Magungunan ƙwayar cuta ta hanyar magani - umarnin, analogues da waɗanda ke maye gurbin sake dubawa

Formetin sashi na tsari - Allunan: 500 MG - zagaye, lebur-Silinda, fari, tare da daraja da bevel, 850 MG da 1000 MG - oval, biconvex, fari, tare da daraja a gefe ɗaya. Shiryawa: fakitin bakin ciki - guda 10 kowannensu, a cikin wani kwali na kunshin 2, 6 ko 10, fakiti 10 da 12 kowannensu, a cikin kwali na kunshin 3, 5, 6 ko 10 fakiti.

• abu mai aiki: metformin hydrochloride, a cikin kwamfutar hannu 1 - 500, 850 ko 1000 mg,
• ƙarin abubuwan haɗin da abun cikin su don Allunan 500/850/1000 mg: magnesium stearate - 5 / 8.4 / 10 mg, croscarmellose sodium (primellose) - 8 / 13.6 / 16 mg, povidone (povidone K-30, matsakaici matsakaitan kwayoyin polyvinylpyrrolidone ) - 17/29/34 mg.

Pharmacodynamics

Metformin hydrochloride - abu mai aiki na mantuwa - wani abu ne wanda ke hana gluconeogenesis a cikin hanta, yana inganta amfani da gllu, yana rage kamuwa da glucose daga cikin hanji, kuma yana kara yawan jijiyoyin jikin mutum zuwa insulin. A wannan yanayin, ƙwayar ba ta shafi ɓoyewar insulin ta hanyar ƙwayoyin beta na pancreas, kuma ba ya haifar da haɓakar halayen cututtukan jini.

Metformin yana rage ƙananan lipoproteins mai yawa da triglycerides a cikin jini. Rage nauyi ko tsayar da jiki.

Saboda iyawar ƙwaƙwalwar ƙwaƙwalwar ƙwayar plasminogen mai kunnawa, ƙwayar tana da tasirin fibrinolytic.

Pharmacokinetics

Bayan sarrafa bakin, metformin a hankali yana sha daga cikin gastrointestinal fili. Bayan ɗaukar daidaitaccen kashi, bioavailability kusan 50-60%. Matsakaicin ƙwayar plasma ya kai cikin awa 2.5

A zahiri ba a ɗaura shi da sunadaran plasma. Yana tarawa a cikin kodan, hanta, tsokoki da gyada mai narkewa.

Halfwayar rabin rayuwa tana daga awa 1.5 zuwa 4.5. thewayoyin ta canza shi ba canzawa. A cikin marasa lafiya waɗanda ke fama da rauni na aikin haya, tarawar metformin na iya faruwa.

Contraindications

• mai ciwon sukari ketoacidosis,
• precoma / coma mai ciwon sukari
• aikin hanta mai rauni,
• mai rauni daskararction,
• mummunan cututtuka
• na yanzu ko tarihin lactic acidosis,
• fitsari, matsanancin ƙwayar cuta, saurin ɓarkewar rauni na zuciya, gazawar zuciya da gazawar numfashi, giya mai ƙwanƙwasa da sauran cututtuka / yanayi waɗanda zasu iya taimakawa ci gaban lactic acidosis,
• mummunan rauni ko tiyata lokacin da aka nuna maganin insulin,
• m barasa guba,
• manne wa tsarin abinci mai yawan jini (kasa da 1000 kcal / day),
• ciki da lactation,
• Nazarin X-ray / radioisotope ta amfani da aidin-dauke da matsakaiciyar matsakaici (a cikin kwanaki 2 kafin nan da kwana 2 bayan),
• rashin hankali ga miyagun ƙwayoyi.

Ba'a bada shawarar Formethine ga mutane sama da shekara 60 da suke yin aiki na zahiri ba, tunda suna da haɗarin haɓakar lactic acidosis.

Umarnin don amfani da formetin: hanya da sashi

Allunan magungunan suna nuna alamar amfani da baka. Ya kamata a ɗauke su gaba ɗaya, ba tare da tauna ba, tare da isasshen ruwan, lokacin abinci ko bayan abincin.

An saita takaddara mafi kyau ga kowane mai haƙuri daban-daban kuma an ƙaddara shi da matakin glucose a cikin jini.

A matakin farko na maganin, ana daukar 500 MG sau 1-2 a rana ko 850 MG sau ɗaya a rana. A gaba, ba fiye da lokaci 1 a mako guda, ana sannu a hankali ana ƙara yawan kashi. Matsakaicin da za'a iya yarda dashi na Formetin shine 3000 MG kowace rana.

Tsofaffi kada su wuce maganin yau da kullun na 1000 mg. A cikin rikice-rikice na wucin gadi saboda babban haɗarin lactic acidosis, ana bada shawarar rage yawan.

Side effects

• daga tsarin endocrine: lokacin da aka yi amfani dashi da ƙarancin allurai - hypoglycemia,
• daga gefen metabolism: da wuya - lactic acidosis (yana buƙatar karɓar magani), tare da tsawaita amfani - hypovitaminosis B₁₂ (malamborption)
• daga tsarin narkewa: dandano mai narkewa a cikin bakin, gudawa, rashin ci, tashin zuciya, ciwon ciki, zafin jiki, amai,
• daga gabobin hemopoietic: da wuya - megaloblastic anemia,
• halayen rashin lafiyan: fatar fata.

Yawan damuwa

Yawan overform na metformin na iya haifar da mummunar lactic acidosis. Lactic acidosis zai iya haɓakawa saboda yawan ƙwayoyi a cikin marasa lafiya da ke fama da rauni na aikin koda. Alamomin farko na wannan yanayin sune: raguwar zazzabi a jiki, rauni gaba ɗaya, jin zafi a cikin tsokoki da ciki, zawo, tashin zuciya da amai, reflex bradyarrhythmia, da raguwar hauhawar jini. A nan gaba, tsananin farin ciki, saurin numfashi, tsinkayyar kaifin kwakwalwa, coma yana yiwuwa.

Idan bayyanar cututtukan lactic acidosis ya bayyana, ya kamata ka dakatar da ɗaukar allunan alluran kuma nan da nan mara lafiyar ya kamata a kwantar da shi a asibiti. An tabbatar da bayyanar cutar dangane da bayanan tattarawar lactate. Hemodialysis shine mafi inganci don cire lactate daga jiki. Treatmentarin magani yana nuna alama.

Umarni na musamman

Ya kamata a kula da marasa lafiya da suke karbar maganin metformin a koyaushe don aikin koda. Akalla sau 2 a shekara, kuma a game da myalgia, ana buƙatar ƙayyadaddun abubuwan da ke cikin lactate plasma.

Idan ya cancanta, za a iya ƙaddamar da abu tare da abubuwan da suka samo asali na maganin sulfonylurea. Koyaya, yakamata a gudanar da kulawa ƙarƙashin kulawa da matakan glucose na jini.

A lokacin jiyya, ya kamata ka guji shan giya, tunda ethanol yana ƙara haɗarin lactic acidosis.

Tasiri a kan ikon tuka motoci da abubuwa masu rikitarwa

Dangane da umarnin, Formmetin, wanda aka yi amfani dashi azaman ƙwayoyi guda ɗaya, baya shafar taro na hankali da saurin halayen.

Dangane da batun amfani da lokaci guda na sauran wakilai na hypoglycemic (insulin, abubuwan sulfonylurea ko wasu), akwai yuwuwar yanayin hypoglycemic wanda ikon yin tuƙi mota da shiga cikin ayyukan haɗari masu haɗari waɗanda ke buƙatar saurin halayyar kwakwalwa da halayen jiki, kazalika da ƙara kulawa, daɗaɗɗa.

Hulɗa da ƙwayoyi

Sakamakon hypoglycemic na metformin zai iya inganta ta hanyar abubuwan da suka haifar da maganin sulfonylurea, magungunan anti-mai kumburi, abubuwan gado na clofibrate, inhibitors enzyme, inhibitors na monoamine oxidase, masu hana jini adrenergic, abubuwan oxygentetracycline, acarbose, cyclophosphamide, insclophosphamide insulin.

Abubuwan da aka samo na nicotinic acid, hormones thyroid, sympathomimetics, maganin hana haihuwa, thiazide da loop diuretics, glucocorticosteroids, abubuwan asali na phenothiazine, glucagon, epinephrine na iya rage tasirin hypoglycemic na metformin.

Cimetidine yana rage jinkirin kawar da metformin kuma, a sakamakon haka, yana ƙara haɗarin lactic acidosis.

Yiwuwar lactic acidosis yana ƙaruwa tare da amfani da ethanol lokaci guda.

Magungunan cationic da aka ɓoye a cikin tubules (quinine, amiloride, triamteren, morphine, quinidine, vancomycin, procainamide, digoxin, ranitidine) gasa ga tsarin jigilar tubular, saboda haka zasu iya ƙara yawan haɗarin metformin da kashi 60% tare da tsawaita amfani.

Nifedipine yana haɓaka ɗaukar yawan ƙwayar metformin, yana rage jinkirin sa.

Metformin na iya rage tasirin maganin antumagulants da aka samo daga coumarin.

Analogues na Formmetin sune: Bagomet, Gliformin, Gliformin Prolong, Glucofage, Glucofage Long, Diasphor, Diaformin OD, Metadiene, Metfogamma 850, Metfogamma 1000, Metformin, Metformin Zentiva, Metformin Long, Metformin Long Canon, Metformin S-Metform-Sform Canon, Metformin-Richter, Metformin-Teva, Siofor 500, Siofor 850, Siofor 1000, Sofamet, Longin Long, Formin Pliva.

Menene aka ba da formetin?

Formmetin kwatanci ne na ƙwayar Jamusanci ta Glucophage: tana ɗauke da abu guda ɗaya mai aiki, tana da zaɓuɓɓuka iri ɗaya, da kuma nau'ikan allunan. Nazarin da kuma ra'ayoyin masu haƙuri da yawa sun tabbatar da irin tasirin magungunan biyu ga masu ciwon sukari. Wanda ya kirkiro kamfanin Formmetin shine rukunin kamfanonin Rasha na kamfanin Pharmstandard, wanda a yanzu ya mamaye wani babban matsayi a kasuwar hada magunguna.

Kamar Glucophage, ana iya samun Formmetin a cikin sigogi 2:

A halin yanzu, ana amfani da metformin ba kawai don maganin ciwon sukari ba, har ma don sauran cututtukan cuta tare da juriya na insulin.

Areasarin wuraren amfani da miyagun ƙwayoyi Formetin:

1. Yin rigakafin ciwon sukari A Rasha, an yarda da amfani da metformin a haɗari - a cikin mutane masu babban yiwuwar kamuwa da ciwon sukari.
2. Formmetin yana baka damar tayar da ovulation, sabili da haka, ana amfani dashi lokacin da ake shirin daukar ciki. Recommendedungiyar Americanungiyar Endocrinologists ta Amurka ta ba da shawarar maganin a matsayin magani na farko-layi na ƙwayar polycystic. A cikin Rasha, wannan alamar don amfani har yanzu ba a yi rijista ba, saboda haka, ba a cikin umarnin.
3. Formethine na iya inganta yanayin hanta tare da steatosis, wanda yawanci yana haɗuwa da ciwon sukari kuma yana ɗayan kayan haɗin jini.
4. Rage nauyi tare da juriya insulin. A cewar likitoci, Allunan kwalayen kara ingancin abinci mai karancin kalori kuma suna iya sauƙaƙe tsarin rage nauyi a cikin marasa lafiya masu kiba.

Akwai shawarwari da za a iya amfani da wannan maganin azaman wakili na antitumor, da kuma rage hanzarin tsufa. Har yanzu ba a yi rajistar waɗannan alamomin ba, tunda sakamakon karatun na farko ne kuma suna buƙatar sake dubawa.

Aikin magunguna

Abubuwa da yawa suna haifar da tasirin rage ƙwayar sukari na Formetin, wanda babu wanda ke shafar cutar kai tsaye. Jagororin yin amfani da su suna nuna ma'anar tsarin aikin ƙwaƙwalwa mai yawa:

1. Yana haɓaka hankalin insulin (yana aiki sosai a matakin hanta, zuwa ƙarancin jijiya a cikin tsokoki da mai), wanda ke haifar da sukari rage sauri bayan cin abinci. Ana samun wannan sakamako ta hanyar ƙara yawan ayyukan enzymes waɗanda ke cikin masu karɓar insulin, kazalika da haɓaka aikin GLUT-1 da GLUT-4, waɗanda suke jigilar glucose.
2. Yana rage samarda glucose a cikin hanta, wanda a cikin mellitus na sukari yana karuwa har sau 3. Saboda wannan iyawa, allunan Formethine suna rage sukarin azumi da kyau.
3. Yana kawo cikas tare da shan glucose daga hanji, wanda zai baka damar rage haɓakar glycemia na postprandial.
4. Yana da ƙananan tasiri anorexigenic. Saduwa da metformin tare da gastrointestinal mucosa na rage yawan ci, wanda hakan ke haifar da asarar nauyi a hankali. Tare da raguwar juriya na insulin da raguwa a cikin samar da insulin, an sauƙaƙe hanyoyin rarrabu ƙwayoyin mai.
5. Tasiri a jikin jijiyoyin jini, yana hana haɓakar cerebrovascular, cututtukan zuciya. An kafa shi cewa yayin jiyya tare da Formetin, yanayin ganuwar tasoshin jini yana inganta, fibrinolysis yana motsawa, kuma ƙirƙirar ƙwanƙwasa jini yana raguwa.

Sashi da yanayin ajiya

Koyarwar ta ba da shawarar cewa, don samun biyan diyya ga masu ciwon sukari da rage yiwuwar tasirin da ba a son su, ƙara yawan ƙwayar Formmetin a hankali. Don sauƙaƙe wannan tsari, ana samun allunan a cikin zaɓuɓɓukan sashi guda 3. Formmetin na iya ƙunsar 0.5, 0.85, ko 1 g na metformin. Formetin Long, sashi ya ɗan bambanta, a cikin kwamfutar hannu na 0.5, 0.75 ko 1 g na metformin. Wadannan bambance-bambance sun kasance ne saboda sauƙin amfani, tunda ana ɗaukar Formetin yana da matsakaicin adadin 3 g (3 Allunan na 1 g kowane), yayin da Formetin Long - 2.25 g (3 Allunan 0.75 g kowace).

An adana tsari na shekaru 2 daga lokacin samarwa, wanda aka nuna akan fakitin da kowane bugu na miyagun ƙwayoyi, a zazzabi har zuwa digiri 25. Sakamakon allunan za a iya raunana ta hanyar dogon lokaci game da radiation na ultraviolet, don haka umarnin yin amfani da shawarar yana bada shawarar sanya blister a cikin kwali.

Yadda ake ɗaukar FORMETINE

Babban dalilin masu ciwon sukari sun ki yin magani tare da Formetin kuma analogues din shi ne rashin jin daɗi da ke tattare da narkewar abinci. Da muhimmanci a rage yawan su da ƙarfin su, idan ka bi sosai a kan shawarwarin daga umarnin don fara aiki da metformin.

Karamin lokacin farawa, zai zama mafi sauqi ga jiki ya daidaita da maganin. Yanayin aiki yana farawa da gg 0,5, ba sau da yawa tare da 0.75 ko 0.85 g .. Ana ɗaukar allunan bayan cin abinci mai ban sha'awa, zai fi dacewa da yamma. Idan cutar rashin lafiya da safe ta fara damuwa a farkon jiyya, zaku iya rage yanayin tare da ɗan abin sha da ruwan lemon da ba a ɗauka ba ko kuma fure mai fure.

Idan babu sakamako masu illa, ana iya karuwa kashi a cikin sati. Idan magungunan ba su da haƙuri, koyarwar tana ba da shawara don jinkirta karuwar sashi har zuwa ƙarshen alamun rashin jin daɗi. A cewar masu ciwon sukari, wannan yakan ɗauki makonni 3.

A hankali ga yawan ciwon sukari yana ƙaruwa sau da yawa har sai an daidaita ƙwayar cutar glycemia. Theara yawan zuwa 2 g yana haɗuwa da raguwar aiki a cikin sukari, to, tsari yana raguwa da mahimmanci, don haka ba koyaushe bane mai hankali ya tsara mafi girman sashi. Koyarwar ta hana shan allunan formmetin a cikin matsakaicin adadin don tsofaffin masu ciwon sukari (sama da shekara 60) da kuma marasa lafiya da haɗarin haɗari na lactic acidosis. Matsakaicin da aka ba su izini shine 1 g.

Likitocin sun yi imanin cewa idan mafi kyawun kashi na 2 g ba ya samar da ƙimar glucose mai ƙima ba, ya fi ma'ana don ƙara wani magani ga tsarin kulawa. Mafi sau da yawa, yana zama ɗayan abubuwan da suka samo asali na sulfonylurea - glibenclamide, glyclazide ko glimepiride. Wannan haɗin yana ba ku damar ninka tasiri na jiyya.

Side effects

Lokacin ɗaukar Formetin, waɗannan masu yiwuwa ne:

• matsalolin narkewa. Dangane da sake dubawa, mafi yawan lokuta ana bayyana su cikin tashin zuciya ko zawo. Commonlyarancin yau da kullun, masu ciwon sukari suna koka game da ciwon ciki, haɓakar haɓakar gas, dandano mai ƙarfe a cikin komai a ciki,
• malabsorption na B12, an lura dashi kawai tare da tsawaita amfani da wani abu,
• lactic acidosis abu ne mai matukarkasuwa amma yana da matukar hatsarin rikitar cutar sankara. Zai iya faruwa ko dai tare da wucewar metformin, ko kuma tare da keta alfarma daga jininsa,
• rashin lafiyan halayen a cikin nau'i na fatar fata.

Ana daukar Metformin magani ne mai babban lafiya. Yawancin sakamako masu illa (fiye da 10%) sune cuta kawai na narkewa, waɗanda suke na gida cikin yanayi kuma basa haifar da cututtuka. Hadarin wasu tasirin da ba'a so ba shine fiye da 0.01%.

Likita na Kimiyyar Kimiyya, Shugaban Cibiyar Nazarin Diabetology - Tatyana Yakovleva

Na yi shekaru da yawa ina nazarin ciwon sukari. Yana da ban tsoro yayin da mutane da yawa suka mutu, har ma da yawa suna zama masu rauni saboda cutar sankara.

Na yi hanzarin ba da labari mai daɗi - Cibiyar Binciken Endocrinological na Kwalejin Kimiyya ta Rasha ta sami nasarar haɓaka maganin da ke warkar da ciwon sukari gaba ɗaya. A yanzu, ingancin wannan magani yana gab da kashi 98%.

Wani albishir: Ma'aikatar Lafiya ta tabbatar da ɗaukar wani shiri na musamman wanda zai biya diyyar magunguna mai yawa. A Rasha, masu ciwon sukari har sai 18 ga Mayu (m) samun shi - Don kawai 147 rubles!

Mashahurai analogues

A matsayin bayanin tunani, muna ba da jerin magunguna da aka yi wa rajista a cikin whichungiyar Tarayyar Rasha, waxanda suke analogues na Formetin da Formetin Long:

A karkashin sunan samfurin Metformin, ana kuma samar da kwayar cutar ta Atoll, Rafarma, Biosynthesis, Vertex, ballanta, Izvarino Pharma, Medi-Sorb, Gideon Richter, Metformin Long - Canonfarma, Biosynthesis. Kamar yadda ake iya gani daga tebur, mafi yawan metformin a cikin kasuwar Rasha asalin asalin Indiya ne. Ba abin mamaki bane cewa ainihin Glucophage, wanda aka ƙera gaba ɗaya a Faransa, ya fi zama sananne tsakanin marasa lafiya da masu ciwon sukari.

Masana'antu ba sa haɗa musamman da mahimmancin ƙasar asalin metformin. Abubuwan da aka saya a Indiya cikin nasara sun isa har ma da tsayayyen ingancin iko kuma kusan ba su bambanta da na Faransa ɗaya ba. Hatta manyan kamfanoni a Berlin-Chemie da Novartis-Pharma suna ɗaukar shi da inganci sosai kuma suna da amfani kuma suna amfani da shi don yin allunan.

Formine ko Metformin - wanda yafi kyau (shawarar likitoci)

Daga cikin abubuwan da ake kira Glucofage, ana samarwa a cikin Rasha, babu wanda ya bambanta a cikin ikon ciwon sukari. Kuma Formin, da yawa analogues na kamfanoni daban-daban da ake kira Metformin suna da tsari iri ɗaya kuma iri ɗaya na tasirin sakamako.

Yawancin masu ciwon sukari suna sayan metformin na Rasha a cikin kantin magani, ba su kula da wani masana'anta ba. A cikin takardar sayan magani, ana nuna sunan abu mai aiki kawai, saboda haka, a cikin kantin magani zaka iya samun kowane samfurin analogues da aka lissafa a sama.

Metformin sanannen magani ne mai rahusa. Ko da ainihin Glucofage yana da ɗan ƙanƙantar da farashi (daga 140 rubles), analogues na gida har ma da araha. Farashin kayan kunshin Formetin yana farawa a 58 rubles don allunan 30 tare da mafi ƙarancin sashi kuma yana ƙare a 450 rubles. don allunan 60 na Formwafin Tsarin 1 g.

Bayanin sigar da nau'in fitarwa

Tabletaya daga cikin kwamfutar hannu ya ƙunshi:

matsakaici nauyi povidone

Ana samun wadataccen formetin a cikin gilashin gilashi na allunan 100, 60 ko 30.
Launi na allunan suna da fari, kuma fom ɗin ya dogara da sashi na babban abu. A 500 MG, suna da siffar zagaye zagaye na silima tare da daraja da chamfer. Hakanan, sashi na 1000 da 850 MG shine “formin”. Allunan a wannan yanayin suna convex da m. Suna tare da haɗarin gefe ɗaya.

Makoma

Ana amfani da maganin “Formin” don magance wani nau'in cututtuka. Wato, a gaban nau'in ciwon sukari na 2, a cikin lokuta masu ƙuraje masu rikitarwa, lokacin da abincin ba ya taimakawa ci gaba da matakin sukari na al'ada, koda a hade tare da sulfonylurea. Hakanan tasiri shine "Formin" don asarar nauyi.

Yadda za a ɗauka?

Likita ya zabi kashi wannan maganin bisa gwargwadon yawan glucose a cikin jini. Dole ne a gudanar da maganin na baka bayan abinci, yayin shan ruwa mai yawa kuma ba tare da fallasa kwamfutar hannu don maganin ta inji ba. Kamar yadda muka riga muka ambata a sama, an tsara sashi gwargwadon yawan abubuwan glucose a cikin jini. Zai fara da ƙaramin adadin 0.5 g ko 0.85 g kowace rana. Kwana biyu bayan fara magani tare da wannan magani, ana lura da kullun abun da ke cikin metformin a cikin jini. Idan ya cancanta, a hankali zaku iya ƙara yawan zuwa mafi girman darajar. Ya yi daidai da 3 grams.

Tunda yawanci ana lura da ci gaban lactic acidosis a cikin tsofaffi, matsakaicin matakin yau da kullun shine 1 g a garesu Hakanan, adadin ƙwayar yana raguwa yayin tashin hankali na rayuwa, don hana rashin lafiyan, bayyana a cikin nau'in fatar fata, da sauran sakamako masu illa waɗanda za a tattauna a kasa.

Side sakamako

Abunda ya faru da irin wannan alamu marasa dadi kamar '' ƙarfe '' a cikin bakin, amai, amai, zawo, gas, ƙarancin ci yana buƙatar dakatar da amfani da maganin cutar kai tsaye kuma tuntuɓi gwani. Yin amfani da miyagun ƙwayoyi na dogon lokaci yana haifar da cin zarafi ko dakatar da shan sha na bitamin B₁₂, wanda ke haifar da tarawa a jikin na ƙarshen, yana haifar da hypovitaminosis. A cikin lokuta masu saɓani, akasin haɓaka - megaloblastic B₁₂karancin jini. Tare da kashi ba daidai ba, hypoglycemia yana yiwuwa. Allergic halayen a cikin nau'i na fatar fata na iya faruwa. Sabili da haka, magungunan "Tsarin", sake dubawa wanda akan dacewar amfani dashi, sunsha banban, yakamata likitan ku ya tsara.

Sakamakon wannan magani a cikin ikon sarrafa abubuwan motsa jiki da abubuwan hawa

A wannan yanayin, akwai kuma wasu abubuwa. Sakamakon "Kayan tsari" akan ikon sarrafa kayan aiki da sufuri yana faruwa ne kawai idan an yi amfani dashi tare da kwayoyi waɗanda ke shafar ayyukan aiki, suna buƙatar amsawa da sauri da kuma ƙara yawan kulawa. Wannan yana da mahimmanci a sani.

Yi amfani da shi don shayarwa da ciki

Magungunan "Formin", umarnin don amfani da wanda aka bayyana a cikin wannan rubutun, yana da nau'in fallasa ga tayi "B" bisa ga FDA. A lokacin daukar ciki, ana iya ɗaukar wannan magani. Koyaya, amfaninsa na iya zama a wasu yanayi. Wato, lokacin da ake tsammanin sakamako daga wannan rashin lafiyar zai wuce gaban haɗarin haɗari ga tayin. Wasu takamaiman takamaiman karatu game da amfani da irin wannan magani kamar "miyagun ƙwayoyi" ba a gudanar dasu lokacin daukar ciki ba. A lokacin jiyya kamata ya daina shayarwa. A kowane hali, ya kamata ku nemi shawarar kwararrun likita.

"Kayan tsari": analogues

Akwai kuɗi da yawa na wannan nau'in. Misalin “Formin” shirye-shirye ne wadanda suka ƙunshi asalinsu a matsayin babban bangaren metformin hydrochloride. Misali magungunan masana’antun Rasha ne: Vero-Metformin, Gliformin, Metformin, Metformin Richter, da na kasashen waje - Glucofag, Glucofage da Glucofage Long (Faransa), Langerin "(Slovakia)," Metfogamma "tare da magunguna daban-daban na abubuwa masu aiki 0,100, 0,500 da 0,850 g (Jamus).

Sharuɗɗan da yanayin ajiya

Akwai wasu yanayi a wannan. Magungunan "Formin" yana da iko, don haka ana ba da izini ne kawai ta hanyar takardar sayan magani kuma yana buƙatar ajiya a zazzabi a cikin ɗakuna, daga isa ga yara da hasken rana. Rayuwar rayuwar shiryayye shine shekaru 2.

Matsakaicin farashin miyagun ƙwayoyi "Formmetin" an saita shi gwargwadon sashi: daga 59 rubles. kowace blister 0.5 g, 133 rubles. don 0.85 g da 232 rubles. na 1 g.

Tsarin saki, abun da aka shirya da marufi

Ana samar da "Kayan tsari" a cikin nau'i mai farin launi biconvex tare da layin rarrabuwa a gefe ɗaya. A kan kunshin, ana nuna sashi - 500 MG, 850 MG ko 1000 MG, dangane da maida hankali kan abu mai aiki.

Allunan 10 na ciki suna cikin blister, duka a cikin ayarin kwali akwai katunan 30, 60 ko 100 Allunan. Umarnin don amfani an haɗe.

Babban sinadaran aiki shine metformin hydrochloride. Wannan fili ana rarrabe shi azaman ƙarni na uku na biguanide. A matsayin kayan taimako, povidone yana dauke da matsakaicin nauyi na matsakaitan kwayoyin halitta, sodium croscarmellose da magnesium stearate.

INN masana'antun

"Formmetin" yana ɗaya daga cikin kasuwancin kasuwanci, sunan wanda ba na ƙasa ba shine metformin hydrochloride.

Maganin ne ya samar da masana'antar cikin gida - kamfanin samar da magunguna na Rasha Pharmstandard.

Farashin ya dogara da adadin allunan a cikin kunshin da kuma sashi. A matsakaici, allunan 30 na 500 MG kowane farashi 70 rubles, kuma a sashi na 850 MG - 80 rubles.

Manuniya da contraindications

Babban nuni ga alƙawarin shine ciwon sukari na 2. Wannan maganin yana dacewa musamman ga marasa lafiya masu kiba a cikinsu wanda sarrafa abinci da aikin jiki baya haifar da sakamako. Za a iya ɗauka tare da haɗin gwiwa tare da abubuwan samo asali na sulfonylurea. Magungunan suna tasiri sosai tare da matsala ta hyperglycemia da kuma tare da wuce kima.

Kodayake Formentin shine mafi amintaccen magani a tsakanin dukkanin magungunan hypoglycemic, yana da adadin contraindications:

• rashin ƙarfi ga metformin ko wasu abubuwan maganin,
• hadarin lactic acidosis,

• gurbataccen hanta ko aikin koda,
• barasa, a cikin rashin barasa maye,
• mai saurin kamuwa da cuta da tafiyar matakai,
• ketoacidosis, maganin ketoacidotic prema ko coma:
• kasancewa a rage yawan kalori,
• tarihin bugun jini ko bugun zuciya.

Tare da tsananin ƙone fata raunuka, raunin da ya faru, insulin farji an wajabta wa masu ciwon sukari kafin ko bayan tiyata. Idan ya zama tilas a gudanar da karatun x-ray ta amfani da shirye-shiryen aidin kwanaki da yawa kafin kuma bayan, ba a amfani da maganin.

GASKIYA! Ya kamata a yi amfani da hankali a cikin masu ciwon suga (sama da 65), tunda akwai haɗarin cutar lactic acidosis.

Umarnin don amfani (sashi)

Mafi ƙarancin adadin kayan aiki wanda aka wajabta a farkon jiyya shine 500-850 mg / day (1 kwamfutar hannu). A tsawon lokaci, ana daidaita adadi. Matsakaicin maganin wariyarwa shine 3000 MG / rana, kuma ga tsofaffi marassa lafiya - 1000 mg / day. Aauki kashi ɗaya na miyagun ƙwayoyi ana bada shawarar ta rarrabuwa zuwa allurai 2, rabin sa'a kafin cin abinci, tare da gilashin ruwa.

MUHIMMIYA! Kada ku jinkirta cin abinci bayan shan magani, saboda wannan yana ƙara haɗarin haɓaka yanayin hauhawar jini.

An saita tsawon lokacin aikin ta hanyar likita, ba za ku iya canza kwanakin ganawa da kansu ba.

Side effects

Abubuwan da ba a so ba kusan koyaushe suna faruwa a farkon farfaɗo, lokacin da jiki bai riga ya daidaita ba. A cikin 'yan makonni, dukkansu suna tafiya da kansu.

Mafi bayyanar cututtuka sune:

• daga narkewa kamar ciki - rikicewar bacci (maƙarƙashiya, zawo, asarar ci, jin zafi a ciki),
• halayen rashin lafiyan (rashes a kan fuska, wata gabar jiki ko ciki, itching da hypersensitivity na fata),
• rikicewar hormonal (yanayin hypoglycemic tare da ƙara yawan aiki na wasu magungunan hypoglycemic ko rashin bin shawarar likitan),
• rikicewar metabolism - lactic acidosis, gaggawa, buƙatar gaggawa cirewa),
• daga tsarin jini - Bem-defence anaemia.

Haihuwa da lactation

An haɗu da shi a cikin mata masu juna biyu da masu shayarwa, tunda babu bayanan kimiyya dangane da amincin amfanin sa a waɗannan lokutan. Idan akwai buƙata, to ana tura marasa lafiya zuwa maganin insulin. Lokacin da ake shirin yin juna biyu, mai haƙuri dole ne ya sanar da likita game da wannan don daidaita farjin.

Ba a gudanar da binciken amintacce game da damar “Marar” ta shiga cikin nono ba, saboda haka, matan da ke lasaftar da juna sun daina maganin. Idan kuwa ba zai yiwu a soke ba, sai an daina shayar da nono.

Yi amfani da ƙuruciya da tsufa

Kada a rubuta wa yara underan ƙasa da shekara 10, tunda babu bayanan aminci. A lokacin tsufa, ana nuna shi azaman monotherapy ko a hade tare da maganin insulin, amma tare da daidaita daidaitattun allurai gwargwadon bukatun da suka danganci shekaru.

A cikin tsofaffi marasa lafiya, maganin zai iya cutar da lafiyar kodan, don haka kuna buƙatar bincika aikin su akai-akai. Don yin wannan, aƙalla sau uku a shekara ta ƙayyade matakin ƙirar creatinine a cikin ƙwayar plasma.

Kwatanta tare da analogues

Akwai magunguna da yawa waɗanda suke da irin wannan tsarin aikin, wanda ya bambanta da yawan tasirin sakamako, contraindications da farashin. Wace magani ya kamata wajabta ta hanyar likita mai halartar.

Magungunan asali wanda aka dogara da metformin an yi shi a Faransa. Akwai ayyuka na yau da kullun da tsawan lokaci. Ya bambanta da "Kayan tsari" da sauran ilmin halitta a cikin ƙananan sakamako masu illa, amma farashinsa ya fi girma.

Sanya cikin lura da ciwon sukari, wanda ba a sarrafa shi ta hanyar maganin abinci. M, amma jerin contraindications da sakamako masu illa suna da faɗi sosai.

Baya ga metformin, ya ƙunshi wani bangaren aiki - vildagliptin. Sakamakon wannan, tasirin hypoglycemic yana da ƙarfi sosai fiye da na sauran analogues. Babban hasara shine babban farashin (daga 1000 rubles a kowace kunshin).

Ra'ayoyin masu ciwon sukari game da miyagun ƙwayoyi sun rarrabu. Marasa lafiya waɗanda suka ɗauke shi na dogon lokaci sun gamsu da sakamakon. Waɗanda suke amfani da shi kwanan nan suna magana game da sakamako masu illa na yau da kullun.

Valentina Sadovaya, 56 years old:

"Na dauki shekaru da yawa na ɗauki Gliformin, amma sakamakonsa ya fara rauni a kan lokaci. “Formin” ya juya ya zama cancantar cancantar - a kan komai a cikin sukari na ciki ba ya tashi sama da 6 mmol / l. A cikin makonnin farko na shigowa, an lura da rikicewar stool, amma komai ya wuce da sauri. Na yi matukar farin ciki da rahusa. "

Peter Kolosov, dan shekara 62:

“Likita ya dauke ni zuwa Formetin makonni kadan da suka gabata. A wannan lokacin, bayyanar cututtuka da yawa da ba a so sun bayyana: rauni, danshi, tashin zuciya, da kuma rikicewar stool. Wannan yana haifar da ƙarancin lafiya, matsaloli a wurin aiki. Wataƙila, zan tambaye ka don ba ni wani magani a kaina. ”

Formethine yana da tasiri don sarrafa T2DM, musamman a cikin marasa lafiya masu kiba. Da farko, sakamako masu illa na iya faruwa, amma tare da lokaci suka wuce. Amfanin magani shine ƙarancin kuɗaɗinsa. Kafin shan, kuna buƙatar tuntuɓi likitanku.

Alamu don amfani

An nuna magunguna ga masu kiba da masu kiba da gazawar maganin rage cin abinci, wahala ciwon sukari Nau'ikan 2 waɗanda ba a kwatanta su da hali zuwa ketoacidosis.

Don haka, ba a ba da umarnin Formmetin don asarar nauyi ba, kodayake lokacin shan maganin, nauyin marasa lafiya da gaske yana raguwa. Magungunan yana da inganci a hade tare da maganin insulin tare da furta kibahalin juriya insulin.

Umarnin don amfani da formetin (hanya da sashi)

Dole ne likita ya ƙayyade yawan maganin ta hanyar daban bayan cikakken ƙididdigar matsayin lafiyar mai haƙuri da tsananin cutar.

Koyaya, umarnin don amfani da Formetin yana nuna matsakaicin farkon warkewar maganin yau da kullun - daga 500 zuwa 1000 MG / rana.

Za'a iya aiwatar da daidaituwa na wannan sashi a cikin hanyar karuwa bayan mafi ƙarancin kwanaki 15 bayan fara magani tare da kula da matakan tilastawa glucose a cikin jinin mai haƙuri. Yawan maganin yana maganin matsakaita 1,500-200 mg / day, amma bai kamata ya wuce milimita 3,000 / rana ba. Ga tsofaffi marasa lafiya, matsakaicin adadin yau da kullun kada ya zama 1 g.

Don gujewa lactic acidosis don kula da marasa lafiya da cuta cuta na rayuwa Recommendedarancin magani ana bada shawara.

Ana ɗaukar allunan Formethine bayan abinci, za a iya raba nauyin yau da kullun zuwa kashi biyu don guje wa sakamako masu illa daga tsarin narkewa.

Haɗa kai

Ba da shawarar shan formethine tare da:

• Danazoldon ware karuwar cutarwar ƙarshen,
• Chlorpromazinedon gujewa kamuwa da cuta,
• Acarbase monoamine oxidase inhibitorsdaangiotensin yana canza enzyme, Abubuwan da suka dace na sulfonylureada Clofibrate, magungunan anti-inflammatory marasa steroidal, oxygentetracyclinedackers-masu hanawadon gujewa haɓaka kaddarorin metformin, wani sashi na formethine,
• Cimetidinewanda ke kawo saurin aiwatar da kawar da jiki metformin,
• maganin hana haihuwa, glucagon, thiazide diuretics, hormones na thyroid, abubuwan nicotinic acid da kuma phenothiazinedon hana rage aiki metfomina,
• abubuwan gado coumarin (anticoagulants)tunda metforminraunana tasirinsu.

Bugu da kari, haramun ne a sha magani a sha giya, kamar yadda wannan yana ƙara haɓaka damar ci gabalactic acidosis.

Ana buƙatar gyaran sashi na tilas bayan ko lokacin jiyya tare da maganin tari.

Ra'ayoyi game da formetin

Marasa lafiya suna wahala ciwon sukari kuma waɗanda suka gwada tasirin miyagun ƙwayoyi akan kansu, bar ra'ayoyi masu saɓani game da Formin akan majalisun. Ba duk marasa lafiya ke karɓar wannan maganin daidai ba.

Mutane da yawa a matsayin mara kyau factor ambaci wani m ban sha'awa jerin contraindications, kazalika da cewa a lokacin da shan wannan miyagun ƙwayoyi, dole ne su saka idanu a hankali da amfani da wasu na'urorin likita da zabi hadaddun magani wanda yake mai lafiya ga lafiya da rayuwa.

Formmetin: farashin a cikin kantin magani na kan layi

Allunan kwayan 500 na kwayar cuta guda 30.

FORMETIN 0.5 g 30 inji mai kwakwalwa. kwayoyin hana daukar ciki

FORMETIN 0.5 g 60 inji mai kwakwalwa. kwayoyin hana daukar ciki

Allunan 500 MG Allunan 60 inji mai kwakwalwa.

Allunan kwalaji 850 MG 30 inji mai kwakwalwa.

Allunan 1 g allunan 30 pcs.

FORMETIN 1 g 30 inji mai kwakwalwa. kwayoyin hana daukar ciki

Allunan 850 MG Allunan 60 inji mai kwakwalwa.

FORMETIN 0.85 g 60 inji mai kwakwalwa. kwayoyin hana daukar ciki

FORMETIN 1 g 60 inji mai kwakwalwa. kwayoyin hana daukar ciki

Allunan 1 g allunan 60 pcs.

Tab ɗin formethine. 1g n60

Tsararren tabo tare da tsawanta. sakin n / fursuna. 750mg No. 30

Tsarin foda na tsawon kwana 750 yana ci gaba da sakin allunan fim wanda aka sanya 30 inji mai kwakwalwa.

Tsararren tabo tare da tsawanta. sakin n / fursuna. 500mg No. 60

Tsarin tsari mai tsawo 500 MG yana tallafawa allunan sakin fim wanda aka rufe 60 inji mai kwakwalwa.

Tsararren tabo tare da tsawanta. sakin n / fursuna. 750mg No. 60

Formethine Long 750 MG ya ci gaba da sakin allunan fim wanda aka rufe 60 inji mai kwakwalwa.

Ilimi: Na farko Jami'ar Likita ta Jihar Moscow da aka sanya wa suna da I.M. Sechenov, ƙwararren "General Medicine".

Bayanai game da miyagun ƙwayoyi an samar da su duka, an bayar da su don dalilai na bayanai kuma baya maye gurbin umarnin hukuma. Kai magani yana da haɗari ga lafiya!

Yawan nauyin kwakwalwar mutum kusan kashi biyu cikin dari ne na nauyin jiki, amma yana cin kusan kashi 20% na iskar oxygen da ke shiga jini. Wannan hujja tana sanya kwakwalwar dan Adam matsanancin rauni don lalacewa ta hanyar karancin iskar oxygen.

Tare da ziyarar yau da kullun akan gado na tanning, damar samun ciwon fata yana ƙaruwa da 60%.

Matsakaicin rayuwar lefties ya kasa da nisanci.

Ko da zuciyar mutum ba ta doke ba, to zai iya rayuwa na tsawon lokaci, kamar yadda masanin kifin nan na ƙasar Jan Revsdal ya nuna mana. “Motar” sa ya tsaya na tsawon awanni 4 bayan masun ɗin ya ɓace kuma ya faɗi cikin dusar ƙanƙara.

Domin faɗi har ma da mafi guntu kuma mafi sauƙaƙan kalmomi, muna amfani da tsokoki 72.

A yunƙurin fitar da mara lafiya, likitoci sukan yi nisa sosai. Don haka, alal misali, wani Charles Jensen a cikin shekarun daga 1954 zuwa 1994. ya tsira fiye da 900 aikin cirewar neoplasm.

Masana kimiyya daga Jami'ar Oxford sun gudanar da karatu da dama, a lokacin da suka kai ga matsayin cewa cin ganyayyaki na iya zama illa ga kwakwalwar dan Adam, saboda hakan yana haifar da raguwa a yawanta. Saboda haka, masana kimiyya sun bada shawarar kar a cire kifi da nama gaba daya daga abincin da suke ci.

Additionari ga mutane, halittu masu rai guda ɗaya a duniya - karnuka, suna fama da cutar sankara. Waɗannan ainihin abokanmu ne masu aminci.

Masana kimiyyar Amurka sun gudanar da gwaje-gwaje a kan mice kuma sun yanke hukuncin cewa ruwan kankana yana hana haɓakar atherosclerosis na hanyoyin jini. Groupaya daga cikin ƙungiyar mice sun sha ruwa a bayyane, ɗayan kuma ruwan 'ya'yan itace kankana A sakamakon haka, tasoshin rukunin na biyu sun kasance ba su da matattarar cholesterol.

Dangane da bincike, matan da ke shan tabarau na giya ko giya a mako guda suna da haɗarin kamuwa da cutar sankarar mama.

Shahararren magungunan "Viagra" an samo asali ne don maganin hauhawar jini.

Idan kun fada daga jaki, to, zaku sami damar juyar da wuyan ku fiye da wanda kuka faɗi daga doki. Kawai kada kuyi kokarin musun wannan magana.

Magungunan tari mai suna “Terpincode” yana daya daga cikin jagororin tallace-tallace, ba kwata-kwata saboda kayan aikinta.

Kowane mutum ba wai kawai ɗan yatsan yatsa bane, amma kuma yare.

Mabuɗin cakulan duhu huɗu sun ƙunshi adadin kuzari ɗari biyu. Don haka idan ba kwa son samun lafiya, zai fi kyau kada ku ci fiye da lobules biyu a rana.

Yawan ma'aikata da ke aiki a ofis ya karu sosai. Wannan halayyar musamman halayyar manyan birane ne. Aikin ofishi yana jan hankalin maza da mata.

Rashin sakamako da yanayi na musamman

Abubuwan da keɓaɓɓiyar halayen jikin mutum don ɗaukar miyagun ƙwayoyi "Formetin" sun haɗa da jerin alamun bayyanannu:

- "ƙarfe" dandano a bakin,

- tashin zuciya da amai,

- halayen rashin lafiyan (alal misali, rashes akan fata).

Idan yanayin da ke sama ya faru, dole ne a dakatar da wannan maganin nan da nan kuma nemi kwararrun likita. Bugu da ƙari, yana da mahimmanci a tuna cewa tare da tsawan magani tare da amfani da miyagun ƙwayoyi "Formmetin", cin zarafi ko dakatar da shaye-shayen bitamin B12 na iya faruwa, wanda ke haifar da hypovitaminosis wanda ba makawa (ƙasa da kullun zuwa kishiyar kishiyar - megaloblastic B12-rashin ƙarfi anaemia). Tare da ƙididdigar kuskuren adadin sashi, hypoglycemia na iya haɓaka.

Sakamakon tarin kwayoyin halitta na kwayar cuta mai suna “Formin” a jikin mutum, ya zama dole don kare mummunan sakamakon hakan. Don haka, don ware tarawar metformin da kuma rigakafin lactic acidosis, kuna buƙatar saka idanu sosai a kan aikin kodan da kuma gudanar da bincike don tantance adadin lactic acid a cikin jiki (aƙalla sau 2 a shekara). Kuma idan ciwo na rashin jin daɗi ya faru a cikin ƙwayar tsoka, ƙarin ƙarin binciken gaggawa wajibi ne.

Yin amfani da miyagun ƙwayoyi "Formmetin" yana buƙatar cikakken binciken bayanai game da hulɗa da miyagun ƙwayoyi. Don ware haɓakar ci gaban lactic acidosis da sauran sakamakon da ba a so, umarnin likita ya kamata a bi shi sosai kuma a bi umarnin yin amfani da shi. Misali, metformin mai aiki, wanda ke haɓaka sukari na jini, yana haɓaka tasirinsa a haɗe tare da magungunan anti-steroidal anti-inflammatory, kuma yayin shan tare da magungunan endocrine, hanawar hauhawar tsari zai yiwu.

Yawan shaye-shayen kwayoyi "Tsarin" na iya faruwa har ma da tsarin yau da kullun na 0.85 grams. Tabbas, tarawar metformin a cikin jikin mutum, wanda ke tsokane cigaban lactic acidosis, na iya faruwa ne sakamakon aikin najasa mai rauni. Babban bayyanar cututtuka a farkon matakan lactic acidosis sune halaye masu zuwa:

- raunin dukkan jiki,

- saukar da zafin jiki,

- jin zafi a ciki da tsokoki,

- saukar karfin jini,

- mai rauni da rashi.

Idan aka gano wannan alamar cutar a jikin kanta, yakamata mai haƙuri ya daina shan allunan “Formin” yaga likita. Lokacin tabbatar da bayyanar cututtuka na lactic acidosis, abu mai aiki da kuma lactic acid daga jiki, a matsayin mai mulkin, an cire shi ta hanyar hemodialysis tare da magani na alamomi na lokaci daya.

Mutane da yawa kwararru da kuma marasa lafiya amsa da tabbaci ga miyagun ƙwayoyi "Tsarin", duk da kasancewar wani kyakkyawan ban sha'awa jerin contraindications da sakamako masu illa. Bayan duk wannan, wannan magani yana aiki sosai. Babban abu shine a hankali bin umarnin kwararrun likitocin likita da kuma buƙatun umarnin don amfani daga masana'antar wannan samfur.

Nikolai daga Tomsk: “Na daɗe ina fama da ciwon sukari na type 2 na dogon lokaci. Likita ya ba da allunan Methine. Kuma shekaru da yawa yanzu ina shan su don rage sukari. A cikin kunshin allunan 60 na 1.0 g. Yana da matukar mahimmanci a gare ni cewa metformin (sashi mai aiki) yana hana gluconeogenesis a cikin hanta, yana rage shayewar glucose daga hanji, yana kuma haɓaka amfani da keɓaɓɓun glucose da ƙara haɓakar jijiyoyin jiki zuwa insulin. Magungunan na daidaita yanayin jikina kuma yana rage nauyin jiki. Akwai sakamako masu illa a cikin nau'in tashin zuciya da dandano a cikin bakin, rage cin abinci da zafin ciki, wanda wani lokacin yakan faru. Ina shan kwamfutar hannu sau 2 a rana. "Magungunan na taimaka min sosai, kuma ba na tunanin rayuwa in ban da ta."