Menene Meldonium don? Umarnin, farashi da bita

• allura: bayyananna, ruwa mara launi (5 ml kowane cikin gilashin gilashin launuka marasa launi tare da aya da ƙararrawa / kink ring, ko kuma ba tare da aya da ƙararrawa ba / kink, 5 ampoules a cikin farkakkken fitila / kwali mai kwalliya tare da sel, a cikin kwali ko 2 fakiti / kwandon shara, zuwa ampoules wanda akwai zobe mai kink ko aya da daraja, ampoule wuka / mai ruwan walwa a ciki a cikin kayan),
• capsules: gelatin mai wuya, 250 MG - girman No. 1, tare da jiki da farin hula, 500 MG - girman No. 00, tare da farin jiki da rawaya mai launin rawaya, abubuwan da ke ciki - farin farin hygroscopic crystalline foda tare da takamaiman wari (10 kowane a cikin kwane-kwane fakitin kwayar halitta, a cikin wani kwali na kwali na fakiti 3 ko 6).

Kowace fakitin ya ƙunshi umarnin don amfani da Meldonium.

Abun ciki na 1 ml na bayani:

• abu mai aiki: meldonium dihydrate - 100 MG,
• bangaren taimako: ruwa don yin allura - har zuwa 1 ml.

Abun ciki 1 kawa:

• abu mai aiki: meldonium dihydrate - 250 ko 500 MG,
• karin abubuwan taimako: stearate alli, silicon dioxide (aerosil), sitacin dankalin turawa,
• Tsarin kwalliya na 250 mg kwalliya: jiki da murfi - gelatin da titanium dioxide,
• Hadaddiyar kwandon kwalliya na 500 MG: harka - gelatin da titanium dioxide, hula - gelatin, titanium dioxide, dyes, faɗuwar rana rawaya da rawaya quinoline.

Pharmacodynamics

Abubuwan da ke aiki da maganin - meldonium dihydrate, analog ne mai tsari na gamma-butyrobetaine. Kayan yana hana tarawa a sel wanda aka kunna siffofin mayuka na acid (wanda aka samo na acylcarnitine da acylcoenzyme A), yana rage jigilar kitse mai kitse ta hanyar membranes, yana rage hadaddun carnitine, kuma yana hana gamma-butyrobetaine hydroxynase. Sakamakon raguwa a cikin taro na carnitine, akwai karuwar haɗin gamma-butyrobetaine - wani abu wanda yake da kaddarorin vasodilating.

A cikin yanayin ischemia, Meldonium yana dawo da daidaituwa na tafiyar matakai na isar da oxygen zuwa sel da kuma yawan amfani da shi, sannan kuma yana hana cin zarafin zirga-zirga enzyme na angiotensin (ATP). Bugu da ƙari, ƙwayar tana kunna tsarin glycolysis, ci gaba ba tare da ƙarin amfani da oxygen ba.

Saboda yanayin aikin da aka bayyana, Meldonium yana da tasirin magunguna masu zuwa: yana ƙara ƙarfin aiki, rage alamun bayyanar damuwa ta jiki da ta tunani, yana kunna ƙwayoyin cuta da ƙyalƙwalwar ɗan adam, kuma yana da kima na zuciya.

A cikin lalacewa mai rauni na ischemic myocardial, miyagun ƙwayoyi suna hana samuwar yankin necrotic kuma yana rage tsawon lokacin farfadowa. Dangane da hatsarin ischemic cerebrovascular (duka biyu da mara nauyi), yana haɓaka sake rarraba jini a madadin wurin ischemic kuma yana inganta haɓakar jini a cikin zuciyar ischemia. Tare da rashin karfin zuciya, yana kara yawan kwanciyar hankali na mutum, yana rage yawan tashin hankalin angina, da kuma kara karfin motsa jiki.

An tabbatar da tasirin Meldonium dangane da batun cutar dystrophic da jijiyoyin bugun gini daga cikin asusun.

Magungunan yana da tasiri na tonic akan tsarin juyayi na tsakiya. Yana kawar da rikice-rikice na aiki na tsarin autonomic da juyayi mai juyayi yayin lokacin cirewa a cikin marasa lafiya tare da barasa.

Pharmacokinetics

Tare da gudanarwa na ciki, meldonium an san shi da cikakken bioavailability - 100%. Matsakaicin maida hankali (Cmax) a cikin plasma an kai shi kai tsaye bayan allura.

Lokacin da aka yi magana da baki, bioavailability na meldonium shine 78%. An lura da Cmax a cikin plasma 1-2 sa'o'i bayan ɗaukar capsule.

Magungunan yana metabolized don samar da manyan metabolites guda biyu waɗanda kodan ke cirewa. Cire rabin rayuwar (T_1/2) na iya zama daga 3 zuwa 6 hours

Alamu don amfani

Don bayani da maganin kawu:

• cututtukan zuciya da jijiyoyin zuciya (angina pectoris, infarction myocardial), gazawar zuciya mai rauni, rashin lafiyar zuciya a bango na bayyananniyar bayyananniyar rashin kunya - a zaman wani bangare na hadaddiyar farjin,
• m da kuma na kullum hatsarori na cerebrovascular kasawa, bugun jini) - a matsayin wani ɓangare na hadaddun far,
• karban ciwo a cikin matsalar shan giya - baya ga takamaiman magani na rashin shan giya,
• rage aiki, ƙwaƙwalwa da raunin jiki (gami da masu motsa jiki).

Bugu da ƙari, don maganin - a zaman wani ɓangare na ƙwaƙwalwar jiyya:

• hemophthalmus da kuma na baya bashin daban-daban etiologies,
• retinopathies na daban-daban etiologies (ciki har da masu ciwon sukari da hauhawar jini),
• thrombosis daga cikin jijiya na tsakiya da kuma rassanta.

Additionallyarin ƙari ga capsules: lokacin aikin (don hanzarta hanzarta tsarin gyaran).

Contraindications

• pressureara yawan matsin lamba (sakamakon raunin da ya haifar da ciwan ciki),
• shekaru zuwa shekaru 18
• ciki
• lactation
• rashin hankali ga abubuwan da ke cikin miyagun ƙwayoyi.

Ya kamata a yi amfani da Meldonium tare da taka tsantsan a cikin marasa lafiya da cututtukan hanta da / ko cutar koda.

Magani don allura

Ana gudanar da injections na Meldonium intramuscularly (i / m), cikin cikin ciki (i / v) ko parabulbarno.

An ba da shawarar gabatarwar miyagun ƙwayoyi da safe, saboda yiwuwar haɓaka sakamako mai ban sha'awa.

Hanyar gudanarwa, adadin Meldonium da tsawon lokacin amfani dashi, likita ya saita daban bisa ga alamu da tsananin yanayin.

Cikakken farji na cututtukan zuciya:

• myocardial infarction: iv a cikin jirgin sama na 500-1000 MG a rana daya ko biyu injections,
• tsayayyen angina pectoris tare da cututtukan zuciya, cututtukan zuciya da na zuciya da rashin lafiya sakamakon matsalar jijiyoyin jini: iv a cikin jet na 500-1000 MG kowace rana a cikin daya ko biyu injections don kwanaki 10-14, sannan an tura mai haƙuri zuwa nau'in maganin. Babban aikin jiyya shine makonni 4-6.

Hadewar magani don haɗarin ƙwayar cuta:

• m lokaci: iv 500 MG sau ɗaya a rana don kwanaki 10 tare da kara canja mai haƙuri zuwa nau'in maganin. Jimlar magani shine makonni 4-6,
• nau'in cuta na yau da kullun: iv 500 MG sau ɗaya a rana don kwanaki 10, biye da mai haƙuri zuwa nau'in maganin. Babban maganin shine makonni 4-6, akan shawarar likita sau 2-3 a shekara ana maimaita kwasa-kwasan karatun.

• rikicewar ophthalmic: parabulbarno 50 MG a hanya na kwanaki 10,
• rashin shan giya mai lalacewa: in / a ciki ko cikin / m a 500 MG sau 2 a rana don kwanaki 7-10,
• saukarwar tunani da ta jiki: a / cikin ko cikin / m 500 MG 1 sau ɗaya kowace rana don kwanaki 10-14. Idan ya cancanta, maimaita hanya bayan makonni 2-3.

A cikin nau'in capsules, ya kamata a ɗauka meldonium a baki kafin abinci.

Nagari hanyoyin bada shawara:

• rikicewar ƙwayar jini zuwa kwakwalwa: 500-1000 MG kowace rana (zai fi dacewa a farkon rabin rana) don makonni 4-6,
• rashin lafiyar zuciya, tsayayyen angina (a zaman wani yanki na hadaddun jiyya): 500-1000 MG a rana a daya ko biyu allurai na makonni 4-6,
• katin ƙwaƙwalwar ƙwaƙwalwa sakamakon disystmonal myocardial dystrophy: 250 mg sau 2 a rana don kwanaki 12,
• kariyar cutar barasa: 500 MG sau 4 a rana don 7-10 kwana,
• rage aiki, nauyin kwakwalwa da na jiki, hanzarta farfadowa a cikin aikin bayan: 250 mg sau 4 a rana don kwanaki 10-14, idan ya cancanta, maimaita magani bayan makonni 2-3,
• zazzage jiki a cikin 'yan wasa: 500-1000 MG sau 2 a rana kafin a fara horarwa na kwanaki 14-21 a lokacin shiri, kwanaki 10-14 a lokacin gasar.

Kayan magunguna

Hanyoyin haɓaka ƙwayar cuta, anama gamma-butyrobetaine. Yana hana gamma-butyrobetaine hydroxynase, yana hana haɗin carnitine da jigilar daskararren sarkar acid ta hanyar membranes, kuma yana hana tara nau'ikan kitse na unoxidized mai mai a cikin sel - abubuwan da ke faruwa na acylcarnitine da acylcoenzyme A.

A karkashin yanayin ischemia, yana dawo da daidaituwa na tafiyar matakai na isar da oxygen da yawan amfani da shi a cikin sel, yana hana cin zarafin jigilar jigilar ATP, kuma a lokaci guda yana kunna glycolysis, wanda ke gudana ba tare da ƙarin amfani da oxygen ba.

Sakamakon raguwa a cikin taro na carnitine, gamma-butyrobetaine tare da kaddarorin vasodilating yana haɓaka mai ƙarfi. Hanyar aiki yana ƙayyade bambancin tasirin magunguna: haɓaka haɓaka, rage alamun damuwa da damuwa na jiki, kunna nama da rigakafin ƙwaƙwalwar mutum, tasirin cutar zuciya.

Tasiri

Game da mummunar cutar ischemic a cikin myocardium, yana rage jinkirin samuwar yankin necrotic kuma yana gajarta lokacin murmurewa. Tare da rashin karfin zuciya, yana kara yawan kwanciyar hankali na mutum, yana kara karfin motsa jiki, da kuma rage yawan kamuwa da cutar angina.

A cikin mummunar cuta da rashin lafiyar ischemic na wurare dabam dabam na haɓakar cerebral yana inganta wurare dabam dabam na jini a cikin ischemia, yana ba da gudummawa ga sake rarraba jini a madadin yankin ischemic. Inganci ga cututtukan jijiyoyin bugun gini da na dystrophic na fundus.

Yana da sakamako na tonic akan tsarin juyayi na tsakiya, yana kawar da rikice-rikice na aiki na tsarin juyayi a cikin marasa lafiya tare da shan barasa tare da ciwo na cirewa.

Menene Meldonium don?

Manuniya don amfani sun haɗa da hadadden far:

• kangin aiki,
• karban ciwo a mahaukaci,
• Ciwon zuciya,
• rage aiki
• hatsarori na ciki,
• dishormonal cardiomyopathy,
• Gyaran bayan aikin asibiti

Abin da Parabulbar gwamnatin taimaka daga:

• retinal thrombosis,
• retinopathies (masu ciwon sukari da hauhawar jini),
• bashin jini,
• cuta na cikin jijiyoyin hannu a cikin retina.

Umarnin don amfani

An bada shawarar Meldonium da safe, saboda yana iya haifar da sakamako mai ban sha'awa. An saita kashi ɗaya akayi daban-daban dangane da alamun da kuma hanyar gudanarwa.

Lokacin ɗauka ta baki, kashi ɗaya shine 0.25-1 g, yawan sarrafawa da tsawon lokacin jiyya yana dogara ne da alamun.

0.5 ml na allurar bayani tare da maida hankali ne akan 500 MG / 5 ml ana gudanar da shi a cikin layi ɗaya na kwana 10.

Tare da gudanarwa na ciki, kashi shine 0.5-1 g 1 lokaci kowace rana, tsawon lokacin jiyya yana dogara da alamun.

An wajabta wa 'yan wasan motsa jiki don warkewar motsa jiki bisa ga tsarin musamman a hade tare da wasu hanyoyi. A bisa hukuma an yarda da shi azaman goro.

Yadda za a ɗauka tare da cututtuka?

1. Game da yaduwar illa, ana bada shawarar Meldonium a lokacin ɓarkewar 0.5 g sau ɗaya a rana don kwanaki 10, to a cikin nau'in encapsulated - 0.5 g kowace rana don kwanakin 14-21.
2. A cikin yanayin da ke fama da haɗarin kamuwa da cuta na ƙwaƙwalwar ƙwayar cuta, an tsara hanya ta jiyya ta tsawon kwanaki 14-21. Ana gudanar da allurar rigakafin intramuscularly a 0.5 g sau ɗaya a rana ko ana gudanar da shi a baki a 0.25 g (mita na sarrafawa ya dogara da tsananin yanayin yanayin mai haƙuri).
3. Rashin ciwo yana buƙatar hanya na magani tare da Meldonium na kwanaki 7-10. Sannan za a nuna mai haƙuri sau hudu na miyagun ƙwayoyi a lokacin rana, 0.5 g a ciki ko na lokaci-lokaci biyu.
4. Tare da barga angina pectoris, kwanakin 3-4 na farko ana wajabta su sau 0.25 g sau 3. Sannan ana shan su a baki sau biyu a sati a sati sau 0.25 g sau 3. Tsawan lokacin jiyya daga 4 zuwa 6 ne.
5. Tare da cardialgia, tare da dishormonal myocardial dystrophy, ana gudanar da miyagun ƙwayoyi a cikin hanyar jet sau ɗaya a rana, 0.5-1 g ko IM har zuwa sau 2 a rana, 0.5 g. Bayan kwanaki 10-14, ana ba da takardar maganin kapalin 0.25 MG da safe da maraice, ana ci gaba da jinya don wani kwanaki 12.
6. Tare da rashin daidaitaccen nau'in angina pectoris da infarction na myocardial, ana amfani da Meldonium a cikin jijiya ta hanyar jet na 0.5 g ko 1 g sau ɗaya a rana. Bayan haka, an wajabta shi a baki: 3-4 days - 0.25 g sau 2, sannan 2 days a mako 0.25 g sau 3 a rana.
7. Idan akwai cututtukan jijiyoyin jiki daga cikin asushin, dystrophy na retinal, Meldonium an wajabta shi a kan abin da ya faru na 10,05 g a cikin kwanaki 10.
8. A cikin rauni na zuciya, ana gudanar da maganin a cikin jijiya a cikin kullun a kashi na 0.5-1 g ko an maye gurbinsu da allurar intramuscular na 0.5 g har sau 2 a rana. Bayan kwanaki 10-14 na jiyya, an tura mai haƙuri zuwa cajin gg 0,5, wanda yakan dauki lokaci 1 da safe. Hanyar magani daga makonni hudu zuwa shida ne.

Yara yayin daukar ciki da lactation

Ba a tsara Meldonium ga mata masu juna biyu ba, tunda ba zai yiwu a tabbatar da lafiyar mahaifiyar da jaririn ba. Idan kuna buƙatar rubuta magani don mace mai shayarwa, to, a lokacin jiyya, an dakatar da shayarwa: ba a san ko kayan zai shiga cikin madara ba.

A cikin yara da matasa masu shekaru 18, ba a kafa ingantaccen tasiri da amincin lafiyar meldonium ba. Meldonium a cikin nau'i na capsules an contraindicated don amfani a cikin yara da matasa a ƙarƙashin shekara 18, a cikin nau'i na syrup a cikin yara a ƙarƙashin shekaru 12.

Umarni na musamman

Yi amfani tare da taka tsantsan a cikin cututtukan hanta da / ko kodan, musamman na dogon lokaci.

Shekaru da yawa na gogewa a cikin lura da matsanancin ƙwayar cuta na zuciya da rashin angina a cikin sassan aikin zuciya yana nuna cewa meldonium ba shine farkon layin farko na cututtukan jijiyoyin zuciya ba.

Gabaɗaya halayen

Meldonium abu ne wanda ke cikin magunguna da yawa. Amma wasu masana'antun samfuran magunguna suna kwantar da shi azaman magani mai zaman kanta, saboda yana da kayan haɓaka da antihypoxic, yana da tasiri ga tsarin jijiyoyi da jijiyoyin jini.

Meldonium magani ne na rukunin wakilai na rayuwa. Sunan kasa da kasa wanda ba na mallakarsa yayi daidai da abu mai aiki - Meldonium.

Tasiri akan jiki da magunguna

An yi amfani da Meldonium a cikin aikin zuciya da magani ta kaddarorin ta. Sau daya a cikin jiki, yana aiki da dama a lokaci daya:

• normalizes metabolism,
• Yana rage jinkirin narkewar nama, yana haɓaka saurin dawowa daga ciwon zuciya,
• yana inganta yanayin aiki na zuciya, yana kara juriya ga aikin jiki,
• yana rage yawan faruwar cutar angina,
• Yana kara karfin jini a cikin kwakwalwa,
• Yana inganta rigakafi
• sauƙaƙa alamun bayyanin hankali, ƙwayar cuta ta jiki,
• yana inganta aiki, juriya,
• yana kawar da alamun cirewa da suka taso kan asalin tsawan shan giya.

A miyagun ƙwayoyi yana da yawa tabbatattun kaddarorin. Amma ba da shawarar yin amfani da shi ba tare da neman likita ba. Daidai zabi sashi na magani kawai gwani na iya.

Tsarin saki, farashi

A cikin kasuwar magunguna, akwai nau'ikan sashi guda biyu:

• Capsules - suna da sifar silima tare da ƙarshen kewayon farin launi. An sanya su cikin sel 10. Yawan blister a cikin kunshin shine 3 ko 6.
• Magani - ana amfani dashi cikin ciki, intramuscularly ko parabulbarno. Sanya cikin ampoules 5 ml. Yawan abun cikin su kunshin 10.

Farashin Meldonium ya dogara da nau'in sakinsa, yanki na siyarwa da mai samarwa (Table 1).

Tebur 1 - Farashi a cikin kantin magunguna na yankuna daban daban

Farashin allunan Meldonium kusan iri ɗaya ne kuma sun tashi daga 156 zuwa 205 rubles. Don siyan magungunan, kuna buƙatar samar da kantin magani tare da takardar sayen magani na likita.

Abubuwa

Capsules ya ƙunshi 250 ko 500 MG na kayan aiki da irin waɗannan aka gyara:

• silloon silicon dioxide,
• dankalin turawa, sitaci
• magnesium stearate.

Hanyar aiwatar da maganin

An sanya kwaskwarimar kwanshin kwalliya daga:

• glycerin
• ruwa
• sodium lauryl sulfate,
• titanium dioxide
• gelatin.

Ampoule tare da maganin Meldonium ya ƙunshi 0.5 g na abu mai aiki. Additionalarin abubuwan da ke tattare da ƙwayar wannan nau'in ruwa kawai.

Manuniya da contraindications

Adadin Meldonium yana da faɗi sosai. An tsara shi don cututtuka na tsarin na numfashi da idanu, cututtukan zuciya da cuta na jijiyoyin jiki. Ana iya ba da wannan magani ga:

• bugun zuciya
• angina zakariya,
• cututtukan zuciya wanda ya haifar da lalacewa daga raunin zuciya,
• karancin aiki
• babban tashin hankali na zagayarwar jini a cikin cikin retina,
• gajiyawar jiki,
• na kullum zuciya,
• zub da jini a cikin jijiyoyin jikin kwayar halitta daban-daban,
• ischemic bugun jini
• cututtukan retinal, waɗanda suke rikice-rikice na ciwon sukari mellitus, hauhawar jini,
• bambancin encephalopathy,
• na kullum
• gaban jini clots a cikin tsakiyar tasoshin na retina,
• maido da cutar barasa,
• asma.

Hakanan ana amfani da Meldonium bayan tiyata - don hanzarta aiwatar da sabuntawa na gaba ɗaya da farfadowar nama.

Kamar kowane magunguna, ƙwayar tana da contraindications. Abubuwan da ke hana yiwuwar amfani da shi sun hada da:

• babban matsin lamba,
• rashin haƙuri da aka gyara daga cikin miyagun ƙwayoyi,
• shekarun yara (kafin shekarun 18, shan maganin ba da shawarar ba).

An tsara wa marasa lafiya da cututtukan hanta da kodan da miyagun ƙwayoyi tare da taka tsantsan. Amfani da Meldonium a gaban contraindications haramun ne: wannan yana barazanar inganta rayuwar jin daɗinsa, haɓaka rikice-rikice game da asalin cutar.

Yaya za a kirkiri sashi na allunan da kuma mafita?

Yawan magungunan da aka dauka ya dogara da halaye na mutum na mai haƙuri da yanayin cutar:

Shawarar da aka bada shawarar Meldonium a cikin cututtukan cire barasa shine 500 MG. Ana ɗaukar ta a baki ko a allurar a cikin jijiya. A cikin yanayin farko, ana amfani da miyagun ƙwayoyi har zuwa sau 4 a rana, a cikin na biyu - ba fiye da sau 2. Tsawon lokacin amfani da miyagun ƙwayoyi shine mako 1.5.

Tare da ƙoshin jiki, kamar yadda bayan tiyata, ya zama dole a ɗauki Meldonium sau 4 a rana. Singleari ɗaya shine 0.25 g amma zaka iya amfani da bayani. An saka shi cikin jijiya ko gluteus muscle a cikin adadin 0-1-1 g.

Mitar kulawa da miyagun ƙwayoyi a cikin jini sau ɗaya a rana. Ya isa a allurar da ƙwayoyi sau 2 a rana a cikin tsoka. Ana bin irin wannan tsarin kulawa don makonni 1.5-2. Idan an nuna, ana maimaita maganin bayan kwanaki 14-21.

Marasa lafiya tare da raunin jijiyoyin wuya a cikin kwakwalwa suna amfani da miyagun ƙwayoyi bisa ga wannan makirci: kwanaki 10, maganin maganin a cikin adadin 500 MG kowace rana ana allurar cikin jijiya, bayan wannan lokacin suna ɗaukar capsules na wani makonni 2-3. Matsakaicin da kuma yawan shan miyagun ƙwayoyi ba ya canzawa.

A kan asalin jiyya tare da Meldonium, wani ɗan ƙaramin sakamako mai ban sha'awa na iya faruwa. Sabili da haka, yana da kyau a yi amfani da shi da safe. Capsules sun bugu kafin abinci, tare da ruwa mai yawa.

Ga cututtukan zuciya

Ba a haɗa Meldonium cikin rukunin ƙwayoyi na zaɓaɓɓen magani don magance cututtukan zuciya ba, cututtukan jijiyoyin jiki: a matsayin magani mai zaman kanta ba shi da tasiri. An wajabta amfani dashi a matsayin wani ɓangare na hadadden farjin rashin lafiyar angina pectoris, infarction na zuciya, ciwon zuciya da gazawar zuciya.

Marasa lafiya tare da tsayayyen angina pectoris suna ɗaukar 250 mg na meldonium sau uku a rana don kwanaki 3-4. A nan gaba, ana amfani da miyagun ƙwayoyi bisa ga makirci iri ɗaya, amma sau biyu a mako. Aikin magani shine watanni 1-1.5.

Don lura da cututtukan zuciya, wanda ya bayyana saboda raunin zuciya mai ƙyama, ana ba da shawarar gabatar da Meldonium a cikin jijiya ko tsoka a ƙaddara na 500 MG. A farkon lamari, ana amfani da abu sau ɗaya a rana, a na biyu - sau biyu a rana. Farjin yana wuce sati 1.5-2. Bayan wannan lokacin, ɗauki kwayoyin. Maganinsu na yau da kullun shine 500 MG (Allunan 2 suna dauke da 250 mg na abu mai aiki). An kasu kashi biyu. Ana ci gaba da jiyya don wasu kwanaki 12.

Tare da infarction na myocardial, angina mai rashin ƙarfi a cikin kwanakin farko na maganin, ana amfani da Meldonium cikin ciki: ana gudanar da maganin 0.5-1 g na bayani. Sauran kwanaki 3-4 masu zuwa, ɗauki capsules: 250 MG sau biyu a rana. Bayan wannan lokacin, yawan shan miyagun ƙwayoyi yana ƙaruwa sau 3, amma ana amfani dashi kowane kwanaki 3-4.

Wadanda aka gano tare da raunin zuciya na zuciya ana lasafta su ta hanyar gudanarwar ciki ko gudanarwar maganin Meldonium na kwanaki 10-14. Yawan sashi da yawan amfaninsa shine 0.5-1 g da sau 1 ko 2 a rana, bi da bi. Bayan makonni 2, an wajabta maganin kawa a daidai sashi. Jimlar magani shine watanni 1-1.5.

Meldonium yana haɓaka samar da myocardium, ƙwayar tsoka tare da jini da oxygen, yana haɓaka tafiyar matakai na rayuwa, yana ƙara ƙarfin gwiwa. Sabili da haka, ana amfani dashi ba kawai a magani ba, har ma a wasanni.

Ya kamata a fahimci cewa Meldonium baya tasiri kai tsaye ga ƙaruwar 'yan wasa, yana dakatar da alamun wuce gona da iri, yana ƙara ƙarfin halin jiki, wanda ke ba da damar haɓaka inganci da tsawon lokacin horo.

Hanyar aikin miyagun ƙwayoyi ya dogara ne da dakatar da tasirin carnitine, wanda zai ba ku damar canza jiki daga ɗaukar mai zuwa fifikon glucose don makamashi.

Shawarwarin maganin da aka ba da shawarar yayin motsa jiki shine 0.5-1 g. Ya kamata a sha cokali biyu sau biyu a rana don rabin sa'a kafin horo. Tsawon lokacin shan miyagun ƙwayoyi ya kasance ne daga makonni 2-3 zuwa watanni 3.

Na dogon lokaci, 'yan wasa a duk faɗin duniya sun ɗauki Meldonium don ƙara haƙuri da motsa jiki. Amma a yau an hana shi amfani da shi a cikin wasanni masu sana'a. Tun daga shekara ta 2016, an bashi karbuwa a hukumance kamar yadda ya zama mai ci. Don amfani da ita yana barazanar ficewa daga shekaru 4.

Don asarar nauyi

A yau, mutum zai iya samun ra'ayin sau da yawa cewa Meldonium yana taimakawa rage nauyi. Shin haka ne? Gaskiya yana shiga cikin tsari na kwayar halitta, kuma daga nan gaba daya yanayin jikin mutum, godiya ga kaddarorin antioxidant, detoxifies.

Cholesterol mai kyau da mara kyau

Wadannan matakai na iya rage matsayin mummunar cholesterol a cikin jiki, amma har yanzu yana da mahimmanci a fahimci cewa a matsayin hanyar zaman kanta na ma'amala da karin fam, ba shi da tasiri. Don cimma tasirin da ake so, ya zama dole a haɗa liyafar ta tare da aikin motsa jiki: motsa jiki, jogging, iska, motsa jiki. Wannan zai inganta metabolism da amsawar jiki ga damuwa, kuma zai haifar da asarar nauyi.

Wajibi ne a ɗauki Meldonium a cikin capsules don asarar nauyi kafin motsa jiki a cikin kashi na 0-1-1 g .. Yana da kyau a sha maganin da safe: shan shi da yamma zai iya tayar da rashin bacci.

Meldonium, umarnin don amfani (Hanyar da sashi)

Kafurai Meldonium-MIK an dauki shi a baki kuma dangane da yiwuwar sakamako mai ban sha'awa, ana bada shawara a sha su da safe. Ana zaɓi kashi da mita na gudanarwa daban-daban.

Tare da cututtukan zuciya - 500 mg-1000 MG kowace rana. Jiyya yana zuwa makwanni shida.

A cikin yanayin hatsarin cerebrovascular - 500 mg sau ɗaya a rana, a cikin hanya na makonni 4-6.

A karban ciwo - 500 MG sau 4 a rana.

Tare da nauyin jiki - 250 mg sau 4 a rana, hanya na kwanaki 14.

Yawan damuwa

A miyagun ƙwayoyi ne dan kadan mai guba da overdose lokuta ba su faruwa ko suna da wuya sosai. Ci gaba mai yiwuwa ne a tsari tashin hankali, samarin, ciwon kai, tsananin farin ciki da rauni gaba daya. Ana gudanar da aikin tiyata.

Haɗa kai

Yana inganta aikin antihypertensive, magungunan antianginal, glycosides na zuciya.

Wataƙila haɗuwa tare da magungunan antianginal, maganin anticoagulants, magungunan antiarrhythmic da diuretics.

Tare da amfani da lokaci daya Nitroglycerin, alfa adrenergic blockers, NifedipineAkwai yiwuwar vasodilators na gefe yana yiwuwa samarin da jijiyoyin jini.

Kada kayi amfani lokaci guda tare da wasu magungunan da ke dauke da meldonium.

Ra'ayoyi game da Meldonia

Wa'adin wannan magani a cikin hadaddun jiyya na cututtukan zuciya ya rage da kashi 55.6% na yawan cututtukan angina pectoris da bukatun yau da kullun don nitroglycerin ta hanyar 55,1%. Da muhimmanci inganta ƙanƙancewa myocardium babu wani tasiri a cikin bugun zuciya, yana iyakance hawa da sauka BOKA. Magungunan ba shi da guba kuma baya haifar da mummunan illa.

Yin hukunci da sake dubawar marasa lafiya, an wajabta wannan maganin Ciwon zuciya na Ischemic a hade tare da magungunan antianginal da antihypertensive. Yana da mahimmanci cewa an wajabta magunguna ga marasa lafiya na tsofaffi kuma sun jure shi da kyau.

• «... Na ƙara allunan Meldonium don angina pectoris, zuwa wasu allunan. Ganin cigaba bayan makonni 3»,
• «... Na ɗauki sau 2 a rana bayan bugun ƙwayar cuta a cikin capsules. Sha wata daya da rabi - magana ta inganta, vigor ya bayyana»,
• «... Ina daukar darussan sau uku a shekara. Zan iya rarrabe shi da mahimmanci ga kowa da kowa. Ina da angina pectoris da hauhawar karfin jini»,
• «... Yaron ya cika shekara guda, ya gaji sosai. A kan shawarar mai ilimin kwantar da hankali, na dauki Meldonium sau biyu a rana. Ina sha kawai mako guda da jin daɗin riga»,
• «... Likita ne ya ba ni shawarar (sanadin “mai gajiya”). Tsarin allura mai tsada. Madalla da magani, da sauri dawo da ƙarfi»,
• «... Na lura cewa ɗaukar Meldonium dan ƙara yawan ci, har ma da warke kaɗan»,
• «... Bayan kwana 7 na shan wannan magani, sai kaina ya bugu».

Analogs na miyagun ƙwayoyi Meldonium

Tsarin yana tantance analogues:

1. Vasomag.
2. Meldonium bushewa.
3. Idrinol
4. Meldonium Organics (Binergia, Eskom).
5. Angiocardyl.
6. 3- (2,2,2-Trimethylhydrazinium) daskararre mai narkewa.
7. Cardionate
8. Midolat.
9. Medatern.
10. Tafiya.
11. Mildronate

Don lura da nauyin jiki da na tunani, dawo da jiki, ana analo analogues ta aiki:

1. Lamivit.
2. Eleutherococcus cirewa.
3. Harshen Cigapan.
4. Yantavit.
5. Falkamine.
6. Ascovite.
7. Galavit.
8. Centrum.
9. Cardionate
10. Barkono
11. Hepargin.
12. Triovit.
13. Idrinol
14. Eltacin.
15. Corilip.
16. Ribonosin
17. Vazoton (L-arginine).
18. Vasomag.
19. Selmevit.
20. Pikovit forte.
21. Berocca da.
22. Pantogam.
23. Heptolexin.
24. Mildronate
25. Abincin abinci.
26. Litattafan mahaifa
27. Valeocor Q10.
28. Pikovit.
29. Coudewita.
30. Carnitine.
31. Dibikor.
32. Trekrezan.
33. Abinci.
34. Elkar.
35. Riboxin
36. Vitamax
37. Harshen Pantocalcin.
38. Antioxidants tare da aidin.
39. Cytoflavin.
40. Harshen Cropanol.
41. Neoton.
42. Nagipol.
43. Bashin
44. Jeriton.
45. Oligovit.
46. Duovit.
47. Encephabol.
48. Kudesan.
49. Metaprot.
50. Withara tare da baƙin ƙarfe.
51. Asvitol.
52. Inosine.
53. Vitrum ƙari.
54. Leriton kadari.
55. Saukad da Beresh ƙari.
56. Coenzyme compositum.

A lokacin daukar ciki

Ikon Meldonium ya shiga cikin mahaifa da nono, ba a fahimci tasirinsa ga tayin da haɓakar yarinyar. Saboda haka, bisa ga umarnin, ba a ba da shawarar amfani da shi ga mata masu juna biyu da uwaye masu shayarwa.

Duk da iyakancewar da aka bayyana a cikin bayanin, yau Meldonium yana cikin wasu halaye waɗanda ake amfani dasu don kula da mata masu juna biyu. Alamu na iya zama:

Karancin rashin haihuwa a jiki. Wannan ilimin saniyar ya samo asali ne sakamakon take hakkin zubar jini zuwa ga mahaifa, daga nan ne tayi. Wannan yanayin mai haɗari na iya haifar da mutuwar yaron. Wannan ilimin likita yana da wuyar magancewa, sabili da haka, a matsayin matakan gaggawa, Meldonium wani lokaci ana wajabta shi, wanda zai iya rage yawan oxygen na sel jikin mahaifiya da tayin, hana haɓakar hypoxia, da hana maye.

Take hakki a cikin aikin kwadago, musamman tsayi da yawa, saboda abin da mahaifiyar ke jin nauyinta, da kuma yaron yana fuskantar rashin nauyi. Waɗannan yanayin suna iya haifar da mummunan sakamako, har ma da mutuwa.

Meldonium yana ba ku damar kwantar da aikin jijiyoyin macce da ke cikin aiki da tayin, haka kuma don daidaita tsarin haihuwa. Yana da kyau a faɗi cewa ƙwayar ba ta samar da ƙarin oxygen ga sel ba, amma yana rage ƙarin da ake buƙata.

Nazarin likitoci game da meldonium

Magungunan "Meldonium", wanda kwayar halitta ta shiga cikin abubuwan da ke tattare da kwayar makamashi (Adenositol triphosphate), a hade tare da bitamin B, ya dace da magungunan anti-steroidal anti-mai kumburi a cikin maganin dorsopathies na asalin asali.

Halin motsin rai na marasa lafiya ga gaskiyar cewa an wajabta su "doping" (1 lokaci).

Yana aiki idan kun san yadda kuma dalilin dalilin nada shi. Gaskiyar cewa miyagun ƙwayoyi suna da matukar rikitarwa kuma suna iya haifar da rashin amfani da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwayoyi to bai kamata a manta da su ba, saboda lokacin da muke rubuta shi, yawanci muna ba da maganin warkarwa.

Ba za a iya amfani dashi a cikin maganin monotherapy ba, yawancin marasa lafiya suna jin daɗinsu, amma wasu ba sa jin tasirin.

Magungunan, a zahiri, kamar mutane da yawa a zamanin yau, suna da kyakkyawan nuna haƙuri, babu rashin lafiyan halayen, ana iya haƙuri da shi ta hanyar marasa lafiya ko da a haɗuwa tare da babban maganin kwantar da hankali, duk da haka, duk da tabbacin tushe, ko ta yaya ba ku jin shi tare da kwaya wanda zai warke mai yiwuwa, ya kusanci kyawawan abubuwan da ake amfani da su na kwayoyin halitta, bitamin.

Mai araha, gwada-lokaci, ingantaccen magani

Don samun sakamako da ake so, kuna buƙatar ɗaukar shi kamar yadda likita ya umarta, a cikin isasshen kashi da madaidaiciyar hanya na tsawonwa. Idan sakamakon ba shi da gamsarwa - mafi yawan lokuta ba batun maganin ba ne, amma fassarar fassarar cutar ko isasshen magunguna.

Meldonium shiri ne mai kyau wanda ya dace da tsarin kula da cututtukan kwakwalwa da cututtukan zuciya. Magungunan yana da mahimmanci musamman lokacin da ake haɗuwa da waɗannan cututtukan, wanda galibi ana samun shi a cikin masu haƙuri da ke da shekaru. An yi bayanin ingancin "Meldonium" ta gaskiyar cewa yana haɓaka haɓaka tasoshin jini na microvasculature kuma yana tsara jigilar ATP da oxygen, wanda ya zama dole don isasshen abincin abinci na sel jijiya da ƙwayoyin myocardial. Na kuma yi nasarar amfani da wannan magani don hadaddun magani na VVD, polyneuropathies, sakamakon raunin kai da sauran cututtukan cututtukan zuciya. Na farko, Ina sanya magani a cikin nau'i mai allurar 5.0 - 10.0 a cikin wani rafi N 10, sannan a cikin capsules na 250 MG 2 sau a rana don wata. Bayan hanyar maganin, marasa lafiya sun lura da raguwa a cikin damuwa, rashin jin daɗi a cikin zuciya, raguwar hauhawar jini, raguwa a cikin hannu da ƙafafu, haɓaka iya aiki, da haɓaka karbuwa ga damuwa ta jiki da ta hankali.

Wani lokaci a cikin marasa lafiya da ke tare da normosthenic ko asthenic physique, waɗanda da farko suna da ƙarancin jini, ana lura da raguwa wanda ba a so.Wasu lokuta, marasa lafiya na rukuni guda game da asalin maganin suna da alamun bayyanar cututtuka, wanda, bisa ka'ida, an gyara su tare da taimakon gastroprotectors.

Magungunan yana da sakamako masu illa da contraindications. Onlyauki kawai kamar yadda likitanka ya umurce ku.

An yarda da maganin sosai. Ina rubutowa ga marasa lafiya masu dauke da cututtukan zuciya, idan ba a ba su magani ba. Marasa lafiya a kowane zamani suna haƙuri da kyau. Ina son mai laushi da dawwama mai tasiri. Kawai kuna buƙatar bin umarnin kuma ɗauka akalla wata guda. Kuna iya fara iv drip, sannan a cikin capsules.

Ba'a haɗa magunguna tare da ingantaccen aikin asibiti ba cikin kowane jagorar magani na kasashen waje don komai. Placeaƙwalwar motsa jiki ta ƙarshe, yayi ƙoƙari ya ɗauki nauyin kansu yayin ƙoƙarin jiki, bai lura da tasirin ba.

Kada ku ɓata kuɗin ku a banza.

Zai fi kyau bi tsarin da ya dace, kwanciyar hankali da motsa jiki.

Ba na son gaskiyar cewa wasu likitocin da marasa lafiya suna tsinkayar motsa jiki a matsayin magani.

Meldonium ba a nufin warkar da cututtuka. Dalilin shaidar sa a zuciya ta gaba daya bata nan. Ina zargin cewa dangane da wasu fannoni ma.

Idan kuna buƙatar vigor na ɗan lokaci da haɓaka aiki ta hanyar inganta jikin - to, watakila, meldonium zaiyi. 'Yan wasa sun san wannan. Amma wannan baya nufin cewa meldonium “yana warkarwa” wani abu.

Kwanan nan, ya sau da yawa ya fara ba da magani tare da Meldonium. Musamman, na yi ƙoƙarin bayar da shawarar ɗaukar wannan magani ga mai haƙuri tare da nau'ikan bulbar cutar scyorosis na amyotrophic (yawanci cuta ce mai saurin ci gaba) kuma, ga mamakina mai daɗi, mai haƙuri ya lura da tasirin magani. Bugu da ƙari, ƙwayar tana da farashi mai araha.

Wani magani mai araha, marasa lafiya sun lura da sakamako mai kyau a cikin yanayi daban-daban. (A cikin yanayin asthenic da yanayi masu damuwa). An lura da hauhawar ƙarfin hali da ɗan ci gaba cikin yanayi. Yana ƙaruwa da juriya tare da rikice-rikice na zuciya.

Ana buƙatar jarraba na farko na likita na mai ilimin hanyoyin kwantar da hankali da kula da shigarwar.

Sakamakon mai yiwuwa

Abubuwan sakamako masu illa a yayin amfani yawanci basa faruwa. Amma wani lokacin ana iya samun rikice-rikice akan sashin zuciya da jijiyoyi, fata da narkewa. Sun bayyana a cikin irin waɗannan alamun:

• samarin
• bambance-bambance a cikin karfin jini,
• m jihar
• bayyananniyar bayyani,
• redness, itching da kumburi na fata.

Idan amfani da Meldonium ba zai yiwu ba, an maye gurbin shi da kwayoyi waɗanda ke da nau'ikan tsari ko irin tsarin aikin.

Tsarin tsari

A cikin kasuwar magunguna, akwai irin wannan tsarin analogues na Meldonium:

1. Medatern. An gabatar da wannan magani a cikin kwatancin kwalliya. Ana amfani dashi don rage ƙarfin aiki, ƙwaƙwalwa da damuwa ta jiki, cututtukan zuciya da jijiyoyin jini, lalata jini kewaya cikin kwakwalwa. Za'a iya siyan capsules mai nauyin 250 na kayan aiki mai aiki don 300-350 rubles.
2. Mildronate Magunguna wanda aka kirkira don inganta metabolism, samar da makamashi na kyallen takarda. Akwai shi a cikin capsules kuma a cikin hanyar mafita. Yana da alamomi iri ɗaya da iyakance don amfani dashi kamar Meldonium. Matsakaicin farashin maganin: 600-700 rubles. - 60 capsules tare da 500 MG na kayan aiki, kimanin 300 rubles. - capsules 40 dauke da 250 MG na Meldonium. Farashin mafita shine 355-370 rubles.

Akwai wasu hanyoyin analogues na Meldonium - Vasomag, Midolat. Ka'idojin aiki, alamomi da hani ɗaya ne a gare su. Magungunan sun banbanta ne kawai a ƙasar asalin da farashin.

Shirye-shirye tare da irin wannan manufa ta aiki

Jerin analogues na tasirin da aka bayar ya hada da:

Preductal maganin rigakafin ischemic ne, magani ne na antianginal. Babban abincinta shine trimetazidine dihydrochloride. Akwai shi a cikin allunan da ke ɗauke da 20 ko 35 MG na kayan aiki masu aiki.

Ana amfani dashi a cikin aikin zuciya, cututtukan ophthalmic da al'adun otolaryngological: don angina pectoris, rikicewar chorioretinal da rikicewar vestibulo-cochlear na yanayin ischemic. Ba'a ba da shawarar ga yara, mata masu juna biyu da uwaye masu shayarwa ba. Matsakaicin farashin magani shine 1700 rubles.

Riboxin magani ne wanda ba mai steroidal ba tare da abubuwan haɓaka, antiarrhythmic da kaddarorin antihypoxic. Ana amfani dashi don rikicewar bugun zuciya, atherosclerosis, cututtukan zuciya da jijiyoyin jini, giya mai guba, cututtukan ciki da ciki.

Magungunan yana haɓaka metabolism, inganta samar da kyallen takarda tare da jini da oxygen, yana ƙara ƙarfin jiki yayin aiki mai ƙarfi na jiki. Kudin samfurin ya kasance daga 20 rubles. (ya dogara da nau'in sakinsa).

Mexidol - ana samun su ta hanyar mafita, allunan, kazalika da haƙoran hakori. An tsara shi ga marasa lafiya da cutar ta VVD, atherosclerosis, hatsarin cerebrovascular, cututtukan hakori (manna) da cututtukan da hypoxia na nama ke faruwa. Kuna iya siyan haƙori na 200 rubles. Farashin Allunan da bayani daga 256 kuma daga 506 rubles, bi da bi.

Kafin maye gurbin Meldonium tare da tsarin analogues na tsari ko kwayoyi tare da irin wannan ka'idar aiki, ya zama tilas a nemi likita.

Shaidar marasa lafiya game da meldonia

Kiwan lafiya ga duka! Ina so in saka "kaso 5" na "Meldonius"! A karo na farko da na sha hanyar kwana 30 na 1000 a cikin shekarar 2017! Sakamakon ya kasance mai ban tsoro! Ganin cewa babu wani karfin da zai iya tashi daga gado, tuni a rana ta uku na tashi kan kasuwanci, kamar wani hadaddiyar iska! Sannan na yi shekara 60, wata shida daga baya na ci gaba da karatun, amma 500 a rana. kuma ban ji daɗin yawa ba! Duk da haka, Ina bayar da shawarar ga waɗanda ke fama da rauni da depresnyakom! Yanzu akwai Rasha da aka yi, riga aka saya kuma aka fara ɗauka! Lokacin bazara, rashi na bitamin, lalaci da sauran sakamako masu illa da jijiyoyin jiki! Boom yaqi? Boom!

Ina aiki da dare, ɗaukar Meldonium wasu lokuta 25-30 capsules 250 kowace rana, yana taimakawa kada barci yayi barci. Duk da yake babu wani sakamako masu illa, Ina ɗaukar wata guda.

Ya wuce aikin injections guda 10 cikin hanzari. Akwai babban abin mamaki a fannin zuciya. Matsewa, matsi mai zafi, gajeriyar numfashi yayin ƙoƙarin jiki, rauni da safe. Bayan wucewa da ECG, likita ya ba da allurai na Meldonium. Haƙuri yana da kyau, babu wasu sakamako masu illa. Nan da nan bayan na sami allura, sai na ji damar da zan ɗauka cike da zurfi. Maimaita ECG ya nuna babban ci gaba. A cikin aikin, bayan shekara daya, kan shawarar likita, ta maimaita karatun. Da kyau.

Mutanen da ke magana game da rashin ingancin maganin makaryata ne. Ko kuma kar a dame ku don karanta umarnin. Na sayi capsules 40 a sashi na 250 MG. Ina shan cokula 2 da safe. Sashi don ɗan wasa mai son wasan kwaikwayo shine kawai nauyin 0,5 a rana. Very lura ƙara ƙarfin hali. Kafin nan, ya kasance da wahala a gare ni in lura da sana'ata da kuma motsa jiki a lokaci guda. Yanzu zan iya yin kasuwanci da wasanni kowace rana. Tuni ba ciwo da rage tsokoki. Bayan aiki, zan iya gudu da hawa keke don kilomita 8-12. Ko kuma je don horo mai ƙarfi. Abin da kuma na lura - filin na numfashi da kuma samar da iskar oxygen tare da jini tabbas ya inganta. Inda ba ni da numfashi, tuni na ɓace. Inda yawanci ba zan iya gudu daga rashin ƙarfi ba, yanzu ina gudu Wasanni ya fara kawo farin ciki, kuma ba ya zama gari kafin ko bayan duk ayyukan da ake amfani da kuzari. Sashi 0.5 g kowace rana. Kuma babu fiye da 1 gram na prof. 'yan wasa! In ba haka ba, ba za a sami sakamako ba.

Na yi karatu shekaru biyu da suka gabata kuma na yi fama da matsanancin rashin kwanciyar hankali da rauni. Neman shawara da likita, na tambaye shi game da wannan maganin kuma ko zai taimaka mini a cikin yaki da danniya da gajiya. Ya ba ni amsa mai kyau kuma ya ce wannan kayan aiki ne mai ƙarfi don girgiza jikin ku. Ina godiya ga wannan likita. Damuwa kawai ta ragu, kuma motsin zuciyar kirki ya zo don maye gurbin ta, da kuma sha'awar yin aiki da motsawa! Tabbas, Meldonium yana da tasiri kuma babu wata hanyar da za a bi don magance wannan maganin tare da yawan shakku. Hakanan yana da kyau a faɗi cewa kuna buƙatar bin umarnin don amfani da Meldonium. Rashin wuce gona da iri zai kai ka zuwa mummunan yanayin. Don haka, idan kai mai sauƙi ne mai ƙwaƙƙwaran aiki kuma ba ƙwararren ɗan wasa ba, kuma kun sha wahala daga gajiya da damuwa, to Meldoniy kawai zai sa ku zama mafi kyau!

Ina asibiti na zuciya da jijiyoyin jini. Rushewar bugun zuciya, fibrillation a gaban thyrotoxicosis. Akai-akai. A wannan lokacin, an sanya kwafin chloride tare da meldonium. A rana ta biyu sai na ji an inganta. Bayan kwanaki 10 tare da sarrafawa ECG akwai ci gaba. Ina bayar da shawarar shi!

Na yi rashin haƙuri ga ƙwayoyi da yawa da kuma matsanancin matakin hauhawar jini. Lokaci-lokaci Ina gwada sababbin magunguna wa kaina. Na gwada Meldonium A rana ta biyu, arrhythmia, tachycardia, wahayi mai haske ya bayyana. Matsin lamba ya ragu zuwa 160. Ina da wannan yanayin bayan shan diuretics. "Meldonium" a fili abin farin ciki ne. Yayin da nake ɗaukar sa, na yi barci sosai. Don haka wannan a bayyane yake ba mai kare ba ne, amma bai dace da ni ba. Fuskanta kawai mako daya. Zan sake gwadawa a cikin karamin kashi kuma kawai da safe.

Ina shan "Mildronate" daga osteochondrosis na kashin baya, yana taimakawa, amma kuna buƙatar sha gwargwadon umarnin don akalla wata daya, ƙishi da rauni sun tafi, kuma kaina ya bayyana. Na sanya allura guda 10 a cikin jijiya, sannan kwayoyin. Yana da daraja a gwada.

Na tsunduma cikin nauyi kamar "mai son", cikin nishadi. Wani nau'in bayyanar nan take bai kamata a tsammaci ba, amma alamomi masu ƙarfi sun girma da kyau, murmurewa bayan horo yana da sauri, yanayin jiki ya inganta. Ni dan shekara 43 ne.

Kyawawan magani! Ya tayar da ni! Increasedarfi ya ƙaru, yanayi ya inganta! A bara na kammala hanya a cikin bazara, yanzu na sake maimaitawa!

Kuma a wannan shekarar na gano menene Meldonius, lokacin da suka fara magana game da 'yan wasa. Ban san abin da aka sayar a cikin kantin magani ba. Na gano, na gwada. Wannan shine cetona. Gaskiyar ita ce, a cikin 'yan shekarun nan hannayena sun lalace. Lokacin da mahaifa musamman, to, rauni a cikin jiki. Ina jin kamar wata tsohuwa. yana dan shekara 43. Don haka "Cardionate" (meldonium) yanzu ya cece ni. Yana ba da ƙarfi, ina rayuwa yanzu. Zan sha marufin. Ina jin sauki sosai. kuma sake har sai tashin hankali na gaba (daga rashin bacci da gajiya mai yawan gaske). Na yi tunanin cewa yana ba da ƙarfi ne kawai, sai dai itace cewa sores ya wuce cikin sauri. Kuma likitoci ne kawai sukeyi a jikinsa. Kuma mutane da yawa na iya yi. Contraindications, kamar, kawai arrhythmia da cututtuka na kodan da hanta. A waccan shekarar, yayin da na je wurin neuropathologist don ganawa tare da karin magana game da cutar mahaifa, na cire wannan matsalar tare da meldonium kuma na ba shi labarin. Wataƙila zai shawarci wasu.

Meldonium yana da tasirin rikicewa a jikin mai wasan. Hisarfin da ake zarginsa da shi na inganta madawwamin lafiyar mutane bashi da tabbataccen hujja. A cikin gwaji na asibiti guda ɗaya kawai da aka gudanar akan karamin rukuni na tsofaffi masu shekaru 60 tare da angina pectoris, meldonium ya nuna cigaba a cikin haƙuri.

A koyaushe ina aiki tuƙuru, na yi tunani ba zan taɓa gajiya ba, amma yara 3 da wani wanda ya gama karatun digiri, a fili, ya yi dabarar. Ta ji wani irin rauni a cikin zuciya, ECG ta bayyana katangar abun. Ya zama ko ta yaya ban tsoro a 37. Likita ya ba da umarnin meldonium, yana inganta ingantaccen kofi fiye da kofi, yana sake cike da kuzari, abin takaici hanya za ta ƙare nan da nan. Magunguna don supermen, Tabbas na taimaka fita.

Ina da bugun jini guda 2, na hadiye allunan na kankara a cikin fakitoci har sai da na lura - wannan duk maganar banza ce. Kwayoyin marasa amfani.

Muna gina gida tare da dan uwana, galibi akan kanmu. Ya fara jin rashin lafiya, ya je wurin likita, kuma ya kamu da gajiya mai rauni da gajiya ta jiki. Ya bada shawarar kwanciya har sati daya a asibiti. Sun yi mini allura da magani "Meldonium." Kyakkyawan magani, ƙarfi yana dawowa a zahiri gaban idanunmu. Bayan wasu 'yan kwanaki ina cikin koshin lafiya da karfin jiki, amma duk da haka an shawo kaina na sha magani har karshensa. A cikin kwanaki biyu na farko, an ba da gaskiyar magana tare da glucose, amma "Meldonium" ya taimaka min sosai. Yanzu kuma na sayi magungunan - Zan ɗauka yayin da akwai manyan kuɗaɗe.

Na san da amfani da Meldonium na dogon lokaci. Tun da shigo da analog mai tsada yana da tsada sosai, kuma magani yana taimaka mini sosai, Dole ne in sami wanda zai maye gurbinsa. Ina musamman son in lura da tasirin meldonium a fagen inganta aikin - yana aiki daidai gare ni! Kawai tabbata a fara tattaunawa da masanin ilimin kimiya na zuciya.

Short Short

Meldonium abu ne mai karfi na shahararren magungunan Mildronate (za a yi rubutu game da shi daban), wanda kuma magani ne mai zaman kansa wanda kamfanin masana'antar harhada magunguna na gida ya samar. Meldonium yana ƙaddamar da matakin salula a matsayin caca na martaba mai mahimmanci a cikin magunguna, hulɗa da canji wanda ke shafar metabolism kuma yana ba da damar yin amfani da wannan magani duka a cikin yanayin "solo" kuma a matsayin wani ɓangare na haɗin jiyya a cikin waɗannan ga alama ga cikakkun wuraren da ba a haɗa su ba, kamar yadda ake kula da cututtukan zuciya da jijiyoyin jiki, lura da alamun cirewa da gyara yanayin asthenic. Hanyar aiwatar da wannan maganin ba zai yiwu ba a fahimta ta ta hanyar wani mutum da ba a san shi ba a cikin asirin kimiyyar halittu: meldonium yana hana mahaɗan enzyme gamma-butyrobetaine hydroxygenase da ke haɗuwa da carnitine, sakamakon haifar da haɓakar gamma-butyrobetaine, wanda ke da kaddarorin vasodilating. Amma wannan ba duk fa'idodin meldonium ba: yana hana motsi na tsawon sarkar acid ta hanyar membrane, yana magance kasancewar da haɓakawa a cikin sel masu aiki na siffofin kitse na unoxidized, waɗanda sune asalin Acyl coenzyme A da acyl carnitine. Kuma idan har yanzu ba a bayyane yake ga yawancin masu karatu menene wannan ma'anar ba, to ya kamata ku yi haƙuri ku ci gaba da karatu. Ofaya daga cikin mahimman tasirin asibiti na meldonium shine gyaran daidaitaccen damuwa tsakanin ƙaddamar da oxygen zuwa sel da yawan amfani a cikin mummunan yanayin ischemia (Encyclopedia Mai Girma Soviet yana ba da cikakkiyar ingantacciyar ma'anar fahimta game da wannan yanayin cututtukan cuta - rashin lafiyar gida).

Magungunan yana hana cin zarafin jigilar jigilar ƙananan ƙwayoyin sel - ATP, yayin da a lokaci guda ke kunna anaerobic glycolysis. Tare da ischemia na ƙwayar zuciya, meldonium yana jinkirta samuwar yankin necrosis, yana gajarta lokacin murmurewa. Tare da rashin isasshen aiki na zuciya, yana kara yawan aiki da karfin zuciya, yana bawa marassa ikon juriya da kokarin motsa jiki, da kuma rage yawan angina pectoris. A matakin wayewar kai, meldonium yana kara karfin aiki, sautunan sama da tsarin juyayi na tsakiya, yana kunna garkuwar jiki, da kuma sauqaqa damuwar jiki da ta kwakwalwa.

Meldonium yana samuwa a cikin nau'i na capsules da mafita don allura. Ana ɗaukar nau'in sashi na abinci kafin abinci.Matsakaici, mita da tsawon lokacin gudanarwa ana ƙaddara ta takamaiman cuta kuma yana iya bambanta cikin yanayi mai nisa: alal misali, tsawon lokaci na meldonium a cikin buguwa ta zuciya, kwanciyar hankali angina pectoris ko haɗarin cerebrovascular shine makonni 4-6, tare da cardialgia - kwanaki 12, tare da shan barasa - 7- Kwanaki 10, tare da rage yawan aiki kuma a matsayin taimako a wasanni - 10-21 days.

Pharmacology

Hanyoyin haɓaka ƙwayar cuta, anama gamma-butyrobetaine. Yana hana gamma-butyrobetaine hydroxynase, yana hana haɗin carnitine da jigilar daskararren sarkar acid ta hanyar membranes, kuma yana hana tara nau'ikan kitse na unoxidized mai mai a cikin sel - abubuwanda ke haifar da acylcarnitine da acylcoenzyme A.

A karkashin yanayin ischemia, yana dawo da daidaituwa na tafiyar matakai na isar da oxygen da yawan amfani da shi a cikin sel, yana hana cin zarafin jigilar jigilar ATP, kuma a lokaci guda yana kunna glycolysis, wanda ke gudana ba tare da ƙarin amfani da oxygen ba. Sakamakon raguwa a cikin taro na carnitine, gamma-butyrobetaine tare da kaddarorin vasodilating yana haɓaka mai ƙarfi. Hanyar aiki yana ƙayyade bambancin tasirin magunguna: haɓaka haɓaka, rage alamun damuwa da damuwa na jiki, kunna nama da rigakafin ƙwaƙwalwar mutum, tasirin cutar zuciya.

Game da mummunar cutar ischemic a cikin myocardium, yana rage jinkirin samuwar yankin necrotic kuma yana gajarta lokacin murmurewa. Tare da rashin karfin zuciya, yana kara yawan kwanciyar hankali na mutum, yana kara karfin motsa jiki, da kuma rage yawan kamuwa da cutar angina. A cikin mummunar cuta da rashin lafiyar ischemic na wurare dabam dabam na haɓakar cerebral yana inganta wurare dabam dabam na jini a cikin ischemia, yana ba da gudummawa ga sake rarraba jini a madadin yankin ischemic. Inganci ga cututtukan jijiyoyin bugun gini da na dystrophic na fundus. Yana da sakamako na tonic akan tsarin juyayi na tsakiya, yana kawar da rikice-rikice na aiki na tsarin juyayi a cikin marasa lafiya tare da shan barasa tare da ciwo na cirewa.

Side effects

Daga tsarin zuciya: da wuya - tachycardia, canje-canje a cikin karfin jini.

Daga gefen tsarin juyayi na tsakiya: da wuya - tashin hankalin psychomotor.

Daga tsarin narkewa: da wuya - alamomin dyspeptik.

Allergic halayen: da wuya - fata itching, redness, fuka, kumburi.

Don maganin baka ko na cikin jijiya: a matsayin wani ɓangare na hadaddun farjin cututtukan zuciya na zuciya (angina pectoris, myocardial infarction), raunin zuciya, rashin tausayi na zuciya, dishormonal cardiomyopathy, a matsayin wani ɓangare na hadaddiyar farfaɗar cututtukan cututtukan ƙwaƙwalwa da rashin rikicewar ƙwayar cuta (bugun jini da rashin ƙwaƙwalwar ƙwayar cuta), rage aiki, ƙarancin jiki (ciki har da a cikin 'yan wasa), bayan aikin da ya dace don hanzarta farfadowa, cire ciwo a cikin shan barasa (a hade tare da takamaiman aikin likita, barasa ZMA).

Don gudanar da tsarin parabulbar: rikicewar yanayin jijiyoyin jini a cikin retina, hemophthalmus da cututtukan fata na kashin baya daban-daban na etiologies, thrombosis na jijiya na tsakiya da reshenta, retinopathy na etiologies daban-daban (ciki har da masu ciwon sukari da hauhawar jini) - kawai don maganin parabulbar.

Mene ne Meldonium

Meldonium, wanda aka fi sani da Mildronate, magani ne wanda ke haɓaka tsarin aiki na jiki. Farfesa a fannin ilimin kimiyyar likitanci, Ivar Kalvins, wanda a yanzu shi ne shugaban sashen sashen Cibiyar Latvian da ke Riga. A cikin bincikensa, Calvins ya sami wani keɓaɓɓen abu, gamma-butyrobetaine, wanda ke da amfani ga dukiyar sake amfani da albarkatun tantanin halitta idan aka shigar da jikin mutum zuwa matsanancin nauyin da aka saba dasu. Gyara gamma-butyrobetaine ya kirkiro tushen Meldonium dihydrate, wanda shine babban aikin Mildronate.

Abun haɗin gwiwa da ka'idodin aiki na Mildronate

Tun lokacin da aka kirkiro shi, Mildronat ya nuna sha'awar soji a tsakanin sojoji da 'yan wasa - duk yan koyo da kwararru. An yi amfani dashi sosai a kusan dukkanin ƙasashe na sararin samaniya bayan Soviet, tunda mutane suna da imani game da abubuwan al'ajabi na Meldonius, musamman, iyawarsa na ƙaruwa da ƙarfi na jiki da saurin canji na ɗan adam. Koyaya, babu wata hujja ta kimiyya game da wannan da'awar.

Koyaya, a cikin 2016, Mildronate an amince da shi a matsayin magani wanda aka haramta wa mahalarta babban wasanni. A lokaci guda, shahararrun ƙwayoyi a tsakanin talakawa ya ƙaru. Bukatar da ba a taɓa yin amfani da ita ba ga Mildronate saboda kayan aikin magunguna ne.

Don haka, kyawawan kaddarorin Meldonium sun haɗa da iyawarsa don kare ƙwayar zuciya daga ɗauka a manyan lodi. A kowane tsari na rayuwar ɗan adam, ana cinye makamashi, watau albarkatun makamashi na cikin gida yana ƙonewa. Wadannan albarkatun sun kasance sunadarai da glycogen. Lokacin da jiki yayi aiki na dogon lokaci a iyakar ƙarfin, sel sun fara wahala daga rashin isashshen sunadarin oxygen, kuma lalacewar abubuwan gina jiki basu da tasiri sosai. Yin sarrafa glycogen yana buƙatar ƙara ƙoƙari, yayin da ake ƙona kitse a hankali. Tare da raunin oxygen, ƙwayoyin ba su da lokaci don sarrafa kitsen gaba ɗaya, wanda shine dalilin da yasa "an rufe" jikin tare da samfuran lalata. Wannan yana tattare da haɗarin cututtuka daban-daban na tsarin zuciya da jijiyoyin jini, alal misali, cututtukan zuciya na zuciya.

Mildronate baya yarda a sarrafa kitsen idan mutum yaji ƙarancin iskar oxygen. Yana kunna rushewar glycogen, don haka sakin kuzari mai sauri da kuma kiyaye ragowar iskar oxygen a cikin sel. A cikin sharuddan masu sauki, kayan Meldonium shine sanya mutum a cikin wani yanayi na adana makamashi kuma ya bar jiki ya yi aiki tare da ƙarancin lahani ga zuciya.

Koyaya, kayan amfani na Mildronate basu iyakance ga wannan ba. Wannan maganin yana iya kawo fa'idodi da yawa ba wai kawai a wasanni ba, har ma a zaman cikon aiki don cikakken magani game da cutuka daban-daban.

Amfanin Mildronate ga maza da mata

Tun da kaddarorin Meldonium suna taimaka wa jure damuwa ta jiki ba tare da lahani ga lafiyar ba, tana jurewa da hana ischemia tare da magunguna masu ƙwararru. Bugu da kari, yana kare sel zuciya daga lalacewa, yana kara juriya ga dan adam gaba daya danniya da damuwa.

Sauran kayan aikin warkewa na Mildronate sun haɗa da iyawarsa na hanzarta zagayawa cikin jini a cikin kwakwalwa da kuma retina, dangane da abin da ake yin shi sau da yawa don rigakafin ƙwanƙwasa jini.

Dokoki don shigowa da daidaitaccen sashi na Mildronate

A cikin yawancin kantin magani, ana iya siyar da Mildronate ta fannoni daban-daban: ana siyar da shi a cikin capsules da allunan 250 da 500 MG, kamar yadda kuma a cikin mafita don allura. Lokacin ɗaukar wannan magani, dole ne a bi umarnin a hankali don rage haɗarin cutarwa. Sashi na Mildronate ya dogara da dalilin aikinta. Kuna iya lissafin sashi da kanka, a cikin nauyin 20 MG na Mildronate a 1 kilogiram na nauyi, amma ya fi kyau ku nemi shawarar kwararru da farko.

Aikace-aikacen Mildronate

Mutane masu shekaru sama da 18 suna amfani da Mildronate a cikin yanayin kiwon lafiya daban-daban, ba tare da la'akari da jinsi ba. A matsayinka na mai mulki, an wajabta shi don 'yan wasa ko ma'aikatan tunani, amma kuma an lura da shi ga waɗanda ke fama da ciwon sukari da kuma rikice-rikice na tsarin zuciya, hauhawar jini da mutanen da ke da yawan barasa.

Don 'yan wasa

Abubuwan da ke cikin Mildronate za su kasance da godiya da farko daga masoya na salon rayuwa mai aiki. Yana dawo da iskar oxygen a cikin kyallen takarda yayin horarwa mai wahala, yana hana tarin gubobi mai cutarwa da sharar gida daga aiki, kuma yana kare sel daga lalacewar da basu dace ba.

Don dawo da makamashi, masu motsa jiki yakamata su ɗauki kwalliya 250 mg 4 sau a rana don makonni 2. Har ila yau, amfanin da za a iya samu shine zai kawo makon 2 na allurar Mildronate - 500 MG sau ɗaya a rana.

Tare da shan giya

Meldonium yana da tasiri mai amfani a cikin tsarin juyayi na autonomic na tsakiya kuma ana amfani dashi sau da yawa a cikin yaki da dogaro da barasa, saboda yana taimakawa wajen daidaita ayyukan tunani kuma yana taimakawa wajen magance alamomin "cirewar ciwo".

Don lura da cututtukan ƙwayar cuta, ana amfani da Mildronate a sashi na 500 MG. Ana ɗaukar shi sau 4 a rana don jimlar tsawon 1 zuwa 2 makonni.

Har ila yau, allurar Mildronate tana ba da fa'idodin magani. A cikin wannan halin, ana aiwatar da hanyar sau 2 a rana a 500 MG don daidai wannan lokacin.

Tare da arrhythmias na zuciya

Mildronate ya tabbatar da darajar ta a cikin halayen rashin lafiyar zuciya. Yana ƙaruwa da yawan matsewar zuciya a cikin buguwa ta zuciya, hakan ya hana haɓakar angina pectoris, daidaituwa wurare dabam dabam na jini. Don rigakafin cututtukan zuciya, ana amfani da Mildronate a cikin capsules na 0.5 - 1 g kowace rana. Lokacin da aka ba da shawarar magani shine 1 - 1.5 watanni.

Daga gajiya

An kuma ƙera Mildronate don gajiya mai wahala da ƙaruwar kasala sakamakon damuwa da damuwa ta jiki. Amfaninta a wannan cutar shine daidaita jini tare da iskar oxygen, sakamakon karuwar aiki, mutum yana iya zama mai kuzari kuma mafi kyawu ga yanayin damuwa.

Shin zai yiwu a rasa nauyi tare da taimakon Mildronate

A wasu halaye, ana amfani da allunan Mildronate don cire karin fam, amma a wannan yanayin, kuna buƙatar yin hankali yayin ɗaukar miyagun ƙwayoyi domin maimakon fa'idodin da ake so, ba ya cutar da jiki. Abubuwan da ke cikin Meldonium suna ba da gudummawa sosai ga asarar nauyi saboda ƙayyadaddun metabolism, amma ba a ba da shawarar amfani da shi azaman kayan aiki mai zaman kanta ba! Mildronate yana da tasirin da ake so kawai a hade tare da horar da motsa jiki da kuma daidaita tsarin abinci.

Lalacewa ko sakamako na Mildronate

Ga duk fa'idodin da yake da shi ga jikin ɗan adam, Mildronate na iya haifar da mummunar cutar ga jikin mutum idan kun wuce magani ko shan shi ba tare da shawarar likita ba. Meldonium yana da jerin gwanon sakamako wanda zai haifar da rashin jin daɗi. Koyaya, sun bayyana da wuya, kuma ƙarƙashin dokar amfani, cutar daga gare su za a rage. Daga cikin kaddarorin na Mildronate sun hada da:

• belching, ƙwannafi,
• tashin zuciya da amai
• nauyi a ciki
• samarin
• tashin hankali
• busa da kurji,
• rashin lafiyan fata haushi,
• itching

Bugu da ƙari, Mildronate yana da lahani a cikin sharuddan masu sana'a: don 'yan wasa, amfani da shi na iya zama ya ɓata tare da ficewa daga gasar, tunda Meldonium yana ɗayan magungunan WADA da aka haramta.

Mildronate Alcohol karfinku

A yanzu, babu takaddama kai tsaye ga amfani da Mildronate a hade tare da barasa. Koyaya, yawancin ƙwararrun likitocin ƙwararru basu bada shawarar hada Meldonium tare da samfuran da ke amfani da giya ba don hana cutarwa mai yiwuwa. Barasa na iya lalata abubuwan da ke cikin magani, kuma a wasu lokuta abubuwanda ke aiki na Mildronate na iya haifar da alamun bayyanar maye kuma suna haifar da kumburi a cikin karfin jini. Ga jikin mutum mai lafiya, yana yiwuwa cewa babu wata illa daga haɗuwar Meldonium tare da barasa, amma tabbas waɗannan canje-canjen ba za su amfana da masu cutar hawan jini ba.

Analogs na Meldonium

Don haka, analogues na Mildronate a halin yanzu ba su wanzu ba, kodayake ƙoƙarin neman madadin wakili tare da nau'ikan kaddarorin ba su daina ba. Daga cikin manyan abubuwan da ke tattare da abubuwa, ana iya lura da trimetazidine, wanda ayyukansa sun yi kama da na Meldonium, wato, haɓakar metabolism, amma mahimmin aikinsa ya sha bamban. Bugu da kari, ana kuma daukar shi haramun ne a wasannin.

Amma, duk da kyakkyawan suna, ana iya samun Meldonium a cikin magunguna, da kuma sauran nau'ikan magunguna, waɗanda suka haɗa da ƙwayar Meldonium mai narkewa. Daga cikinsu akwai:

• Angiocardyl
• Vasomag,
• Idrinol
• Cardionate
• Kayan aiki
• Midolat
• Mildroxin da sauransu.