Galvus analogues
Galvus (Allunan) Rating: 208
Galvus shiri ne na kwamfutar hannu don maganin nau'in mellitus na ciwon sukari na 2 dangane da vildagliptin a cikin sashi na 50 MG. Ana iya tsara shi duka biyu azaman maganin tauhidi kuma a matsayin ɓangaren haɗin magani idan akwai rashin ingancin abinci da motsa jiki.
Analogs na miyagun ƙwayoyi Galvus
Analog ya fi tsada daga 981 rubles.
Onglisa magani ne na Amurka don magance nau'in ciwon sukari na 2 na sukari dangane da saxagliptin a cikin sashi na 2.5 ko 5 mg. An wajabta shi ban da aikin jiki da rage cin abinci don inganta sarrafa glycemic.
Analog ya fi tsada daga 857 rubles.
Mai masana'anta: Beringer Ingelheim (Austria)
Siffofin Saki:
- Allunan 5 MG, pc 30., Farashin daga 1648 rubles
Umarnin don amfani
Trazhenta - wani magungunan Ostaraliya da aka yi niyya don magance cututtukan ciwon sukari na 2, ana iya sa shi duka biyu a matsayin maganin- kuma a matsayin ɓangaren haɗin maganin. Abinda ke aiki kawai a cikin abun da ke ciki shine linagliptin a cikin sashi na 5 MG. Ba a wajabta Trazenta don kamuwa da cututtukan type 1 ba, a lokacin daukar ciki, lactation, da kuma a cikin yara 'yan ƙasa da shekaru 18.
Analog ya fi tsada daga 1418 rubles.
Mai masana'anta: Merck Sharp and Dome (Amurka)
Siffofin Saki:
- Allunan 100 MG, guda biyu., Farashin daga 2209 rubles
Umarnin don amfani
Januvia magani ne na Americanan asalin Amurka don ciwon sukari. Sinadaran aiki: sitagliptin (a cikin nau'in phosphate monohydrate) 100 MG. Ana iya amfani dashi azaman ƙari ga aikin jiki da abinci don sarrafa sukari na jini.
Analog ya fi tsada daga 182 rubles.
Mai masana'anta: Ana yin karin bayani
Siffofin Saki:
- Tab. 12.5 mg, 28 inji mai kwakwalwa,, Farashin daga 973 rubles
- Tab. 25 mg, 28 inji mai kwakwalwa., Farashin daga 1282 rubles
Umarnin don amfani
Vipidia shine wakili na hypoglycemic a cikin allunan tare da alogliptin. Yana ba da raguwa a cikin glycosylated haemoglobin da glucose. An nuna shi idan akwai nau'in ciwon sukari na 2 na mellitus a cikin hanyar monotherapy, kazalika a haɗuwa da jiyya tare da sauran wakilai na hypoglycemic. Mafi kyawun sashi shine 25 mg / rana, ana ɗauka komai abinci. Contraindicated a cikin ciwon sukari ketoacidosis, type 1 ciwon sukari mellitus, mai tsanani mai rauni zuciya, na koda da gazawar hanta. Abubuwan da ke tattare da cutarwa na iya haɗawa da ciwon kai, tashin hankali a cikin hanji, fitsari, cututtukan cututtuka na gabobin ENT. Ba a ba da umarnin ƙananan yara 'yan ƙasa da shekara 18 da mata masu juna biyu saboda rashin bayanai game da aikace-aikacen.
Analogs ta hanyar nuni da hanyar amfani
| Take | Farashi a Rasha | Farashi a Ukraine |
|---|---|---|
| Janavia sitagliptin | 1369 rub | 277 UAH |
| Onglisa saxagliptin | 1472 rub | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Harshen trazhenta linagliptin | 89 rub | 1434 UAH |
Abun daban-daban, na iya daidaituwa cikin nuni da hanyar aikace-aikace
| Take | Farashi a Rasha | Farashi a Ukraine |
|---|---|---|
| Rosiglitazone mai mahimmanci, metformin hydrochloride | -- | -- |
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 rub | 15 UAH |
| Glucophage xr metformin | -- | 50 UAH |
| Reduxin Metformin, Sibutramine | 20 rub | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 rub | 12 UAH |
| Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Tsarin metformin hydrochloride | -- | -- |
| Emformorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Formethine | 37 rub | -- |
| Metformin Canon metformin, ovidone K 90, sitaci masara, crospovidone, magnesium stearate, talc | 26 rub | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 rub | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Farmland Metformin | -- | -- |
| Glibenclamide Glibenclamide | 30 rub | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Kiwon lafiya Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 rub | 170 UAH |
| Mai ciwon sukari MR | -- | 92 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Health Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Diagnizide Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 rub | -- |
| Amaril | 27 rub | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Gli karinda | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Alfika | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Gwarwar Clay | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Glimed | -- | -- |
| Glimepiride dabarini | 27 rub | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon dabarini | 50 rub | -- |
| Glimepiride Magungunan glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride lu'u-lu'u | 2 rub | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 rub | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 rub | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 rub | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Haɗu da metformin XR, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 rub | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Gzutazone dabari | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Lixumia lixisenatide | -- | 2498 UAH |
| Guarem guar gum | 9950 rub | 24 UAH |
| Insvada ta sake | -- | -- |
| Samurai | 30 rub | 90 UAH |
| Sassan Ranka | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Long Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 rub | 3200 UAH |
| Invocana canagliflozin | 13 rub | 3200 UAH |
| Jardins Empagliflozin | 222 rub | 566 UAH |
| Dulglutide Trulicity | 115 rub | -- |
Yaya za a sami analog mai rahusa na magani mai tsada?
Don neman analog mai rahusawa ga magani, jana'iza ko alaƙa, da farko muna bada shawara a kula da abun da ke ciki, wato ga abubuwa masu aiki iri ɗaya da alamomi don amfani. Abubuwa masu aiki iri ɗaya na ƙwayoyi zasu nuna cewa maganin yana da alaƙa tare da miyagun ƙwayoyi, daidai da magunguna ko madadin magunguna. Koyaya, kar ka manta game da abubuwanda suka lalace na irin kwayoyi, wanda zai iya shafar aminci da tasiri. Kada ku manta game da umarnin likitoci, magani na kai na iya cutar da lafiyar ku, don haka koyaushe tuntuɓi likitanku kafin amfani da kowane magani.
Umarni Galvus
Abun ciki
Shafin 1. ya ƙunshi 50m mg,
tsoffin abubuwan: MCC, lactose anhydrous, sitaci carboxymethyl sitaci, magnesium stearate,
Kamawa
a cikin kunshin 14, 28, 56, 84, 112 da 168 inji mai kwakwalwa.
Aikin magunguna
GALVUS - vildagliptin - wakilin aji na masu karfafa motsa jiki daga cikin kashin baya, wanda aka zaba yana hana enzyidase-4 enzyme dipeptidyl-D (DPP-4). Saurin hanzarta cikakkiyar hana aiki na DPP-4 (> 90%) yana haifar da haɓakar ɓoyayyiyar kwalliya da abinci na motsa jiki na nau'in 1 glucagon-kamar peptide (GLP-1) da glucose-polyulinptide-insulinotropic polypeptide (HIP) daga hanji zuwa cikin keɓaɓɓiyar keɓaɓɓu cikin yini.
Theara matakan GLP-1 da HIP, vildagliptin suna haifar da haɓakar haɓakar ƙwayar ƙwayar ƙwayar cuta? Kwayoyin zuwa glucose, wanda ke haifar da haɓaka ƙwayar insulin-dogara da insulin glucose. Lokacin amfani da vildagliptin a kashi 50-100 mg / a cikin marasa lafiya da ke fama da nau'in ciwon sukari na 2, an lura da haɓaka aikin aikin ƙwayoyin cuta? Matsayin ci gaba na? -Cell aiki ya dogara da matakin lalacewarsu ta farko, don haka a cikin mutane da ba su fama da ciwon sukari mellitus (tare da glucose na jini na yau da kullun), vildagliptin baya motsa ƙwayar insulin kuma baya rage glucose.
Ta hanyar ƙara yawan matakan GLP-1 na endogenous GLP-1, vildagliptin yana ƙara ƙwarewar ƙwayoyin β-sel zuwa glucose, wanda ke haifar da haɓakawa ga tsarin glucose na glucose. Decreasearin rage yawan glucagon ƙwayar abinci yayin abinci, bi da bi, yana haifar da raguwar juriya insulin.
Haɓakawa cikin insulin / glucagon rabo a kan asalin hyperglycemia, saboda karuwa a cikin matakan GLP-1 da HIP, yana haifar da raguwar haɓakar haɓakar glucose ta hanta duka a cikin lokacin prandial da bayan abinci, wanda ke haifar da raguwa a cikin matakan glucose jini.
Bugu da kari, a kan banbancin amfani da vildagliptin, an lura da raguwar matakin lipids a cikin jini na jini, duk da haka, wannan tasirin ba shi da alaƙa da tasirin sa akan GLP-1 ko HIP da haɓakawa a cikin aikin ƙwayar cuta?
An san cewa karuwa a GLP-1 na iya rage jinkirin motsa jiki, amma ba a lura da wannan tasirin ba tare da amfani da vildagliptin.
Lokacin amfani da vildagliptin a cikin marasa lafiya na 5795 tare da nau'in mellitus na sukari na 2 na 12 zuwa 52 makonni a matsayin monotherapy ko a hade tare da metformin, abubuwan da ake buƙata na sulfonylurea, thiazolidinedione, ko insulin, raguwa mai mahimmanci na dogon lokaci a cikin haɗuwa da glycated haemoglobin (HbA1c) da azumin glucose jini.
Galvus, alamomi don amfani
Type 2 ciwon sukari mellitus:
- as monotherapy a hade tare da tsarin abinci da motsa jiki,
- kamar yadda wani bangare na maganin hadewar abubuwa biyu tare da metformin, abubuwan da suka samo asali na sulfonylurea, thiazolidinedione ko insulin a yanayin rashin ingancin maganin abinci, motsa jiki da monotherapy tare da wadannan kwayoyi.
Contraindications
Hypersensitivity to vildagliptin da duk wasu abubuwan haɗin Galvus,
yara 'yan ƙasa da shekara 18 (ba a kafa ingantaccen aiki da lafiya ba).
Tare da kulawa:
mummunar ƙetarewar hanta, gami da marasa lafiya da haɓaka aiki na enzymes hanta (ALT ko AST> lokutan 2.5 sama da iyakar babba na al'ada - 2.5 × VGN),
matsakaici ko matsanancin rauni na koda (gami da ƙarshen matakin CRF akan hemodialysis) - ƙwarewa tare da amfani yana da iyaka, ba a bada shawarar magunguna don wannan rukuni na marasa lafiya ba,
toshewar cututtukan gado - rashin haƙuri tsakanin galactose, rashi lactase ko malabsorption na glucose-galactose.
Sashi da gudanarwa
Ana ɗaukar Galvus ta baka, ba tare da la'akari da cin abinci ba.
Ya kamata a zaɓi jigilar magunguna daban-daban dangane da tasiri da haƙuri.
Thewarin da aka ba da shawarar maganin a lokacin monotherapy ko kuma a matsayin ɓangaren maganin haɗin haɗakar abubuwa biyu tare da metformin, thiazolidinedione ko insulin shine 50 ko 100 mg sau ɗaya a rana. A cikin marasa lafiya da ke fama da ciwon sukari mai nau'in 2 da ke karɓar maganin insulin, ana ba da shawarar Galvus a cikin adadin 100 mg / rana.
Ya kamata a ba da magani na 50 mg / rana a cikin kashi 1 na safe, kashi na 100 MG / rana - 50 MG sau 2 a rana da safe da maraice.
Haihuwa da lactation
A cikin nazarin gwaji, lokacin da aka ayyana a allurai sau 200 sama da wanda aka ba da shawarar, magungunan basu haifar da rashin haihuwa da farkon haɓaka tayin kuma basuyi tasirin teratogenic ba akan tayi. Babu cikakkun bayanai game da amfani da miyagun ƙwayoyi Galvus a cikin mata masu juna biyu, sabili da haka bai kamata a yi amfani da maganin ba lokacin daukar ciki. A yanayin rashin wadatar abinci na glucose a cikin mata masu juna biyu, akwai karuwar hadarin haɓakar asaran haihuwa, da kuma yawan cututtukan ƙananan yara da mace-mace.
Tunda ba a san ko vildagliptin tare da madarar nono ya kebe cikin mutane ba, bai kamata a yi amfani da Galvus ba a lokacin shayarwa.
Side effects
Lokacin amfani da Galvus azaman maganin monotherapy ko a hade tare da wasu kwayoyi, yawancin raunin da ya faru sun kasance mai sauƙi, ɗan lokaci, kuma baya buƙatar dakatar da ilimin. Ba a sami daidaituwa ba tsakanin yawan bala'in haɗari (AE) da shekaru, jinsi, ƙabila, tsawon lokacin amfani, ko yin amfani da allura. Abunda ya faru na angioneurotic edema yayin jiyya tare da Galvus shine /1 / 10,000. Baya ga yanayin aikin jiyya tare da Galvus, raunin hepatic (ciki har da cutar hepatitis) da kwararar asymptomatic. A mafi yawancin halayen, waɗannan cin zarafi da karkacewa na aikin hanta suna daga ka'idojin da aka warware su daban-daban ba tare da rikitarwa ba bayan dakatar da ilimin magani. Lokacin amfani da miyagun ƙwayoyi Galvus a cikin kashi 50 mg 1 ko sau 2 a rana, yawan karuwar ayyukan enzymes hanta (ALT ko AST ≥3 × VGN) ya kasance 0.2 ko 0.3%, bi da bi (idan aka kwatanta da 0.2% a cikin rukuni na sarrafawa) . Ara yawan ayyukan enzymes na hanta a mafi yawan lokuta asymptomatic, bai ci gaba ba, kuma ba a haɗa shi da canje-canje ko cholestatic ko jaundice ba.
Umarni na musamman
A cikin lokuta mafi wuya, lokacin da ake amfani da vildagliptin, an lura da karuwa a cikin ayyukan aminotransferases (yawanci ba tare da alamun bayyanar asibiti ba). Kafin rubuta magunguna da kuma lokacin farkon shekarar magani (1 lokaci a cikin watanni 3), ana ba da shawarar don sanin sigogin ƙirar ƙwayar halittar hanta. Tare da haɓaka a cikin ayyukan aminotransferases, yakamata a tabbatar da sakamakon ta hanyar maimaita bincike, sannan kuma a kai a kai ƙayyade sigogin ƙwayoyin halittar hanta har sai sun daidaita. Idan aikin wuce haddi na AST ko ALT ya ninka har sau 3 sama da babba na ƙa'idar aiki ta hanyar bincike na biyu, an bada shawarar soke maganin. Tare da haɓakar jaundice ko wasu alamun aikin hanta mai rauni, ya kamata a dakatar da miyagun ƙwayoyi nan da nan kuma kada a sake farawa bayan daidaitattun alamun ayyukan hanta. Idan maganin insulin ya zama dole, ana amfani da vildagliptin kawai a hade tare da insulin. Bai kamata a yi amfani da miyagun ƙwayoyi don nau'in ciwon sukari na 1 ba ko don maganin ketoacidosis na ciwon sukari. A lokacin jiyya (tare da haɓakar rashin ƙarfi), ya zama dole a guji tuki motoci da shiga cikin abubuwan haɗari masu haɗari waɗanda ke buƙatar haɓakar jawo hankali da saurin halayen psychomotor.
Hulɗa da ƙwayoyi
Galvus yana da ƙarancin damar hulɗa da miyagun ƙwayoyi. Tunda Galvus ba ya canzawa enzymes na cytochrome P450, kuma baya hanawa ko haifar da wannan enzymes, hulɗar Galvus tare da kwayoyi waɗanda ke canzawa, hanawa, ko kuma haifar da P450 ba zato ba tsammani. Tare da yin amfani da vildagliptin na lokaci guda kuma baya tasiri akan ƙimar magungunan ƙwayoyi waɗanda ke maye gurbin enzymes: CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1 da CYP3A4 / 5.
Yawan abin sama da ya kamata
Kwayar cutar lokacin amfani da miyagun ƙwayoyi a kashi na 400 mg /, ana iya lura da ciwon tsoka, da wuya, huhun ciki da tashin hankali, zazzabi, edema da haɓaka mai jinkiri a cikin ƙwayar lipase (2 sau sama da VGN). Tare da karuwa a cikin kashi na Galvus zuwa 600 mg /, haɓakar edema na ƙarshen tare da paresthesias da haɓakar taro na CPK, ALT, C-reactive protein da myoglobin mai yiwuwa ne.Duk alamun bayyanar cutar shaye-shaye da canje-canje a cikin ma'aunin dakin gwaje-gwaje sun ɓace bayan dakatar da miyagun ƙwayoyi.
Jiyya: kawar da miyagun ƙwayoyi daga jiki ta hanyar dialysis ne wanda ake iya shakkar aukuwarsa. Ko yaya, babban hydrolytic metabolite na vildagliptin (LAY151) za'a iya cire shi daga jiki ta hanyar hemodialysis.
Yanayin ajiya
A cikin duhu a zazzabi da bai wuce 25 ° C ba.
Abinda aka fi so shine Galvus a cikin allunan
Vipidia (Allunan) Rating: 88 Top
Analog ya fi tsada daga 182 rubles.
Vipidia shine wakili na hypoglycemic a cikin allunan tare da alogliptin. Yana ba da raguwa a cikin glycosylated haemoglobin da glucose. An nuna shi idan akwai nau'in ciwon sukari na 2 na mellitus a cikin hanyar monotherapy, kazalika a haɗuwa da jiyya tare da sauran wakilai na hypoglycemic. Mafi kyawun sashi shine 25 mg / rana, ana ɗauka komai abinci. Contraindicated a cikin ciwon sukari ketoacidosis, type 1 ciwon sukari mellitus, mai tsanani mai rauni zuciya, na koda da gazawar hanta. Abubuwan da ke tattare da cutarwa na iya haɗawa da ciwon kai, tashin hankali a cikin hanji, fitsari, cututtukan cututtuka na gabobin ENT. Ba a ba da umarnin ƙananan yara 'yan ƙasa da shekara 18 da mata masu juna biyu saboda rashin bayanai game da aikace-aikacen.
Analog ya fi tsada daga 857 rubles.
Trazhenta - kwayoyin kan rage girman glucose na jini. Ya dogara ne akan kwayar linagliptin. Yana rage samarda glucose a cikin hanta, yana daidaita matakin glucose a cikin jini. Ciwon sukari na 2 wanda alama ce don amfani dashi a tsarin monotherapy da hada magani. Zaɓin sashi ɗaya ne. Bai zartar da ciwon sukari na 1 ba, sha'awar mutum, ketoacidosis mai ciwon sukari. Daga cikin tasirin da ba'a so ba na iya zama tari, huhun ciki, hanci. Ba a zartar da shi ba a cikin yara ƙanana 18 da kuma cikin mata masu juna biyu.
Analog ya fi tsada daga 981 rubles.
Onglisa - magani ne don lura da ciwon sukari. Aiki mai aiki na allunan sune saxagliptin. Yana rage glucagon, glucose jini kafin da bayan abinci. An wajabta shi don nau'in ciwon sukari na 2 a matsayin ƙari ga abincin a cikin hanyar monotherapy kuma a hade. Rationarƙwalwa na aiki ya dogara da nuni. Nau'in sukari na 1 na sukari, gudanarwa tare da insulin, ketoacidosis sune contraindications. Juji, ciwon kai, matsewar hanci, ciwon makogwaro yana yiwuwa tare da maganin Onglisa. Babu wani gogewa a cikin ilimin yara da mata masu juna biyu, saboda haka, ba a amfani da wannan rukunin.
Analog ya fi tsada daga 1418 rubles.
Januvia wani magani ne na hypoglycemic wanda ke ɗauke da sitagliptin. Kudinsa sun fi Galvus muhimmanci tare da adadin allunan a cikin kunshin. Yana hana samar da glucagon, yana rage glycemia. Ana amfani dashi don nau'in ciwon sukari na 2 kawai. Ana daidaita sashi gwargwadon matakan glucose na jini. Ba a amfani dashi don nau'in 1 na ciwon sukari, yawan tashin hankali. Zazzabin ciwon kai, zawo, amai, ciwon gwiwa, ciwon hanji na sama ana samun su yayin jiyya. Kamar magungunan da ke sama, ba a ba da umarnin ga yara 'yan ƙasa da shekara 18 da mata masu juna biyu.
Karin Galvus
Metformin magani ne na yau da kullun don ciwon sukari na 2, an wajabta shi ga kusan duk marasa lafiya. Na dogon lokaci na amfani, ba wai kawai an tabbatar da ingancin wannan magani ba, amma har ma an sami sakamako masu amfani da yawa ga zuciya, tasoshin jini, bakan jini. Dangane da shawarar kungiyoyin kwantar da hankali, wasu magunguna ana wajabta su ne kawai lokacin da metformin bai isa ba don rama ciwon sukari.
Allunan Galvus Met suna haɗuwa, suna ɗauke da metformin da vildagliptin. Yin amfani da miyagun ƙwayoyi na iya rage yawan allunan, wanda ke nufin hakan yana rage haɗarin rasa ɗayansu. Rashin kyau na miyagun ƙwayoyi shine mafi girman farashin magani idan aka kwatanta da wani kashi na Galvus da metformin.
| Dosages Galvus Met, mg | Matsakaicin matsakaici don shafuka 30, rubles. | Farashin allunan 30 na Galvus da Glucofage na kashi ɗaya, rubles. | Farashin farashi,% |
| 50+500 | 1550 | 875 | 44 |
| 50+850 | 890 | 43 | |
| 50+1000 | 950 | 39 |
Analogs da wasu abubuwa
Tun da Galvus sabon magani ne, kariyar patent har yanzu tana kan shi. Sauran masana'antun ba za su iya samar da Allunan tare da abu guda mai aiki ba, analogues na gida mara tsada babu su.
DPP-4 inhibitors da incetin mimetics na iya yin aiki azaman maye gurbin Galvus:
- sitagliptin (Januvius, Xelevia, Yasitara),
- saxagliptin (Onglisa),
- exenatide (Baeta),
- liraglutide (Viktoza, Saksenda).
Duk waɗannan takwarorinsu masu tsada ne, musamman Baeta, Viktoza da Saksenda. Magungunan Rasha kawai na sama shine Yasitar daga Pharmasintez-Tyumen. An yi rajistar maganin a ƙarshen 2017, har yanzu ba a same shi a cikin magunguna ba.
Idan mai haƙuri ya bi abincin, yana ɗaukar Galvus Met a mafi girman sashi, kuma sukari har yanzu yana sama da al'ada, to, kumburin ƙwayar cuta yana kusa da gajiya. A wannan halin, zakuyi ƙoƙarin kuɓutar da kwayar insulin tare da abubuwan ƙira na sulfonylurea, amma mafi kusantar su, suma zasu zama basu da tasiri sosai. Idan insulin dinka ya daina fitowa, mai ciwon sukari yana buƙatar sakewa da insulin. Kada ku jinkirta farkonsa. Rikici na ciwon sukari yana haɓaka ko da tare da ƙara yawan glucose.
Galvus ko Metformin
A cikin Galvus Mete, abubuwa masu aiki daidai suke. Su duka suna shafar matakan sukari, amma suna aiwatar da ayyukansu daga kusurwoyi mabambanta. Metformin - galibi saboda raguwa a cikin juriya na insulin, vildagliptin - karuwa a cikin aikin insulin. A zahiri, tasiri mai yawa akan matsalar shine mafi inganci. Dangane da sakamakon aunawa, ƙari na Galvus zuwa metformin yana rage haɓakar glycated da 0.6% a cikin watanni 3.
Ba ma'anar hankali ba don yanke hukunci ko Galvus ko metformin ya fi kyau. Ana ɗaukar Metformin a farkon cutar tare da abinci da wasanni, na kwayoyi, Glucofage na asali ko kayan haɓaka na Siofor sun fi kyau. Lokacin da bai wadatar ba, an kara Galvus zuwa tsarin kulawa ko an maye gurbin metformin Galvus Metom.
Mai araha mai araha ne ga Galvus
Kwayoyin sunada tsada fiye da Galvus, amma iri ɗaya mai inganci da tasiri ba su wanzu ba tukuna. Kuna iya rage jinkirin ci gaban ciwon sukari tare da horarwa na yau da kullun, rage cin abinci maras nauyi, da metformin mai arha. Mafi kyawun diyya don ciwon sukari, tsawon sauran kwayoyi ba za a buƙata ba.
Sanannun shirye-shiryen sulfonyl urea, kamar Galvus, haɓaka aikin insulin. Waɗannan sun haɗa da ƙarfi, amma ba aminci Maninil, mafi zamani Amaryl da Diabeton MV. Ba za a iya ɗaukarsu analogues na Galvus ba, tunda tsarin aikin magungunan ya sha bamban. Abubuwan da aka samo na sulfonylureas suna tsokani hypoglycemia, zubar da fitsari, hanzarta lalata ƙwayoyin beta, don haka lokacin da kuka karɓi su, ya kamata ku kasance cikin shiri don gaskiyar cewa a cikin 'yan shekaru za ku buƙaci maganin insulin. Galvus yana hana mutuwar kwayoyin sel, yana tsawaita aikin farji.
Dokokin shigar da kara
Kwarin da aka ba da shawarar Vildagliptin:
Likita na Kimiyyar Kimiyya, Shugaban Cibiyar Nazarin Diabetology - Tatyana Yakovleva
Na yi shekaru da yawa ina nazarin ciwon sukari. Yana da ban tsoro yayin da mutane da yawa suka mutu, har ma da yawa suna zama masu rauni saboda cutar sankara.
Ina cikin sauri don in faɗi albishir - Cibiyar Bincike ta Endocrinological na Kwalejin Kimiyya ta Rasha ta sami nasarar samar da magani wanda ke warkar da ciwon sukari gaba daya. A yanzu, ingancin wannan magani yana gab da kashi 98%.
Wani albishir: Ma'aikatar Lafiya ta tabbatar da ɗaukar wani shiri na musamman wanda zai biya diyyar magunguna mai yawa. A cikin Rasha, masu ciwon sukari na iya samun shi kafin 17 ga watan Fabrairu - Don kawai 147 rubles!
>> KA OREARA GAME DA GAME DA CIKIN DUNIYA
- MG 50 a farkon gudanarwa, lokacin amfani dasu tare da shirye-shiryen sulfonylurea, suna ɗaukar kwamfutar hannu da safe,
- 100 MG don tsananin ciwon sukari mellitus, ciki har da maganin insulin. An rarraba maganin zuwa kashi biyu.
Don metformin, kashi mafi kyau shine 2000 MG, matsakaicin shine 3000 MG.
Galvus na iya bugu akan komai a ciki ko kuma a cikakken ciki, Galvus Met - kawai tare da abinci.
Rage haɗarin sakamako masu illa
A cewar masu ciwon sukari, Galvus Met ana jure dan kadan fiye da tsarkakakkiyar metformin, amma kuma yawanci yana haifar da matsalolin narkewa: zawo, amai, da rashin jin daɗi a ciki. Karyata jiyya tare da irin wannan alamu ba shi da daraja. Don rage tsananin tasirin sakamako, kuna buƙatar ba jiki lokaci don daidaitawa da miyagun ƙwayoyi. Jiyya yana farawa da ƙarancin magani, sannu a hankali yana haɓaka shi zuwa mafi kyau.
Misali akan dabarun kara yawan kwayoyin cutar:
- Mun sayi fakiti na Galvus Met na ƙananan matakan (50 + 500), mako na farko mun ɗauki kwamfutar hannu 1.
- Idan babu matsalar narkewa, muna canzawa zuwa kashi biyu da safe da maraice. Ba za ku iya sha Galvus Met 50 + 1000 mg ba, duk da irin maganin.
- Lokacin da fakitin ya ƙare, saya 50 + 850 MG, sha Allunan 2.
- Idan sukari har yanzu yana sama da na al'ada, bayan ƙarshen marufi, za mu canza zuwa Galvus Met 50 + 1000 MG. Ba za ku iya ƙara sashi ba kuma.
- Idan biyan diyya ga ciwon sukari bai isa ba, muna ƙara sulfonylurea ko insulin.
An shawarci masu cutar Obese masu ciwon sukari su dauki matsakaicin metformin. A wannan yanayin, da maraice, suna ƙara shan Glucofage ko Siofor 1000 ko 850 mg.
Idan sukari mai azumi yana ɗaukaka, kuma bayan cin abinci mafi yawan lokuta a cikin iyakoki na al'ada, ana iya daidaita magani: sha Galvus sau biyu, da Glucofage Long - sau ɗaya da maraice a sashi na 2000 MG. Extreme Glucofage zai yi aiki da karfi duk daren, don haka tabbatar da al'ada glycemia da safe. Rashin haɗarin hypoglycemia kusan ba ya nan.
Abun dacewa
A cikin umarnin ga Galvus, ba a ambaci barasa ba, wanda ke nufin cewa barasa ba ya tasiri da ingancin allunan kuma baya kara tasirin sakamako. Amma lokacin amfani da Galvus Meta, shan giya da barasa suna hana juna aiki, tunda suna haɓaka alama da lactic acidosis. Bugu da ƙari, shan giya na yau da kullun, har ma da adadi kaɗan, ya cutar da diyya na ciwon sukari. Yawancin shan barasa ana ɗaukar saurin hadari idan har yawan maye yana da laushi. A matsakaici, 60 g na giya ne ga mata kuma 90 g na maza ne.
Tasiri akan nauyi
Galvus Met ba shi da tasiri kai tsaye a kan nauyi, amma duka kayan aiki masu aiki a cikin kayanta suna inganta haɓakar mai da rage cin abinci. Dangane da sake dubawa, godiya ga metformin, marasa lafiya masu ciwon sukari na iya rasa poundsan fam. Mafi kyawun sakamako shine a cikin masu ciwon sukari tare da yawan wuce kima da yawa da kuma dagewar insulin.
Menene Metformin?
Tushen ciwon sukari na mellitus na nau'in na biyu shine cin zarafin masu karɓa a cikin gabobin da kyallen takarda zuwa insulin, ko juriya na insulin.
Allunan da aka rufe tare da farfajiyar biconvex, kore, Allunan tare da sashi na 500 MG da 1000 MG - tare da haɗari, sashi na 850 MG - ba tare da haɗari ba.
Mun lura a gaba cewa duk wani magani da aka wajabta don ciwon sukari yana da manyan rikitattun magunguna da sakamako masu illa.
Hakanan, kayan da muke bayyanawa ba shi da haɗari, amma za mu yi magana game da wannan kaɗan.
Yana nufin magungunan hypoglycemic (biguanide aji), i.e. waɗanda suke da ikon kawar, ƙananan glucose jini.
Ana lura da wannan tasirin kusan kai tsaye bayan ɗaukar shirye-shirye waɗanda ke ɗauke da metformin hydrochloride. Wannan na faruwa ne saboda yana inganta halayyar sel zuwa insulin da cin abinci, girkewar glucose yana ƙaruwa sosai. Tabbas, a cikin yawan marasa lafiya, tare da wannan, akwai karuwa a amfani da sukari (ga wani, kusan 50%).
Wasu lokuta marasa lafiya suna gunaguni cewa maganin da aka tsara ba shi da taimako, wato, ba ya jimre wa babban aikinsa - yana daidaita glucose mai azumi. Wannan na iya faruwa saboda dalilai da yawa. Da ke ƙasa Na lissafa dalilan da yasa metformin bazai taimaka ba.
- Ba a wajabta Metformin don nuni ba
- Babu isasshen kashi
- Maganin wucewa
- Rashin cin abinci yayin shan metformin
- Banƙane guda ɗaya
Wani lokaci ya isa ya gyara rashin samun kuskure a cikin shan kuma rage darajar sukari ba zai sa a jira ku ba.
A kan wannan nake so in kawo karshen labarin na. Biyan kuɗi zuwa sabuntawar yanar gizo don samun ingantaccen bayani mai mahimmanci game da ciwon sukari da ƙari. Latsa maɓallin maɓallin zamantakewa. cibiyoyin sadarwa idan kuna son labarin kuma sun gan ku ba da daɗewa ba!
Tare da dumi da kulawa, endocrinologist Lebedeva Dilyara Ilgizovna
"Metformin" da analogues - magungunan hypoglycemic da aka wajabta a cikin lura da ciwon sukari - da farko nau'in na biyu, amma a wasu lokuta, ana ɗaukar miyagun ƙwayoyi da nau'in farko. Tun lokacin da aka gabatar da shi a cikin 1957, Metformin ya kasance mafi kyawun ƙwayoyi a cikin lura da ciwon sukari, musamman tare da rikitarwa kamar kiba.
Insulin yana inganta adon mai, kuma Metformin, yana rage yawan insulin a cikin jiki, yana taimakawa kawar dashi. Yana faruwa ne saboda wannan matakin da mutane da yawa ke amfani da Metformin azaman kwayoyin abinci.
Hanyoyin kariya na Metformin
Me ke jawo cutarwarsa?
- Magungunan yana inganta ƙwayar insulin,
- Gudanar da iko na glycemic iko,
- Fibrinolysis yana inganta,
- Ana kunna microcirculation a cikin kasusuwa na gefe,
- Damuwa ta endothelial tana raguwa
- A kan asalin metformin, hauhawar jini ya ragu,
- An rage samuwar ƙarshen kayayyakin glycation,
- Yawan yawa na jinin zinare ya ragu
- Oxidative danniya ne neutralized,
- Kyakkyawan sakamako akan atherogenesis da dyslipidemia.
Magungunan yana rage haɗarin abubuwan cututtukan zuciya a cikin masu ciwon sukari tare da cutar ta biyu, kuma tasirin ƙwaƙwalwar ƙwaƙwalwa yana ba ka damar adana sakamakon na dogon lokaci.
Jiyya tare da Metformin da abubuwan da aka samo shi yana ba da raguwa mai mahimmanci a cikin glycemia.
Idan aka kwatanta da analogs da magungunan madadin, Metformin yana da tsaka tsaki kan nauyi har ma yana taimakawa rage shi.
Tsarin maganin antidiabetic yana da kima na rage sukari, wanda ke nufin bazai taɓaka samar da sinadarin endogenous da kuma yawan fitsari ba, wanda tuni yake aiki da iyakar ƙarfinsa.
Contraindications da yiwuwar cutar
Tare da fa'idodin da ke sama na metformin, da alama rashin haɗarin cutarwa ga jikinmu daga shan waɗannan kwayoyin bai cire ba.
Babban haɗarin miyagun ƙwayoyi ya ta'allaka ne da lura da ainihin yanayin halayen masu ciwon sukari, lokacin da aka tilasta musu sarrafa matakin glycemia ta iyakance abinci na carbohydrate da kuma ƙara yawan motsa jiki.
Idan ba tare da carbohydrates ba, aiki na yau da kullun na jikin mutum, musamman kwakwalwa, wanda ake amfani da shi don cin abinci na musamman tsarkakakke - glucose, ba shi yiwuwa. Idan an rage yawan sukari da yawa, to, matakinsa a cikin jini zai ragu zuwa matakai masu mahimmanci, wanda hakan zai haifar da rashin lafiya.
Amma a jikin mu akwai ragowar levers don tsara irin wannan gazawar, wanda zai iya rama wani rashin abu mai wuce kima. Ofayan wannan damar don haɗarin hypoglycemia shine hepatic gluconeogenesis, lokacin da glucagon ya fara samar da farfadowa daga glucose daga cikin hanta da aka adana a baya, amma lokacin da aka ɗauki wannan maganin wannan tsari yana rage gudu!
Lactic acidosis (ko lactic acidosis, lactic acid coma) yana haɓaka da sauri tare da matsalolin da ke faruwa tare da kodan (tare da ciwan mai cutar ciwan, wanda ke haɓakawa cikin wani yanayi na rashin aiki na koda koda), tunda metformin hydrochloride ya tara a cikin glandon salivary, tsoka, hanta, da ƙodan koda. Kuma aka raba ta da kodan.
Idan aikinsa ya rushe, kashi 90% na wannan magungunan suna ci gaba da canzawa a jikin mutum. Amma tare da wannan duka, rikicewar daidai da haɗari a cikin ciwon sukari - ketoacidosis, a matsayin mai mulkin, ba ya haɓaka.
Sabili da haka, yana da haɗari don ɗaukar kwayoyi masu dauke da metformin idan akwai matsala na rashin ƙoshin koda ko wata matsala tare da kodan, amma yawancin endocrinologists har yanzu suna ba da shi, suna cewa rage ƙwayar cutar glycemia da yaƙi juriya insulin shine mafi mahimmanci, saboda tare da ƙara matakan sukari na jini, rikitarwa mai yawa, wanda haifar da karuwar mace-macen masu ciwon sukari.
A cikin al'adar kasa da kasa, ana bada magunguna masu dauke da maganin metformin kai tsaye bayan an yi gwajin cuta kuma yana da karfin gaske tsawanta da masu cutar siga. A Rasha, a matsayin mai mulkin, ana tsara shi sau da yawa a cikin matakan ci gaba na cutar, lokacin da metformin ya zama wani ƙarin dalili don lalata yanayin yanayin marasa lafiya ban da ƙara rikicewar cututtukan ciwon sukari a daidai lokacin da farkon yanayinsa (a cikin ƙananan allurai) zai iya inganta lafiya da jinkirta makawa.
Tare da wani nau'i mai laushi na ciwon sukari, juriya da kyallen takaddun insulin-mamaye ya mamaye, saboda haka, babban magani shine rage juriya insulin. Abin da gwarzonmu zai iya shawo kan sauƙi ko da a cikin ƙananan allurai, waɗanda ba su da ikon cutar da jikin mutum sosai.
Amma, abin takaici, ajiyar ma'anar insulin insulin a cikin nau'in ciwon sukari na 2 ya ƙare (i.e., insulin ba a samar da kansa ba a cikin girman da ake buƙata), to, an tilasta likitoci don ƙara ƙwayar insulin insulin zuwa far - waɗannan sune sulfanilamides.
Bayan haka, idan sun tabbatar da rashin inganci, to, ana shirya shirye-shiryen insulin a cikin jiyya, yawanci a hade tare da kwayoyi waɗanda ke kara haɓaka ƙwayoyin insulin-insulin zuwa insulin (wannan shine babban halinmu tare da ku).
Sauran sakamako masu illa sun haɗa da:
- matsalolin gastrointestinal (tashin zuciya, amai, amai, gas, gudawa)
- anorexia
- take hakkin dandano (alal misali, dandano mai karawa a cikin abincin da aka cinye)
- karancin bitamin B12 (sabili da haka, ana bada shawarar ƙarin ci)
bitamin don ciwon sukari
Nawa
Ana samun magungunan a cikin nau'ikan allunan. Allunan ana kunshe-kunshe a fakiti mai bakin ciki wanda aka yi da polyvinyl chloride da kuma tsare aluminium. Kowane fakitin ya ƙunshi Allunan 10.
Ana sanya fakitoci shida cikin kwali na kwali, wanda ya ƙunshi umarnin don amfani. Akwatin kwali na miyagun ƙwayoyi ya ƙunshi allunan 60.
Adana kwayoyi a wurin da aka kiyaye shi daga hasken rana kai tsaye a zazzabi da bai wuce digiri 25 Celsius ba. Dole ne a adana magungunan ba tare da isa ga yara ba.
Rayuwar rayuwar shiryayye na samfurin likita shine shekaru uku. Ana sayar da maganin a cikin kantin magunguna ta hanyar sayan magani.
Yawancin bita-bita da marasa lafiya ke amfani da wannan magani suna da inganci. Bayyanuwa na sake dubawa mara kyau shine yawancin lokuta ana danganta su da keta umarnin umarnin amfani da miyagun ƙwayoyi ko kuma idan ya keta shawarar da aka karɓa daga likitan halartar. Sau da yawa akwai sake dubawa na marasa lafiya, wanda ke nuna cewa yawan amfani da magunguna yana rage nauyin jiki.
Babban kamfanin samar da magunguna a cikin Tarayyar Rasha shine Ozone LLC.
Farashin magani a kan ƙasa na Tarayyar Rasha ya dogara da cibiyar sadarwa na kantin magani da yankin da ke sayar da magani. Matsakaicin farashin magani a cikin Tarayyar Rasha ya tashi daga 105 zuwa 125 rubles a kowane fakiti.
Hanyoyin da aka fi sani dasu na Metformin 500 a cikin Federationungiyar Rasha sune waɗannan:
- ,
- Glycon
- Glyminfor,
- Glyformin
- Glucophage,
- Glucophage Tsawon,
- Methadiene
- Metospanin
- Metfogamma 500,
- Metformin
- Karin Richter,
- Metformin Teva,
- Metformin hydrochloride,
- Nova Sanda
- Lankaranna,
- Siofor 500,
- Sofamet
- A tsari,
- Kayan tsari.
Tsarin da aka ambata ana amfani da Metformin iri daya ne a tsarin tsari da kuma bangaren aiki.
Yawancin analogues na ƙwayoyin cuta na Metformin suna ba da damar, idan ya cancanta, likitan halartar don sauƙaƙe zaɓin maganin da ake buƙata kuma maye gurbin Metformin tare da wani na'urar likita. Game da yadda Metformin ke aiki a cikin ciwon sukari, ƙwararren masani zai faɗi a cikin bidiyo a wannan labarin.
Kudin maganin yana daga 100 zuwa 250 rubles, gwargwadon abun da ke cikin abu mai aiki.
Kasuwancin magani yana ba da alluna da yawa tare da kayan aikin da aka bayyana.
Duk da bambancin nau'ikan kayan taimako, magungunan ƙwayoyin cuta ba su da tsada sosai .. Misali, farashi a Rasha ya kai 90 zuwa 260 rubles.
Farashin Metformin daga wasu kamfanonin magunguna na kasashen waje ba su bambanta da yawa.
Kudin Metformin daga masana'antun kasashen waje daban-daban sune:
- Slovakia - daga 130 zuwa 210 rubles.
- Harshen Harshen - daga 165 zuwa 260 rubles.
- Poland - daga 75 zuwa 320 rubles.
Shirye-shiryen dauke da metformin hydrochloride galibi suna zuwa ga tsakiyar aji. Kuna iya ajiye kuɗi ta hanyar sayen magungunan masu ciwon sukari akan layi. Farashin magani na Metformin ya dogara da sashi:
- 500 MG (Allunan 60) - daga 90 zuwa 250 rubles,
- 850 MG (Allunan 60) - daga 142 zuwa 248 rubles,
- 1000 mg (60 Allunan) - daga 188 zuwa 305 rubles.
Kamar yadda kake gani, farashin wakilin hypoglycemic wakili bai da girma sosai, wanda shine babban ƙari.
Nazarin haƙuri game da miyagun ƙwayoyi galibi tabbatacce ne. Metformin yana rage matakan sukari daidai kuma baya haifar da hypoglycemia. Likitocin sun kuma amince da amfani da magungunan maganin cututtukan cututtukan fata. Yin amfani da Metformin na yau da kullun don hana cutar cututtukan zuciya ya biya.
Wasu mutanen da ba su da ciwon sukari suna shan magani don rage nauyin su. Masana sun bada karfi da bayar da shawarar amfani da wannan magani don asarar nauyi ga mutane masu lafiya.
Matsakaicin farashin METFORMIN a cikin kantin magani (Moscow) 110 rubles.
Matsakaicin farashin Allformin Allunan a cikin kantin magani a Moscow ya bambanta daga 117-123 rubles.
Glucophage (Metformin) don asarar nauyi. Lokacin da ba za a iya ɗauka ta kowane yanayi ba
Masana sun yarda da wannan kayan aiki don maganin cututtuka daban-daban.
Bobkov E.V., babban likita, dan shekara 45, Ufa: "Wani ingantaccen magani ne wanda ake amfani dashi don maganin cututtukan type 2."
Danilov S.P., babban Likita, dan shekara 34, Kazan: “A cikin shekarun nan, ya nuna ingancinta a yakar masu wuce gona da iri. Yana taimakawa a cikin dan kankanin lokaci don cimma sakamako mai kyau. "
Dmitry, dan shekara 43, Vladivostok: “Ina fama da ciwon sukari na 2. Na ɗanɗana wannan maganin tare da allurar insulin har kusan shekara guda. Yana rage glucose na jini. ”
Vladimir, ɗan shekara 39, Ekaterinburg: “Na daɗe na ɗauki Glibenclamide, amma daga baya aka ba da umarnin Metformin. Ana ɗaukar shi cikin nutsuwa, kuma sukari na jini ya koma daidai, yanayin ya zama mai kyau. ”
Svetlana, dan shekara 37, Rostov-on-Don: “Na sayi wannan maganin ne bisa shawarar masanin abinci mai gina jiki. Ban ji cikakken sakamako ba. ”
Valeria, 'yar shekara 33, Orenburg: “Tun suna yara, masu fama da kiba. Likitan da ke halartar ya shawarci Metformin. Bayan wata daya, na daina shan shi, saboda shan azaba da zafin rai da tashin zuciya. "
Metformin yana ba da tsayayyen tasirin sukari a kusan duk marasa lafiya. Wani mummunan rauni na maganin shine yawan sakamako masu illa daga narkewa.
Don kawar dasu, Ina bayar da shawarar sauyawa zuwa allunan jinkirin-jinkiri, shan su kafin lokacin bacci. Tea ko ruwa tare da lemo yana taimakawa sosai daga cutar sanyin safiya da dandano a cikin bakin.
Yawancin lokaci ina tambaya don makonni 2, a cikin wannan lokacin mafi yawan lokuta bayyanar cututtuka sun ɓace. Na ɗanɗani haƙuri da yawa sau da yawa, a cikin dukkan lokuta an tsawaita zawo.
Na kasance shugabana masu ciwon sukari shekaru da yawa kuma koyaushe ina rubuto Metformin a cikin halarta na farko na cutar 2. Kwatantawa matasa marasa lafiya da ke da nauyi sosai suna da kyakkyawan sakamako.
Na tuna shari'ar guda, wata mace ta zo da nauyin kilogiram 150 tare da nauyin kiba a ciki. Ta yi korafi game da rashin iya nauyi, duk da cewa adadin kuzari na yau da kullun, a cewarta, kodayake ba ta kai 800 kcal.
Gwaje-gwaje sun nuna rashin haƙuri na glucose. Na rubuta kawai multivitamins da Metformin, sun yarda cewa mai haƙuri zai kara yawan adadin kuzari zuwa 1,500 kuma zai fara ziyartar tafkin sau uku a mako.
Gabaɗaya, "tsari ya fara" a cikin wata guda. Yanzu ya riga ya cika kilogiram 90, ba zai tsaya a nan ba, an cire maganin ciwon suga.
Ban yi la'akari da irin wannan abin yabo ba kawai magani ne, amma Metformin ya ba da ƙarfin farko.
Lokacin da ake rubuta Metformin, koyaushe nace cewa ya fi kyau ka ɗauki magani na ainihi. Sakamakon yin amfani da kwayoyin halitta na Indiya da Sinanci koyaushe yana da muni. Magungunan Turai da na gida sune zaɓi mai kyau idan baza ku iya samun Glucophage ba.
- Shin za a iya amfani da metformin don hana ciwon sukari?
- Nau'in maganin ciwon sukari na 2
- Yadda ake ɗaukar metformin a cikin nau'in ciwon sukari na 2
- Foreng tare da ciwon sukari mellitus
Janar halaye na miyagun ƙwayoyi
Godiya ga vildagliptin, mummunan tasirin dipeptidyl peptidase-4 an rage shi, kuma samar da GLP-1 da HIP, akasin haka, yana haɓaka. Lokacin da matakan waɗannan abubuwan da ke cikin jini ya tashi, vildagliptin yana iya inganta yiwuwar ƙwayoyin beta zuwa ga glucose da aka samar, ta haka ne yake haɓaka samar da ƙwayar suga. Ya kamata a lura cewa ƙimar haɓaka aikin beta sel ya dogara da matakin lalacewarsu. Sabili da haka, a cikin mutane masu matakan sukari na yau da kullun, vildagliptin ba ya shafar samar da insulin kuma ba shakka, samar da glucose.
Bangaren mai aiki yana kara yawan GLP-1 kuma nan da nan yana kara karfin jijiyoyin sel na islet din kayan aiki zuwa glucose. Sakamakon haka, samar da glucagon yana ƙaruwa. Decreasearin raguwa a cikin matakin ƙaruwa yayin cin abinci yana haifar da karuwa a cikin ƙwayar jijiyoyin sel zuwa haɓakar ƙwayar sukari.
A yayin haɓaka mai sauri cikin matakan sukari, matakan glucagon da matakan insulin, wanda ke dogara kai tsaye kan yawan haɓaka GLP-1 da HIP, aiwatar da samar da glucose a cikin hanta yana rage gudu duka yayin cin abinci da bayan sa, wanda ke haifar da raguwar tarin glucose a cikin jini. Ya kamata a lura cewa daɗaɗɗaɗaɗaɗaɗaɗaɗɗun abubuwan da ke cikin GLP-1 na iya rage aiwatar da ɓacin rai, kodayake a aikace magungunan ba su tsokane ci gaban irin wannan sabon abu ba.
Cikakken amfani da abubuwa guda biyu - metformin da vildagliptin, har ma sun fi dacewa a sarrafa matakin glycemia a cikin masu ciwon suga na tsawon awanni 24.
Umarnin don amfani da allunan
Cin abinci ba ya shafar amfani da miyagun ƙwayoyi Galvus ko Galvus Met.
Kafin amfani da maganin, ya zama dole a nemi taimakon ƙwararrun masani waɗanda za su ƙayyade sashi daban.
Jagororin da aka haɗa don maganin Galvus 50 MG na nuna magunguna waɗanda likita da masu halartar za su iya daidaitawa:
- Tare da monotherapy ko a hade tare da maganin insulin, thiazolidinedione, metformin - 50-100 mg.
- Masu fama da cutar sikari wadanda suka kamu da cutar siga suna daukar 100 MG kowace rana.
- Amincewa da vildagliptin, abubuwan asali na sulfonylurea da metformin - 100 MG kowace rana.
- Hadaddun amfani da sulfonylurea da kayan aikin Galvus suna ba da shawarar kashi 50 na MG kowace rana.
- Idan mai ciwon sukari yana da matsakaiciyar matsakaiciyar ƙwayar cutar sankara da tahaima, ƙimar yau da kullun shine 50 MG.
Saka ya ƙunshi bayanin cewa yakamata a ɗauki allurai 50 MG a lokaci da safe, kuma 100 MG ya kasu kashi biyu - da safe da maraice.
Dos na miyagun ƙwayoyi Galvus Met shi ma likita ya ƙaddara shi, la'akari da matakin sukari da haƙuri da abubuwan da miyagun ƙwayoyi ke ba wa mara haƙuri. Jagorar tana ba da shawarar matsakaita masu zuwa:
- tare da rashin amfanin yin amfani da vildagliptin, ana bada shawarar shan 50/500 mg sau biyu a rana,
- idan amfani da metformin ba shi da tasiri, ɗauki 50/500 mg, 50/850 mg ko 50/1000 mg sau biyu a rana, gwargwadon metformin da aka yi amfani da shi a baya,
- tare da haɗuwa mara amfani na vildagliptin da metformin, ana amfani da 50/500 mg, 50/850 mg ko 50/1000 mg sau biyu a rana, gwargwadon abubuwan da aka yi amfani da su,
- yayin lokacin farkon magani tare da miyagun ƙwayoyi saboda rashin daidaituwa na abinci da motsa jiki, ɗauki 50/500 mg sau ɗaya a rana,
- a hade tare da maganin insulin da abubuwan da suka samo asali na sulfonylurea, sashi na vildagliptin shine 50 MG sau biyu a rana, kuma metformin iri ɗaya ne kamar yadda yake tare da monotherapy.
An haramta yin amfani da miyagun ƙwayoyi don masu ciwon sukari da ke fama da gazawar koda da sauran cututtukan wannan sashin. Bugu da kari, an wajabta kulawa ta musamman ga marasa lafiya na nau'in tsufa (sama da shekaru 65), tunda yawanci suna da raguwa a cikin aikin koda.
Likita na iya kara yawan magunguna, kodayake, haramun ne a shiga cikin jinyar da kanka, wannan na iya haifar da sakamako da ba za a iya jurewa ba.
Kudin, sake dubawa da kuma daidaitawa
Wanda ya kirkiro maganin shine kamfanin Switzerland na Novartis, wanda ke samar da magani tare da vildagliptin ko kuma hade da vildagliptin tare da metformin.
Ana iya ba da umarnin magunguna ta hanyar kan layi ko kawai zuwa kantin magani mafi kusa. Farashin magani ya dogara da irin sakinsa. Matsakaicin farashi kamar haka:
- Galvus 50 MG (Allunan 28) - 765 rubles.
- M Galvus Met 50/500 MG (Allunan 30) - 1298 rubles.
- M Galvus Met 50/850 MG (Allunan 30) - 1380 rubles.
- Galvus Met 50/1000 MG (Allunan 30) - 1398 rubles.
Kamar yadda kake gani, miyagun ƙwayoyi basu da arha. Ba kowa ba ne zai iya wadatar magani na yau da kullun tare da waɗannan magungunan, don haka akwai buƙatar zaɓar magunguna masu kama, waɗanda za a tattauna daga baya.
Amma game da ra'ayi a kan miyagun ƙwayoyi Galvus, galibi suna da inganci. Binciken yawancin marasa lafiya da ke shan magani ya nuna cewa bayan watanni 1-2 na ɗaukar Galvus, alamu na glucose sun koma al'ada. Bugu da kari, masu ciwon sukari suna son hakan yayin amfani da miyagun ƙwayoyi kuna iya cin abinci da aka haramta a baya. Galvus Met, godiya ga metformin, yana taimakawa rasa karin fam miliyan 3-4 a cikin marasa lafiya tare da kiba. Koyaya, maganin yana da babbar hasara - babban kuɗin sa ne.
Idan an hana mai haƙuri yin amfani da Galvus saboda contraindications ko sakamako na gefen, likita ya tsara wani magani. Wadannan na iya zama alamomi, watau wadancan samfuran wadanda ke dauke da abu guda mai aiki, bambanci shine kawai a cikin wasu abubuwan hadewa. Galvus Met shine kawai ma'anar Galvus; waɗannan shirye-shirye biyu ne waɗanda ke ɗauke da vildagliptin.
Koyaya, waɗannan magunguna suna da magunguna masu yawa waɗanda suke da kama da sakamako na warkewa, wanda za a yi bayani daga baya.
