AKTRAPID NM PENFILL (ACTRAPID HM PENFILL) umarnin don amfani
Type 1 ciwon sukari mellitus, type 2 ciwon sukari mellitus: mataki na jure wa baki hypoglycemic magunguna, m jure na baka hypoglycemic magunguna (hade far),
ketoacidosis mai ciwon sukari, ketoacidotic da hyperosmolar coma, ciwon sukari wanda ya faru a lokacin daukar ciki (idan maganin rashin abinci ya zama mai inganci),
don amfani na wucin gadi a cikin marasa lafiya tare da ciwon sukari na mellitus a cikin cututtuka tare da zazzabi mai zafi, tare da ayyukan tiyata mai zuwa, raunin da ya faru, haihuwa, cuta na rayuwa, kafin sauya sheka zuwa jiyya tare da shirye-shiryen insulin tsawan lokaci.
Tsarin saki, abun da aka shirya da marufi
Maganin maganin allura abu ne mara kyau, mara launi.
| 1 ml | |
| insulin abinci mai narkewa (injin ɗan adam) | 100 IU * |
Fitowa: zinc chloride, glycerol, metacresol, hydrochloric acid da / ko sodium hydroxide bayani (don kula da pH), ruwa d / i.
* 1 IU yayi daidai da μg na 35 na insulin na mutum.
3 ml - gilashin gilashi (5) - fakitoci na kwali.
Aikin magunguna
Actrapid ® NM shiri ne na insulin da ke yin gajeren zango wanda kwayoyin halittun DNA suka sake amfani da su ta hanyar amfani da kwayar cutar Saccharomyces. Raguwar matakin glucose a cikin jini na faruwa ne sakamakon haɓaka jigilar kwayoyin halittar jikinta bayan ɗaukar nauyin insulin ga masu karɓar ƙwayar tsoka da kyallen takaddar adipose da kuma raguwa a lokaci guda na yawan samarwar glucose ta hanta. Normalization na plasma glucose maida hankali (har zuwa 4.4-6.1 mmol / l) ta iv gudanar da Actrapid ® NM a cikin kulawa mai zurfi wanda ya shiga mummunan aikin tiyata (204 marasa lafiya da masu ciwon sukari da kuma marasa lafiya na 1344 ba tare da mellitus na ciwon sukari ba) waɗanda ke da hyperglycemia (plasma glucose taro> 10 mmol / L), rage mace-mace ta hanyar 42% (4.6% maimakon 8%).
Ayyukan miyagun ƙwayoyi Actrapid ® NM yana farawa a tsakanin rabin sa'a bayan gudanarwa, kuma mafi girman tasirin yana bayyana a tsakanin awanni 1.5-3.5, yayin jimlar aikin shine kusan 7-8 hours.
Bayanai na Tsare na Haraji
A cikin karatuttukan da suka dace, gami da karatun aminci na kimiyyar magunguna, karatuttukan abubuwa masu guba tare da maimaituwa, nazarin ilimin kwayoyin halitta, damar cutar sankara da sakamako masu guba a fagen haihuwa, ba a gano takamaiman hadarin ga bil adama ba.
Pharmacokinetics
T 1/2 na insulin daga cikin jini yan 'yan mintuna ne.
Tsawon lokacin aiwatar da shirye-shiryen insulin shine mafi yawanci saboda yawan sha, wanda ya dogara da dalilai da yawa (alal misali, kan yawan insulin, hanyar da wurin gudanarwa, kauri daga cikin yawan kitse mai cutarwa da nau'in ciwon sukari mellitus). Saboda haka, ma'aunin insulin na insulin na insulin ya shafi mahimmancin yanayin ciki-da na ciki-mutum.
C max na insulin a cikin plasma ana samun shi ne tsakanin awanni 1.5-2.5 bayan kammalawar sc.
Babu wata ma'anar da aka ambata ta danganta ga furotin na plasma da aka ambata, banda abubuwan rigakafi zuwa insulin (idan akwai).
An cire insulin na mutum ta hanyar insulinase ko insulin-inshin-share insulin, kuma wataƙila ta hanyar disproide isomerase.
Ana zaton cewa a cikin kwayar halittar insulin na mutum akwai wurare da yawa na share-fage (hydrolysis), amma, babu wani daga cikin metabolites da aka kirkira sakamakon tsinkewar aiki.
T 1/2 an ƙaddara shi da ƙimar ɗimbin yawa daga ƙwaƙwalwar ƙasa. Don haka, T 1/2 shine mafi kusantar ma'aunin sha, maimakon ainihin matakin cire insulin daga plasma (T 1/2 na insulin daga cikin jini kawai 'yan mintuna). Nazarin ya nuna cewa T 1/2 kusan awa 2-5 ne.
Yara da matasa
An yi nazarin bayanan kantin magani na miyagun ƙwayoyi Actrapid ® NM a cikin karamin rukuni na yara masu fama da cutar sukari (mutane 18) masu shekaru 6-12, da kuma matasa (shekaru 13 zuwa 17). Kodayake bayanan da aka samo suna da iyaka, amma duk da haka sun nuna cewa bayanin kantin magani na Actrapid ® HM a cikin yara da matasa sunyi kama da na manya. A lokaci guda, an bayyana bambance-bambance tsakanin tsararraki daban-daban ta hanyar nuna alama kamar C max, wanda kuma ya sake jaddada bukatar zabin kowane kashi.
Sakawa lokacin
Magungunan an yi shi ne don SC da / a cikin gabatarwar.
An zaɓi kashi na miyagun ƙwayoyi daban-daban, la'akari da bukatun mai haƙuri.
Yawanci, bukatun insulin ya fara daga 0.3 zuwa 1 IU / kg / rana. Bukatar yau da kullun don insulin na iya zama mafi girma a cikin marasa lafiya tare da juriya na insulin (alal misali, a lokacin balaga, har ma a cikin marasa lafiya tare da kiba), da ƙananan cikin marasa lafiya tare da ragowar insulin na insulin.
Ana gudanar da maganin a cikin mintina 30 kafin cin abinci ko abun ciye-ciye wanda ya ƙunshi carbohydrates. Actrapid ® NM insulin aiki ne gajere kuma za'a iya amfani dashi hade da insulins masu aiki da dadewa.
Actrapid ® NM galibi ana yinsa da subcutaneously a cikin yankin bangon ciki na ciki. Idan wannan ya dace, to kuwa za'a iya yin allura a cinya, yankin gluteal ko kuma a cikin yankin na ƙashin kai na kafada. Tare da shigar da miyagun ƙwayoyi a cikin yankin bangon ciki na ciki, ana samun saurin ɗaukar sauri fiye da gabatarwar zuwa wasu yankuna. Idan allurar ta kasance cikin yalwar fata na fata, za a rage girman hadarin da ke tattare da tsarin intramuscular na maganin. Dole ne allurar ta kasance a cikin fata na akalla awanni 6, wanda ke tabbatar da cikakken kashi. Wajibi ne a canza wurin allurar a koyaushe a cikin yankin na jiki don rage haɗarin lipodystrophy. Actrapid ® NM kuma yana yiwuwa a shiga / a ciki kuma irin waɗannan hanyoyin za a iya yin hakan ne ta ƙwararren likita.
A / a cikin gabatarwar miyagun ƙwayoyi Actrapid ® NM Penfill ® daga cikin katun an yarda da shi a matsayin ban da ban da kwalabe. A wannan yanayin, ya kamata ku ɗauki ƙwayar a cikin sirinji na insulin ba tare da ɗaukar iska ba ko kumbura ta amfani da tsarin jiko. Wannan hanyar yakamata kawai likita yayi.
An tsara Actrapid ® NM Penfill ® don amfani da tsarin allurar insulin Novo Nordisk da allurar NovoFine ® ko NovoTvist ®. Cikakken shawarwari don amfani da gudanar da maganin ya kamata a lura.
Cututtukan da ke haɗuwa, musamman masu kamuwa da cuta tare da zazzabi, yawanci suna ƙaruwa da buƙatar jikin mutum na insulin. Hakanan ana iya buƙatar gyaran gyaran jiki idan mai haƙuri yana da cututtukan ƙwayar cuta na koda, hanta, nakasasshen aikin adrenal, pituitary ko glandar thyroid.
Buƙatar daidaitawa na iya faruwa yayin canzawar aiki na zahiri ko abincin da aka saba samu. Zai yiwu a buƙaci daidaitawa yayin canja wurin mai haƙuri daga nau'in insulin zuwa wani.
Side effects
Babban haɗarin haɗari tare da insulin shine hypoglycemia. A lokacin gwaji na asibiti, kazalika a yayin amfani da miyagun ƙwayoyi bayan fitarwarsa a kasuwar mabukaci, an gano cewa yawan abin da ke haifar da ciwon sukari ya bambanta dangane da yawan haƙuri, tsarin yin magani, da kuma matakin sarrafa glycemic.
A matakin farko na maganin insulin, kurakurai masu narkewa, edema da halayen na iya faruwa a wurin allurar (da suka hada da jin zafi, redness, amya, kumburi, kurma, kumburi da itching a wurin allura). Wadannan alamu yawanci ne na wani lokaci. Ingantaccen haɓakawa cikin kulawar glycemic na iya haifar da yanayin "matsanancin raunin neuropathy," wanda yawanci za'a iya juyawa. Intensation na insulin farjin tare da ingantacciyar ci gaba a cikin sarrafa metabolism na metabolism na iya haifar da lalacewa ta ɗan lokaci a cikin yanayin ciwon sukari, yayin da ci gaba na dogon lokaci a cikin kulawar glycemic yana rage haɗarin ci gaban cututtukan ciwon sukari.
Dukkanin sakamako masu illa da aka gabatar a ƙasa, dangane da bayanai daga gwaji na asibiti, an tsara su gwargwadon haɓakar haɓakawa bisa ga tsarin MedDRA da tsarin kwayoyin. Ana bayyana abin da ya haifar da sakamako masu illa kamar:
- sau da yawa (≥ 1/10),
- sau da yawa (≥ 1/100 zuwa Rashin Tsarin Tsarin rigakafi:
- sau da yawa - urticaria, fatar fata,
- da wuya - halayen anaphylactic.
Tsarin cuta na rayuwa da rashin abinci mai gina jiki:
- sau da yawa sau da yawa - hypoglycemia.
Take hakkin tsarin juyayi:
- infrequently - na gefe neuropathy ("m zafi neuropathy").
Arya ta sashin hangen nesa:
- sau da yawa - shakatawa rikice,
- da wuya sosai - maganin ciwon sukari.
Rashin lafiya daga fata da ƙananan kasusuwa:
- sau da yawa - lipodystrophy.
Janar cuta da rikice-rikice a wurin yin allura:
- akai-akai - halayen a wurin allura,
- sau da yawa - edema.
Bayanin raunin halayen mutum ɗaya:
Abubuwan da ke da saurin haifar da yawan tashin hankali (ciki har da fitsari na fata, ƙoshin jiki, yawan zafin jiki, tashin zuciya, ciwon zuciya, raguwar bugun jini, da kasala / asarar hankali, waɗanda ke da haɗari ga rayuwa).
Hypoglycemia shine mafi yawan sakamako masu illa. Zai iya haɓaka idan kashi na insulin yayi yawa sosai dangane da buƙatar insulin. Babban tsananin rashin ƙarfi na iya haifar da asarar da / ko raɗaɗi, wucin gadi ko maye gurbin ayyukan kwakwalwa, ko ma mutuwa. Bayyanar cututtuka na hypoglycemia, a matsayin mai mulkin, yana haɓaka ba zato ba tsammani. Wadannan na iya hadawa da “gumi mai sanyi”, pallor na fata, gajiya mai yawa, tashin hankali ko rawar jiki, damuwa, gajiya mai ban mamaki, ko rauni, rarrabuwa, raguwar hankali, bacci, matsananciyar yunwa, hangen nesa, ciwon kai, tashin zuciya, da saurin kamuwa. bugun zuciya.
An ba da rahoton maganganun marasa galihu na maganin lipodystrophy. Lipodystrophy na iya haɓaka a wurin allurar.
Haihuwa da lactation
Babu ƙuntatawa game da amfani da insulin a lokacin daukar ciki, tunda insulin ba ya ƙetare shingen mahaifa ba.
Dukkanin hypoglycemia da hyperglycemia, wanda zai iya haɓaka cikin yanayin da aka zaɓa na rashin dacewa, yana kara haɗarin rikicewar tayin da mutuwar tayi. Ya kamata a sa ido ga mata masu juna biyu masu ciwon sukari a duk lokacin da suke cikin ciki, yakamata a sami ingantaccen iko na matakan glucose na jini, shawarwari iri daya sun shafi matan da ke shirin daukar ciki.
Bukatar insulin yawanci yana raguwa a farkon farkon ciki kuma sannu a hankali yana ƙaruwa a cikin na biyu da na uku.
Bayan haihuwa, buƙatar insulin, a matsayin mai mulkin, da sauri ya koma matakin da aka lura kafin daukar ciki.
Hakanan babu hani akan amfani da miyagun ƙwayoyi Actrapid ® NM yayin shayarwa. Gudanar da ilimin insulin ga uwaye masu shayarwa ba haɗari ga jariri. Koyaya, mahaifiyar na iya buƙatar sake saita tsarin jigilar Actrapid ® NM da / ko abinci.
Kayan magunguna
Abubuwan da ke aiki a cikin ƙwayar Actrapid Hm Penfill shine insulin ɗan adam mai narkewa. Ana samun wannan abun ta hanyar sarrafa kwayoyin halitta deoxyribonucleic acid. Babban aikin wannan magani, kamar kowane shiri na insulin, shine tsari. Ta hanyar, ragewar glucose din jini yana gudana, haka nan kuma kunna kunnawar glucose ta kashin jiki da tsokawar samarwar glucose ta hanta. Kari akan haka, akwai raguwa a cikin hanyoyin samar da kitse a cikin kitse da kuma kunna hadarin sunadarai. An kafa shi a asibiti cewa rage matakin glucose a cikin jini bayan mai haƙuri ya yi amfani da Actrapid yana farawa tsakanin mintuna talatin na farko. Magungunan ya isa mafi girman tasiri a cikin wani lokaci daga daya zuwa awa uku. Tsawon lokacin aiwatarwa, a matsayin mai mulkin, baya wuce awa takwas. Ya kamata a lura cewa halayen na lokaci-lokaci na iya bambanta dangane da halayen mutum na haƙuri.
Abun ciki da nau'i na saki
Ana amfani da abubuwa masu zuwa don samar da maganin: • abu mai aiki a cikin insulin ɗan adam mai narkewa, • ƙarin abubuwa, gami da zinc chloride, glycerin giya na trihydric, metacresol, hydrochloric acid, sodium oxidanide, ruwa mai tsabta don allura. Addamar da miyagun ƙwayoyi yana cikin hanyar samar da mafita ga tsarin kulawa da cutarwa. Maganin shine abu mai kama da juna, wanda yawanci bashi da launi. Maganin babban kunshin shine gilashin gilashi. Ana sanya vials a cikin firiƙin taushi mai laushi a adadin adadin guda uku. An sanya fakiti mai laushi guda biyar, tare da umarnin don amfani, an sanya su cikin kwali na kwali na launin fari.
Side effects
Rashin halayen masu zuwa na iya faruwa yayin amfani da miyagun ƙwayoyi: • ƙaruwar ɗumi, • yanayin juyayi, • rawar jiki na yatsa, • yawan gajiya, • asara ƙarfi, rauni, • rage yawan jan hankali, • ciwon kai, tsananin farin ciki, • ,arin ci, jin tashin zuciya, • takewar tashewar zuciya, • cinyawar wata gabar jiki, • kumburin fuska, • Ragewar jini, • karancin numfashi, • huji, cuncushi.
Contraindications
Ba za a yi amfani da magani na Aktrapid Hm ba a gaban ɗayan waɗannan contraindications: • nuna rashin damuwa ga abubuwan haɗin jikin mutum, • sukari na jini, • halayen rashin lafiyan insulin, • tumbin β-sel daga cikin tsibirin na huɗa, wanda ke tasowa daga yanayin hormonal da jagoranci don rage yawan sukarin jini.
Haihuwa da lactation
Bayanan da ake samu yanzu yana nuna cewa cutar cututtukan cuta ko kuma wasu abubuwan da ba a ke so ba a gano tayi yayin amfani da Actrapid. A lokaci guda, ana ba da shawarar saka idanu sosai game da masu juna biyu masu ciwon sukari da kuma amfani da wannan magani. An tabbatar da cewa buƙatar sinadaran mai aiki na faruwa daga sati na sha huɗu na ciki da sannu-sannu yana ƙaruwa. Bayan haihuwa, buƙatar insulin ya ragu, amma bayan ɗan gajeren lokaci ya koma matakin da ya gabata. Yayin shayarwa, an yarda da amfani da maganin. Wani lokaci ana buƙatar canjin sashi don dogara da tasirin mai haƙuri.
Aikace-aikacen: hanya da fasali
Ana amfani da miyagun ƙwayoyi Actrapid Hm Penfill subcutaneously da cikin ciki. An tsara mafi kyawun sashi ne ta likitan halartar gwargwadon gwajin da aka yi. Saboda gaskiyar cewa aikin insulin mai narkewa gajere ne, ɗayan manyan shawarwari lokacin amfani da shi shine buƙatar haɗaka wannan magani tare da tsawan insulins ko matsakaiciyar matsakaiciyar matsakaici.Bukatar yau da kullun don insulin mai narkewa, a matsayin mai mulkin, ya bambanta daga ƙarni uku zuwa ɗayan raka'a ɗaya na kilogram na nauyin jiki. Wani lokacin buƙatar insulin ya wuce ƙimar dijital da aka nuna a marasa lafiya masu kiba ko a samartaka. Gabatar da magani ya kamata a aiwatar da rabin sa'a kafin abinci. Yakamata a yiwa allurar ciki sau biyu a cikin sassan jiki ta yadda za'a iya cire allurar da kullun a wuri guda. Hakanan ana bada shawarar yin hankali tare da gudanar da subcutaneous domin ware don haɓakar haɗari na mafita a cikin jini. Ana samun mafi saurin ɗaukar hankali lokacin da aka gabatar da shi zuwa yankin na ciki. Don gudanar da subcutaneous gwamnatin, haƙuri dole ne bi da yawa sauki dokoki. Waɗannan sun haɗa da masu zuwa: 1. Kafin amfani da Actrapid, ya kamata a bincika maganin a hankali. Ya kamata ya zama sutura, abu mara launi. Idan an sami girgije, lokacin farin ciki ko wata sabani, ba a haramta amfani da irin wannan magani ba. 2. Kafin gudanarwa, yana da kyau a wanke hannuwanku sosai, da kuma wurin jiko. 3. Buɗe ƙwanƙarar sirinji ka saka sabon allura, ya dunƙule ta har iyakar. Kowane allura na gaba na ɗan adam ya kamata a yi tare da sabon allura. 4. Bayan fitar da allura daga abin toshe kwalaba, tare da hannu guda shirya wurin allurar ta hanyar tattara fatar a wani karamin faifan, tare da dayan, duba sirinji don abinda ke ciki ya fita. Tabbatar cewa babu kwari a cikin murfin. 5. Saka allura cikin shafawa kuma sanya abinda ke ciki na vial a karkashin fata. 6. Bayan an saka, fitar da allura, rike wurin allura na dan kankanin lokaci. 7. Cire allurar daga hannun kuma ka watsar dashi. Gudun cikin jijiya na iya gudana ne ta kwararrun masana.
Yin hulɗa tare da wasu kwayoyi
Akwai kwayoyi da yawa waɗanda ke shafar matakan glucose a cikin jiki yayin amfani da haɗin gwiwa tare da Actrapid Hm. Don haka, kwayoyi waɗanda ke da tasiri mai yawa akan monoamine oxidase da angiotensin suna canza enzyme, har ma da kwayoyi kamar su tetracycline, ethyl- (para-chlorophenoxy) -isobutyrate, dexfenfluramine, cyclophosphamidum, masu haɓaka aikin anabolic a jiki, suna da ikon haɓaka aikin insulin mutum. Diuretics, roba androgens, heparin, maganin tricyclic antidepressants, glucocorticosteroids, psychotropic kwayoyi, abubuwan iodinated na tyrosine amino acid na iya haifar da kishiyar sakamako mai illa ga insulin mai narkewa. A karkashin aikin 3,4,5-trimethoxybenzoate methylreserpate da salicylic acid analgesics, canji a cikin matakin glucose a cikin jini mai yiwuwa ne, duka a cikin matakan raguwa da haɓaka.
Yawan abin sama da ya kamata
A halin yanzu, ba a gano kashi na magani na Actrapid ba, wanda zai iya haifar da yawan abin sama da ya kamata. A lokaci guda, lokacin da ya faru, raguwar sukari na jini a ƙasa da ƙayyadaddun tsari zai yiwu. A wannan yanayin, alamomin masu zuwa suna bayyana: • ciwon kai, • rarrabuwa a sararin samaniya, • asarar ƙarfi, rashin ƙarfi, • increasedara yawan zagi, • canji a cikin bugun zuciya, • rawar jiki na yatsunsu, • yawan tashin hankali, • raunin magana, • hangen nesa mai rauni, • yanayin baƙin ciki , • rushewar zuciya. Idan raguwar sukari baya haifar da rikitarwa mai wahala, to mai haƙuri zai iya cire kansa ta hanyar ɗaukar glucose a baki. Don waɗannan dalilai, ana ba da shawarar cewa mutane masu ciwon sukari koyaushe suna da abinci mai daɗi ko abin sha tare da su. A batun yayin da, sakamakon rage yawan sukari na jini, mai haƙuri ya yi hasarar hankali, ana buƙatar gudanar da maganin nan da nan game da maganin rage zafin cikin, wanda kwararren gwani ne kawai zai iya yin hakan.
Umarni na musamman
Canjawa zuwa wani magani na insulin ya kamata a aiwatar dashi a karkashin kulawar likita mai tsafta. Game da keta tsarin tsarin abinci, da haɓaka cikin aikin yau da kullun, ana buƙatar daidaita sashi. Ci gaban cututtuka na kodan da hanta na iya rage buƙatar insulin saboda raguwar hanyoyin aikin ta. A lokaci guda, abin da ya faru na cututtukan ƙwayar cuta na iya zama tushen ƙara yawan sashi na miyagun ƙwayoyi. Hakanan sashi na insulin na iya samun sauye sauye a cikin tabin hankali. Yin amfani da wasu magunguna yakamata a gudanar dashi tare da shawarwarin da suka dace na ƙwararrun masani. Tunda raguwa da haɓaka matakan sukari na jini suna yiwuwa yayin ɗaukar magani, wannan na iya yin tasiri ga taro. A irin waɗannan lokutan, ya kamata ku rabu da tuki da sauran ayyukan da ke buƙatar ƙara kulawa.
Magungunan Aktrapid Hm Penfill yana da samfuran samfurori masu zuwa tare da nau'ikan bakan aiki: Apidra Solostar, Gensulin R, Biosulin R, Gansulin R, Insulin R bio R, Insuran R, Rosinsulin R, Insuman Rapid GT, Rinsulin R, Vosulin-Rsp, Novorap , Insuvit N, Insugen-R, Insular kadari, Farmasulin N, Humodar R, Himulin Regular.
Nazarin Magunguna
Marasa lafiya da ke amfani da miyagun ƙwayoyi Actrapid Hm, har zuwa mafi girma, lura a cikin kyakkyawan shugabanci tasiri da saurinsa. Wasu marasa lafiya sun sami sakamako masu illa yayin gudanar da ƙananan ƙwayoyi na ƙananan ƙwayoyi, amma sau da yawa wannan shine sakamakon maganin da aka zaɓi da kyau.
Lasisin harhada magunguna LO-77-02-010329 wanda aka kwanan watan Yuni 18, 2019
Yadda ake amfani: sashi da hanya na jiyya
Matsayi da hanyar gudanar da maganin an ƙayyade su daban-daban a cikin kowane yanayi akan abubuwan glucose a cikin jini kafin abinci da 1-2 sa'o'i bayan abinci, kazalika ya dogara da matsayin glucosuria da halayen hanyar cutar.
Ana gudanar da maganin s / c, cikin / m, in / in, mintuna 15-30 kafin cin abinci. Hanyar gudanarwa mafi yawancin lokuta shine sc. Tare da ketoacidosis mai ciwon sukari, coma mai ciwon sukari, a lokacin aikin tiyata - in / in da / m.
Tare da monotherapy, yawan sarrafawa yawanci sau 3 a rana (idan ya cancanta, har zuwa 5-6 sau a rana), ana canza wurin allura kowane lokaci don guje wa ci gaban lipodystrophy (atrophy ko hauhawar mai mai subcutaneous).
Matsakaicin adadin yau da kullun shine 30-40 LATSA, a cikin yara - 8 IEaukaka, to, a cikin matsakaicin kashi na yau da kullun - 0.5-1 PIECES / kg ko 30-40 LIKE sau 1-3 a rana, idan ya cancanta - 5-6 sau a rana. A cikin adadin yau da kullun wanda ya wuce 0.6 U / kg, dole ne a gudanar da insulin a cikin nau'in 2 ko fiye da allura a cikin sassan daban-daban na jiki.
Yana yiwuwa a haɗu tare da insulins masu aiki na dogon lokaci.
Ana tattara maganin insulin daga murfin ta hanyar huɗa tare da allura mai kaɗa ta roba mai zartar da murhu bayan an cire maɓallin alumuran tare da ethanol.
Tambayoyi, amsoshi, sake dubawa game da miyagun ƙwayoyi Actrapid NM Penfill
Bayanin da aka bayar an yi shi ne don ƙwararrun likitoci da magunguna. Cikakken bayani game da magani yana kunshe ne a cikin umarnin da aka haɗe zuwa marufin da mai masana'anta. Babu wani bayani da aka sanya akan wannan ko wani shafin yanar gizon mu wanda zai iya canza matsayin roko na musamman ga kwararrun.Hulɗa da ƙwayoyi
Akwai kwayoyi da yawa waɗanda ke shafar buƙatar insulin. Hypoglycemic sakamako na insulin inganta baka hypoglycemic jamiái, monoamine oxidase hanawa, angiotensin tana mayar enzyme hanawa, carbonic anhydrase hanawa, zabe beta-blockers, bromocriptine, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, kwayoyi lithium salicylates .
Tasirin hypoglycemic na insulin yana raunana ta hanyar hana hana haihuwa, glucocorticosteroids, hormones thyroid, thiazide diuretics, heparin, maganin tricyclic antidepressants, sympathomimetics, hormone girma (somatropin), danazol, clonidine, jinkirin alli tashar blockers, diafenin, diafenin.
Beta-blockers na iya rufe alamun bayyanar cututtukan hypoglycemia kuma yana sa ya zama da wahala a murmure daga cutar rashin ƙarfi.
Octreotide / lanreotide na iya haɓaka da rage buƙatar jiki ga insulin.
Barasa na iya haɓaka ko rage tasirin insulin.
Actrapid ® NM za'a iya ƙara zuwa waɗancan mahaɗa waɗanda aka san cewa suna dacewa. Wasu kwayoyi (alal misali, kwayoyi waɗanda ke ɗauke da thiols ko sulfites) lokacin da aka kara su zuwa maganin insulin na iya haifar da lalata.
Yanayin ajiya na miyagun ƙwayoyi
Adana miyagun ƙwayoyi a zazzabi of 2 ° C zuwa 8 ° C (a firiji), amma ba kusa da injin daskarewa ba. Kar a daskare. Adana harsashi a cikin kwali don kare daga haske.
Don buɗe takaddun katako:
- Kada a ajiye a firiji. Adana a zazzabi da ba ya wuce 30 ° C na makonni 6.
Ya kamata a kiyaye Act NM Penfill ® daga abubuwa masu zafi da haske. Ayi nesa da isar yara.
Umarnin don amfani
Dangane da umarnin don amfani, ana amfani da sashi na Actrapid NM ta likita a cikin kowane yanayi daban-daban dangane da yanayin haƙuri. Lokacin amfani da Actrapid NM a cikin tsararren tsari, ana ba da shi sau da yawa sau 3 a rana (watakila har zuwa 5-6 sau). Za'a iya gudanar da maganin a cikin subcutaneously, intramuscularly ko intravenously.
A cikin minti 30 bayan aiwatar da maganin, dole ne ku ci abinci. Tare da zaɓi na mutum na maganin insulin, yana yiwuwa a yi amfani da Actrapid NM a hade tare da insulins masu aiki na dogon lokaci. Actrapid NM za a iya haɗu da shi a cikin sirinji guda tare da sauran insulins da aka tsarkake sosai. Lokacin da aka haɗu da shi tare da dakatar da zinc na insulin, dole ne a yi allura nan da nan. Lokacin da aka haɗe shi da insulins masu aiki da tsayi, HM actrapid dole ne a fara zana shi a cikin sirinji.
Amfani da haɗin gwiwa na corticosteroids, masu hana MAO, hana rigakafin hormonal, barasa, jiyya tare da hormones na thyroid na iya haifar da karuwa a cikin buƙatar insulin.
Samu wanda aka yi wa rantsuwa MUSUROOM na kusoshi! Za a tsaftace kusoshi a cikin kwanaki 3! .Auki.
Yadda za'a iya daidaita matsin lamba na hanzari bayan shekaru 40? Girke-girke mai sauki ne, a rubuce.
Gaji basur? Akwai hanyar fita! Ana iya warke shi a gida cikin fewan kwanaki, kuna buƙatar.
Game da kasancewar tsutsotsi yace ODOR daga bakin! Sau daya a rana, sha ruwa tare da digo ..
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Ice cream na Strawberry
Da fatan za a tabbatar cewa kai mutum ne. An hana damar amfani da wannan shafin saboda mun yi imani cewa kuna amfani da kayan aikin atomatik don duba gidan yanar gizon. ... -
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