Abin da zai iya maye gurbin Tricor: allunan analogues

Maganin Tricor yana cikin rukunin magunguna masu rage rage yawan lipid - zazzabi. Abinda ke amfani da maganin shine fenofibrate(wanda aka samo shifibroic acid) ana nuna shi ta hanyar sakamako mai kunnawa akan PPARα kuma saboda raguwa a cikin kira Apoprotein CIII da karfafawa lipoprotein lipasehaɓaka lipolysisda kuma hauhawar yawan jini da aka samo daga plasma atherogenic lipoproteinsdauke da adadi mai yawa triglycerides. Kunnawa na PPARα kuma yana haɓaka kira AI da AII na karuwa.

Irin wannan tasiri fenofibratea kunne lipoproteinsyana taimakawa rage abubuwa VLDLda LDLdauke da amo B, da haɓaka murabba'i HDLgami da AI da AII na karuwa. Bugu da kari, aikin fenofibrateda nufin daidaita hanyoyin samar da abubuwan ci gaba VLDL, wanda yake haifar da karuwa a cikin sharewa LDL da rage daskararru mai yawa da barbashi mai kyau LDL(karuwa data LDLlura a cikin marasa lafiya da atherogenic lipid phenotype kuma yana tare da haɓakar haɗarin cututtukan zuciya).

Gwajin Clinical ragewan lipidkaddarorin fenofibrateya nuna raguwa cikin abun ciki triglyceridesby 40-55% kuma jimlar cholesterol ta 20-25% a tsakanin kara matakan HDLby 10-30%. A cikin marasa lafiya tare da hypercholesterolemiamatakin LDLwanda aka rage da kashi 20-35%, magani fenofibratehaifar da raguwa a cikin rabo: jimlar cholesterol da HDL, amo B da apoptein AI, HDLda LDLwaxanda suke da alamun masu saurin hadari atherogenicity.

Lura da babban tasiri fenofibratedon abun ciki triglyceridesda LDLamfani da shi yana da tasiri a cikin marasa lafiya tare da hypercholesterolemiaba tare da la’akari da ko tare da ita ba basirko a'a, hade da sakandare hyperlipoproteinemiakamar misali tare da nau'in 2 ciwon sukari mellitus (aka lura da ingancin Traicor a ciki ciwon sukari) A lokacin jiyya fenofibrateraguwa mai mahimmanci kuma har ma da cikakken ɓataccen adibas ɗin mayuka yana yiwuwa cholesterol(tuberose da tendon xanthomas).

A cikin marasa lafiya tare da wuce kima abun ciki lipoproteinko fibrinogenwadanda aka kula dasu fenofibrate, an lura da raguwa sosai a cikin wannan alamar. Farfesa fenofibratehaifar da raguwa a cikin matakin C-reactive protein da sauran alamun alamun kumburi.

Marasa lafiya tare da hawan jinida dyslipidemiasun sami ƙarin amfanin magani fenofibratewanda ya kunshi sakamako na uricosurichaifar da raguwa cikin abun ciki uric acid kusan 25%.

Karatuttukan dabbobi da nazarin karatun asibiti masu zuwa sun nuna raguwa fenofibratetarawa countlet platesaboda fallasawa adenosine diphosphate, epinephrine da arachidonic acid.

An haɗa allunan Tricor 145 mg micronized fenofibrate a cikin hanyar nanoparticles.

A cikin plasma na mutum, ba a gano fenofibrate na farko ba. Babban samfurin samfurin plasma na ƙwayar cuta yana la'akari fenofibroic acid.

Plasma Cmax fenofibrate ana lura dashi bayan sa'o'i 2-4 bayan sarrafa maganin maganin. Yin amfani da fenofibrate na dogon lokaci baya haifar da canji a cikin ƙwayar ƙwayar plasma, wanda, ba tare da la'akari da yanayin halayen mutum na haƙuri ba, yana tabbata.

Ba kamar shirye-shirye na yau da kullun ba, ana iya aiwatar da sarrafawa na maganin wannan sashi na fenofibrate (nanoparticles) a kowane lokaci na rana, ba tare da la'akari da abinci ba, wanda a wannan yanayin ba zai tasiri matsakaicin ƙwayar plasma na fenofibrate da tasirin gaba ɗaya ba.

Bayan ciwan ciki fenofibrate yana ɗaukar ruwa mai saurin motsa jiki esterasestare da sakin plasma fenofibroic acid (manyan metabolite). Ana ganin ingantaccen haɗi a cikin jini fenofibroic acid tare da albumin(sama da kashi 99%). T1 / 2 na babban metabolite na miyagun ƙwayoyi shine kimanin awanni 20. Fenofibrate ba ya shiga cikin metabolismal metabolism kuma baya ɗaukar matsayin madadin CYP3A4.

Excretion na miyagun ƙwayoyi tare da fitsari ne da za'ayi mafi yawa a cikin hanyar fenofibroic acidkazalika conjugate glucuronide. Kwana shida kenan, ana duba kusan ƙarshen fenofibrate.

Gaba daya sharewa fenofibroic acid ba ya canzawa tare da shekarun haƙuri. Taro na magani ba ya faruwa. Aikace-aikacen maganin hemodialysiscire fenofibrate ba shi da amfani.

Allunan Tricor 160 MG, idan aka kwatanta da nau'ikan warkewa na fenofibrate, ana nuna su ta hanyar bioavailability mafi girma.

A cikin plasma na mutum, ba a gano fenofibrate na farko ba. Babban samfurin samfurin plasma na ƙwayar cuta yana la'akari fenofibroic acid.

Plasma Cmax ana lura dashi bayan sa'o'i 4-5 bayan sarrafa maganin maganin. Yin amfani da fenofibrate na dogon lokaci baya haifar da canji a cikin ƙwayar ƙwayar plasma, wanda, ba tare da la'akari da yanayin halayen mutum na haƙuri ba, yana tabbata. Cutar da wannan nau'in warkewar fenofibrate yana ƙaruwa tare da haɗuwa tare da abinci.

A cikin plasma, kawai babban samfuri na metabolite fenofibrate an gano - fenofibroic acidwanda tabbatacce yana ɗaurewa albuminsama da kashi 99%. T1 / 2 na babban metabolite na miyagun ƙwayoyi shine kimanin awanni 20.

Excretion na miyagun ƙwayoyi tare da fitsari ne da za'ayi mafi yawa a cikin hanyar fenofibroic acidkazalika conjugate glucuronide. Kwana shida kenan, ana duba kusan ƙarshen fenofibrate.

Gaba daya sharewa fenofibroic acid ba ya canzawa tare da shekarun haƙuri. Taro na magani ba ya faruwa. Aikace-aikacen maganin hemodialysiscire fenofibrate ba shi da amfani.

Alamu don amfani

An nuna tricor don amfani dashi don:

  • magani ware ko gauraye hypercholesterolemiada basir(dyslipidemia IIa, IIb, III, IV, V nau'in) idan akwai rashin ƙarfi maganin rage cin abinciko wasu hanyoyin warkewa marasa magani (gami da asarar nauyi, haɓaka aikin jiki, da sauransu), musamman ma a gaban ƙarin abubuwan haɗarin da ke haɗuwa da dyslipidemia(shan taba, hauhawar jini),
  • sakandare far hyperlipoproteinemialokacin adanawa hyperlipoproteinemiakoda a bango na ingantaccen magani na cututtukan cututtukan cuta (alal misali, dyslipidemialura a ciwon sukari).

Contraindications

Dalilin da miyagun ƙwayoyi Tricor ne contraindicated a:

  • nauyi cututtukan hanta (gami da cirrhosis) ko koda(tare da QC kasa da 20ml / min),
  • jigilar mutum ga fenofibrateko wasu abubuwan aikin kwaya,
  • nono
  • sukari rashin haƙuri,
  • pathologies na gallbladder,
  • tarihin mai haƙuri daukar hotoko daukar hotoa lokacinda aka fara shan fibrates ko Ketoprofen,
  • da suka gabata halayen rashin lafiyan halayen a kan soya Lecithin, gyadako man da ke ciki, da abinci iri iri (hadarin kamuwa da cuta),
  • har zuwa shekara 18.

Ana amfani da tricor tare da taka tsantsan yayin da:

  • gazawa hepatic/na kodaayyuka
  • barasa,
  • hawan jini,
  • nauyin tarihin gado cututtukan tsoka,
  • a layi daya liyafar gumaka,
  • cikin tsufa.

Tricor, umarnin don amfani (hanya da sashi)

Allunan na miyagun ƙwayoyi Tricor an yi su ne don gudanar da maganin na baki ɗaya cikin ruwa tare da ruwa (200-250 ml). Umarnin don amfani da Tricor 145 MG yana ba da izinin gudanar da allunan magungunan, ba tare da la'akari da abinci ba, a kowane lokaci dace ga mai haƙuri. Ya kamata a ɗauki allunan kwayoyi 160 na ƙwayoyin cuta tare da abinci.

Jigilar hanyar yin jiyya tare da Tricor yana ɗaukar nauyin guda ɗaya na yau da kullun ta hanyar manya-manyan kwamfyutocin guda ɗaya na 145 mg ko 160 mg. Wadannan nau'ikan sashi na Traicor, kamar yadda aka tsara shirye-shirye tare da fenofibrate abun ciki na 200 MG (alal misali, Lipantil 200 M) ana ɗauka daidai ne, dangane da wane ne, ana yin canjin daga ɗayan magani zuwa wani ba tare da wani sauƙin gyara ba.

Marasa lafiya da ke fama da rauni na aiki na bukatar magani tare da rage allurai na maganin. Marasa lafiya tsofaffi ba sa buƙatar gyaran kashi. Yin amfani da Tricor don lura da marasa lafiya tare dacututtukan hanta ba karatu.

Ya kamata a gudanar da aikin tiyata tare da Tricor na dogon lokaci, a layi daya tare da abinciAn wajabta wa mai haƙuri kafin fara magani. Yakamata likitan halartar yakamata yayi kimanta tasirin maganin. Sharudda game da wannan ƙimar shine ainihin abin da ake amfani da shi lipids(gami da jimlar cholesterol, triglyceridesda LDL) Idan babu wani sakamako na magani bayan watanni da yawa (yawanci bayan watanni 3) na shan allunan Tricor, tambayar ta dacewar amfani da ita gabaɗaya kuma akwai yiwuwar sake duba yanayin.

Haɗa kai

Amfani na yau da kullun na fenofibrate tare da baka anticoagulantsyana haifar da karuwa a cikin tasirin su kuma, sakamakon haka, zuwa haɗarin haɗarin zub da jinisaboda cunkoso fita anticoagulantdaga abubuwan gina jiki. A farkon farawa fenofibratebayar da shawarar ragewa sashi da mai haƙuri ya ɗauka anticoagulantsKusan na uku, tare da ƙarin zaɓi game da gwargwado. Sashi anticoagulantan zaɓe shi daidai da matakin INR.

Tare da haɗin gwiwa yin amfani da fenofibrate da Sankarini da yawa zazzagewa aukuwa da aka lura rage aikin koda. Wannan haɗin magungunan yana buƙatar saka idanu akan yanayin aikin koda da cirewar fenofibrate na lokaci yayin da aka sami canji mai mahimmanci a cikin sigogi na dakin gwaje-gwaje.

Haɗakar amfani da fenofibrate tare da sauran fibrates ko statins yana ƙara yiwuwar mummunan sakamako mai guba dangane da ƙwayoyin tsoka.

Bincike microsomeshanta na mutum (in vitro) ya bayyana rashi tasirin hanawar fenofibrate da babban metabolite - fenofibroic acid a kan isoenzymes cytochrome P450: CYP2D6, CYP1A2, CYP3A4, CYP2E1B, kazalika da ƙarancin inhibitory mai illa akan isoenzymes CYP2C19 da CYP2A6 kuma matsakaici akan CYP2C9.

Umarni na musamman

Bada Tricor ciwon sukari Nau'i na biyu nephrotic syndrome, hawan jini, dysproteinemia, mummunan tasirin magani, hanawacututtukan hanta, barasa da sauran yanayi mai raɗaɗi irin wannan, yana iya yiwuwa ne kawai bayan maganin farko da aka yi niyya don kawar da dalilai na sakandare hypercholesterolemia.

Yakamata likitan halartar yakamata yayi kimanta tasirin maganin. Sharudda game da wannan ƙimar shine ainihin abin da ake amfani da shi lipids (gami da jimlar cholesterol, triglyceridesda LDL) Idan babu wani sakamako na magani bayan watanni da yawa (yawanci bayan watanni 3) na shan allunan Tricor, tambayar ta dacewar amfani da ita gabaɗaya kuma akwai yiwuwar sake duba yanayin.

A cikin marasa lafiya tare da basirana cikin magani da isrogen ko mai masauki na baka hormonal hana haihuwagami da estrogens, ya kamata ya tantance tushen farko ko sakandare na samuwar basirtunda karuwa a matakin lipidsmai yiwuwa saboda liyafar isrogen.

A kan banbancin amfani da Traicor da sauran wakilai na warkewa wanda ke rage matakin lipids, wani lokacin lura da karuwa a cikin abun ciki hepatic transaminases. Mafi sau da yawa, irin wannan ƙaruwa ya kasance na ɗan lokaci, ba shi da mahimmanci kuma yana asymptomatic. A cikin watanni 12 na farko na maganin, Triicor an bada shawarar don saka idanu kan abubuwan tarawa transaminase(AST, ALT) kowane watanni 3. Idan mai haƙuri yana da matakin haɓaka transaminaseyana da Dole a lura da yanayin sa na gaba kuma, tare da haɓaka abun ciki na AST da ALT ta hanyar abubuwa uku a kwatanta da VGN, dakatar da ɗaukar Traicor.

Yayin aikin jiyya, an bayyana abubuwan da ke faruwa ta Tricor. maganin ciwon huhu. Abubuwanda ke iya haifar da wannan cutar a cikin wannan yanayin sune: Ingantaccen aikin jiyya mara ƙima a cikin marasa lafiya tare da mai rauni basir, tasirin maganin kai tsaye, da kuma abubuwanda suka sakankance da kasancewar gallstones ko samuwar laka a ciki, tare da toshewar bututun da ake amfani da shi.

Amfani da Tricor, kamar sauran magunguna waɗanda ke rage abun cikin lipids, na iya haifar da sakamako masu guba a kan ƙwayar tsoka, har zuwa haɓaka rhabdomyolysis(a cikin mafi yawan lokuta). Mitar irin waɗannan maganganun yana ƙaruwa lokacin da mai haƙuri yana da tarihin na gazawar da hypoalbuminemia. Dakatar da sakamako mai guba na miyagun ƙwayoyi akan ƙwayar tsoka yana barata a yanayin mai kararrakin marasa lafiya myositisrauni jijiyar wuya kuma rarrafe, yadawa myalgia, kazalika da alamar ƙaruwa a cikin aiki halittar phosphokinase(sau biyar sama da VGN). A cikin waɗannan halayen, ya kamata a dakatar da jiyya tare da Tricor.

Hadarin halitta rhabdomyolysisƙaruwa a cikin marasa lafiya annabta zuwa rhabdomyolysisda / ko myopathiesgami da tsufa (sama da shekara 70), shan giyanauyin da tarihin gado na tsoka cuta, hawan jini, lalataccen aikin na koda. Ana iya tsara marasa lafiya na waɗannan rukunin Tricor kawai idan akwai babban adadin amfanin amfanin magani idan aka kwatanta da yiwuwar haɗarin samuwar rhabdomyolysis.

Haɗin fenofibrate tare da wasu fibrates ko statins yana ƙaruwa da yiwuwar ciwo mai tsanani illa mai guba dangane da ƙwayoyin tsoka, musamman tare da na baya cututtukan tsoka. A saboda wannan dalili, magani na yau da kullun tare da Tricor da gumakabarata ne kawai idan mai haƙuri ya gauraye dyslipidemiamai tsanani da hadarin gaske rikitarwa na zuciya, in babu tarihin sa cututtukan tsokada kuma ƙarƙashin halayen kulawa koyaushe na sakamako mai guba akan ƙwayar tsoka.

Game da matakin karuwa creatininefiye da sau ɗaya da rabi sama da VGN, ya kamata a dakatar da maganin tare da Trikor. A cikin watanni 3 na farko na jiyya, ya kamata a sa ido akan abubuwan da suka dace akan lokaci-lokaci.

Formaddamar da tsari da abun da ke ciki

Hanyar sakin sakin Traicor shine allunan da aka sanya a fim din: dumin, fararen fata, rubutu "145" ko "160" a gefe guda (dangane da sashi), a wani - tambarin kamfanin (a cikin blisters na inji 10., A cikin kwali mai kunshe 1 –5, 9 ko 10 blisters, a cikin blisters na 14 inji mai kwakwalwa., A cikin kwali na kwali na 2, 6 ko 7 blisters).

Abun ciki 1 kwamfutar hannu:

  • abu mai aiki: fenofibrate - 145 (micronized) ko 160 mg,
  • magabata (145/160 mg): sucrose - 145/0 mg, sodium lauryl sulfate - 10.2 / 5.6 mg, lactose monohydrate - 132 / 138.4 mg, crospovidone - 75.5 / 96 mg, microcrystalline cellulose - 84.28 / 115 MG, colloidal silicon dioxide - 1.72 / 12.6 mg, hypromellose - 29/0 mg, docusate sodium - 2.9 / 0 mg, magnesium stearate - 0.9 / 0 mg, sodium stearyl fumarate - 0 / 6.4 mg, povidone - 0/160 MG,
  • harsashi (145/160 mg): Opadry OY-B-28920 (titanium dioxide - 8.03 / 8.96 mg, polyvinyl barasa - 11.43 / 12.75 mg, soya lecithin - 0.5 / 0.56 mg , talc - 5.02 / 5.6 mg, xanthan gum - 0.12 / 0.13 mg) - 25.1 / 28 mg.

Pharmacokinetics

A cikin plasma, ba a gano fenofibrate na farko ba. Babban metabolites plasma shine fenofibroic acid.

Matsakaicin yawan abu a cikin jini yana gudana ne bayan sa'o'i 2 - 4 (145 a kowace) ko kuma awanni 4-5 (maganin mil 160 a kowane) bayan maganin maganin Tricor. Yawan maganin ƙwayar cutar ta plasma na tsawon lokacin yana tsayayye kuma baya dogaro akan halayen mutum na haƙuri.

Tsarin Tricor a cikin MG na 145 ya haɗa da fnofibrate na micronized a cikin nau'ikan nandano. Bambanci tsakanin wannan nau'in sakin daga nau'ikan sashi na fenofibrate shine mafi girman maida hankali ga ƙwayar plasma da kuma tasirin fenofibrate gaba ɗaya a cikin nau'in nanoparticles. Ingancin maganin ba ya dogara da cin abinci ba, sabili da haka ana iya amfani dashi ba tare da la'akari da yawan abinci ba a kowane lokaci.

Aukar fenofibrate lokacin amfani da Tricor 160 MG yana haɓaka yayin ɗauka tare da abinci.

Fiye da 99% na fenofibroic acid an ɗaure shi da ƙarfi zuwa plasma albumin.

Rabin rayuwar fenofibroic acid shine kimanin awanni 20.

Fenofibrate bayan maganin baka yana da saurin inganta ruwa ta hanyar esterases. Sai kawai babban metabolite dinsa mai aiki, fenofibroic acid, ana samunsa a cikin plasma.

Fenofibrate ba wani canji bane ga CYP3A4. Ba ya shiga cikin metabolism metabolism.

Nishadi yana faruwa ne musamman da fitsari a cikin hanyar conjugate na glucuronide da fenofibroic acid. Ana cire Fenofibrate kusan gaba ɗaya a cikin kwanaki 6.

Bayan kashi ɗaya da kuma lokacin tafiya mai tsayi, ƙwayar ba ta narkewa.

Tare da maganin hemodialysis ba a nuna shi ba.

Umarnin don amfani

Tricor wakili ne mai saurin rage kiba. Tushen maganin shine fenofibrate, wani abu ne wanda ya ƙunshi ƙungiyar abubuwan da ke cikin tushen fibroic acid. Akwai shi a cikin nau'ikan Allunan don maganin baka.

Ragearin sarari masu launin fari, tare da haɗari tare da ɗayan tambarin kamfanin a wannan bangaren. Sayarwar samfura a cikin magunguna iri-iri: 145 MG ko 160 MG. Ana amfani dasu akan shawarar likita bayan ƙaddamar da cutar.

Shan Traicor yana taimaka wajan rage matakin triglycerides a cikin jini. An tsara maganin don rage VLDL, LDL, kazalika da haɓaka antiatherogenic HDL.

Duk da yaduwar amfani da sinadaran a magani, har yanzu ba'a yi cikakken nazari kan aikin fenofibrate ba.

Tasirin shirye-shiryen da aka danganta da shi an kunna shi ta hanyar kunna lipoprotein enzyme, da kuma ikon rage jinkirin samar da mayukan kitse. Abun da ke aiki na Tricor yana haɓaka haɓaka adadin masu karɓa na LDL a cikin ƙwayoyin hanta. Tsarin kwalakwala yana raguwa. A cikin marasa lafiya da ciwon sukari mellitus bayan gudanarwa, an lura da raguwar matakan glucose jini.

An wajabta Tricor ga marasa lafiya da ke fama da rauni a zuciya, marasa lafiya da cututtukan da ke tafe:

  • hyperlipoproteinemia na nau'ikan IIa, IIb, III da IV,
  • basantankara,
  • hypertriglyceridemia, idan abincin da likitan ya hada ba shi da sauran taimako don ci gaba da kula da kwalakwalar al'ada kuma ba zai yiwu a daidaita sigogi ba tare da magani ba.

Kuna iya siyar da magani a cikin kantin kan farashin 700 rubles. har zuwa 900 rub. don shiryawa.

Cikin gida

Analog na Rashanci na Tricor na miyagun ƙwayoyi shine Fenofibrat Canon. Kuna iya samun daidaituwa a kusan kowane kantin magani a farashi mai araha. Matsakaicin matsakaici bai wuce 400 rubles ba., A farashin Tricor daga 800-850 rubles. kuma sama.

Fenofibrate Canon yana samuwa a cikin nau'ikan allunan don sarrafawa na baka sashi na 145 MG mai rufi fim. Matsakaicin farashin wannan analog na Traicor shine 500 p.

Shiryawa: marufi - 30 Allunan. Abunda yake aiki shine fenofibrate (daidai yake da na asali).

Aikace-aikacen don waɗannan take hakki:

  • cututtuka na tsarin zuciya da jijiyoyin jini,
  • hyperlipoproteinemia na nau'ikan IIa, IIb, III, IV,
  • basantankara,
  • basir.

Babu bambance-bambance a tsarin liyafar. Manuniya don amfani iri ɗaya ne kamar na Tricor na miyagun ƙwayoyi.

Madadin kasashen waje na Tricor, waɗanda suke da irin wannan tasirin a jiki: Lipantil 200 M, Lofat, da kuma Nofibal.

Likitocin da ke halartar ne kawai ya kamata su zabi maganin da ya dace don magani.

Lipantil 200 M

Lipantil 200 M yana samuwa a Rasha da Faransa. Tsarin tallace-tallace: capsules 200 MG. Farashin su yayi kasa da farashin Tricor.

A cikin kantin magani Lipantil 200 M, ana siyar da shi akan 700-750 rubles. kowace kunshin, kowannensu ya ƙunshi capsules 30 masu yawa masu ruɓi, mai rufi tare da farin kayan shiga ciki.

Abunda yake aiki, kamar yadda yake game da magungunan da suka gabata, shine fenofibrate. Yawan sashi a cikin kwalliyar kwalliya, wanda aka tsara don kashi ɗaya ya fi na Traicor.

Kafin yin amfani da shi, a hankali karanta umarnin kuma ƙayyade adadin kullun da likita ke buƙata. Magungunan suna da ƙuntatawa na shekaru ga marasa lafiya.

Wani nau'in Traicore da aka samar a Faransa shine Lofat. Abubuwan da ke haifar da sakamako mai warkewa shine fenofibrate. Ana siyar da miyagun ƙwayoyi a cikin nau'in capsules mai rufe kayan ciki. Sashi - 250 MG. Wani wakili mai rage rage karfin jini yayi amfani da yawan cututtukan su kamar magungunan da suka gabata. Farashin dillalan Lofat kusan 600 rubles ne. A halin yanzu babu a cikin magunguna.

Nofibal wakili ne na maganin cututtukan jini a jikin kwalliya. An tsara shi dangane da fenofibrate. The odan liyafar daidai ne ga analogues.

  • ammafari (irina IIa),
  • Kwayar cuta mai karya jini (nau'in IV),
  • hypercholesterolemia.

Ana sake yin rajista da miyagun ƙwayoyi kuma a halin yanzu babu a cikin magunguna.

Wani likita ya ba da Nofibal ta likita lokacin da aka gano ƙwayar cutar sankarar mahaifa. An tsara maganin a hade tare da abinci da kuma motsa jiki na musamman. Kuna buƙatar shan magani a 400 ml a rana.

Kodayake duk da babban sashi, babu wasu sakamako masu illa, an yarda da shi sosai. Da farko, an gano hanyoyin da aka nuna a cikin umarnin. Kuna iya yin hukunci game da tasirin sakamakon binciken.

Lipantil 200 M magani ne mai kyau. Sanya shi don lura da jijiyoyin jini, rage ƙwayar cholesterol. Yanayin ya kasance mai rikitarwa ta hanyar kiba da hauhawar jini. Abincin da ya haɗu da abinci mai kyau kawai, wanda aka yarda da shi ba ya taimaka, kamar sauran shawarar likita.

Dole ne in koma ga wakilan magunguna. Likita ya lura da sakamakon bayan kammala karatun. Cholesterol ya ragu. Bugu da ƙari, nauyi ya ragu kuma kumburi ya tafi. Capsules ƙanƙane a cikin girman, saboda haka sun dace don ɗauka. Kuna buƙatar sha sau ɗaya a rana.

Farashi a cikin kantin magani

Bayani game da farashin Tricor a cikin magunguna a Rasha an karɓa daga bayanan magungunan kan layi kuma na iya ɗan bambanta da farashin a yankin ku.

Kuna iya siyar da magani a cikin kantin magunguna na Moscow a farashin: Tricor 145mg 30 Allunan - daga 834 zuwa 845 rubles.

Yanayin bayarda magunguna daga magunguna shine takardar sayan magani.

Adana a cikin busassun a yanayin zafi har zuwa 25 ° C. Ayi nesa da isar yara.

Jerin analogues an gabatar dashi a kasa.

Me ke taimaka wa Tricor 145 da 160 MG?

An wajabta maganin Tricor a cikin halaye masu zuwa:

  • Hypercholesterolemia da hypertriglyceridemia ware ko gauraye (nau'in dyslipidemia iia, sayar, III, IV, V) (tab. 145 mg) da (nau'in dyslipidemia iia, sayarwa, III, IV, V) (shafin 160 MG) a cikin marasa lafiya don wanene rage cin abinci ko wasu matakan magani marasa magani (misali, asarar nauyi ko ƙara yawan motsa jiki) sun kasance masu tasiri, musamman idan akwai abubuwan haɗari da suka shafi dyslipidemia, kamar hauhawar jini da shan sigari,
  • Sakandare hyperlipoproteinemia a cikin lokuta inda hyperlipoproteinemia ya ci gaba duk da ingantaccen magani na cutar rashin lafiya (alal misali, dyslipidemia a cikin ciwon sukari mellitus).

Lokacin amfani da miyagun ƙwayoyi ya kamata ya bi abinci.

Sakamakon Gefen Tricor

Jagorori don amfani da gargaɗi game da yiwuwar haɓaka sakamako masu illa na Magani:

    Daga tsarin narkewa: (> 1/100, 1/1000, 1/10 000, 1/1000, 1/10 000, 1/10 000, 1/1000, 1/1000, Contraindications

An contraindicated don amfani da Tricor 145 a cikin wadannan cututtuka ko yanayi:

  • hypersensitivity to fenofibrate ko wasu abubuwan magunguna,
  • mummunan gajiyawar hanta (gami da cirrhosis),
  • mai tsanani gazawar koda (Cl creatinine overdose

Ba'a yiwa rajistar magungunan cutar yawan ƙwayoyi ba, koyaya, don guje wa halayen da ba su da kyau, ba da shawarar ƙetare adadin da aka nuna a cikin umarnin ba.

Idan akwai haɗari mai yawa na allunan masu yawa, ana bada shawara don sa kwayar ciki, idan ya cancanta, kurkura ciki kuma ku ba allunan enterosorbent.

Jerin analog na Tricor

Idan ya cancanta, maye gurbin miyagun ƙwayoyi, zaɓuɓɓuka biyu suna yiwuwa - zaɓin wani magani tare da abu ɗaya mai aiki ko magani tare da tasiri mai kama, amma tare da wani abu mai aiki.

Analogs na Tricor 145, jerin magunguna:

  1. Lipantil 200 M,
  2. Canjin Fenofibrat
  3. Fitowa.

Makamantan kwayoyi:

Lokacin zabar musanya yana da mahimmanci a fahimci cewa farashin, umarnin don amfani da sake dubawa na Tricor 145 basu shafi analogues ba. Kafin maye gurbin, yana da mahimmanci don samun yardar likitan halartar kuma kada ku maye gurbin maganin ba da kansa.

Nazarin game da Tricor 145 MG ba kaɗan ba ne kuma mai ma'ana. Wasu likitoci za su yi nasarar amfani da shi don daidaita bayanan marasa lafiyar su, lura da fa'idodin wannan magani kuma sun gamsu da sakamakon farfaɗo tare da amfani. Sauran masana suna lura da aikin Traicor da taka tsantsan da lura cewa yiwuwar sakamako masu illa na miyagun ƙwayoyi (ginin dutse, rhabdomyolysis, daukar hoto) ya fi ƙarfin tasirinsa.

Bayanai na Musamman ga Masu Bayar da Kiwon Lafiya

Yardajewa

Amfani da keɓaɓɓen amfani da fenofibrate tare da maganin anticoagulants na baki yana haifar da karuwa a tasirin su kuma, sakamakon haka, zuwa haɗarin haɗarin zub da jini sakamakon fitowar maganin ƙin abinci daga abubuwan haɗin furotin. A farkon maganin fenofibrate, ana bada shawarar rage yawan magungunan anticoagulants da mai haƙuri ya rage da kashi daya bisa uku, tare da karin zabin abubuwan da suka dace. Dos na anticoagulant an zaɓi shi gwargwadon matakin INR.

Tare da yin amfani da fenofibrate da cyclosporin a hade, an lura da yawancin wurare masu rauni na raguwa da ke faruwa a aikin renal. Wannan haɗin magungunan yana buƙatar saka idanu akan yanayin aikin koda da cirewar fenofibrate na lokaci yayin da aka sami canji mai mahimmanci a cikin sigogi na dakin gwaje-gwaje.

Haɗakar amfani da fenofibrate tare da sauran fibrates ko statins yana ƙara yiwuwar mummunan sakamako mai guba dangane da ƙwayoyin tsoka.

Nazarin microsomes na hanta mutum (in vitro) ya bayyana rashi sakamako na inhibitory na fenofibrate da babban metabolite, fenofibroic acid, akan P450 cytochrome isoenzymes: CYP2D6, CYP1A2, CYP3A4, CYP2E1B, kazalika da rauni inhibitory C2 CP da C2 da kuma C2

Umarni na musamman

Ya kamata a gudanar da magani a hade tare da abincin cholesterol kuma a ƙarƙashin kulawar likita.

In babu sakamako mai gamsarwa bayan watanni 3-6 na gudanarwa, ana iya tsara magunguna masu haɗari ko madadin magani.

An bada shawara don saka idanu kan ayyukan “cututtukan hepatic” duk watanni 3 a farkon shekarar far, hutu na wucin gadi a jiyya idan ayyukansu ya ƙaru, da kuma warkewa daga kulawa na lokaci daya na magungunan hepatotoxic.

Maganin HypolipPs Tricor: umarnin don amfani, farashi, sake dubawa da kuma alamun maganin

Allunan kwayoyi na Tricor duka 145 da 160 MG suna da abu mai aiki a cikin nau'i na fenofibrate.

Amma ga aikin magunguna, yana rage rage kiba (ko kuma rage yawan lipids). Magungunan yana cikin rukunin magungunan fibrates.

Gabaɗaya halayen

Asali, ana amfani da miyagun ƙwayoyi don cututtukan cututtukan da ke da alaƙa da:

  • tare da duka insulin-dogara da wadanda ba insulin-dogara da cutar ciwon sukari mellitus,
  • tare da hypercholesterolemia (babban cholesterol a cikin jini), hyperglyceridemia (wuce kima triglycerides),
  • tare da gaurayewar hyperlipidemia (matakan jini masu yawa na cholesterol da mai, da triglyceride),
  • kazalika da sauran cututtukan cututtukan zuciya.

Dangane da hyperlipidemia, zamu iya cewa sune babbar barazanar zuciya da jijiyoyin jini da babban dalilin mutuwa, alal misali, a wata ƙasa kamar Amurka.

Game da bayani kan membobin Tricor a cikin wani rukunin asibiti da masana'antar magunguna, masana'antun suna ba da umarnin Recipharm Monts, da kuma Laboratoies Fournier S.A. shi ba ya nan.

Aikin magunguna da alamomi

A lokacin gwaji na miyagun ƙwayoyi Tricor kai tsaye a cikin dakunan shan magani, binciken da aka yi kan marasa lafiya ya nuna cewa tare da taimakon fenofibrate, an rage yawan kwayar cholesterol a cikin marasa lafiya ta 20, ko ma duka 25%, kuma game da rage yawan triglycerides ɗin, wannan nuna alama yana daga 40 kuma har zuwa 55%.

Magungunan Tricor 145 MG

Haka kuma, a cikin marasa lafiya tare da hypercholesterolemia, yawan jimlar da cholesterol LDL ke raguwa. Ya kamata a ɗauka cewa wannan rabo yana ɗaya daga cikin masu yanke shawara game da haɗarin cutar haɗarin cututtukan zuciya.

MagungunaAn nuna hakan a matsayin ƙari ga hanyoyin rashin magani. Ga irin su motsa jiki na jiki daban-daban, hanyoyin yin asarar nauyi, kazalika da amfani da abinci don abinci:

  • mai cutar hauhawar jini,
  • cakuda hyperlipidemia, idan akwai cututtukan ƙwayoyin cuta na ƙwayoyin jikin jini (ƙwayoyin da ke rage ƙwaƙwalwar jini),
  • cakuda hyperlipidimia. Lokacin da marasa lafiya ke da babban haɗarin cututtukan zuciya da jijiyoyin bugun jini,
  • kuma an ba da allunan a gaban ciwon sukari a cikin yanayin lokacin da abincin da aikin jiki ba su da tasiri.

Fenofibrate wani abu ne wanda aka samo daga fibric acid. Yana canza rabo na lipids a cikin jini.

Yayin aikin jiyya, ana lura da canje-canje masu zuwa:

  • karuwa yarda ko tsarkakewa jini,
  • a cikin marasa lafiya da haɗarin cututtukan zuciya na zuciya, matakin lipoproteins na atherogenic yana raguwa (rabo, wanda ke kara haɗarin atherosclerosis) ko "mummunan" cholesterol,
  • yana taimakawa wajen haɓaka cholesterol "mai kyau",
  • ikon rage intravascular adibas an rage muhimmanci,
  • matakin fibriogen ya ragu,
  • jini yana rage abun cikin uric acid, haka kuma sinadarin C-mai mayar da martani a cikin plasma din.

Matsakaicin abun cikin fenofibrate a cikin jini yana faruwa ne a cikin 'yan' yan awanni bayan ɗaukar mara lafiya Tricor.

Ko da a lokuta na tsawaitawa tare da magani, wannan ba ya haifar da tarawa a cikin jiki.

An cire ta baki ɗaya cikin kwanaki 6-7 musamman tare da fitsari. A lokaci guda, fenofibrate ba a keɓancewa lokacin hemodialysis, tunda ya juya ya zama mai ɗaure sosai ga ƙirar plasma (babban furotin).

Ciki

Game da bayani kan gwaji na asibiti kuma kan aiwatar da maganin ta mata masu juna biyu, to bai isa ba.

Misali, a gwaje-gwajen da dabbobi, ba a gano tasirin tetratogenic (ci gaba da tayi a jikin kwayar cutar).

Haka kuma, yayin aiwatar da gwaji na kwalliya, an bayyanar da ciki a sakamakon amfani da daya daga cikin mata masu juna biyu tare da yawan magunguna. Koyaya, har yanzu ba a ƙaddara haɗarin mata masu juna biyu ba.

Dole ne a wajabta maganin Tricor ga mata masu juna biyu bayan tantance duka amfanin da haɗarin da za su iya samu.

Allurai da Zamani

Muhimmin sani! Mutane sun koyar da haushi don haɓaka matakan sukarinsu ...

Ana ɗaukar maganin a baka, yayin wanke kwamfutar hannu da ruwa. Lokacin cin abincin yana mai sabani ne kuma baya dogaro da abincin (Tricor 145). Yarda da Tricorr 160 ya kamata a aiwatar da lokaci ɗaya tare da abinci.

Kudin don marasa lafiya shine kwamfutar hannu 1 a kowace rana.

Haka kuma, idan marasa lafiya a baya sun dauki kwayar miligrams 160 na Tricor, to, zasu iya, idan ya cancanta, canzawa zuwa shan miligram 145 na maganin, kuma ba tare da daidaitawar kashi ba. Marasa lafiya a cikin tsufa ya kamata su ɗauki madaidaicin kashi - ba fiye da kwamfutar hannu 1 a kowace rana sau ɗaya ba.

Ba a yi nazarin tasirin maganin a kan cututtukan da yara da hanta ba. Ko da sake dubawa a wannan yanayin sun saba wa juna. Saboda haka, yakamata Taykor ya kamace shi ta irin wannan marassa lafiyar da ke taka tsantsan.

Magungunan yana da dogon lokaci na amfani, yayin da ya kamata ku bi abincin da aka wajabta a baya. Kimantawa game da tasiri na maganin Tricoror yakamata a gudanar da shi ta hanyar likita mai halartar yayin nazarin abubuwan da ke tattare da lipids (fats da abubuwan da suke kama da shi), da LDL, yawan ƙwayoyin cuta, da kuma abubuwan da ke cikin triglycerides.

Game da batun lokacin da tsawon watanni ba a gan tasirin warkewa ba, to ya kamata a bincika zaɓuɓɓukan magani na dabam.

Akwai madadin magungunan Tricor

Cannon Fenofibrate (Allunan) Rating: 96 Top

Analog ne mai rahusa daga 424 rubles.

Fenofibrat Canon abu ne mai rahusa kuma yafi riba mai amfani akan aikin gida. Hakanan ana samunsu a cikin allunan kuma sun ƙunshi abu guda mai aiki, amma a farashin mai rahusa fiye da Tricor. Dangane da alamu don amfani da contraindications, babu wani bambanci mai mahimmanci tsakanin magunguna.

Lipantil 200 M (capsules) Rating: 45 Sama

Analog ne mai rahusa daga ruble 69.

Lipantil 200 M ya bambanta da Tricor a cikin nau'in saki kuma ana sayar da shi a cikin capsules, mai shiga cikin kayan ciki. Abubuwan da ke aiki sunyi kama, amma a cikin ɗan ƙaramin sashi mafi girma a kowace maganin. Akwai contraindications da ƙuntatawa na shekaru, don haka kafin fara magani, muna ba da shawara sosai cewa ku karanta umarnin don amfani.

Farashi da analogues

Farashin Tricor a cikin kantin magunguna na iya zuwa 500 da har zuwa 850 rubles, gwargwadon sigogi masu nauyi (145 ko 160 mg), da kuma kan masana'anta. Haka kuma, ainihin farashin na iya bambanta mai mahimmanci daga farashin da aka gabatar akan wuraren kantin magani.

Kamar yadda analogues na Tricor, kwayoyi irin su:

Su ne mafi arha fiye da Tricor, suna da jerin abubuwan contraindications, kazalika da sashi, wanda likita dole ne ya ƙaddara. Kyakkyawan aikace-aikacensu na 'yanci.

Tricor: sake dubawa

Reviews game da miyagun ƙwayoyi Tricor mafi yawa tabbatacce:

  • Yuri, Lipetsk, 46 years old. Amma game da sukari, ba ya rage shi, kuma Tricor yana yaƙi da kyau tare da cholesterol. Koyaya, ana buƙatar sarrafawa ta amfani da nazarin halittu,
  • Elena, Belgorod, 38 years old. Yanayin gabaɗaya ya inganta. Ina ɗan shan kwayoyi kusan wata ɗaya yanzu, da alama dai na yi asara. Ba da daɗewa ba, a nacewar likita, za a gwada ni. Ina fatan lokacin watanni uku masu zuwa,
  • Boris, Moscow, shekara 55. Ina shan maganin Tricor a cikin darussan na watanni 3. Inganci a cikin maganata don rage triglycerides.

Duk abin da kuke buƙatar sani game da Tricor a cikin bidiyon:

Tricor - magani ne don rage cholesterol na jini

Tricor yana ɗayan magungunan rage ƙwayar cutar lipidwanda kuma ake kira fibrates.

Wannan sunan yana faruwa ne saboda babban bangaren aiki - fenofibrate. Maganin asalin fibroic acid ne.

A ƙarƙashin tasirinsa, an rage haɗin apoprotein CIII, sannan kuma ƙarfafa lipoprotein lipase yana farawa, wanda ke inganta lipolysis kuma yana haɓaka saurin fitar da atherogenic lipoproteins daga jini wanda ke ɗauke da triglycerides.

Aiki mai aiki na fibroic acid da abubuwanda ke ciki zasu iya kunna PPARa da haɓaka aikin haɗin AI da apoptoreins.

Fenofibrates kuma yana daidaita catabolism da kuma samar da VLDL. Wannan yana haifar da sharewar LDL da raguwa a cikin yawan ɗimbinsa da ƙananan barbashi.

Kuna iya karanta sake dubawa game da amfani da wannan magani a ƙarshen labarin a cikin sashe na musamman.

Hanyar aikace-aikacen

Ana ɗaukar allunan a baki a baki ɗaya. Dole ne a hadiye su da ruwa da yawa.

Wajibi ne a sha magani a kowane lokaci, ba tare da la'akari da abinci don miyagun ƙwayoyi tare da maida hankali kan abu mai aiki na milimita 145 ba. Lokacin amfani da magani tare da sashi mafi girma, wato, 160 MG, allunan ya kamata a sha lokaci guda tare da abinci.

Ga manya, ana yin allurar 1 kwamfutar hannu sau ɗaya a rana. Mutanen da ke shan Lipantil 200M ko Tricor 160 na iya fara amfani da Tricor 145 a kowane lokaci ba tare da canza sashi ba. Ba tare da canza sashi ba, mai haƙuri na iya juyawa daga shan Lipantil 200M zuwa Tricor 160.

Tsofaffi mutane iri daya magani aka wajabta kamar yadda ya saba.

Tare da na koda ko gazawar hanta da kashi ne pre-tattauna tare da halartar likita.

Tricor wajabta don amfani mai daɗewa a ƙarƙashin halayen abinci na wajibi, wanda aka yi rajista kafin alƙawarin wannan kayan aiki. Likita zai iya yin nazarin amfani da lipids din cikin jini. Idan tasirin da ake so bai faru tsakanin aan watanni ba, to an canza magani.

Ba a lura da yawan abin sha da yawa na miyagun ƙwayoyi ba, amma idan kowane alamun ya faru, to lallai ne a kula da cututtukan ƙwayar cuta.

Yi amfani da allunan kawai bayan shawara tare da likitan ku. Kada ku rubanya magunguna da kanku. Za'a iya siyan tricor kawai ta hanyar takardar sayan magani.

Nau'i na saki, abun da ke ciki

Akwai wadatar Tricor a cikin nau'ikan allunan Alllong, wanda aka sanyaya tare da harsashi na bakin ciki mai launin fari mai haske. Allunan an sanya su da rubutu. Ana nuna lambar 145 a gefe ɗaya, an sanya tambarin na HUOURU a gefe na biyu.

Akwai allunan 145 MG. Kunshin yana iya ɗaukar abubuwa 10 zuwa 300. Hakanan akwai nau'i na saki tare da sashi na 160 mg na abu mai aiki. Packageaya daga cikin kunshin zai iya ƙunsar daga 10 zuwa 100 guda. A cikin akwatin kwali daya wanda aka samar da maganin, akwai blister 3 tare da allunan da umarnin.

A cikin abun da ke cikin miyagun ƙwayoyi, babban aiki shine micronized fenofibrate.

Componentsarin abubuwan da aka gyara sune:

  • lactose monohydrate,
  • sodium lauryl sulfate,
  • yi nasara
  • sabbinne,
  • docusate sodium
  • silica
  • Sankarinka
  • magnesium stearate,
  • maganin lauryl.

Shell din ya hada da Opadry OY-B-28920.

Bidiyo: "Atherosclerosis - a sakamakon babban cholesterol"

Side effects

Tricorrh yana da wasu sakamako masu illa, bayan gano wanne ya zama dole a soke amfani da wannan magani kuma a nemi likita.

Matsaloli da ka iya:Raba:
  • abubuwan dyspeptik
  • babban aikin hanta enzymes,
  • ciwon ciki
  • rarrafewa da rauni na tsoka,
  • tashin zuciya
  • amai
  • yadawo myalgia,
  • ciwon kai
  • rashin tsoro
  • zawo
  • ƙaru cikin taro na jini na leukocytes da haemoglobin,
  • kurji
  • itching
  • lalatawar jima'i
  • cututtukan mahaifa
  • alopecia
  • zurfin jijiya jini.
  • ciwon kai
  • karuwar ayyukan CPK,
  • halayen rashin lafiyan fata
  • hepatitis
  • maganin ciwon huhu
  • serara yawan tara ƙwayoyin transaminase,
  • babbar cuta,
  • fitowar gallstones,
  • sabunna
  • myositis
  • ƙaru cikin taro na urea da creatinine,
  • rhydomyolysis,
  • rashin lafiyar hanji
  • daukar hoto.

A lokacin daukar ciki

Tricor yana ba da kariya ga mata masu juna biyu da kuma mata yayin shayarwa.

Koyaya, gwajin asibiti da ke tabbatar da mummunan sakamako akan tayin ba a gudanar da shi ba. Koyaya, amfrayo ya bayyana a lokacin sanya allurai mai guba ga jikin mace mai ciki. Kodayake ba a yi amfani da maganin ba ga mata masu juna biyu, a wasu halaye an sanya mata ga wannan lokacin yayin tantance rabo da haɗarin.

Hakanan, ba'a gano tasirin Tricor akan yara lokacin shayarwa ba, don haka likitoci sunyi ƙoƙarin kada su sanya wannan magani a wannan lokacin.

Sharuɗɗan da yanayin ajiya

Dole ne a ajiye tricor a cikin kunshin masana'anta. Bugu da ƙari, zazzabi ɗin ajiya mai izini shine digiri 25.

Rayuwar shiryayye na miyagun ƙwayoyi ya dogara da maida hankali kan abu mai aiki a cikin miyagun ƙwayoyi. Lokacin sayen allunan a cikin sashi na 145 MG, rayuwar shiryayyen su na iya kaiwa shekaru 3. Lokacin amfani da allunan a cikin sashi na 160 mg, rayuwar shiryayye an rage shi shekara guda kuma shekara 2 ne.

Farashin magungunan ba kawai ya dogara da girman kunshin ba (girman kwamfutar hannu da ke ciki) wanda aka samar dashi, amma kuma akan maida hankali akan abu mai aiki.

Matsakaicin farashin a Ukraine

Kuna iya siyan Tricor a Ukraine akan farashi daga 349 zuwa 400 hryvnias kowace fakitin miyagun ƙwayoyi a cikin sashi na 145 MG (Allunan 20).

Wadannan magunguna masu zuwa na analogues na Traicor:

An ba da izinin amfani da analogues kawai bayan tuntuɓar likita da zaɓin sashi mai mahimmanci.

Bugu da kari, wannan magani yana da kwatankwacinsa. Yana da Lipantil 200M, Fitowa, Canjin Fenofibrat.

Binciken janar gaba daya game da amfanin amfani da Tricor ya zama ya hade. Wasu likitoci, lokacin da suke rubuta wannan magani, suna lura da ingantacciyar hanyar ci gaba a cikin bayanin martabar lipid.

Sauran likitoci da marasa lafiya suna tilasta yin watsi da amfani da wannan magani, tunda tasirinsa ya rinjayi kyakkyawan sakamako na amfani.

Ko ta yaya Kuna iya amfani da Tricor don magani kawai bayan tuntuɓarku da likitanka da gwajin koda da hanta. A wannan yanayin, idan ba a sami haɗarin da ke haifar da lalacewa a cikin lafiyar mai haƙuri ba, yana yiwuwa a ɗauki waɗannan kwayoyin.

Binciken da aka yi game da miyagun ƙwayoyi bai ƙunshi kowane bayani ba game da canje-canje a cikin lafiyar mutum yayin tuki.

  • An ƙaddara tricor don maganin hyperlipoproteinemia, wanda ba za'a iya daidaita shi da abinci ba.
  • Yi amfani da magani kawai kamar yadda likita ya umurce ka.
  • Ana amfani da maganin gaba daya a ciki, ba tare da la'akari da lokacin cin abinci ba (banda ɗaukar allunan a sashi na 160 MG).
  • Tricor yana contraindicated a lokacin daukar ciki da kuma lactation, hanta da koda dysfunctions, tashin hankali ga aka gyara daga cikin miyagun ƙwayoyi, kuma shi ne ba da shawarar ga yara.
  • Magungunan yana da yawan adadin sakamako masu illa.
  • Anyi taka tsantsan don amfani da Tricor tare da wasu magunguna.

Shin labarin ya taimaka muku? Wataƙila ita ma zata taimaka wa abokanka! Da fatan za a danna ɗaya daga cikin maɓallin:

Tsarin maganin ƙwaƙwalwar ƙwayar cuta - umarnin amfani

Ofayan magungunan agaji da ake amfani da su a cikin cututtukan ƙwayar cuta shine Tricor. Bai yi amfani da magungunan hypoglycemic ba, amma yana iya ɗan rage matakin glucose a cikin jini.

Don fahimtar yadda ake amfani da shi daidai, kuna buƙatar gano babban yankin aikace-aikacensa da kuma manyan halaye.

Bayani na gaba daya, abun da ya shafi da kuma sakin saki

Dangane da radar, Tricor magani ne mai rage karfin jiki - daga cholesterol a cikin jini. Amfani da shi yana taimakawa rage yawan kitse a jiki kuma yana hana samuwar atherosclerosis.

Fitar tasa an yi ta ne a Faransa, inda ake siyar da wannan magani ta hanyar allunan. Sakamakon maganin yana faruwa ne saboda babban bangaren, wanda shine fenofibrate.

Kuna iya amfani dashi kawai kamar yadda likita ya umarta, tunda yana da tasiri mai ƙarfi akan jiki. Wataƙila rashin daidaituwa na rikice-rikice idan an cinye ta ba lallai ba. Sabili da haka, yana yiwuwa a saya kawai ta takardar sayan magani.

Ana aiwatar da samar da kudade a cikin allunan. Babban sinadaran aiki na maganin shine fenofibrate. An haɗa shi a cikin allunan a cikin adadin 145 MG.

Baya ga shi, akwai abubuwa irinsu:

  • yi nasara
  • sabbinne,
  • sodium docusate,
  • sitiri na magnesium,
  • microcrystalline cellulose,
  • lactose monohydrate,
  • sodium laurisulfate,
  • silikion dioxide colloidal.

Wadannan abubuwa suna ba ka damar ba da maganin yadda ake so. Allunan an rufe fim ɗin (bp).

Hakanan akwai Allunan tare da kayan aiki mai aiki na 160 MG. Sun ƙunshi ƙarin kayan haɗin guda ɗaya kamar wani nau'in magani.

Kunshin magunguna suna da jeri daban-daban. Zasu iya haɗawa daga 10 zuwa 300 Allunan (sashi na 145 mg) ko daga 10 zuwa 100 guda (kashi na 160 mg).

Aikin magunguna da magunguna

Don fahimtar abin da ake nufi da wannan maganin, kuna buƙatar gano fasalin aikinsa.

Fenofibrate yana da tasiri kan triglycerides, rage adadin su. Hakanan yana taimakawa rage cholesterol a cikin jini. Wannan ya faru ne sakamakon cin zarafin mai mai.

Yin amfani da miyagun ƙwayoyi na iya rage adadin fibrinogen. Slightlyungiyar mai rauni mai rauni mai ƙarfi yana aiki akan glucose, yana taimakawa rage matakinsa. Wadannan sifofi suna sa Tricor yayi tasiri don lura da marasa lafiyar atherosclerosis wadanda ke da muradin bunkasa ciwon sukari.

Fenofibrate ya kai ƙarshen tasirin sa'o'i 5 bayan gudanarwa (wannan yana tasiri da halayen kayan jikin mutum).

Significantarancin sa yana ɗaure wa albumin, furotin plasma, samar da fenofibroic acid. Ana amfani da metabolism dinsa a cikin hanta. Abubuwan yana da tasirin gaske - kusan awanni 20 ana buƙatar cire rabin shi. Yana barin jiki ta hanjin ciki da kodan.

Manuniya da contraindications

Kuna iya gano abin da wannan kayan aiki ke taimaka daga ta hanyar nazarin umarnin da alamomi don dalilin sa.

An ba da shawarar yin amfani da shi don wannan take hakki kamar:

  • basantankara,
  • sabar, kamar,
  • hyperlipoproteinemia.

Tare da irin waɗannan cututtukan, ana amfani da Tricorr idan hanyoyin rashin magani ba su kawo sakamako ba.

Hakanan, likita na iya ba da wannan magani don shawo kan wasu cututtuka a matsayin wani ɓangare na maganin rikice-rikice, idan irin waɗannan ayyukan sun dace.

Dole ne a tuna cewa kasancewar alamomi don takardar sayen magani ba ya nufin yin amfani da wannan magani. Gano magungunan hana tilastawa yin watsi da amfani da ita.

Wadannan sun hada da:

  • mummunan cutar hanta
  • mummunan matsalolin koda
  • rashin haƙuri a cikin abun da ke ciki,
  • lactation
  • cutar hanji
  • shekarun yara.

Haka kuma akwai lokuta inda aka yarda da amfani da Tricor, amma yana buƙatar ƙarin taka tsantsan:

  • barasa
  • hawan jini
  • tsufa
  • take hakki a hanta da kodan.

Wannan yana nufin cewa zaku iya shan wannan magani kawai kamar yadda kwararrun likitoci suka umurce ku. Yin magani na kai na iya haifar da rikitarwa.

Marasa lafiya na musamman da kuma Jagorori

Yawan marasa lafiya don waɗanda aka ba da shawarar ta musamman lokacin amfani da Tricor an haɗa su da rukuni na mutane:

  1. Mata yayin daukar ciki. Aiki abu na miyagun ƙwayoyi ne contraindicated, saboda haka, da amfani da shi an haramta a wannan lokacin.
  2. Iyayen mata masu shayarwa. Sakamakon fenofibrate akan ingancin madara mai nono da kuma akan jariri ba'a kafa shi ba.A wannan batun, likitoci ba sa amfani da Trikor don irin waɗannan marasa lafiya.
  3. Yara. A karkashin shekara 18, ba a yi amfani da wannan magani ba, saboda ba a san yadda saitinsa zai iya shafar jikin yara ba.
  4. Tsofaffi mutane. Don wannan rukuni na marasa lafiya, ana amfani da maganin yana da karɓa. Amma kafin alƙawarin sa, marasa lafiya suna buƙatar jarrabawa don guje wa rikice-rikice masu yiwuwa. Hakanan ana rage rage sashi.

Sauran mutane (in babu contraindications) na iya amfani da maganin kamar yadda likita ya umarta.

Dole ne a yi taka tsantsan yayin amfani da Traicor a gaban waɗannan raunin da ke cikin jiki:

  1. Cutar koda. A cikin mummunan cututtuka na wannan sashin, an haramta amfani da miyagun ƙwayoyi. Deviarancin karkacewa a cikin aikin kodan suna buƙatar kulawa da kulawa akai-akai game da aikin jiyya tare da amfani.
  2. Cutar hanta. Don ƙananan matsalolin hanta, likita zai iya ba da maganin Tricor bayan jarrabawa. Violationsayyadaddun ƙetare dalilai ne na ƙin shan miyagun ƙwayoyi.

Fenofibrate na iya shafar aikin hanta, don haka koda a cikin rashin damuwa a wannan yankin, kuna buƙatar duba yanayin shi lokaci-lokaci. Hakanan, a ƙarƙashin rinjayar miyagun ƙwayoyi, sigogin coagulation na jini na iya canzawa - wannan kuma yana buƙatar sarrafawa.

Hadin gwiwar Magunguna da Analogs

Gwanin ƙwaƙwalwar ƙwaƙwalwa ya ƙunshi haɗuwa daidai na magungunan da aka yi amfani da su. Idan magani daya ya gurbata tasirin wani, sakamakon zai iya zama wanda ba zai yiwu ba. Sabili da haka, kuna buƙatar yin la'akari da yadda Tricor zai iya shafar waɗancan magungunan da ake amfani da su a layi ɗaya da shi.

Tsanani yana buƙatar haɗuwa da wannan magani tare da:

  • magungunan anticoagulants (fenofibrate suna ƙoƙarin inganta tasirin su, wanda ke haifar da haɗarin zubar jini),
  • Cyclosporine (ana iya lalata aikin koda),
  • statins (akwai haɗarin cutarwa mai guba a kan tsokoki).

Don wasu kwayoyi, ba a lura da canje-canje masu mahimmanci ba. Koyaya, mai haƙuri dole ne ya sanar da likita game da duk magungunan da yake amfani da shi don ƙwararren likita ya iya ba da cikakkiyar magani.

Dalilan yin amfani da kayan aikin analog na iya bambanta. Mafi sau da yawa, marasa lafiya suna neman analogues mai rahusa, tunda ɗaukar magani mai tsada akan ci gaba mai gudana aiki ne mai tsada sosai.

Wasu kuma suna damuwa da illolin da ke haifar musu da wahala su yi aiki cikakke. A wannan batun, kwararru galibi suna buƙatar zaɓar kwayoyi tare da tasirin irin wannan.

Wadannan sun hada da:

Wasu daga cikin kudaden da aka lissafa suna da kayan kama da na Traicor. Ga waɗansu, tasirin kama ɗaya halayen ne, duk da bambance-bambance a cikin kayan haɗin.

Don amfani da analog, dole ne ka nemi likitanka. Kai magani kai koyaushe yana da haɗari, saboda haka kana buƙatar tabbatar da cewa zaɓaɓɓen magani ya dace da wani mai haƙuri.

Mai haƙuri ra'ayi

Abun sake dubawa game da kwayar Tricor galibi tabbatacce ne - da yawa suna lura da fa'idarsa mai amfani ga jiki da rage ƙwaƙwalwar jini.

Kudin maganin yana dogara ne akan sashi na sashi mai aiki wanda yake kunshe da adadin allunan a cikin kunshin. Don kayan haɗi tare da allunan 30 (145 MG) kana buƙatar ba daga 750 zuwa 900 rubles. A sashi na 160 MG da irin kayan marufi iri ɗaya, farashin Tricor zai kasance daga 850 zuwa 1100 rubles.

Muna bada shawara ga wasu labaran masu alaƙa

Tricorrh: umarnin don amfani, farashi, sake dubawa, analogues »

Tricor magani ne na mai ƙirar Faransa. Dangane da umarnin don amfani, an yi nufin ne don magance cututtukan cututtukan zuciya.

Ta ƙunshi rukunin magungunan rage ƙwayar lipid, wanda kuma ake kira fibrates. Wannan sunan yana nuna tsarin aiki - fenofibrate.

Magungunan yana nufin abubuwan da aka samo daga fibroic acid.

Aikace-aikacen

A cikin aikin likita, ana amfani da Tricor don kula da waɗannan cututtukan:

  • hypercholesterolemia da hypertriglyceridemia, duka biyu ya zama ruwan dare da gauraye (nau'ikan daban daban na dyslipidemia) a cikin marassa lafiya ga wanda abincin ko wasu hanyoyin magani na rashin magani ba su da inganci (matakan da ke nufin asarar nauyi, ƙara yawan aiki na jiki). Wannan yana da mahimmanci musamman ga lokuta idan akwai abubuwan haɗari kamar halaye mara kyau (shan sigari) da hauhawar jini,
  • sakandare hyperlipoproteinemia lokacin da alamunta suka ci gaba duk da tasirin magani ga cutar rashin lafiyar (misali, dyslipidemia a cikin ciwon sukari mellitus).

Sakin Fom

A cikin samar da magunguna, ana samun magungunan a cikin nau'ikan allunan guda biyu, wadanda suka bambanta da adadin kayan aiki mai aiki (fenofibrate), wanda yake a cikin adadin 145 mg (micronized), ko 160 mg.

Wadanda suka kware sune sucrose, sodium lauryl sulfate, lactose monohydrate, crospovidone, colloidal silicon dioxide, da sauransu.

Allunan suna da sifo mai kama da juna, an rufe su da farin fim fim. Ana sanya tambarin a gefe ɗaya, lambobi a gefe guda kuma suna nuna adadin babban abu a cikin abin da aka tsara samfurin (145 ko 160).

Allunan an sanya su cikin blisters na guda 10. Kunshin kwali na iya ƙunsar daga 1 zuwa 10 murhun.

Yarbuwa

Yin amfani da Tricor lokaci guda tare da wakilai na hypoglycemic waɗanda keɓaɓɓe na sulfonylureas na iya haifar da karuwa a cikin tasirin hypoglycemic.

Haɗin Tricor tare da maganin rashin daidaituwa (ciki har da acenocoumarol, warfarin) yana inganta tasirin ƙarshen.

Akwai hasashe game da mahimmancin aikin fibrates wajen kara kusancin anticoagulants ga wasu masu karɓa, kazalika da keta al'aurar su.

Haɗin wannan miyagun ƙwayoyi tare da cyclosporine na iya haifar da aiki na keɓaɓɓen aiki da haɓaka taro na wannan abu a cikin jini.

Yawan abin sama da ya kamata

Ba a bayyana alamun halayen ƙarin yawan maye lokacin shan Traicor ta hanyar littattafan likitanci. Hakanan, ba a kafa takamaiman maganin rigakafi ba. Idan akwai shakku game da yawan abin sama da ya kamata, alamomin cutar kuma, idan ya cancanta, ya kamata a rubuta maganin kulawa. An ƙaddara cewa hemodialysis ba su da tasiri.

Nina P. a cikin bita http://otzovik.com/review_2302884.html yana lura da tasiri na miyagun ƙwayoyi, musamman mahimmancinta don rage ƙwaƙwalwar ƙwayar.

Koyaya, ta yi gargadi game da shan kai, yana jaddada buƙatar kula da kwararru a koyaushe yayin aikin warkewa. Marubucin ya kuma nuna yiwuwar mummunan tasirin sakamako yayin jiyya tare da Tricor.

Don haka ita kanta ta sami halittar gallstones. A saboda wannan dalili, matar ta ki yin karatun ta biyu kuma tana ganin ya wajaba a yi mata gwajin cutar hanji.

An sayi maganin ne gwargwadon maganin likita wanda ya duba sakamakon gwajin a kai a kai don tabbatar da rashin sakamako masu illa.

Elena K. a cikin bita https://health.mail.ru/drug/tricor/ ta rubuta cewa wannan magani bai dace da ita ba. Ta sha shi tsawon watanni biyu kuma ta ji ciwo mai zafi a cikin paresis na jiki, da kuma rauni na tsoka gaba ɗaya. Hakanan ba ta lura da cigaba ba, saboda wannan dalilin ba ta ba da shawarar Tricor don amfani.

Alexey P. a cikin bita https://health.mail.ru/drug/tricor/ ya rubuta cewa ya ɗauki Tricor fiye da watanni 4. A wannan lokacin, jin zafi a kafafu ya ragu, kuma lafiyar ta zama mafi kyau.

Tricor magani ne wanda aka yi a Faransa. Amfani da maganin cututtukan cututtukan zuciya. A matsayin wakili mai saurin rage yawan sinadarai, Tricor nasa ne na fibrates.

Ana amfani dashi da ƙarfi don ƙaddarar da ya yi daidai da umarnin, kan shawarwarin kuma a ƙarƙashin kulawar likita. Akwai da yawa contraindications da sakamako masu illa. Lokacin shan wannan magani, ya kamata a kula da yawan maganin da aka nuna.

Bai dace da mata masu juna biyu da masu shayarwa ba, harma da yara.

Adana ko raba:

Tricor: analogues ne kawai mai rahusa, umarnin don amfani, farashi, bita

Tricor- Ana amfani da wannan magani don ciwon sukari da dyslipidemia. Yana da halayyar cututtukan ƙwayar cuta.

Hanyar aikin:

  • Yana kunna RAPP-alpha, wanda ke haifar da ƙaruwa da lipolysis,
  • Formirƙiri na apoproteins na nau'ikan AI, AII,
  • Yana rage yawan ƙwayoyin atherogenic lipids a cikin ƙwayar plasma saboda yawan tashin hankali,
  • Yana rage adadin kuzari, triglycerides,
  • Yana rage jigilar abubuwa na cholesterol,
  • Yana hana tarawar platelet hade da epinephrine, arachidonic acid da ADP.

Game da kwayoyin marasa tsada don rage cholesterol - sunaye, farashi da bita da muka rubuta anan.

Wani muhimmin fasalin magungunan shine cewa a cikin tsarin jikin mutum yanayin fenofibrate ya kai matsakaicin, ana ganin wannan tasiri riga sa'o'i 2-3 bayan shan kwayoyin. Kayan aiki kuma yana da tasirin uricosuric.

Loaukaka mai ƙarancin Tricor

  • Canjin Fenofibrat. Ya bambanta a cikin jerin magabata. Ana amfani da sitaci na masara, colloidal silicon dioxide, sirinum croscarmellose, mannitol, magnesium stearate, povidone K-30, microcrystalline cellulose. Ana tunawa da shi da hankali sosai (daga baya ya kai matsayin girmansa cikin jini). Farashin 489 rub.

  • Fitowa - ya bambanta a cikin nau'in saki (kwalliya) da kashi na abu mai aiki (fenofibrate) - 250 MG.
  • Lipantil - ya bambanta da nau'in saki (kwalliya), sashi (200 mg). Bambanci kawai yana cikin abubuwan taimako - gelatin, iron oxide (E172), sitaci gelatinized. Kudin 850 rubles.

    Abubuwa masu aikiFitowa
    Lactose Monohydrate
    Microcrystalline silicatized cellulose
    Sanatari
    Amasamai
    Sodium Lauryl Sulfate
    Shafin Sodium
    magnesium stearate
    OpadriOY-B-28920 (Polyvinyl barasa, dioxide titanium (E 171), talc, soya lecithin, xanthan gum)

    Akwai shi a cikin MG na 145 da allunan 160 MG kuma a cikin fakitoci daban-daban: fakitin kwali daga blister 1 zuwa 30.

    Maganin anticoagulants na baka

    Yana ƙaruwa da tasirin maganin hana daukar ciki, na iya ƙara haɗarin zub da jini. Don guje wa wannan, ana bada shawara don rage kashi na maganin anticoagulants da misalin 1/3 kuma sannu a hankali ya kawo shi ga yarda da MHC (ƙaddarar ƙayyadaddun ƙasashen duniya).

    • Sankarini. An yi rubuce-rubuce da yawa na lokuta masu rauni na lalatattun renal. Dangane da waɗannan shari'o'in, wajibi ne don saka idanu sosai a kan aikin renal a cikin marasa lafiya suna ɗaukar wannan haɗin, kuma idan akwai canje-canje masu haɗari a cikin sigogin dakin gwaje-gwaje, nan da nan daina shan Tricor.

    HMG-CoA reductase hanawa ko wasu fibrates

    Hadarin illa mai guba a cikin tsokoki, ya zama dole a yi amfani da irin wannan haɗuwa tare da taka tsantsan.

    Lokacin ɗaukar Traicor tare da kwayoyi na wannan rukunin, akwai lokuta na raguwa mai mahimmanci a cikin matakin babban yawan lipoproteins mai yawa. Wajibi ne don sarrafa matakan su kuma nan da nan daina amfani da wannan haɗin idan ya rage.

    Enzymes na Cytochrome P450

    Fenofibrates da fenofibroic acid ba sune masu hana cytochrome isoform (CYP) P450 CYP3A4, CYP2D6, CYP2E1 ko CYP1A2. A cikin babban taro na warkewa, sun kasance masu laushi masu matsakaici na matsakaita na CYP2C9 da masu rauni na CYP2C19 da CYP2A6.

    Kulawa sosai da marasa lafiya ke ɗauka fenofibrate da magungunan da CYP2C19, CYP2A6, da kuma musamman CYP2C9, kuma suna da kunkuntar warkewa, ya zama dole.

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