Rashin halaye mara kyau

abu mai aiki: insulin jikin mutum (rDNA)

1 ml na allura ta ƙunshi IU 100 na insulin biosynthetic ɗan adam (wanda aka samar ta amfani da fasahar rDNA a ciki Sankarinka )

1 vial of mystitis 10 ml, wanda yake daidai da 1000 IU.

1 IU (raka'a ta ƙasa) daidai yake da 0.035 MG na insulin ɗan adam mai rai,

magabata: zinc chloride, glycerin, metacresol, sodium hydroxide, tsarke hydrochloric acid, ruwa don allura.

Kayan magunguna

Rage tasirin sukari shine inganta haɓaka glucose ta kyallen takarda bayan ɗaurin insulin ga masu karɓa da ƙwayoyin mai, da kuma hanawar sakin glucose daga hanta.

Sakamakon binciken asibiti a cikin ɗayan kulawa mai zurfi don magance cututtukan hyperglycemia (matakan glucose jini sama da 10 mmol / L) a cikin marasa lafiya na 204 da marasa lafiya da 1344 ba tare da ciwon sukari waɗanda suka shiga babban tiyata sun nuna cewa normoglycemia (matakin glucose 4, 4- 6.1 mmol / L), wanda gwamnatin Actrapid ® NM ta gabatar, rage mace-mace ta hanyar 42% (8% idan aka kwatanta da 4.6%).

Actrapid ® NM shiri ne na insulin gajere.

Ana lura da farawa a cikin minti 30, ana samun mafi girman tasirin a cikin awanni 1.5-3.5 kuma tsawon lokacin aikin shine kusan awanni 7-8.

Pharmacokinetics Rabin rayuwar insulin daga jini 'yan mintina ne. Saboda haka, yanayin aikin shirin insulin yana faruwa ne kawai don halayen sha. Wannan tsari ya dogara da dalilai da yawa (alal misali, yawan insulin, hanya da wurin allura, kauri daga cikin ƙwanƙwaran ƙwayaji, nau'in ciwon sukari), wanda ke haifar da bambancin mahimmancin sakamakon shirin insulin a cikin ɗayan kuma a cikin daban-daban marasa lafiya.

Baƙon Mafi girman hankali a cikin jini shine an kai shi cikin awa 1.5-2.5 bayan gudanar da maganin.

Rarraba. Babu mahimmancin ɗaure wa insulin zuwa ƙwayoyin plasma, ban da keɓance ƙwayoyin cuta zuwa gare shi (idan akwai), ba a gano shi ba.

Tsarin rayuwa. An cire insulin na mutum ta hanyar kariya ta insulin ko kuma ƙarancin insulin-insulin kuma, ta yiwu, ta hanyar disproide isomerase. An gano wurare da yawa a inda kwayar insulin ta mutum ta gudana. Babu wani daga cikin metabolites da aka kafa bayan hydrolysis wanda ke da aikin nazarin halittu.

Kiwo. Tsawon lokacin rabin rayuwa na insulin an tantance shi da yawan abinda yake samu daga kasusuwa na nama. Abin da ya sa tsawon lokacin rabin rayuwa na ƙarshe (t½) yana nuna ƙarar sha, kuma ba kawarwa (kamar haka) na insulin daga ƙwayar jini (t½ na insulin daga cikin jini kawai 'yan mintuna). Dangane da bincike, t½ awa 2-5.

Yara da matasa. An yi nazarin bayanan kantin magani na Actrapid ® NM a cikin adadi kaɗan (n = 18) na yara (shekaru 6-12) da matasa (13-17 shekara) tare da ciwon sukari. Limitedarancin bayanai suna ba da shawara cewa bayanin furotin na insulin a cikin yara, matasa da manya kusan iri ɗaya ne. Koyaya matakin c _max (mafi yawan maida hankali) ya banbanta da yara na shekaru daban-daban, yana nuna mahimmancin zaɓi ɗaya na allurai na ƙwayoyi.

Bayanan lafiya na farko.

Karatuttukan na farko (mai guba na maimaituwa game da shaye-shayen ƙwayoyi, ƙanƙan ƙwayoyi, ƙwayoyin cuta, tasirin guba kan iyawar haihuwa) bai bayyana haɗarin gudanar da miyagun ƙwayoyi Actrapid ® NM ba.

Ciwon sukari.

Yin hulɗa tare da wasu kwayoyi da sauran nau'ikan ma'amala

Kamar yadda kuka sani, adadin kwayoyi suna shafar metabolism metabolism.

Magunguna waɗanda zasu iya rage buƙatar insulin.

Magungunan hypoglycemic na baka (PSS), monoamine oxidase inhibitors (MAOs), b-blockers, ACE inhibitors (ACE), salicylates, anabolic steroids da sulfonamides.

Magunguna waɗanda zasu iya ƙara buƙatar insulin.

Abubuwan hana hana haihuwa, thiazides, glucocorticoids, hormones thyroid, sympathomimetics, hormone girma da danazole.

• adrenergic blockers na iya rufe alamun hypoglycemia da rage jinkirin dawowa bayan hypoglycemia.

Octreotide / lanreotide na iya ragewa da haɓaka buƙatar insulin.

Barasa na iya haɓaka ko rage tasirin insulin.

Siffofin aikace-aikace

Rashin isasshen dosing ko dakatar da magani (musamman tare da nau'in ciwon sukari na I) na iya haifar da shi hawan jini da ketoacidosis masu ciwon sukari. Yawancin lokaci, alamun farko na hyperglycemia suna haɓaka hankali a kan sa'o'i da yawa ko kwanaki. Sun haɗa da ƙishirwa, yawan urination, tashin zuciya, amai, amai, jan fata da bushewar fata, bushewar baki, rashin ci, da ƙamshin acetone a cikin iska mai ƙuna.

A nau'in ciwon sukari na I, hyperglycemia, wanda ba a kula dashi ba, yana haifar da ketoacidosis mai ciwon sukari, wanda ke da mutuƙar mutuwa.

Hypoglycemia na iya faruwa idan kashi insulin yayi yawa sosai dangane da buƙatar insulin. Game da cutar hypoglycemia ko kuma idan ana zargin hypoglycemia, kada ku bayar da maganin.

Ski abinci ko karin yawan aiki na jiki wanda ba a tsammani ba na iya haifar da hauhawar jini.

Marasa lafiya waɗanda suka inganta mahimmancin matakan glucose na jini saboda ƙwaƙwalwar insulin mai zurfi na iya lura da canje-canje a alamominsu na yau da kullun, abubuwan da ke haifar da ciwon sukari, wanda ya kamata a yi gargaɗi a gaba.

Alamun gargaɗin da aka saba na iya ɓacewa a cikin marasa lafiya da ke fama da ciwon sukari na dogon lokaci.

Abubuwan cuta, musamman cututtuka da zazzabi, suna ƙara buƙatar insulin.

Canza haƙuri ga wani nau'in ko nau'in insulin yana faruwa ƙarƙashin tsayayyen kulawar likita. Canji a cikin maida hankali, nau'in (masana'anta), nau'in, asalin insulin (ɗan adam ko analog na insulin mutum) da / ko hanyar samarwa na iya buƙatar daidaita yanayin insulin. Marasa lafiya waɗanda aka canzawa zuwa Actrapid ® NM tare da nau'in insulin daban-daban na iya buƙatar haɓaka yawan adadin injections na yau da kullun ko canji a sashi idan aka kwatanta da insulin da suke yawanci. Bukatar zaɓin kashi na iya tashi duka a lokacin farkon sabon magani, da kuma a farkon fewan makonni ko watanni na amfani.

Lokacin amfani da kowane magani na insulin, halayen na iya faruwa a wurin allurar, wanda zai iya haɗawa da jin zafi, redness, itching, amya, kumburi, kumburi, da kumburi. Canza wurin allurar a koyaushe a cikin yanki ɗaya na iya rage ko hana waɗannan halayen. Abubuwan da suka shafi yawanci yakan tafi bayan 'yan kwanaki ko makonni. A cikin lokuta mafi sauƙi, halayen a wurin allurar na iya buƙatar dakatar da jiyya tare da Actrapid ® NM.

Kafin tafiya tare da canjin yanki na lokaci, marasa lafiya ya kamata su nemi likita, tunda wannan ya canza jigilar allurar insulin da abinci.

Ba za a iya amfani da NPM cikin pumps na insulin don yin aiki da insulin na tsawon lokaci saboda haɗarin laka a cikin shamburarsu.

Haɗin thiazolidinediones da samfuran insulin.

Lokacin da aka yi amfani da thiazolidinediones a hade tare da insulin, an ba da rahoton maganganun cututtukan zuciya na damuwa, musamman a cikin marasa lafiya da dalilai masu haɗari don lalata zuciya.

Actrapid ® NM ya ƙunshi metacresol, wanda zai haifar da halayen rashin lafiyan.

Tsofaffi marasa lafiya (> 65 shekara).

Ana iya amfani da miyagun ƙwayoyi Actrapid® NM a cikin tsofaffi marasa lafiya.

A cikin marasa lafiya tsofaffi, ya kamata a ƙarfafa kulawar glucose kuma ana daidaita sashin insulin ɗai-ɗai.

Renal da hanta ta gaza

Rashin ƙarfi da ƙarancin hepatic na iya rage buƙatar insulin. A cikin marasa lafiya tare da matsalar koda da hepatic, ya kamata a ƙarfafa saka idanu na glucose kuma ana daidaita yawan insulin ɗai-ɗai.

Ana iya amfani da miyagun ƙwayoyi Actrapid® NM a cikin yara da matasa.

Yi amfani da lokacin daukar ciki ko lactation .

Saboda insulin baya ƙetare shinge na ƙwayar cutar ƙwayar mahaifa, babu iyaka ga maganin masu ciwon sukari tare da insulin yayin daukar ciki. An ba da shawarar ƙarfafa saka idanu kan matakin glucose a cikin jini da kuma lura da lura da kula da mata masu juna biyu da masu ciwon sukari a duk tsawon lokacin da suke cikin ciki, da kuma tare da shakkuwar daukar ciki, tunda rashin saurin kamuwa da cutar sikari yana ƙaruwa da haɗarin rashin lafiyar tayin da mutuwa.

Bukatar insulin yawanci yana raguwa a farkon farkon ciki kuma yana ƙaruwa sosai a cikin watanni na biyu da na uku.

Bayan haihuwa, buƙatar insulin da sauri ya koma tushe.

Hakanan babu wasu hani game da lura da ciwon sukari tare da insulin yayin shayarwa, tun da kulawa da mahaifiyar ba ta haifar da wata haɗari ga jariri.

Nazarin cututtukan dabbobi na dabbobi ta amfani da insulin mutum

bai bayyana wani mummunan sakamako ba game da haihuwa.

Thearfin yin tasiri akan ƙimar amsawa yayin tuki motocin ko wasu hanyoyin.

Amsar mai haƙuri da iyawar sa na iya mai da hankali na iya kasancewa yana illa tare da cututtukan jini. Wannan na iya zama abin haɗari cikin yanayi inda wannan damar ke da mahimmanci musamman (alal misali, lokacin tuki mota ko injina).

Ya kamata a shawarci marasa lafiya su dauki matakan hana hypoglycemia kafin tuki. Wannan yana da mahimmanci musamman ga marasa lafiya waɗanda suka raunana ko raunin alamun bayyanar cututtukan cututtukan jini, ko aukuwa na hypoglycemia suna faruwa akai-akai. A irin waɗannan yanayi, dacewar tuki a general yakamata a auna.

Sashi da gudanarwa

Actrapid ® NM magani ne mai ɗan gajeren lokaci, saboda haka ana yawan amfani dashi a hade tare da insulin aiki na tsawon lokaci.

Sashi na insulin ne mutum kuma likita ya ƙaddara shi bisa ga bukatun mai haƙuri.

Abun da ake buƙata na yau da kullun don insulin yawanci daga 0.3 zuwa 1.0 IU / kg / rana. Bukatar yau da kullun don insulin na iya ƙaruwa a cikin marasa lafiya tare da juriya na insulin (alal misali, a cikin samartaka ko cikin kiba) da raguwa a cikin marasa lafiya tare da sauran insulin na ƙarshe samar da insulin.

Ya kamata a yi allurar 30 mintuna kafin babban ko ƙarin abincin da ya ƙunshi carbohydrates.

Cututtukan haɗin gwiwa, musamman cututtuka da zazzabi, yawanci suna ƙara buƙatar haƙuri ga insulin. Kidneyarancin koda, hanta, ko adrenal, pituitary, ko cututtukan thyroid suna buƙatar canje-canje a cikin sashi na insulin.

Hakanan ana iya buƙatar yin gyaran fuska idan marasa lafiya sun canza ayyukansu na jiki ko abincinsu na al'ada.

Actrapid ® NM an yi shi ne don allurar subcutaneous ko ta cikin ciki.

Actrapid ® NM mafi yawanci ana gudanar da subcutaneously a cikin bangarorin bangon ciki na ciki, har da kwatangwalo, gindi ko kuma ƙwayar tsoka ta kafada.

Ta hanyar allurar subcutaneous zuwa cikin yankin bangon na baya, yawan shan insulin din yana faruwa da sauri fiye da lokacin da aka shigar cikin sauran sassan jiki.

Gabatarwar wani yanki mai fyaɗe fata yana rage haɗarin shiga cikin tsoka.

Bayan allura, allura ya kamata ya kasance a karkashin fata na akalla awanni 6. Wannan zai tabbatar da gabatarwar cikakken kashi.

Don rage haɗarin lipodystrophy, shafin allurar ya kamata koyaushe a canza koda a cikin yanki ɗaya na jiki.

Za'a iya yin allurar cikin ciki a karkashin kulawa na likita.

Ana iya gudanar da gudanar da aiki ta hanyar sarrafa ciki (NMN) a cikin sarrafawa. Dole ne kawai likita ya yi waɗannan allurar.

Ana amfani da Actrapid ® NM a cikin vials tare da sirinji na insulin na musamman waɗanda ke da karatun da ya dace. Actrapid ® NM ya zo tare da kunshin littafin tare da cikakken bayani don amfani.

Aikace-aikacen gudanarwa na ciki.

Tsarin jiko tare da Actrapid ® NM a cikin insulin mutum na 0.05 IU / ml zuwa 1.0 IU / ml a cikin maganin jiko wanda ya ƙunshi 0.9% sodium chloride, 5% ko 10% glucose da 40 mmol / lita potassium chloride kuma yana cikin kwantena na jiko na polypropylene, sun tabbata tsawon awanni 24 a zazzabi a ɗakin. Ko da tare da kwanciyar hankali na dogon lokaci, wani adadin insulin zai iya zama adsorbed a saman ciki na jiko tanki. A lokacin jiko, wajibi ne don saka idanu kan matakan glucose a cikin jini.

Actrapid ® NM ba'a yi amfani da su a cikin famfan insulin ba don tsawan subcutaneous management.

Umarnin don yin amfani da miyagun ƙwayoyi Actrapid ® NM ga mara lafiya.

Kada kayi amfani da Actrapid ® NM:

▶ A cikin kumburin jiko.

▶ Idan mara lafiyar yana da rashin lafiyan (rashin lafiyan hankali) ga insulin ɗan adam ko wani sinadari na Actrapid ® NM,

▶ Idan mai haƙuri ya yi zargin cewa yana yin ɗimin hauhawar jini (ƙananan ƙwayar jini).

▶ Idan ƙarar filastik ɗin ba ta dacewa da lami lafiya ko yana ɓacewa.

Kowane kwalban yana da filayen filastik mai kariya don nuna buɗewa.

Idan akan karɓar vial, ƙafar ɗin ba ta dace da laushi ko ya ɓace ba, ya kamata a komar da vial ɗin zuwa kantin magani.

▶ Idan an adana samfurin ba daidai ba ko an sanyaya.

▶ Idan insulin ba ta bayyana ba mara launi.

Kafin amfani da miyagun ƙwayoyi Actrapid ® NM:

▶ Bincika lambar don tabbatar cewa nau'in insulin kamar yadda aka tsara.

Cire murfin filastik na aminci.

Yadda ake amfani da wannan shiri na insulin.

Ana gudanar da abubuwa na Actrapid ® NM ta allura a karkashin fata (subcutaneously). Koyaushe canza wurin allurar har ma a cikin yankin guda na jikin ka don rage haɗarin bunƙasa hatimin tambura ko alamomin fata a kan fata. Mafi kyawun wurare don allurar kai shine gaban ciki, gindi, gaban cinya ko kafadu. Insulin zai yi sauri idan an saka shi a cikin kugu.

Idan ya cancanta, ana iya aiwatar da Actrapid ra NM a cikin ciki, kawai likita ne zai iya yin waɗannan allurar.

Shigar da Actrapid ® NM, idan ana sarrafa shi shi kadai ko kuma idan aka gauraya shi da insulin aiki na tsawon lokaci.

Tabbatar cewa mara lafiyar yana amfani da sirinji na insulin wanda ya sami kammala karatun da ya dace.

Zana cikin sirinji mai yawan iska daidai yake da yawan insulin da mai haƙuri ke buƙata.

▶ Bi umarnin da likitanku ko likitanku suka ba ku.

Yi allurar insulin insulin. Yi amfani da dabarar allura ta likitanku ko likitan ku.

▶ Rike allura a karkashin fata na akalla aƙalla 6 don tabbatar cewa ana yin cikakken maganin.

Shirye-shiryen insulin na ɗan adam mai inganci suna da inganci kuma masu lafiya amintattu a cikin lura da ciwon sukari na yara daban-daban na yara da matasa.

Bukatar insulin yau da kullun a cikin yara da matasa ya dogara da matakin cutar, nauyin jiki, shekaru, abinci, aiki na jiki, digiri na juriya na insulin da DYNAMICS na matakin glycemia.

Yawan abin sama da ya kamata

Kodayake ba a tsara takamaiman ra'ayi game da yawan ruwan sama don insulin ba, hypoglycemia a cikin nau'ikan matakan nasara na iya haɓakawa bayan gudanarwarsa idan aka yi amfani da allurai masu yawa idan aka kwatanta da bukatun mai haƙuri.

Za'a iya magance cutar sikari da yawa daga ƙwayar abinci ko sukari. Sabili da haka, ana ba da shawarar marasa lafiya da ciwon sukari don ɗaukar samfura da yawa waɗanda ke ɗauke da carbohydrates a koyaushe.

Game da cutar rashin ƙarfi, idan mai haƙuri ya kasance cikin yanayin rashin sani, waɗanda aka horar da su dole ne su jagoranci glucagon subcutaneously ko intramuscularly (daga 0.5 zuwa 1.0 mg).

Bayan mai haƙuri ya isa, yakamata ya ɗauki abincin da ke ɗauke da carbohydrates don hana sake dawowa.

M halayen

Tasirin sakamako na yau da kullun shine maganin cututtukan zuciya. Dangane da nazarin asibiti, kazalika da bayanai game da amfani da miyagun ƙwayoyi bayan fitowar ta a kasuwa, faruwar cutar yawan jini ya bambanta a cikin rukuni na daban daban na marasa lafiya, tare da tsarin magunguna daban-daban da matakan sarrafa glycemic (duba bayani a ƙasa).

A farkon farawar insulin, ana iya lura da kurakurai masu narkewa, edema da halayen a wurin allurar (jin zafi, redness, urticaria, kumburi, kumburi, kumburi da itching a wurin allurar). Wadannan halayen ba da jimawa ba ne. Ingantaccen haɓakawa a cikin kulawar glucose na jini na iya haifar da ingantacciyar yanayin juyayin neuropathy mai raɗaɗi.

Ingantaccen haɓakawa a cikin kulawar glycemic saboda karuwar insulin na iya kasancewa tare da tazara na wucin gadi na maganin ciwon sukari, yayin da ingantaccen tsarin sarrafa glycemic zai iya rage haɗarin ci gaba na cututtukan ciwon sukari.

Dangane da bincike na asibiti, masu biyo baya sune halayen da ba a yarda da su ba wanda aka rarraba shi ta hanyar mita da azuzuwan tsarin sassan jiki a cewar MedDRA.

Dangane da yawan aukuwar lamarin, an rarraba waɗannan halayen zuwa waɗanda ke faruwa sau da yawa (≥1 / 10), sau da yawa (≥1 / 100 zuwa 1/1000 zuwa Adana 1/10000 zuwa MS NMSlide a cikin firiji a zazzabi na 2 ° С -

8 ° C (ba kusa da injin daskarewa ba). Kar a daskare. Ajiye cikin ainihin kayan adon ajiyar daga isar yara.

Ka nisanci zafin rana ko hasken rana kai tsaye.

Kowane kwalban yana da hula mai kariya, filastik mai launi. Idan filayen filastik mai kariya baya dacewa da bakin ciki ko ya ɓace, yakamata a mayar da kwalban zuwa kantin magani.

Kwalabe Actrapid ® NM, wanda ake amfani da su kada a ajiye shi a cikin firiji. Ana iya adanar su na makonni 6 a yanayin zafi har zuwa 30 ° C bayan buɗewa.

Bai kamata a yi amfani da shirye-shiryen insulin da suka daskarewa ba.

Karka taɓa amfani da insulin bayan ranar ƙarewar da aka nuna akan kunshin Zaka iya amfani da bayani mai haske da launi marar launi na Actrapid ® HM.

Rashin daidaituwa

A matsayinka na mai mulkin, ana iya ƙara insulin a cikin magunguna wanda haɗin gwiwar sa ya kasance. Magunguna da aka kara wa insulin na iya haifar da halaka, alal misali, shirye-shiryen da ke ɗauke da abubuwan ɓoye ko ƙwayoyin wuta.

10 ml a cikin kwalba, kwalban 1 a cikin kwali.

Gabatarwar Ka'idoji

Subcutaneous, intramuscular da ciki na jiyya na miyagun ƙwayoyi an yarda. Tare da gudanar da subcutaneous, an shawarci marasa lafiya su zabi yankin cinya don yin allura, a nan ne miyagun ƙwayoyi ke warware hankali a hankali.

Bugu da ƙari, zaku iya amfani da gindi, goshin baya da bango na baya na rami na ciki don injections (lokacin da aka shiga cikin ciki, sakamakon maganin yana farawa da wuri-wuri). Kar a yi allura a cikin yanki daya fiye da sau ɗaya a wata, miyagun ƙwayoyi na iya tsokana lipodystrophy.

Idan ya zama dole don kara insulin gajere tare da tsayi, ana yin algorithm mai zuwa:

1. An shigar da iska cikin duka ampoules (tare da gajeru da tsayi),
2. Na farko, an jawo insulin mai gajeren zango a cikin sirinji, sannan an haɗu da shi tare da wani magani na dogon lokaci,
3. Ana cire iska ta hanyar bugawa.

Masu ciwon sukari da ƙarancin ƙwarewa ba a ba da shawarar gabatar da Actropide zuwa cikin kafada da kansu ba, saboda akwai haɗarin haifar da ƙarancin kiba mai kitse da allura da ƙwayar cutar a ciki. Yana da mahimmanci a lura cewa lokacin amfani da allura har zuwa 4-5 mm, ba a ƙirƙiri ƙoshin kitse mai kwatankwacinsa.

An hana shi shigar da miyagun ƙwayoyi cikin kyallen da aka canza ta hanyar lipodystrophy, har zuwa cikin wuraren hematomas, like, scars da scars.

Ana iya sarrafa abu ta hanyar amfani da sirinji na al'ada, alkalami ko kuma famfon atomatik. A cikin yanayin na ƙarshe, an gabatar da miyagun ƙwayoyi a cikin jikin kansa, a farkon biyun ya cancanci sanin fasahar gudanarwa.

• An sanya allura wanda za'a iya zubar dashi,
• Ana iya hade magungunan cikin sauki, tare da taimakon mai rarraba sassan biyu na miyagun ƙwayoyi, an shigar da su cikin iska,
• Amfani da juyawa, an saita darajar yawan abin da ake so,
• Kitsen kitse ya shafi fata, kamar yadda aka bayyana a tsarin da ya gabata,
• An gabatar da miyagun ƙwayoyi ta hanyar latsa piston a gaba ɗaya,
• Bayan sekan 10, za a cire allura daga fata, an saki fatar.

Dole a jefa allurar dole.

Idan anyi amfani da abu mai motsa jiki na gajere, ba lallai bane a gauraya kafin amfani.

Don ware shaye-shaye marasa inganci na miyagun ƙwayoyi da kuma faruwar cutar, tare da hyperglycemia, bai kamata a saka insulin cikin shiyyoyin da ba su dace ba kuma magungunan da ba a yarda da likita ba ya kamata a yi amfani da su. An hana yin amfani da ƙarewar Actrapid, miyagun ƙwayoyi na iya haifar da yawan insulin.

Gudanarwa ta wucin gadi ko intramuscularly ana aiwatar da shi ne kawai a ƙarƙashin kulawar likitan halartar. An gabatar da Actrapid a cikin jikin rabin sa'a kafin cin abinci, dole ne abinci ya ƙunshi carbohydrates.

Arin haske: ya fi kyau allurar insulin a zazzabi a ɗakin, don haka zafin daga allura zai zama da ƙanƙanin lura.

Ta yaya Actrapid

Insulin Actrapid yana cikin rukuni na kwayoyi waɗanda babban aikin su shine nufin rage matakan sukari na jini. Magani ne na ɗan gajeren lokaci.

Rage sukari saboda:

Matsayi da saurin watsawa ga kwayoyin halittar sun dogara da dalilai da yawa:

1. Sashi na insulin,
2. Hanyar gudanarwa (sirinji, sirinji, sikalin insulin),
3. Wurin da aka zaɓa don gudanar da maganin miyagun ƙwayoyi (ciki, goshin hannu, cinya ko buttock).

Tare da subcutaneous management of Actrapid, miyagun ƙwayoyi ya fara aiki bayan mintuna 30, ya isa yalwataccen taro a cikin jiki bayan sa'o'i 1-3, dangane da halayen mutum na haƙuri, kuma tasirin hypoglycemic yana aiki na awanni 8.

Side effects

Lokacin canzawa zuwa Actrapid a cikin marasa lafiya na kwanaki da yawa (ko makonni, dangane da ɗabi'ar mutum mai haƙuri), ana iya lura da kumburi da matsaloli tare da bayyananniyar hangen nesa.

Sauran m halayen ana rubuta su da:

Sakamakon sakamako na yau da kullun shine hypoglycemia. Idan mara lafiya yana da launin fatar jiki, haushi da wuce gona da iri da jin yunwar, rikicewa, rawar jiki da karuwar gumi, ana iya ganin sukari na jini a kasa da matakin halas.

A farkon alamun bayyanar cututtuka, wajibi ne don auna sukari da cin abinci mai narkewa mai sauƙin narkewa, idan aka rasa nauyi, glucose yana allurar intramuscularly ga mai haƙuri.

A cikin manyan maganganun, hypoglycemia na iya juyawa cikin zama da mace-mace.

A wasu halayen, insulin na insulin na iya haifar da rashin lafiyan da ke faruwa:

Idan mai haƙuri ba ya bi ka'idodin allura a wurare daban-daban, lipodystrophy yana haɓaka cikin kyallen.
Marasa lafiya waɗanda aka lura da cutar basir a ci gaba, ya zama dole a nemi likitanka don daidaita allurai da ake sarrafawa.

Umarni na musamman

Tare da ci gaba da lura da ciwon sukari tare da Actrapid, yana da matukar muhimmanci a kiyaye rikodin matakan sukari na jini ta amfani da glucometer. Gudanar da kai zai hana tsalle tsalle cikin matakan sukari.

Sau da yawa, ana iya haifar da hypoglycemia ba kawai ta hanyar yawan shan magunguna ba, har ma da wasu dalilai:

A yayin da mai haƙuri ya gabatar da isasshen adadin ƙwayoyi ko kuma ya tsallake gabatarwar, yana haɓaka haɓakar hyperglycemia (ketoacidosis), yanayin da ba shi da haɗari, zai iya haifar da tari.

Yi amfani yayin daukar ciki

An ba da damar motsa jiki na motsa jiki idan akwai yiwuwar daukar ciki na mai haƙuri. Duk tsawon lokacin, ya zama dole don sarrafa matakin sukari da canza sashi. Don haka, a cikin lokacin farko na farko, buƙatar maganin ya ragu, a lokacin na biyu da na uku - akasin haka, yana ƙaruwa.

Bayan haihuwar jarirai, an sake buƙatar bukatar insulin zuwa matakin da ya kasance kafin yin juna biyu.

Yayin shayarwa, rage yawan sashi na iya zama dole. Mai haƙuri yana buƙatar kulawa da hankali sosai a kan matakin sukari na jini don kada ya ɓaci lokacin da buƙatar maganin ta kwantar da hankali.

Sayi da adanawa

Kuna iya siyan Actrapid a cikin kantin magani gwargwadon rubutaccen likitanka.

Zai fi dacewa don adana maganin a cikin firiji a zazzabi na 2 zuwa 7 Celsius. Kada kabar izinin samfurin ga zafin kai tsaye ko hasken rana. Lokacin daskararre, Actrapid ya rasa halayensa na rage sukari.

Kafin allurar, mai haƙuri ya kamata ya duba ranar karewar miyagun ƙwayoyi, ba a yarda da amfani da insulin da aka ƙare ba. Tabbatar bincika ampoule ko tafin hannu tare da Actrapid don laka da baƙin inclusions.

Ana amfani da Actrapid daga marasa lafiya da duka nau'in 1 da nau'in ciwon sukari na 2 na mellitus . Tare da amfani da kuma dacewa da abubuwan da likitan ya nuna, hakan ba ya haifar da ci gaban sakamako a jikin mutum.

Ka tuna cewa yakamata a kula da ciwon sukari gabaɗaya: ban da injections na yau da kullun na miyagun ƙwayoyi, dole ne a manne da wani abinci, ka kula da aikin jiki kuma kada a fallasa jiki ga yanayin damuwa.

Kula da ciwon sukari tsari ne mai tsawo kuma mai daukar nauyi. Wannan cutar tana da haɗari tare da rikitarwa, ƙari, mai haƙuri na iya mutuwa idan bai karɓi tallafin magungunan da ake buƙata ba.

Babban bayani game da miyagun ƙwayoyi

An ba da shawarar Actrapid don yaƙi da ciwon sukari. Sunan kasa da kasa (MHH) yana narkewa.

Wannan sanannen sananniyar ƙwayar cuta ce tare da taƙaitaccen sakamako. Ana samunsa ta hanyar maganin da ake amfani da allura. Matsakaicin yanayin miyagun ƙwayoyi shine ruwa mai launi mara launi. Cancantar maganin shine ya bayyana ta hanyar bayyanarta.

Ana amfani da miyagun ƙwayoyi a cikin lura da nau'in 1 da nau'in ciwon sukari na 2. Hakanan yana da tasiri a cikin hyperglycemia, saboda haka ana yin amfani dashi sau da yawa don ba da kulawa ta gaggawa ga marasa lafiya yayin tashin hankali.

Marasa lafiya da ke fama da ciwon sukari da ke dogara da insulin na bukatar sarrafa sukarin jininsu a duk rayuwarsu. Wannan yana buƙatar allurar insulin. Don inganta sakamakon maganin, kwararru suna haɗuwa da nau'ikan ƙwayar cuta bisa ga halaye na mai haƙuri da hoton asibiti na cutar.

Aikin magunguna

Insulin Actrapid HM magani ne mai gajeriyar magana. Saboda tasirin sa, an rage matakan sukari na jini. Wannan mai yiwuwa ne saboda kunna jirgin jigilar kwayar cutar ciki.

A lokaci guda, magani yana rage yawan samar da glucose ta hanta, wanda shima yana ba da gudummawa ga daidaituwar matakan sukari.

Magungunan yana farawa bayan kusan rabin sa'a bayan allura kuma yana kula da tasirinsa har tsawon awanni 8. Ana lura da mafi girman sakamakon a cikin tsakanin awa 1.5-3.5 bayan allura.

Saki siffofin da abun da ke ciki

A kan sayarwa akwai Actrapid a cikin nau'i na mafita don allura. Sauran nau'ikan saki ba su wanzu. Abunda yake aiki shine insulin mai narkewa a cikin adadin 3.5 mg.

Baya ga shi, abun da ke tattare da miyagun ƙwayoyi ya ƙunshi irin waɗannan kayan haɗin tare da kaddarorin taimako kamar:

• glycerin - 16 MG,
• zinc chloride - 7 mcg,
• sodium hydroxide - 2.6 mg - ko hydrochloric acid - 1.7 mg - (suna da mahimmanci don tsara pH),
• metacresol - 3 MG,
• ruwa - 1 ml.

Magungunan ruwa bayyananne ne, mara launi. Akwai shi a cikin kwantena na gilashi (girma 10 ml). Kunshin ya ƙunshi kwalban 1.

Alamu don amfani

An tsara wannan maganin don sarrafa sukarin jini.

Dole ne a yi amfani dashi don cututtuka da rikice-rikice masu zuwa:

• nau'in ciwon sukari guda 1
• nau'in ciwon sukari na 2 wanda ya kasance cikakke ko rashin kulawa da damuwa ga wakilai na hypoglycemic don gudanar da maganin baka,
• cututtukan cututtukan mahaifa, wanda ya bayyana a lokacin haihuwar yaro (idan babu wani sakamako daga ilimin abinci),
• mai ciwon sukari ketoacidosis,
• babban zazzabi da cutar cututtuka a cikin marasa lafiya da ciwon sukari,
• mai zuwa tiyata ko haihuwa.

An haramta shan magani tare da Actrapid, wannan likita ya kamata ya wajabta wannan magani bayan nazarin hoton cutar.

Sashi da gudanarwa

Umarnin yin amfani da miyagun ƙwayoyi ya zama dole don magani ya zama mai tasiri, kuma magani ba ya cutar da mai haƙuri. Kafin amfani da Actrapid, ya kamata ka bincika shi a hankali, kazalika da shawarar kwararrun masana.

Ana gudanar da maganin ne a cikin jijiya ko a keɓe. Dole ne likitan likita ya zaɓi kashi ɗaya na yau da kullun ga kowane mara lafiya. A matsakaici, shine 0.3-1 IU / kg (1 IU shine 0.035 mg na insulin anhydrous). A wasu nau'ikan marasa lafiya, ana iya karuwa ko rage shi.

Ya kamata a gudanar da miyagun ƙwayoyi kimanin rabin sa'a kafin cin abinci, wanda dole ne ya ƙunshi carbohydrates. Yana da kyau a yi allura a cikin bangon ciki na ciki - saboda haka sha yana da sauri. Amma an ba shi izinin sarrafa maganin a cinya da gwiwar gwiwa ko a cikin ƙwayar tsoka mai rauni. Don kauce wa lipodystrophy, kuna buƙatar canza wurin allurar (tsayawa cikin yankin da aka ba da shawarar). Don aiwatar da maganin sosai, allurar ya kamata a kiyaye ta a cikin fata don aƙalla 6 seconds.

Akwai kuma amfani da maganin taurara ta Actrapid, amma gwani yakamata ya bada maganin ta wannan hanyar.

Idan mai haƙuri yana da cututtukan da ke tattare da cuta, to dole ne a canza sashi. Sakamakon cututtukan cututtukan da ke tattare da alamun bayyanar febrile, buƙatar haƙuri ga insulin yana ƙaruwa.

Umarni akan bidiyo na gudanarwar insulin:

Hakanan kuna buƙatar zaɓar matakin da ya dace don karkacewa kamar:

• cutar koda
• rikicewar ƙwayar cuta ta adrenal,
• ilimin hanta na hanta
• cututtukan thyroid.

Canje-canje a cikin abinci ko matakin motsa jiki na mai haƙuri na iya shafar buƙatar jikin mutum na insulin, saboda wanda zai zama dole don daidaita adadin da aka tsara.

Musamman marasa lafiya

Ba a hana yin jiyya tare da Actrapid a lokacin haihuwa ba. Insulin baya wuce cikin mahaifa kuma baya cutar tayin.

Amma dangane da uwaye masu fata, ya zama dole a hankali a zabi sashin, tunda idan ba a kula da su sosai ba, to akwai haɗarin haɓakar haɓaka ko ciwan jini.

Duk waɗannan rikice-rikice na iya shafar lafiyar ɗan da ba a haife su ba, kuma wani lokacin suna tsokani ɓarna. Don haka, yakamata likitoci su lura da matakin sukari a cikin mata masu juna biyu har zuwa haihuwa.

Ga jarirai, wannan magani bashi da haɗari, saboda haka an yarda da amfani dashi yayin shayarwa.Amma a lokaci guda, kuna buƙatar kula da tsarin abincin mace mai shayarwa kuma zaɓi sashi da ya dace.

Ba a ba da maganin ta Actrapid ga yara da matasa ba, kodayake binciken bai sami wani haɗari ga lafiyar su ba. A akasari, ana ba da izinin kula da masu ciwon sukari tare da wannan magani a cikin wannan rukunin na zamani, amma ya kamata a zaɓi sashi daban-daban.

Contraindications da sakamako masu illa

Actrapid yana da ƙananan contraindications. Waɗannan sun haɗa da rashin hankali ga abubuwan da ke tattare da miyagun ƙwayoyi da kasancewar cututtukan jini.

Yiwuwar tasirin sakamako tare da ingantaccen amfani da miyagun ƙwayoyi yana da ƙasa. Mafi yawan lokuta, cututtukan hypoglycemia na faruwa, wanda shine sakamakon zaɓin kashi wanda bai dace da mai haƙuri ba.

Yana tare da waɗannan abubuwan mamaki:

A cikin mawuyacin hali, cututtukan hypoglycemia na iya haifar da fitsari ko riƙewa. Wasu marasa lafiya na iya mutuwa saboda hakan.

Sauran sakamakon sakamako na Actrapid sun hada da:

Waɗannan fasalulluka ba su da halayyar farkon matakin magani. Idan an lura da su na dogon lokaci, kuma ƙaruwarsu ke ƙaruwa, ya zama dole a nemi shawara tare da likitanka game da cancantar irin wannan ilimin.

Yin hulɗa tare da wasu magunguna

Dole ne a haɗu da Actrapid daidai tare da wasu magunguna, ba da wasu nau'ikan magunguna da wasu abubuwa na iya haɓaka ko raunana buƙatun jiki na insulin ba. Hakanan akwai magunguna waɗanda amfani da su suna lalata aikin Actrapid.

Tsarin hulɗa tare da wasu kwayoyi:

Lokacin amfani da beta-blockers, yana da wahala a gano cutar rashin ƙarfi, tunda waɗannan kwayoyi suna lalata alamun ta.

Lokacin da mara lafiya ya sha giya, buƙatar jikinsa ga insulin zai iya ƙaruwa da ragewa. Saboda haka, yana da bu mai kyau ga masu ciwon sukari su daina shan giya.

Magunguna tare da irin wannan sakamako

Samfurin yana da analogues wanda za'a iya amfani dashi idan babu ikon aiwatar da Actrapid.

Manyan sune:

• Gensulin P,
• Bari mu yi yawo P,
• Monoinsulin CR,
• Biosulin R.

Sharuɗɗan da yanayin ajiya, farashi

Ya kamata a kiyaye kayan aikin ba tare da isar yara ba. Don adana kaddarorin miyagun ƙwayoyi, ya wajaba don kare shi daga fuskantar hasken rana. Matsakaicin yanayin ajiya shine digiri 2-8. Sabili da haka, ana iya adana Actrapid a cikin firiji, amma bai kamata a sanya shi a cikin injin daskarewa ba. Bayan daskarewa, maganin zai zama mara amfani. Rayuwar shelf shine shekaru 2.5.

Bayan buɗe kwalbar a cikin firiji kada a sanya shi, domin ajiyar sa na buƙatar zazzabi kimanin digiri 25. Dole ne a kiyaye ta daga haskoki na rana. Rayuwar rayuwar shiryayye na budewa na miyagun ƙwayoyi shine makonni 6.

Kimanin farashin magungunan Actrapid shine 450 rubles. Insulin Actrapid HM Pfereill ya fi tsada (kimanin 950 rubles). Farashi na iya bambanta ta yanki da nau'in kantin magani.

Actrapid bai dace da shan maganin kansa ba, sabili da haka, zaku iya siye magani kawai ta takardar sayen magani.

NOVO NORDISK NOVO NORDISK + FEREIN Novo Nordisk A / C

Yanayi na musamman

• insulin mai narkewa (injiniyan ɗan adam) 100 IU * Wadanda suka kware: zinc chloride, glycerol, metacresol, hydrochloric acid da / ko sodium hydroxide (don kula da pH), ruwa d / da. * 1 IU ya dace da 35 μg na insulin ɗan adam mai narkewa (injiniyan ɗan adam) 100 IU * Fitattun abubuwa: zinc chloride, glycerol, metacresol, hydrochloric acid da / ko sodium hydroxide (don kula da pH), ruwa d / da.

Alamomin nm na aiki

• insulin-insulin-based diabetes mellitus (nau'in I), - wanda ba shi da insulin-da ke fama da cutar sankara na mellitus (nau'in II): mataki na juriya ga wakilai na bakin jini, juriya ga wadannan kwayoyi (yayin hada-hadar magani), tare da cututtukan da ke addabar ciki, aiki, da ciki.

Tasirin nm sakamako masu illa

• Abubuwan da ba a sani ba sun lura a cikin marasa lafiya yayin aikin jiyya tare da Actrapid NM sun fi dacewa da kashi-kashi kuma sun kasance saboda aikin maganin insulin. Kamar yadda yake tare da sauran shirye-shiryen insulin, tasirin sakamako mafi yawancin shine hypoglycemia. Yana haɓakawa a cikin yanayi inda adadin insulin ya zarce buƙatarta. A lokacin gwaji na asibiti, kazalika da lokacin amfani da miyagun ƙwayoyi bayan fitarwarsa a kasuwar mabukaci, an gano cewa yawan hypoglycemia ya bambanta a cikin al'ummomin haƙuri daban-daban kuma lokacin amfani da tsarin magunguna daban-daban, don haka ba zai yiwu ba a nuna ainihin ƙimar ƙimar. A cikin tsananin rauni, asarar hankali da / ko raɗaɗi na iya faruwa, rashi na ɗan lokaci ko na dindindin na aikin kwakwalwa, har ma da mutuwa, na iya faruwa. Nazarin asibiti ya nuna cewa abin da ke faruwa a cikin jini bai bambanta tsakanin marasa lafiya da ke karɓar insulin na mutum da kuma marasa lafiya da ke karɓar insulin. Followinga'idodi masu zuwa ne na yawan tasirin halayen da aka gano yayin gwaji na asibiti, waɗanda aka ɗauke su da alaƙa da amfani da miyagun ƙwayoyi Actrapid NM. An ƙaddara mitar kamar haka: akai-akai (> 1/1000,

Yanayin ajiya

• ci gaba a cikin busassun wuri
• Adana cikin sanyi (t 2 - 5)
• nisantar da yara
• store a cikin duhu wuri

• Brinsulrapi MK, Brinsulrapi Ch, Insulin Actrapid, Levulin

Sunan Latin: Mai aiwatarwa
Lambar ATX: A10AB01
Aiki mai aiki: insulin mai narkewa
Mai masana'anta: Novo Nordisk, Denmark
Hutun hutu daga kantin magani: Da takardar sayan magani
Yanayin ajiya: 2-8 digiri zafi
Ranar cikawa: Shekaru 2.5 - kwalban da aka rufe
bude - wata daya da rabi.

Actrapid shine insulin gajeriyar aiki wanda ake amfani dashi a cikin masu ciwon suga yayin raunin hormonal.

Insulin Actrapid nm ya dace don amfani dashi don kula da marasa lafiya da masu ciwon sukari mellitus. Ana iya amfani da shi duka a gaban kamuwa da cutar insulin-wacce ba ta iya tsayayya da cutar. An nuna shi ta hanyar warkewa mai sauri, lokacin da mai haƙuri ya buƙaci sanya madaidaicin glycemic ɗinsa da sauri.

Abun ciki da nau'i na saki

Abubuwan da ke aiki a cikin abun da ke ciki shine insulin ɗan adam a cikin narkar da tsari. Wadanda suka ƙware a cikin abun da ke ciki: zinc chloride, glycerol, ruwa injection, metacresol, sodium hydroxide.

Ana siyar da miyagun ƙwayoyi ta fom ɗin allura, akwai kuma nau'in wasan kwaikwayo na nm penfill, kuma ana sayar da shi azaman mafita don injections na subcutaneous.

Hanyoyin warkarwa

Magungunan yana da sakamako mai warkewa mai sauri, tunda ya kasance cikin rukunin magunguna na insulins masu saurin aiki. An yi samfurin ne ta amfani da fasaha na bioengineering na DNA wanda aka sake haɗa shi tare da gabatar da al'adun mai yisti. Bayan sarrafa kai tsaye na miyagun ƙwayoyi a ƙarƙashin, abu mai aiki ya fara hulɗa tare da masu karɓar cytoplasmic a cikin membrane na sel. Kayan yana kunna tafiyar matakai a cikin tantanin ta hanyar karfafa biosynthesis na cAMP, wanda ya ba shi damar shiga zurfin shiga cikin tantanin halitta.

Kamar yadda bayanin radar ya nuna, raguwa a cikin sukari jini yana faruwa ne ta hanyar karuwar motsi na ciki da kuma ɗaukar kwayar halittar jikin mutum, wanda ke hanzarta adana kitse a cikin jiki, abubuwan da ke tattare da tsarin furotin, glycogenogenesis yana faruwa, haka kuma raguwa ga samar da glucose ta hanta. Magungunan yana fara aiki a cikin jiki rabin sa'a bayan amfani. Ana samun tasirin gangar jiki bayan sa'o'i 2.5, kuma jimlar adadin bayyanar shine kimanin awanni 7-8.

Hulɗa da miyagun ƙwayoyi

Abubuwan da ke haɓaka tasiri don rage sukari: magungunan maganganu na rashin ƙarfi, magungunan anabolic steroid, androgens, ketoconazole, tetracycline, bitamin B6, bromocriptine, mebendazole, theophylline, masu hana beta-blockers, abubuwan shan giya, wanda ba kawai inganta tasirin bane, amma kuma tsawanta tsawon lokacin aiki.

Matakan sukari na jini yana ƙaruwa: rigakafin mata na baki (analogues na progesterone da estradiol), hormones na thyroid, anticoagulants, clonidine, diazoxide, danazole, maganin tricyclic antidepressants, allunan tashar alli, magungunan opioid, nicotinic acid da nicoteroids, Reserpine, salicylates, octreotide, lanreotide yana tasiri tasirin insulin gaba. Wadannan abubuwan zasu iya rage duka biyu tare da haɓaka da buƙatar magunguna.

Ioarin jini da sulfites suna ba da gudummawa ga lalata ko lalata lalata maganin, kuma beta-blockers suna haifar da alamun karya na hypoglycemia.

Side effects da yawan abin sama da ya kamata

Wani lokaci akwai wasu halayen rashin lafiyan jiki a cikin nau'i na fatar fata ko kumburi, ƙasa da sau da yawa akwai lalata tsotse nama a wuraren allurar. Ko da mafi wuya, abin da ya faru na jurewa (rashin yarda) na insulin mai narkewa.

Game da yawan abin sama da ya wuce, irin wannan yanayin rashin gamsuwa mai yiwuwa ne: asarar bacci na al'ada, bushewar fata, paresthesia, tashin hankali na psychomotor, yawan ci, hanji, bugun jini, ciwon kai, ciwon kai, hanji da baki, tachycardia. Tare da karfin yawan zubar da ruwa, mummunan rashin karfin jini na mashigar matakin yana faruwa kuma mai haƙuri ya faɗi cikin rashin lafiya.

Idan akwai bayyanannun bayyananniyar hypoglycemia, to ya isa a yi amfani da carbohydrates mai sauri (sukari, sandunan cakulan, allunan glucose). Tare da matsin matsakaici, ana gudanar da glucose a cikin jijiya ta hanyar amai. A cikin mummunan hali, ana kiran ƙungiyar motar asibiti kuma ana allurar glucagon, kuma ana buƙatar saka ido a asibiti har sai yanayin ya daidaita.

Lilly Faransa, Faransa

Matsakaicin farashin a Rasha - 1720 rubles a kowace kunshin.

Abubuwan da ke aiki da humalogue shine insulin lispro. Wannan shi ne ɗayan analogues na actrapide a farashi mai tsada. Humalog yana da tasirin gaske cikin sauri, tasirin warkewa yana fara bayyana tsakanin mintuna 15 bayan allura, amma tsawon lokacin aikin shima gajere ne, yana fitowa ne daga awanni 2 zuwa 5 a jere.

Sanofi Avensis Deutschland, Jamus

Matsakaicin farashin a Rasha - 2060 rubles a kowace kunshin.

Apidra ya ƙunshi insulin a cikin nau'i na gluzilin, wanda, kamar analog na waje na baya, yana ba shi damar yin abubuwa da yawa da sauri, amma tsawon lokacin tasirin ba shi da tsawo - a yan awanni kawai.

• Tasiri mai sauri
• Yana taimaka sosai.

Kulawa da marasa lafiya da nau'in ciwon sukari na 1 ana yin su a cikin hanyar maye gurbin insulin. Tare da ƙuntatawa na abinci, gudanarwar insulin na iya hana irin waɗannan masu haƙuri daga haɓaka mummunar rikice-rikice na ciwon sukari.

Lokacin da ake rubuta insulin, ya zama dole ayi ƙoƙarin haifuwa kusa-da-zuwa ƙurar yanayin shigar ta cikin jini. A saboda wannan, nau'ikan insulin guda biyu sune mafi yawan lokuta ana tsara su ga marasa lafiya - tsayi da gajere.

Tsawon lokaci insulins mimic basal (na dindindin qarin) mugunya. An tsara gajeren insulins don ɗaukar carbohydrates daga abinci. Ana gudanar dasu kafin abinci a kashi daya wanda yayi daidai da adadin gurasar burodi a samfuran. Actrapid NM nasa ne ga irin waɗannan insulins.

Hanyar aiwatar da Actrapid NM

Samfurin ya ƙunshi insulin ɗan adam wanda aka samu ta injiniyan kwayoyin. Don samarwarsa, ana amfani da DNA daga yisti na saccharomycetes.

Insulin yana ɗaure wa masu karɓa akan sel kuma wannan hadadden yana samar da kwararar glucose daga jini zuwa cikin tantanin.

Bugu da ƙari, insulin na insrail yana nuna irin waɗannan ayyuka akan tafiyar matakai na rayuwa:

1. Yana haɓaka samuwar glycogen a cikin hanta da ƙashin tsoka
2. Yana ƙarfafa amfani da glucose ta ƙwayoyin tsoka da ƙwayoyin adipose don makamashi
3. Rushewar glycogen an rage shi, kamar yadda ake samu sabbin kwayoyin kwayoyi a cikin hanta.
4. Yana haɓaka kitse mai kitse kuma yana rage ƙiba
5. A cikin jini, ƙwayar lipoproteins tana ƙaruwa
6. Insulin yana haɓaka haɓakar sel da rarrabuwa
7. Yana haɓaka aikin furotin da rage rushewarta.

Tsawon lokacin aikin Actrapid NM ya dogara da kashi, wurin allura da nau'in ciwon sukari. Magungunan yana nuna kaddarorinsa rabin sa'a bayan gudanarwa, an lura da iyakar sa bayan awa 1.5 - 3.5. Bayan 7 - 8 hours, miyagun ƙwayoyi sun daina aikinta kuma enzymes sun lalata shi.

Babban mahimmancin amfani da insulin na Actrapid shine rage matakan glucose a cikin ciwon sukari mellitus duka don amfani na yau da kullun da kuma ci gaban yanayin gaggawa.

Aiki yayin daukar ciki

Ana iya tsara insulin Actrapid NM don rage yawan hyperglycemia a cikin mata masu juna biyu, tunda ba ƙetare shingen jini ba. Rashin biyan diyya ga masu cutar siga a cikin mata masu juna biyu na iya zama haɗari ga jariri.

Zaɓin allurai ga mata masu juna biyu yana da matukar muhimmanci, tunda duka matakan girma da ƙananan na sukari suna lalata tsarin halittar jiki kuma yana haifar da lalata, haka kuma yana kara haɗarin mutuwar tayi.

Farawa daga matakin shirin daukar ciki, likitan endocrinologist ya kamata ya kula da marasa lafiya da masu ciwon sukari, kuma ana nuna su ta hanyar inganta matakan glucose na matakan jini. Bukatar insulin na iya raguwa a farkon farkon lokacin ciki kuma ya karu a na biyu da na uku.

Bayan haihuwa, matakin glycemia yawanci yakan koma zuwa ga siffofin da suka gabata kafin haihuwar.

Ga mata masu shayarwa, gwamnatin Actrapid NM kuma ba ta cikin haɗari.

Amma ba da karuwar buƙatar abinci mai gina jiki, abincin ya kamata ya canza, ya kuma inganta adadin insulin.

Abun ciki da nau'i na saki

Magani don allura - 1 ml:

• abubuwa masu aiki: insulin narkewar ƙwayar ɗan adam - 100 IU (3.5 mg), 1 IU yayi daidai da 0.035 mg na ɗan adam insulin,
• tsofaffi: zinc chloride, glycerin (glycerol), metacresol, sodium hydroxide da / ko hydrochloric acid (don daidaita pH), ruwa don allura.

10 ml a cikin gilashin gilashi, an rufe hatimin tare da marubutan roba da filastik filastik, a cikin fakitin kwali 1 kwalban.

Maganin maganin allura abu ne mara kyau, mara launi.

Short-aiki insulin mutum.

Jinin insulin na jikin dan adam. Yana da insulin na matsakaiciyar lokacin aiki. Yana daidaita metabolism, yana da tasirin anabolic. A cikin ƙwayar tsoka da sauran kyallen takarda (ban da kwakwalwa), insulin yana haɓaka jigilar ƙwayar glucose da amino acid, da haɓakar anabolism na furotin. Insulin yana inganta canzawar glucose zuwa cikin glycogen a cikin hanta, yana hana gluconeogenesis kuma yana ƙarfafa juyar da yawan glucose mai yawa zuwa mai.

Amfani da ciki yayin haihuwa da yara

A lokacin daukar ciki, yana da mahimmanci musamman don kula da kyakkyawan iko na glycemic a cikin marasa lafiya da ciwon sukari. A lokacin daukar ciki, yawan bukatar insulin yakan rage a cikin farkon farkon yana kara girma cikin na biyu da na uku.

An shawarci masu ciwon sukari su sanar da likitan su game da farawa ko shirin daukar ciki.

A cikin marasa lafiya da ciwon sukari mellitus yayin shayarwa (shayarwa), ana iya buƙatar daidaita sashin insulin, abincin, ko duka biyun.

A cikin nazarin kwayoyin cutar guba a cikin in vitro da kuma a cikin jerin vivo, insulin ɗan adam bai sami tasirin mutagenic ba.

Tsarin saki, abun da aka shirya da marufi

Maganin maganin allura abu ne mara kyau, mara launi.

Mahalarta: zinc chloride, glycerol, metacresol, hydrochloric acid da / ko sodium hydroxide (don kula da matakin pH), ruwa d / da.

* 1 IU yayi daidai da μg na 35 na insulin na mutum.

10 ml - gilashin gilashi (1) - fakitoci na kwali.

Sashi Actrapid nm

P / c, cikin / in. An zaɓi kashi na miyagun ƙwayoyi daban-daban yin la'akari da bukatun mai haƙuri. Yawanci, buƙatar haƙuri ga insulin daga 0.3 zuwa 1 IU / kg / rana. Abunda ake buƙata na yau da kullun don insulin na iya zama mafi girma a cikin marasa lafiya tare da juriya na insulin (alal misali, yayin balaga, har ma a cikin marasa lafiya tare da kiba) da ƙananan a cikin marasa lafiya tare da ragowar ƙwayar insulin. Idan masu haƙuri tare da ciwon sukari sun sami daidaitaccen iko na glycemic, to, rikicewar cututtukan sukari yawanci yakan faru ne daga baya. A wannan batun, yakamata mutum yayi ƙoƙari don inganta sarrafa metabolism, musamman, ta hanyar sa ido sosai a kan matakin glucose a cikin jini.

Actrapid ® NM insulin aiki ne gajere kuma za'a iya amfani dashi hade da insulins masu aiki da dadewa.

Ana gudanar da maganin a cikin mintina 30 kafin cin abinci ko abun ciye-ciye wanda ya ƙunshi carbohydrates. Actrapid ® NM yawanci ana kulawa da sc zuwa yankin bangon ciki na ciki. Idan wannan ya dace, to ana iya yin allura zuwa cinya, yankin gluteal ko kuma yanki na ƙyallen ƙashin gwiwa. Tare da shigar da miyagun ƙwayoyi a cikin yankin bangon ciki na ciki, ana samun saurin ɗaukar sauri fiye da gabatarwar zuwa wasu yankuna. Yin aiwatar da allura a cikin fatar fata yana rage haɗarin shiga cikin tsoka.

Wajibi ne a canza wurin allurar a cikin yankin na jiki don hana ci gaban lipodystrophy.

Hakanan zai yiwu, amma likita ne ya ba da umarnin kawai.

Actrapid ® NM kuma ana iya shiga / shiga, kuma kwararrun likitocin ne kaɗai za su iya yin wannan.

Tare da lalacewar kodan ko hanta, an rage buƙatar insulin.

Canjin haƙuri ga wani nau'in insulin ko zuwa shiri insulin tare da sunan kasuwanci na daban yakamata ya faru a ƙarƙashin kulawar likita.

Canje-canje a cikin aikin insulin, nau'ikansa, nau'in (alade, insulin mutum, ƙirar insulin mutum) ko hanyar samarwa (insulin na sake insulin ko insulin asalin dabbobi) na iya buƙatar daidaita sashi.

Ana buƙatar buƙatar yin gyare-gyaren kashi a riga-farko a farkon shiri na insulin ɗan adam bayan shiri na insulin dabbobi ko sannu a hankali a cikin makonni da yawa ko watanni bayan canja wuri.

Bukatar insulin na iya raguwa tare da rashin isasshen aiki, ƙwayar ƙwayar cuta ko glandar thyroid, tare da ƙarancin renal ko hepatic insufficiency.

Tare da wasu cututtuka ko damuwa na damuwa, buƙatar insulin na iya ƙaruwa.

Hakanan ana iya buƙatar yin gyaran fuska yayin ƙara yawan motsa jiki ko lokacin da ake canza abinci na yau da kullun.

Bayyanar cututtukan cututtukan jini a yayin gudanar da aikin insulin na ɗan adam a cikin wasu marasa lafiya na iya zama ƙarancin bayyanawa ko bambanta da waɗanda aka lura yayin gudanar da insulin dabbobi. Tare da daidaituwa na matakan glucose na jini, alal misali, a sakamakon maganin insulin mai zurfi, duk ko wasu alamun alamun alamun hypoglycemia na iya ɓacewa, game da abin da ya kamata a sanar da marasa lafiya.

Bayyanar cututtukan cututtukan cututtukan jini na iya canzawa ko kuma ba a faɗi ƙima tare da tsawan lokaci na ciwon sukari mellitus, mai ciwon sukari, ko tare da yin amfani da beta-blockers.

A wasu halaye, halayen rashin lafiyan gida na iya lalacewa ta hanyar dalilan da ba su da alaƙa da aikin miyagun ƙwayoyi, alal misali, fushin fata tare da wakilin tsarkakewa ko allura mara kyau.

A cikin lokuta mafi ƙarancin halayen halayen ƙwayar cuta, ana buƙatar magani na gaggawa. Wasu lokuta, ana buƙatar canje-canje insulin ko buƙatar bacci.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

A lokacin hypoglycemia, ikon mai haƙuri don tattara hankali zai iya raguwa kuma ƙimar halayen psychomotor na iya raguwa. Wannan na iya zama haɗari a cikin yanayi inda waɗannan damar ke da mahimmanci musamman (tuki mota ko injin aiki). Ya kamata a shawarci marassa lafiya su yi taka-tsantsan don kauce wa hauhawar jini yayin tuki. Wannan yana da mahimmanci musamman ga marasa lafiya da alamu masu raɗaɗi ko rashi-waɗanda suka fara haifar da hypoglycemia ko tare da haɓakar haɓakawar jini. A irin waɗannan halayen, likita dole ne ya kimanta yuwuwar haƙuri na jan motar.

Pharmacokinetics

Cikakken mamayewa da farawar insulin ya dogara da hanyar gudanarwa (subcutaneously, intramuscularly), wurin gudanarwa (ciki, cinya, buttocks), kashi (girman insulin allurar), maida hankali kan insulin a cikin magunguna, da dai sauransu Matsakaicin maida hankali (C max) na plasma insulin ya samu tsakanin 1.5-2.5 hours bayan subcutaneous management. Rarraba

Babu wata ma'anar da ta ambaci sunadaran kare lafiyar plasma, wani lokacin kawai ana gano kwayoyin cuta zuwa cikin insulin.

An cire insulin na mutum ta hanyar aikin insulin protease ko enzymes-insulin share-share, da kuma, ta yiwu, ta hanyar aikin furotin na lalata isomerase. Ana zaton cewa a cikin kwayar halittar insulin na mutum akwai wurare da yawa na share-fage (hydrolysis), amma, babu wani daga cikin metabolites da aka kirkira sakamakon tsinkewar aiki.

Rabin-rabi (T 1/2) an ƙaddara shi da ƙimar ɗimbin yawa daga kasusuwa na kasusuwa. Don haka, T 1/2 shine mafi kusantar ma'aunin sha, maimakon ainihin matakin cire insulin daga plasma (T 1/2 na insulin daga cikin jini kawai 'yan mintuna). Nazarin ya nuna cewa T 1/2 kusan awa 2-5 ne.

Pharmacokinetics a cikin lokuta na musamman na asibiti

An yi nazarin furofayil na kantin magani na Actrapid NM a cikin karamin rukuni na yara masu ciwon sukari mellitus (mutane 18) masu shekaru 6-12, kazalika da matasa (shekaru 13 zuwa 17). Kodayake bayanan da aka samu suna da iyaka, amma duk da haka sun nuna cewa bayanin magunguna na Actrapid NM a cikin yara da matasa sunyi kama da na manya. A lokaci guda, an bayyana bambance-bambance tsakanin tsararraki daban-daban ta hanyar nuna alama kamar C max, wanda kuma ya sake jaddada bukatar zabin kowane kashi.

Sakawa lokacin

Magungunan an yi shi ne don SC da / a cikin gabatarwar.

An zaɓi kashi na miyagun ƙwayoyi daban-daban, la'akari da bukatun mai haƙuri. Yawanci, bukatun insulin ya fara daga 0.3 zuwa 1 IU / kg / rana. Bukatar yau da kullun don insulin na iya zama mafi girma a cikin marasa lafiya tare da juriya na insulin (alal misali, a lokacin balaga, har ma a cikin marasa lafiya tare da kiba), da ƙananan cikin marasa lafiya tare da ragowar insulin na insulin.

Idan masu haƙuri tare da ciwon sukari sun sami daidaitaccen iko na glycemic, to, rikicewar cututtukan sukari yawanci yakan faru ne daga baya. A wannan batun, yakamata mutum yayi ƙoƙari don inganta sarrafa metabolism, musamman, ta hanyar sa ido sosai a kan matakin glucose a cikin jini.

Actrapid NM insulin aiki ne gajere kuma za'a iya amfani dashi hade da insulins masu daukar dogon lokaci.

Ana gudanar da maganin a cikin mintina 30 kafin cin abinci ko abun ciye-ciye wanda ya ƙunshi carbohydrates.

A mafi yawan lokuta ana gudanar da shi ne a cikin farfajiyar yanki na bangon ciki na ciki. Idan wannan ya dace, to kuwa za'a iya yin allura a cinya, yankin gluteal ko kuma a cikin yankin na ƙashin kai na kafada. Tare da shigar da miyagun ƙwayoyi a cikin yankin bangon ciki na ciki, ana samun saurin ɗaukar sauri fiye da gabatarwar zuwa wasu yankuna. Yin aiwatar da allura a cikin fatar fata yana rage haɗarin shiga cikin tsoka.

Wajibi ne a canza wurin allurar a cikin yankin na jiki don hana ci gaban lipodystrophy.

Hakanan zai yiwu, amma likita ne ya ba da umarnin kawai.

Actrapid NM shima ana iya shiga / ciki kuma irin waɗannan hanyoyin za a iya yin hakan ne ta ƙwararren likita.

Tare da lalacewar kodan ko hanta, an rage buƙatar insulin.

Umarnin don amfani da shi

Don gudanarwa na ciki, tsarin jiko wanda ya ƙunshi Actrapid NM 100 IU / ml ana amfani da shi a cikin tarawa daga 0.05 IU / ml zuwa 1 IU / ml na insulin ɗan adam a cikin hanyoyin jiko, kamar 0.9% sodium chloride solution, 5% da mafita 10% dextrose, gami da sinadarin chloride potassium a wani taro na 40 mmol / l, tsarin don / kunnawa yana amfani da jaka na jiko da aka yi da polypropylene, waɗannan mafita suna tabbata a cikin sa'o'i 24 a zazzabi a ɗakin.

Kodayake waɗannan maganganun suna tsayayye na wani ɗan lokaci, a farkon matakin, ɗaukar takamaiman adadin insulin an lura da shi ta hanyar abin da jakar ke sanyawa. A lokacin jiko, wajibi ne don saka idanu kan matakan glucose a cikin jini.

Umarnin don amfani da Actrapid NM, wanda dole ne a ba wa mara lafiya.

Za'a iya amfani da vials tare da miyagun ƙwayoyi Actrapid NM tare kawai tare da sirinji na insulin, wanda akan sa ma'auni, wanda zai ba ku damar auna kashi a cikin raka'a aiki. Vials tare da Actrapid NM an yi niyya ne don amfanin mutum kawai.

Kafin amfani da Actrapid ® NM, ya zama dole: Bincika alamar don tabbatar cewa an zaɓi nau'in insulin daidai, gurɓatar da matattakalar roba tare da huhun auduga.

Ba za a iya amfani da miyagun ƙwayoyi Actrapid ® NM a cikin waɗannan halaye masu zuwa ba:

- a cikin famfo na insulin,

- Wajibi ne ga marasa lafiya suyi bayanin cewa idan babu wata madaidaicin kariya akan sabon kwalban, wacce aka karba daga kantin, ko kuma bata dace ba, irin wannan insulin dole ne a dawo da shi kantin magani.

- idan an adana insulin ba daidai ba, ko kuma a daskararre.

- Idan insulin ya daina nuna gaskiya da launi.

Idan mara lafiyar yana amfani da nau'in insulin guda ɗaya kaɗai

1. Zana iska a cikin sirinji a cikin adadin wanda yayi daidai da adadin insulin da ake so.

2. Sanya iska a cikin kwalin insulin. Don yin wannan, soki matattarar roba tare da allura kuma latsa piston.

3. Juya kwalban sirinji a gefe.

4. Shigar da nauyin insulin da ake buƙata a cikin sirinji.

5. Cire allura daga vial.

6. Cire iska daga sirinji.

7. Tabbatar da cewa maganin insulin daidai ne.

8. Sanya nan da nan.

Idan mai haƙuri yana buƙatar haɗa Actrapid® NM tare da insulin aiki na dogon lokaci

1. Juya babban bututun a cikin tafin hannu har zuwa lokacin da insulin ya kasance fari fat da kuma girgije.

2. Jawo iska zuwa cikin sirinji a cikin adadin wanda yayi daidai da kashi na insulin girgije. Sanya iska a cikin murfin insulin na girgije kuma cire allura daga cikin murfin.

3. Jawo iska zuwa cikin sirinji a cikin adadin wanda yayi daidai da kashi na Actrapid NM (“m”). Shigar da iska cikin akwatin tare da Actrapid NM.

4. Juya murfin tare da sirinji (“m”) juye kuma buga lambar da ake so na Actrapid HM. Cire allurar kuma cire iska daga sirinji. Duba daidai gwargwado.

5. Saka allura a cikin murfin insulin na girgije.

6. Juya murfin tare da sirinji ya juye.

7. Kira kashi da ake so na insulin na hadari.

8. Cire allura daga vial.

9. Cire iska daga sirinji ka bincika cewa kashi ɗin yayi daidai.

10. Sanya nan da nan cakudadden insulin na gajere da
dogon aiki.

Koyaushe ɗauka insulins masu gajeru da tsayi a cikin jeri ɗaya kamar yadda aka bayyana a sama.

Ka umurci mai haƙuri yadda ake sarrafa insulin

1. Tare da yatsunsu biyu, ansu rubuce-rubucen fata, saka allura a cikin gindin murfin a wani kusurwa na kimanin digiri 45, kuma saka allurar a ƙarƙashin fata.

2. Bayan allura, allura ya kamata ya kasance a karkashin fata na akalla awanni 6, don tabbatar da cewa an saka insulin a ciki.

Side sakamako

Abubuwan da ba a sani ba sun lura a cikin marasa lafiya yayin aikin jiyya tare da Actrapid NM sun fi dacewa da kashi-kashi kuma sun kasance saboda aikin maganin insulin. Kamar yadda yake tare da sauran shirye-shiryen insulin, tasirin sakamako mafi yawancin shine hypoglycemia. Yana haɓakawa a cikin yanayi inda adadin insulin ya zarce buƙatarta. A lokacin gwaji na asibiti, kazalika da lokacin amfani da miyagun ƙwayoyi bayan fitarwarsa a kasuwar mabukaci, an gano cewa yawan hypoglycemia ya bambanta a cikin al'ummomin haƙuri daban-daban kuma lokacin amfani da tsarin magunguna daban-daban, don haka ba zai yiwu ba a nuna ainihin ƙimar ƙimar.

A cikin tsananin rauni, asarar hankali da / ko raɗaɗi na iya faruwa, rashi na ɗan lokaci ko na dindindin na aikin kwakwalwa, har ma da mutuwa, na iya faruwa. Nazarin asibiti ya nuna cewa abin da ke faruwa a cikin jini bai bambanta tsakanin marasa lafiya da ke karɓar insulin na mutum da kuma marasa lafiya da ke karɓar insulin.

Followinga'idodi masu zuwa ne na yawan tasirin halayen da aka gano yayin gwaji na asibiti, waɗanda aka ɗauke su da alaƙa da amfani da miyagun ƙwayoyi Actrapid NM. An ƙaddara tazarar kamar haka: sau ɗaya (> 1/1000, Rashin Tsarin rigakafi na rigakafi: naƙasasshe - urticaria, fitsari, da wuya anaphylactic halayen ne.) Alamomin yawan tashin hankali na iya haɗawa da hurawar fata, ƙaiƙayi, sweating, cuta na ciki, angioedema kumburi, gajeriyar numfashi, bugun jini, raguwar hawan jini, sankarar jiki / rashin sahibancin Magana game da yanayin tashin hankali na iya haifar da barazana ga rayuwa.

Rashin hankali daga tsarin juyayi: yana da wuya - neuropathy na gefe. Idan an sami ci gaba cikin kulawar glucose na jini da sauri, yanayin da ake kira "matsanancin raunin neuropathy" na iya haɓaka wanda yake yawan juyawa ne.

Take hakkin rukunin hangen nesa: akai-akai - kurakurai masu sakewa. Damuwa na shakatawa ana yawanci lura a matakin farko na ilimin insulin. A matsayinka na mai mulkin, waɗannan alamu suna juyawa. Da wuya sosai - maganin ciwon sukari Idan an samar da isasshen kulawar glycemic na dogon lokaci, yana rage haɗarin ci gaban cututtukan cututtukan fata. Koyaya, ƙarawar ƙwayar insulin tare da ingantacciyar haɓakawa a cikin sarrafa glycemic na iya haifar da karuwa na ɗan lokaci a cikin tsananin matsalar ciwon sukari.

Rashin daidaituwa daga fata da ƙananan kasusuwa: marasa jinkiri - lipodystrophy. Lipodystrophy na iya haɓaka a wurin allura a cikin lamarin idan ba koyaushe suke canza wurin allura ba a cikin ɓangaren ɓangaren jikin.

Rashin hankali daga jiki gabaɗaya, da kuma halayen a wurin yin allura: ba sau da yawa, halayen a wurin allurar. A kan asalin ilimin insulin, halayen na iya faruwa a wurin allurar (redness na fata, kumburi, itching, soreness, hematoma samuwar a wurin allura). Koyaya, a mafi yawan lokuta, waɗannan halayen suna da natsuwa a cikin yanayi kuma sun ɓace yayin aiwatar da ci gaba da jiyya. Sau da yawa - puffiness. Yawancin lokaci ana lura da kumburi a matakin farko na farjin insulin. A matsayinka na mai mulkin, wannan alamar tana da sauki a yanayi.

Yin amfani da miyagun ƙwayoyi yayin daukar ciki da lactation

Babu ƙuntatawa game da amfani da insulin a lokacin daukar ciki, tunda insulin ba ya ƙetare shingen mahaifa ba. Haka kuma, idan ba a kula da cutar sankara ba yayin daukar ciki, tayin na cikin haɗari. Sabili da haka, dole ne a ci gaba da maganin cutar sankara yayin daukar ciki.

Dukkanin hypoglycemia da hyperglycemia, wanda zai iya haɓaka cikin yanayin da aka zaɓa na rashin dacewa, yana kara haɗarin rikicewar tayin da mutuwar tayi.Ya kamata a sa ido ga mata masu juna biyu masu ciwon suga a duk lokacin da suke cikin ciki, suna buƙatar samun ingantaccen iko na matakan glucose na jini, shawarwari iri ɗaya sun shafi matan da ke shirin daukar ciki.

Bukatar insulin yawanci yana raguwa a farkon farkon ciki kuma sannu a hankali yana ƙaruwa a cikin na biyu da na uku.

Bayan haihuwa, bukatar insulin cikin sauri ta koma matakin da aka lura da shi kafin daukar ciki.

Hakanan babu hani akan amfani da miyagun ƙwayoyi Actrapid NM yayin shayarwa. Gudanar da ilimin insulin ga uwaye masu shayarwa ba haɗari ga jariri. Koyaya, mahaifiyar na iya buƙatar saita tsarin jigilar abubuwa na Actrapid NM da / ko rage cin abinci.

Hulɗa da ƙwayoyi

Akwai kwayoyi da yawa waɗanda ke shafar buƙatar insulin.

Hypoglycemic sakamako na insulin inganta baka hypoglycemic jamiái, monoamine oxidase hanawa, ACE hanawa, carbonic anhydrase hanawa, zabe beta-blockers, bromocriptine, sulfonamides, anabolic steroids, tetracyclines, klofiorat, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, lithium, kwayoyi, dauke da sinadarin ethanol.

Maganin hana daukar ciki, GCS, hormones na thyroid, thiazide diuretics, heparin, maganin tricyclic antidepressants, sympathomimetics, danazole, clonidine, alluran tashar alli, diazoxide, morphine, phenytoin, nicotine sun raunana tasirin maganin insulin.

Underarfafawar tasirin reserpine da salicylates, duka raunana da haɓaka a cikin aikin miyagun ƙwayoyi yana yiwuwa.

Beta-blockers na iya rufe alamun hypoglycemia kuma yana sa ya zama da wahala a kawar da ƙin jinin haila.

Octreotide / lanreotide na iya ragewa da haɓaka buƙatar insulin.

Alcohol na iya haɓakawa da tsawaita sakamako na insulin.

Actrapid NM za'a iya ƙara kawai ga waɗancan mahaɗan waɗanda aka san an dace dasu. Wasu kwayoyi (alal misali, kwayoyi waɗanda ke ɗauke da thiols ko sulfites) lokacin da aka kara su zuwa maganin insulin na iya haifar da lalata.

Sharuɗɗan da yanayin ajiya

Adana a cikin firiji a zazzabi of 2 ° C zuwa 8 ° C (ba kusa da injin daskarewa ba) a cikin kwali. Kar a daskare. Ya kamata a kiyaye miyagun ƙwayoyi daga haɗuwa da zafi da hasken rana. Ayi nesa da isar yara. Rayuwar shelf shine watanni 30. Kada kayi amfani bayan ranar karewa.

Don kwalban da aka buɗe: adana a zazzabi da ba ya wuce 25 ° C na makonni 6. Ba'a bada shawara don adanawa a cikin firiji. Adana kwalban a cikin kwali na kwali don kariya daga haske.