Lactulose: menene, umarnin da sake dubawa

Lactulose wani laxative ne wanda yake haifar da canji a cikin kwarjinin hanji (haɓaka da yawa na lactobacilli), wanda yakan haifar da karuwa cikin acidity a cikin ƙwayar ƙwayar hanji kuma yana motsa ƙwayar jijiyoyinta. Tare da wannan, ƙarar tana ƙaruwa kuma matakalar tayi laushi.

Menene wannan Lactulose abu ne mai kamshi, farare, mai kayan fure. Zai iya narke daidai cikin ruwa. Anyi shi ne daga sukari madara kuma an sanya shi azaman oligosaccharides (wannan ƙananan sassan disaccharides ne).

Aikin magunguna - hyperosmotic, sakamako mai laxative, yana motsa motsin hanji, yana inganta shakar phosphates da Ca2 +, yana inganta haɓakar ion ammonium ion.

A ƙarƙashin tasirin miyagun ƙwayoyi, Lactobacillus acidophilus, Lactobacillus bifidus yana ƙaruwa a cikin hanji, a ƙarƙashin rinjayar wanda Lactulose ya rushe don samar da lactic acid (galibi) da kuma sashi na sashi da acetic acid. A wannan yanayin, matsin lamba na osmotic yana ƙaruwa kuma pH a cikin lumen na hanji yana raguwa, wanda ke haifar da ƙaura daga ammoniya daga jini zuwa cikin hanji, kazalika da haɓaka yawan ƙwayar jijiyoyi da haɓakar peristalsis.

Aikin yana faruwa awanni 24-48 bayan gudanarwar (sakamakon jinkirta shine saboda wucewa ta cikin jijiyar ciki).

Jiyya tare da Lactulose yana rage yawan haɗarin ion ammonium ion a cikin jini ta 25-50%, rage tsananin encephalopathy hepatic, inganta yanayin tunanin mutum kuma yana daidaita EEG. Reducesari yana rage haifuwar salmonella.

Magungunan yana kara girman feces kuma yana da sakamako mai shayewa. Magungunan ba ya shafar ƙwayar tsoka da jijiyoyin ciki.

Alamu don amfani

Me ke taimaka wa Lactulose? Dangane da umarnin, an wajabta magungunan a cikin halaye masu zuwa:

• na kullum maƙarƙashiya
• hepatic encephalopathy,
• salmonellosis (ban da na cikakkun siffofin),
• narkewa na narkewa wanda ke da alaƙa da ayyukan putrefactive sakamakon guba abinci (a cikin jarirai da yara underan shekaru 10).

Umarnin don amfani da Lactulose, sashi

An zaɓi hanyar yin magani daban daban, gwargwadon shekaru da alamomi. Ana amfani da lactulose da abinci da safe.

Tabbatattun sigogi bisa ga umarnin:

• Tare da maƙarƙashiya - 15 - 45 ml na tsawon kwanaki 3. Sannan 15 - 25 ml a rana.
• Tare da encephalopathy na hepatic - 30-50 ml, sau 3 a rana. Matsakaicin adadin yau da kullun shine 190 ml. Don rigakafin, ɗaukar 40 ml sau 3 a rana.
• A cikin cututtukan hanji mai saurin kamuwa da cuta wanda ya haifar da salmonella - 15 ml sau 3 a rana. Adadin aikin shine kwana 10 zuwa 12. Ya zama dole a sha darussan 2 - 3 tare da hutu kowace mako. A yayin karatun na uku, ɗauki 30 ml sau 3 a rana.

Don hana haɓakar ƙwayar hepatic a cikin marasa lafiya da lalacewar hanta mai yawa, an wajabta maganin 25 25 sau 3 a rana. Idan ba shi da tasiri, yana da kyau a yi amfani da haɗin lactulose da neomycin.

Tare da salmonellosis - 15 ml sau 3 a rana don kwanaki 10-12, bayan hutun kwana 7, ana maimaita magani. Idan ya cancanta, ana iya aiwatar da magani na uku a cikin sashi na 30 ml sau 3 a rana.

Ga yara, za a iya narkar da syrup da ruwa ko ruwan 'ya'yan itace.

Dos na Lactulose ga yara:

• daga shekara 7 zuwa 14 - na farko na ml 15 na syrup, sannan 10 ml a rana,
• har zuwa shekaru 6 - 5 zuwa 10 ml a rana,
• daga watanni shida zuwa shekara 1 - 5 ml a rana.

Yi amfani da hankali cikin marasa lafiya da cututtukan gastrocardial. A irin waɗannan halayen, ya kamata a fara jiyya da ƙananan allurai kuma a ƙara musu sannu a hankali don guje wa ci gaban ƙwarji.

Ba za a yi amfani dashi don zafin ciki ba, tashin zuciya, amai ba tare da tabbatar da cutar ba.

Side effects

Koyarwar tayi kashedin game da yiwuwar bunkasa wadannan sakamako masu illa yayin rubuta Lactulose:

• a wasu yanayi, tashin zuciya, amai, anorexia (rashin ci).

A kashi na farko na lactulose a allurai warkewa, zafin ciki da flatulence (tara gas a cikin hanji) na iya faruwa. Wadannan abubuwan al'aura yawanci suna bacewa 48 awanni bayan kashi na farko.

Contraindications

Lactulose yana contraindicated a cikin wadannan lokuta:

• hanci na jini
• cututtukan gado: rashi lactase, rashin haƙuri a cikin lactose, glucose-galactose malabsorption, galactosemia,
• colostomy ko Ileostomy,
• hanji na baka,
• wanda ake zargi da cutar appendicitis
• rashin hankali ga lactulose.

Ya kamata a yi amfani da hankali a cikin marasa lafiya da ciwon sukari mellitus da cututtukan gastrocardial.

Hulɗa da ƙwayoyi

Ta yin amfani da maganin rigakafi iri-iri na lokaci guda, rage tasirin warkewar maganin lactulose yana yiwuwa.

Tare da yin amfani da lactulose lokaci guda na iya rushewar abubuwa masu aiki daga shirye-shiryen mai narkewa tare da sakin-pH-dangane da sakin layi saboda gaskiyar cewa yana rage pH na abubuwan ciki.

Yawan abin sama da ya kamata

Game da yawan abin sama da ya kamata, zawo (zawo) na iya faruwa, wanda ke buƙatar cikakkiyar maganin. Cutar zawo na iya haifar da asarar ruwa mai mahimmanci, saboda haka, ana iya buƙatar gyara rashin daidaituwa na ruwa.

Analogues na Lactulose, farashin a cikin kantin magunguna

Idan ya cancanta, zaku iya maye gurbin Lactulose tare da maganin adalog a tasirin warkewa - waɗannan magunguna ne:

Lokacin zabar analogues, yana da mahimmanci a fahimci cewa umarnin don amfani da Lactulose, farashin da sake dubawa na kwayoyi tare da sakamako mai kama ba su amfani. Yana da mahimmanci don samun shawarar likita kuma kada kuyi canjin magani mai yanci.

Farashin a cikin magungunan Rashanci: Alllatin lactulose Allunan 500 MG 30 inji mai kwakwalwa. - daga 91 zuwa 119 rubles, a cikin nau'in syrup, mafi ƙarancin analog shine Lactusan syrup 300 ml - daga 300 rubles, bisa ga magunguna 591.

A nisantar da kananan yara a yanayin zafi da basa wuce + 25 ° C. Rayuwar shelf shine shekaru 2.

Pharmacodynamics

Lactulose yana halin halin rashin lafiya mai amfani da ƙwayar cuta mai lalacewa. Hakanan, wannan magani yana haɓaka haɓakar ammonium ions, tabbatacce yana shafar shaye-shayen ƙwayar salmon da foshat, yana kunna motsin hanji.

Lactulose yana rushewa a cikin hanji saboda haɗuwa da ƙwayar ciki na gida, samar da ƙananan ƙwayar nauyin kwayoyin, wanda ke haifar da karuwa a cikin ƙwayar osmotic da raguwa a cikin pH. Sakamakon wannan shine karuwa a cikin yawan abubuwan da ke cikin hanji. Wadannan tasirin suna taɓar da matakai na peristalsis a cikin hanji kuma suna shafar daidaituwa na stool. A miyagun ƙwayoyi na samar da sabuntawa na jiki jiyya na ciwon mallaka fanko.

A cikin marasa lafiya da cututtukan hepatic precoma / coma da encephalopathy na hepatic, tasirin yana faruwa ne sakamakon hana ayyukan ƙwayoyin cuta na kariya, saboda karuwar adadin ƙwayoyin cutar acidophilic (alal misali, lactobacilli), sauya ammoniya zuwa nau'in ionic saboda acidification na abubuwan da ke cikin babban hanji, da hanjin motsa jiki sakamakon da kuma rage girman pH a cikin hanji, gami da rage yawan sinadarin da ke kunshe-guba ta hanyar karfafa ayyukan microorgan zmov dauke da ammonia a sake amfani da kwayan gina jiki kira tsari.

Lactulose wani prebiotic ne wanda ke haɓaka haɓakar ƙwayoyin cuta masu amfani (lactobacillus da bifidobacteria), wanda hakan yana hana ci gaban yiwuwar ƙwayoyin cuta na ƙwayoyin cuta (Escherichia coli, Clostridium) kuma yana taimakawa haɓaka daidaituwa na ƙwayar hanji. A miyagun ƙwayoyi zai iya hana ci gaban da haifuwa da shigella da salmonella, baya rage yawan bitamin, kuma amfani da shi baya zama jaraba. Lactulose yana farawa awanni 24 da 48 bayan gudanarwar, wanda aka yi bayani ta hanyar narkar da abu ta hanyar narkewa.

Pharmacokinetics

Matsayin sha na lactulose lokacin da yake wucewa ta cikin jijiyoyi mara nauyi. Kashi 3% na kashi da aka dauka kawai ana keɓance ta ta hanjin kodan. Ba tare da shaye shaye ba, magungunan ya isa hanjin, inda ya tsage ta daga tsintsiyar hanji. Lactulose yana metabolized kusan 100% lokacin da aka ɗauka a cikin adadin kashi na 40-75 ml. Lokacin da aka kera magunguna a allurai masu girma, sinadarin da ke aiki mai kasala yana jujjuya shi da jijiyoyin da ba su canzawa.

Contraindications

• Maganin jini na jini
• Cututtukan gado: rashi lactase, rashin haƙuri a cikin lactose, glucose-galactose malabsorption, galactosemia,
• Kostodiya ko ileostomy,
• Matsewa na hanji,
• Abubuwan da ake zargi da fargaba
• Rashin hankali ga lactulose.

Dangane da umarnin, ya kamata a yi amfani da Lactulose tare da taka tsantsan a cikin marasa lafiya da ke fama da cutar sankarar bargo, cututtukan gastrocardial.

Umarnin don amfani da Lactulose: hanya da sashi

Ana ɗaukar syrup Lactulose a baki, idan ana so, ana iya diluted da ruwa ko ruwan 'ya'yan itace.

Ana amfani da maganin yau da kullun da magani yayin da likita ya dogara da alamun asibiti.

• Maƙarƙashiya: kashi na farko ga masu haƙuri - 15-45 ml na farkon kwanaki 3 na farko, tabbatarwa - 10-25 ml, kashi na farko ga yara masu shekaru 7-14 - 15 ml, tabbatarwa - 10 ml. Yankin farko da tabbatarwa na maganin Lactulose syrup ga yara masu shekaru 1-6 - 5-10 ml, daga watanni 1.5 zuwa shekara 1 - 5 ml. Ya kamata a sha miyagun ƙwayoyi sau 1 a kowace rana yayin karin kumallo,
• Encephalopathy na hepatic: 30-50 ml sau 2-3 a rana, don cimma sakamako na asibiti, haɓakar har zuwa 190 ml kowace rana yana yiwuwa. Don hana haɓakar ciwan hepatic, an wajabta masu haƙuri da lalacewar hanta 25 ml na syrup sau 3 a rana,
• Salmonellosis: 15 ml sau 3 a rana, lokacin karbar kudin shine kwanaki 10-12. Bayan hutu (kwana 7), ya kamata a maimaita hanya. Idan ya cancanta, magani na uku yana yiwuwa a kashi 30 ml sau 3 a rana.

Side effects

Yin amfani da Lactulose na iya haifar da sakamako mara amfani:

• Tsarin narkewa: mai yiwuwa - ƙwanƙwasawa (yawanci a farkon jiyya, daga baya sannu a hankali ya ɓace), jin zafi a cikin ciki, zawo, tashin hankali na daidaiton ruwa-lokacin lantarki (lokacin ɗaukar allurai), da wuya - tashin zuciya,
• Tsarin mara lafiyar: da wuya - tsananin zafin rai, ciwon kai, damuna,
• Sauran: watakila - haɓakar halayen rashin lafiyan, da wuya - rauni, myalgia, arrhythmia, gajiya.

Yawan abin sama da ya kamata

Lokacin shan Lactulose Syrup a cikin allurai sosai, zawo da amai na ciki na iya faruwa. A wannan yanayin, ana rage yawan maganin lactulose ko kuma gaba daya. Amai ko gudawa na iya haifar da asara mai yawa, saboda haka, ana iya buƙatar gyaran hargitsi a cikin daidaiton ruwa-electrolyte.

Umarni na musamman

Yayin cikin ciki da shayarwa, amfani da syrup mai yiwuwa ne ga alamun asibiti.

Ba za ku iya amfani da miyagun ƙwayoyi ba tare da kafa ingantaccen ganewar asali ba idan kuna jin tashin zuciya, zafin ciki ko amai.

Don hana haɓakar ƙwayar cuta a cikin marasa lafiya tare da cututtukan gastrocardial, sashi na farko ya kamata ya zama ƙasa da shawarar, dole ne a ƙara hankali, yana kawowa ga warkewar tasiri.

Idan zawo ya kamu, to ya kamata a dakatar da Lactulose.

Ana amfani da miyagun ƙwayoyi musamman a hankali don raunuka na cututtukan ƙwayar cuta a cikin haƙuri tare da masu ciwon sukari mellitus.

A cikin marasa lafiya da ke shan magani fiye da watanni 6, ana bada shawara don saka idanu akai-akai matakin potassium, carbon dioxide da chlorine a cikin jini na jini.

Hulɗa da ƙwayoyi

Za'a iya rage tasirin asibiti na magungunan ƙwayar cuta ta hanyar ƙwayoyin cuta-na jigilar kwayoyi. Sakamakon lactulose yana rage pH na abubuwan da ke cikin hanji, saboda haka, lokacin da aka sha shi tare da magunguna masu narkewa tare da saki mai pH, sakin abubuwan da ke aiki na iya lalacewa.

Analogues na Lactulose sune: Dufalac, Goodluck, Livolyuk-PB, Romfalak, Portalac, Normase, Forlax, Dinolak, Exportal da sauransu.

Farashin Lactulose a cikin magunguna

A yanzu, ba a san farashin Lactulose ba, tunda ba a sayar da magani a cikin sarƙoƙin magunguna ba. Kudin analog, Dufalac syrup, ya bambanta daga 270 zuwa 346 rubles a kwalbar 200 ml, daga 465 zuwa 566 rubles a kwalban 500 ml, daga 845 zuwa 1020 rubles a kowace kwalban 1000 ml.

Bayanin da abun da ke ciki

Ana samar da maganin ta hanyar bayyanar, m ruwa mai gani, wanda zai iya zama mara launi ko launin rawaya mai launin ruwan hoda.
A matsayin sashi mai aiki, ƙwayar ta ƙunshi lactulose. Baya ga shi, tsarin maganin yana hada da citric acid da ruwa don allura azaman kayan taimako.

Kungiyar magunguna

Lactulose maganin laxative ne wanda yake da tasirin sakamako. A lokacin warkarwa, motsa jiki na hanji yana motsawa, kuma yawan shan phosphates da alli yana inganta. Maganin yana kara kawar da ion ammonium ion.

A ƙarƙashin tasirin microflora na hanji, lactulose yana rushewa cikin ƙananan ƙwayoyin kwayoyin halitta mai nauyi, a sakamakon haka, pH yana raguwa kuma matsa lamba na osmotic ya tashi, wanda ke haifar da karuwa a cikin yawan feces. Duk wannan yana haifar da motsawar motsin hanji da canji a cikin daidaituwa na stool. Tare da taimakon miyagun ƙwayoyi, yana yiwuwa a maido da halayyar ɗan adam na aikin mallaka.

Tare da encephalopathy na hepatic, precoma da coma, sakamakon maganin yana da alaƙa da ƙin ƙwayoyin cuta na kariya da karuwa da yawan ƙwayoyin cutar acidophilic, alal misali, lactobacilli. Saboda gudanar da miyagun ƙwayoyi, abubuwan da ke cikin ciki sun kasance acidified, kuma ammoniya ya shiga cikin nau'in ionic, adadin sinadarin da ke dauke da guba yana raguwa, wannan ya faru ne ta hanyar ƙwayoyin ƙwayoyin cuta waɗanda ke amfani da ammoniya don ƙwayar ƙwayar ƙwayar cuta.

Lactulose shine ƙwayar cuta prebiotic. Yana haɓaka haɓakar ƙwayoyin ƙwayoyin cuta, irin su bifidobacteria da lactobacilli, kuma su, bi da bi, suna hana haɓakar ƙwayoyin cutar kwayar cutar: E. coli da clostridia.

Magungunan yana hana girma da haifuwar shigella da salmonella, ba ya tsoma baki tare da shan ƙwayoyin bitamin, kuma ba mai jaraba bane.

Ana lura da tasirin warkewar magunguna a cikin 24-48 bayan aikinta (jinkirta laxative sakamako daga miyagun ƙwayoyi yana haɗuwa da sashi ta cikin narkewa).

Kasancewar maganin yana da ƙasa, har zuwa 3% na kashi da aka ɗauka yana cire kodan. Bangaren da ke aiki ya kai ga masara, inda microflora ya raba. Magungunan, wanda aka ɗauka a kashi 40-75 ml, yana ƙarfe ne gabaɗaya, a mafi yawan allurai, an rage ƙwayar maganin a cikin bile ba canzawa.

Na manya

• tare da maƙarƙashiya, don tsara abin da ake amfani da shi na jijiyoyin cikin ɓacin rai,
• don taushi matattara don dalilai na likita tare da basur, a cikin bayan aikin tiyata na tiyata a kan babban hanji ko a dubura,
• tare da encephalopathy na hepatic don magancewa da hana ciwan hepatic da precoma.

Dangane da alamu, ana iya amfani da maganin a cikin yara daga farkon kwanakin rayuwa. Ya kamata a gudanar da magani a cikin marasa lafiya 'yan ƙasa da shekara 18 kawai a ƙarƙashin kulawar likita kuma a lokuta na musamman.

Ga masu juna biyu da masu shayarwa

Yayin gestation da lactation, ana iya amfani da syrop Lemoulose bisa ga alamu.

Contraindications

An sanya maganin a cikin ƙwayar cuta idan mai haƙuri ya bayyana wani ɗayan cututtukan masu zuwa:

• mutum haƙuri zuwa ga abun da ke ciki na miyagun ƙwayoyi:
• galactosemia,
• hanji na baka,
• hanci na jini
• rashin jituwa ga galactose, sukari na 'ya'yan itace, rashin lactase, malalakin tsarin disaccharides,
• colostomy da ileostomy.

Lactulose an contraindicated a cikin lokuta na zargin appendicitis, kuma ya kamata a wajabta shi da taka tsantsan ga marasa lafiya da ciwon sukari mellitus.

Sashi da Gudanarwa

Na manya

Ana amfani da lactulose a baki, tare da ko bayan abinci.

Ana iya ɗaukar takaddar yau da kullun sau 1 ko zuwa kashi biyu.

An zaɓi tsarin magani a kowane yanayi daban-daban. Lokacin da ake rubuta guda ɗaya a rana, dole ne a sha maganin a lokaci guda, alal misali, a karin kumallo.

Don kawar da maƙarƙashiya, miyagun ƙwayoyi a cikin kwanakin farko na 3 ya kamata a ɗauki 15-255 a rana, to, ana rage sashi na yau da kullun zuwa 10-30 ml.

Bayan shan magungunan, ana lura da motsi a cikin kwanakin 2 na farko. Hanyar warkewa na iya wucewa daga makonni 4 zuwa watanni 3-4.

Ga marasa lafiya da ke fama da ƙwayar hepatic, precoma, encephalopathy, an wajabta magunguna 30-45 ml a rana. Abu na gaba, an zaɓi sashi don haka motsin hanji ya kasance sau 2-3 a rana. Tsawan lokacin jiyya na iya zama watanni 3 ko fiye.

Bayan maganin tiyata, ana sanya magani a 10-30 ml sau 3 a rana. Wajibi ne a sha maganin bayan awa 18-24 bayan aikin don kwanaki 3-5.

Ga yara, an zaɓi sashi na miyagun ƙwayoyi daban-daban dangane da alamu da shekarun yaran.

Don kawar da maƙarƙashiya ga yara na farkon shekara ta rayuwa, an wajabta maganin a cikin maganin yau da kullun na 5 ml, ga marasa lafiya masu shekaru 1-6 a rana, ana iya ba su daga 5 zuwa 10 ml a rana, ga marasa lafiya masu shekaru 7-14 shekaru - 15 ml a kowace rana.

Ga yara kanana sama da shekaru 14, ana wajabta maganin a allurai ga manya.

Bayan tiyata, yara 'yan ƙasa da shekara ɗaya ana sa musu magani guda na 5 ml, sama da shekara 5-10 ml. Administrationarfin mulki da yawa sau 2-3 a rana. Wajibi ne a sha maganin bayan sa'o'i 18 zuwa 24 na kwanaki 3-5.

Ga masu juna biyu da masu shayarwa

Yayin daukar nauyin tayin da shayarwa, ana amfani da sikirin na Lactulose kamar yadda ya saba.

Yin hulɗa tare da wasu kwayoyi

Lokacin amfani da Lactulose syrup a cikin maganin warkewa a hade tare da wasu magunguna, ba a lura da hulɗa na miyagun ƙwayoyi ba, amma, duk da wannan, ba sa buƙatar shaye su a lokaci guda (ƙaramar tazara tsakanin allurai ya zama 2 hours).

Antibacterial da antacid jamiái suna rage sakamakon laxative. Lactulose yana canza pH-dogara sakin magunguna masu narkewa.

Yanayin ajiya

Ya kamata a adana miyagun ƙwayoyi a cikin duhu, wuri mara amfani a zazzabi na 5-25. Rayuwar shiryayye na Lactulose syrup shine shekaru 3, bayan wannan bazai iya sha ba, dole ne a zubar dashi.

Kuna iya siyar da magani ba tare da takardar likita ba, amma shan shi ba tare da fara tuntuɓar likita ba da shawarar.

Baya ga Lactulose syrup, da yawa analogues ana kan sayarwa:

1. Normase cikakke ne analog na maganin Lactulose syrup. Ana siyar da maganin rage ƙoshin maye a cikin syrup, wanda za'a iya tsara shi ga marasa lafiya na kowane tsararraki, gami da lokacin ciki da lactation.
2. Dufalac ya ƙunshi lactulose azaman abu mai aiki. Ana samar da magani a cikin syrup, wanda za'a iya amfani dashi a cikin yara na farkon shekara ta rayuwa, mata a cikin matsayi da shayarwa.
3. Dinolak a matsayin abu mai aiki, ƙwayar ta ƙunshi lactulose da simethicone. Ana sayar da maganin a cikin emulsion don maganin baka, ana iya tsara shi ga yara na kowane zamani, masu juna biyu da masu shayarwa.
4. Transulose shine maganin laxative na Faransa wanda aka yi shi da nau'in gel. An bayyana tasirin warkewar magani ta hanyar paraffin da lactulose. Ana iya yin maganin taƙasa kawai ga manya. Transulose yana contraindicated a cikin mata a cikin matsayi da tallafawa shayarwa.
5. Senadexen shine phytopreching, wanda yake maye gurbin Lactulose syrup a cikin rukunin warkewa. Ana samar da magani a allunan da aka yarda wa yara daga shekara guda da masu haƙuri. Abubuwan da ke aiki da miyagun ƙwayoyi suna keɓance a cikin madarar nono kuma suna iya haifar da baƙin ciki a cikin jariri, don haka yayin aikin jiyya, ya kamata a canja ɗan jaririn zuwa cakuda.

Don ɗauka analog maimakon Lactulose syrup, yana halatta kawai bayan tuntuɓar ƙwararrun masani.

Kudin Lactulose shine kimanin 435 rubles. Farashin ya fara daga 111 zuwa 967 rubles.