Insulin juriya - alamu, magani, abinci

Jurewar insulin shine ragewar ji na kasusuwa zuwa ga aikin insulin, wanda zai iya bunkasa idan babu wasu cututtuka masu tsauri. A farkon matakan, jurewar insulin kusan babu wani tasiri ga zaman lafiya, kuma ana iya gano wani karkatacciyar hanyar kawai ta hanyar canza bayanan gwaji (jini).

Insulin juriya: alamu da magani. Abincin don juriya insulin

Jurewar insulin shine amsawar ilimin halittar jiki wanda kyallen jikin yake aiwatar da aikin insulin. Ba shi da mahimmanci inda insulin ya fito, daga farji (endogenous) ko daga injections (exogenous).

Jurewar insulin yana ƙaruwa da alama ba kawai nau'in ciwon sukari na 2 kawai ba, har ma da atherosclerosis, bugun zuciya, da mutuwar kwatsam sakamakon jirgin ruwa mai ruɗu.

Ayyukan insulin shine tsara tsarin metabolism (ba kawai carbohydrates ba, har ma da kitse da sunadarai), da kuma hanyoyin tafiyar da mitogenic - wannan shine haɓaka, haifuwa daga sel, kwayar halittar DNA, ƙirar ƙirar.

Ra'ayin yau da kullun na jure insulin ba'a iyakance shi ga rikicewar metabolism da haɗarin haɗari na nau'in ciwon sukari na 2 Hakanan ya haɗa da canje-canje a cikin metabolism na kitse, sunadarai, bayanin asalin. Musamman, juriya na insulin yana haifar da matsaloli tare da ƙwayoyin endothelial, waɗanda ke rufe ganuwar tasoshin jini daga ciki. Saboda wannan, toshewar tasoshin, da kuma atherosclerosis na ci gaba.

Bayyanar cututtuka na juriya da ganewar asali

Ana iya zargin ku da ciwon jurewar insulin idan alamunku da / ko gwaje-gwajen sun nuna cewa kuna da ciwo na rayuwa. Ya hada da:

kiba a kugu (ciki),
hauhawar jini (hawan jini),
mummunan gwajin jini ga cholesterol da triglycerides,
gano furotin a cikin fitsari.

Kiba na ciki shine mafi yawan alamun juriya na insulin juriya. A wuri na biyu shine hauhawar jini mai yawan jini (hawan jini). Kadan sau da yawa, mutum ba shi da kiba da hauhawar jini, amma gwajin jini na cholesterol da ƙera sun riga sun yi muni.

Gano juriya ta insulin amfani da gwaje-gwaje matsala ce. Domin tarowar insulin a cikin jini na jini na iya bambanta sosai, kuma wannan al'ada ce. Lokacin da ake nazarin insulin plasma na azumi, ka'idodin ya kasance daga 3 zuwa 28 mcU / ml. Idan insulin ya fi al'ada a jinin azumi, yana nufin cewa mara lafiyar yana da maganin haɓaka jini.

Increasedarin yawan insulin a cikin jini yana faruwa ne yayin da farji ya samar da ƙari daga ciki don rama ƙarfin juriya na insulin a cikin kyallen. Wannan sakamakon bincike yana nuna cewa mai haƙuri yana da babban haɗarin kamuwa da cututtukan type 2 da / ko cutar zuciya.

Hanyar mafi daidaituwa don tantance juriya na insulin ana kiranta hyperinsulinemic insulin matsa. Ya ƙunshi ci gaba da shigarwar cikin aiki na insulin da glucose na tsawon awanni 4-6. Wannan hanya ce mai aiki, saboda haka ba a amfani da ita a aikace. An iyakance ga gwajin jini na azumi don matakan insulin plasma.

Nazarin ya nuna cewa ana samun juriya na insulin:

10% na duk mutane ba tare da rikicewar rayuwa ba,
a cikin 58% na marasa lafiya da hauhawar jini (hawan jini sama da 160/95 mm Hg),
a cikin 63% na mutanen da ke fama da hyperuricemia (serum uric acid sun fi 41 μmol / l a cikin maza kuma sama da 387 μmol / l a cikin mata),
a cikin 84% na mutanen da ke da jini mai yawa (triglycerides mafi girma daga 2.85 mmol / l),
a cikin 88% na mutanen da ke da ƙananan matakan “mai kyau” cholesterol (a ƙasa 0.9 mmol / l a cikin maza kuma ƙasa da 1.0 mmol / l a cikin mata),
a cikin 84% na marasa lafiya da nau'in ciwon sukari na 2,
Kashi 66% na mutane masu fama da rashin kyawun glucose.

Lokacin da kuka yi gwajin jini a cikin cholesterol - kada ku duba yawan cholesterol, amma dabam “mai kyau” da “mara kyau”.

Yadda insulin ke sarrafa metabolism

A yadda aka saba, kwayar insulin ta daure wa mai karbar ta ta fuskar sel a tsoka, mai, ko hanta hanta. Bayan wannan, autophosphorylation na insulin receptor tare da halartar tyrosine kinase da haɗi mai zuwa tare da canza mai karɓa na insulin 1 ko 2 (IRS-1 da 2).

Kwayoyin IRS, bi da bi, suna kunna phosphatidylinositol-3-kinase, wanda ke motsa motsin GLUT-4. Mai ɗaukar glucose ne a cikin tantanin ta cikin membrane. Irin wannan kayan aikin yana ba da kunnawa na aiki na rayuwa (jigilar glucose, glycogen synthesis) da tasirin mitogenic (kwayar halittar DNA) ta insulin.

Abincin glucose da ƙwayoyin tsoka, hanta da ƙwayar tsoka,
Kira na glycogen a cikin hanta (ajiyar “glucose din” cikin sauri ”a ajiye),
Kama amino acid ta hanyar sel,
Kwayar halittar DNA
Tsarin furotin
Hadaddiyar acid din
Kai jigilar kai Ion

Lipolysis (fashewa da tsotse nama tare da shigar da m acid a cikin jini),
Gluconeogenesis (canji na glycogen a cikin hanta da glucose cikin jini),
Apoptosis (lalata kansa daga sel).

Lura cewa insulin yana toshe faduwar tsohuwar nama. Abin da ya sa, idan matakin insulin a cikin jini ya haɓaka (hyperinsulinism shine maimaitawa tare da juriya na insulin), to rasa nauyi yana da matukar wahala, kusan ba zai yiwu ba.

Abubuwan da ke haifar da juriya na insulin

Jurewar insulin shine matsalar babban adadin mutane duka. An yi imani da cewa shi ya haifar da kwayoyin halitta wanda ya zama babba lokacin juyin halitta. A cikin 1962, ana tunanin cewa juriya insulin shine tsarin rayuwa yayin da ake fama da yunwar. Domin yana inganta yawan kitse a jiki a lokacin wadataccen abinci.

Masana kimiyya sun fara fama da beraye na dogon lokaci. Waɗanda suka fi tsayi rayuwa su ne waɗanda aka gano suna da matsin lambar insulin ta jabu. Abin baƙin ciki, a cikin yanayin zamani, tsarin juriya na insulin yana “aiki” don haɓaka kiba, hauhawar jini da nau'in ciwon sukari na 2.

Nazarin ya nuna cewa marasa lafiya da ke da nau'in ciwon sukari na 2 suna da lahani na ƙwayoyin cuta a cikin watsa siginar bayan an haɗa insulin tare da mai karɓar su. Wannan ana kiran shi lahani postreceptor. Da farko dai, ana canza fasarar mai jigilar glucose GLUT-4.

A cikin marassa lafiya da ke fama da ciwon sukari na 2, an gano cewa gurbataccen bayanin wasu kwayoyin halittar da ke samar da metabolism na glucose da lipids (fats). Waɗannan nau'ikan halittar jini ne na glucose-6-phosphate dehydrogenase, glucokinase, lipoprotein lipase, fat acid synthase da sauransu.

Idan mutum yana da tsinkayar halittar jini ga kamuwa da ciwon sukari na 2, to, ana iya gane shi ko kuma ba zai haifar da cututtukan metabolism da ciwon suga ba. Ya dogara da salon rayuwa. Babban abubuwan da ke haifar da haɗari shine abinci mai narkewa, musamman yawan amfani da carbohydrates mai ladabi (sukari da gari), da ƙananan aikin jiki.

Mene ne hankali ga insulin a cikin nau'ikan jikin jiki

Don lura da cututtuka, ƙwayar insulin na ƙwayar tsoka da ƙwayar adipose, gami da ƙwayoyin hanta, suna da mahimmancin gaske. Amma shin matsayin jurewar insulin na wadannan sel din daya ne? A shekara ta 1999, gwaje-gwajen sun nuna cewa a'a.

A yadda aka saba, don kashe 50% na lipolysis (fashewar kitse) a cikin tso adi nama, taro na insulin a cikin jini bai wuce 10 mcED / ml ya isa ba. Domin kashi 50% na sakin glucose a cikin jini ta hanta, kimanin 30 mcED / ml na insulin a cikin jini an riga an buƙata. Kuma don haɓaka tasirin glucose ta ƙwayar tsoka ta hanyar 50%, ana buƙatar taro insulin a cikin jini na 100 mcED / ml kuma ana buƙatar mafi girma.

Muna tunatar da ku cewa lipolysis shine rushewar tsoka nama. Ayyukan insulin yana hana shi, kamar yadda yaduwar glucose ta hanta. Kuma yawan ƙwayar glucose na tsoka ta hanyar insulin, akasin haka, yana ƙaruwa. Lura cewa a cikin nau'in ciwon sukari na 2 na mellitus, abubuwan da aka nuna na yawan maida hankali na insulin a cikin jini an canza su zuwa dama, i.e., zuwa karuwa a cikin juriya na insulin. Wannan tsari yana farawa tun kafin ciwon sukari ya nuna kanta.

Halin ƙirar jikin mutum zuwa insulin yana raguwa saboda yanayin tsinkaye, kuma mafi mahimmanci - saboda yanayin rayuwa mara kyau. A ƙarshe, bayan shekaru da yawa, ƙwayar cutar ta daina yin fama da matsananciyar damuwa. Sannan suna bincikar cutar sukari “real” type 2. Yana da fa'idodi sosai ga mai haƙuri idan an fara kula da cututtukan metabolism da wuri-wuri.

Menene bambanci tsakanin juriya na insulin da cututtukan metabolism

Ya kamata ku sani cewa juriya ta insulin yana faruwa a cikin mutane tare da wasu matsalolin kiwon lafiya waɗanda ba a haɗa su da ma'anar “metabolic syndrome”. Wannan shi ne:

polycystic ovary a cikin mata,
na kullum na koda
cututtuka
glucocorticoid far.

Jurewar insulin wani lokaci yakan zama ne yayin daukar ciki, kuma yakan wuce bayan haihuwa. Hakanan yakan tashi tare da tsufa. Kuma ya dogara da salon rayuwar da tsofaffi ke jagoranta, shin zai haifar da ciwon sukari na 2 da / ko matsalolin zuciya. A cikin labarin "Ciwon sukari a cikin tsofaffi" zaku sami bayanai masu amfani da yawa.

Jurewar insulin shine sanadin ciwon sukari na 2

A cikin nau'in 2 na ciwon sukari na mellitus, juriya na insulin ƙwayoyin tsoka, hanta da ƙwayar adipose suna da mahimmancin asibiti. Sakamakon asarar hankali zuwa insulin, karancin glucose yana shiga kuma yana “ƙonewa” a cikin ƙwayoyin tsoka. A cikin hanta, saboda wannan dalili, bazuwar glycogen zuwa glucose (glycogenolysis) ana aiki, kazalika da haɗin glucose daga amino acid da sauran "albarkatun ƙasa" (gluconeogenesis).

Maganin jurewar insulin na tsoput nama yana bayyana ne a gaskiyar cewa tasirin maganin insulin yana rage rauni. Da farko, ana kashe wannan ne ta hanyar samar da insulin daga cikin jiki. A cikin matakai na gaba na cutar, mafi yawan kitse ya karye cikin glycerin da mai mai kyauta. Amma a wannan lokacin, rasa nauyi baya kawo farin ciki da yawa.

Glycerin da kitse mai mai kyauta suna shiga hanta, Inda ake samun wadataccen lipoproteins mai yawa daga garesu. Waɗannan ƙananan barbashi ne masu haɗari waɗanda aka ajiye akan bangon jijiyoyin jini, da kuma atherosclerosis na ci gaba. Yawan adadin glucose, wanda ya bayyana sakamakon glycogenolysis da gluconeogenesis, shima ya shiga cikin jini daga hanta.

Jurewar insulin da alamomin cututtukan metabolism a jikin dan adam sun gabaci cigaban ciwon sukari mellitus. Saboda juriyawar insulin na shekaru da yawa an biya sakamakon yawan insulin ta hanyar ƙwayoyin beta na pancreas. A irin wannan yanayin, ana lura da ƙara yawan tattarawar insulin a cikin jini - hyperinsulinemia.

Hyperinsulinemia tare da glucose na jini alama ce ta jure insulin da kuma haɗarin ci gaba da ciwon sukari na 2. A tsawon lokaci, ƙwayoyin beta na pancreatic ba sa iya jure nauyin don rama ƙarfin jurewar insulin. Suna haifar da ƙasa da insulin ƙasa, mai haƙuri yana da sukari jini da ciwon sukari.

Da farko dai, kashi na 1 na asirin insulin ya baci, i.e., saurin sakin insulin a cikin jini domin daukar nauyin abinci. Kuma basal (asalin) asirin insulin ya wuce kima. Lokacin da matakin sukari na jini ya hauhawa, wannan yana ƙara haɓaka jarin insulin nama kuma yana hana aikin ƙwayoyin beta cikin ɓoye insulin. Wannan hanyar don inganta ciwon sukari ana kiranta "gubar glucose."

Insulin juriya da hadarin zuciya

An san cewa a cikin marasa lafiya da ke dauke da ciwon sukari na 2, yawan cututtukan zuciya yana ƙaruwa sau 3-4, idan aka kwatanta da mutane ba tare da rikice-rikice na rayuwa ba. Yanzu mutane da yawa masana kimiyya da masu aikin kwantar da hankali sun yarda cewa juriya na insulin kuma, tare da shi, hyperinsulinemia babban haɗari ne na haɗarin bugun zuciya da bugun jini. Haka kuma, wannan haɗarin baya dogaro ko mara lafiyar ya kamu da ciwon sukari ko a'a.

Tun daga 1980s, bincike ya nuna cewa insulin yana da tasirin atherogenic kai tsaye akan bangon jijiyoyin jini. Wannan yana nufin cewa allunan atherosclerotic da kuma takaitaccen ƙwayar sel na gudana a ƙarƙashin aikin insulin a cikin jinin da ke gudana a cikin su.

Insulin yana haifar da yaduwa da ƙaura daga ƙwayoyin tsoka mai santsi, ƙirar lipids a cikinsu, yaduwar fibroblasts, kunnawar tsarin coagulation na jini, da raguwa a cikin aikin fibrinolysis. Don haka, hyperinsulinemia (haɓaka taro na insulin a cikin jini saboda juriya na insulin) babban mahimmanci ne na haɓakar atherosclerosis. Wannan na faruwa tun kafin bayyanar nau'in ciwon sukari na 2 a cikin haƙuri.

Nazarin ya nuna bayyananniyar dangantakar kai tsaye tsakanin matakin insulin juriya da dalilai masu haɗari ga cututtukan zuciya. Insulin juriya yana haifar da gaskiyar cewa:

ƙurar kiba ciki,
bayanin martaba na cholesterol ya kara tabarbarewa, da kuma wasu sifofi daga “mummunan” cholesterol a jikin bangon jijiyoyin jini,
da alama jini clots a cikin tasoshin yana ƙaruwa,
bango na carotid artery ya zama yayi kauri (lumen turancin jijiya).

Wannan ingantacciyar dangantakar an tabbatar da duka a cikin marasa lafiya masu fama da ciwon sukari na 2 da kuma cikin mutane ban da shi.

Insulin juriya magani

Hanya mai kyau don magance juriya na insulin a farkon farkon nau'in ciwon sukari na 2, har ma mafi kyau kafin ya bunkasa, shine amfani da abincin da ke ƙuntata carbohydrates a cikin abincin ku. Don zama daidai, wannan ba hanya ba ce don magance juriya na insulin, amma don sarrafa shi. Dietarancin carbohydrate mai narkewa tare da juriya na insulin - dole ne a bi shi don rayuwa.

Bayan kwanaki 3-4 na cin abinci na juriya na insulin juriya, yawancin mutane suna lura da haɓakawa da lafiyar su. Bayan makonni 6-8, gwaje-gwaje sun nuna cewa “mai kyau” cholesterol a cikin jini ya hau kuma “mara kyau” ɗaya ya faɗi. Kuma har ila yau matakin triglycerides a cikin jini ya ragu zuwa al'ada. Wannan yana nufin cewa hadarin atherosclerosis ya ragu sau da yawa.

A halin yanzu babu ainihin magani don juriya na insulin. Kwararru a fannin ilimin halittu da ilimin halitta suna aiki akan hakan. Kuna iya sarrafa jure insulin da kyau ta bin tsarin karancin carb. Da farko dai, kuna buƙatar dakatar da cin abinci mai narkewa na carbohydrates, watau sukari, Sweets da farin kayayyakin gari.

Tare da juriya na insulin, metformin (siofor, glucophage) yana ba da sakamako mai kyau. Yi amfani da shi ban da abincin, kuma ba a maimakon shi ba, kuma yi shawara da likitanka farko game da shan kwaya. Kowace rana muna bin labarai a cikin maganin juriya na insulin. Halittar zamani da ilimin halittar jiki suna yin mu'ujizai na gaske. Kuma akwai fata cewa a cikin shekaru masu zuwa za su iya kawo karshen wannan matsalar. Idan kana son sanin farko, biyan kuɗi zuwa wasiƙarmu, kyauta ce.

Menene haɗarin juriya na insulin?

Ko da a cikin mutane ba tare da manyan canje-canje a cikin metabolism ba, juriya na insulin yana haifar da aiwatar da tsufa da wuri, an san shi a yau cewa yana da alaƙa da mummunan cututtukan zuciya da rikice-rikice masu haɗarin su (bugun jini, bugun zuciya, mummunan haɗarin cerebrovascular, ciwon sukari mai ciwon sukari, da dai sauransu).

Juriya insulin yadu sosai. A cikin 10-15% na manya (ba tare da cututtukan cututtukan fata da cututtukan fata ba) za a iya gano su kwatsam, tare da kowane binciken. Kuma wannan yana nufin cewa dubban mutane ba wai kawai ba su san game da shi ba, har ma suna gaban cututtukan haɗari!

Yana iya ɗaukar cewa jurewar insulin babban maƙiyi ne kuma ɓoyayyen abokin gaba na lafiya, amma a zahiri wannan rudanin yana da sabani sosai, saboda karkacewa ana iya tuhumarsa a gaban takamaiman matsalolin bayyanar da walwala.

Misali, dukkan mata, musamman mata masu matsakaitan shekaru, sun saba da matsalar kiba. Ya zo lokacin da karin fam a zahiri ya haɗu tare da jiki, kusan babu wuya a rasa su, babu kayan abinci masu taimako. Kuma yana haifar da jin cewa nauyin jiki ya fi yawa a cikin ciki - wannan shine dalilin da ya sa mata da yawa ke mafarkin rasa nauyi a kugu, yin ɗimbin latsawa, ba da mahimmancin ga sauran sassan jiki ba. A halin yanzu shekaru da jari na adipose nama a ciki (wanda ake kira kiba na ciki, bisa ga nau'in tsakiya) sune abubuwa biyu masu mahimmanci waɗanda ke haifar da haɓakar insulin da tallafawa ƙarfafawa.

A cikin mata bayan shekaru 35, daban-daban cututtukan haila, wanda a wannan zamani ba tukuna haifar da ci gaban cututtuka, amma ƙirƙirar "hadari" a cikin jiki. Sauye-sauye a cikin abubuwan estrogen da testosterone (kuma tun kafin a fara menopause), raguwa a cikin abubuwan da ke tattare da kwayoyin hodar iblis da kuma ƙaddamar da kwatankwacin hormones mai damuwa - adrenaline, cortisol - duk wannan da farko yana tasiri ga lafiyar jiki. A hankali yana tattara matsalolin da ke da alaƙa da juna: kiba, karuwar cholesterol a cikin jini, hawan jini. Jurewar insulin zai iya zama duka sakamakon waɗannan canje-canje a cikin jiki, da abokin aboki mai aminci.

Taimakawa ga haɓakar insulin mummunan halaye, rashin motsa jiki, abinci mai gina jiki mai sauri kuma gabaɗaya karancin abinci. Af, rashin abinci mai kyau da sauran ƙuntatawa na abinci zai iya danganta ga ƙarancin abinci mai gina jiki: jiki baya samun lafiya daga garesu, kuma kullun "juyawa" - zubar da nauyi da ƙima yana ƙaruwa da halayyar insulin juriya.

Idan kuna tunani game da shi, to, a cikin rayuwar kowannenmu akwai aƙalla aƙalla daga cikin abubuwan da aka lissafa masu cutarwa, don haka idan wasu matsalolin sun dame ku na dogon lokaci da mahimmanci (ba za ku iya rasa nauyi ba, kullun kuna da hawan jini, ciwon kai da rauni), yakamata ku nemi likita kuma ku bayyana ba shi cikakken hoto na alamunsa. Sau da yawa dot duk Ina taimaka wa endocrinologist da gudanar da gwaje-gwaje da yawa (glucose, glucose test glucose, haemoglobin glycated, insulin resistance index, da sauransu).

Matsayin insulin a cikin jiki

Insulin shine mafi mahimmancin kwayoyin da ke ɓoye a cikin ƙwayar cuta, kuma kadai tsoka mai jikin mutum wanda ke saukar da yawan glucose a cikin jini. Insulin yana da nasaba da halaye masu mahimmanci na halitta, alal misali, yana kunna samuwar sunadarai a cikin tsokoki, yana tallafawa tarin fats a cikin hanta, amma sakamako ne na tsari dangane da glucose wanda ke samar da tushen ayyukansa na musamman.

Yawancin kyallen takarda a cikin jiki sun dogara da kasancewar insulin: wannan shine, da farko, tsoka da mai ƙashi (da sauran tsokoki, sai dai mai juyayi). Anan, insulin yana aiki kamar maɓalli - yana buɗe damar samun glucose a cikin sel, inda ake amfani dashi don makamashi, kuma yana ƙonewa. Idan wannan injin din ya daina aiki, sel zasu zama insulin hankali, suka bunkasa insulin juriya.

Tambayoyi suka rage

Za ku iya yin alƙawari koyaushe don samun cikakken bayani daga ƙwararrun sashen shawarwarinmu ta waya:

Artemyeva Alla Anatolyevna

Likita endocrinologist, mafi girman cancanta. Memba na kungiyar Endocrinological Society ta kasar Rasha. Kwarewa shekaru 32.

Maskaeva Valentina Olegovna

Likita endocrinologist, kwarewar aiki 3 years.

Nazarin duban dan tayi na glandar thyroid da glandon parathyroid

Abubuwan thyroid da parathyroid biopsy karkashin jagorancin duban dan tayi

Insulin juriya - menene cikin kalmomi masu sauƙi

Insulin juriya - wata kalma tana nuna wani abin al'ajabi lokacin da sel jikin ba su amsa daidai ga hormone: insulin. Wannan lamari ne mai yanke hukunci wanda ke haifar da nau'in ciwon sukari na 2, matakan farko na ciwon sukari da kuma ciwon suga.
Juriya insulin yana da alaƙa da kusancin kiba, amma mutane ba tare da wuce kima ba ko kiba suma suna iya zama sanadin hakan. A yanzu, an gano jurewar insulin a cikin kowane mutane 4 a duniya. Bayan haka kuma, ku da kanku kun fahimci mutane nawa da ba a sansu ba wadanda wannan bayanan ba ya aiki da su. Don haka lambobin na iya zama sau da yawa mafi girma kuma ... muni dangane da sakamakon.

Masu binciken na zamani sun tabbatar da cewa ana iya sarrafa juriya daga insulin ta amfani da hanyoyin warkewa wanda ke rage adadin insulin da jikin kansa ya samar, haka kuma ana daukar su ta hanyar injections na insulin.

Za'a iya samun raguwa cikin juriya na insulin tare da ƙananan carb da kayan abinci na ketogenic.

Matsayin insulin shine don ƙyale sel jikin su ɗauki glucose don haka daga baya za'a iya amfani dashi azaman "man" ko ajiyar kitse mai ƙarko. Hakanan yana nufin cewa glucose na iya ginawa cikin jini, wanda ke haifar da sukari mai yawa.

Lokacin da jiki ya zama rigakafin insulin, yana ƙoƙari ya jimre da wannan ta hanyar samar da shi a cikin adadi mai yawa. Wadanda ke yin rigakafi ga wannan kwayoyin sau da yawa suna samar da shi da yawa a cikin mutane fiye da masu lafiya.
Muhimmancin samarda insulin ana kiranta da suna hyperinsulinemia.

Bayyanar cututtukan Insulin

Halin da kansa, kamar wannan, ba shi da alamun cutar alama ko alamomi. Suna fara bayyana ne kawai lokacin jurewar insulin yana haifar da sakamako, irin su sukarin jini (tsawan tsawan jini).

Lokacin da wannan ya faru, ana yin rikodin alamun: gajiya, yunwa, ko karuwar ci, wahalar tattarawa, wanda kuma za'a iya kiran rikicewa. Akwai alamun bacci na rana, musamman bayan cin abinci. Sau da yawa mafi yawan yanayi mara kyau ya mamaye, rage aiki.

Sauran alamun da za a iya haɗawa a cikin janar na gaba ɗaya: ƙimar nauyi da kuma bayyanar mai a cikin ciki, ƙarancin kiba, lalata fata (bayyanar acrochordones - polyps sau da yawa masu launin fata a kan kafafu na bakin ciki a wuraren hargitsi, duhu na ɗakunan fata - black acanthosis, keratomas, papillomas, basilla hemangiomas - maki basur a jiki), hawan jini, hawan jini.

Lokacin da juriya na insulin ya zama mai ciwon sukari na farko ko nau'in ciwon sukari na 2, alamomin zasu haɗa da: haɓaka glucose na jini da sauran alamu na kamuwa da ciwon sukari na 2.

Sanadin Resulin Juriya

Yayinda har yanzu ba a fahimci ainihin abubuwan da ke haifar da juriya na insulin ba, abubuwan da ke haifar da ci gabansa sanannu ne.
Zai iya fara haɓakawa ƙarƙashin waɗannan dalilai masu kyau:

Yawan kiba ko kiba Lokacin da ƙayyadaddun kayan jikin mutum ya wuce da kashi ɗaya bisa uku ne kawai, ƙarancin kyallen ƙira zuwa insulin yana raguwa da kusan rabi.
A ci gaba da cuta na rayuwa.
Tare da abinci mai gina jiki waɗanda suke cikin adadin kuzari, carbohydrates, ko sukari. Yawancin abinci mai ladabi a cikin abinci tare da adana abubuwa, dyes, mai yawa sukari.
Salon rayuwa ko rashin motsa jiki.
Tare da aiki, tsawon lokaci ana ɗaukar steroids.
Tare da matsananciyar damuwa, rashin bacci na yau da kullun.
Tare da cutar ta Hisenko-Cushing, acromegaly, ovary polycystic, wasu cututtukan cututtukan cututtukan thyroid - hypothyroidism, thyrotoxicosis.
Masu binciken sun kuma lura da yadda kwayoyin halitta suka fada.
Daga cikin cututtukan da ake da su a cikin wannan yanayin sune cututtukan hanta, rheumatoid arthritis, gazawar na koda (gazawar koda), gazawar zuciya, sepsis, manyan wuraren ƙonewa, cachexia da dystrophy a cancer.

La'akari da duk abin da ke faruwa a jiki, yana haifar da juriya na insulin, masana kimiyya sun gano cewa yana bayyana a cikin mutanen da suke da yawanci, kusan ƙara yawan matakan insulin a cikin jininsu, kuma suna da mai mai yawa akan hanta da ƙwayar cuta.

Rashin rauni na rigakafi, tsufa, ciki, raunin da yawun aikin, shan sigari na iya taimakawa wajen bunkasa cutar.

Sakamakon rashin lafiyar insulin

Cutar ta baya bayan nan ta daina fama da yawan karuwar da kuma ci gaba da samarda insulin kamar yadda yake a da, mutum kuma ya kamu da ciwon sukari na 2.

Sakamakon da ya haifar na tsawon lokaci na rashin lafiyar insulin shine ya haɗu da haɓakar hepatosis mai ƙiba, hanta hanta, har ma da cutar kansa na wannan sashin. Alamar atherosclerosis na tasoshin ƙananan ƙananan hanji, rarrabewar jijiyoyin jijiyoyin jini gaba ɗaya, da kuma ƙwayoyin jijiyoyin jini suna bayyana kansu da sauri. Kuma a sakamakon - haɓakar infarction na zuciya da bugun jini.

Bayanin Cutar

Jurewar insulin shine yanayin da jiki baya amsa insulin da kyau. Wannan za a iya kwatanta shi da ƙin shan insulin ta hanyar ƙwayoyin jikin. Wannan shine babban fasalin nau'in ciwon sukari na 2.

Matsalar juriya insulin shine cewa yana shafar jikin mutum ta hanyoyi fiye da ɗaya.

Yana tilasta jiki samar da karin insulin, wanda ke haifar da karuwar ci da hauhawar jini, haka kuma samun nauyi. Insulin baya barin kitsen jiki ya rushe, saboda haka tare da juriya na insulin ba kusan yiwuwa a rasa nauyi ko yana da matukar wahala, sai dai in tare da yin amfani da azumin warkewa).

Duk da cewa ba a fahimci abubuwan da ke haifar da juriya ta insulin, amma a bayyane yake cewa akwai wata alaƙa tsakanin ci gabanta da ribarsa mai nauyi. Nazarin ya nuna cewa rage yawan adadin kuzari na iya dakatar da ci gaban cutar.

Bayyanar da juriya na insulin

Ana iya yin irin wannan binciken ta hanyar tattara anamnesis, ƙayyade kasancewar ciwon sukari mellitus, hauhawar jini, atherosclerosis a cikin dangi, an yanke shawarar cutar sankarar mahaifa yayin haila a cikin mace, da ta wuce UAC, fitsari don kasancewar albumin (furotin), gwajin jini na biochemical, kuma matakan insulin suma an ƙayyade su. a cikin kewayon 3-28 mcED / ml, kodayake wasu endocrinologists sunyi la'akari da al'ada NORM na 3-4 mcED / ml) da C-peptide a cikin jini.

NOMA IR insulin juriya insulin (rabo na azumi glucose zuwa matakin insulin) kuma yana da amfani ga ganewar asali. Matsakaicin wannan ƙayyadaddun bayanan bayanan har zuwa 2.7.

An bincika haƙuri a cikin glucose, an gwada gemocosylated haemoglobin, ana tantance matakin triglycerides da babban lipoproteins mai yawa.

An ƙaddara ma'aunin taro na jiki, tare da alam sama da 25 (kg / m²), haɗarin ci gaba ya riga ya yi girma. Hakanan yana da kyau a kula da karkatar da kugu, yana da kyau idan ya fi 89 ga mata, 102 cm ga maza.

Insulin juriya magani

Magungunan gargajiya an tsara ta tare da wakilai na hypoglycemic (Metformin, Glucofage, Acarbose, Troglizaton). Babban matakan hauhawar jini ana dakatar da su ta hanyar rage karfin kwayoyi, rage yawan kwayoyi - an wajabta magunguna masu rage kiba.

Komai, kamar yadda koyaushe, ga kowane alama, kamfanonin magunguna suna da nasu magani, ko ma fiye da ɗaya. Shin wannan yana kawar da cutar - Ba na jin haka. A gare ni wajibi ne don magance matsalar canjin abinci mai mahimmanci da tsarin abinci.

Shin yana yiwuwa a rage ko juyar da cutar

Tabbas akwai hanyoyin da za a rage tasirin sa kuma masu zuwa jerin abubuwan ne don taimaka muku cimma abin da kuke so.

Hanyoyi masu ƙarfi sun haɗa da:

Cararancin carb da kayan abinci na ketogenic.
Abubuwan rage yawan kalori.
Ciki mai kyau, tallatawa ta hanyar wasanni. Rabin sa'a na tsananin ƙwaƙwalwar jiki ko motsa jiki yana rage haɗuwa da glucose a cikin jini ba tare da taimakon insulin ba.
Daga magunguna na gargajiya, ana ba da shawarar ruwan 'ya'yan itace a kan furanni, da Berry da kuma kayan ganyayyaki.
Kuma a matsayin matsanancin yanayin - tiyata na asarar nauyi - liposuction, bandeji na ciki.

Wadannan hanyoyin suna kama da cewa sun taimaka wajen rage buƙatar jiki ga insulin da nauyi.

Abincin abinci don juriya na insulin - abinci mai gina jiki

Dole ne a zaɓi samfuran Carbohydrate tare da ƙarancin glycemic index, sunadarai da samfuran shuka yakamata suci cikin abincin.

Abincin yana samar da rage yawan abubuwan ƙonewa, abinci mai daɗi da gari, giya, taliya, shinkafa, madara, gishiri da sukari. Amma fats na kayan lambu, musamman ma Omega 3 da ba a gamsasu ba, suna da matukar muhimmanci ga jiki a wannan lokacin.

Masana ilimin abinci sau da yawa a cikin irin waɗannan lokuta suna ba da shawarar bin abincin Rum tare da ɗimbin man zaitun, kayan lambu, ganye. An ba da izinin cin naman dabino, kaji, kifin teku da abincin teku, samfuran lactic acid, kwayoyi, kowane irin tsaba (flaxseed, chia), tsaba.

Sauran hanyoyin sun yi imanin cewa tare da jurewar insulin, canje-canje a abinci ya ragu, yanayin za'a canza shi lokacin azumi gajerun sharuddan. Kwanaki 1-3, to, a wadataccen ranaku tare da abinci sau 3 a rana, kuma ba yanki 5-6 abinci a rana (wanda ke haifar da haɓaka matakin insulin a duk tsawon lokacin awoyi).

Tare da wannan jadawalin, zaku iya inganta hankalin ku zuwa insulin a cikin watanni 3-4, abinci kawai akan cikakken kwanaki ya kamata ya kasance tare da haramcin carbohydrates mai sauri - sukari, farin burodi, shinkafa, abinci mai sauri, yin burodi. Atsarin kuzarin (zai fi dacewa ba asalin dabba ba) da sunadarai, suna ƙara rashi magnesium, zinc, chromium, Vitamin D.

Tare da rashin chromium a cikin jiki, kiba yana haɓaka, yana ƙaruwa sosai so ga Sweets, wannan abun alama yana da nasaba da tsarin sukari. Chromium yana rage adadin glucose a cikin jini, yana haɓaka metabolism Wanda aka samu a cikin pears, hazelnuts, farin kaji, dankali, hanta naman sa.

Tare da hanya, zaka cire asara mai kadan daga cikin kugu da gabobin ciki, domin kawai a rana ta biyu ta azumin ne jikin ya fara jujjuya ajiyar kitse.

Wanene yana da wahalar yunwar, wato, zaɓi na yin azumin nafila gwargwadon tsarin 16/8, wato, awowi 16 na yunwar, misali daga sa'o'i 18 zuwa 10 da safe, daga 10 da safe zuwa 18 - kuna iya ɗaukar abinci 2 ko 3.