. Suna sarrafa don samun sakamako mai kyau ga masu ciwon sukari kuma suna guje wa mummunar cutar hypoglycemia.

Idan m alerji na faruwa, dole ne a yi watsi da Rinsulin. Yawancin lokaci, sauran insulins suna haifar da irin wannan amsawa, don haka suna amfani da hanyar ultrashort - Humalog ko NovoRapid.

Farashin Rinsulin P - daga 400 rubles. kowace kwalba har zuwa 1150 don alkalami 5.

Bambanci tsakanin Rinsulin P da NPH

Rinsulin NPH magani ne na yau da kullun daga masana'anta guda. Dangane da umarnin, ana amfani dashi don daidaita sukari mai azumi. Rinsulin NPH yana da tsari guda ɗaya na aiki, tsari saki, alamu masu kama da juna, contraindications da sakamako masu illa kamar Rinsulin R. A matsayinka na doka, tare da maganin insulin duka nau'ikan insulin an haɗa su - gajere da matsakaici. Idan sirrin jikin ku na wani bangare an kiyaye shi (nau'in 2 da cutar sikari), zaka iya amfani da magani daya kawai.

Fasali na Rinsulin NPH:

Farashin kwalban Rinsulin NPH

400 rub., Kayan katako guda biyar

1000 rub., Filin sirinji biyar

Tabbatar koya! Shin kuna tsammanin kulawa da kwayoyin hana daukar ciki da insulin shine hanya daya tilo da za'a kula da sukari? Ba gaskiya bane! Kuna iya tabbatar da wannan da kanku ta hanyar fara amfani da shi. kara karantawa >>