Mai ciwon sukari mv 30 MG: farashin da umarni ga masu ciwon sukari

Ofayan mafi mahimmancin yanayi don nasarar cutar cututtukan ƙwayar cuta shine daidaitawar matakan glucose. Sabili da haka, lokacin siyan wakili na hypoglycemic Diabeton MV 30 MG, umarnin don amfani ya kamata a yi nazari a hankali don magance cutar sosai.

Kasancewar rukunin sulfonylurea na ƙarni na biyu, ƙwayar ta rage glucose jini kuma tana kawar da alamun cututtukan da ba su da insulin-da ke fama da cutar sankara.

Statisticsididdigar rashin jin daɗi sun nuna cewa kasancewar wannan cuta tana ƙaruwa kowace shekara. Abubuwa da yawa suna yin tasiri akan wannan, amma daga cikinsu, tsararraki da salon rayuwa mai santsi ya cancanci kulawa ta musamman.

Magungunan Diabeton MV 30 MG ba kawai yana daidaita matakin glycemia ba, amma yana hana ci gaban yawancin rikice-rikice na ciwon sukari, alal misali, retinopathy, nephropathy, neuropathy da sauransu. Babban abu shine sanin yadda ake shan magani daidai, wanda za'a tattauna a wannan labarin.

Babban bayanin magunguna

Diabeton MV 30 sanannen shahararren magani ne na kwaskwarimar sakin magunguna a duk duniya. Kamfanin Faransa na kera magunguna Les Laboratoires Servier Іndustrie ne ya samar da shi.

Ana amfani da wakili na hypoglycemic don cututtukan da ba na insulin-insulin ba, lokacin da motsa jiki na motsa jiki da kuma daidaitaccen abinci ba zai iya rage glucose jini ba. Bugu da kari, daya daga cikin alamun amfani da miyagun ƙwayoyi shine rigakafin rikice-rikice kamar microvascular (retinopathy da / ko nephropathy) da cutar macrovascular (bugun jini ko infarction na myocardial).

Babban sinadaran da ke amfani da maganin shine gliclazide - wani sinadarin sulfonylurea. Bayan gudanar da baki, wannan bangaren yana cikin komai na hanji. Abun da ke ciki yana haɓaka a hankali, kuma an kai matsakaicin matakin cikin awa 6-12. Yana da mahimmanci a lura cewa cin abinci ba ya shafar maganin.

Sakamakon gliclazide yana nufin haɓaka samar da insulin ta ƙwayoyin beta na pancreas. Bugu da kari, sinadarin yana da tasirin hawan jini, wato, yana rage yuwuwar fitar jini a cikin kananan tasoshin. Gliclazide kusan kusan metabolized ne a cikin hanta.

Cire kayan yana faruwa ne tare da taimakon kodan.

Umarnin don amfani da miyagun ƙwayoyi

Mai sana'antawa ya samar da maganin a cikin nau'ikan allunan kwayoyi daban-daban (30 da 60 mg), ban da haka, kawai marasa lafiyar manya ne zasu iya shan ta.

Za a iya siyan Diabeton MV 30 MG a kantin magani kawai tare da takardar sayen magani na likita. Saboda haka, likita ya ƙayyade yiwuwar yin amfani da waɗannan magungunan, an ba da matakin glycemia da kuma yanayin lafiyar mai haƙuri.

An bada shawara don shan maganin sau ɗaya a rana yayin abincin safe. Don yin wannan, dole ne a hadiye kwamfutar hannu kuma a wanke shi da ruwa ba tare da taunawa ba. Idan mara lafiya ya manta shan maganin kwayar a kan lokaci, yin shakku da yawan maganin ba haramun bane.

Sigar farko na maganin haihuwar jini shine 30 MG kowace rana (1 kwamfutar hannu). A cikin nau'in ciwon sukari da ba a kula da shi ba, wannan dabarar zata iya ba da isasshen iko na matakan sukari. In ba haka ba, likita da kaina yana ƙaruwa da yawan ƙwayoyi ga mai haƙuri, amma ba a baya ba bayan kwanaki 30 na shan kashi na farko. An yarda da datti ya cinye gwargwadon iko a kowace rana na ciwon sukari MV 30 zuwa 120 MG.

Akwai wasu gargadin game da amfani da miyagun ƙwayoyi a cikin mutane fiye da 60 shekara, kazalika da marasa lafiya da ke fama da barasa, koda ko gajiya hanta, glucose-6-phosphate dehydrogenase rashi, pituitary ko adrenal kasawa, cututtukan zuciya da jijiyoyin jini. A irin waɗannan yanayi, ƙwararren likita ya zaɓi sashi na maganin.

Umarnin da aka haɗe ya ce yakamata a adana maganin a 30 ° C daga ƙananan yara. Ya kamata a nuna rayuwar shelf akan marufi.

Bayan wannan lokacin, an haramta yin magani.

Contraindications da yiwuwar cutar

Murar kwayar cutar sankara (MV 30 MG) tana cikin contraindicated a cikin marassa lafiya 'yan shekaru 18 da haihuwa. Wannan iyakance ya faru ne sakamakon karancin bayanai game da lafiyar kudaden yara da matasa.

Hakanan babu wani gogewa ta amfani da wakilin hypoglycemic a lokacin daukar ciki da lactation. A lokacin haila, mafi kyawun zaɓi don sarrafa glycemia shine ilimin insulin. Game da batun shirin daukar ciki, zaku daina amfani da magunguna masu rage sukari da canzawa zuwa alluran hormone.

Baya ga contraindications na sama, ƙaramin wasiƙar tana da jerin ƙwayoyin cuta da halaye masu yawa waɗanda aka hana Diabeton MV 30 amfani da su. Wadannan sun hada da:

ciwon sukari wanda yake dogaro da kansa
amfani da miconazole,
mai ciwon sukari ketoacidosis,
hypersensitivity ga babban ko karin aka gyara,
coma mai cutar kansa
hepatic da / ko kasawa na kasa (a cikin mummunan tsari).

Sakamakon amfani da shi ta hanyar da ba ta dace ko yawan shan ruwa ba, halayen da ba a so. Idan sun faru, dole ne a dakatar da shan miyagun ƙwayoyi kuma a hanzarta neman taimako daga likita. Kuna iya buƙatar dakatar da amfani da shi idan gunaguni na mai haƙuri yana da alaƙa da:

Tare da saurin raguwa a cikin matakan sukari.
Tare da jin dindindin na yunwar da karuwar gajiya.
Tare da rikicewa da gajiya.
Tare da damuwa, tashin zuciya da amai.
Tare da ciwon kai da dizziness.
Tare da raunana maida hankali.
Tare da m numfashi.
Tare da wahayi hangen nesa da magana.
Tare da tashin hankali, rashin damuwa da bacin rai.
Tare da cirewar tsoka mara lafiyan.
Tare da hawan jini.
Tare da bradycardia, tachycardia, angina pectoris.
Tare da amsawar fata (itching, fitsari, erythema, urticaria, Quincke edema).
Tare da tsoratarwa halayen.
Tare da kara yin gumi.

Babban alamar yawan yawan abin sama da ya wuce shine hypoglycemia, wanda za'a iya kawar dashi tare da abinci mai wadataccen cikin carbohydrates mai narkewa mai sauƙi (sukari, cakulan, 'ya'yan itãcen marmari). A cikin wani mummunan yanayin, lokacin da mara lafiya na iya rasa hankalinsa ko kuma ya fada cikin rashin lafiya, dole ne a kai shi asibiti cikin gaggawa. Hanya guda don daidaita sukari na jini shine ta hanyar gudanar da glucose. Idan ya cancanta, ana aiwatar da maganin tiyata.

Haɗuwa da wasu hanyoyin

A gaban cututtukan concomitant, yana da matukar muhimmanci ga mai haƙuri ya ba da rahoton wannan ga kwararrun likitansa. Rage irin wannan mahimmancin bayanan na iya haifar da mummunar cutar tasirin ƙwayar cutar sankara MV 30 da kanta.

Kamar yadda kuka sani, akwai magunguna da yawa waɗanda zasu iya haɓaka ko, a taƙaice, raunana tasiri na wakili na hypoglycemic. Wasu daga cikinsu na iya haifar da wasu sakamakon da ba a so.

Magunguna da abubuwan da ke haɓaka da yiwuwar yawan ƙwaƙwalwar ƙwayar cuta:

Miconazole
Fankamara
Ethanol
Sulfonamides.
Thiazolidinidones.
Acarbose.
Ultrashort insulin.
Magungunan rigakafin ƙwayar cuta marasa lalacewa.
Clarithromycin
Metformin.
Agonists na GPP-1.
MAO masu hanawa.
Dipeptidyl peptidase-4 masu hanawa.
Masu tallata Beta.
ACE masu hanawa.
Fluconazole
H2-histamine mai hana masu tallatawa.

Magunguna da abubuwanda ke haɓaka yiwuwar kamuwa da cuta:

Danazole
Chlorpromazine
Glucocorticosteroids,
Aikin,
Salbutamol,
Ritodrin
Terbutaline.

Ya kamata a lura cewa tsarin kulawa na lokaci-lokaci na abubuwan da suka dace na sulfonylurea da anticoagulants na iya haɓaka tasirin ƙarshen. Sabili da haka, a wasu yanayi, ya zama dole don daidaita sashi.

Don guje wa duk wani mummunan halayen, mai haƙuri yana buƙatar zuwa wurin ƙwararren likita wanda zai iya tantance ma'amala tsakanin kwayoyi.

Abubuwanda ke tasiri tasirin maganin

Ba wai kawai magani ko abin sama da ya kamata ba zai iya tasiri da tasiri na wakili mai narkewa a cikin Diabeton MV 30. Akwai wasu dalilai da dama waɗanda ke cutar da lafiyar lafiyar masu ciwon sukari.

Dalili na farko kuma mafi yawan dalilin rashin daidaituwa shine rashin yarda ko kuma rashin iyawar marasa lafiya (musamman tsofaffi) don sarrafa matsayin lafiyar su kuma bi duk shawarwarin likita na halartar.

Abu na biyu, daidai gwargwado shine daidaitaccen tsarin abinci ko abinci mara daidaituwa. Hakanan, tasiri na miyagun ƙwayoyi yana haifar da matsananciyar yunwa, gibba a shigar da canje-canje a cikin abincin da aka saba.

Bugu da ƙari, don cin nasara cikin nasara, mai haƙuri dole ne ya iya sarrafa adadin carbohydrates da ake amfani da shi da aikin jiki. Duk wani bata gari yana cutar sugar da lafiya.

Tabbas, cututtukan haɗin gwiwa suna taka muhimmiyar rawa. Da farko dai, waɗannan sune cututtukan endocrine da ke da alaƙa da glandar thyroid da glandon gland, da kuma na koda mai rauni da gazawar hepatic.

Sabili da haka, don cimma daidaituwa game da darajar glucose da kuma kawar da alamun cututtukan sukari, mai haƙuri da ƙwararrun likitansa suna buƙatar shawo kan ko aƙalla tasirin abubuwan da ke sama.

Kudin, sake dubawa da kuma analogues

Ana iya siyar da miyagun ƙwayoyi Diabeton MV 30 MG a kowane kantin magani ko kuma an umurce ta akan layi akan gidan yanar gizon official na mai siyarwa. Kudin maganin yana dogara da yawan allunan a cikin kunshin. Don haka, farashin kunshin wanda ya ƙunshi allunan 30 na MG 30 na kowane jeri daga 255 zuwa 288 rubles, kuma farashin kunshin wanda ya ƙunshi allunan 60 na 30 MG kowane jeri daga 300 zuwa 340 rubles.

Kamar yadda kake gani, maganin yana samuwa ga mai haƙuri tare da kowane matakin samun kudin shiga, wanda, ba shakka, babban ƙari ne. Bayan nazarin ingantattun sake duba lafiyar masu ciwon sukari, zamu iya samun wasu karshe game da wannan maganin:

Sauƙi mai amfani tare da allurar insulin.
Riskarancin haɗarin halayen masu illa.
Tushewar cutar glycemia.

Koyaya, a wasu yanayi, an sami raguwar saurin matakan sukari, wanda aka cire ta hanyar shan carbohydrates. Gabaɗaya, ra'ayin likitoci da marasa lafiya game da maganin yana da inganci. Ta hanyar yin amfani da allunan daidai kuma bi duk shawarar likita, zaku iya cimma matakan sukari na al'ada kuma ku guji sakamako masu illa. Dole ne a tunatar da cewa kawai waɗancan marasa lafiya waɗanda:

bi don dacewa da abinci mai kyau,
wasa wasanni
A daidaita tsakanin hutawa da aiki,
sarrafa glucose
yi kokarin kauce wa tashin hankali da baqin ciki.

Wasu suna amfani da miyagun ƙwayoyi a cikin gina jikin mutum don haɓaka ƙwayar tsoka. Koyaya, likitoci sunyi gargaɗin yin amfani da miyagun ƙwayoyi don wasu dalilai.

Tare da haɓakar halayen da ba su da kyau ko kuma dangane da contraindications, likita yana da matsala game da zaɓi na wani magani wanda zai iya samun sakamako irin wannan. Diabeton MV yana da yawa analogues. Misali, tsakanin kwayoyi masu dauke da gliclazide bangaren masu aiki, wadanda suka shahara sune:

Glidiab MV (140 rubles),
Glyclazide MV (130 rubles),
Diabetalong (105 rubles),
Diabefarm MV (125 rubles).

Daga cikin shirye-shiryen da ke kunshe da wasu abubuwa, amma samun tasirin hypoglycemic guda, mutum na iya rarrabe Glemaz, Amaril, Gliclada, Glimepirid, Glyurenorm, Diamerid da sauransu.

Yana da mahimmanci a lura cewa lokacin zabar magani, mai haƙuri yana ba da kulawa ba kawai don tasirinsa ba, har ma da farashinsa. Babban adadin analogues ya sa ya yiwu a zaɓi mafi kyawun zaɓi don rabo na farashin da inganci.

Ciwon sukari MV 30 MG - ingantaccen kayan aiki a lura da ciwon sukari na 2. Lokacin da aka yi amfani da shi daidai, maganin zai taimaka wajen rage abun cikin sukari da manta game da alamun "cuta mai daɗi" na dogon lokaci. Babban abu shine kada ku manta game da umarnin likita kuma ku jagoranci rayuwa mai lafiya.

Expertwararren masani daga bidiyon wannan labarin zaiyi magana game da sifofin likitancin Diabeton.

Tsari sashi:

Abun ciki:
Tabletaya daga cikin kwamfutar hannu ya ƙunshi:
Aiki mai aiki: gliclazide - 30.0 MG.
Fitowa: alli hydrogen phosphate dihydrate 83.64 mg, hypromellose 100 cP 18.0 mg, hypromellose 4000 cP 16.0 mg, magnesium stearate 0.8 mg, maltodextrin 11.24 mg, anhydrous colloidal silicon dioxide 0.32 mg.

Bayanin
Allunan fari, biconvex allunan hoto da aka zana da "DIA 30" a gefe guda kuma tambarin kamfanin a daya bangaren.

Rukunin Magunguna:

MAGANAR PHARMACOLOGICAL
Pharmacodynamics
Glyclazide shine mai samo asali na sulfonylurea, magani ne na hypoglycemic don gudanarwa na baka, wanda ya bambanta da magunguna masu kama da wannan ta hanyar kasancewar N - dauke da zobe heterocyclic tare da haɗin endocyclic.
Glyclazide yana rage haɗuwa da glucose na jini, yana ƙarfafa ɓoye insulin ta hanyar ƙwayoyin sel-tsibirin na Langerhans. Increaseara yawan ƙwaƙwalwar insprandial insulin da C-peptide sun ci gaba bayan shekaru 2 na maganin.
Baya ga tasirin metabolism na metabolism, gliclazide yana da tasirin jijiyoyin jini.
Tasiri kan rufin insulin
A cikin nau'in 2 na ciwon sukari na mellitus, ƙwayar ta sake farawa farkon farkon ƙwayar insulin a cikin martani ga ciwan glucose kuma yana haɓaka kashi na biyu na ɓoye insulin. An lura da haɓakar ƙwayar insulin a cikin martani ga tashin hankali saboda ci abinci ko gudanarwar glucose.
Tasirin cutar sankarar jiki
Glyclazide yana rage haɗarin ƙananan ƙwayoyin jini na jini, yana haifar da hanyoyin da zasu iya haifar da ci gaba da rikice-rikice a cikin ciwon sukari mellitus: hanawa cikin tarawar platelet da adhesion da raguwa a cikin abubuwanda ke haifar da abubuwa na faranti (beta-thromboglobulin, thromboxane B2), kazalika da sake dawo da aikin fibrinoly increasedara yawan aikin ƙwayar plasminogen mai aiki.
Lyarfin glycemic mai ƙarfi dangane da yin amfani da Diabeton® MV (HbA1c dabarun sarrafa glycemic mai ƙarfi ya haɗa da alƙawarin magani na Diabeton® MV da haɓaka ƙaddararsa a kan asalin cutar (ko kuma a maimakon) ingantacciyar ƙwaƙwalwar ƙwaƙwalwa kafin ƙara zuwa wani magani na hypoglycemic (alal misali, metformin, alpha-glucosidase inhibitor , wani asali na thiazolidinedione ko insulin.) Matsakaicin yawan yau da kullum na miyagun ƙwayoyi Diabeton patients MV a cikin marasa lafiya a cikin ƙungiyar kulawa mai ƙarfi shine 103 mg, matsakaicin kullun kashi ya 120 MG.
A kan tushen amfani da miyagun ƙwayoyi Diabeton ® MV a cikin ƙungiyar kulawa mai ƙarfi na glycemic (matsakaicin biyewa shekaru 4.8, matsakaici matakin HbA1c 6.5%) idan aka kwatanta da ƙungiyar kulawa mai kyau (matsakaici matakin HbA1c 7.3%), an nuna raguwa mai yawa na 10% haɗarin haɗari na haɗarin mitar macro- da rikitarwa na microvascular
An sami fa'idar ta hanyar rage girman haɗarin: manyan rikicewar ƙananan ƙwayoyin cuta ta hanyar 14%, farawa da ci gaban nephropathy da kashi 21%, abin da ya faru na microalbuminuria da 9%, macroalbuminuria da 30% da haɓakar rikicewar koda na 11%.
Fa'idodi na iko mai ƙarfi a cikin ƙwayar cuta yayin shan Diabeton® MV bai dogara da fa'idodin da aka samu tare da maganin rashin lafiyar ƙwayar cuta ba.

Pharmacokinetics
Bayan gudanar da baki, gliclazide yana cikin komai. Cigaba da gliclazide a cikin plasma yana ƙaruwa a hankali, yana isa ga tudun bayan awa 6-12. Musamman daidaiku sun yi karanci.
Cin abinci baya shafar matakin ɗaukar ƙwayar. Dangantaka tsakanin kashi da aka ɗauka (har zuwa 120 MG) da kuma yankin a ƙarƙashin murhun likitancin "lokacin taro" shine layi. Kimanin kashi 95% na magungunan suna ɗaure zuwa garkuwar plasma. Glyclazide yana cikin metabolized a cikin hanta kuma akasarin koda shine kodan: an fitar da hutun ne a cikin hanyar metabolites, kasa da kashi 1 cikin dari da kodan baya canzawa. Babu ƙwayoyin metabolites mai aiki a cikin jini.
Rabin rayuwar gliclazide shine matsakaita na awanni 12 zuwa 20. Ofimar rarraba shine kusan lita 30.
A cikin tsofaffi, babu canje-canje masu mahimmanci a cikin sigogi na pharmacokinetic.
Shan magungunan masu ciwon sukari ® MV a cikin kashi 30 MG sau ɗaya a rana yana tabbatar da kiyaye ingantaccen taro na glycazide a cikin jini na sama da 24 sa'o'i.

HANKALI GA YANZU
Nau'in nau'in ciwon sukari na 2 da ƙarancin ingantaccen aikin maganin abinci, aikin jiki da asarar nauyi.
Yin rigakafin rikice-rikice na ciwon sukari mellitus: rage haɗarin microvascular (nephropathy, retinopathy) da rikice-rikice na macrovascular (infarction na myocardial, rauni) a cikin marasa lafiya da nau'in ciwon sukari na 2 na mellitus ta hanyar sarrafa glycemic mai ƙarfi.

hypersensitivity to gliclazide, sauran abubuwan da ake amfani da su na sulfonylurea, sulfonamides ko kuma ga wadanda suka sha daga cikin magungunan,
nau'in ciwon sukari guda 1
fida mai fama da ciwon sukari,
mai tsanani game da koda ko gazawar hanta (a cikin waɗannan halayen, ana bada shawara don amfani da insulin)
concomitant far tare da miconazole (duba sashe "Haɗa tare da wasu kwayoyi"),
ciki da lactation (duba sashin "Cutar ciki da lokacin lactation"),
shekaru zuwa shekaru 18.

Ba'a ba da shawarar a yi amfani dashi a hade tare da phenylbutazone da danazole (duba sashin "hulɗa tare da wasu kwayoyi").
Tare da kulawa:
Tsofaffi, rashin daidaituwa da / ko abinci mara daidaituwa, raunin glucose-6-phosphate dehydrogenase, cututtukan cuta mai mahimmanci na tsarin zuciya, cututtukan zuciya, rashin daidaituwa ko ƙarancin ƙwayar cuta, rashin koda da / ko hanta, rashin lafiya na dogon lokaci tare da glucocorticosteroids (GCS), shan giya.

CIGABA DA CIKIN CIKIN SAUKI KYAUTA
Ciki
Babu gwaninta tare da gliclazide yayin daukar ciki. Bayanai game da amfani da wasu abubuwan da ake amfani da su na sulfonylurea yayin daukar ciki suna iyakatacce.
A cikin bincike a kan dabbobi na dakin gwaje-gwaje, ba a gano tasirin teratogenic na gliclazide ba.
Don rage haɗarin rikice-rikice na haihuwar haihuwa, ingantaccen iko (magani mai dacewa) na ciwon sukari mellitus ya zama dole.
Ba'a amfani da magungunan maganin ƙwayar cuta na baka a lokacin daukar ciki.
Insulin shine magani na zabi don maganin cututtukan siga a cikin mata masu juna biyu.
An bada shawara don maye gurbin ci na maganin ƙwayoyin cuta hypoglycemic na baki tare da maganin insulin duka a cikin yanayin da aka shirya yin ciki, kuma idan ciki ya faru yayin shan maganin.
Lactation
Yin la'akari da rashin bayanai akan cinikin gliclazide a cikin madarar nono da kuma haɗarin haɓakar ƙwararraki a cikin yaran da ke shayar da nono, ciyar da jarirai nono lokacin maganin tare da wannan magani.

KYAUTA DA ADDU'A
DARASI NA YI AMFANI DA KAWAI DON SAURAN ADDU'A.
Ya kamata a sha maganin da aka ba da shawarar (allunan 1-4, 30-120 mg) a baki, a lokaci 1 a rana, zai fi dacewa yayin karin kumallo.
An ba da shawarar a ƙwace kwamfutar hannu gaba ɗaya ba tare da tauna ko murƙushewa ba.
Idan ka rasa magunguna ɗaya ko sama ɗaya, baza ku iya ɗaukar babbar magani a kashi na gaba ba, yakamata ku ɗauki kashi da kuka ɓace gobe.
Kamar yadda yake tare da sauran magungunan hypoglycemic, ana buƙatar zaɓi kashi na miyagun ƙwayoyi a kowane yanayi daban-daban, gwargwadon taro na jini da glycosylated haemoglobin (HbA1c).
Farkon kashi
Yankin da aka ba da shawarar farko (gami da ga tsofaffi marasa lafiya, years 65 shekara) shine 30 MG kowace rana.
Game da isasshen iko, ana iya amfani da magani a cikin wannan adadin don maganin kulawa. Tare da rashin isasshen iko na glycemic, ana iya ƙara adadin kwayoyi na yau da kullun zuwa 60, 90 ko 120 MG.
Increaseara yawan kashi yana yiwuwa ba da farko ba bayan watan 1 na maganin ƙwaƙwalwar ƙwayar cuta a ƙayyadadden maganin da aka tsara a baya. Banda shi ne marasa lafiya waɗanda ba su raguwa da glucose din jini ba bayan makonni 2 na maganin. A irin waɗannan halayen, ana iya ƙara kashi 2 makonni biyu bayan farawar gudanarwa.
Matsakaicin shawarar da aka bayar na yau da kullun na miyagun ƙwayoyi shine 120 MG.

Sauyawa daga Diabeton ® Allunan kwayoyi 80 a cikin kwayoyi masu ciwon sukari ® 30 MG allunan kwaskwarimar da aka gyara
1 kwamfutar hannu 1 na miyagun ƙwayoyi Diabeton ® 80 MG za a iya maye gurbinsu da kwamfutar hannu 1 tare da ingantaccen saki Diabeton ® MV 30 MG. Lokacin canja wurin marasa lafiya daga Diabeton ® 80 MG zuwa Diabeton ® MV, ana bada shawarar kulawa da hankali glycemic.
Sauyawa daga wani maganin cututtukan jini zuwa Diabeton ® 30 MG allunan kwaskwarimar da aka gyara
Magungunan Diabeton ® MV Allunan tare da ingantaccen saki na 30 MG za'a iya amfani dashi maimakon wani magani na hypoglycemic don maganin baka. Lokacin canja wurin marasa lafiya da ke karɓar wasu magunguna na hypoglycemic don sarrafawa na baka zuwa Diabeton ® MV, yakamata a yi la'akari da kashi da rabin rayuwa. A matsayinka na mai mulkin, ba a bukatar lokacin juyawa.
A kashi na farko yakamata ya zama mil 30 sannan sannan akasashi ya danganta da maida hankali kan glucose na jini.
Lokacin da aka maye gurbin Diabeton ® MV tare da abubuwanda suka samo asali na sulfonylurea tare da dogon kawar rabin rayuwa don guje wa hauhawar jini wanda ya haifar da tasirin mahaɗin jini biyu, zaku iya dakatar da shan su na kwanaki da yawa. Maganin farko na miyagun ƙwayoyi Diabeton ® MV a lokaci guda shine 30 MG kuma, idan ya cancanta, ana iya ƙaruwa nan gaba, kamar yadda aka bayyana a sama.
Hada kai tare da wani magani na hypoglycemic
Za a iya amfani da ciwon sukari ® MB a hade tare da biguanides, alpha-glucosidase inhibitors ko insulin.
Tare da rashin isasshen iko na glycemic, ƙarin insulin far ya kamata a wajabta shi tare da saka idanu na likita.

Tsofaffi marasa lafiya
Ba a buƙatar gyaran fuska don marasa lafiya waɗanda suka girmi shekaru 65 ba.

Marasa lafiya tare da gazawar koda Sakamakon binciken asibiti ya nuna cewa ba a buƙatar daidaita sigar magani a cikin marasa lafiya tare da gazawar ƙarancin ƙayyadadden matsakaici zuwa matsakaici. Ana ba da shawarar rufe aikin likita.
Marasa lafiya a Hadarin Hypoglycemia
A cikin marasa lafiya da ke cikin haɗarin haɓakar hypoglycemia (ƙarancin abinci mai gina jiki ko rashin daidaituwa, mummunan cuta ko raunin endocrine - damuwa da rashin ƙarfi, hypothyroidism, soke glucocorticosteroids (GCS) bayan tsawaita amfani da / ko gudanarwa a cikin manyan allurai, cututtukan zuciya mai tsanani. tsarin jijiyoyin jiki - mummunan cututtukan zuciya, mummunan carotid arteriosclerosis, atherosclerosis na kowa), ana bada shawara don amfani da mafi ƙarancin kashi (30 MG) na shirya ata Diabeton ® MV.

Yin rigakafin rikicewar cututtukan siga
Don cimma nasarar sarrafa glycemic mai ƙarfi, a hankali zaku iya ƙara yawan kwayar cutar Diabeton ® MV zuwa 120 mg / rana ban da abinci da motsa jiki don cimma burin HbA1c. Lura da hadarin kamuwa da cututtukan jini. Bugu da ƙari, sauran magungunan hypoglycemic, alal misali, metformin, alpha glucosidase nigibitor, wani abu mai mahimmanci na thiazolidinedione ko insulin, ana iya ƙara shi zuwa far.

Yara da matasa da ke ƙasa da shekara 18.
Ba a samun bayanai game da inganci da amincin miyagun ƙwayoyi a cikin yara da matasa masu shekaru 18 ba.

ADDU'AR SAUKI
Ganin ƙwarewa tare da gliclazide da sauran abubuwan da ake amfani da su na sulfonylurea, ya kamata a yi la’akari da waɗannan sakamako masu illa.
Hypoglycemia
Kamar sauran magunguna na ƙungiyar sulfonylurea, Diabeton ® MV na iya haifar da cutar rashin daidaituwa idan yanayin rashin abinci ne na daidaituwa kuma musamman idan aka rasa cin abincin. Bayyanar alamun alamomin hypoglycemia: ciwon kai, matsananciyar yunwar, tashin zuciya, matsananciyar wahala, karin yawan bacci, tashin hankali, tashin hankali, rashi hankali, rashi, damuwa, rudani, hangen nesa da magana, tashin hankali, tashin hankali, hangen nesa, hangen nesa. , farin ciki, rauni, rashi, bradycardia, delirium, gazawar numfashi, rashin bacci, asarar sani tare da yuwuwar ci gaba, na rashin nasara.
Hakanan za'a iya lura da halayen Andrenergic: ƙara yawan zufa, fata "m", damuwa, tachycardia, haɓakar jini, palpitations, arrhythmia, da angina pectoris.
A matsayinka na mai mulkin, ana dakatar da alamun hypoglycemia ta hanyar shan carbohydrates (sukari).
Shan masu zaki shine bashi da amfani. A cikin asalin wasu hanyoyin da aka samo asali na maganin sulfonylurea, an lura da komawar hypoglycemia bayan nasarar da ta samu.
A cikin tsananin rauni ko tsawan jini, ana nuna kulawa ta gaggawa akan likita, watakila tare da asibiti, koda kuwa akwai wani tasiri daga shan carbohydrates.

Sauran sakamako masu illa

Daga cikin jijiyoyin jiki: zafin ciki, tashin zuciya, amai, gudawa, maƙarƙashiya. Shan magungunan yayin karin kumallo yana hana waɗannan bayyanar cututtuka ko rage su.

Wadannan sakamako masu illa ba su da yawa:

A wani ɓangaren fata da ƙwayar fata mai ƙyalli: kurji, itching, urticaria, erythema, maculopapullous fyaɗe, tashin hankali mai ƙarfi.
Daga cikin tsarin jijiyoyin jini da jijiyoyin jini: cuta mai narkewa a jiki (anaemia, leukopenia, thrombocytopenia, granulocytopenia) ba su da yawa. A matsayinka na mai mulkin, waɗannan abubuwan mamaki ana iya juyawa idan an daina maganin jiyya.
A ɓangaren hanta da ƙwayar biliary: ƙara yawan aiki na enzymes "hanta" (aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase), hepatitis (lokuta mai raba). Idan cutar yolestice ta faru, yakamata a dakatar da maganin.

Sauran cututtukan da ke biyo baya yawanci ana iya juyawa idan an daina jinya.

Daga gefen bangaren hangen nesa: rikicewar gani na yau da kullun na iya faruwa saboda canji a cikin taro na jini, musamman a farkon farawa.
Abubuwan da ke haifar da sakamako masu illa ga asalin abubuwan sulfonylurea: yayin ɗaukar sauran abubuwan da ake buƙata na sulfonylurea, an lura da sakamako masu zuwa: erythrocytopenia, agranulocytosis, hemolytic anemia, pancytopenia, vasculitis rashin lafiyan da hyponatremia. An sami karuwa a cikin aikin “hanta” enzymes, hanta aiki na hanta (alal misali, tare da haɓakar cholestasis da jaundice) da cutar hepatitis, bayyanuwar ta ragu akan lokaci bayan dakatar da shirye-shiryen sulfonylurea, amma a wasu halayen haifar da gazawar hanta ga haɗari.

An gano tasirin sakamako a cikin gwaji na asibiti
A cikin binciken ADVANCE, an sami bambanci kaɗan a cikin tasirin mummunan yanayin haɗari tsakanin rukunin marasa lafiya biyu. Babu sabon bayanan aminci da aka karba. Smallaramin adadin marasa lafiya suna da cutar rashin ƙarfi na jini, amma ɗaukacin abin da ya faru na rashin ƙarfi zuwa ƙasa ya ragu. Halin da ke faruwa a cikin ƙwayar cuta mai ƙarfi ya kasance sama da ƙungiyar kula da glycemic misali. Yawancin bangarori na hypoglycemia a cikin rukunin kulawa na glycemic intanet an lura da su a kan tushen maganin kwantar da hankali na insulin.

SAURARA
Idan akwai abubuwan da ake amfani da su na abubuwan samo asali na sulfonylurea, toshewar hancin jini na iya bunkasa.
Idan kun sami alamun bayyanar cututtuka na hypoglycemia ba tare da tsinkaye mara kyau ko alamun cututtukan jijiyoyin jiki, ya kamata ku ƙara yawan ƙwayar carbohydrates tare da abinci, rage yawan ƙwayoyi da / ko canza abincin. Kusa da likita kwantar da hankali game da yanayin mai haƙuri ya kamata ya ci gaba har sai an sami tabbacin cewa babu abin da ke barazana ga lafiyarsa.
Wataƙila haɓaka yanayi mai rauni, tare da coma, tarko ko wasu rikicewar jijiyoyin jiki. Idan irin waɗannan bayyanar cututtuka sun bayyana, kulawar likita ta gaggawa da asibiti a cikin gaggawa suna da mahimmanci.
Game da matsalar rashin lafiyar hypoglycemic ko kuma idan ana tuhuma, ana yiwa mai haƙuri allurar ciki tare da 50 ml na maganin 20-30% na glucose. To, ana samar da maganin 10% na dextrose da aka sauke don kula da yawan hawan glucose na jini sama da 1 g / L. Dole ne a yi taka tsantsan da lura da tattarawar glucose na jini da saka idanu akan mara lafiya aƙalla awanni 48 masu zuwa.
Bayan wannan lokacin, dangane da yanayin haƙuri, likitan halartar ya yanke shawara game da buƙatar ƙarin sa ido. Dialysis ba shi da tasiri saboda ƙayyadadden ikon ɗaukar nauyin gliclazide zuwa ƙwayoyin plasma.

CIKIN SAUKI DA SAURAN LAFIYA
1) Magunguna masu haɓaka haɗarin hauhawar jini:
(haɓaka sakamakon gliclazide)
Abubuwan haɗin gwiwa
- Miconazole (tare da gudanarwa na tsari da kuma lokacin amfani da gel a kan mucosa na bakin): haɓaka tasirin hypoglycemic na gliclazide (hypoglycemia na iya haɓaka har zuwa coma).
Ba da shawarar haɗuwa ba
- Phenylbutazone (gudanarwa na tsari): haɓaka tasirin cutar hypoglycemic na abubuwan da suka samo asali na sulfonylurea (yana kawar da su daga sadarwa tare da sunadaran plasma da / ko yana rage jinkirin fita daga jiki).
Zai fi kyau a yi amfani da wani magani na kashe kumburi. Idan phenylbutazone ya zama dole, ya kamata a faɗakar da mai haƙuri game da buƙatar sarrafa glycemic. Idan ya cancanta, yakamata a daidaita sashi na maganin Diabeton ® MV a yayin da yake shan phenylbutazone da kuma bayan sa.
- Ethanol: yana haɓaka haɓakar jini, zai iya haɓaka halayen sakamako na sakamako, na iya ba da gudummawa ga haɓakar ƙwaƙwalwar ƙwayar cuta. Wajibi ne a ƙi shan magunguna, waɗanda suka haɗa da ethanol da barasa.
Kariya
Gliclazide a hade tare da wasu kwayoyi (alal misali, sauran wakilai na hypoglycemic - insulin, alpha glucosidase inhibitor, biguanides, beta-blockers, fluconazole, angiotensin-canza enzyme inhibitors - captopril, enalapril, H2S-histamine inhibitors, non-histamine inhibitors magungunan rigakafin kumburi) yana haɗuwa tare da haɓaka tasirin cutar hypoglycemic da haɗarin hauhawar jini.
2) Magungunan da ke haɓaka glucose na jini:
(raunana sakamakon gliclazide)
Ba da shawarar haɗuwa ba
- Danazole: yana da sakamako masu ciwon sukari. Idan shan wannan magani ya zama dole, ana bada shawara ga mai haƙuri da hankali glycemic iko. Idan ya cancanta, haɗin gwiwa na magunguna, ana ba da shawarar cewa an zaɓi kashi na wakili na hypoglycemic duka a lokacin mulkin danazol da kuma bayan an cire shi.
Kariya
- Chlorpromazine (antipsychotic): A cikin allurai masu yawa (sama da 100 MG kowace rana) yana ƙaruwa da haɗuwar glucose a cikin jini, yana rage ɓoyewar insulin.
Anyi shawarar kulawa da hankali glycemic. Idan ya zama dole a sha magunguna tare, ana bada shawara cewa an zabi wani kashi na hypoglycemic wakili, duka biyu a lokacin antipsychotic da bayan cirewa.
- SCS (aikace-aikacen tsari da na gida: intraarticular, fata, gudanarwar shugabanci): ƙara yawan haɗarin glucose jini tare da yiwuwar ci gaban ketoacidosis (raguwa da haƙuri ga carbohydrates). Ana ba da shawarar kula da hankali sosai, musamman a farkon jiyya. Idan ya zama dole don shan kwayoyi tare, za a buƙaci daidaitawar kashi na wakilin hypoglycemic duka yayin gudanar da GCS da kuma bayan an cire su.
- Ritodrin, salbutamol, terbutaline (gudanarwa na ciki): beta-2 adrenergic agonists yana ƙara yawan haɗarin glucose na jini.
Dole ne a saka kulawa ta musamman akan mahimmancin sarrafa kwayar cutar glycemic. Idan ya cancanta, ana bada shawara don canja wurin mai haƙuri zuwa maganin insulin.
3) Haɗe-haɗe da za'ayi la'akari dasu
- Anticoagulants (misali warfarin)
Abubuwan da keɓaɓɓe na sulfonylureas na iya haɓaka tasirin maganin anticoagulants lokacin ɗauka tare. Ana iya buƙatar daidaita sakin Anticoagulant.

LITTAFIN KWARAI
Hypoglycemia
Lokacin ɗaukar magungunan sulfonylurea, gami da gliclazide, hypoglycemia na iya haɓakawa, a wasu yanayi a cikin mummunan yanayi da tsawan lokaci, ana buƙatar asibiti da kulawa da jijiyoyin ƙwayar dextrose na kwanaki da yawa (duba sashin "Abubuwan sakamako").
Za'a iya ba da magani ga wajan marasa lafiya waɗanda abincinsu na yau da kullun kuma sun haɗa da karin kumallo. Yana da mahimmanci a kula da isasshen ƙwayar carbohydrates tare da abinci, tun da haɗarin haɓakar haɓaka na haɓaka tare da abinci mai daidaituwa ko rashin isasshen abinci, tare da abinci wanda ba shi da kyau a cikin carbohydrates.
Hypoglycemia sau da yawa yana haɓaka tare da rage cin abinci mai kalori, bayan tsawanta ko motsa jiki mai ƙarfi, bayan shan magungunan ethanol ko ethanol dauke da kwayoyi, ko lokacin shan magunguna na hypoglycemic da yawa a lokaci guda.
Yawanci, alamun hypoglycemia yana ɓacewa bayan cin abinci mai abinci mai kyau a cikin carbohydrates (kamar sukari). Ya kamata a ɗauka cikin tunanin cewa shan masu zaƙi ba zai taimaka wajen kawar da alamun cututtukan zuciya ba. Kwarewar amfani da wasu abubuwan da ake amfani da su na sulfonylurea suna nuna cewa hypoglycemia na iya dawowa duk da tasirin farko na wannan yanayin. Idan yanayin bayyanar cututtuka na hypoglycemic an furta ko suna daɗewa, har ma a cikin yanayin ci gaba na ɗan lokaci bayan cin abinci mai cike da ƙwayoyin carbohydrates, kulawa ta gaggawa ta zama tilas, har zuwa asibiti.
Don guje wa ci gaban hypoglycemia, zaɓin zaɓi na mutum da hankali da kuma hanyoyin yin magani ya zama dole, kazalika da samar wa mara lafiya cikakken bayani game da magani.
Increasedarin haɗarin hauhawar jini na iya faruwa a waɗannan lamari:

ƙi ko rashin haƙuri na marasa lafiya (musamman tsofaffi) don bi abubuwan da likitocin suka rubuta don duba yanayinsa,
karancin abinci mai gina jiki, rashin abinci mai gina jiki, azumi da kuma rage cin abincin,
rashin daidaituwa tsakanin aiki na jiki da kuma adadin carbohydrates,
na gazawar
mai tsanani hanta
yawan shan magani na masu ciwon sukari ® MV,
wasu rikice-rikice na endocrine: cutar ta thyroid, pituitary da adrenal insufficiency,
Lokaci guda na amfani da wasu magunguna (duba sashe "hulɗa tare da wasu kwayoyi"). Bayyanar bayyanar cututtuka na hypoglycemia za a iya rufe shi lokacin ɗaukar beta-blockers, clonidine, reserpine, guanethidine.

Renal da hanta ta gaza
A cikin marasa lafiya da ke fama da hepatic da / ko gazawar ƙoshin koda, ƙwayar magunguna da / ko kaddarorin magungunan gliclazide na iya canzawa.
Halin hypoglycemia wanda ke tasowa a cikin irin waɗannan marasa lafiya na iya zama daɗewa sosai, a cikin irin waɗannan halayen, likita na dacewa ya zama dole.

Bayanai mara haƙuri
Wajibi ne a sanar da mara lafiya, da kuma dangin sa, game da hadarin kamuwa da cutar sankarar mahaifa, alamunta da kuma yanayin da ke kawo ci gabanta. Dole ne a sanar da mara lafiya game da haɗarin haɗari da fa'idojin magani da aka gabatar.
Marasa lafiya yana buƙatar bayyana mahimmancin cin abinci, buƙatar motsa jiki na yau da kullun da saka idanu akan yawan haɗuwar glucose jini.
Rashin sarrafa glucose na jini
Gudanar da cutar ta glycemic a cikin marasa lafiya da ke karɓar maganin cututtukan cututtukan jini na iya zama mai rauni a cikin waɗannan maganganu: manyan ayyukan tiyata da raunin da ya faru, ƙonewa mai yawa, cututtuka masu kamuwa da cututtukan febrile. Tare da waɗannan yanayin, yana iya zama mahimmanci don dakatar da jiyya tare da miyagun ƙwayoyi Diabeton ® MV kuma a tsara maganin insulin.
A cikin wasu marasa lafiya, tasirin wakilai na hypoglycemic na bakin mutum, gami da gliclazide, yana jin daɗin raguwa bayan dogon magani. Wannan tasiri na iya zama saboda ci gaban cutar da raguwa a cikin maganin warkewa da magunguna. An san wannan tasiri a matsayin maganin juriya na biyu, wanda dole ne a bambanta shi da na farko, wanda magani bai ba da sakamako na asibiti da ake tsammanin riga a wa’adin farko. Kafin bincikar mai haƙuri tare da juriya na miyagun ƙwayoyi, ya zama dole don kimanta ƙimar zaɓi na zaɓi da kuma yardawar haƙuri tare da abincin da aka tsara.

Gwajin Lab
Don tantance iko na glycemic, ana bada shawarar ƙuduri na yau da kullun na yawan zubar da jini a cikin jini da kuma ƙwaƙwalwar ƙwayar haemoglobin HbA1c. Bugu da kari, yana da kyau a rika gudanar da aikin kai-da-kai game da yawan kwantar da hankali na glucose na jini.
Abubuwan da ke cikin Sulfonylurea na iya haifar da cutar haemolytic a cikin marasa lafiya da raunin glucose-6-phosphate dehydrogenase. Tunda gliclazide wani abu ne wanda ya samo asali na sulfonylurea, dole ne a kula da shi yayin gudanar da shi ga marasa lafiya da raunin glucose-6-phosphate dehydrogenase.
Zai yiwu a kimanta yiwuwar rubuta kwayar cutar ƙwaƙwalwar ƙwayar cuta ta wata ƙungiyar.

CIGABA DA RUWAN DADA CAR DA CIKIN AIKATA DA AIKATA DA AIKATA DA AIKATA DA AIKATA DA AIKATA
Marasa lafiya yakamata su lura da alamun cututtukan hypoglycemia kuma yakamata suyi hankali lokacin tuki ko aiwatar da aiki suna buƙatar ƙimar yawan motsa jiki da tunani, musamman a farkon farfaɗo.

MAGANIN YANZU
30 MG Allunan an sake sakin allunan
Allunan 30 a cikin kumburi (PVC / Al), blister 1 ko 2 tare da umarnin amfani da magani a cikin kwali.
Lokacin da marufi (marufi) a kamfanin Rasha LLC Serdix: Allunan 30 a cikin kumburi (PVC / Al), blister 2 tare da umarnin don amfani a akwatin kwali.

HUKUNCIN SAURARA
Ba a buƙatar yanayi na ajiya na musamman.
Ayi nesa da isar yara.
Jerin B.

RAYUWAR SHI
Shekaru 3 Kada kayi amfani bayan ranar karewa wanda aka nuna akan kunshin.

HANYAR BAYANIN
Da takardar sayan magani.

Takaddun rajista da aka samar ta Servier Laboratories, Faransa

An samar da shi daga Kamfanin Masana'antu na Servier Industry Lab, Faransa
"Laboratories Servier masana'antu":
905, Saran babbar hanyar, 45520 Gidey, Faransa
905, hanya de Saran, 45520 Gidy, Faransa

Ga duk tambayoyin, tuntuɓi ofishin Wakilin Hukumar JSC “Servier Laboratory”.

Wakilcin JSC “Laboratory Servier”:
115054, Moscow, Paveletskaya pl. d.2, shafi 3

Serdix LLC:
142150, Rasha, Yankin Moscow,
Podolsky gundumar, ƙauyen Sof'ino, shafi 1/1

Takaddun rajista da aka samar ta Servier Laboratories, Faransa
Buga daga: Serdix LLC, Russia
Serdix LLC:
142150, Rasha, Yankin Moscow,
Podolsky gundumar, ƙauyen Sof'ino, shafi 1/1
Ga duk tambayoyin, tuntuɓi ofishin Wakilin Hukumar JSC “Servier Laboratory”.

Wakilcin JSC “Laboratory Servier”:
115054, Moscow, Paveletskaya pl. d.2, shafi 3