Mefarmil na miyagun ƙwayoyi: umarnin don amfani

Magungunan yana cikin rukunin biguanides, abu mai aiki shine dimethyl biguanide. Sami shi daga tsire Galega officinalis. Metformin ya shiga tsakani tare da aiki na glucose ta hanta (tsarin gluconeogenesis), don haka rage matakan sukari na jini. A layi daya tare da wannan, miyagun ƙwayoyi suna ƙara ƙarfin jiɓin masu karɓar insulin, inganta sha, yana inganta ingantaccen hadawar abu mai guba, ƙara yawan amfani da glucose, da rage shaye-shayen daga narkewa.

Kayan aiki yana taimakawa rage rage yawan hodar iblis a cikin jini, rage cholesterol da low lipoproteins mai yawa, ta haka yana hana canje-canje na cututtukan jini. Normalizes jini coagulability, inganta ta rheological Properties, game da shi taimaka rage hadarin thrombosis.

Binciken Endocrinologists na Metformin ya tabbatar da bayani cewa yana taimakawa rage nauyi cikin kiba.

Analogs na Metformin

Metformin analogues sun hada da magunguna masu zuwa: Glucofage, Metformin-BMS, Metformin hydrochloride, Metformin-vero, Metformin-Richter, Formmetin, Formin Pliv, Gliformin, Glucofag, Vero-Metformin Novoformin, Metospanin. Metfogamma, Siofor, Glycomet, Dianormet, Orabet, Bagomet, Gliminfor, Glycon.

Daga hangen nesa game da aikin harhada magunguna, analog na maganin Metformin shine insulin.

Alamu don amfani

Amfani da Metformin an nuna shi a cikin lura da ciwon sukari na type 2 tare da adana aikin koda, da kuma yanayin ciwon sukari. Nunin kai tsaye don amfani shine ciwon sukari na 2, tare da kiba.

Hakanan ana amfani dashi azaman ɓangaren rikicewar jiyya a cikin lura da ƙwayar ciki na ciki-visceral.

Yayin amfani da shi a cikin aikin asibiti, sake duba bayanan Metformin sun kasance masu kyau cewa bayan gudanar da gwaji na asibiti wanda ya tabbatar da su, a cikin 2007 an ba da shawarar yin amfani da maganin a cikin ilimin yara don lura da ciwon sukari na 1, a matsayin haɗin kai ga ilimin insulin.

Umarnin don amfani da Metformin

Ana ɗaukar allunan Metformin a hankali bayan cin abinci, shan ruwa mai yawa. Magunguna na farko da na farko sune 1000 MG kowace rana, sama da tsawon makonni 1-2 suturar ta ƙara ƙaruwa, an daidaita darajar ta a ƙarƙashin kula da bayanan dakin gwaje-gwaje akan matakin glucose a cikin jini. Matsakaicin da aka yarda da shi shine 3000 MG kowace rana. Ana iya amfani da kashi na yau da kullun a lokaci ɗaya, amma a farkon farfajiya, a lokacin daidaitawa, ana bada shawara don rarraba shi zuwa allurai 2-3, wanda ke taimakawa rage sakamako na miyagun ƙwayoyi a kan ƙwayar gastrointestinal.

Ana lura da mafi girman yawan ƙwayoyi a cikin jini na jini 2.5 sa'o'i bayan gudanarwa, bayan sa'o'i 6 yana farawa. Bayan kwanaki 1-2 na cin abinci na yau da kullun, an kafa ƙwaƙwalwar ƙwayar cuta a cikin jini, bisa ga sake dubawa, Metformin yana fara samun sakamako mai ganuwa makonni biyu bayan farawar gudanarwa.

Tare da yin amfani da Metformin da insulin gabaɗaya, kulawar likita ya zama dole, tare da ɗimbin insulin a cikin asibiti.

Side effects

Lokacin da aka yi amfani da shi bisa ga umarnin, mafi yawan lokuta ana haƙuri da haƙuri sosai, marasa lafiya suna haifar da sakamako masu illa. Idan akwai, to, a matsayin mai mulkin, ana danganta su ko dai tare da rashin yarda da miyagun ƙwayoyi, ko hulɗa tare da wasu kwayoyi, ko kuma yawan wucewa.

Dangane da sake dubawa, Metformin mafi yawan lokuta yana haifar da rikicewar narkewa, yana bayyana ta hanyar dyspepsia a cikin nau'i ɗaya ko wata, a matsayin ɗayan alamun bayyanar lactic acidosis. Yawanci, ana ganin irin waɗannan alamun a farkon hanya na magani tare da miyagun ƙwayoyi, kuma bayan tsawon lokacin wucewa don daidaitawa. Dangane da umarnin, Metformin a wannan yanayin dole ne a yi amfani dashi a cikin rage ragewa, tare da lactic acidosis mai zafi, an soke maganin.

Tare da yin amfani da tsawan lokaci, Metformin yana ba da gudummawa ga rushewar musayar bitamin B12 (cyancobalamin), yana hana shan hanji a cikin hanji, wanda zai iya haifar da alamun cutar rashin ƙarfi ta B12. Wannan yanayin yana buƙatar gyaran magani.

Tsarin maganin hana daukar ciki

Ana nuna waɗannan contraindications a cikin umarnin Metformin:

• Lactic acidosis na yanzu ko na baya
• Yanayin precomatous
• Rashin hankali ga kowane ɓangare na maganin,
• Paarancin aikin na yara, da kuma cututtukan haɗin da za su iya haifar da irin wannan cin zarafin,
• Adrenal kasawa,
• Rashin hanta
• Kafar ciwon sukari
• Dukkanin yanayin da ke haifar da bushewa (amai, gudawa) da hauhawar jini (rawar jiki, gazawar zuciya),
• Al'adar fata Ya kamata a ɗauka a cikin zuciya cewa koda amfani da haɗin gwiwa guda na Metformin da barasa na iya haifar da rikice-rikice na rayuwa,
• Cutar cututtuka a cikin lokacin m, tare da zazzabi,
• Cututtukan cututtukan daji a cikin mataki na lalata,
• Jinyar tiyata da kuma aikin tiyata,
• Rashin shayarwa

Cutar ciki, kamar ƙuruciya, ba a ɗauka cewa cikakkiyar contraindication ga shan miyagun ƙwayoyi, tunda yana yiwuwa a tsara Metformin don kula da cututtukan ƙwayar cutar hanji da na yara, duk da haka, a cikin waɗannan halayen, aikin far yana faruwa a ƙarƙashin kulawa na likita.

Umarni na musamman

Tare da Metformin monotherapy, babu wani haɗarin haɓakar hypoglycemia, irin wannan haɗarin ba a cire shi a cikin hadadden hanyoyin maganin ciwon sukari, kuma ya kamata a faɗakar da mai haƙuri game da wannan. An haramta amfani da wannan magani da abubuwan radiopaque abubuwa masu dauke da aidin. Duk wani amfani da Metformin da wani magani yana buƙatar kulawa da likita. A lokacin tiyata, ana soke aikin magani na kwanaki 2-3 daga cikin bayan aikin. Umarni na Metformin yana ba da tsarin rage cin abinci a duk lokacin aikin jiyya, wanda ke guje wa kololuwar kaifi da saukad da shi a cikin glucose na jini, yana haifar da tabarbarewa cikin walwala.