Tsarin tsari: umarni da sake dubawa, farashin Allunan

Metformin yana cikin rukunan biguanides, tasirin hypoglycemic wanda ya danganta da raguwar juriya na insulin jigilar nama, da kuma haɓakar haɓakar glucose ta mai da ƙwayoyin tsoka. Magungunan yana hana shan glucose a cikin hanji, ya toshe gluconeogenesis, yana kwantar da hanta a jiki. Hakanan Metformin yana da tasiri mai amfani akan tasoshin jini, yana hana rikicewar jijiyoyin jini a cikin cutar sankara.

Magungunan ba ya ta da ƙwayoyin beta zuwa samar da insulin, saboda haka yana da hadari dangane da haɓakar hypoglycemia.

Bayan gudanarwa, matsakaicin warkewa yana tasowa bayan 2 hours, jimlar lokacin aikin shine 6 hours.

An nuna magungunan don lura da ciwon sukari na 2, musamman kiba mai rikitarwa, in babu abinci da motsa jiki.

Contraindications

• hali na lactic acidosis (tarawa a kyallen takarda na lactic acid)
• ketoacidosis
• nau'in ciwon sukari guda 1
• ciki
• shekarun yara
• cututtukan jini da na cutar kansa
• mai tsanani hanta da koda dysfunctions
• na kullum mai shan giya
• decompensated cututtukan zuciya
• yawan tashin hankali.

Sashi da hanyar gudanarwa

An saita sashi daban-daban, yin la'akari da glycemia da glycosuria.

Maganin farko na allura shine 850 mg / day. A cikin makonni biyu, da sannu a hankali yana ƙaruwa har sai an sami ingantaccen kulawar glycemic. Adadin kulawa - 2 Allunan / rana.

Matsakaicin izinin yau da kullun shine allunan 3.

Za'a raba kashi biyu akan kwamfutar hannu 1 zuwa allurai biyu. Theauki magani a ko bayan abinci. Lokacin ɗauka kafin cin abinci, lokacin da za a sami sakamako mai warkewa yana da tsawo.

Ga marasa lafiya bayan shekaru 60 kuma tare da rikice-rikice na rayuwa mai rauni, ƙara sashi tare da taka tsantsan.

Side effects

• lactic acidosis (tare da mummunan hanta ko ƙone koda, rashin maye a cikin maye, lalata jini na zuciya)
• yawan haila
• Tasirin gastrointestinal: anorexia, zawo, tashin zuciya, dandano na ƙarfe, raunin ciki (ya fito a farkon jiyya ko tare da karuwa mai yawa)
• malabsorption na bitamin B12 da B9
• rashin lafiyan cuta mai narkewa.

An tsara foda don monotherapy ko a hade tare da sulfonylurea ko insulin. Ana gudanar da aikin haɗin gwiwa tare da insulin a cikin asibiti har sai an samar da ingantaccen sashi don hana ci gaban hauhawar jini.

A lokacin warkarwa, ya zama dole don sarrafa matakin serum creatinine sau daya a kowane watanni shida, kuma sau ɗaya a shekara don bincika jini don matakin bitamin B12.

A cikin jiyya tare da tilastawa, barasa ba a da ake so.

Yin amfani da shi a lokaci guda tare da kwayoyi don lura da cututtukan haɗin gwiwa na iya haɓaka ko rage ƙarfin tasirinsa. Saboda haka, kulawa ta lokaci-lokaci na kwayoyi da yawa ya kamata a sarrafa shi ta hanyar halartar likitan likitanci, la'akari da hulɗa da kwayoyi.

Umarnin don amfani da miyagun ƙwayoyi

Tabbas, kusan kowane mai haƙuri koyaushe yana ƙoƙarin yin nazarin umarnin daga masana'anta kafin amfani da magani. Kuma wannan ita ce shawarar da ta dace. Tabbas, a wannan yanayin ne kawai zai yuwu a iya sanin kai tsaye wacce irin illa ce zata iya faruwa saboda rashin kyakkyawan tsarin magani, da kuma yadda yake shafar jikin mutum da menene ingantaccen tasirin amfani daga tsawan lokacin amfani da maganin.

Da farko, ya kamata a lura cewa ana ba da maganin ta hanyar Allunan. Akwai fakitoci waɗanda ke ɗauke da allunan talatin, kuma akwai waɗanda a cikinsu akwai sittin.

Babban tasiri na magunguna wanda Formin Pliva ya bayyana a cikin gaskiyar cewa bayan an tsawaita shi, yana yiwuwa a rage matakin glucose a cikin jinin mai haƙuri. Haka kuma, ana bada shawara a sha shi daidai ga waɗancan marasa lafiya waɗanda ke da 'insulin-ominira, watau, waɗanda basa yin allurar insulin.

Wannan ingantacciyar dukiya mai yiwuwa ne saboda gaskiyar cewa babban abu mai haɓaka yana inganta ingantaccen amfani da glucose. A sakamakon haka, dukkanin hanyoyin gluconeogenesis da ke faruwa a hanta an hana su. Yawan shaye-shayen carbohydrates masu tsabta wadanda suke kasancewa a cikin narkewa na kowane mutum shima yana da matukar raguwa.

Wani ingantaccen fasalin da ke bambanta Tsarin Pliva shine cewa yana ba da gudummawa ga haɓaka ƙimar jijiyoyin ƙwayoyin jikin mutum duka zuwa insulin. Abin da ya sa, zai yiwu a rage matakan glucose a cikin jinin mai haƙuri.

Gaskiya ne, idan zamuyi magana game da yiwuwar kara yawan samar da insulin a cikin jiki saboda tsawaita amfani da maganin, to a wannan yanayin tasirin zai zama marasa mahimmanci.

Amma sananne ne cewa bayan shan Formin, akwai raguwa a cikin adadin triglycerides a cikin jinin mai haƙuri, kazalika da raguwa cikin coagulability na ruwan da aka ambata.

Ana ɗaukar magani a ciki, mafi girman taro na babban aiki a cikin jiki an samu sa'o'i biyu bayan gudanarwa. Amma yawan shansa na jini yana faruwa ne bayan awa shida.

An cire ta daga mai haƙuri ta hanjin kodan.

Yaushe za a fara shan maganin?

An riga an faɗi a sama cewa yana da mahimmanci don fara magani kawai bayan fara shawara tare da likitanka. Ba za ku iya fara magani mai zaman kansa tare da wannan magani ba.

Yawancin lokaci, a cikin irin wannan rukuni na marasa lafiya waɗanda aka ba da shawarar su Formin Pliva, waɗannan marasa lafiya suna kamuwa da cutar sukari ta 2.

Kuma yawanci waɗannan marasa lafiya ne waɗanda ke da alamun matsala da yawan kiba, da waɗanda ba sa ɗaukar insulin ta hanyar allura.

Amma yana da mahimmanci a tuna cewa Formli pliva yana da tarnaƙi mara kyau. An contraindicated a wannan yanayin:

• lokacin da mara lafiya ya kamu da cutar kansa ko mai ciwon sukari,
• Hakanan yana iya yiwuwa yayin da mara lafiyar ke fama da cututtukan cututtuka daban-daban ko tiyata, sakamakon abin da aka sanya shi ta hanyar insulin allurar,
• contraindications ya hada da bayyanannun matsaloli tare da aikin zuciya, da kuma duk sakamakon cututtukan wannan sashin,
• Bai kamata a sha magani ba lokacin daukar ciki ko lokacin da mace take shayarwa,
• kuma ba shakka, lokacin da akwai rashin haƙuri ga mutum wanda aka haɗa shi da magani.

Nazarin marasa lafiya da yawa sun nuna cewa yana da mahimmanci a bi abinci na musamman yayin lura da wannan magani.

Ya kamata ya zama mafi yawan adadin kuzari da kuma ba da gudummawa ga ƙimar nauyi na haƙuri mai dacewa. Hakanan kusan dukkanin kwararrun masana suna da'awar wannan.

Menene analogues da farashin su?

Kamar kowane magani, Formin Pliva yana da nasa analogues. Farashin su ya danganci kamfanin kamfanin kera su, wanda a cikin ƙasa ake yin waɗannan kwayoyi. Idan muna magana ne game da gaskiyar cewa wannan wakilin warkewa ne na duniya, to, farashi, bi da bi, zai kasance sau da yawa fiye da takwaransa na Rasha.

A kowane hali, kafin fara magani don cutar rashin lafiyar, ya kamata koyaushe ka nemi likitanka. Kuna buƙatar ganowa daga gare shi wane sakamako masu illa na iya faruwa daga wani magani, da kuma menene maganin hana haihuwa don amfanin ta. Yana da mahimmanci a bincika cikakke kuma bayan haka fara magani tare da Formin Pliva, umarnin don amfani da maganin ya bayyana a cikin wane yanayi ake amfani da miyagun ƙwayoyi, da kuma a cikin menene magani.

Wasu lokuta a farkon farawa daga tsarin narkewa, wasu rashin jin daɗi na iya faruwa. Wannan yana nuna kanta a cikin tashin zuciya ko amai. Hakanan yana iya yiwuwar raguwar ci ko kuma ɗanɗano mai ban mamaki a bakin.

Wasu marasa lafiya suna ba da rahoton fatar fata tare da ciwon sukari. Tabbas, idan kun sha maganin a cikin allurai masu yawa sosai, to mafi tasirin rashin lafiyar zai iya faruwa.

Idan zamuyi magana game da wane analogues ne mafi mashahuri a yau, to, alal misali, likitoci da yawa zasu iya tsara Bagomet, farashi yana farawa daga 130 kuma ya kai 220 rubles a kowane kunshin, dangane da adadin allunan da ke ciki. Kudin kuma ya shafi yawan babban abu, alal misali, kunshin sittin na sil na 850 MG an kiyasta shi a 220 rubles, amma wannan adadin 1000 allunan magungunan tuni sun riga sun kashe sama da dala ɗari huɗu.

Akwai kuma analog kamar Glycon. Hakanan farashinsa ya dogara da maida hankali kan babban abu da adadin allunan. Ya tashi daga 115 zuwa 280 rubles. Kasar da aka kirkirar wadannan kwayoyin, kamar yadda ta gabata, ita ce kasar Argentina.

Amma ya kasance hakan yana iya, bai kamata ku canza canjin magani wanda likitanku ya bada shawarar ba, in ba haka ba kawai kuna iya cutar da lafiyar ku.

Bidiyo a cikin wannan labarin ya bayyana yadda ake ɗaukar Formin da sauran kwayoyin.

Pharmacokinetics

Bayan gudanarwa, babban abu yana narkewa daga ƙwayar gastrointestinal. Bioavailability zai iya kaiwa kashi 60%. Ana lura da mafi girman yawan plasma bayan sa'o'i 2.

TAFIYA! Kudin shiga tare da abinci yana rage matsakaicin ƙwayar cutar ta hanyar 40%, cikakken tasirin warkewa yana faruwa a minti 35 daga baya.

Yana tarawa cikin sel jini, baya ɗaukar ƙwarin plasma. Ana lura tarin yawa a tsokoki, hanta da ƙodan koda, da kuma a cikin ƙwayoyin hancin salivary.

Cire rabin rayuwar shine 6.5 hours.

Ana amfani dashi don nau'in mellitus na sukari na 2, wanda ke haɓaka da sha'awar yanayin ketoacidotic. Dalilin da aka ba da shawarar maganin shi ne karancin abincin.

Side effects

• gastrointestinal fili: halayen dyspeptik (tashin zuciya, tashin zuciya, ƙwannafi, ciwon ciki), zawo, zazzaɓi, rashin ci,
• Tsarin endocrin: rage matakan glucose,
• metabolism: lactic acidosis, rashi na bitamin B₁₂,
• tsarin jinin haila: megaloblastic type anaemia,
• fata: rashes, itching.

Yawan abin sama da ya kamata

• tashin zuciya
• amai
• zawo
• raguwa a cikin zafin jiki
• ciwon ciki
• myalgia
• saurin numfashi
• tsananin farin ciki
• asarar sani
• ci gaba na rashin daidaituwa.

Farfesa ya hada da:

• rushewa da jami'ai masu rauni,
• asibiti a asibiti,
• maganin hemodialysis
• magani na alamomi.

Hulɗa da ƙwayoyi

Haɓaka sakamako iri iri yana yiwuwa tare da yin amfani da layi ɗaya yin amfani da formin da sauran hanyoyin. Don haka:

• Abubuwan da ke amfani da maganin sulfonylurea (Butamide, Glibenclamide), salicylates (Aspirin, Salicylamide), acarbose, non-steroidal anti-inflammatory (Nimesil, Ketorol), inhibitors na monoaminoxygenase (Selegiline, Nialamide), oxytetracycline azolefin cyclopenneyinyinyinne, (Anaprilin, Concor) haɓaka tasirin rage sukari cikin babban abu,
• glucocorticosteroids (Beclomethasone, Methylprednisolone), maganin hana cin hanci Aminazine), nicotinic acid (Cordiamin, Acipimox) na iya rage tasirin hypoglycemic,
• nifedipine yana haifar da yawan sha, mafi girman abinda ke cikin plasma, yana hana isashshen abu mai aiki,
• cimetidine yana rage jigilar metformin, yana haifar da haɗarin haɗarin lactic acidosis,
• magungunan cationic (Digoxin, Morphine, Vancomycin) tare da tsawaita amfani da shi na iya ƙara yawan abubuwan Metformin a cikin jini da kashi 60%,
• anticoagulants ya raunana ayyukan ƙarshen,
• aidin-dauke da bambanci jami'ai suna ba da gudummawa ga tara babban abun da ke ciki tare da haɓakar lactic acidosis.

Umarni na musamman

A cikin jiyya tare da miyagun ƙwayoyi ya kamata:

• kula da aikin koda
• domin sanin taro na lactate a cikin jini na jini sau biyu a shekara,
• Kula da kulawar glucose idan aka haɗasu da insulin, abubuwan da ake amfani da su na sulfonylurea.

TAFIYA! Ayyukan tiyata mai zurfi, raunin da ya faru, ƙonewa yanki mai yawa, cututtukan da ke haifar da kumburi waɗanda ke faruwa tare da hauhawar zazzabi - duk wannan alama ce don shafewar Kwayar tare da ƙarin alƙawarin insulin.

Yarda da tsufa

Zai yuwu a rubuto wa mutane sama da 65 shekaru a karkashin kulawa ta gaba, la'akari da kimantawar yiwuwar tasirin warkewa da illa mai illa. Ana buƙatar waɗannan marasa lafiya don tantance ƙimar halittarine kafin fara jiyya (ƙimar ƙirar creatinine ba abin dogara bane ga kimanta aikin koda).

Kwatanta tare da analogues

Kwayoyi masu zuwa suna da irin wannan tsari na magunguna:

1. Vipidia. Abubuwan da ke aiki shine alogliptin. Yana shafar aikin insulin a cikin farji, bioavailability ya kai kashi 100%. An hana shi da nau'in 1 mellitus na ciwon sukari. Yi amfani da hankali a gaban ƙwayar ƙwayar ƙwayar cuta, a hade tare da insulin da sulfonylureas. Aikin yau da kullun shine 25 MG. Yarda da kai ba tare da abinci ba, ba tare da taunawa ba, ba tare da shan ruwan sha ba. Ba a gano ma'amala da wasu magunguna ba.
2. Glibenclamide. Babban abu shine glibenclamide. Yana ƙarfafawa na insulin kira ta sel selgerhans. Yana inganta yanayin jijiyar nama zuwa insulin, yana taimakawa rage lipoproteins, yana da tasirin antithrombotic. An sami matsala a cikin narkewar abinci, hanta mai narkewa, hanta ta cire. Yana da kyau a cikin garkuwar jini. An saita kashi akayi daban-daban dangane da tsananin cutar siga da kuma lokacin haƙuri.
3. Miglitol. Yana toshe alfan-glucosidase na enzyme alpha-glucosidase akan epithelium na karamin hanji. Yana hana fashewar polysaccharides zuwa glucose, rage yawan shanshi. Kusan ba a hade da sunadarai na jini ba, ƙwayar koda na faruwa ba a canzawa. An haramta amfani da miyagun ƙwayoyi don amfani da cututtukan ulcerative, kasancewar manyan hernias. Ya kamata a ɗauka tare da shi ko bayan abinci.
4. Avandiya Abubuwan da ke aiki shine rosiglitazone. Yana haɓaka azanci na tsopose nama zuwa insulin, tsokoki ƙashi, hanta hanta. Yana ƙarfafa metabolism, rage taro na glucose, insulin, acid mai kyauta a cikin jini. Yana ɗaukar nauyin garkuwar jini zuwa babban digiri, wanda ba ya dogara da yawan ƙwayoyi da shekarun haƙuri ba. Bakin ciki da kodan. Ana amfani dashi a cikin haɗin gwiwa tare da insulin. Aka kwantar da shi a cikin ciwo na rashin jijiyoyin zuciya, gazawar zuciya. Karɓar farashi ana yin shi ba tare da la'akari da cin abinci ba.
5. Starlix. Babban abu shine ƙirar halitta. Yana taimakawa don dawo da farkon farkon samar da insulin, ƙara matakinsa a cikin mintina 15 na farko bayan cin abinci, sakamakon abin da ke haifar da canji a cikin glucose. Ana nuna haɓakar rabin sa'a kafin abinci sau 3 a rana. Yi amfani tare da taka tsantsan a cikin mummunan tasirin rikicewar hanta da ƙodan. Ana iya amfani dashi azaman monotherapy.

Lyudmila: “Dan uwana ya kamu da cutar sankara yayin 'yan shekaru da suka gabata. Tun daga wannan lokacin, yana ta shan magunguna, ɗayan ɗayan Kwayoyi ne. A baya can, sukari ya kai 18. Saida aka fara jiyya. Shin Formine ya taimaka? Ee, kuma sosai m. Wani dangi yana ɗaukar magungunan daidai kamar yadda aka tsara, baya jin tsoron gano alamun glucose. Kuma ya tsaya lafiya a matakin 5-6. "

Olga: “Kakata tana da ciwon sukari.Na tabbata ba zan taɓa samun wannan ba, tunda nauyi da sukari koyaushe suna cikin kewayon al'ada. Amma a lokacin ciki na biyu, an gano cutar sankarar mahaifa, wanda bayan haihuwa ta koma al'ada. The endocrinologist ya rubuta min Formin. Shahararren magani ne wanda ke taimakawa ci gaba da sukari. ”

Formin wakili ne na antidiabetic, ingancinsa wanda yawancin marasa lafiya ke lura dashi. Ba lallai ba ne don aiwatar da gwamnatinsa mai zaman kanta, tunda akwai contraindications da yawa. Kafin amfani, yakamata ka nemi kwararrun likitoci wanda zasu iya tantance duk kasada da kuma tasirin warkewar cutar.