Acekardol: umarnin don amfani, analogues da sake dubawa, farashin a cikin kantin magunguna na Rasha

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Side effects

Dangane da sake dubawa, Acecardol da misalanta na iya haifar da sakamako masu illa:

• Tsarin cututtukan Hematopoietic: anaemia, haɓaka damar zub da jini,
• Tsarin numfashi: zuciya,
• Allergies: urticaria, fitsari a kan fata, itching, edema ta Quincke, bugun zuciya da jijiyoyin jiki, kumburin hanci, hancin hanci, tashin hankali,
• Tsarin juyayi na tsakiya: asarar ji, tinnitus, dizziness, ciwon kai Tsarin narkewa: ciwon ciki, ƙwannafi, tashin zuciya, matsananciyar ciki, ƙonewar hanji da haɓaka, haɓaka aikin hanta enzymes.

Abun da yakamata ba zai yuwu ba, tunda abu mai aiki, acetylsalicylic acid, yana cikin ƙananan adadi. Yawan wuce haddi na ASA na iya haifar da zub da jini na ciki.

Haihuwa da lactation

Cutar ciki da lactation sune manyan abubuwanda suka sabawa amfani da miyagun ƙwayoyi Acekardol. An haramta wakilin rigakafin a cikin watanni na 1 da na uku na ciki, a cikin sati na biyu da za a dauka tare da taka tsantsan kuma kamar yadda likita ya umurce shi. Shiga cikin sati na biyu yana da kyau kawai a kan sharadin cewa amfanin magani ga mahaifiya ya wuce barazanar tayin.

Analogs na Acecardol

Tsarin analogues na mai aiki abu:

• Manda,
• ASK-cardio,
• Asficore
• Aspinat
• Asfirin York
• Asfirin
• Asfirin 1000
• Asfirin Cardio,
• Asfirin Express,
• Acenterin,
• Acetylsalicylic acid
• Acyliptrin,
• Atsbirin,
• Bufferin
• CardiASK,
• Cardiomagnyl
• Colpharite
• Mikristin
• Plidol 100,
• Plidol 300,
• Harshen Polokard,
• Taspir
• Thrombo ACC,
• Thrombogard 100,
• Yaron
• Walsh Asalgin,
• Upsarin UPSA,
• HSN Payne.

Hankali: amfani da maganin analogues yakamata a yarda da likitan halartar.

Matsakaicin farashin ATSECARDOL, allunan a cikin kantin magani (Moscow) shine 25 rubles.

Formaddamar da tsari da abun da ke ciki

Acecardol an samar dashi a cikin nau'ikan allunan biconvex zagaye, mai rufi tare da farin harsashi.

Kwamfutar hannu 1 ya ƙunshi:

• Abunda yake aiki: Acetylsalicylic acid (ASA) - 50, 100 ko 300 MG,
• Abubuwa masu taimako: lactose, titanium dioxide, magnesium stearate, castor oil, microcrystalline cellulose, povidone, sitaci masara.

Side effects

Koyarwar tayi kashedin game da yiwuwar bunkasa wadannan sakamako masu illa yayin rubuta Acekardol:

• A wani bangare na tsarin numfashi: bronchospasm,
• Daga gefen tsarin juyayi na tsakiya: tinnitus, asarar ji, rashi, ciwon kai,
• Daga tsarin hawan jini: hawan jini, haɓakar damar zub da jini,
• Daga narkewa kamar jijiyoyi: ƙwannafi, amai, tashin zuciya, ciwan ciki, hanji na ciki, ƙonewar hanji, aikin hanta mai rauni,
• Allergic halayen: fata itch, fatar, urticaria, rhinitis, Quincke ta edema, anaphylactic gigice.

Contraindications

Acekardol yana cikin abubuwan da ke tafe:

• na kullum zuciya
• mai girma na koda da hepatic gazawar,
• exacerbation na erosive da ulcerative raunuka na gastrointestinal fili,
• basur na jini,
• na ciki,
• hypersensitivity to acetylsalicylic acid,
• asma,
• karancin maganin lactase, karancin glucu-galactose malabsorption, rashin maganin lactose,
• shan methotrexate a cikin mako-mako na 15 MG ko fiye, a lokacin daukar ciki da lactation, a karkashin shekaru 18.

Sanya tare da taka tsantsan lokacin da:

• koda mai aiki da hanta,
• hawan jini, gout,
• Tarihin cututtukan ciki da na ciki
• cututtuka na numfashi na yau da kullun, polyposis hanci, zazzabin hay, ƙwayoyin cuta,
• conticitagic anticoagulant far,
• shan methotrexate a sati na sati daya wanda bai wuce 15 MG ba, a cikin sati na biyu na ciki kuma kafin a fara ayyukan tiyata (gami da kanana).

Yawan abin sama da ya kamata

Symptomsaukar bayyanar cututtuka sun haɗa da tsananin damuwa, tashin zuciya, ciwon kai, rikicewa, tinnitus, ɗaci mai yawa, tachypnea, da hauhawar jini.

Nagari mai amfani na ciki, amfani da carbon da aka kunna da kuma daidaita ma'aunin ruwa-electrolyte.

Tare da mummunan yawan abin sama da ya kamata, zai yiwu - zafin jiki sosai, tashin zuciya, tashin zuciya, tsarin jijiyoyin jiki, hawan jini, zubar jini a ciki da hanji.

A wannan yanayin, ana buƙatar asibiti mai gaggawa da magani na gaggawa, ciki har da wankewar gastrointestinal, sake amfani da carbon mai kunnawa, hemodialysis, tilasta alkaline diuresis, maido da yanayin acid-base da ma'aunin ruwa-electrolyte, kazalika da alƙawarin maganin cututtukan alamomi da nufin kawar da ci gaban ci gaba. take hakki.

Umarni na musamman

Acekardol na iya tayar da jijiyoyin jiki da ciwon asma. Abubuwan haɗari: tarihin ƙwayar hanci, hanci, ƙwayar cuta, ƙwayar mahaifa.

Sakamakon da aka samu na hana tara platelet din ya ci gaba na wasu kwanaki, wanda zai haifar da zubar jini yayin ayyukan tiyata na gaggawa. Kafin a fara aiki, ana soke maganin aƙalla kwanaki 7 a gaba.

A cikin marassa lafiyar mai rauni, Acecardol a cikin kananan allurai na iya haifar da gout. A hadarin sune waɗanda ke da ragewar uric acid excretion.

Tare da karuwa a cikin adadin ƙwayoyi, haɗarin zub da jini na narkewa yana ƙaruwa sosai.

Ba ya tasiri da ikon tuki. A cikin lura da glucocorticosteroids, dole ne a ɗauka a zuciya cewa tare da sakewarsu, ƙarin yawan adadin salicylates yana yiwuwa.

Haɗa kai

Cutar Acecardol tana inganta yawan guba na methotrexate, yana rage haɓakar ɗanyenta, sinadarin valproic. Yana haɓaka tasirin sauran NSAIDs, narcotic analgesics, na baki hypoglycemic magunguna, heparin, kai tsaye anticoagulants, thrombolytics da antiplatelet jamiái, sulfonamides (gami da co-trimoxazole), T3. Yana rage tasirin magungunan uricosuric (benzbromarone, sulfinpyrazone), magungunan antihypertensive, diuretics (spironolactone, furosemide).

Magungunan GCS, ethanol da ethanol dauke da kwayoyi suna haɓaka sakamako mai lahani ga mucosa, haɓaka haɗarin zub da jini na ciki.

Theara yawan taro da digoxin, barbiturates, da kuma giyar Li + a cikin ƙwayar plasma.

Antacids masu dauke da Mg2 + da / ko Al3 + suna ragewa kuma suna rage yawan shan ASA.

Magungunan Myelotoxic suna haɓaka bayyanuwar ƙwayar hematotoxicity na miyagun ƙwayoyi.

Acecardol, umarnin don amfani (Hanyar da sashi)

Ana bada shawarar magani don sha kafin abinci. Yana da kyau a sha Allunan tare da isasshen ƙwayar ruwa. An wajabta magunguna na dogon lokaci. Maimaitawa da yawa - sau 1 a rana.

Idan ana zargin infarction myocardial m don rigakafin sanya 100 MG kowace rana ko 300 MG kowace rana. Allunan cinya suna ba da sakamako mai sauri, wanda yake da mahimmanci a cikin farkon farkon fitowar myocardial infarction. Idan akwai abubuwan haɗari da yawa lokaci ɗaya, 300 MG kowace rana, ko 100 MG kowace rana, an wajabta don rigakafin matsanancin ƙwayar cuta na cikin zuciya.

Yin rigakafin cutar angina pectoris, mai saurin kamuwa da zuciya, rigakafin cutar sankara a jiki, ischemic bugun jini: 100-300 MG kowace rana.

Don rigakafin cututtukan hanji na hanji, ƙwaƙwalwar ƙwayar jijiya mai zurfi sanya 300 MG kowace rana, ko 100 MG kowace rana.

Yawan abin sama da ya kamata

Alamun sassauci kamar suma, tashin zuciya, ciwon kai, rikicewa, tinnitus, yawan shan ruwa, tachypnea, da hauhawar jini zai yiwu. A wannan yanayin, magani zai ƙunshi lalacewa na ciki, babban amfani da carbon wanda aka kunna, da kuma sake dawo da ma'aunin ruwa da lantarki.

Tare da tsananin tsananin zafin jiki, zai yiwu: zafin jiki sosai, tashin zuciya, tashin zuciya, tsarin jijiyoyin jini, zubar jini a ciki da hanji. Kuma a wannan yanayin asibiti mai gaggawa ya zama dole.

Pharmacokinetics

Bayan gudanar da baki, ASA yana cikin sauri kuma yana ɗauka daga cikin jijiyoyin jiki, a yayin da yake ƙarƙashi. A lokacin da bayan sha, ASA ya juya zuwa babban metabolite - salicylic acid, wanda aka metabolized galibi a cikin hanta (a ƙarƙashin rinjayar enzymes) don samar da metabolites kamar salicylic acid, salicylic acid glucuronide da phenyl salicylate. An samo su a cikin kyallen takarda da fitsari da yawa. A cikin mata, tsarin metabolism ya yi hankali fiye da na maza.

Bayan ɗaukar Acecardol a ciki, ana lura da mafi girman maida hankali na ASA a cikin jini jini bayan minti 10-20, salicylic acid - bayan awanni 0.3-2.

Allunan Acecardol an lullube su da wani sinadari mai tsaurin acid, wanda ke hana miyagun ƙwayoyi narkewa a cikin ciki, don haka ana sakin abu mai aiki a cikin yanayin alkaline na duodenum. A wannan batun, ɗaukar ASA shine sa'o'i 3-6 a hankali fiye da lokacin ɗaukar allunan al'ada (ba a haɗa shi da irin wannan harsashi).

Acetylsalicylic da salicylic acid suna daure wa furotin na plasma (gwargwadon sashin, wannan mai nuna shine 66 - 98%) kuma an rarraba shi cikin sauri. Acid na Salicylic ya ratsa cikin mahaifa har zuwa cikin nono.

Metabolism of salicylic acid yana iyakance ta ƙarfin tsarin enzymatic, sabili da haka, ƙwayar kansa ta dogara ne da kashi-kashi.Rabin rayuwar yana kasancewa daga awanni 2-3 (a cikin yanayin allurai) zuwa awanni 15 (lokacin amfani da manyan allurai azaman antipyretic da analgesic).

Tare da tsawaita amfani, ASA mara ruwa mai narkewa ba ya tarawa cikin tarawar jini, sabanin sauran salicylates.

Kwakwalwar Salicylic da metabolites din ta ke cirewa ta kodan. Tare da aikin koda na al'ada, daga 80 zuwa 100% na kashi ɗaya na ASA an keɓe shi cikin awa 24-72.

Sashi da gudanarwa

Ana ɗaukar allunan Acecardol a baki kafin abinci, ana wanka da ruwa. Magungunan an yi niyya ne don tsawan amfani da shi.

Idan ana zargin infarction na myocardial, ana ɗaukar Acecardol 100 MG sau ɗaya a rana ko 300 MG kowace rana. Don ingantaccen tasirin warkewa, ana iya ƙwarar da kwamfutar hannu ta farko.

Don hana infarction na myocardial na maimaitawa, rufewar hanji da kuma rassanta tare da jini, zurfin jijiyoyin jini kuma tare da angina mai tsayayye, ana daukar Acecardol 100-300 mg kowace rana.

Don hana ƙwayoyin thromboembolism bayan abubuwan haɗari da tiyata, sashi na Acecardol shine 100-300 MG kowace rana.

Haihuwa da lactation

A cikin farkon farkon lokacin ciki, salicylates a cikin manyan allurai suna kara hadarin haifar da lahani a cikin tayin (raunin palate, lahani na zuciya), don haka Acecardol ya zama mai cikakken kariya don amfani.

A cikin kashi biyu na ciki na ciki, ana iya ba da magunguna kawai idan amfanin da ake tsammanin ya fi ƙarfin haɗari. A lokaci guda, ana bada shawara don amfani da Acecardol a allurai ba fiye da 150 MG don mafi taƙaitaccen karatun ba.

A cikin kashi uku na ciki na ciki, salicylates a cikin allurai masu yawa (fiye da 300 mg / rana) yana raunana aiki, haifar da karuwar zubar jini a cikin mahaifiya da tayin, da kuma rufewa da tsufutuwa na mahaifa a cikin tayin. Shan ASA nan da nan kafin haihuwa na iya haifar da zubar jini a cikin mahaifa, musamman a cikin jarirai. Game da wannan, a cikin ƙarshen sati na ƙarshe na ciki, Acecardol yana da matukar ƙarfi don yin amfani da shi.

Salicylates da metabolites dinsu sun shiga cikin madarar nono, wanda shine dalilin da ya sa aka sa Acecardol a cikin mata masu shayarwa. Idan shan magani ya zama karbuwa a asibiti, ya kamata a daina shayar da jarirai.

Hulɗa da ƙwayoyi

Game da yin amfani da lokaci ɗaya, acetylsalicylic acid yana raunana aikin waɗannan kwayoyi masu zuwa: diuretics, inhibitors na angiotensin-mai sauya enzyme (ACE), magungunan uricosuric (benzbromarone).

Game da amfani da lokaci daya, acetylsalicylic acid yana haɓaka aikin da kwayoyi masu zuwa: jami'in antiplatelet da magungunan thrombolytic, digoxin, heparin da magungunan anticoagulants na kaikaice, methotrexate, valproic acid, magungunan hypoglycemic (insulin da kalamai na sulfonylurea).

Hakanan, haɗuwa da ASA tare da methotrexate yana da alaƙa da haɓakar haɗarin halayen haɗari daga gabobin hemopoietic, tare da thrombolytics, wakilai na antiplatelet da maganin anticoagulants - haɓakar haɗarin zubar jini.

ASA yana inganta tasirin cutar ethanol akan tsarin juyayi na tsakiya. Wannan yana kara yiwuwar lalacewar cikin mucous membrane na hanji da na lokaci mai tsawo.

Tsarin glucocorticosteroids yana inganta kawar da miyagun ƙwayoyi, fiye da raunana tasirinsa.

Tsarin analogues na Acecardol sune shirye-shiryen Thrombo ACC, Aspirin, Cardiopyrine, Aspinat, Aspicor, Taspir, Thrombopol, Acetylsalicylic acid.

Ra'ayoyi akan Acecardol

Dangane da sake dubawa, Acekardol shine wakili mai amfani na antiplatelet wanda ke narke jini kuma yana hana thrombosis. Additionalarin nasa fa'idodi sun haɗa da ƙarancin farashi (idan aka kwatanta da yawancin analogues), sauƙi na gudanarwa (lokaci 1 a kowace rana), nau'in sashi (kayan shigar ciki yana kiyaye ciki daga cutarwa na acetylsalicylic acid), kazalika da kasancewar ƙwayoyi daban-daban na allunan (50, 100 da 300 MG), wanda ke ba ka damar zaɓar mafi kyau duka.

Rashin daidaituwa na Acecardol ya haɗa da kasancewar contraindications. Koyaya, suna samuwa don duk abubuwan salicylates, don haka likita ya kamata ya ba da magani.