Analogs na langerin miyagun ƙwayoyi

Langerin yana ɗayan magunguna masu yawa waɗanda ake amfani da su don magance tsarin ilimin da ake kira mellitus-non-insulin-dogara da ciwon sukari mellitus. Magungunan yana daga cikin rukunin magunguna na biguanide, babban tasiri wanda shine rage buƙatar samar da insulin.

Farashin Langerin a cikin magunguna, dangane da adadin da ake buƙata, na iya kasancewa daga ɗari ɗari zuwa ɗari uku rubles.

Langerin magani ne na baka wanda aka yi amfani dashi a cikin hadaddun maganin ciwon sukari. Babban abincinta shine metformin abu. Magungunan yana ɗayan magunguna masu rage sukari kuma ana amfani dashi sau da yawa don daidaita matakan sukari na jini a cikin masu ciwon sukari.

Ofayan ɗayan magunguna masu yiwuwar irin wannan maganin shine gudanarwarsa dangane da rashin aiki na allunan da aka yi amfani dasu a baya daga ƙungiyar sulfonylurea. Bugu da kari, kiba babbar matsala ce ta saduwa ga duk mutanen da ke dauke da ciwon sukari.

Abin da ya sa, Langerin ya ba da damar rage yawan sukari kawai, amma yana ba da gudummawa ga jinkirin daidaita ƙimar haƙuri.

Kayan magani da alamomi don amfani

Hanyar aiwatar da aikin babban maganin yana da alaƙa da iyawarta don dakatar da ayyukan gluconeogenesis, kazalika da ayyukan ƙaddamar da mayukan kitse kyauta da hadawar iskar shaƙa. Wani wakilin aji na biguanide ba ya shafar adadin insulin da aka saki a cikin jini, amma yana canza magungunansa ta hanyar rage yawan haɗarin insulin da ƙura da kuma ƙara yawan adadin insulin zuwa proinsulin.

Batu mai mahimmanci a cikin aikin aiwatar da irin waɗannan allunan shine ƙarfafa haɓakar glucose ta ƙwayoyin tsoka.

Babban mahimmancin amfani da magani shine haɓakar kamuwa da cutar insulin-a cikin mutum, musamman tare da rashin daidaituwa ga abincin da aka bi.

Babban kaddarorin magunguna na Langerin sun haɗa da:

• yana rage adadin haemoglobinꓼ glycated
• neutralizes juriya insulin Kwayoyin zuwa hormone insulin
• yana da kyau yana tasiri daidaitaccen bayanin furotin na jini plasmas
• rage mummunan cholesterolꓼ

Bugu da ƙari, yin amfani da miyagun ƙwayoyi zai iya daidaita nauyin jikin mutum.

Umarnin don amfani da allunan

Ana amfani da maganin miyagun ƙwayoyi Langerin a cikin nau'ikan allunan da aka rufe.

Allunan an cika su a cikin jaka na filastik, wanda aka rufe tare da tsare tsare na aluminium.

An sanya fakitoci a cikin kwali mai kwali tare da umarnin don amfani da miyagun ƙwayoyi.

Dogaro da maganin da ake buƙata na maganin da aka yi amfani da shi, ana iya siyan magani tare da sashi na:

1. Miliyan 500.
2. Milligrams 850.
3. Graaya daga cikin gram na abu mai aiki.

Hanyar shan allunan magana ce ta baki, lokacin cin abinci ko bayan sa. Likitocin da ke halartar sun wajaba a bayar da magani ga kowane mai haƙuri daban-daban dangane da tsananin cutar. Hakanan, ƙwararren likita ya ƙayyade yawan adadin magunguna yayin rana.

Umarnin-Langerin don amfani yana bada shawarar fara aikin warkewa tare da mafi karancin sashi na 500 MG na kayan aiki. Yawan allurai na maganin a lokacin zai iya zama daga daya zuwa uku. A hankali, za a iya ƙara yawan zuwa 850 MG na ƙwayar abu mai aiki a cikin yini (sau ɗaya sau biyu a rana). Likita mai halartar yana lura da yanayin haƙuri kuma, ba fiye da sau ɗaya a mako ba, yana daidaita adadin maganin da aka karɓa a sama.

Hakanan an wajabta magungunan don magance cutar a cikin yara sama da shekaru goma. Monotherapy ya kamata ya fara da sashi na 500 MG na kayan aiki sau ɗaya ko sau biyu a rana. Bayan wani lokaci, an ba da izinin ci gaba na digiri a cikin ƙwayoyi, amma ba fiye da gram biyu a rana ba, an kasu kashi biyu zuwa uku.

Yawanci, canji a cikin yawan ƙwayoyi yana faruwa bayan kwanaki goma zuwa goma sha biyar dangane da sakamakon gwajin jini don matakin glucose.

A wasu halaye, shirye-shiryen kwamfutar hannu wani ɓangare ne na haɗin maganin tare da injections na insulin.

Ya kamata a lura cewa an gudanar da kulawa ta lokaci guda na Langerin tare da insulin, abubuwan da ake amfani da su na sulfonylurea, acarbose, ko ACE inhibitors don haɓaka tasirin hypoglycemic na magungunan.

A wasu halaye, likita mai halartar na iya maye gurbin amfani da Langerin tare da Allunan irin wannan abun da ke ciki. A yau, akwai manyan adadin magunguna, babban sinadaran aiki wanda shine metformin.

Farashin magungunan analog na iya bambanta sosai, gwargwadon kamfanin da ke kera magunguna.

Waɗanne abubuwa suke amfani da su?

Ba daidai ba da aka zaɓa sashi ko rashin jituwa tare da shawarwarin likitocin da ke halartar na iya haifar da bayyanar da martanin cutar yayin shan maganin.

Bugu da ƙari, akwai lokuta waɗanda aka haramta amfani da magani a kan metformin.

Umarnin don amfani da miyagun ƙwayoyi yana nuna jerin manyan abubuwan hana haihuwa.

Babban sabbin hanyoyin amfani da allunan ta Langerin sun hada da masu zuwa:

• matsanancin rauni na hanta ko aikin koda, karancinsu ꓼ
• giya, ciki har da na kullum formꓼ
• zuciya ko rashin numfashiꓼ
• m rashin ƙarfi infarctionꓼ
• yanayin cutar rashin lafiyan cuta ko asalinsu
• ci gaba da ciwon sukari ƙafa ciwoabet
• a gaban rashin haƙuri ga metformin da haɓakar halayen rashin lafiyan jijiyoyin
• kasancewar kamuwa da cututtukaꓼ
• azumi tare da ciwon sukari ko bin wani abincin wanda abincinsa na yau da kullun bai wuce kilocalories dubu ba
• kafin da bayan tiyataꓼ
• tare da raunin kwanan nan mai rauniꓼ
• kafin da bayan binciken da suke amfani da isotropes na aidin iodineꓼ
• ketoacidosis da lactic acidosis.

Bugu da kari, mata bai kamata su sha maganin ba yayin daukar ciki da lactation.

Aukuwa na sakamako masu illa na iya bayyana kansa ga wani bangare na jikin mutum daban - tsarin gastrointestinal fili, metabolism, tsarin zuciya da jijiyoyin fata. Babban mummunan halayen da zai iya faruwa sakamakon shan magungunan sune:

1. Haske mai ƙanshi. Wani lokacin tashin zuciya yana faruwa a cikin nau'in ciwon sukari na 2. Ana iya maye gurbin tashin hanci ta amai
2. Nau'in ciki mai raɗaɗi.
3. Bayyanar ɗanɗano mai ƙarfe a cikin rami na baka.
4. Hematopoiesis da hemostasis.
5. Megaloblastic anemia.
6. Rage sukari na jini a matakin da aka yarda - hypoglycemia.
7. Fitowar rauni a jiki.
8. Damuwa.
9. Hypotension.
10. Rashin lafiyar numfashi.
11. Bayyanar cututtukan fata ko fatar kan fata.

Ya kamata a kula da hankali yayin shan Langerin tare da wasu magunguna. Yin amfani da allunan a lokaci guda tare da cymeditine yana ƙara haɗarin lactic acidosis. Haɗarin Langerin tare da madaukai na madaidaici na iya haifar da sakamako iri ɗaya. A wannan yanayin, ban da yiwuwar bayyana lactic acidosis, ana iya lura da wata alama ta gazawar koda.

Yin amfani da miyagun ƙwayoyi, ya zama dole don saka idanu kan aikin al'ada na kodan da kuma ƙayyade adadin lactate a cikin plasma aƙalla sau biyu a shekara.

Bayanai game da kwayoyi da aka yi amfani da su don magance cututtukan sukari an bayar dasu a cikin bidiyon a wannan labarin.

Bayanin maganin

Langerine - wakilin mahaifa na baka daga rukunin biguanides (dimethylbiguanide). Hanyar aiwatar da metformin yana da alaƙa da iyawarta don dakatar da gluconeogenesis, kazalika da samuwar ƙwayoyin mai mai kyauta da hadawar hada hada abubuwa da hada abubuwa da kitse na mai. Theara hankalin mai karɓar mahaifa zuwa insulin da kuma amfani da glucose ta sel. Metformin baya tasiri da yawan insulin a cikin jini, amma yana canza magunguna ta hanyar rage ragin insulin da za'a ɗauka kyauta da kuma ƙara yawan rabo daga insulin zuwa proinsulin.

Metformin yana ƙarfafa haɗin glycogen ta hanyar yin aiki akan glycogen synthetase. Capacityara ƙarfin jigilar kayayyaki na kowane nau'ikan jigilar jini na membrane. Yana jinkirta ɗaukar ciki na glucose.

Yana rage matakin triglycerides, LDL, VLDL. Metformin yana haɓaka ƙirar fibrinolytic ta jini ta hanyar dakatar da nau'in mai kunnawa mai hana jini plasminogen.

Yayin shan metformin, nauyin jikin mai haƙuri ko dai ya kasance tsayayye ko yana raguwa da matsakaici.

Jerin analogues

Labari mai ban sha'awa

Yadda zaka zabi analog ɗin da ya dace
A fannin ilimin magunguna, yawanci ana rarraba magunguna zuwa maganganu da analogues. Tsarin kalmomin sun hada da ɗaya ko fiye da waɗannan ƙwayoyin aiki guda ɗaya waɗanda ke da tasirin warkewa akan jiki. Ta hanyar analogs ana nufin magunguna waɗanda ke ɗauke da abubuwa daban-daban na aiki, amma anyi nufin maganin cututtukan guda ɗaya.

Bambanci tsakanin kamuwa da kwayar cuta da kwayan cuta
Kwayoyin cuta suna haifar da ƙwayoyin cuta, ƙwayoyin cuta, fungi da protozoa. Halin cututtukan da ƙwayoyin cuta da ƙwayoyin cuta ke haifar da irin wannan. Koyaya, don bambance abin da ke haifar da cutar yana nufin zaɓi ainihin magani wanda zai taimaka wajan magance cutar da sauri kuma ba zai cutar da yaron ba.

Cutar rashin lafiyan shine sanadiyyar yawan sanyi
Wasu mutane sun saba da yanayin da yaro sau da yawa kuma na dogon lokaci yana fama da mura. Iyaye suna kai shi wurin likitoci, yin gwaje-gwaje, shan magunguna, kuma a sakamakon haka, an riga an yiwa yaro rajista tare da likitan yara yayin da yake rashin lafiya. Ba a gano ainihin abubuwan da ke haifar da cututtukan numfashi ba.

Urology: lura da chlamydial urethritis
Chlamydial urethritis yawanci ana samun sa a cikin aikin masanin ilimin urologist. Ana haifar dashi ta hanyar Chlamidia trachomatis mai aiki da jijiya, wanda ke da ƙirar ƙwayoyin cuta da ƙwayoyin cuta, wanda yawanci yana buƙatar jigilar maganin rigakafi na dogon lokaci don maganin ƙwayoyin cuta. Yana da ikon haifar da kumburin da baya takamaiman cutar kumburi a cikin maza da mata.

Langerin - umarnin don amfani, farashin, sake dubawa

Shafin yana ba da bayani game da magungunan Langerin - an gabatar da umarnin cikin fassarar kyauta. Don ƙarin ingantaccen bayani, da fatan za a duba bayanin masana'anta. Akwai umarnin don magunguna ba dalilai ne na magani ba.

Masu kera: Zentiva a.s (Slovak Republic)

Abubuwa masu aiki
Class of cututtuka

• Mellitus na rashin insulin-da ke fama da cutar kansa

Clinical da kungiyar magunguna

• Ba a kayyade ba. Duba umarnin

Aikin magunguna
Kungiyar magunguna

• Hypoglycemic roba da sauran jami'ai a cikin haɗuwa

Saki nau'i na miyagun ƙwayoyi Langerin

500 MG filinda kwalayen tabarau, bliri fakitin fakitin 10 na kwali 6 fakiti, 500 MG mai hade da allunan, blister fakitin 10 fakitin 10 fakitin kwali 3, 500 Allunan mai rufin fim, blister fakitin fakitin 10 na kwali 9, kwayoyin hana daukar ciki, 850 MG-mai rufin fim, blister fakitin fakitin 10 na kwali 6, Allunan, 850 MG-mai rufin blister fakitin, 850 MG fil blister fakiti, 10 fakitin kwali fakitin 3, allunan da aka rufe fim 850 MG, bugu da bakin ciki 10 fakitin kwali 9, Allunan mai rufi tare da fim mai rufi 1 g, blister fakiti 10 fakitin kwali 1, Allunan mai rufi da fim harsashi 1 g, blister marufi 10 fakitin kwali 3, Allunan mai rufi da fim harsashi 1 g, blister fakiti 10 fakitin kwali 9,

Allunan mai rufi tare da fim mai rufin of 1 g, blister marufi 10 fakiti kwali 6,

Pharmacodynamics

Yana rage taro na glucose (a kan komai a ciki kuma bayan cin abinci) a cikin jini da kuma matakin glycosylated haemoglobin, yana ƙara haƙuri. Yana rage shanyewar hanji a cikin hanta, haɓakar sa a cikin hanta, ƙin ƙwaƙwalwar insulin a cikin ƙwayoyin mahaifa (haɓakar glucose da haɓakar metabolism).

Shin, ba ya canza ɓoye insulin ta hanyar ƙwayoyin beta na tsibirin pancreatic (matakan insulin akan ƙasan ciki kuma amsar insulin yau da kullun na iya raguwa).

Yana daidaita tsarin lipspros na jini a cikin marasa lafiya da marasa lafiyar insulin-da ke fama da rashin lafiyar insellus: yana rage abun ciki na triglycerides, cholesterol da LDL (wanda aka ƙaddara akan komai a ciki) kuma baya canza matakan lipoproteins na wasu ƙarancin yawa. Yanke ko rage karfin jiki.

Pharmacokinetics

Da sauri ya daga hanjin narkewa. Cikakken bioavailability (a kan komai a ciki) shine 50-60%. Cmax a cikin plasma an kai shi bayan sa'o'i 2. Cin abinci mafi ƙarancin Cmax da 40% kuma yana rage jinkirin nasa ta minti 35.

Daidaita ma'aunin metformin a cikin jini ya kai cikin awa 24 zuwa 48 bai wuce 1 μg / ml ba. Ofimar rarraba (don guda ɗaya na 850 MG) shine (654 ± 358) l. Da kyar aka ɗaura nauyin garkuwar plasma, ya sami damar tarawa a cikin glandan ciki, hanta da kodan.

An cire ta da kodan (galibi ta hanyar toshewa) ba a canzawa ba (90% a rana). Renal Cl - 350-550 ml / min. T1 / 2 shine 6.2 h (plasma) da 17.6 h (jini) (banbanci yana faruwa ne saboda iyawar cumul a cikin sel jini).

A cikin tsofaffi, T1 / 2 yana tsawaita kuma Cmax yana ƙaruwa. Game da lalacewa aiki na renal, T1 / 2 tsawanta da tsayayyen keɓaɓɓen raguwa.

A lokacin jiyya kamata ya daina shayarwa.

Contraindications

Hypersensitivity, cutar koda, ko gazawar renal (matakan creatinine sun fi 0.132 mmol / L cikin maza da 0.123 mmol / L a cikin mata), mummunan lalata hanta, yanayi tare da hypoxia (ciki har da

gazawar zuciya da rashin karfin numfashi, matsanancin lokaci na rauni na myocardial infarction, m cerebrovascular insufficiency, anemia), rashin ruwa, cututtukan da ke tafe, yawan aiki da raunin da ya faru, barasa mai guba, matsanancin cuta ko rashin lafiyar koda, wanda ya hada da ketoacidosis mai ciwon sukari tare da ko ba tare da coma ba, tarihin lactic acidosis bijiro da tsarin karancin kalori (kasa da 1000 kcal / day), bincike ta amfani da isotopes na iodine na rediyoakti, ciki, shayarwa.

Side effects

Daga narkewar abinci: a farkon hanya na jiyya - anorexia, zawo, tashin zuciya, amai, flatulence, ciwon ciki (raguwa da abinci), dandano mai ƙarfe a bakin (3%).

Daga gefen tsarin jijiyoyin jini da jini (hematopoiesis, hemostasis): a cikin mafi yawan lokuta - megaloblastic anemia (sakamakon malabsorption na bitamin B12 da folic acid).

Daga gefen metabolism: hypoglycemia, a cikin lokuta mafi wuya - lactic acidosis (rauni, rashin barci, hypotension, bradyarrhythmia mai tsayayya, rikicewar numfashi, zafi na ciki, myalgia, hypothermia).

Daga fata: kurji, dermatitis.

Yin hulɗa tare da wasu kwayoyi

Sakamakon metformin yana raunana ta hanyar thiazide da sauran diuretics, corticosteroids, phenothiazines, glucagon, hormones thyroid, estrogens, ciki har da kamar yadda wani bangare na hana hana daukar ciki, phenytoin, acid nicotinic, sympathomimetics, antagonists na alli, isoniazid.

A cikin kashi ɗaya a cikin masu sa kai masu lafiya, nifedipine ya karɓi sha, Cmax (20%), AUC (9%) metformin, Tmax da T1 / 2 basu canza ba. Tasirin hypoglycemic yana haɓaka ta insulin, abubuwan da suka samo asali na sulfonylurea, acarbose, NSAIDs, MAO inhibitors, oxytetracycline, ACE inhibitors, abubuwan ƙira na clofibrate, cyclophosphamide, beta-blockers.

Nazarin yin hulɗa guda ɗaya a cikin masu ba da agaji na lafiya ya nuna cewa furosemide yana ƙaruwa Cmax (da kashi 22%) da AUC (da kashi 15%) na metformin (ba tare da manyan canje-canje a cikin izinin fitowar na metformin ba), metformin yana rage Cmax (da kashi 31%), AUC (da 12 %) da T1 / 2 (32%) na furosemide (ba tare da manyan canje-canje ba game da karɓar furosemide na yara).

Babu bayanai game da hulɗa da metformin da furosemide tare da amfani na tsawan lokaci. Magunguna (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren da vancomycin) sun ɓoye a cikin tubules suna gasa don tsarin jigilar tubular kuma suna iya haɓaka Cmax na metformin da 60% tare da tsawan magani.

Cimetidine yana rage jinkirin kawar da metformin, wanda ke kara haɗarin haɓakar lactic acidosis. Rashin jituwa tare da barasa (ƙarancin haɗarin haɓakar madara acidosis).

Ya kamata a sa ido a kan aikin fyaɗe, yin ɗamara, da kuma glucose jini. Musamman saka idanu sosai kan matakan glucose na jini ya zama dole yayin amfani da metformin a hade tare da sulfonylureas ko insulin (haɗarin hypoglycemia).

Ya kamata a gudanar da magani tare da metformin da insulin a asibiti har sai an samar da isasshen kashi na kowane magani. A cikin marasa lafiya a kan ci gaba da jiyya tare da metformin, ya zama dole don ƙayyade abubuwan da ke cikin bitamin B12 sau ɗaya a shekara saboda yuwuwar rage ƙarfin sha.

Wajibi ne don tantance matakin lactate a cikin plasma aƙalla sau 2 a shekara, kuma tare da bayyanar myalgia. Tare da karuwa a cikin abubuwan lactate, an soke maganin.

Kada kuyi amfani dasu kafin aikin tiyata da kuma cikin kwanaki 2 bayan an yi su, haka kuma cikin kwanaki 2 kafin da bayan gwajin gwaji (introvenous urography, angiography, da sauransu).

Tsarin saki, abun da aka shirya da marufi

10 inji mai kwakwalwa - blisters (3) - fakitoci na kwali. - blisters (6) - fakitoci na kwali.

10 inji mai kwakwalwa - blister (9) - fakitoci na kwali.

Aikin magunguna

Wakili hypoglycemic wakili daga rukuni na biguanides (dimethylbiguanide). Hanyar aiwatar da metformin yana da alaƙa da iyawarta don dakatar da gluconeogenesis, kazalika da samuwar ƙwayoyin mai mai kyauta da hadawar hada hada abubuwa da hada abubuwa da kitse na mai.

Metformin baya tasiri da yawan insulin a cikin jini, amma yana canza magunguna ta hanyar rage ragin insulin da za'a ɗauka kyauta da kuma ƙara yawan rabo daga insulin zuwa proinsulin.

Haɗi mai mahimmanci a cikin tsarin aikin metformin shine ƙarfafa motsa jini daga ƙwayoyin tsoka.

Metformin yana haɓaka wurare dabam dabam na jini a cikin hanta kuma yana haɓaka juyar da glucose zuwa glycogen. Yana rage matakin triglycerides, LDL, VLDL. Metformin yana haɓaka ƙirar fibrinolytic ta jini ta hanyar dakatar da nau'in mai kunnawa mai hana jini plasminogen.

Nau'in 1 na ciwon sukari mellitus (wanda ke dogara da insulin) - tare da burin rage buƙatar insulin da hana karuwar nauyi (ƙari ga ilimin insulin).

Nau'in 2 na ciwon sukari mellitus (wanda ba shi da insulin-ba) a yanayin rashin abinci mai ƙoshin abinci (musamman kiba).

Sakawa lokacin

Ga marasa lafiya da basa karbar insulin, a cikin kwanakin 3 na farko - 500 mg sau 3 / rana ko 1 g 2 sau / rana yayin ko bayan abinci. Daga rana ta 4 zuwa rana ta 14 - 1 g sau 3 / rana. Bayan rana ta 15, ana daidaita sashin shan la'akari da matakin glucose a cikin jini da fitsari. Adadin kulawa shine 100-200 mg / rana.

Tare da yin amfani da insulin a lokaci daya a cikin ƙarancin ƙasa da raka'a 40 / rana, tsarin kulawa na metformin iri ɗaya ne, yayin da za a iya rage yawan insulin a hankali (ta hanyar raka'a 4-8 a kowace rana). Idan mai haƙuri ya sami fiye da raka'a 40 / rana, to, yin amfani da metformin da raguwa a cikin adadin insulin yana buƙatar kulawa sosai kuma ana gudanar da shi a asibiti.

Analogs da farashin magungunan Langerin

Allunan mai rufe fim

Allunan mai rufe fim

Allunan mai rufe fim

Allunan mai rufi

Ci gaba da sakin allunan

Ci gaba da sakin allunan

Allunan mai rufe fim

Allunan mai rufe fim

Allunan mai rufe fim

Allunan mai rufe fim

Allunan mai rufe fim

tauraron dan adam mai cikakken nauyin fim

Ci gaba da sakin allunan

Ci gaba da sakin allunan

Allunan mai rufe fim

Jimlar kuri'un: likitoci 73.

Cikakkun bayanai na masu amsa ta hanyar kwarewar:

Side sakamako

Daga tsarin narkewa: mai yiwuwa (yawanci a farkon jiyya) tashin zuciya, amai, zawo.

Daga tsarin endocrine: hypoglycemia (galibi lokacin amfani da allurar da ba ta dace ba).

Daga gefen metabolism: a wasu halaye - lactic acidosis (yana buƙatar dakatar da magani).

Daga tsarin hawan jini: a wasu halaye - megaloblastic anemia.

Umarni na musamman

Ba'a bada shawara ga cututtukan m, daɗaɗɗar cututtukan cututtukan fata da cututtukan kumburi, raunin da ya faru, cututtukan tiyata, da haɗarin rashin ruwa.

Kada ayi amfani dasu kafin aikin tiyata kuma cikin kwanaki 2 bayan an yi su.

Ba'a ba da shawarar yin amfani da metformin a cikin marasa lafiya fiye da shekaru 60 da waɗanda ke yin aiki na zahiri, wanda ke da alaƙa da haɓakar haɓakar lactic acidosis.

Lokacin yin jiyya, ya zama dole don saka idanu akan aikin renal, ƙuduri na abubuwan lactate a cikin plasma ya kamata a aiwatar da su aƙalla sau 2 a shekara, kuma tare da bayyanar myalgia.

Za'a iya amfani da Metformin a hade tare da sulfonylureas. A wannan yanayin, musamman saka idanu na matakan glucose na jini ya zama dole.

Yin amfani da metformin a matsayin wani ɓangare na maganin haɗin gwiwa tare da insulin ana bada shawarar a asibiti.

Hulɗa da ƙwayoyi

Tare da yin amfani da lokaci guda tare da abubuwan da aka samo na sulfonylurea, acarbose, insulin, salicylates, MAO inhibitors, oxygentetracycline, ACE inhibitors, tare da clofibrate, cyclophosphamide, tasirin hypoglycemic na metformin na iya inganta.

Tare da yin amfani da lokaci guda tare da GCS, hana rigakafin hormonal don sarrafawa na baka, adrenaline, glucagon, hormones thyroid, abubuwan da ke tattare da kwayoyin halittar thiazide, abubuwan da aka samo na nicotinic acid, raguwar tasirin hypoglycemic na metformin mai yiwuwa ne.

Amfani da cimetidine na iya ƙara haɗarin lactic acidosis.

37. : 2.92)
Ana lodawa ...

Umarnin LANGERIN (LANAGERIN)

Lambar ATX: A10BA02

Ana amfani da Metformin daga narkewa. Cmax a cikin plasma an kai shi kimanin awa 2 bayan shigowa. Bayan awanni 6, cirewar daga cikin jijiyoyin mahaifa zai kare kuma yaduwar metformin a cikin plasma sannu a hankali Hakanan bashi da alaqa da sunadaran plasma. Yana tarawa a cikin gland mai narkewa, hanta da kodan T1 / 2 - 1.5-4.5 awanni.Ya cire shi daga kodan .. Idan ya sami aiki na keɓaɓɓiyar aiki, metformin na iya tarawa.

Sayi LANGERINE

Sayi kan farashi mai sauki:

Baƙi za su yi godiya a gare ku idan kun rubuta a cikin abin da kantin magani na kan layi kuka samo mafi kyawun bayarwa.

Rating na baƙi a kan sikelin "farashin / tasiri": 37. : 2.92)
Ana lodawa ...

Idan kun yi amfani da maganin LANZHERIN (LANAGERIN), kada kuyi laushi don barin sake duba ku game da amfani da maganin. Yana da kyau a kimanta LANGERINE da akalla sigogi biyu: farashi da tasiri. Zaka taimaka wa wasu idan ka nuna cutar da ta haifar da kwayar.

Langerin - bayanin miyagun ƙwayoyi, umarnin don amfani, sake dubawa - Portal na likita

Rubuta bita
1 sake dubawa

Masu kera: Zentiva a.s (Slovak Republic)

Abubuwa masu aiki

Class of cututtuka

• Mellitus na rashin insulin-da ke fama da cutar kansa

Clinical da kungiyar magunguna

• Ba a kayyade ba. Duba umarnin

Aikin magunguna

Kungiyar magunguna

• Hypoglycemic roba da sauran jami'ai a cikin haɗuwa

Yi amfani yayin daukar ciki

A lokacin daukar ciki, yana yiwuwa idan ana tsammanin tasirin magani ya wuce yuwuwar haɗari ga tayin (ba a gudanar da nazarin ingantaccen nazari akan amfanin lokacin daukar ciki ba).

Bangaren FDA na aiki ga tayin shine B.

A lokacin jiyya kamata ya daina shayarwa.

Haɗi tare da wasu kwayoyi

Sakamakon metformin yana raunana ta hanyar thiazide da sauran diuretics, corticosteroids, phenothiazines, glucagon, hormones thyroid, estrogens, ciki har da kamar yadda wani bangare na hana hana daukar ciki, phenytoin, acid nicotinic, sympathomimetics, antagonists na alli, isoniazid.

A cikin kashi ɗaya a cikin masu sa kai masu lafiya, nifedipine ya karɓi sha, Cmax (20%), AUC (9%) metformin, Tmax da T1 / 2 basu canza ba.

Tasirin hypoglycemic yana haɓaka ta insulin, abubuwan da suka samo asali na sulfonylurea, acarbose, NSAIDs, MAO inhibitors, oxytetracycline, ACE inhibitors, abubuwan ƙira na clofibrate, cyclophosphamide, beta-blockers.

Nazarin yin hulɗa guda ɗaya a cikin masu ba da agaji na lafiya ya nuna cewa furosemide yana ƙaruwa Cmax (da kashi 22%) da AUC (da kashi 15%) na metformin (ba tare da manyan canje-canje a cikin izinin fitowar na metformin ba), metformin yana rage Cmax (da kashi 31%), AUC (da 12 %) da T1 / 2 (32%) na furosemide (ba tare da manyan canje-canje ba game da karɓar furosemide na yara). Babu bayanai game da hulɗa da metformin da furosemide tare da amfani na tsawan lokaci. Magunguna (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren da vancomycin) sun ɓoye a cikin tubules suna gasa don tsarin jigilar tubular kuma, tare da tsawan magani, na iya haɓaka Cmax na metformin da kashi 60%. Cimetidine yana rage jinkirin kawar da metformin, wanda ke kara haɗarin haɓakar lactic acidosis. Rashin jituwa tare da barasa (ƙarancin haɗarin haɓakar madara acidosis).

Kariya don amfani

Ya kamata a sa ido a kan aikin fyaɗe, yin ɗamara, da kuma glucose jini. Musamman saka idanu sosai kan matakan glucose na jini ya zama dole yayin amfani da metformin a hade tare da sulfonylureas ko insulin (haɗarin hypoglycemia).

Ya kamata a gudanar da magani tare da metformin da insulin a asibiti har sai an samar da isasshen kashi na kowane magani. A cikin marasa lafiya a kan ci gaba da jiyya tare da metformin, ya zama dole don ƙayyade abubuwan da ke cikin bitamin B12 sau ɗaya a shekara saboda yuwuwar rage ƙarfin sha.

Wajibi ne don tantance matakin lactate a cikin plasma aƙalla sau 2 a shekara, kuma tare da bayyanar myalgia. Tare da karuwa a cikin abubuwan lactate, an soke maganin.

Kada kuyi amfani dasu kafin aikin tiyata kuma a cikin kwanaki 2 bayan an yi su, haka kuma cikin kwanaki 2 kafin da bayan gwajin gwaji (iv urography, angiography, da sauransu).

Makamantan kwayoyi:

** Jagorar Magani don dalilai ne na bayanai kawai. Don ƙarin bayani, a duba batun masana'anta.

Kada ku sami magungunan kai, kafin ku fara amfani da Langerin, ya kamata ku nemi likita. EUROLAB ba shi da alhakin lahanin da ya haifar ta hanyar amfani da bayanan da aka sanya a jikin tashar.

Duk wani bayani a kan yanar gizon baya maye gurbin shawarar likita kuma ba zai iya zama tabbacin ingancin tasirin maganin ba.

Shin kuna sha'awar Langerin? Shin kuna son sanin cikakken bayani ko kuna buƙatar ganin likita? Ko kuna buƙatar dubawa? Zaku iya yi alƙawari tare da likita - asibiti YuroLab koyaushe a hidimarku! Mafi kyawun likitoci za su bincika ku, ku ba da shawara, ku bayar da taimako da suka wajaba kuma ku yi bincike. Hakanan zaka iya kira likita a gida. Asibitin YuroLab buɗe muku a agogo.

** Hankali! Bayanin da aka gabatar a cikin wannan jagorar magunguna an yi shi ne don kwararrun likitoci kuma bai kamata su zama dalilai na shan magani ba. An bayar da bayanin maganin. Marasa lafiya suna buƙatar ƙwararrun shawara!

Haihuwa da lactation

Contraindicated a cikin ciki da kuma lactation.

Yi amfani da shi don aikin hanta mai rauni

An kwantar da shi a cikin aikin hanta mai rauni.

Yi amfani da shi don aikin keɓaɓɓiyar aiki

Aka kwantar da shi a cikin raunin na koda.

Yi amfani da tsufa

Ba'a bada shawarar Metformin ga marasa lafiya sama da shekaru 60, wanda ke da alaƙa da haɓakar haɗarin lactic acidosis.

Umarni na musamman

Ba'a bada shawara ga cututtukan m, daɗaɗɗar cututtukan cututtukan fata da cututtukan kumburi, raunin da ya faru, cututtukan tiyata, da haɗarin rashin ruwa.

Kada ayi amfani dasu kafin aikin tiyata kuma cikin kwanaki 2 bayan an yi su.

Ba'a ba da shawarar yin amfani da metformin a cikin marasa lafiya fiye da shekaru 60 da waɗanda ke yin aiki na zahiri, wanda ke da alaƙa da haɓakar haɓakar lactic acidosis.

Lokacin yin jiyya, ya zama dole don saka idanu akan aikin renal, ƙuduri na abubuwan lactate a cikin plasma ya kamata a aiwatar da su aƙalla sau 2 a shekara, kuma tare da bayyanar myalgia.

Za'a iya amfani da Metformin a hade tare da sulfonylureas. A wannan yanayin, musamman saka idanu na matakan glucose na jini ya zama dole.

Yin amfani da metformin a matsayin wani ɓangare na maganin haɗin gwiwa tare da insulin ana bada shawarar a asibiti.

Hulɗa da ƙwayoyi

Tare da yin amfani da lokaci guda tare da abubuwan da aka samo na sulfonylurea, acarbose, insulin, salicylates, MAO inhibitors, oxygentetracycline, ACE inhibitors, tare da clofibrate, cyclophosphamide, tasirin hypoglycemic na metformin na iya inganta.

Tare da yin amfani da lokaci guda tare da GCS, hana rigakafin hormonal don sarrafawa na baka, adrenaline, glucagon, hormones thyroid, abubuwan da ke tattare da kwayoyin halittar thiazide, abubuwan da aka samo na nicotinic acid, raguwar tasirin hypoglycemic na metformin mai yiwuwa ne.

Amfani da cimetidine na iya ƙara haɗarin lactic acidosis.

37. : 2.92)
Ana lodawa ...

Umarnin LANGERIN (LANAGERIN)

Lambar ATX: A10BA02

Ana amfani da Metformin daga narkewa. Cmax a cikin plasma an kai shi kimanin awa 2 bayan shigowa. Bayan awanni 6, cirewar daga cikin jijiyoyin mahaifa zai kare kuma yaduwar metformin a cikin plasma sannu a hankali Hakanan bashi da alaqa da sunadaran plasma. Yana tarawa a cikin gland mai narkewa, hanta da kodan T1 / 2 - 1.5-4.5 awanni.Ya cire shi daga kodan .. Idan ya sami aiki na keɓaɓɓiyar aiki, metformin na iya tarawa.

Umarnin don amfani

Tsarin saki, abun da aka shirya da marufi

10 inji mai kwakwalwa - blisters (3) - fakitoci na kwali. - blisters (6) - fakitoci na kwali. - blister (9) - fakitoci na kwali.

Allunan da aka sanya fim, 850 MG: 30, 60 ko 90 inji mai kwakwalwa. - LSR-003625/10, 04.30.10

Ga marasa lafiya da basa karbar insulin, a cikin kwanakin farko 3 - 500 mg sau 3 a rana. ko 1 g sau 2 a rana. a lokacin abinci ko bayan abinci. Daga rana ta 4 zuwa rana ta 14 - 1 g sau 3 a rana. Bayan rana ta 15, ana daidaita sashin shan la'akari da matakin glucose a cikin jini da fitsari. Adadin kulawa shine 100-200 mg / rana.

Tare da yin amfani da insulin a lokaci guda cikin adadin ƙasa da raka'a 40 / rana. tsarin magunguna na metformin iri daya ne, yayin da za a iya rage adadin insulin a hankali (ta hanyar raka'a 4-8 / kowace rana). Idan mai haƙuri ya sami fiye da raka'a 40 / rana, to, yin amfani da metformin da raguwa a cikin adadin insulin yana buƙatar kulawa sosai kuma ana gudanar da shi a asibiti.

Haihuwa da lactation

Contraindicated a cikin ciki da kuma lactation.

Sayi LANGERINE

Sayi kan farashi mai sauki:

Baƙi za su yi godiya a gare ku idan kun rubuta a cikin abin da kantin magani na kan layi kuka samo mafi kyawun bayarwa.

Rating na baƙi a kan sikelin "farashin / tasiri": 37. : 2.92)
Ana lodawa ...

Idan kun yi amfani da maganin LANZHERIN (LANAGERIN), kada kuyi laushi don barin sake duba ku game da amfani da maganin. Yana da kyau a kimanta LANGERINE da akalla sigogi biyu: farashi da tasiri. Zaka taimaka wa wasu idan ka nuna cutar da ta haifar da kwayar.

Langerin: sake dubawa game da magani, farashi, umarnin

Langerin yana ɗayan magunguna masu yawa waɗanda ake amfani da su don magance tsarin ilimin da ake kira mellitus-non-insulin-dogara da ciwon sukari mellitus. Magungunan yana daga cikin rukunin magunguna na biguanide, babban tasiri wanda shine rage buƙatar samar da insulin.

Farashin Langerin a cikin magunguna, dangane da adadin da ake buƙata, na iya kasancewa daga ɗari ɗari zuwa ɗari uku rubles.

Langerin magani ne na baka wanda aka yi amfani dashi a cikin hadaddun maganin ciwon sukari. Babban abincinta shine metformin abu. Magungunan yana ɗayan magunguna masu rage sukari kuma ana amfani dashi sau da yawa don daidaita matakan sukari na jini a cikin masu ciwon sukari.

Ofayan ɗayan magunguna masu yiwuwar irin wannan maganin shine gudanarwarsa dangane da rashin aiki na allunan da aka yi amfani dasu a baya daga ƙungiyar sulfonylurea. Bugu da kari, kiba babbar matsala ce ta saduwa ga duk mutanen da ke dauke da ciwon sukari.

Abin da ya sa, Langerin ya ba da damar rage yawan sukari kawai, amma yana ba da gudummawa ga jinkirin daidaita ƙimar haƙuri.

Kayan magani da alamomi don amfani

Hanyar aiwatar da aikin babban maganin yana da alaƙa da iyawarta don dakatar da ayyukan gluconeogenesis, kazalika da ayyukan ƙaddamar da mayukan kitse kyauta da hadawar iskar shaƙa.

Wani wakilin aji na biguanide ba ya shafar adadin insulin da aka saki a cikin jini, amma yana canza magungunansa ta hanyar rage yawan haɗarin insulin da ƙura da kuma ƙara yawan adadin insulin zuwa proinsulin.

Batu mai mahimmanci a cikin aikin aiwatar da irin waɗannan allunan shine ƙarfafa haɓakar glucose ta ƙwayoyin tsoka.

Babban mahimmancin amfani da magani shine haɓakar kamuwa da cutar insulin-a cikin mutum, musamman tare da rashin daidaituwa ga abincin da aka bi.

Babban kaddarorin magunguna na Langerin sun haɗa da:

• yana rage adadin haemoglobinꓼ glycated
• neutralizes juriya insulin Kwayoyin zuwa hormone insulin
• yana da kyau yana tasiri daidaitaccen bayanin furotin na jini plasmas
• rage mummunan cholesterolꓼ

Bugu da ƙari, yin amfani da miyagun ƙwayoyi zai iya daidaita nauyin jikin mutum.

Umarnin don amfani da allunan

Ana amfani da maganin miyagun ƙwayoyi Langerin a cikin nau'ikan allunan da aka rufe.

Allunan an cika su a cikin jaka na filastik, wanda aka rufe tare da tsare tsare na aluminium.

An sanya fakitoci a cikin kwali mai kwali tare da umarnin don amfani da miyagun ƙwayoyi.

Dogaro da maganin da ake buƙata na maganin da aka yi amfani da shi, ana iya siyan magani tare da sashi na:

1. Miliyan 500.
2. Milligrams 850.
3. Graaya daga cikin gram na abu mai aiki.

Hanyar shan allunan magana ce ta baki, lokacin cin abinci ko bayan sa. Likitocin da ke halartar sun wajaba a bayar da magani ga kowane mai haƙuri daban-daban dangane da tsananin cutar. Hakanan, ƙwararren likita ya ƙayyade yawan adadin magunguna yayin rana.

Umarnin-Langerin don amfani yana bada shawarar fara aikin warkewa tare da mafi karancin sashi na 500 MG na kayan aiki. Yawan allurai na maganin a lokacin zai iya zama daga daya zuwa uku.

A hankali, za a iya ƙara yawan zuwa 850 MG na ƙwayar abu mai aiki a cikin yini (sau ɗaya sau biyu a rana).

Likita mai halartar yana lura da yanayin haƙuri kuma, ba fiye da sau ɗaya a mako ba, yana daidaita adadin maganin da aka karɓa a sama.

Hakanan an wajabta magungunan don magance cutar a cikin yara sama da shekaru goma. Monotherapy ya kamata ya fara da sashi na 500 MG na kayan aiki sau ɗaya ko sau biyu a rana. Bayan wani lokaci, an ba da izinin ci gaba na digiri a cikin ƙwayoyi, amma ba fiye da gram biyu a rana ba, an kasu kashi biyu zuwa uku.

Yawanci, canji a cikin yawan ƙwayoyi yana faruwa bayan kwanaki goma zuwa goma sha biyar dangane da sakamakon gwajin jini don matakin glucose.

A wasu halaye, shirye-shiryen kwamfutar hannu wani ɓangare ne na haɗin maganin tare da injections na insulin.

Ya kamata a lura cewa an gudanar da kulawa ta lokaci guda na Langerin tare da insulin, abubuwan da ake amfani da su na sulfonylurea, acarbose, ko ACE inhibitors don haɓaka tasirin hypoglycemic na magungunan.

A wasu halaye, likita mai halartar na iya maye gurbin amfani da Langerin tare da Allunan irin wannan abun da ke ciki. A yau, akwai manyan adadin magunguna, babban sinadaran aiki wanda shine metformin.

Farashin magungunan analog na iya bambanta sosai, gwargwadon kamfanin da ke kera magunguna.

Waɗanne abubuwa suke amfani da su?

Ba daidai ba da aka zaɓa sashi ko rashin jituwa tare da shawarwarin likitocin da ke halartar na iya haifar da bayyanar da martanin cutar yayin shan maganin.

Bugu da ƙari, akwai lokuta waɗanda aka haramta amfani da magani a kan metformin.

Umarnin don amfani da miyagun ƙwayoyi yana nuna jerin manyan abubuwan hana haihuwa.

Babban sabbin hanyoyin amfani da allunan ta Langerin sun hada da masu zuwa:

• matsanancin rauni na hanta ko aikin koda, karancinsu ꓼ
• giya, ciki har da na kullum formꓼ
• zuciya ko rashin numfashiꓼ
• m rashin ƙarfi infarctionꓼ
• yanayin cutar rashin lafiyan cuta ko asalinsu
• ci gaba da ciwon sukari ƙafa ciwoabet
• a gaban rashin haƙuri ga metformin da haɓakar halayen rashin lafiyan jijiyoyin
• kasancewar kamuwa da cututtukaꓼ
• azumi tare da ciwon sukari ko bin wani abincin wanda abincinsa na yau da kullun bai wuce kilocalories dubu ba
• kafin da bayan tiyataꓼ
• tare da raunin kwanan nan mai rauniꓼ
• kafin da bayan binciken da suke amfani da isotropes na aidin iodineꓼ
• ketoacidosis da lactic acidosis.

Bugu da kari, mata bai kamata su sha maganin ba yayin daukar ciki da lactation.

Aukuwa na sakamako masu illa na iya bayyana kansa a sashin wasu bangarori da tsarin jikin mutum - na ciki, jijiyoyin jini, tsarin zuciya, jijiyoyin fata. Babban mummunan halayen da zai iya faruwa sakamakon shan magungunan sune:

1. Haske mai ƙanshi. Wani lokacin tashin zuciya yana faruwa a cikin nau'in ciwon sukari na 2. Ana iya maye gurbin tashin hanci ta amai
2. Nau'in ciki mai raɗaɗi.
3. Bayyanar ɗanɗano mai ƙarfe a cikin rami na baka.
4. Hematopoiesis da hemostasis.
5. Megaloblastic anemia.
6. Rage sukari na jini a matakin da aka yarda - hypoglycemia.
7. Fitowar rauni a jiki.
8. Damuwa.
9. Hypotension.
10. Rashin lafiyar numfashi.
11. Bayyanar cututtukan fata ko fatar kan fata.

Ya kamata a kula da hankali yayin shan Langerin tare da wasu magunguna. Yin amfani da allunan a lokaci guda tare da cymeditine yana ƙara haɗarin lactic acidosis. Haɗarin Langerin tare da madaukai na madaidaici na iya haifar da sakamako iri ɗaya. A wannan yanayin, ban da yiwuwar bayyana lactic acidosis, ana iya lura da wata alama ta gazawar koda.

Yin amfani da miyagun ƙwayoyi, ya zama dole don saka idanu kan aikin al'ada na kodan da kuma ƙayyade adadin lactate a cikin plasma aƙalla sau biyu a shekara.

Bayanai game da kwayoyi da aka yi amfani da su don magance cututtukan sukari an bayar dasu a cikin bidiyon a wannan labarin.

Nuna sukari ko zaɓi jinsi don shawarwari.Bayan bincike ba a samu ba Show ShowNa bincike ba a samu ba.

Langerin - bayanin miyagun ƙwayoyi, umarnin don amfani, sake dubawa - Portal na likita

Rubuta bita
1 sake dubawa

Masu kera: Zentiva a.s (Slovak Republic)

Abubuwa masu aiki

Class of cututtuka

• Mellitus na rashin insulin-da ke fama da cutar kansa

Clinical da kungiyar magunguna

• Ba a kayyade ba. Duba umarnin

Aikin magunguna

Kungiyar magunguna

• Hypoglycemic roba da sauran jami'ai a cikin haɗuwa

Allunan bakin alkagerin (Lanagerin)

Umarnin don amfanin likita

Alamu don amfani

Nau'in ciwon sukari na 2 na cutar siga (musamman a cikin halaye tare da kiba) tare da rashin ingancin gyaran hyperglycemia tare da maganin rage cin abinci, ciki har da a hade tare da shirye-shiryen sulfonylurea.

Fom ɗin saki

500 MG filinda kwalayen tabarau, bliri fakitin fakitin 10 na kwali 6 fakiti, 500 MG mai hade da allunan, blister fakitin 10 fakitin 10 fakitin kwali 3, 500 Allunan mai rufin fim, blister fakitin fakitin 10 na kwali 9, kwayoyin hana daukar ciki, 850 MG-mai rufin fim, blister fakitin fakitin 10 na kwali 6, Allunan, 850 MG-mai rufin blister fakitin, 850 MG fil blister fakiti, 10 fakitin kwali fakitin 3, allunan da aka rufe fim 850 MG, bugu da bakin ciki 10 fakitin kwali 9, Allunan mai rufi tare da fim mai rufi 1 g, blister fakiti 10 fakitin kwali 1, Allunan mai rufi da fim harsashi 1 g, blister marufi 10 fakitin kwali 3, Allunan mai rufi da fim harsashi 1 g, blister fakiti 10 fakitin kwali 9,

Allunan mai rufi tare da fim mai rufin of 1 g, blister marufi 10 fakiti kwali 6,

Yi amfani yayin daukar ciki

A lokacin daukar ciki, yana yiwuwa idan ana tsammanin tasirin magani ya wuce yuwuwar haɗari ga tayin (ba a gudanar da nazarin ingantaccen nazari akan amfanin lokacin daukar ciki ba).

Bangaren FDA na aiki ga tayin shine B.

A lokacin jiyya kamata ya daina shayarwa.

Haɗi tare da wasu kwayoyi

Sakamakon metformin yana raunana ta hanyar thiazide da sauran diuretics, corticosteroids, phenothiazines, glucagon, hormones thyroid, estrogens, ciki har da kamar yadda wani bangare na hana hana daukar ciki, phenytoin, acid nicotinic, sympathomimetics, antagonists na alli, isoniazid.

A cikin kashi ɗaya a cikin masu sa kai masu lafiya, nifedipine ya karɓi sha, Cmax (20%), AUC (9%) metformin, Tmax da T1 / 2 basu canza ba.

Tasirin hypoglycemic yana haɓaka ta insulin, abubuwan da suka samo asali na sulfonylurea, acarbose, NSAIDs, MAO inhibitors, oxytetracycline, ACE inhibitors, abubuwan ƙira na clofibrate, cyclophosphamide, beta-blockers.

Nazarin yin hulɗa guda ɗaya a cikin masu ba da agaji na lafiya ya nuna cewa furosemide yana ƙaruwa Cmax (da kashi 22%) da AUC (da kashi 15%) na metformin (ba tare da manyan canje-canje a cikin izinin fitowar na metformin ba), metformin yana rage Cmax (da kashi 31%), AUC (da 12 %) da T1 / 2 (32%) na furosemide (ba tare da manyan canje-canje ba game da karɓar furosemide na yara). Babu bayanai game da hulɗa da metformin da furosemide tare da amfani na tsawan lokaci. Magunguna (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren da vancomycin) sun ɓoye a cikin tubules suna gasa don tsarin jigilar tubular kuma, tare da tsawan magani, na iya haɓaka Cmax na metformin da kashi 60%. Cimetidine yana rage jinkirin kawar da metformin, wanda ke kara haɗarin haɓakar lactic acidosis. Rashin jituwa tare da barasa (ƙarancin haɗarin haɓakar madara acidosis).

Kariya don amfani

Ya kamata a sa ido a kan aikin fyaɗe, yin ɗamara, da kuma glucose jini. Musamman saka idanu sosai kan matakan glucose na jini ya zama dole yayin amfani da metformin a hade tare da sulfonylureas ko insulin (haɗarin hypoglycemia).

Ya kamata a gudanar da magani tare da metformin da insulin a asibiti har sai an samar da isasshen kashi na kowane magani.A cikin marasa lafiya a kan ci gaba da jiyya tare da metformin, ya zama dole don ƙayyade abubuwan da ke cikin bitamin B12 sau ɗaya a shekara saboda yuwuwar rage ƙarfin sha.

Wajibi ne don tantance matakin lactate a cikin plasma aƙalla sau 2 a shekara, kuma tare da bayyanar myalgia. Tare da karuwa a cikin abubuwan lactate, an soke maganin.

Kada kuyi amfani dasu kafin aikin tiyata kuma a cikin kwanaki 2 bayan an yi su, haka kuma cikin kwanaki 2 kafin da bayan gwajin gwaji (iv urography, angiography, da sauransu).

Sakamakon rarrabuwar ATX:

Hanyar narkewa da narkewar abinci

Magungunan A10 don ciwon sukari

A10B Oral hypoglycemic kwayoyi

Makamantan kwayoyi:

** Jagorar Magani don dalilai ne na bayanai kawai. Don ƙarin bayani, a duba batun masana'anta.

Kada ku sami magungunan kai, kafin ku fara amfani da Langerin, ya kamata ku nemi likita. EUROLAB ba shi da alhakin lahanin da ya haifar ta hanyar amfani da bayanan da aka sanya a jikin tashar.

Duk wani bayani a kan yanar gizon baya maye gurbin shawarar likita kuma ba zai iya zama tabbacin ingancin tasirin maganin ba.

Shin kuna sha'awar Langerin? Shin kuna son sanin cikakken bayani ko kuna buƙatar ganin likita? Ko kuna buƙatar dubawa? Zaku iya yi alƙawari tare da likita - asibiti YuroLab koyaushe a hidimarku! Mafi kyawun likitoci za su bincika ku, ku ba da shawara, ku bayar da taimako da suka wajaba kuma ku yi bincike. Hakanan zaka iya kira likita a gida. Asibitin YuroLab buɗe muku a agogo.

** Hankali! Bayanin da aka gabatar a cikin wannan jagorar magunguna an yi shi ne don kwararrun likitoci kuma bai kamata su zama dalilai na shan magani ba. An bayar da bayanin maganin. Marasa lafiya suna buƙatar ƙwararrun shawara!

Abu mai aiki

- metformin hydrochloride (metformin)

Haihuwa da lactation

Ba a gudanar da cikakken ingantaccen nazarin binciken lafiyar lafiyar metformin yayin daukar ciki ba. Amfani da lokacin daukar ciki yana yiwuwa a yanayin gaggawa, lokacin da tsammanin jinya na cutar da mahaifiya ya wuce hadarin yiwuwar tayin. Metformin yana ƙetare shingen ƙarfe.

Metformin a cikin adadi kaɗan an fayyace shi a cikin madara, yayin da yawaitar metformin a cikin madara zai iya zama 1/3 na maida hankali ne a cikin plasma mahaifiyar. Ba a lura da sakamako masu illa a cikin jarirai yayin shayarwa yayin shan metformin.

Koyaya, saboda iyakance adadin bayanai, ba da shawarar amfani da lokacin shayarwa ba.

Dole ne a yanke shawarar dakatar da shayarwa ta la'akari da amfanin shayarwa da kuma haɗarin haɗarin sakamako masu illa ga jariri.

Karatuttukan da suka gabata sun nuna cewa metformin bashi da tasirin teratogenic a allurai wadanda suka ninka har sau 2-3 fiye da maganin warkewa da ake amfani da su a jikin dan adam. Metformin bashi da ƙarfin halayen ƙwayar cuta, ba ya shafar haihuwa.