Analogues na allunan Rosucard
Analogues na miyagun ƙwayoyi rosucard, m don tasirin jiki, ana gabatar da shirye-shiryen dauke da ɗaya ko fiye da abubuwa masu aiki iri ɗaya. Lokacin zabar kalmomin kama da juna, yi la'akari da farashin su ba kawai, har ma da ƙasar da aka ƙera da martabar mai ƙira.
- Bayanin maganin
- Jerin analogues da farashin
- Nasiha
- Umarni don amfani
Bayanin maganin
Rosucard - Magungunan zubar jini daga rukunin gumakan. Zabi mai hana ingila na HMG-CoA reductase, mai samar da enzyme wanda ke canza HMG-CoA zuwa mevalonate, mai keratin cholesterol (Ch).
Theara yawan masu karɓar LDL a saman hepatocytes, wanda ke haifar da karuwar haɓakawa da catabolism na LDL, hanawar haɗakar VLDL, rage yawan haɗakar LDL da VLDL. Rage yawan taro na LDL-C, HDL cholesterol-non-lipoproteins (HDL-non-HDL), HDL-V, cikakken cholesterol, TG, TG-VLDL, apolipoprotein B (ApoV), rage yawan rabo daga LDL-C / LDL-C, jimlar HDL-C, Chs-not HDL-C / HDL-C, ApoB / apolipoprotein A-1 (ApoA-1), yana kara yawan kwarin gwiwar HDL-C da ApoA-1.
Sakamakon rage ƙwayar lipid shine gwargwadon kai tsaye zuwa yawan adadin da aka tsara. Tasirin warkewa yana bayyana a cikin mako 1 bayan farawar, bayan makonni 2 ya kai 90% na matsakaicin, ya kai matsakaicin har zuwa makonni 4 sannan kuma ya kasance koyaushe.
Tebur 1. Sakamakon-kashi dogaro a cikin marasa lafiya da keɓaɓɓen hypercholesterolemia (nau'in IIa da IIb gwargwadon rarrabuwa da Fredrickson) (matsakaiciyar sauyin da aka daidaita sau ɗaya idan aka kwatanta da ƙimar farko)
| Kashi | Yawan marasa lafiya | HS-LDL | Jimlar Chs | HS-HDL | |
| Waka | 13 | -7 | -5 | 3 | |
| 10 MG | 17 | -52 | -36 | 14 | |
| 20 MG | 17 | -55 | -40 | 8 | |
| 40 MG | 18 | -63 | -46 | 10 | |
| Kashi | Yawan marasa lafiya | TG | Xc- wadanda ba HDL ba | Apo v | Apo AI |
| Waka | 13 | -3 | -7 | -3 | 0 |
| 10 MG | 17 | -10 | -48 | -42 | 4 |
| 20 MG | 17 | -23 | -51 | -46 | 5 |
| 40 MG | 18 | -28 | -60 | -54 | 0 |
Tebur 2. Sakamakon-kashi-mai-ƙarfi a cikin marasa lafiya da ke ɗauke da cututtukan jini (nau'in IIb da na IV bisa ga ƙididdigar Fredrickson) (ƙimar matsakaicin ƙaranci idan aka kwatanta da darajar farko)
| Kashi | Yawan marasa lafiya | TG | HS-LDL | Jimlar Chs | |
| Waka | 26 | 1 | 5 | 1 | |
| 10 MG | 23 | -37 | -45 | -40 | |
| 20 MG | 27 | -37 | -31 | -34 | |
| 40 MG | 25 | -43 | -43 | -40 | |
| Kashi | Yawan marasa lafiya | HS-HDL | Xc- wadanda ba HDL ba | Xc- VLDL | TG- VLDL |
| Waka | 26 | -3 | 2 | 2 | 6 |
| 10 MG | 23 | 8 | -49 | -48 | -39 |
| 20 MG | 27 | 22 | -43 | -49 | -40 |
| 40 MG | 25 | 17 | -51 | -56 | -48 |
Ingancin asibiti
Inganci a cikin marasa lafiyar manya tare da hypercholesterolemia tare da ko ba tare da hypertriglyceridemia ba, ba tare da la'akari da launin fata, jinsi ko shekaru ba, incl. a cikin marasa lafiya da ciwon sukari mellitus da familial hypercholesterolemia. A cikin 80% na marasa lafiya tare da nau'in IIa da IIb hypercholesterolemia (bisa ga rarrabuwa na Fredrickson) tare da matsakaicin farawa na LDL-C game da 4.8 mmol / L, yayin ɗaukar ƙwayar a cikin kashi 10 MG, maida hankali ne na LDL-C ya kai ƙasa da 3 mmol / L.
A cikin marasa lafiya tare da heterozygous familial hypercholesterolemia suna karɓar rosuvastatin a kashi 20-80 mg / rana, an lura da ingantaccen tasiri na bayanan lipid. Bayan titration zuwa kashi na yau da kullun na 40 MG (makonni 12 na jiyya), an lura da rage yawan LDL-C ta 53%. A cikin 33% na marasa lafiya, an cimma daidaituwa na LDL-C da ƙasa da 3 mmol / L.
A cikin marasa lafiya tare da hyzycholesterolemia na homozygous familial na karɓar rosuvastatin a kashi 20 MG da 40 MG, matsakaicin raguwa a cikin taro na LDL-C ya kasance 22%.
A cikin marasa lafiya tare da hypertriglyceridemia tare da maida hankali na farko na TG daga 273 mg / dL zuwa 817 mg / dL, karɓar rosuvastatin a cikin allurai na 5 MG zuwa 40 MG 1 lokaci / rana don makonni 6, an rage yawan yawan TG a cikin jini jini (duba tebur 2 )
Ana lura da sakamako mai ƙari a hade tare da fenofibrate dangane da taro na TG kuma tare da acid nicotinic acid a cikin rage ƙwayar lipid (fiye da 1 g / rana) dangane da maida hankali kan HDL-C.
A cikin binciken METEOR, rosuvastatin farjin a hankali ya rage yawan ci gaba na matsakaicin matsakaiciyar ƙwayar intima-media (TCIM) don kashi 12 na ƙwayar carotid idan aka kwatanta da placebo. Idan aka kwatanta da ƙididdigar tushe a cikin rukunin rosuvastatin, an lura da raguwa a cikin mafi girman TCIM ta 0.0014 mm / shekara idan aka kwatanta da haɓakar wannan mai nuna ta 0.0131 mm / shekara a cikin rukunin placebo. Zuwa yau, dangantakar kai tsaye tsakanin raguwa a cikin TCIM da raguwa a cikin haɗarin haɗarin jijiyoyin zuciya ba a nuna su ba.
Sakamakon binciken na JUPITER ya nuna cewa rosuvastatin ya rage haɗarin ci gaba da rikice-rikice na zuciya tare da rage haɗarin dangi na 44%. An lura da tasirin magani bayan farkon watanni 6 na amfani da miyagun ƙwayoyi. An sami raguwar ƙididdigar yawan kashi 48% cikin haɗuwa, ciki har da mutuwa daga cututtukan zuciya, bugun jini da infarction myocardial, raguwar 54% a cikin abin da ya faru na rashin ƙarfi ko rashin haihuwa mai rauni, da kuma 48% ragewa a cikin rauni mai rauni ko maras rai. Gabaɗaya yawan mace-mace ya ragu da 20% a cikin rukunin rosuvastatin. Bayanan martaba a cikin marasa lafiya da ke ɗaukar rosuvastatin 20 MG sun kasance daidai da bayanin martabar aminci a cikin rukunin placebo.
Analogues na miyagun ƙwayoyi Rosucard
Analog ne mai rahusa daga 529 rubles.
Mai masana'anta: Biocom (Russia)
Siffofin Saki:
- Allunan 10 MG, 30 inji mai kwakwalwa., Farashin daga 110 rubles
- Allunan 20 MG, guda 30., Farashin daga 186 rubles
Umarnin don amfani
Atorvastatin shiri ne na sakin kwamfutar hannu wanda aka yi niyya don magani da rigakafin cututtukan zuciya. Contraindicated a lokacin daukar ciki, lactation kuma a cikin yara 'yan shekaru 18 da haihuwa.
Analog ne mai rahusa daga 161 rubles.
Mai masana'anta: Pharmstandard (Russia)
Siffofin Saki:
- Allunan 10 MG, 30 inji mai kwakwalwa., Farashin daga 478 rubles
- Allunan 20 MG, 30 inji mai kwakwalwa., Farashin daga 790 rubles
Umarnin don amfani
Akorta wani magani ne na Rasha wanda ke samuwa a cikin kwamfutar hannu kuma an yi niyya don maganin cututtukan cututtukan zuciya. Contraindicated a cikin ciki da kuma lactation. Akwai sakamako masu illa.
Analog mai rahusa daga 176 rubles.
Mai masana'anta: AstraZeneca (UK)
Siffofin Saki:
- Allunan 10 MG, 7 inji mai kwakwalwa., Farashin daga 463 rubles
- Allunan 20 MG, 30 inji mai kwakwalwa., Farashin daga 790 rubles
Umarnin don amfani
Krestor magani ne don magance cututtukan cututtukan zuciya. A matsayin abu mai aiki, ana amfani da rosuvastatin a cikin adadin 5 MG. don kwamfutar hannu 1 Akwai contraindications da sakamako masu illa.
Analog mai rahusa daga 180 rubles.
Mai masana'anta: Gideon Richter (Hungary)
Siffofin Saki:
- Allunan 5 MG, pc 30., Farashin daga 459 rubles
- Allunan 20 MG, 30 inji mai kwakwalwa., Farashin daga 790 rubles
Umarnin don amfani
Mertenil magani ne na rage yawan nono daga kasar Hungary wanda ya danganta da rosuvastatin. Aka sayar a cikin katun katunan 30 na allunan. Babban alamomi don alƙawarin: hypercholesterolemia, hypertriglyceridemia (nau'in IV a cewar Fredrickson), kazalika da rigakafin manyan cututtukan zuciya (bugun jini, bugun zuciya, farfadowa na jijiya).
Analog mai rahusa daga 223 rubles.
Mai masana'anta: Krka (Slovenia)
Siffofin Saki:
- Tab. p / obol. 5 MG, 30 inji mai kwakwalwa., Farashin daga 416 rubles
- Allunan 20 MG, 30 inji mai kwakwalwa., Farashin daga 790 rubles
Umarnin don amfani
Roxera magani ne mai sauƙin rage zafin nama na samar da Slovenia. Akwai shi a cikin nau'ikan Allunan waɗanda ke ɗauke da rosuvastatin a sashi na 5 zuwa 20 MG. Amfani da shi don tsayar da cutar hawan jini.
Analog ne mai rahusa daga 371 rubles.
Mai masana'anta: Belupo (Croatia)
Siffofin Saki:
- Allunan 10 MG 14 inji mai kwakwalwa., Farashin daga 268 rubles
- Allunan 20 MG, 30 inji mai kwakwalwa., Farashin daga 790 rubles
Umarnin don amfani
Rosistark magani ne na zubar da jini na kungiyar statins. Ya hada da kwayoyin rosuvastatin. Lowers cholesterol da gabobin sa, yana kawar da dattijuwar cutarwa. Yana da kayan kariya na rigakafi da ƙwarin antioxidant. An tsara shi don hypercholesterolemia, ƙara triglycerides a cikin jini, don kawar da ci gaban atherosclerosis da rage haɗarin haɗarin jijiyoyin bugun gini. Duk samfuran da ke dauke da rosuvastatin ana amfani dasu a kowane lokaci na rana, ba tare da la'akari da yawan abincin ba. Cikakken contraindications don amfani sune cututtukan cututtuka masu mahimmanci na kodan da hanta, myopathy, mata na shekarun haihuwa ba tare da maganin hana haihuwa ba. Daga cikin sakamako masu illa, waɗanda suka fi yawa sune maƙarƙashiya, ciwon kai, da rauni na jijiya.
Analog mai rahusa daga 305 rubles.
Mai masana'anta: Aegis (Hungary)
Siffofin Saki:
- Tab. p / obol. 5 MG, 28 inji mai kwakwalwa., Farashin daga 334 rubles
- Tab. p / obol. 10 mg, 28 inji mai kwakwalwa., Farashin daga 450 rubles
Umarnin don amfani
Rosulip wani rosuvastatin ne na ajin statin. An samar dashi, kamar Rosart, da duk rosuvastatins na yanzu, a cikin nau'ikan Allunan. Lokacin ɗauka, yana rage matakan haɓaka mai ƙarfi na cholesterol, ƙarancin mai ƙarfi na ƙananan ƙarfi (LDL, VLDL), triglycerides, da ƙara yawan lipoproteins mai yawa, wanda ke kare jikin ɗan adam daga rikicewar zuciya da kwakwalwa. Inganta kaddarorin jini, yana hana samuwar atherosclerotic plaques. Alamu don amfani, sashi da tsarin kulawa, contraindications da sakamako masu illa suna da alaƙa gaba ɗaya ga Rosart da Rosistark, tunda duk waɗannan magungunan suna dauke da rosuvastatin.
Kayan magunguna
Don zaɓar analogues na Rosucard, kuna buƙatar gano menene abubuwan da suke da shi. Ana samun magungunan a cikin nau'ikan Allunan 10 MG. A miyagun ƙwayoyi rage taro da low yawa lipoproteins, ko "mummunan" cholesterol, da kuma ƙara yawan babban lipoproteins yawa. Babban sinadaran aiki shine rosuvastatin.
Ana amfani dashi don atherosclerosis, hyperlipidemia, hypercholesterolemia. Ana iya amfani dashi azaman prophylactic game da cututtukan zuciya.
Wajibi ne a hada magungunan shan kwayoyi tare da rage kiba, wato abinci mai gina jiki, wanda a ciki ake rage yawan kitse.
Hanyar magani tare da miyagun ƙwayoyi ya kamata ya wuce wata ɗaya. An zabi kashi daya-daya ta likita. Ana gudanar da magani ne a karkashin kulawar matakan cholesterol na glucose na mai haƙuri, saboda akwai haɗarin haɓaka nau'in ciwon sukari na type 2 na mellitus bayan kammala karatun.
Ba za ku iya ɗaukar mutane masu irin waɗannan cututtukan ba:
- hanta da koda,
- ciwon kai
- hawan jini.
Hakanan, ba a ba da shawarar maganin ba yayin daukar ciki, lactation, yara 'yan ƙasa da shekara 18, tare da rashin haƙuri na lactose.
Ba za a iya haɗaka jiyya tare da barasa ba da kuma rigakafi na Cyclosporin. Ya kamata a ba da hankali ga marasa lafiya da suka haura shekaru 65 da mutanen tsere na Mongoloid.
Yayin shan magani, illolin da ke tattare da wadannan abubuwan na iya faruwa:
tsananin farin ciki- ciwon kai
- tashin zuciya
- maƙarƙashiya
- asthenia
- rashin lafiyan dauki
- karancin aikin koda.
tsananin farin cikiKudin maganin da ke dauke da allunan 30 shine 870 rubles.
Analogues na miyagun ƙwayoyi
Akorta alama ce ta Rosucard, ko kwatankwacin Rasha. Yana da abu guda mai aiki. Akwai shi a cikin allunan 10 da 20 MG. Alamomi, magunguna da kuma tasirin sakamako iri daya ne da na Rosucard. Farashin maganin yana da rahusa - 653 rubles.
Atomax Russia da Indiya ne ke samar da maganin. Babban sinadari mai aiki shine atorvastatin alli trihydrate. Akwai shi a cikin kwamfutar hannu.
Ana amfani dashi don manyan cholesterol. Contraindicated a cikin yara, masu juna biyu da kuma lactating mata. Ya kamata a kula da hankali don keta hakkin a hanta, hauhawar jini, rikicewar endocrine, buguwa mai taushi, amai.
Magani na iya haifar da irin wannan sakamako:
- asthenia
- rashin bacci
- ciwon kai
- kunne a cikin kunnuwa
- gumi
- zazzabi.
Aikin magani shine makonni 2-4. Farashin magungunan shine 323 rubles.
Lipitor - kwayayen dake rage cholesterol, samar da Jamusanci. Abunda yake aiki shine atorvastatin. Farashin shine 630 rubles.
Pravastatin alama ce ta haɗin gwiwa tsakanin Rasha da Slovenia. Abunda yake aiki shine pravastatin sodium. Tare da babban cholesterol, ƙwayar tana da tasiri mai banƙyama a kanta. Hakanan yana rage adadin triglycerins, low lipoproteins mai yawa.
Ana amfani dashi don rigakafin maimaita bugun zuciya, cututtukan zuciya da jijiyoyin jini, angina pectoris. Amfani da shi azaman haɗin haɗin abinci don rage yawan rage kiba.
An ba da magani ga cutar hanta, ciki da lactation, shan barasa.
Aikin ne daga kwanaki 7 zuwa 28. Ana aiwatar dashi tare da kulawa da kulawa akai-akai game da matakan rage kiba.
Farashin magungunan shine 650 rubles don allunan 10.
Kuna iya maye gurbin Rosucard tare da allunan da aka yi da Romaniyanci - Simvastol. Abubuwan da ke aiki da miyagun ƙwayoyi shine simvastatin. Yana rage jini cholesterol. Aikin magani shine watanni 1-1.5.
An nuna shi don tasirin cholesterol mai hauhawa da cututtukan zuciya.
Jiyya tare da miyagun ƙwayoyi yana contraindicated a cikin irin waɗannan cututtuka:
- fargaba
- cutar hanta
- tashin hankali
- kwanan nan raunin da ya faru da aiki.
Zai iya haifar da irin wannan sakamako:
rashin tsoro- tashin zuciya
- tsananin farin ciki
- anemia
- Karuwa da ESR
- rage iko.
rashin tsoroAllunan ya kamata su bugu da daddare, suna shan ruwa da kyau. Ba'a bada shawarar haɗuwa tare da irin waɗannan magunguna:
- jami'in antifungal
- nicotinic acid
- cytostatics
- anticoagulants.
Hakanan ya kamata a ɗauka a cikin zuciya cewa yin amfani da ruwan 'ya'yan itacen innabi yana haɓaka sakamakon maganin.
Farashin magungunan shine 211 rubles.
Ariescor aboki ne na Rasha. Abinda ke ciki na allunan sun hada da:
- simvastatin
- maganin ascorbic acid
- citric acid
- lactose.
Farashin analog na Rasha shine 430 rubles.
Zokor - magani ne akan simvastatin. Ana amfani dashi don manyan cholesterol. Countryasar da ke samar da samfurin ita ce Netherlands. Alamu da contraindications iri daya ne. Farashin shine 572 rubles.
Kafin maye gurbin kwayoyin dake rage cholesterol, ya kamata koyaushe ka nemi likita.
Madadin Rasha da ƙasashen waje na Rosucard
Analog ne mai rahusa daga 529 rubles.
Atorvastatin magani ne na hypocholesterolemic, babban bangaren wanda shine wani nau'in hanawar H HC-CoA reductase inhibitor: atorvastatin. Waɗannan sune capsules 10, 15 da 20 mg. An nuna shi don hypercholesterolemia na kowane asali, cututtukan gado - dysbetalipoproteinemia, hypertriglyceridemia, wasu nau'o'in hyperlipidemia, cututtukan tsarin zuciya. Sashi bai dogara da tsere ba kuma yana ɗaukar nauyin 10 zuwa 80 MG na miyagun ƙwayoyi kowace rana. Contraindicated a cikin hanta gazawar, rashin haƙuri ga abubuwan da ke cikin miyagun ƙwayoyi, lokacin daukar ciki da lactation, da kuma ƙarƙashin shekarun 18. Rashin jituwa da magunguna da yawa.
Rosistark (Allunan) Rating: 40 Top
Analog ne mai rahusa daga 371 rubles.
Rosistark kwatankwaci ne na Rosucard, ana samunsa a allunan 10, 20 da 40 mg. An wajabta shi don cututtukan guda ɗaya kamar sauran magunguna, abu mai aiki wanda shine rosuvastatin, a cikin alamominsa da contraindications kuma basu bambanta da su ba. Ba shi da tasiri ga halayen psychomotor, saboda haka ana iya amfani da shi daga direbobin mota da mutanen da ke sarrafa wasu kayan aiki.
Analog mai rahusa daga 305 rubles.
Ana samo Rosulip a cikin allunan. Abunda yake aiki: rosuvastatin. Sashi: 5 MG, 10 MG, 20 MG, 40 MG. Kasancewa mai hanawa na HMG-CoA reductase, rosuvastatin yana rage cholesterol jini da triglycerides kuma an wajabta shi don atherosclerosis, hypercholesterolemia wanda ke haifar da gado da cututtukan da suka danganci shekaru, hauhawar jini. Ingancin wannan abu yana da girma a cikin mutanen tsere na Mongoloid, sabili da haka, an tsara magungunan da ke jikinsa da taka tsantsan. Sashi na yau da kullun, dangane da cutar da tsananin ƙarfinsa, ya kasance daga 10 zuwa 40 MG.
Analog mai rahusa daga 223 rubles.
Roxera gaba daya ta zo daidai da alamomi tare da sauran masu maye gurbin Rosucard waɗanda ke ɗauke da rosuvastatin, suna zuwa ta hanyar Allunan tare da sashi na 5, 10, 15 ko 20 mg. Ana iya ganin ingantaccen jerin abubuwan contraindications da sakamako masu illa na gefen sama, kuma alamomi don amfani. Ba'a amfani dashi a hade tare da cyclosporine da wasu magunguna.
Kayan magunguna
Abu mai aiki a cikin ƙwayar Rosucard rosuvastatin, yana da kaddarorin don hana ayyukan ragectase, da rage haɗarin ƙwayoyin mevalonate, wanda ke da alhakin haɗin cholesterol a farkon matakan a cikin ƙwayoyin hanta.
Wannan maganin yana da tasirin maganin warkewar lipoproteins, yana rage haduwarsu ta kwayoyin hanta, wanda yake rage girman rage yawan kwayoyin halittar abinci mai narkewa a cikin jini kuma yana kara yawan narkewar kwayoyin halittar jini mai yawa.
Pharmacokinetics na miyagun ƙwayoyi Rosucard:
- Mafi girman abubuwan aiki a cikin abubuwan jini na jini, bayan shan allunan, suna faruwa ne bayan sa'o'i 5,
- A bioavailability na miyagun ƙwayoyi shine 20.0%,
- Bayyanar Rosucard a cikin tsarin ya dogara da karuwar sashi,
- 90.0% na Rosucard magani yana ɗaure ga furotin na plasma, mafi yawan lokuta, shine furotin albumin,
- Metabolism na miyagun ƙwayoyi a cikin sel hanta a farkon matakin ne game da 10.0%,
- Don cytochrome isoenzyme A'a. P450, aiki mai aiki na rosuvastatin yana canzawa,
- An cire maganin da 90.0% tare da feces, ƙwayoyin hanji suna da alhakin shi,
- 10.0 an ware shi ta amfani da sel koda tare da fitsari,
- Magungunan magunguna na Rosucard ba su dogara da nau'in shekarun masu haƙuri ba, har ma da jinsi. Magungunan suna aiki iri ɗaya, duka a jikin saurayi da kuma a cikin tsofaffi, a cikin tsufa kawai yakamata ya zama mafi ƙarancin ƙwayar cuta don maganin babban kwayar cholesterol a cikin jini.
Ana iya jin tasirin warkewar farko na miyagun ƙwayoyi na kungiyar Rosacard rukuni na statins bayan shan miyagun ƙwayoyi na kwanaki 7. Ana iya ganin girman tasirin hanyar magani bayan shan kwayoyin a cikin kwanaki 14.
Babban yanayin shan magungunan shine don bincika bayanin a bayyane kuma ya bi dukkan shawarwarin likitan, to sakamakon tasirin magani zai zama mafi yawa.
Kudin maganin Rosucard ya dogara ne da masu kirkirar maganin, ƙasar da aka yi maganin. Analogues na Rashan na miyagun ƙwayoyi suna da rahusa, amma tasirin magani bai dogara da farashin maganin ba.
Rikicin Rasha na Rosucard, kamar yadda ya rage ƙididdigar a cikin cholesterol na jini, har da magungunan kasashen waje.
Farashin magungunan Rosucard a cikin Tarayyar Rasha:
- Farashin rosucard 10.0 MG (Allunan 30) 550,00 rubles,
- Magungunan Rosucard 10.0 MG (90 inji mai kwakwalwa.) 1540.00 rubles,
- Asalin magani Rosucard 20.0 mg. (30 tab.) 860.00 rubles.
Rayuwar shiryayye da amfanin allunan Rosucard shekara guda ne daga ranar da aka sake su. Bayan ranar karewa, magani ya fi kyau kar a sha.
Alamu don amfani
Kafin amfani da ilimin magani don rage babban ma'auni a cikin cholesterol na jini, ya zama dole don amfani da hanyoyin da ba magunguna ba na tasirin tasirin lipoproteins a cikin jiki:
- Aiki da aiki,
- Kauda duk abubuwanda ke haifar da tashin hankali (shan giya da jarabar nicotine),
- Dietauki abincin rigakafi don rage lipids na jini da ƙona ƙarin fam.
Idan duk hanyoyin magance ƙwayoyin cuta marasa ƙwayoyi ba su fitar da sakamako ba, to likitan ya yanke shawara game da nadin magungunan ƙungiyar statin.
A cewar likitoci da yawa, yakamata a dauki statins a hade tare da tsarin abinci na cholesterol, wanda zai taimaka ga mafi ingancin raguwar adabin cholesterol na dan kankanen lokaci.
Sau da yawa, yayin daidaitawa da maida hankali na cholesterol a cikin jini, Ina amfani da kwayoyi waɗanda ke da sinadaran rosuvastatin mai aiki.
A cikin umarnin da aka yi amfani da shi, wanda mai ba da magani ya ba da, an wajabta maganin Rosucard don irin waɗannan cututtukan cututtukan jiki:
- Heterozygous hypercholesterolemia,
- Cakuda nau'in hypercholesterolemia,
- Ilimin ilimin firamari na tsoka,
- Hyperriglycerinemia,
- Pathology na jini atherosclerosis.
Yin amfani da miyagun ƙwayoyi Rosucard a cikin matakan kariya na irin waɗannan cututtuka:
- Matakan hanyoyin kariya don bugun zuciya
- Tare da tsinkayar jiki zuwa ga cigaban angina pectoris,
- Yin rigakafin cututtukan hanji na ischemia,
- Don hana ci gaban cututtukan jijiyoyin bugun gini na atherosclerosis,
- Don rigakafin ma'aunin hawan jini a cikin hauhawar jini.
- Bayan tiyata a kan jijiyoyin jini.
Sau da yawa, yayin daidaitawa da maida hankali na cholesterol a cikin jini, Ina amfani da kwayoyi waɗanda ke da sinadaran rosuvastatin mai aiki.
Contraindications
Ba za a iya amfani da shi ba don rage ƙididdigar cholesterol a cikin jinin marasa lafiya da irin wannan rikice-rikice da cututtukan jikin mutum:
- Babban hankalin mutum ga abubuwan da ke cikin aikin Rosucard,
- Aikin hanta mai aiki
- Ciwan hanta da koda
- A cikin tsananin rashin ƙarfi na yara,
- Tare da karuwar ƙididdigar transaminase,
- Tare da Pathology, myopathy,
- A lokacin daukar ciki a cikin mata,
- A lokacin ciyar da jariri tare da madarar nono.
Hakanan, ba a sanya Rosucard ga matan masu haihuwa ba wadanda basa amfani da maganin hana haihuwa.
Akwai contraindications zuwa alƙawarin da miyagun ƙwayoyi Rosucard, tare da matsakaicin sashi a cikin kwamfutar hannu guda ɗaya na aikin rosuvastatin mai nauyin 400 milligrams:
- Tare da shan giya na yau da kullun, ba a sanya magungunan Rosucard ba,
- Mai tsananin rashin ƙarfi na matsin matsakaici mai aiki na ƙwaƙwalwar koda,
- Tare da hadarin da ke tattare da cutar sankara,
- Ilimin halin dan adam ilimin halin dan adam, a yanayin da ake fadi,
- Jiyya na babban cholesterol tare da kwayoyi na ƙungiyar fibrate,
- Sepsis a cikin jini
- Hypotension marasa lafiya
- Bayan tiyata a jiki,
- A ci gaba na seizures a cikin jiki da kuma pathologies na tsoka nama,
- Pathology of epilepsy,
- Rashin lalacewa a cikin tafiyar matakai na rayuwa a cikin jiki, wanda ke faruwa a cikin mummunan tsari.
Kar a sha magani ga mata yayin daukar ciki
Yadda za a ɗauki rosucard?
Ya kamata a ɗauka miyagun ƙwayoyi Rosucard a baki tare da isasshen adadin ruwa. An haramta tauna kwamfutar hannu, saboda ana hade shi da membrane wanda ke narkewa a cikin hanjin.
Kafin fara karatun warkewa tare da magungunan Rosucard, mai haƙuri dole ne ya bi tsarin abincin da ke cikin anticholesterol, kuma dole ne abincin ya kasance tare da dukkan jiyya tare da mutum-mutumi, gwargwadon aikin mai aiki na rosuvastatin.
Likita ya zaɓi zaɓi daban-daban ga kowane mara lafiya, gwargwadon sakamakon gwaje-gwajen gwaje-gwaje, da kuma haƙurin mutum na jikin mai haƙuri.
Likita ne kawai, idan ya cancanta, ya san yadda ake maye gurbin allunan Rosucard. Gyaran gyaran ƙwayar cuta da maye gurbin miyagun ƙwayoyi tare da wani magani yana faruwa ba a farkon mako biyu ba daga lokacin gudanarwa.
Maganin farko na maganin Rosucard bai kamata ya wuce milligram 10.0 ba (kwamfutar hannu ɗaya) sau ɗaya a rana.
A hankali, a cikin aikin jiyya, idan ya cancanta, a cikin kwanaki 30, likita ya yanke shawarar ƙara yawan sashi.
Don haɓaka kullun na maganin Rosucard, ana buƙatar waɗannan dalilai masu zuwa:
- Wani mummunan nau'in hypercholesterolemia, wanda ke buƙatar matsakaicin sashi na 40,0 milligrams,
- Idan a ma'aunin milligram na 10.0, lipogram ya nuna raguwar cholesterol. Likita ya kara sashi na 20,0 milligram, ko kuma nan da nan kaso mafi yawa,
- Tare da matsanancin rikicewar bugun zuciya,
- Tare da wani babban ci gaba na ilimin halayyar cuta, atherosclerosis.
Wasu marasa lafiya, kafin kara yawan sashi, suna buƙatar yanayi na musamman:
- Idan ƙarancin ƙwayar ƙwayar hanta tayi daidai da ƙimar Kid-Pugh na 7.0, to ba za'a bada shawarar sashi na Rosucard ba,
- Game da gazawar koda, zaku iya fara karatun magani tare da allunan 0.5 a kowace rana, kuma bayan hakan zaku iya ƙara yawan sashi zuwa milligram 20,0, ko ma zuwa sigar matsakaicin,
- A cikin gazawar haɓaka mai girma, ba a yarda da statins,
- Matsakaici mai rauni na gawar koda. Matsakaicin adadin magungunan Rosucard ba likitoci ne suka umarta ba,
- Idan akwai haɗarin ƙwayar cuta, myopathy kuma yana buƙatar farawa tare da Allunan 0.5 kuma an haramta yawan kashi 40.0 milligrams.
Yin gyare-gyare a jiki yayin jiyya
Yawan damuwa
Overaukar magunguna Rosucard ba ya shafar magungunan magunguna. Canje-canje daga abin sama da ya faru bai faruwa. Babu wasu ƙwararrun dabaru da aka kirkira don kawar da yawan magungunan ƙwayar cuta ta Rosucard.
Wajibi ne a kula da alamun cutar yawan kwayoyin cuta. Wajibi ne a lura da alamomin ayyukan ƙwayar hanta koyaushe kuma, idan ya cancanta, ɗauki matakai.
Amfani da maganin hemodialysis, tare da yawan ƙwayar statin, ba shi da tasiri a jiki.
Yin hulɗa tare da wasu kwayoyi
A cikin ƙasashe da yawa, ana sayar da magunguna ne kawai kamar yadda likita ya umarta, muna da magunguna da yawa a cikin zagayawa kyauta, wanda ke ƙarfafa yawancin marasa lafiya suyi gwajin lafiyarsu kuma su ɗauki magunguna azaman maganin kansu.
Wannan ya wadatar da sakamako mai wahala ga jiki, saboda marasa lafiya basu yin la’akari da duk matsalolin illolin da kwayoyi ke haifarwa a jiki. Hakanan, ba mutane da yawa sun san yadda magunguna ke hulɗa da juna yayin shan su.
Tebur yana nuna sakamakon gwada magunguna Rosucard lokacin hulɗa tare da wasu magunguna:
| Nau'in magani da yadda yake a kullun | kashi na yau da kullun na Rosucard | canje-canje a cikin magani na AUC Rosucard |
|---|---|---|
| magani Atazanavir 300.0 MG da magani Ritonavir 100.0 MG sau ɗaya. / rana., don kwanaki 8. | 10.0 mg sau daya. | Sau 3.1 yana ƙaruwa. |
| Cyclosporine daga 75.0 MG sau biyu a rana. har zuwa 200.0 MG sau biyu a rana., rabin shekara | 10.0 mg | mafi girma a 7.1 p. |
| magani Lopinavir 400.0 mg / magani Ritonavir 100.0 mg sau biyu / rana. | 20.0 MG | karuwa a cikin 2.1 p. |
| Allunan Simeprivir guda 150.0 MG 1 lokaci / rana. | 10.0 mg | 2.80 p. Mafi girma |
| Eltrombopak 75.0 mg sau ɗaya / rana. | 10.0 mg | mafi girma a 1.6 p. |
| miyagun ƙwayoyi gemfibrozil 600.0 mg sau biyu / rana. | 80.0 MG | karuwa daga 1.90 p. |
| Tipranavir 500.0 MG da Ritonavir 200.0 MG | 10.0 mg | karuwa daga 1.40 p. |
| magani Darunavir 600.0 mg da magani Ritonavir 100.0 mg sau biyu | 10.0 mg | sama da 1.50 p. |
| magani Itraconazole 200.0 MG sau ɗaya | 10.0 mg | karuwa daga 1.4 p. |
| Dronedarone 400.0 MG sau biyu kowace rana | babu bayanai | karuwa a cikin 1.2 p. |
| magani Fozamprenavir 700.0 MG da magani Ritonavir 100.0 MG sau biyu | 10.0 mg | 1.4 p. Mafi girma |
| magani Aleglitazar 0.30 MG | 40,0 mg | tsaka tsaki |
| Ezetimibe 10.0 mg sau ɗaya | 10.0 mg | tsaka tsaki |
| Fenofibrate 67.0 MG sau uku | 10.0 mg | tsaka tsaki |
| Silymarin 140.0 MG sau uku | 10.0 mg | babu canji |
| Ketoconazole 200.0 MG sau biyu | 80.0 MG | babu canji |
| Rifampicin 450.0 mg sau ɗaya | 20.0 MG | babu canji |
| magani erythromycin 500.0 MG sau hudu | 80.0 MG | 20.0% raguwa |
| magani Fluconazole 200.0 MG sau ɗaya | 80.0 MG | tsaka tsaki |
| Allunan Baikalin 50,0 MG sau uku | 20.0 MG | 47,0% ƙananan |
Amfani mai kyau na Rosucard da antacids, tare da luminium da magnesium, rage taro akan statin sau 2. Idan kayi amfani da waɗannan kwayoyi tare da tazara tsakanin 2 zuwa 3, to, rage mummunan tasirin zai ragu.
Lokacin haɗuwa da ci daga allunan rosucard da kwayoyi tare da masu hana kariya, to, AUC0-24 yana ƙaruwa sosai.
Ga mutanen da ke kamuwa da kwayar cutar, kwayar cutar kwayar cutar kwayar cutar kwayar cutar kwayar cuta ce kuma tana da rikitarwa.
Side effects
Idan kun dauki miyagun ƙwayoyi daidai, kuma ku bi duk shawarar likita ta hanyar ɗaukar Rosucard, har ma da abinci mai gina jiki, to za a iya guje wa mummunan sakamako na miyagun ƙwayoyi a jiki.
Amma masana'anta har yanzu sun rubuta wasu maganganu marasa kyau na jikin mutum wajen shan kwayoyin:
| tsarin jikin mutum da gabobinsa | quite sau da yawa | ba sau da yawa sosai | lokaci-lokaci | keɓaɓɓen lokuta | mita ba a sani ba |
|---|---|---|---|---|---|
| tsarin tafiyar jini | Pathology na hemostatic tsarin - thrombocytopenia | ||||
| ilimin cututtukan endocrine | hyperglycemia - ciwon sukari | ||||
| cibiyoyi na tsarin juyayi | Soreness a kai, | ƙwaƙwalwar ƙwaƙwalwar ajiya | Damuwar bacci, | ||
| · Haushi, | Pathology na polyneuropathy. | ||||
| rashin daidaituwa game da motsi. | |||||
| rashin hankalin mutum | Jihar tawayar | ||||
| Jin tsoro | |||||
| Rashin kulawa. | |||||
| narkewa a ciki | Ciwon ciki a ciki, | ||||
| Zawo gudawa | |||||
| maƙarƙashiya | |||||
| ilimin cututtukan ƙwayar cututtukan ƙwayar cututtukan ƙwayar ƙwayar ƙwayar cuta - ƙwayar ƙwayar ƙwayar cuta. | |||||
| tsarin numfashi | Mai tsananin bushe tari | ||||
| Rage numfashi | |||||
| It Abu ne mai wahala yin numfashi. | |||||
| kwayoyin cutar hepatic | kwayar transaminase a cikin kwayoyin halittar hepatic ta hauhawa | kumburi a cikin ƙwayoyin hanta - hepatitis | |||
| fata fata | Fata fatar jiki, | Johnson-Stevenson ciwo | |||
| Ya saukar da rash, | |||||
| Itching mai tsananin gaske. | |||||
| kwarangwal da tsoka | pathology myalgia | cututtukan mahaifa | pathology arthralgia | Tendon katako, | |
| · Necrotic myopathy. | |||||
| yankin yanki | gabobin jiki | ||||
| tsarin urinary | ilimin cututtukan uroral - hematuria | ||||
| yanayin gaba daya na take hakkin | ilimin cututtukan asthenia | kumburi a fuska da wata gabar jiki. |
Mitar bayyanuwar illolin mummunan sakamako akan jikin mutum ya dogara da dalilai da yawa:
- Indexara yawan ma'aunin glucose a cikin jini (a kan komai a ciki na 5.6 mmol a kowace lita kuma sama),
- BMI ya fi kilo 30 a kowace mita,
- Babban jini triglyceride index,
- Hawan jini.
Shirye-shirye, wanda rosuvastatin yake aiki a matsayin aiki mai aiki, ana samarwa da yawa. Ana samarwa a cikin ƙasashe da yawa, ciki har da masana'antun Rasha.
Abubuwan analogues na gida na magungunan Rosucard suna da araha sosai fiye da analogues na kasashen waje.
Har ila yau, magunguna masu alaƙa da Rasha sun yi tasiri a cikin rage ƙirar cholesterol, har da magungunan kasashen waje, waɗanda ke cikin ɓangaren farashi mai tsada.
Doctor ne kawai zai iya zaɓar maganin analog don magani. Analogues na miyagun ƙwayoyi Rosucard, da abubuwan da ya samo asali:
- Magungunan Torvacard,
- Maganin Mertenil,
- Statin Rosuvastatin,
- Da miyagun ƙwayoyi Krestor,
- Roxer magani
- Generic Atorek,
- Magunguna Zokor,
- Magungunan Rosuvakard.
Kammalawa
Za'a iya amfani da magani na Rosucard a cikin magance ƙwayar cholesterol a cikin jini, kawai a hade tare da abinci mai gina jiki na anticholesterol.
Rashin bin tsarin abincin zai jinkirta tsarin warkarwa kuma ya lalata mummunan tasirin miyagun ƙwayoyi a jiki.
Ba za a iya amfani da miyagun ƙwayoyi Rosucard a matsayin magani na kansa ba, kuma lokacin da aka tsara shi an hana shi da daidaituwa don daidaita matakan allunan, kazalika da canza tsarin kulawa.
Yuri, dan shekara 50, Kaliningrad: statins sun rage mini cholesterol a al'ada cikin makonni uku. Amma bayan wannan, lissafin ya sake tashi, kuma dole in sake yin magani tare da kwayoyin maganin statin.
Sai kawai lokacin da likita ya canza magunguna na baya zuwa Rosucard, Na lura cewa waɗannan kwayoyin ba kawai zasu iya dawo da cholesterol na al'ada ba, har ma ba su kara shi da kyau ba bayan hanya ta warke.
Natalia, 57 years old, Ekaterinburg: cholesterol ya fara tashi yayin haila, kuma abincin ba zai iya rage shi ba. Na kasance ina shan kwayoyi na rosuvastatin na tsawon shekaru 2. Wata 3 da suka wuce, likita ya maye gurbin magunguna na baya tare da allunan Rosucard.
Na ji sakamakonsa nan da nan sai na ji daɗi kuma nayi mamakin cewa na iya rasa kilo kilo 4 na nauyi.
Nesterenko N.A., likitan zuciya, Novosibirsk Ina wajabta gumaka ga majiyyata ne kawai lokacin da aka yi kokarin amfani da dukkan hanyoyin rage cholesterol kuma akwai babban hadarin bunkasa cututtukan zuciya, da kuma atherosclerosis.
Statins suna da yawa sakamako masu illa ga jiki, wanda ke shafar yanayin rayuwar marasa lafiya.
Amma ta yin amfani da magungunan Rosucard a cikin al'ada, Na lura cewa marasa lafiya sun daina gunaguni game da mummunan tasirin da ke tattare da statins. Yarda da duk shawarwari don amfani zai samar wa mara lafiya da mafi ƙarancin halayen jiki.
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