Mazzadinha
Akwai Choxine a cikin nau'ikan capsules: girman No. 2, shuɗi da shuɗi, abubuwan da ke ciki suna farin ko fari tare da ruwan hoda mai launin shuɗi (10 kowannensu a cikin kwari, a cikin kwali na kwali na 3 ko 6).
Abubuwan da ke aiki (a cikin capsule 1):
- Microcrystalline cellulose - 158.5 MG ko 153.5 MG,
- Sibutramine hydrochloride monohydrate - 10 MG ko 15 MG.
Abubuwa masu taimako: stearate alli.
Abun da ke ciki na kwanson kwalliya: gelatin, dye titanium dioxide, fenti mai launin shuɗi, fenti azorubine (capsules 10 mg).
Contraindications
- Hauhawar jini wanda ba a sarrafa shi ba (hawan jini sama da 145/90 mm Hg)
- Cututtukan zuciya, cututtukan zuciya, cututtukan zuciya, mara nauyi a cikin zuciya, cututtukan zuciya, cututtukan zuciya da na jijiyoyin jiki (tachycardia), cututtukan cututtukan zuciya
- Rashin rauni na koda da / ko aikin hanta,
- An kara hada shi,
- Cutar rashin hankali
- Rashin damuwa game da rashin cin abinci (bulimia nervosa ko anorexia),
- Sanya cututtukan zuciya mai kumburi
- Kasancewar Sanadin kwayoyin halitta masu kiba (hawan jini, da sauransu),
- Samarinda,
- Alamar rufewar Angle
- Abun magani, barasa ko magani mai dogaro,
- Shakarawar,
- Yin amfani da kwayar cutar antipsychotics, magungunan cututtukan cututtukan fata da sauran magunguna waɗanda ke aiki akan tsarin juyayi na tsakiya,
- Amfani na lokaci guda ko gudanarwa na makonni 2 kafin alƙawarin xarƙashin inginitors na rage rage abubuwa (alal misali ephedrine, ethylamfetamine, fenfluramine, phentermine, dexfenfluramine),
- Yin amfani da wasu kwayoyi don rage nauyin jiki na tsakiya, da kwayoyi waɗanda ke ɗauke da tryptophan kuma an wajabta su don rikicewar bacci,
- Yara ‘yan kasa da shekara 18
- Haihuwa da lactation
- Shekaru sama da 65,
- Rashin hankali ga kowane ɓangaren magungunan.
Dangi (dauki magani da taka tsantsan):
- Hauhawar jini (tsoka da sarrafawa),
- Rashin daidaituwa tsakanin jini,
- Tarihin arrhythmias,
- Coronary artery cuta (ciki har da tarihin)
- Paarancin na aiki da / ko aikin hanta na matsakaici mai sauƙi
- Nawantawan,
- Tarihin fi'ili da abin motsa jiki,
- Rashin lafiyar jijiyoyi, gami da tashin hankali da kuma jinkirta kwakwalwa (gami da tarihi).
Sashi da gudanarwa
Ana ɗaukar maganin kalolin capikiles a baki sau ɗaya a rana, kafin abinci ko lokacin abinci. An hadiye maganin kafatanin kuma an wanke shi da isasshen ruwan ko wani ruwa.
An saita kashi ɗaya akayi daban-daban kuma ya dogara da haƙuri na miyagun ƙwayoyi da tasirin aikinta. Maganin farko shine yawanci 10 mg. Idan ba a yarda da maganin ba, zaku iya fara shan shi tare da 5 MG.
Tare da raguwa a cikin nauyin jiki da ƙasa da 5% a cikin farkon watan farko na maganin, kashi na miyagun ƙwayoyi yana ƙaruwa zuwa 15 MG kowace rana. A cikin marasa lafiyar da suka kasa yin asarar 5% ko sama da nauyinsu na farko a cikin watanni 3, an dakatar da magani. Bai kamata a ci gaba da maganin ba koda kuwa, bayan asarar nauyi, mai haƙuri ya sake ƙara kilo 3 ko fiye.
Adadin jimlar magani na rage rage rage cutar bai wuce shekaru 2 ba, tunda babu bayanai kan amincin da kuma ingancin maganin tare da magani mai tsayi.
Ana gudanar da magani a karkashin kulawar likita tare da kwarewar aiki a cikin magance kiba. Ana ba da shawarar warkewa tare da motsa jiki da abinci.
Kungiyar magunguna
Hard gelatine capsules | Kafa 1. |
abubuwa masu aiki: | |
sibutramine hydrochloride monohydrate | 10/15 mg |
MCC | 158.5 / 153.5 mg |
magabata: alli stearate - 1.5 / 1.5 MG | |
wuya gelatin kwantena | |
don sashi na 10 MG: titanium dioxide - 2%, dye azorubine - 0.0041%, lu'u-lu'u mai launin shuɗi - 0.0441%, gelatin - har zuwa 100% | |
don sashi na 15 MG: titanium dioxide - 2%, shudi wanda aka daddale - 0.2737%, gelatin - har zuwa 100% |
Pharmacodynamics
Ragewar xin shiri ne hade wanda aikinsa saboda abubuwanda ke tattare dashi.
Sibutramine ne mai prodrug kuma yana yin tasirin sa a cikin vivo saboda metabolites (amines na farko da sakandare) wanda ke hana sake haɗarin monoamines (serotonin, norepinephrine da dopamine). Increaseara yawan abubuwan neurotransmitters a cikin synapses yana ƙara yawan ayyukan 5-HT-serotonin da masu karɓar adrenergic, wanda ke ba da gudummawa ga haɓaka satiety da raguwar buƙatun abinci, kazalika da haɓaka haɓakar samar da abinci. A hankali yana kunna beta3-adrenoreceptors, sibutramine abubuwa akan launin ruwan adiro mai launin ruwan kasa. Ragewar nauyin jikin mutum yana haɗuwa da karuwa a cikin ƙwayar plasma na HDL da raguwa a cikin adadin triglycerides, jimlar cholesterol, LDL da uric acid. Sibutramine da metabolites dinsa ba su tasiri sakin monoamines, kar a hana MAO, suna da ƙarancin ƙauna don adadi masu karɓa na neurotransmitter, gami da serotonin (5-HT15-NT1A5-NT1B5-NT2C), adrenergic (beta1-, beta2-, beta3-, alfa1-, alfa2-), dopamine (D1, D2), muscarinic, histamine (N1), benzodiazepine da masu karɓa (NMDA) masu karɓa.
MCC Abu mai enterosorbent ne, yana da kayan sihiri da tasirin rashin tsayayyen tsari. Yana ɗaure da kawar da ƙananan ƙwayoyin cuta, samfuran mahimmancin aikin su, abubuwan da ke tattare da fitattun abubuwa da yanayin ɗabi'a, ƙwayoyin cuta, ƙwararren ƙwayoyin cuta, da kuma wuce haddi na samfurori na rayuwa da metabolites da ke da alhakin ci gaba da guba.
Pharmacokinetics
Bayan gudanar da baki, yana sha da sauri daga narkewa kamar jijiyoyin jiki aƙalla 77%. A lokacin farkon farkon ta hanyar hanta, yana yin nazarin halittu a ƙarƙashin tasirin CYP3A 4 isoenzyme tare da samuwar metabolites masu aiki guda biyu - monodesmethylsibutramine (M1) da didesmethylsibutramine (M2). Bayan kashi daya na 15 MG Cmax cikin jini, M1 shine 4 ng / ml (3.2-4.8 ng / ml), M2 shine 6.4 ng / ml (5.6-7.2 ng / ml). Cmax an cimma shi bayan sa'o'i 1.2 (sibutramine), 3-4 awanni (M1 da M2). Mai Cin Gindi Sau da Cmax metabolites ta hanyar 30% kuma yana kara lokaci don isa gareshi ta 3 hours ba tare da canza kungiyar ta AUC ba. An rarraba shi da sauri akan kyallen takarda. Sadarwa tare da sunadarai shine 97 (sibutramine) da 94% (M1 da M2). Css Ana aiwatar da metabolites mai aiki a cikin jini na jini cikin kwanaki 4 bayan fara amfani da kusan sau 2 maida hankali a cikin jini jini bayan shan kashi ɗaya. T1/2 sibutramine - 1.1 hours, M1 - 14 hours, M2 - 16 hours. metabolites aiki hydrocarlation da conjugation tare da samuwar metabolites mara aiki, wanda kodan ke fitarwa.
Groupsungiyoyin haƙuri na musamman
Paul A halin yanzu akwai iyakantattun bayanai ba sa nuna kasancewar bambance-bambance na asibiti a cikin maza da mata.
Tsufa. Pharmacokinetics a cikin mutane masu lafiya masu lafiya (matsakaicin shekaru - shekaru 70) yayi kama da na samari.
Rashin wahala. Rashin ƙarancin raunin baya tasiri akan AUC na metabolites mai aiki M1 da M2, sai dai don metabolite M2 a cikin marasa lafiya waɗanda ke fama da ƙarshen ƙarancin ƙaddamarwar yanayin da ake fama da dialysis.
Rashin hanta. A cikin marasa lafiya da gazawar hanta na wucin gadi bayan kashi ɗaya na sibutramine AUC, metabolites mai aiki M1 da M2 suna 24% sama da na mutane masu lafiya.
Haihuwa da lactation
Tunda ya zuwa yanzu babu adadin karatu mai yawa game da amincin tasirin sibutramine akan tayi, an sanya wannan maganin lokacin daukar ciki.
Matan da ke da shekaru haihuwa ya kamata su yi amfani da rigakafin hana haihuwa yayin shan Symxin xin.
An haɗu da shi don ɗaukar Reduargin xin yayin shan nono.
Side effects
Mafi yawan lokuta, sakamako masu illa suna faruwa a farkon jiyya (a cikin makonni 4 na farko). Verarfinsu da frequencyarfinsu ya raunana na lokaci. Abubuwan da ke haifar da sakamako masu mahimmanci suna da laushi koyaushe. Abubuwan da ke haifar da sakamako, dangane da tasirin tsarin gabobi da tsarin gabobin, ana gabatar dasu a cikin tsari mai zuwa: sau da yawa (≥10%), sau da yawa (≥1%, amma tsarin juyayi na tsakiya: sosai sau da yawa - bushewar baki da rashin bacci, sau da yawa - ciwon kai, farin ciki, damuwa, paresthesia, da kuma canji a dandano.
Daga CCC: sau da yawa - tachycardia, palpitations, hauhawar jini, vasodilation.
Ana ganin tashin hawan jini cikin matsakaici da 1-3 mm Hg. da kuma matsakaici karuwa a cikin zuciya rate by 3-7 doke / min. A wasu halaye, ƙarin yawan faɗakarwa a hawan jini da na zuciya ba a cire su. Canje-canje na asibiti a cikin hawan jini da bugun jini ana yin rikodin su ne a farkon jiyya (a farkon makonni 4-8).
Amfani da Ragegin ® a cikin marasa lafiya da ke fama da hawan jini: duba "Contraindications" da "Umarnin na Musamman".
Daga tsarin narkewa: sau da yawa sau da yawa - asarar ci da kuma maƙarƙashiya, sau da yawa - tashin zuciya da kuma wuce haddi na basur. Tare da hali na maƙarƙashiya a cikin farkon zamanin, kula da yadda aikin kwashewa na hanji ya zama dole. Idan maƙarƙashiya ya faru, dakatar da ɗaukar magani.
A bangare na fata: sau da yawa - karuwar gumi.
A cikin lokuta mafi wuya, magani tare da sibutramine ya bayyana waɗannan abubuwan da ba a so na asibiti mai mahimmanci: dysmenorrhea, edema, mura-like syndrome, itching na fata, ciwon baya, ciki, hauhawar tashin hankali, ƙishirwa, rhinitis, ɓacin rai, amai, tashin hankali, damuwa, tashin hankali, juyayi, m interstitial nephritis, zub da jini, Shenlein-Genoch purpura (basur a cikin fata), tsotsewar jiki, thrombocytopenia, ƙarancin lokaci a cikin ayyukan hanta enzymes na hanta a cikin jini.
Yayin aiwatar da karatun bayan-tallace-tallace, an bayyana ƙarin halayen masu illa, waɗanda aka lissafa a ƙasa, ta tsarin tsarin:
Daga CCC: atrial fibrillation.
Daga tsarin rigakafi: halayen tashin hankali (daga rashes na matsakaici a kan fata da urticaria zuwa angioedema (edema na Quincke) da anaphylaxis)).
Rashin hankalin mutum: psychosis, jihohi na tunanin kashe kansa, kashe kansa da kuma tashin hankali. Idan irin waɗannan yanayi suka faru, dole ne a dakatar da maganin.
Daga tsarin juyayi: cramps, rauni na ɗan gajeren lokaci.
Daga gefen gabar hangen nesa: wahayin gani (mayafi a gaban idanun).
Daga tsarin narkewa: zawo, amai.
A bangare na fata da kasusuwa na jiki: alopecia.
Daga kodan da urinary fili: urinary riƙewa.
Daga tsarin haihuwa: rikicewar ciwan ciki / rashin haihuwa, rashin haihuwa, rashin daidaituwa yayin haila, zubar jini na cikin mahaifa.
Haɗa kai
Masu hana masu amfani da iskar shaka mara nauyi, gami da inhibitors na CYP3A 4 isoenzyme (gami da ketoconazole, erythromycin, cyclosporin) yana haɓakar ƙwayar plasma na sibutramine metabolites tare da karuwa a cikin zuciya da karuwa a asibiti a cikin rashin daidaituwa na QT.
Rifampicin, maganin rigakafin macrolide, phenytoin, carbamazepine, phenobarbital da dexamethasone zasu iya haɓaka metabolism na sibutramine. Yin amfani da magunguna da yawa a lokaci guda waɗanda ke haɓaka ƙwayoyin serotonin a cikin jini na jini na iya haifar da haɓaka mummunan hulɗa. A cikin lokuta mafi wuya, tare da yin amfani da magunguna na rage rage magungunan rage ruwa ® tare da SSRIs (magunguna don magance ciwon ciki), wasu kwayoyi don kula da cututtukan migraine (sumatriptan, dihydroergotamine), farfesa mai ƙarfi (pentazocine, pethidine, fentanyl) ko magungunan antitussive (dextromethorphan) na iya haɓaka. cutar serotonin.
Sibutramine baya tasiri sakamakon maganin hana daukar ciki.
Tare da gudanar da aikin kai-tsaye na sibutramine da barasa, babu karuwa a cikin mummunan tasirin barasa. Koyaya, ba a haɗuwa da giya tare da shawarar abinci na shawarar lokacin shan sibutramine.
Tare da amfani da wasu magunguna a lokaci guda tare da sibutramine wanda ke shafar hemostasis ko aikin platelet, haɗarin zub da jini yana ƙaruwa.
Harkokin hulɗa na miyagun ƙwayoyi tare da amfani da sibutramine na lokaci guda tare da kwayoyi waɗanda ke haɓaka hawan jini da bugun zuciya a halin yanzu ba a fahimta sosai. Wannan rukuni na kwayoyi sun hada da decongestants, maganin antitussive, sanyi da magungunan ƙwayar cuta, wanda ya haɗa da ephedrine ko pseudoephedrine. Saboda haka, a cikin halayen gudanar da magunguna lokaci guda tare da sibutramine, ya kamata a yi taka tsantsan. Haɗewar amfani da sibutramine tare da kwayoyi don rage nauyin jiki, aiki akan tsarin juyayi na tsakiya, ko magunguna don maganin cututtukan kwakwalwa sun haɗu.
Sashi da gudanarwa
A ciki Sau ɗaya a rana, da safe, ba tare da taunawa ba kuma shan sha da yawa (gilashin ruwa). Za'a iya ɗaukar miyagun ƙwayoyi duka a kan komai a ciki kuma a hade tare da abinci.
An saita kashi akayi daban-daban, gwargwadon haƙuri da ingancin asibiti. Matsakaicin farawa shine 10 MG / rana. Idan a cikin makonni 4 daga farkon jiyya, an sami raguwar nauyin jikin ƙasa da 2 kilogiram, to kashi yana ƙaruwa zuwa 15 MG / rana.
Xinarin kuzarin xinargin xinan ƙananan kada ya wuce fiye da watanni 3 a cikin marasa lafiya waɗanda ba su amsa da kyau don maganin, i.e. wanda a cikin watanni 3 na magani ya kasa cimma raguwa a cikin nauyin jikin mutum da 5% daga alamar farko. Bai kamata a ci gaba da jiyya ba idan, tare da ƙarin magani bayan an sami raguwar nauyin jiki, nauyin jikin mai haƙuri yana ƙaruwa da kilogiram 3 ko fiye.
Tsawon lokacin jiyya bai kamata ya wuce shekara 1 ba, tunda tsawon lokaci na ɗaukar mukamin sibutramine, ba a samun inganci da bayanan aminci.
Jiyya tare da Reduxine ® yakamata a gudanar dashi tare da abinci tare da motsa jiki a karkashin kulawar likita tare da kwarewar aiki a cikin magance kiba.
Yawan abin sama da ya kamata
Kwayar cutar akwai iyakantaccen shaida game da yawan yawan zubar da jini na sibutramine. Abubuwan da suka fi dacewa da rikice-rikice masu haɗari waɗanda ke da alaƙa da yawan ƙwayar cuta shine tachycardia, hauhawar jini, ciwon kai, farin ciki. Yakamata mara lafiya ya sanar da mai kula da lafiyarsa idan har ana zargin ya wuce haddi.
Jiyya: Babu takamaiman magani ko takamaiman maganin sha. Wajibi ne a aiwatar da matakan gabaɗaya: don tabbatar da numfashi kyauta, saka idanu yanayin CVS, kuma, idan ya cancanta, aiwatar da maganin warkewa. Gudanar da lokaci na carbon da aka kunna, har da lahani na ciki, na iya rage yawan narutramine a cikin jiki. Marasa lafiya da ke fama da cutar hawan jini da tachycardia an wajabta masu amfani da sinadarin beta. Ba'a tabbatar da tasiri na tilasta diuresis ko hemodialysis ba.
Umarni na musamman
Ya kamata a gudanar da jiyya tare da Reduxine ® a zaman wani yanki na hadaddun farke don asarar nauyi a karkashin kulawar likita tare da kwarewar aiki a cikin magance kiba.
Cikakken farji ya haɗa da canji a tsarin abinci da salon rayuwa, da kuma ƙaruwa cikin aiki na jiki.
Wani muhimmin bangaren aikin jiyya shine halittar abubuwan da ake bukata don samun canji mai daci a yanayin cin abinci, wanda ya zama dole don kula da rage girman lafiyar jiki koda bayan an dakatar da maganin magunguna. A matsayin wani ɓangare na ilmin likita tare da Reduxin ®, marassa lafiya suna buƙatar canza salon rayuwarsu da al'adunsu ta yadda bayan an kammala magani suna tabbatar da cewa an kiyaye girman rage girman jiki.
Marasa lafiya yakamata su fahimci cewa rashin cika waɗannan buƙatun zai haifar da karuwa a cikin nauyin jikin mutum da kuma maimaita ziyartar likitan halartar.
A cikin marasa lafiya suna shan Reduxin ®, ya wajaba don auna matakin hawan jini da raunin zuciya. A cikin watanni 3 na farko na magani, ya kamata a sa ido kan waɗannan sigogi kowane mako 2, sannan a kowane wata. Idan yayin ziyarar biyu a jere ana kara hauhawar zuciya a hutawa ≥10 beats / min ko CAD / DBP ≥10 mm Hg aka gano , dole ne a dakatar da magani. Marasa lafiya tare da hauhawar jini, a cikin sa, a cikin su, a bango na maganin rigakafin ƙwayar cuta, hawan jini ya fi ƙarfe 145/90 mm Hg. , wannan iko yakamata a gudanar dashi musamman a hankali kuma, idan ya zama dole, a takaice tazara. Marasa lafiya a cikin su wanda karfin jini sau biyu yayin maimaita shi ya wuce matakin 145/90 mm Hg. , magani tare da Reduxine ® yakamata a soke shi (duba. "Tasirin sakamako").
A cikin marasa lafiya da cututtukan tashin hankali na bacci, ya zama dole a lura da cutar hawan jini a hankali.
Musamman hankali yana buƙatar gudanar da kulawa ta lokaci guda na kwayoyi waɗanda ke haɓaka tazara QT. Wadannan kwayoyi sun hada da bloatamam H blockers.1masu karɓa (astemizole, terfenadine), magungunan antiarrhythmic waɗanda ke haɓaka tazara ta QT (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol), gastrointestinal motility stimulator cisapride, pimozide, sertindole da tricyclicpide. Wannan kuma ya shafi yanayin wanda zai iya haifar da karuwa a cikin tsaka-tsakin QT (hypokalemia da hypomagnesemia - duba “hulɗa”).
Tsarin dake tsakanin ciwan mai na MAO (wanda ya hada da furazolidone, procarbazine, selegiline) da xinaryar magani xin ya kamata ya zama awanni 2.
Kodayake ba a kafa haɗin tsakanin shan Reduxin ® da ci gaban hauhawar jini ba, amma, an ba da sananniyar haɗarin wannan rukuni na kwayoyi, tare da kulawar likita na yau da kullun, ya kamata a biya kulawa ta musamman ga alamura kamar ciwan dyspnea mai ci gaba (gazawar numfashi), ciwon kirji da kumburin kafafu. .
Idan kun tsallake kashi na xinar kuzarin xin, ya kamata ku sha kashi biyu na magani a kashi na gaba, ana bada shawara ku ci gaba da shan maganin gwargwadon lokacin da aka tsara.
Tsawon lokacin shan xinyarar xin kar ya wuce shekara 1.
Tare da amfani da sibutramine da sauran SSRIs, akwai haɗarin haɗarin zub da jini. A cikin marasa lafiya sun yi niyya ga zub da jini, kazalika da shan magungunan da ke shafar hemostasis ko aikin platelet, ya kamata a yi amfani da sibutramine tare da taka tsantsan.
Kodayake bayanan asibiti game da jaraba ga sibutramine basu kasance ba, yakamata a bincika ko akwai wasu maganganun dogaro da miyagun ƙwayoyi a tarihin mai haƙuri da kuma kula da alamun yiwuwar amfani da miyagun ƙwayoyi.
Sibutramine ya kasance daga cikin jerin abubuwan da ke da inganci, wanda Dokar Gwamnatin Tarayyar Rasha ta amince da ranar 29 ga Disamba, 2007 No. 964.
Tasiri kan iya tuka motoci da injinan. Reduaukar Refluine ® na iya iyakance iya ikon ku na tuƙi motoci da sarrafa injin. A lokacin amfani da miyagun ƙwayoyi na Reduarukar xin miyagun ƙwayoyi, dole ne a kula da duk lokacin da kake tuki motocin da kuma yin wasu ayyukan haɗari waɗanda ke buƙatar haɓakar haɓaka da saurin halayen psychomotor.
Mai masana'anta
LLC "Ozone". 445351, Russia, Yankin Samara, Zhigulevsk, ul. Sand, 11.
Tel./fax: (84862) 3-41-09.
Gwamnatin Tarayya mai zaman kanta Kamfanin “Endocrine Shuka ta Moscow”. 109052, Moscow, st. Novokhokhlovskaya, 25.
Tel./fax: (495) 678-00-50 / 911-42-10.
Adireshin da lambar tarho na ƙungiyar da aka ba da izini don lambobin sadarwa (gunaguni da korafi): LLC KYAUTA RUS. 105005, Russia, Moscow, ul. Malaya Pochtovaya, 2/2, p. 1, pom. 1, daki Na biyu.
Waya: (495) 640-25-28.
Hulɗa da ƙwayoyi
Erythromycin, ketoconazole da cyclosporine suna haɓakar ƙwayar plasma na sibutramine metabolites tare da karuwa a cikin zuciya da ƙara girman ƙarancin tsarukan QT.
Phenytoin, rifampicin, phenobarbital, carbamazepine, dexamethasone, da maganin rigakafin macrolide zasu iya haɓaka metabolism metabolism.
Tare da yin amfani da lokaci ɗaya tare da mitar nazari (pethidine, pentazocine, fentanyl), wasu magunguna don maganin migraine (dihydroergotamine, sumatriptan), magungunan antitussive (dextromethorphan) da magunguna don magance rashin jin daɗi, a cikin lokuta masu wuya, ci gaban cutar serotonin mai yiwuwa ne.
Ragewar kwayar cuta baya tasiri tasirin hana daukar ciki na baka.
Tare da gudanarwa na lokaci ɗaya tare da ethanol, ba a lura da karuwa a cikin mummunan tasirin ƙarshen ba. Koyaya, barasa bai dace da matakan abinci ba da shawarar lokacin jiyya.
Alamu don amfani
An wajabta rage rage nauyin don rage nauyi a cikin gaban waɗannan halaye masu zuwa:
- Yawan kiba a jiki tare da jigilar yawan jikin mutum (BMI) na 27 kg / m 2 ko sama da haka tare da sauran abubuwan haɗari waɗanda ke da alaƙa da nauyin kiba (rashin lafiyar insulin-insulin-insulin-delllius, dyslipoproteinemia),
- Yawan kiba tare da BMI na 30 kilogiram / m 2 ko fiye.
Umarnin don amfani da Reduxin: hanya da sashi
Ya kamata a sha kwayar cuta ta baki a baki sau ɗaya a rana, da safe, da haɗiye capsules gabaɗaya kuma shan su da isasshen ruwan sha, akan ciki mara wofi ko lokacin abinci.
Matsakaicin farawa shine 10 MG. Idan a cikin makonni 4 ba zai yiwu a cimma ragin rage girman nauyin jiki aƙalla 5% ba, ana ƙaruwa da kullun zuwa 15 MG.
Adadin jimlar magani bai wuce shekaru 2 ba (saboda karancin bayanai game da aminci da ingantaccen amfani da sibutramine).
Idan a cikin watanni 3 babu raguwa a cikin nauyin jikin mutum aƙalla 5% na nauyin farko, ana soke Choccin. Bai kamata a ci gaba da jiyya ba idan, tare da ƙarin gudanar da magani, mai haƙuri kuma ya ƙara kilogiram 3 ko fiye.