Siffar magungunan statin don rage cholesterol

An gano sabbin halittun ƙarni na ƙarshe a matsayin magunguna mafi inganci kuma amintattu a cikin yaƙi da rikice-rikice na atherosclerosis. Magunguna suna taimakawa rage yawan ƙwayoyin cuta, da sauran samfurori na metabolism mai. Stataukar mutum-mutumi yana jinkirta haɗarin haɓaka rikitattun cututtukan zuciya - bugun zuciya, bugun jini.

Cutar cututtukan zuciya na daukar matsayi na farko a cikin sanadin mace-mace. A cewar Ma’aikatar Lafiya, a shekarar 2017, kashi 47.8% na ‘yan kasar Rasha ne suka mutu sakamakon kamuwa da cututtukan zuciya. WHO ta yi hasashen cewa wannan adadi zai karu saboda tsufa mai hankali, da kuma canje-canjen rayuwa.

Statins: menene, wanene aka sanya

Statins magunguna ne da ke toshe sinadarin cholesterol a cikin hanta, da maye gurbin sinadarin HMG-CoA reductase. Saboda haka, sunan su na hukuma shine HMG-CoA reductase inhibitors. Bugu da kari, statins suna rage taro na “cutarwa” na rashin wadataccen kayan aiki na lipoproteins (LDL), kara matakin “kyau” mai girma mai yawa na garkuwar jiki (HDL).

Normalizing taro na cholesterol, LDL, HDL yana taimakawa hana ci gaba da atherosclerosis, rikitarwarsa: bugun zuciya, bugun jini, necrosis na ƙananan ƙarshen. Tare da thrombosis da hauhawar jini, an gano wannan cutar a matsayin mafi muni ga dukkanin cututtukan zuciya.

A cikin Turai, Amurka, al'adar adana abubuwan tarihi suna da yawa. 95% na Amurkawa, 55% na marasa lafiya na Turai waɗanda ke wajabta magunguna, suna ɗaukar su. A cikin Rasha, wannan adadi 12% ne kawai. Wani binciken na kasa da kasa, VALIANT, ya nuna cewa likitocinmu suna tsara mutum-mutumi sau 100 kasa da abokan aikin sa na kasashen waje.

Adana gumaka yana ba ka damar:

  • rage hadarin bugun zuciya, bugun jini,
  • rage yawan marasa lafiya da ciwon zuciya wanda ke buƙatar asibiti,
  • rage yawan ayyukan da ake yi don maido da kwararar jini,
  • hana kai harin angina.

Duk da ƙarfin maganin warkewa, ana ɗaukar allunan statin don bayyanannun alamun, kuma ba don kowane karuwa na cholesterol ba. Ba su da lahani, suna da mummunan illa. Ana bada shawarar Statins ga mutane:

  • waɗanda suka tsira daga ciwon zuciya, bugun jini, microstroke,
  • shirye-shiryen tiyata a kan jijiyoyin jini,
  • tare da matakan LDL fiye da 190 mg / dL (4.9 mmol / L),
  • fama da ciwon sukari da kuma samun LDL na 70-189 mg / dl (1.8-4.9 mmol / l),
  • Yara sama da shekaru 10 wadanda ke cikin hadarin kamuwa da cutar bugun zuciya.

Atorvastatin

Mafi kyawun siyayya a duniya. A cikin iko, yana gaban magunguna na baya (simvastatin, pravastatin, lovastatin). Amfani da shi a cikin yawancin marasa lafiya yana ba ku damar cimma daidaitaccen raguwa a cikin ƙwayar cholesterol zuwa matakin da aka ba da shawarar. A lokaci guda, farashin Allunan sun fi yawa idan aka kwatanta da rosuvastatin, kuma haƙuri a cikin marasa lafiya da yawa sun fi kyau.

Rosuvastatin

Ana amfani da wannan magani mafi ƙarfi daga cikin abubuwan da ke kasancewa. An wajabta Rosuvastatin a cikin mafi yawan lokuta masu tasowa, lokacin da alƙawarin wasu kwayoyi ba su ba da damar cimma daidaitaccen raguwar cholesterol, LDL. A yau babu yarjejeniya game da cancantar yin amfani da shi a cikin marasa lafiya tare da m hypercholesterolemia, ƙananan haɗarin haɓakar rikice-rikice na zuciya. An fitar da magani kwanan nan, an yi nazarin aikinsa mafi muni da atorvastatin. Saboda haka, wasu tambayoyi, musamman idan suna da alaƙa da sakamakon na dogon lokaci, babu tabbataccen amsa.

Pitavastatin

Fairlywararrun ƙwayoyi na ƙarni na 4 mai sauƙi, wanda kamfanin Spanish Recordati Masana'antar Magunguna na Magunguna sun samar da shi a ƙarƙashin sunan cinikin Livazo. Idan aka kwatanta da sanannen rosuvastatin, an yi nazarin da yafi muni. Sabili da haka, likitoci suna tsara pitavastatin don rage cholesterol akai-akai. Ana ba da ita ga mafi yawan lokuta ga marasa lafiya a matsayin madadin rosuvastatin idan akwai rashin haƙuri. Kudin Livazo shine 540-1205 rubles.

Statins na ƙarni na ƙarshe: an nuna sunayen kwayoyi na 3, 4 tsararraki a cikin tebur.

Sunan maganiZaɓuɓɓukan sashi, mgKudin, rub.
Abincin aiki mai aiki - atorvastatin
Atorvastatin10, 20, 40, 8070-633
Atorvastatin Alkaloid86-215
Atorvastatin MS10, 20, 4078-153
Atorvastatin SZ10, 20, 40, 8054-497
Atorvastatin OBL10, 20, 40, 80171-350
Atorvastatin LEXVM10, 2085-210
Atorvastatin Teva10, 20, 40, 8074-690
Atoris10, 20, 30, 40, 60, 80175-1248
Vazator10, 20291-388
Liprimar10, 20, 40, 80590-1580
Novostat10, 20, 40, 80100-497
Thorvacard10, 20, 40238-1773
Torvas10, 20, 40, 80203-440
Tulip10, 20, 40111-1180
Abincin aiki - rosuvastatin
Akorta10, 20350-1279
Kanta5, 10, 20, 401458-9398
Lipoprime5, 10, 20355-460
Mertenyl5, 10, 20, 40338-2200
Reddistatin5, 10, 20, 40327-1026
Ro statin5, 10, 20, 40449-699
Rosart5, 10, 20, 40202-2839
Harshen Ros10, 20, 40225-1850
Rosuvastatin-SZ5, 10, 20, 40158-1260
Rosuvastatin Vial10, 20331-520
Roxer5, 10, 15, 20, 30 ,40353-2098
Rosucard10, 20, 40374-3800
Rosulip5, 10, 20, 40240-1736
Suvardio5, 10, 20, 40220-912
Tevastor5, 10, 20, 40303-2393

Wanne ne daga cikin sababbin insan adam na da sideancin sakamako masu illa? Mafi amintattu sune asalin siffofin Liprimar (atorvastatin), Crestor (rosuvastatin). Farashin su ya sha bamban da analogues, amma yana da cikakken barata. Idan kasafin kudin mai haƙuri ya sauƙaƙa, an tsara shi a madadin masu kyau tare da kyakkyawan suna: Tulip, Torvakard, Atoris, Rosucard, Lipoprime. Likita na iya tsara wasu magunguna dangane da irin kwarewar da suka sha tare da maganin. Kada ku sayi takwarorinsu masu arha. Inganci, amincin suna cikin shakka.

Bambanci tsakanin kwayoyi na sabon da tsoho

Akwai tsoffin statan adam 4:

  • na farkon shine simvastatin, lovastatin, pravastatin,
  • na biyu shine fluvastatin,
  • na uku shine atorvastatin,
  • na huɗu shine rosuvastatin, pitavastatin.

Rosuvastatin sau 1.5-2 mafi kyau yana rage LDL fiye da atorvastatin, sau 4 fiye da simvastatin, sau 8 fiye da pravastatin ko lovastatin. Ana ɗaukar taro na "cutarwa" na lipoproteins shine babban mai nuna alama wanda ke shafar rage girman haɗarin cututtukan zuciya. Ana amfani dashi don hango ko hasashen maganin zai iya tasiri.

Hanyar metabolins na mutanen karshe yana kama da kwayoyi na 1-2 zamanin, amma tare da sakamako masu illa. Wannan yana ba ku damar tsara su lokaci guda tare da wasu kwayoyi waɗanda ba su dace da simva-, kamun kifi, pravastatin ba. Wannan fa'idar yana faɗaɗa da'irar masu haƙuri.

Babban bambanci tsakanin allon tsoffin tsararraki shine ikon rage matakin C-reactive protein (CRP factor). Sabbin karatun suna tilasta likitoci su gane cewa wannan sinadaran na iya taka rawar da ya taka a ci gaban atherosclerosis fiye da cholesterol. Normalization na matakin sa ba ka damar da kyau hana ci gaban da cutar, kazalika da hana ci gaban da matsaloli na barazanar rayuwa. Wannan fili yana bayyane ne kawai a cikin rosuvastatin, har ma da analogues.

Sauran karfin jituwa

Statan mutum na uku da na huɗu sun fi dacewa da wasu kwayoyi. Atorvastatin ba za a iya tsara shi lokaci guda tare da:

  • gemfibrozil,
  • hade da tipranavir tare da ritonavir,
  • tsinkaya
  • cyclosporine.

Gyara yawan allunan ya zama dole yayin da ake shan magunguna masu zuwa:

  • boceprivir,
  • verapamil
  • digoxin
  • diltiazem
  • itraconazole,
  • Sankasari,
  • colchicine
  • lopinavir tare da ritonavir,
  • nelfinavir
  • niacin
  • omeprazole
  • ezetimibe.

Allunan kwayoyi na Rosuvastatin sun banbanta da sauran mutum-mutumi a cikin mu'amalarsu da cytochrome P450 enzymes Zai iya, amma wanda ba a so, a matsayin magani a matsayin ƙari ga hanya tare da magunguna tare da sauran masu hana haɓaka HMG-CoA ba su dace ba. Ba a tsara shirye-shiryen Rosuvastatin ga marasa lafiya waɗanda ke ɗaukar fibrates, cyclosporine.

Fa'idodi da cutarwa na statins

Sayar da magunguna don sabon ƙarni na ƙwayar cholesterol ya barata idan akwai hujja. Dangane da bincike, ana iya rage amfani da rosuvastatin ta:

  • Kashi 20% na mace-mace,
  • 44% mace-mace daga rikice-rikice na atherosclerosis,
  • 50% damar samun bugun jini, bugun zuciya.

Wasu gumakan za su iya yin fahariya da ƙarin daidaitattun abubuwa, amma har yanzu suna da kyau. Dalilinsu zai iya ragewa ta:

  • Kashi 20,2% na mace-mace,
  • 25-37% abin da ya faru na ta hanyar myocardial infarction,
  • 28-31% damar bugun jini.

Abin takaici, gumaka ba su da cikakken kariya. Kwayoyin kwayoyi suna da mummunar sakamako masu yawa, ƙwayoyin contraindications da yawa. Ba a rubuta su ga mutanen da:

  • da cutar hanta
  • orsaramin (banda - ƙwayar cuta mai saurin kamuwa da ita, wadda ke haɗuwa da babban cholesterol),
  • mata masu juna biyu, da waccan matan da suke shirin yin ciki,
  • lactating.

Yawancin sakamako masu illa na yau da kullun ba su da haɗari. Kimanin 12% na marasa lafiya suna fama da ciwon makogwaro, 6.6% na ciwon kai, 5.3% na alamu kamar sanyi, 5.1% na ciwon tsoka. Yawancin marasa lafiya suna ba da rahoton haɓakawa ga lafiyar gaba ɗaya yayin ɗaukar maganin bayan aan kwanaki ko makonni. Amma wasu mutane suna ci gaba da fuskantar rashin jin daɗi a duk lokacin karatun.

Hanya mafi tsattsauran ra'ayi don kawar da tasirin sakamako ita ce barin siffofin mutum. Kafin yanke shawarar daina magani, likitocin sun bada shawarar yin la’akari da ribobi da kuma fursunoni. Bayan haka, mutum-mutumi mutum yana karawa mutum rai, kuma yana da kyau a dage da karamin lalacewa cikin walwala. Haka kuma, akwai wasu hanyoyin da zasu inganta yanayin gaba daya:

  • yarda da wani ɗan gajeren hutu don shan maganin. Kalli canje-canje. Wani lokacin zafin ƙwayar tsoka, rauni na gaba ɗaya shine sakamakon tsufa ko wasu cututtuka, kuma ba sakamakon sakamako na kwayoyi. Harshen su zai magance rashin jin daɗi,
  • Tambayi likitanka don maye gurbin magani ko rage sashi. Statins babban rukuni ne na kwayoyi, wanda ke bawa kowane mara lafiya damar zabar wani magani wanda yafi dacewa dashi,
  • tattauna hadewar gumaka da sauran magungunan rage karfin kwalagin cholesterol. Statins sune magunguna mafi inganci don daidaita matakan cholesterol. Amma wani lokacin, haɗuwarsu tare da wasu magunguna na iya rage kashi, kiyaye matakin LDL a matsayin mara ƙaranci.
  • motsa jiki a hankali. Aiki na jiki na iya cutar da tsokoki a matakin salula. A bango na ɗaukar Hhib-CoA reductase inhibitors, wannan ya cika tare da mummunan rauni na tsoka. Zai iya zama daidai a sake tsarin shirin darasi ta ɗan rage nauyin,
  • coauki coenzyme Wannan ƙarin abincin yana taimakawa hana wasu sakamako masu illa a cikin ɗan karamin rabo daga mutane.

An yi imanin cewa masu hana HMG-CoA reductase na iya tayar da cutar sankara. Wannan ra'ayin yanzunnan gaskiya ne. An gudanar da bincike mai zurfi na JUPITER, yayin da aka bincika yanayin lafiyar marasa lafiya 17 802 wadanda suka dauki rosuvastatin. Nau'in na 2 na ciwon sukari mellitus ya ɓullo a cikin marasa lafiya 270 waɗanda ke shan kwaya, akasin 216 na cututtukan cututtukan ƙwaƙwalwa tsakanin waɗanda suka ɗauki placebo. Likitocin sun yi bayanin dan kadan karuwar cutar mutane a rukunin binciken don ci gaban ciwon sukari.

Me yasa cholesterol yake tashi?

Cholesterol wani kwaroron halitta ne wanda yake a jikin mutum wanda yake aiki da shi. Abune mai mahimmanci wanda ya shafi lafiyar kiba.

Mayar da hankali na abu na iya wuce ka'idodin da aka kafa. Wannan ya cutar da lafiyar kuma yana haifar da cututtuka da yawa. Waɗannan sun haɗa da bugun zuciya da bugun jini, angina pectoris, atherosclerosis.

20% na cholesterol na waje yana fitowa ne daga abinci, sauran kashi 80% kuma jiki yake samarwa. Idan akwai batun cin hancin da kuma cire wani abu, abubuwansa zasu canza.

Abubuwan na ciki da na waje na iya haifar da haɓaka cholesterol:

  • cuta cuta na rayuwa
  • dabi'ar gado
  • yawan abinci mai yawa da abinci mai yawa,
  • amfani da wasu magunguna
  • hauhawar jini
  • na kullum damuwa
  • ciwon sukari mellitus
  • rashin motsa jiki
  • rashin daidaituwa na hormonal ko maimaitawa,
  • kiba da kiba
  • tsufa.

Alamu don nazarin dakin gwaje-gwaje sune:

  • gano cutar atherosclerosis da rigakafin ta idan tana cikin hatsari,
  • gaban sauran cututtukan zuciya,
  • ilimin cutar koda
  • cututtukan endocrine - cututtukan jini,
  • ciwon sukari
  • ilimin halittar hanta.

Idan an sami ɓarna, likita ya tsara hanyoyi da yawa don rage ƙwayar cholesterol. Ana iya tsara magungunan Statin dangane da hoton asibiti.

Menene statins?

Wannan rukuni ne na magungunan rage yawan lipid da aka tsara don rage mummunar cholesterol. Sun toshe ayyukan enzyme na hanta, wanda ke haɗu da samar da abu.

Ana la'akari da Statins masu inganci a cikin rigakafin cututtukan cututtukan zuciya na asali da maimaitawa. Kungiyar gungun kwayoyi suna daidaita yanayin tsarin jini kuma yana hana samuwar filaye.

Tare da magunguna na yau da kullun, marasa lafiya suna sarrafa ƙananan cholesterol zuwa 40%. A cewar kididdigar, suna rage mace-mace daga cututtukan zuciya da kusan sau 2.

Magungunan suna da tasirin cholesterol, rage sautin na lipoproteins ta hanta, daidaita halayen jini, rage danko, ƙara haɓaka tasoshin jini, shakata da fadada su, da hana ƙirƙirar filaye a jikin bango.

Har yaushe za a ɗauka? Magungunan suna aiki ne kawai yayin liyafar, bayan an dakatar dashi, alamu na iya komawa zuwa ga alkaluman da suka gabata. Ba a cire amfani da dindindin ba.

Alamu don amfani

Abubuwan da ke nuna alamun amfani da statins don rage cholesterol:

  • basantankara,
  • mai rauni atherosclerosis da haɗarin ci gabanta,
  • na farko rigakafin bugun jini, bugun zuciya,
  • kulawar jiki bayan bugun zuciya, bugun zuciya,
  • tsufa (dangane da bincike)
  • angina pectoris
  • Ciwon zuciya,
  • hadarin toshewar hanyoyin jini,
  • Abubuwan haɗin kai na dan adam (na dangi) hypercholesterolemia,
  • hanyoyin tiyata a zuciya da jijiyoyin jini.

Daga cikin abubuwan da ake amfani da su wajen amfani da siffofin:

  • koda dysfunction
  • rashin haƙuri da aka gyara
  • ciki
  • ciyar da nono
  • tashin hankali
  • shekaru zuwa shekaru 18.

Jerin magungunan statin

Magungunan Statin suna wakiltar ƙarni 4.

A cikin kowane ɗayansu akwai abubuwa masu aiki waɗanda ake rarrabe su da lokacin aiwatarwa:

  1. Zamanin farko - Lovastatin, Simvastatin, Pravastatin. Asalin na halitta ne. Ayyukan rage darajar cholesterol shine 25%. Ba su da fa'ida a cikin rage darajar kuma mafi kusantar su nuna sakamako masu illa. Tsararrakin suna wakiltar waɗannan magunguna masu zuwa: Vasilip - 150 r, Zokor - 37 r, Lovastatin - 195 r, Lipostat - 540 r.
  2. Tsarin na biyu shine fluvastatin. Asalin shi ne Semi-roba. Alamar raguwa na aiki - 30%. aiki mafi tsayi da kuma tasiri kan alamu fiye da magabata. Sunayen miyagun ƙwayoyi na 2: Leskol da Leskol Forte. Farashin su kusan 865 p.
  3. Zamani na uku shine Atorvastatin. Asalin abin roba ne. Ayyukan rage taro shine abu yakai 45%. Rage matakin LDL, TG, ƙara HDL. Rukunin magungunan sun hada da: Atokor - 130 rubles, Atorvasterol - 280 p, Atoris - 330 p, Limistin - 233 p, Liprimar - 927 p, Torvakard - 250 p, Tulip - 740 p, Atorvastatin - 127 p.
  4. Tsarin na huɗu shine Rosuvastatin, Pitavastatin. Asalin abin roba ne. Ayyukan rage darajar cholesterol kusan 55%.Zamani na gaba, mai kama da aiki zuwa na ukun. Nuna tasirin warkewa a ƙananan sashi. A hade tare da sauran magungunan zuciya. Amintaccen aminci da tasiri fiye da waɗanda suka gabata. Rukuni na 4 na rukuni na kwayoyi sun hada da: Rosulip - 280 r, Rovamed - 180 r. Tevastor - 770 p, Rosusta - 343 p, Rosart - 250 p, Mertenil - 250 p, Crestor - 425 p.

Tasiri a jiki

Magungunan Statin suna taimakawa marasa lafiya da cututtukan zuciya. Suna rage kumburi a cikin tasoshin, cholesterol, rage haɗarin cututtukan zuciya da bugun jini. Hakanan magunguna suna haifar da sakamako masu illa daga mai laushi zuwa mara nauyi.

Tunda aka ɗauki allunan na dogon lokaci, hanta tana cikin haɗari. A kan aiwatar da magani, sau da yawa a shekara, ana ba da ilimin halittar jini.

Side effects na kwayoyi sun hada da:

  • yanayin rashin lafiyan fata,
  • ciwon kai da danshi,
  • weaknessara rauni da gajiya,
  • rikicewar gastrointestinal
  • na gefe neuropathy,
  • hepatitis
  • rage libido, rashin ƙarfi,
  • ciwon ciki
  • na gefe harshe,
  • mai rauni, ƙwaƙwalwar ƙwaƙwalwar ajiya daban-daban,
  • thrombocytopenia
  • rauni na tsoka da jijiyar wuya
  • matsalolin hanta
  • ciwon kai
  • amnesia na yau da kullun na duniya - da wuya,
  • rhabdomyolysis ne mai wuya.

Wanne magani zaba?

Statins rukuni ne na ingantattun magunguna. Ba a yi nufin su ba da magani ba. Likitocin halartar ne ke yin su, suna yin la’akari da tsananin cutar da kuma sakamakon binciken. Yana yin la'akari da duk haɗarin da ke tattare da shekaru, cututtukan haɗin gwiwa, shan wasu magunguna.

A tsakanin watanni shida, ana gabatar da binciken ƙirar ƙwayoyin halitta kowane wata don saka idanu akan alamun ayyukan hanta. Ana yin ƙarin karatun sau 3-4 a shekara.

Yaya aka zaɓi maganin? Likita ya zabi maganin kuma ya tsara hanya. Bayan an kammala shi, ana sa ido kan masu nuna alama. Idan babu sakamako, tare da isasshen magani, bayyanar sakamako masu illa, an tsara wani magani. Bayan an dauko magunguna masu mahimmanci, an shirya makircin.

Sakamakon sakamako, hade tare da wasu magunguna, ana la'akari da tsawon lokacin gudanarwa. Ana gano gumakan mutanen ƙarshe da suka fi kyau. Suna nuna ingantaccen ma'aunin aminci da aiki.

Kusan babu wani tasiri akan metabolism na metabolism, tafi lafiya tare da sauran magungunan zuciya. Ta hanyar rage sashi (tare da tasirin sakamako), haɗarin ci gaban sakamako zai ragu.

Labarin bidiyo daga Dr. Malysheva game da statins:

Mai haƙuri ra'ayi

Nazarin haƙuri yana nuna kasancewar halaye masu kyau da marasa kyau a cikin lura da statins. Da yawa suna jayayya cewa a cikin yaƙar cholesterol mai yawa, kwayoyi suna nuna sakamakon da ake gani. An kuma lura da yawan sakamako masu illa.

Reviews of likitoci game da statins suna hade. Wasu suna da'awar amfaninsu da amfaninsu, waɗansu kuwa suna ɗaukar su mugaye ne.

Sun sanya ni Atoris don rage cholesterol. Bayan shan wannan magani, mai nuna alamar ya ragu daga 7.2 zuwa 4.3. Dukkanin abubuwa suna tafiya da kyau, sa'annan kumburi ya bayyana a hankali, tare da jin zafi a cikin gidajen abinci da tsokoki sun fara. Yin haƙuri ya zama ba za a iya jurewa ba. An dakatar da jiyya. Makonni biyu baya, komai ya tafi. Zan je wurin likita, bari ya ba da wasu magunguna.

Olga Petrovna, mai shekara 66, Khabarovsk

An yiwa mahaifina Crestor. Ya kasance na ƙarshen ƙarni na statins, mafi dacewa duka. Kafin wannan akwai Leskol, akwai wasu sakamako masu illa. Dad ya kwashe kusan shekara biyu yana shan Krestor. Yana nuna kyakkyawan sakamako, kuma bayanin martaba na lipid ya cika duk matakan. Lokaci-lokaci wasu lokutan sukan shiga wahala. Likitan da ke halartar ya ce sakamakon har ya fi yadda aka zata. Don adana kuɗi, ba za mu so canzawa zuwa rahusa analogues mai rahusa ba.

Oksana Petrova, dan shekara 37, St. Petersburg

Suruwar mahaifiyar ta kwashe shekaru 5 tana ɗaukar gumaka bayan wani mummunan rauni. Sau da yawa canza shirye-shiryen. Didayan bai rage cholesterol ba, ɗayan bai dace ba. Bayan zaɓin da hankali, mun tsaya a Akorta. Daga dukkan magunguna, ya zama ya fi dacewa da ƙarancin sakamako. Sanarwar uwa-uba kullun tana lura da yanayin hanta. Gwajin ba koyaushe bane al'ada. Amma a yanayin ta, babu wani zabi na musamman.

Alevtina Agafonova, ɗan shekara 42, Smolensk

Likita ya ba ni Rosuvastatin a gare ni - ya ce wannan ƙarni ne mafi kyau, tare da ƙarancin sakamako. Na karanta umarnin don amfani, har ma da ɗan tsoro. Akwai ƙarin contraindications da sakamako masu illa fiye da alamomi da fa'idodi. Ya zama cewa muna bi da ɗa, kuma mun datse ɗayan. Na fara shan magani, Ina sha har tsawon wata ɗaya, Ya zuwa yanzu ba tare da wuce haddi ba.

Valentin Semenovich, mai shekara 60, Ulyanovsk

Statins suna da mahimmanci a atherosclerosis, bugun zuciya, da bugun jini. Abin baƙin ciki, a wasu yanayi mutum ba zai iya yi ba tare da su ba. Magunguna ba za su iya magance matsalar hana rikice-rikice ba gaba daya. Amma wasu nasarorin da aka samu a aikacersu a bayyane yake.

Agapova L.L., likitan zuciya

Statins rukuni ne na magunguna waɗanda ke kan jerin magunguna masu mahimmanci a cikin yaƙi da cholesterolemia da sakamakonta. Tare da taimakonsu, yana yiwuwa a iya rage yawan mace-mace daga shanyewar jiki da cututtukan zuciya. Ana ganin ƙarni na huɗu mafi inganci kuma mai aminci.

Statins - menene

Statins rukuni ne na kwayoyi waɗanda aka tsara don rage cholesterol jini. Amma magungunan ba su shafe shi kai tsaye. Suna shafar hanta, suna hana ruɗar enzyme wanda ke haɗuwa da samin ƙwayoyin cholesterol.

A jikin mutum sune abubuwanda yake sanyawa - lipoproteins. Suna da girma da ƙarancin girma. Idan tafiyar matakai na rayuwa ba su da damuwa, to lipoproteins ba su haifar da haɗarin kiwon lafiya ba. Amma wuce haddi na cholesterol yana ba da gudummawa ga ƙirƙirar filaye, wanda ke haifar da ci gaba da manyan cututtuka.

Statins suna da niyyar rage yawan adadin masu ɗaukar cholesterol zuwa kyallen. A lokaci guda, yawan adadin masu karɓar lipoprotein mai yawa akan hepatocytes yana ƙaruwa. Wato, suna canja wurin cholesterol a cikin kishiyar sashi - daga magudanar jini zuwa hanta. Godiya ga waɗannan magungunan, ƙwayar cholesterol an daidaita shi. Amfani da su yana ba da gudummawa wajen kawo abubuwanda ke cikin al'ada.

Mahimmanci! Wani cholesterol ya dauki statins na? Suna da mahimmanci ga mutumin da ke da nuni sama da 5 mmol / l. Bayan infarction na zuciya na myocardial, a cikin cututtukan zuciya masu rauni, makasudin cholesterol yana raguwa.

Fasali na rarrabuwar gumakan

Akwai hanyoyi da yawa don rarrabe statins:

  1. Ga tsararraki: na farko, na biyu, na uku da na ƙarshe.
  2. Ta hanyar asali: roba, Semi-roba da na halitta.
  3. Dangane da taro na abubuwa masu aiki: babban kashi, matsakaici da ƙananan kashi.

Arshe na ƙarshen ya fi dacewa, tunda ana tsara statins a allurai dabam-dabam.

Statananan ƙwayoyin cholesterol

Don rage cholesterol na jini, an wajabta abinci na musamman. Ya zama dole, kamar yadda wasu abinci suke ɗauke da sifofin ɗabi'a.

Rage cholesterol ba tare da magani ba zai yiwu tare da amfani da:

  1. Samfura dauke da sinadarin ascorbic acid. Waɗannan sun haɗa da 'ya'yan itacen citrus, baƙar fata currants, buckthorn teku, kwatangwalo, fure mai zaki.
  2. Samfura tare da nicotinic acid. Waɗannan duk nau'ikan kwayoyi ne, nama mai ɗumi, jan kifi.
  3. Omega-3 mai kitse - jan kifi, kowane mai kayan lambu.
  4. Polyconazole. Ana samo shi a cikin tsarin sukari, kuma za'a iya siyar dashi a kantin magani.
  5. Pectin. An lura da mafi girman yawan hankali a cikin apples, karas, kabeji, wake, hatsi, bran.
  6. Resveratrol innabi ne.
  7. Turmeric

Tafarnuwa kuma yana taimakawa rage ƙwayar cholesterol.

Shin ina buƙatar shan ginin mutum yayin da nake bin abincin da aka kashe? Cutar da ta dace shine ɓangaren maganin. Sabili da haka, yawanci don daidaita yanayin, mai haƙuri yana canza abincin kuma yana shan magunguna na wannan rukuni.

Contraindications

Da farko dai, wannan rukuni na kwayoyi yana contraindicated a cikin mata yayin daukar ciki. Hakanan haramun ne a yi amfani da su a irin waɗannan halaye:

  • bayyanar rashin lafiyan mutum, rashin jituwa ga abubuwan magungunan,
  • mummunan cutar koda
  • dysfunction na tsarin endocrine,
  • pathology na musculoskeletal tsarin,
  • cututtukan hanta na kullum.

Idan kayi amfani da statins na dogon lokaci a cikin babban sashi, zasu iya haifar da irin wannan sakamako:

  • zafi a cikin gastrointestinal fili,
  • maƙarƙashiya
  • tashin zuciya da amai
  • ƙaramar platelet,
  • kumburi daga cikin manya da ƙananan hanji,
  • kiba, kiba,
  • jijiyar wuya
  • ciwon baya
  • hadin gwiwa cututtuka.

Hakanan, dacewa da kwayoyi tare da kulawa mai rikitarwa ya kamata a la'akari dashi. Yin amfani da kwayoyi ba a jituwa tare da statins na iya haifar da mummunan sakamako.

Ta tattarawa, yakamata a lura cewa statins suna da matukar hadari kuma ana amfani da magunguna idan aka yi amfani dasu daidai. Lokacin nazarin kimanta halaye na mutum, cututtukan haɗin gwiwa na haƙuri, likitan halartar zai zaɓi hanyar mafi inganci.

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