Nau'in Mexico na farko da nau'in maganin cututtukan sukari na 2 a matsayin sabon rigakafi ga mutane

Syringes zai zama abu na ƙarshe - an gwada nasara cikin sabon maganin kwayar cutar ta DNA cikin mutane

07/03/2013 a 12:19, views: 16304

Godiya ga haɓaka sabuwar hanyar kulawa, mutanen da ke fama da ciwon sukari na 1 ba da daɗewa ba za su iya mantawa game da sirinji da injections na insulin. A halin yanzu, Dokta Lawrence Steinman daga Jami'ar Stanford ya ce an yi nasarar gwada sabuwar hanyar magance nau'in cutar ta 1 a cikin mutane kuma za a iya amfani da ita sosai wajen lura da wannan cuta a nan gaba.

Abin da ake kira “jigilar allurar rigakafi” yana aiki ta hanyar dakatar da tsarin rigakafi a matakin DNA, wanda hakan yana ƙarfafa samar da insulin. Haɓaka Jami'ar Stanford na iya zama farkon rigakafin DNA a duniya wanda za'a iya amfani dashi don kula da mutane.

“Wannan alurar rigakafin tana daukar wani tsarin daban daban. Lawrence Steinman ya ce takamaiman matakin na rigakafi ne, maimakon kirkirar da takamaiman maganin rigakafi kamar allurai na yau da kullun ko kuma cutar shan inna, ”in ji Lawrence Steinman.

An gwada maganin ne akan gungun masu aikin agaji 80. An gudanar da binciken a cikin shekaru biyu kuma ya nuna cewa marasa lafiya waɗanda suka sami magani bisa ga sabon hanyar sun nuna raguwa a cikin ayyukan sel wanda ke lalata insulin a cikin tsarin rigakafi. A lokaci guda, babu wasu sakamako masu illa bayan ɗaukar maganin.

Kamar yadda sunan ya nuna, allurar rigakafin ba a yi nufin hana wata cuta ba, amma don a yi maganin wata cuta da ta kasance.

Masana kimiyya, suna gano nau'ikan leukocytes, manyan "mayaƙa" na tsarin rigakafi, kai farmaki a kan jijiya, sun kirkiro wani magani wanda zai rage adadin waɗannan sel a cikin jini ba tare da ya shafi sauran bangarorin tsarin rigakafi ba.

Mahalarta gwaji sau ɗaya a mako don watanni 3 sun sami allurar rigakafin sabuwar allurar. A layi daya, sun ci gaba da gudanar da insulin.

A cikin rukuni na kulawa, marasa lafiya da suke karbar allurar insulin sun sami magani na placebo maimakon maganin alurar riga kafi.

Masu kirkirar maganin sun ba da rahoton cewa, a cikin ƙungiyar gwaji da ke karɓar sabon ƙwayar magani, an sami babban ci gaba a cikin aikin ƙwayoyin beta, waɗanda sannu a hankali sun dawo da ikon samar da insulin.

Lawrence Steinman, daya daga cikin marubutan wannan binciken ya ce: "Mun kusa isa don fahimtar mafarkin kowane mai ilimin rigakafi: mun koyi yadda za a kashe abubuwan da ke tattare da tsarin rigakafi ba tare da yin tasirin komai ba," in ji Lawrence Steinman, daya daga cikin marubutan wannan binciken.

Ana daukar nau'in 1 na cutar sankarar cuta mafi muni fiye da ciwon sukari na "fellowan'uwanka" 2.

Kalmar ciwon sukari da kanta wata kalma ce ta kalmar Helenanci “masu ciwon suga”, ma'anarta “Ina shiga wani abu, ta hanyar”, “Ina gudana”. Tsohon likitan Areteus na Cappadocia (30 ... 90 AD) ya lura a cikin marasa lafiya polyuria, wanda ke da alaƙa da gaskiyar cewa ruwayen da ke shiga jikinsu suna gudana ta ciki kuma an keɓance su ba su canzawa. A cikin 1600 AD e. an ƙara ciwon sukari a cikin kalmar mellitus (daga lat. mel - zuma) don nuna alamar ciwon sukari tare da dandano mai kyau na fitsari - ciwon sukari.

Cutar sankarau insipidus ce aka sani tun a zamanin da, amma har zuwa karni na 17 babu banbanci tsakanin ciwon sukari da insipidus na ciwon suga. A cikin XIX - farkon ƙarni na XX, babban aiki akan insipidus na ciwon sukari ya bayyana, haɗin haɗin ciwo tare da Pathology na tsarin juyayi na tsakiya kuma an kafa ƙwayar ƙwayar cuta ta baya. A cikin kwatancen asibiti, kalmar “ciwon sukari” galibi tana nufin ƙishirwa da ciwon sukari (ciwon sukari da insipidus na sukari), duk da haka, akwai “wucewa” - ciwon sukari na phosphate, ciwon sukari na koda (saboda ƙarancin ƙoshin glucose, baya haɗuwa da ciwon sukari), da sauransu.

Type 1 diabetes mellitus wata cuta ce wacce babbar alama ce ta kamuwa da cuta cuta ce mai saurin yaduwa - sukarin jini, polyuria, a sakamakon hakan ƙishirwa, asarar nauyi, yawan cin abinci, ko rashin sa, rashin ingantaccen lafiya. Ciwon sukari (mellitus) yana faruwa a cikin cututtuka daban-daban wanda ke haifar da raguwa a cikin kira da ɓoye insulin. Ana gudanar da bincike game da rawar da ya samo asali.

Nau'in na 1 na ciwon sukari na iya haɓaka kowane zamani, amma mutane na ƙuruciya (yara, matasa, manya waɗanda shekarunsu bai haura 30) galibi suna fama da cutar. Hanyar pathogenetic na haɓaka nau'in ciwon sukari na 1 an samo asali ne akan karancin samar da insulin ta hanyar ƙwayoyin endocrine (β-sel of the islets of Langerhans of the pancreas), lalacewarsu ta lalacewa a ƙarƙashin rinjayar wasu abubuwan pathogenic (kamuwa da cuta, damuwa, cututtukan autoimmune da sauransu).

Nau'in nau'in 1 na ciwon sukari na 15% na duk cututtukan cututtukan cututtukan sukari, sau da yawa yana tasowa a cikin ƙuruciya ko lokacin samartaka. Babban hanyar magani shine injections na insulin wanda ke daidaita metabolism na haƙuri. Idan ba a kula da shi ba, nau'in 1 na ciwon sukari na ci gaba cikin sauri kuma yana haifar da rikitarwa mai yawa, kamar ketoacidosis da ciwon sukari, wanda ke haifar da mutuwar mai haƙuri.

Siffofin ci gaban ciwon sukari

Kamar yadda kuka sani, ciwon sukari cuta ce mai ƙima wanda yake lalacewa cikin aiki. Tare da haɓaka nau'in cuta ta 1, tsarin garkuwar jiki yana cutar da ƙwayoyin beta na yanayin islet.

Sakamakon haka, sun daina samar da insulin na sukari da ke rage sukari wanda ya zama dole ga jikin mutum. Wannan cutar ta shafi mafi yawan matasa. A yayin lura da ciwon sukari na nau'in farko, marasa lafiya suna buƙatar ɗaukar alluran hormone a koyaushe, in ba haka ba sakamako mai kisa zai faru.

A cikin nau'in ciwon sukari na 2, samar da insulin ba ya tsayawa, amma ƙwayoyin da aka yi niyya basu daina amsawa ba. Irin wannan ilimin haɓaka shine haɓaka yayin jagorancin jagorancin rayuwa mara kyau a cikin mutanen da suka girmi shekaru 40-45. A lokaci guda, ga waɗansu, da yiwuwar samun rashin lafiya yana da girma sosai. Da farko dai, waɗannan mutane ne da ke ɗauke da kayan gado da kuma kiba. A yayin lura da nau'in ciwon sukari na 2, marasa lafiya suna buƙatar bin madaidaicin abinci mai gina jiki da hoto mai aiki. Bugu da ƙari, mutane da yawa dole ne su ɗauki magungunan hypoglycemic don sarrafa abun cikin sukari.

Ya kamata a lura cewa tsawon lokaci, nau'in ciwon sukari na farko da na biyu yana haifar da rikice-rikice iri-iri. Tare da ci gaba da cutar, ƙwaƙwalwar hanji yana faruwa, ƙafafun ciwon sukari, retinopathy, neuropathy da sauran sakamakon da ba a iya warwarewa ba.

Lokacin da kuke buƙatar yin kararrawa kuma ku nemi likitanka don taimako? Cutar sankarau cuta ce mai rashin hankali kuma tana iya kusan asymptomatic. Amma har yanzu, ya kamata ka kula da irin waɗannan alamun:

1. M ƙishirwa, bushe baki.
2. Urination akai-akai.
3. Yunwar mara hankali.
4. Dizziness da ciwon kai.
5. Wanƙwasa cuta da ƙwanƙwalwa.
6. Doduwa da kayan aiki na gani.
7. Rage nauyi mai nauyi.
8. Barci mara kyau da gajiya.
9. Rashin sake zagayowar lokacin haila a cikin mata.
10. Abubuwan jima'i.

Nan gaba kadan zai iya yiwuwa a nisantar da ci gaban "cutar rashin lafiya." Alurar rigakafin nau'in 1 na iya zama madadin magani mai ra'ayin mazan jiya tare da maganin insulin da wakilai na hypoglycemic.

Kashe rigakafi

"Babu wanda ya taɓa gaya mani cewa yin rigakafin rigakafin na iya haifar da mummunan cututtuka irin su ciwon sukari, cututtukan ƙwayar cuta, cutar Alzheimer ... Kodayake wannan duka a cikin umarnin likita," Sergei Shlyonsky ya fara labarinsa da farin ciki. - Kuma babu inda aka ba iyaye ainihin dalilin. Kodayake, bisa ga dokar Federationungiyar Tarayyar Rasha, likitoci sun wajabta yin wannan (dokar Lamari mai lamba 157-FZ na 1998 "A kan immunoprophylaxis"). "

Gosha mai shekaru 6 yana da mura na dogon lokaci. Duk wannan lokacin, iyaye sun rubuta rashin yarda game da alurar riga kafi. Bayan 'yan kwanaki kafin a yi wa allurar rigakafin, malamin makarantar yara ya ba mahaifiyar wata takarda cewa ya kamata a yi wa ɗanta rigakafin. Gaucher ya gabatar da allurar rigakafi sau uku da aka shirya don kare yaron daga kamuwa da cutar kumburin kumburi da kumburi.

Kusan nan da nan bayan allurar, jaririn ya sami rauni, rauni, rasa ci, ya fara shan ruwa da yawa.

"Bayan mako guda bayan haka, ya juya yaron," in ji Sergey cikin takaici. - Kusan cikin rashin lafiyar da suka kawo asibiti. Duk alamun cutar sankarau sun bayyana. Ni da matata kawai ban sani ba a lokacin - ba mu da wani abu makamancin wannan a cikin kowace kabila. Ina jagorantar rayuwa mai kyau: Gudun, babu barasa, taba, daga bazara zuwa kaka, muna tare da yara a cikin ƙasar a cikin gandun daji na Pine. Wannan shine, Na fahimci abin da ake buƙatar aikata don yara su sami rigakafi mai ƙarfi. Me zai kashe wannan rigakafin? Tunanina, bayan na yi nazarin tsaunin wallafe-wallafe, rigakafi ne. ”

Yanzu Gosh an tilasta shi ya zauna a kan insulin. Hoto: Daga cikin ma'ajiyar bayanan sirri / Daga adana kayan tarihin S. Shlyonsky

Tabbatar da komai

Sergey ya ci gaba da cewa "Yayana yana asibiti, na ga cewa sabbin yara masu dauke da cutar sankarau suna zuwa a kowace rana," in ji Sergey. - M kusanta da kowa: akwai akwai alurar riga kafi? Akwai - ɗaya na mako guda, ɗaya don biyu, ɗaya don wata ɗaya. Na juya ga masu bincike, masu gabatar da kara, amma nan da nan suka ce: sashen kiwon lafiya ba zai sami hanyar alaƙa tsakanin rigakafin cutar ba. Koyaya, masana ilimin kimiya na endocrinologists a Asibitin Yara Na 3 sun fahimci gaskiyar cewa alurar riga kafi na iya zama sanadiyar ci gaban ciwon sukari. ”

Mahaifin mara mahaifin ya je likitocin da ya sani: a cikin tattaunawar sirri da Sergey, amma ba su voye cewa yana da gaskiya ba. Amma sun ƙi tallafawa a bayyane - kowa yana jin tsoron martabarsu da matsayin su, wanda za'a iya ɓace saboda irin wannan “magana mai faɗi”.

A ina jarirai ke samun kansa?

Sergei, malamin tarihi ta hanyar horo, ya fara nazarin matsalar da kanshi, ya goge adadi da yawa na adabi da ayyukan kimiyya na shahararrun likitocin. A cikin ofishin edita, ya nakalto mana wata wasika daga masanin kanikancin dabbobi, Farfesa Gorodilova ga Kwamitin Kasa game da ilimin halittu: Duk yadda yanayin wucin gadi yake samu, dukkansu suna zuwa rashin daidaituwa na tsarin T-cell, yana haifar da aiki da kuma tsari ga rikice-rikice da yawa a lafiyar yarinyar. Har ila yau, allurar tana hanzarta, ta hanzarta aiwatar da hanyoyin '' kashe kudade ', ta hanyar inganta jikin mutum zuwa tsufa, daga nan cututtukan tsufa na matasa. A cikin ilimin cutar kanjamau, rashin daidaituwa tsakanin saurin amsar ƙwayar cuta da haɓakar tumo shine ainihin asali. Haɓakar ciwon kansa yana gaba da adadin ƙwayoyin ƙwayoyin lymphoid waɗanda suke amsawa game da shi, wanda, ƙari da hakan, yana da niyyar magance magungunan rigakafi na rigakafi masu zuwa - rigakafin. "

Kuɗi maimakon rantsuwa. Likita Yuri Arutsev - game da maganin zamani

"Ga martanin immunologist din," in ji Sergey. - Amma har yanzu ban iya fahimtar inda yara ƙanana suka sami cutar kansa daga?! Yanzu ina da amsoshi. Kuma ina buƙatar yin wani abu tare da waɗannan amsoshin ... "

Diarin masu ciwon sukari

Statisticsididdiga masu ciwon sukari gaba ɗaya suna da ban tsoro, in ji Sergey Shlyonsky. Kuma ya nakalto "littafin Jagora na masu ciwon sukari" wanda Astamirova da Akhmanov, wanda likitan ilimin yara ya basu a asibitin: “Ina tunatar daku cewa har yanzu muna dogaro da wadatar magunguna daga kasashen waje, cewa ba duk likitocinmu suna shirye don bi da koyarwa tare da bude zuciyar cewa Babban abu a cikin magungunan mu shine jami'ai, ba likitoci ba, cewa har yanzu muna da isassun scammers kuma wasu daga cikinsu suna haskakawa ta talabijin sama da shekara guda. Koyaya, gaskiyar yanayin al'amura yana ƙara zama mai faɗi a cikin kafofin watsa labaru, kuma manyan shahararrun masanan kimiyyar ba su da tsoron faɗi gaskiya. Kuma ita ce: a cikin Rasha, ba masu ciwon sukari miliyan biyu ko uku ba, amma sau biyu, sau uku ko sau hudu. "

Me yasa yasa aka sami karuwa mai yawa a yawan lokuta an yi rikodin kwanan nan?

"Gwargwadon yadda na gano, allurar tana dauke da sinadarin mercury, gubar da sauran munanan abubuwa," Sergei ya ci gaba da binciken nasa. - Kuma da umarnin na Ma'aikatar Lafiya na Rasha Federation of Maris 23, 1998 Ba. 82 "A goge na Mercury shirye-shirye da mahadi daga jihar rajista na magunguna" ya haramta yin amfani da Mercury a shirye-shiryen likita. Amma har yanzu tana cikin allurar rigakafi, kuma ba wanda ke bin wannan umarni! ”

Ofaya daga cikin rigakafin rashin hankali, Sergei, tare da abokan sa likitocin sunyi la'akari da rigakafin mura. Kwayar cutar mura sau da kullun tana canzawa, kuma ba lallai ba ne cewa cutar ta gaba za ta haifar da lahani cikin alurar. Don haka maganin ba zai yi aiki ba! Bugu da kari, likitoci sun ce kuna buƙatar yin la'akari da sigogin jikin mutum, farawa da halaye na rigakafi da ƙare tare da halayen ƙwayar cuta. Ba tare da waɗannan dalilai ba, yin alurar riga kafi na iya ƙarewa cikin bala'i.

Ba a tambayar iyaye ba

"Me yasa wannan wasan?" Dr. Gennady Markov akan biyan sabis na likita da karuwar yawan marasa lafiya

Abokin Sergei Shlyonsky shi ma ya kawo aikace-aikace a Roszdravnadzor da ofishin mai gabatar da kara: 'yarsa mai shekaru 14 ta sha wahala daga alurar riga kafi. An yi mata allurar tare da DTP a ƙarƙashin kafada kuma an sami raguwar cutar Polio. Wata ma’aikaciyar jinya ce ta shigo cikin aji ta ce wani allurar rigakafi ya isa kuma kowa ya tafi neman maganin, kuma yarda daga iyaye za a iya zuwa gobe. Kafin yin rigakafin, babu wanda ya tambaya game da lafiyar lafiyar yara, yarinyar ta sami mura a wannan lokacin.

Wurin allurar ya kasance mai raɗaɗi na makonni biyu, an rufe yarinyar da amai. Yaron yana tsunduma cikin wasannin ƙwararru - masu motsa jiki, sannan duk sakamakon wasanni nan da nan ya lalace. Mako guda baya, ta rasa ci, ƙishirwa, yawan urination, rauni ya bayyana. Bari mu je asibiti. Bayan da aka juya cewa yarinyar ta tsalle sukari, an dauke ta zuwa asibiti a asibiti. Maganin cutar sankarau ce. Af, babu wani daga cikin dangi da ya wahala kafin. Yanzu yarinyar tana kan nakasa.

An kirkiro maganin cutar sankara

Sako Greyman » 11.02.2015, 21:56

Gwaje-gwajen da suka yi nasara a cikin bera suna ba da bege ga ƙirƙirar ingantaccen rigakafin kamuwa da cuta mai nau'in 1, wanda ke shafar miliyoyin matasa a duniya. Sabuwar ƙwayar magani ta dakatar da lalata ƙwayoyin beta waɗanda ke samar da insulin.

Masana kimiyya a Jami'ar St. Louis sun sami wata hanya ta hana nau'in cutar sankarau ta cikin mice ta toshe hanyoyin sarrafa kansa na alhakin kashe ƙwayoyin cututtukan beta. Wataƙila, a madadin wannan fasaha, zai yuwu a ƙirƙiri hanyoyi masu inganci don yin rigakafi da magani na ɗayan cututtukan da suka fi haɗari da haɗari.

Cutar sankara (mellitus) cuta ce mai ƙwanƙwasa rai wanda tsarin rigakafin jiki yake "kuskure" yana lalata sel da ke samar da insulin. Sakamakon haka, ciwon sukari yana haifar da rashi na hormones da hyperglycemia - haɓaka abun ciki na glucose a cikin jini. Ba kamar nau'in ciwon sukari na II ba, nau'in ciwon sukari na I ba ya inganta ta tsufa, amma yana faruwa ne da farko a cikin matasa har ma da yara. Abin takaici, babu wani magani ga wannan cuta, kuma dole ne marassa lafiya su lura da sukarin jininsu su dauki insulin duk rayuwarsu. Amma duk da haka, ciwon sukari yana da alaƙa da rikice-rikicen rayuwa masu yawa, alal misali, haɗarin mutuwa daga cututtukan zuciya a cikin marasa lafiya da ke fama da ciwon sukari sau da yawa sama da mutane masu lafiya. A cikin duka, akwai kimanin mutane miliyan 250 masu ciwon sukari a cikin duniya, sama da miliyan 2.5 a Rasha.Masana sun lura da karuwa a duniya a yawan lokuta, kuma yawan mutanen da ke dauke da cutar hawan jini wanda ba su nemi taimako ba na iya zama sau da yawa.

Wani sabon binciken, wanda Dr. Thomas Burris ya jagoranta kuma aka buga a Endocrinology, yana ba da sabuwar hanya don hana ciwon sukari, ba kawai bi da alamun ta ba. A cewar Thomas Barris, sabon magani na iya rage jinkirin ci gaban nau'in I ciwon sukari ko ma cire buƙatar allurar insulin.

Har izuwa yanzu, masana kimiyya sun san cewa akalla nau'ikan sel biyu na rigakafin kwayoyin halitta suna da alhakin ci gaban nau'in ciwon sukari irin na I. Haka kuma, aikin nau'in sel uku (TH17) ba a sani ba. Thomas Barris da abokan aiki sun gano cewa wasu masu karɓa na nukiliya suna taka muhimmiyar rawa wajen haɓaka ƙwayoyin Th17. Haka kuma, sun kasance iya dakatar da autoimmune cuta a cikin da dama gwaji mice, ajiye su beta Kwayoyin daga hallaka.

Masana kimiyya sun haɓaka wani abu na musamman wanda ke toshe ROR alpha da gamma t receptors antagonist wanda ake kira SR1001. Wannan abu yana rage bayyanar cututtukan sukari a cikin mice kuma ana iya amfani dashi don hana halakar ƙwayoyin beta na samar da insulin.

Bayanan da aka samo sun nuna cewa sel Th17 suna taka muhimmiyar rawa a cikin ci gaban nau'in ciwon sukari na nau'in. Masu binciken sunyi la'akari da magungunan da ke aiki akan waɗannan ƙwayoyin suna da matukar cika alkawari. Irin waɗannan kwayoyi zasu taimaka wajen kawar da ciwon sukari a farkon matakan ci gaba da hana duk matsalolin kiwon lafiya da haɗari ga rayuwa. A duk duniya, sabon magani na iya ceton miliyoyin rayuka da adana biliyoyin daloli waɗanda yanzu aka kashe akan maganin rashin insulin magani da kuma alamomin bayyanar cututtuka.

'Dauke shi ba zan iya ba'

Little Gaucher ya gurbata. Yayinda aka ba shi izinin shiga cikin makarantar kindergarten na tsawon awanni 2-3 kawai, saboda yaron yana buƙatar sadarwa tare da takwarorinsa.

"Lokacin da aka ba shi kyauta mai lemo ga Sabuwar Shekara, dansa da hawaye ya ba ni:" Takeauke shi, Papa, amma ba zan iya ba. " Ni kaina na shirya tsinke kaina, ”Sergey tana ajiyar zuciya.

Me yasa ba'a yin nazarin sakamakon tasirin alurar riga kafi?

"Muna rayuwa ne a cikin duniyar duniya da ke cike da talauci," in ji Sergey. "Ana yin kuɗi akan komai, gami da kwayoyi da kuma alluran rigakafi."

Kuma yaranmu suna biyan sa.

Ana buƙatar allurar rigakafi

Likita mafi tsada. Albashin mai maganin cututtukan zuciya a Yaroslavl - 6,000 rubles

Tatyana Zamiralova, shugaban yankin Roszdravnadzor a yankin Yaroslavl: "Bai dace a ƙi iyaye su yiwa 'ya'yansu alurar riga kafi ba, kodayake hukuncin ya kasance tare da su. Bayan rigakafi, an inganta rigakafi, kuma wannan zai kara kare jariri daga kamuwa da cuta. Idan an yiwa yaro allurar, ba zai kamu da cutar ta hanyar saduwa da masu cutar ba. Amma kana buƙatar samun rigakafin in babu likita contraindications, wanda likitan halartar ke ƙaddara, alal misali, wasu cututtukan ƙwayar cuta, kasancewar cututtukan m masu saurin kamuwa. Ko shirya shiri na yara don alurar riga kafi wajibi ne kuma likitan halartar ya yanke shawarar. Ranar alurar riga kafi, likitan yara na duba shi. Kafin yin rigakafin, dole ne a ba wa iyaye izinin sanar da yarda ko su ki yin rigakafin. ”

Iyaye suna da hakki na farko

Alexander Kostlivtsev, chiropractor: “Shekaru 40-50 da suka wuce, mutane sun ci abinci daban, suna shakar iska, da wuya a yi amfani da maganin rigakafi. Tare da taimakon alurar rigakafin a wannan lokacin, yana yiwuwa a iya magance cututtukan da yawa masu saurin kamuwa.

Amma duniya ta canza: kwayoyi, gubobi, allergens sun keta matsayin rigakafin ɗan adam. Amsawa ga rigakafin ya zama mafi m, rikitarwa mai rikitarwa ya bayyana.

Jiharmu tana ba da zaɓi - don yi wa yaro allurar ko a'a. Muna da kamfen na rigakafi na son rai, kuma ya kamata iyaye su fahimci yadda alhakin wannan matakin yake. Alurar riga kafi ba ƙaramin harbi ba ne ko kuma saɓo, haɗari ne na humanan adam, sakamakon abin da ke da wahalar faɗi. Bayan sun bar shawarar zuwa likitan yara, iyayen su ne ke da alhakin makomar yaransu. ”

Shin maganin tarin fuka zai warkar da ciwon sukari?

A yau akwai hanyoyi masu yuwuwar hanyoyin magance wannan nau'in ciwon suga, wanda yawancinsu ana yinsu ne ko dai kan ka'idodin ɓoye tsarin garkuwar jiki wanda ke lalata ƙwayoyin insulin, ko kan sake fasalin aikinsa ta yadda tsarin “kewaya” kwayar beta.

Abin takaici, waɗannan hanyoyin suna ɗaukar nauyin sakamako masu illa da yawa na saka jari. Don haka, masana kimiyya da masana ilmin halitta daga ko'ina cikin duniya ba su daina neman ingantacciyar hanya don magance wannan cutar ba, wanda zai sami sakamako mai kyau tare da ƙarancin mummunan sakamako ga jikin ɗan adam.

Don haka masana kimiyya daga Diungiyar ciwon sukari na Amurka suka gudanar da wani bincike tare da burin kafa yadda maganin da aka yi amfani da shi wajen maganin cutar tarin fuka ya shafi ciwon sukari na 1.

Gwajin bincike, wanda ya samu halartar mutane 150 masu fama da cutar sankara daga shekaru 18 zuwa 60, sun nuna cewa maganin tarin fuka yana da tasirin magani.

Masanin ilimin ƙwayar cuta daga Amurka Denise Faustman ya yi imanin cewa allurar rigakafin cutar tarin fuka da aka bai wa mutanen da ke fama da kamuwa da ciwon sukari na 1 na iya dakatar da lalata ƙwayoyin T, waɗanda ke lalata ƙwayoyin da ke ɗaukar magungunan ƙwayoyin cuta na ƙasashen waje. Bincike ya nuna cewa allurar rigakafin tarin fuka, ana gudanar da shi a duk sati biyu, ya daina mutuwar muhimman sel.

Nan gaba kadan, ana shirin ci gaba da binciken tare da allurar rigakafin tarin fuka ga adadi mafi yawa na marasa lafiya.

Sha'ir groats don ciwon sukari: kaddarorin masu amfani, girke-girke, contraindications

Irin ƙwaro warkarwa da magani Properties. Ta yaya kwaro zai taimaka wa masu ciwon sukari?

Mene ne matsayin yawan sukarin jini a cikin mata? Kara karantawa a wannan labarin.

Daga cutar mura

Don ciwon sukari, ana ba da shawarar ku sami ƙwayar cutar mura a kowane lokaci. Sakamako na mutuwa a cikin wannan rukuni na marasa lafiya daga kamuwa da cuta suna da yawa. An kuma nuna wannan rigakafin ga mata masu juna biyu. Alurar riga kafi mafi kyau an yi a tsakiyar kaka: Oktoba - Nuwamba. Bai kamata masu haƙuri su daina shan magungunan da endocrinologist ya umarta ba.

Nau'in Mexico na farko da nau'in maganin cututtukan sukari na 2 a matsayin sabon rigakafi ga mutane

Kowa ya ji labarin: rigakafin cutar sankara ya riga ya bayyana, kuma ba da daɗewa ba za a yi amfani da shi don hana ciwo mai tsanani. Salvador Chacon Ramirez, shugaban Gidauniyar Nasara kan Cutar Cutar Raya, da Lucia Zárate Ortega, Shugaban Mexungiyar Mexico na Cutar Cutar Kanjamau da Kula da cututtukan Autoimmune Pathologies.

A wannan taron, an gabatar da maganin alurar riga kafi a hukumance, wanda ba zai iya hana cutar ba kawai, har ma da rikice-rikice na masu ciwon sukari.

Yaya maganin yake aiki kuma yana da ikon shawo kan cutar? Ko kuma wani yaudarar kasuwanci ne? Waɗannan tambayoyin zasu taimaka fahimtar wannan labarin.

Sabon Saukewar Ciwon Cutar

Autohemotherapy sabuwar hanya ce ta lura da ciwon sukari irin na 1 a cikin yara da manya. Nazarin irin wannan magungunan sun tabbatar da cewa bashi da illa. Masana kimiyya sun lura cewa marasa lafiyar da aka yi musu allurar ta lokaci sun ji wani ci gaba na kiwon lafiya.

Wanda ya kirkiri wannan hanyar shine Mexico. Jorge González Ramirez, MD ya yi bayanin jigon wannan hanyar. Marasa lafiya suna karbar samfurin jini na 5 cubic mita. cm kuma aka gauraye da ruwan gishiri (55 ml). Hakanan, irin wannan cakuda yana sanyaya zuwa +5 digiri Celsius.

Sannan ana yin maganin cutar sankarar hanta na sukari ga mutane, kuma a kan lokaci, ana daidaita metabolism. Sakamakon alurar riga kafi yana da alaƙa da ayyukan da ke gaba a jikin mai haƙuri. Kamar yadda kuka sani, zafin jikin mutum mai lafiya shine digiri 36.6-36.7. Lokacin da aka gudanar da rigakafi tare da zazzabi na digiri 5, rawar jiki yana faruwa a jikin mutum. Amma wannan yanayin damuwa yana da amfani mai amfani ga metabolism da kurakurai na kwayoyin.

Ainihin alurar riga kafi tsawon kwanaki 60. Haka kuma, dole ne a maimaita kowace shekara. A cewar mai kirkirar, maganin zai iya hana ci gaban mummunan sakamako: bugun jini, gazawar koda, makanta da sauran abubuwa.

Koyaya, gudanar da allurar rigakafi ba zai iya ba da garantin magani 100% ba. Wannan magani ne, amma ba mu'ujiza bane. Rai da lafiyar mai haƙuri ya kasance a hannunsa. Dole ne ya bi shawarar kwararrun sosai kuma a yi masa allurar a duk shekara. Da kyau, ba shakka, motsa jiki don maganin ciwon sukari da abinci na musamman, ma, ba a soke su ba.

Sakamakon Nazarin Kiwon Lafiya

Kowane sakan 5 na duniya, mutum ɗaya ya kamu da ciwon sukari, kuma kowane sakan 7 - wani ya mutu. A cikin Amurka kadai, kusan mutane miliyan 1.25 suna fama da ciwon sukari na 1. Theididdiga, kamar yadda muke gani, suna cike da takaici.

Yawancin masu bincike na zamani suna da'awar cewa maganin guda ɗaya wanda ya saba mana zai taimaka wajen shawo kan cutar. Anyi amfani dashi sama da shekaru 100, shine BCG - maganin rigakafin cutar tarin fuka (BCG, Bacillus Calmette). Zuwa shekarar 2017, an kuma yi amfani da ita wajen maganin cutar kansa.

Lokacin da tsarin rigakafi yana da sakamako mai lahani ga farji, ƙwayoyin cuta na pathogenic T sun fara haɓakawa a ciki. Suna mummunan cutar da ƙwayoyin beta na tsibirin na Langerhans, suna hana samar da hormone.

Sakamakon binciken ya kasance mai ban mamaki. Mahalarta wannan gwajin an allurar dasu da allurar rigakafin cutar tarin fuka sau biyu a duk kwanaki 30. Ta tattara sakamakon, masu binciken ba su sami kwayoyin T a cikin marasa lafiya ba, kuma a wasu masu ciwon sukari da ke kama da nau'in cuta ta 1, cutar ta sake fara haifar da hormone.

Dokta Faustman, wanda ya shirya waɗannan karatun, yana son yin gwaji tare da marasa lafiya waɗanda ke da dogon tarihin ciwon sukari. Mai binciken yana son cimma sakamako na warkewa mai ɗorewa da inganta maganin ta yadda zai zama ainihin magani ga masu ciwon sukari.

Za'a gudanar da sabon binciken a cikin mutane masu shekaru 18 zuwa 60. Zasu karɓi rigakafin sau biyu a wata, sannan su rage tsarin zuwa sau ɗaya a shekara na shekaru 4.

Bugu da kari, an yi amfani da wannan maganin a lokacin kuruciya daga shekaru 5 zuwa 18. Binciken ya tabbatar da cewa ana iya amfani dashi a cikin wannan nau'in tsufa. Ba a gano halayen da ba su dace ba ba, kuma yawan adadin gafara bai karu ba.

Yin rigakafin ciwon sukari

Duk da yake rigakafin ba a yadu ba, ƙari, ana cigaba da bincike.

Yawancin masu ciwon sukari da mutanen da ke cikin haɗari dole ne su bi matakan kariya na ra'ayin mazan jiya.

Koyaya, irin waɗannan matakan zasu taimaka ma rage yiwuwar haifar da rashin lafiya da kuma matsalolinta. Babban ƙa'idar ita ce: jagorantar rayuwa mai kyau tare da ciwon sukari na 2 kuma ku bi abinci.

• Bi abinci na musamman wanda ya ƙunshi hadaddun carbohydrates da abinci mai fiber,
• Yi motsa jiki aƙalla sau uku a mako
• kawar da karin fam,
• a kai a kai saka idanu matakin glycemia,
• a sami isasshen bacci, a daidaita ma'auni tsakanin hutawa da aiki,
• Guji matsananciyar damuwa
• guji bacin rai.

Ko da an gano mai haƙuri da cutar sankarar bargo, mutum bai kamata ya fusata ba. Zai fi kyau a raba wannan matsalar ga ƙaunatattun waɗanda za su goyi bayan hakan a cikin wannan mawuyacin lokaci. Dole ne a tuna cewa wannan ba magana ce ba, kuma suna zaune tare da shi na dogon lokaci, yana ƙarƙashin duk shawarar likita.

Kamar yadda kake gani, maganin zamani yana neman sababbin hanyoyin magance cutar. Wataƙila ba da daɗewa ba, masu bincike za su ba da sanarwar ƙirƙirar sabuwar allurar rigakafi ga masu ciwon sukari. A halin yanzu, dole ne ka gamsu da hanyoyin magani na ra'ayin mazan jiya.

Bidiyo a cikin wannan labarin yayi magana game da sabon rigakafin cutar sankara.

M jiyya - nau'ikan rigakafin cutar sankara

Prevaarfafawa da kuma yawan mace-mace daga nau'in 1 da nau'in ciwon sukari na 2 wanda ke tilasta masu ilimin kimiyya a duk duniya don haɓaka sababbin hanyoyin da dabaru game da magance cutar.

Zai zama abin ban sha'awa ga mutane da yawa don koyo game da sababbin hanyoyin magani, kirkirar maganin alurar rigakafin cutar sankara, sakamakon binciken duniya a wannan yankin.

Ciwon sukari

Hanyoyin da za a bi don kamuwa da ciwon sukari na 2 suna da ɗan bambanci da waɗanda ake amfani da su wurin lura da ciwon sukari na 1.

Sakamakon magani ya sami amfani da hanyoyin gargajiya yana bayyana bayan dogon lokaci. Tooƙarin rage nasarar tasirin haɓaka mai kyau a cikin jiyya, likitancin zamani yana haɓaka ƙarin magunguna, da amfani da sababbin hanyoyin, da samun kyakkyawan sakamako mafi kyau.

A cikin lura da ciwon sukari na 2, ana amfani da rukuni na 3 na kwayoyi:

Ayyukan waɗannan magungunan an yi nufin su ne:

• rage yawan glucose,
• hana ƙwayar glucose ta ƙwayoyin hanta,
• motsawar insulin insulin ta hanyar aiki a jikin sel,
• katange insulin juriya daga sel da tsokoki na jikin mutum,
• ƙarancin insulin hankalin mai da ƙwayoyin tsoka.

Yawancin kwayoyi suna da raunin sakamako a jikin su:

• nauyi riba, hypoglycemia,
• fitsari, itching a kan fata,
• narkewar tsarin cuta.

Mafi inganci, abin dogara ne Metformin. Yana da sassauci a aikace-aikace. Kuna iya ƙara yawan kashi, hada tare da wasu. Lokacin haɗin gwiwa tare da insulin, yana halatta don bambanta sashi, rage rage insulin.

Mafi tabbacin magani ga nau'in 1 da nau'in ciwon sukari na 2 shine kuma shine insulin far.

Bincike anan bai tsaya cik ba. Ta amfani da nasarorin da aka samu a aikin injiniyan tsirrai, an sami daidaitattun abubuwa na gajarta da na nesa.

Wadanda suka fi fice sune Apidra - insulin gajere kuma Lantus - mai dadewa.

Amfani da su gabaɗaya kamar yadda zai yuwu ya zama keɓaɓɓen ɗarin kwayar halitta ta insulin da ƙwaƙwalwar ƙwayar ƙwayar cuta ta hanji, kuma yana hana yiwuwar rikitarwa.

Tsarin lura da jini na kwamfuta wanda aka kirkira ta S. Leviticus tana kulawa da cututtukan fata. Ana tattara takarda alƙawarin bayan yanke bayanan komputa na lantarki, wanda mai haƙuri ya ɗauka na kwanaki 5.

Don ci gaba da kwanciyar hankali a cikin lura da marasa lafiya da ke da nau'in ciwon sukari na 1, ya kuma haɓaka kayan aiki da ke haɗe da bel.

Kullum yakan yanke shawarar sukari na jini kuma, ta amfani da famfo na musamman, yana saka adadin insulin ta atomatik.

Sabbin hanyoyin kwantar da hankali

Mafi kyawun hanyoyin maganin cutar sankara sun haɗa da:

• amfani da kara sel,
• alurar riga kafi
• cascading jini,
• dasawa da amare ko sassan jikinta.

Amfani da ƙwayoyin tsutsa hanya ce ta ƙarshe. Ana aiwatar da shi a cikin asibitocin musamman, alal misali, a cikin Jamus.

A cikin yanayin dakin gwaje-gwaje, ƙwayoyin kara suna girma waɗanda aka dasa a cikin haƙuri. Sabbin tasoshin, ana kafa kyallen takarda a cikin sa, ana dawo da ayyuka, matakan glucose an daidaita shi.

Alurar riga kafi ta kasance mai karfafa gwiwa. Kusan rabin ƙarni, masana kimiyya a Turai da Amurka suna ta aiki a kan rigakafin cutar sankara.

Hanyar sarrafa kansa na tafiyar matakai na autoimmune a cikin ciwon sukari mellitus an rage shi zuwa lalata sel Kwayoyin ta T-lymphocytes.

Maganin, wanda aka kirkira ta amfani da nanotechnology, yakamata ya kiyaye sel betacin, sake mayar da wuraren da suka lalace kuma ya karfafa mahimmancin T-lymphocytes, tunda ba tare da su jikin zai kasance mai saurin kamuwa da cututtukan fata ba.

Ana amfani da jujjuyawar jini ko kuma zubar da jini mai zurfi don cututtukan ƙwayar cuta mai wahala.

An dasa jini ta hanyar matatun musamman, ana wadatar da shi tare da magunguna masu mahimmanci, bitamin. An daidaita shi, an sami 'yanci daga abubuwan guba waɗanda ke lalata tasoshin daga ciki.

A cikin manyan ɗakunan shan magani na duniya, a cikin mafi yawan lokuta marasa bege tare da rikitarwa mai rikitarwa, ana amfani da juyar da sashin ƙwayar jikin mutum ko ɓangarorinsa. Sakamakon ya dogara da ingantaccen wakili mai kin amincewa.

Bidiyo game da cutar sankara daga Dr. Komarovsky:

Sakamakon Nazarin Kiwon Lafiya

Dangane da bayanai daga 2013, masana kimiyya na Dutch da Amurka sun kirkiro maganin BHT-3021 game da ciwon sukari na 1.

Ayyukan maganin shine maye gurbin ƙwayoyin beta na pancreas, suna maye gurbin kanta a maimakon su don lalata ƙwayoyin T-lymphocytes.

Kwayoyin beta da aka adana na iya sake fara samar da insulin.

Masana kimiyya sun kira wannan maganin a matsayin "allurar-baya-mataki" ko kuma juyawa. Shi, yana hana tsarin rigakafi (T-lymphocytes), yana mayar da rufin insulin (sel beta). Yawancin lokaci allurar rigakafi suna ƙarfafa tsarin na rigakafi - aiki kai tsaye.

Dr. Lawrence Steiman na Jami'ar Stanford ya kira allurar "rigakafin farko na DNA a duniya," saboda ba kamar, rigakafin cutar mura ce ta yau da kullun, ba ta samar da takamaiman matakin kariya. Yana rage ayyukan ƙwayoyin rigakafi waɗanda ke lalata insulin ba tare da cutar da sauran sassan jikinta ba.

An gwada kayan rigakafin akan mahalarta 80 da suka ba da kansu.

Nazarin ya nuna kyakkyawan sakamako. Ba a gano sakamako masu illa ba. Matsayi na C-peptides ya karu a duk fannoni, wanda ke nuna maidowar cututtukan fata.

Samuwar insulin da C-peptide

Don ci gaba da gwaji, an canza lasisin magani ga Tolerion, kamfanin ƙirar ƙwayoyin cuta a California.

A cikin 2016, duniya ta sami labarin sabon abin mamaki. A wurin taron, Shugaban kungiyar Mekziko na Cutar Cutar Kankara da Kula da Cututtukan Autoimmune, Lucia Zarate Ortega, da Shugaban Gidauniyar Nasara kan Cutar ciwon sukari, Salvador Chacon Ramirez, sun gabatar da sabon nau'in na 1 da nau'in allurar rigakafin cutar ta 2.

Algorithm na maganin alurar riga kafi shine kamar haka:

1. Mai haƙuri yana karɓar ƙwayoyin jini 5 daga jijiya.
2. Ana saka 55 ml na ruwa na musamman wanda aka haɗe da ruwan gishiri a cikin bututu na gwaji tare da jini.
3. Ana aika ruwan cakuda da ke cikin firiji kuma a ajiye shi har sai cakuda ta yi sanyi zuwa digiri 5 Celsius.
4. Sannan ya mai da zafin jiki zuwa yanayin jikin mutum na digiri 37.

Tare da canji a zazzabi, abubuwan da ke haɗuwa suna canzawa da sauri. Sakamakon sabon abun da ke ciki zai zama madaidaicin maganin Mexico. Kuna iya adana irin wannan maganin har tsawon watanni 2. Jiyyarta, tare da abinci na musamman da kuma motsa jiki suna ɗaukar shekara guda.

Kafin magani, ana gayyatar marasa lafiya nan da nan, a Mexico, don yin cikakken bincike.

Abubuwan da aka samu na nazarin Mexico an tabbatar da su a cikin ƙasashen duniya. Wannan yana nufin cewa maganin Mexico ya karbi "tikiti zuwa rayuwa."

Mahimmancin rigakafin

Tunda sababbin hanyoyin magani ba su da kowa ga masu fama da ciwon sukari, rigakafin cutar ya kasance batun gaggawa, saboda nau'in ciwon sukari na 2 shine kawai cutar, ikon rashin rashin lafiya wanda galibi ya dogara da mutumin da kansa.

Shawarwarin hanawa sune ka'idodi na ingantacciyar salon rayuwa:

1. Abincin da ya dace da al'adun abinci.
2. Tsarin shan ruwa.
3. Rayuwa, salon rayuwa.
4. Kamawar kayan maye.
5. Karyata munanan halaye.
6. Ikon cututtukan cututtukan da ke gudana.
7. Waraka har zuwa karshen cututtukan, cututtukan da suke ci gaba.
8. Bincika don kasancewar helminths, ƙwayoyin cuta, parasites.
9. Tare da tsawaita amfani da magunguna, ba da gudummawar jini lokaci-lokaci don bincike.

Ingantaccen abinci mai mahimmanci shine mahimmanci a cikin rigakafin.

Wajibi ne a iyakance abinci mai daɗi, gari, abinci mai ƙima sosai. Ka ware barasa, soda, abinci mai sauri, abinci mai sauri da tsawa, wanda ya hada da cutarwa, abubuwan kiyayewa.

Foodsara abincin shuka mai wadatar fiber:

Sha ruwa tsarkakakke har zuwa lita 2 a lokacin.

An buƙata don shigar da kanka da la'akari da yiwuwar motsa jiki a matsayin al'ada ta al'ada: doguwar tafiya mai tafiya, wasanni na waje, hutu, azuzuwan gwaji.

Daga kamuwa da cutar huhu

Tare da ciwon sukari, an shawarci likitoci da kyau don yin rigakafin kamuwa da cututtukan cututtukan cututtukan fata. Ya kamata a kula musamman da abin da ya faru bayan alurar riga kafi ga masu ciwon sukari wanda shekarunsu suka wuce 65. Sinusitis, ciwon huhu da kuma meningitis sune wasu daga cikin cututtukan gefe a cikin wannan rukuni na marasa lafiya wanda zai iya faruwa sakamakon kamuwa da cuta tare da pneumococci.

A kan hepatitis b

Mutanen da ke da alamun nau'in 1 da nau'in ciwon sukari na 2 ana nuna su da alurar rigakafin cutar hepatitis B. An yi rikodin rubutun wannan allurar a cikin lokuta 2: a cikin mutane sama da shekaru 60. Ana iya yin irin wannan alurar rigakafin a cikin shawarar mai halartar mahaɗa da mai haƙuri da kansa. Wannan ya faru ne sakamakon karancin fitsarin alurar rigakafin a waccan shekarar. Akwai matsaloli a cikin yawan kiba.

Fiye da 50% na marasa lafiya da wannan cutar suna da matsalolin nauyi. Yankin mai mai yawa yana hana allurar rigakafin yin aiki daidai akan tsoka.

Allurar pertussis

Ciwon sukari na yiwuwa ne sakamakon rigakafin pertussis a cikin yara.

Amsar jikin mutum ga alurar riga kafi shine karuwa a samar da insulin tare da raguwar cututtukan fata, watau tsibirin Langrens, wanda yake hade da wannan sinadarin. Sakamakon na iya zama cututtuka 2: cututtukan jini da gudawa. Matsaloli bayan wannan alurar riga kafi na iya haifar da karancin glucose na jini. Wannan allurar ta ƙunshi ƙwayar pertussis. Ya kasance mai guba. Zai iya shafar jikin mutum ta hanyar da ba a iya faɗi ba. Sabili da haka, likitoci sun yanke shawarar gwada haɗin maganin rigakafin pertussis da ciwon sukari.

Rubella, Cutar mama da Cutar Kyanda

MMR yana ɗaya daga cikin sunayen likita. Abun da ya ƙunshi, watau rubella, yana shafar jikin yaron kamar cutar gaske. Madps da rubella an san su suna haifar da nau'in 1 na ciwon sukari. Idan yaro ya kamu da mahaifar, wanda ba shi da lafiya tare da rubella a lokacin haihuwa, daga baya bayan an ba da allurar rigakafin cutar rubella, masu ciwon sukari na iya haɓaka sakamakon hulɗa da ƙwayar cuta mai rauni tare da abin da ya riga ya kasance a jikin yarinyar. Tunda farji shine kashin bayan ƙwayar carnus, da yiwuwar haɓaka cutar sukari yana da yawa.

Abubuwan ƙuraje na ƙwayar kumbura (mumps), kamar ƙwayar cuta ta gaskiya, na iya shafar ƙwayar hanji da tsokani ƙwayar cuta. Tare da yanayin rauni na sashin ƙwayar cuta, haɗarin kamuwa da cututtukan ƙwayar cuta ya ragu har zuwa babban matakin. A lokaci guda, ƙwayoyin-alade kamar ƙwayoyin cuta marasa kyau suna shafar ƙwayoyin beta na pancreatic, suna kai hare-hare.

Hemophilus mura da maganin hepatitis B

Da yake amsawa ga interferon kyauta, jikin yaron ya fara lalata ƙwayoyin ƙwayoyin ƙwayoyin cuta.

Maganin rigakafin Hib zai iya haifar da cutar sukari. Akwai tabbataccen shaidar da ke nuna cewa yara waɗanda suka sami allurai 4 maimakon ɗayan guda sun kamu da cutar guda 1. Allurar hepatitis B kuma tana iya haifar da ciwon sukari na 1. Wannan na faruwa ne sabili da interferons na kyauta. Tsarin rigakafi yana mayar da martani ga waɗannan interferons a matsayin kwaro kuma yana kai hari da ƙwayoyin kansa.