Yadda ake amfani da miyagun ƙwayoyi Ofloxin 200?
Akwai shi a cikin nau'ikan sashi daban-daban - mai kauri, ruwa, mai taushi. Yana da aikace-aikace iri-iri. Aiki mai aiki na kowane nau'i shine ofloxacin, quinolone na ƙarni na II.
Ofloxin 200 magani ne daga rukunin fluoroquinolones, babban wakilin maganin rigakafi.
An rufe da kuma dauke da wani daban-daban adadin aiki manufa. Ofloxin Allunan, ban da aiki na kwayan kwayoyi na ofloxacin (200 da 400 MG kowannensu), sun ƙunshi ƙarin waɗannan ƙarin abubuwan:
- madara sukari
- sitaci masara
- foda talcum
- hypromellose 2910/5.
Allunan an rufe su kuma suna dauke da wani daban-daban adadin aiki aiki.
Allunan sun bambanta a cikin sifa da ɗab'i suna nuna adadin babban abu (200 da 400 MG kowannensu). Kowane akwati yana dauke da tabar 1 1 dauke da allunan 10
Hannun kunne da na ido ana samun su. 1 ml na ingantaccen bayani ya ƙunshi:
- 3 MG naloxacin,
- bayani mai gishiri
- benzalkonium kolori,
- hydrogen chloride
- ruwa mai shirya.
Kunsasshen a cikin kwalban filastik tare da dropper.
Ofloxin 200 yana samuwa a cikin nau'in kunne da faɗuwar ido.
Ba shi da wannan nau'in sakin.
Maganin don jiko na launuka masu launin shuɗi-maraƙi ana cakuda su cikin 100 ml vials. Kwalban ya ƙunshi 200 MG na babban abu da kuma tsofaffi:
- bayani mai gishiri
- Trilon B
- hydrogen chloride
- ruwa mai shirya.
Rawaya gelatin kwalliya mai launin shuɗi mai launin ruwan kasa ya ƙunshi:
- Nauromacin - 200 MG,
- maganin
- sodium lauryl sulfate,
- madara sukari
- alli phosphate bisubstituted anhydrous,
- foda talcum.
Rawaya gelatin capsules an cakuɗe a cikin blister of 10 guda.
Ana cakuda capsules a blister of 10 guda.
Ana amfani da maganin a cikin nau'i mai laushi - maganin shafawa don magance raunuka (Oflokain) da kuma maganin shafawa ido don kwanciya a cikin jaka mai sanyi. Maganin shafawa an cakuda a cikin shambura na 15 ko 30 a cikin g 1 na samfurin ya ƙunshi:
- 1 MG naloxacin
- 30 mg lidocaine hydrochloride,
- prolylene glycol
- poloxamer
- macrogol 400, 1500, 6000.
Ana samar da maganin shafawa a cikin shagunan 3 da 5 g, wanda ya ƙunshi:
Ana amfani da maganin a cikin nau'i mai laushi - maganin shafawa don magance raunuka da maganin shafawa na ido don sanyawa a cikin jakar jigilar jaka.
Akwai wadatattun magungunan ƙwayar cuta a ƙarƙashin sunayen iri daban-daban.
Aikin magunguna
Abubuwan da ke tattare da kwayoyin cuta na Ofloxin 200 sune saboda hanawar kwayar halitta ta DNA-gyrase - enzymes da ke da alhakin hada kwayar halittar DNA a sel na kwayan cuta da kuma haifuwar su. Wadannan tsoffin enzymes suna da hannu cikin matakai biyu masu mahimmanci - karkacewa da tabbatar da kwanciyar hankali. Fluoroquinolone yana ba da gudummawa ga lalata ƙwayar ƙwayar cuta, sabili da haka, matakin haɗarin siffofin masu tsayayya suna da ƙasa.
Magungunan da suka fi aiki da ƙwayoyin cuta na gram. Batun Ofloxin 200 idan aka fallasa su topoisomerase II ne. Daga cikin rukuni na fluoroquinolones, miyagun ƙwayoyi sun shahara ga aikinta na musamman a kan cocci na gram. Manufarta ita ce topoisomerase IV.
Magungunan da suka fi aiki da ƙwayoyin cuta na gram.
Magungunan ƙwayoyin cuta na abu shine tushen lalata haɗin tsakanin helices na DNA (lalata shi), wanda ke haifar da mutuwar kwayar ƙwayar cuta. Irin wannan zaɓin ya haifar da shahararren ofloxacin da sauran fluoroquinolones - yawancin nau'ikan ƙwayoyin cuta masu tsayayya da sauran nau'ikan maganin rigakafi da sulfonamides suna ba da tasirin lalacewarsu.
Magungunan suna da ƙarancin adadin guba, as yana aiki ne kawai da kwayoyin halittar kwayar kwayar cuta, ba tare da lalata tsarin DNA na mutum ba. Sabili da haka, ana amfani da maganin a cikin aikin ilimin yara.
Pharmacokinetics
Magungunan suna cikin hanzari kuma ya ƙoshi cikin hanjinsa, har ya kai matakin da ya fi girma a cikin jini bayan sa'o'i 1-3. Abinci dan kadan yana hana tsarin sha, amma baya tasiri sosai. Magungunan yana da ɗayan digiri mafi girma na digestibility tsakanin fluoroquinolones - kusan 100%.
Magungunan suna cikin hanzari kuma ya ƙoshi cikin hanjinsa, har ya kai matakin da ya fi girma a cikin jini bayan sa'o'i 1-3.
Rabin rayuwarsa shine awanni 5-10, don haka ana iya shan magani sau 1-2 a rana. Mayar da hankali abu a cikin kyallen takarda daidai yake ko sama da tsinkaye. Idan ana gudanar da babban magani na magungunnan, to kayan sun tara a:
- Tsarin juyayi na tsakiya
- bututu na tagulla
- jakar articular
- tsarin urogenital
- a cikin sel na rigakafi.
Saboda waɗannan kaddarorin, miyagun ƙwayoyi suna da tasiri a cikin lura da kamuwa da cuta cikin jijiya. Ofloxacin yana yin karancin canji a jikin mutum - kashi 75 - 90% na kayan an cire su ba a cikin fitsari ba, wanda yake da mahimmanci a lura da cututtukan cututtukan da kodan da kansar hanji.
Abubuwan da ke gudana cikin jini na jini ba a ɗaure su da sunadarai ba kuma suna iya shiga cikin yardar rai daga gado na jijiyoyin jiki zuwa kyallen takarda.
Abubuwan da ke gudana cikin jini na jini ba a ɗaure su da sunadarai ba kuma suna iya shiga cikin yardar rai daga gado na jijiyoyin jiki zuwa kyallen takarda. Magungunan sun bambanta:
- tasiri a kowane pH
- Rashin tasiri a kan magunguna na methylxanthines,
- gaban wani sakamako postantibiotic,
- ƙananan abin da ya faru na dysbiosis,
- ingantaccen bayanin martaba.
Abin da ke ciki baya tasiri cikin jijiyar ciki da tayi bayan tayi.
Alamu don amfani
Aka nuna don kamuwa da cuta:
- tsarin urinary
- mace da gabobin maza,
- STI
- hanjin ciki
- tsarin biliary
- nosocomial da postoperative
- hanyoyin jirgin sama
- septicemia da bacteremia,
- Tsarin juyayi na tsakiya
- tarin fuka, kuturta.
Ofloxin 200 an nuna shi don magance cututtukan urinary tract.
Ofloxin 200 an nuna shi don magance cututtukan huhun hanji.
Ofloxin 200 an nuna shi don magance cututtukan ƙwayar cuta na maza.
Ana amfani da maganin shafawa don magance cututtukan fata, cututtukan hakori, da kuma kula da cututtukan da suka kamu.
Contraindications
Umarni a matsayin contraindication zuwa ga Ofloxin 200 yana nuna:
- yawan tashin hankali
- ciki da lactation
- far ga yara ‘yan kasa da shekaru 18,
- sankara da huhun ciki,
- kasancewar lalacewar tendon saboda amfanin fluoroquinolones,
- cytosolic rashi enzyme (G6FD).
Ofloxin 200 yana contraindicated idan akwai wani tashin hankali.
Ofloxin 200 yana contraindicated a cikin lactation.
Ofloxin 200 yana contraindicated a cikin yara a karkashin 18 shekara.
Tare da kulawa
A takaice dai an wajabta:
- maɓallin ƙwayoyin cuta,
- rikicewar Sistem a cikin kwakwalwa,
- mai aiki mai ɗaukar hoto,
- abnormalities na ci gaba da yanayin tsakiyar juyayi tsarin,
- bugun zuciya rashin nasara tare da tsawaita tazara ta QT.
An sake nazarin yawancin contraindications.
An yi taka tsantsan da magungunan don rikicewar cuta a cikin kwakwalwa.
An wajabta magani mai taka tsantsa don aikin nakasa mai rauni.
Ana nuna taka tsantsan don gazawar zuciya tare da tsawan tazara QT.
Yadda ake ɗaukar Ofloxin 200
An wajabta wa marasa lafiya manya 200-600 mg. Wannan tsawon lokacin shine 7-10 kwana. Za'a iya ɗaukar magani a cikin sashi na 400 MG sau ɗaya, zai fi dacewa da safe don rabin sa'a ko awa ɗaya kafin cin abinci, an rarraba babban kashi zuwa kashi 2. An ba da shawarar haɗiye allunan gaba ɗaya da ruwa. A cikin cututtukan da ke cikin raɗaɗi da kiba, ana ba da izinin ƙarin kashi har zuwa 800 MG / rana.
Idan cututtukan kumburi na ƙananan ƙwayar urinary (prostatitis, cystitis, urethritis) ba su da rikitarwa, to ya isa ya ɗauki 200 MG 1 sau ɗaya kowace rana don kwanaki 3-5. Don maganin cututtukan ƙwayar cuta, ana bada shawarar guda ɗaya na 400 MG.
Jigilar da tsarin kulawa a cikin marasa lafiya da gazawar koda ya dogara ne da yardawar Allah:
Cl creatine (ml / min.) | Yawan abu (mg) | Swing (sau ɗaya a rana) |
50-20 | 200 | 2 |
400 | 1 | |
Game da tsallakewar kashi
Idan mara lafiyar ya manta shan maganin, to an yarda ya sha shi da zaran mara lafiyar ya tuna da shi. Ana iya ɗaukar magani a cikin sashi na 400 MG sau ɗaya, zai fi dacewa da safe, rabin sa'a ko awa daya kafin cin abinci. Sakamakon sakamako na ofloxine 200An yarda da maganin sosai - halayen da ba su dace ba sun zama kashi 0,5% na lokuta. Koyaya, ana lura da sakamako masu illa a wasu lokuta. Marasa lafiya da ke fama da cutar sankarau yayin karatun tare da Ofloxin 200 suna buƙatar sarrafa glucose. Tsarin juyayi na tsakiyaA cikin nau'in rashin jin daɗi, damuwa, rashin bacci. Da wuya bayyana:
Daga tsarin kare jini
Daga fata, za'a iya samun rashes. Tasiri kan ikon sarrafa abubuwan injiHaramun ne a fitar da motocin kuma a yi aiki tare da hadaddun hanyoyin da ke buƙatar taro. Bayan shan maganin, haramun ne a fitar da motocin. Umarni na musammanM ga pathologies lalacewa ta hanyar pneumococci ko mycoplasmas - mashako na kullum, ciwon huhu, mashako. Idan akwai alamun rashin lafiyan, halayen da ba su dace ba daga tsarin juyayi na tsakiya, kuna buƙatar soke maganin.
Criptionaukar Ofloxin 200 yaraYara ba sa yin magani har sai girma da samuwar tsarin musculoskeletal ya cika. Koyaya, saboda dalilai na kiwon lafiya kuma a cikin rashin sakamako mai kyau ga sauran magungunan rigakafi, ana iya magance Ofloxin 200 a sikelin na 7.5 mg ta 1 kilogram na nauyin jiki. Matsakaicin izini shine 15 MG / kg. Yara ba sa yin magani har sai girma da samuwar tsarin musculoskeletal ya cika. Yi amfani da shi don aikin hanta mai rauniAna amfani da kayan aiki bisa kulawa ta yau da kullun game da adadin bilirubin, tare da karuwa, ana daidaita sakin ko soke wannan magani. Idan akwai aiki na hanta mai rauni, ana amfani da maganin ta hanyar saka idanu akai-akai na adadin bilirubin. Abubuwan haɗin gwiwaKada ayi amfani da lokaci ɗaya tare da:
Ba da shawarar haɗuwa baHaramun ne a hada shi da:
Haɗuwa yana buƙatar taka tsantsanAn bayar da rahoton lokuta na ƙara yawan aiki na maganin anticoagulants na baki tare da lura na lokaci daya tare da fluoroquinolones. Yayin shan magunguna waɗanda ke warware rukunin sinus, ya zama dole don sarrafa ECG. Ofloxin 200 bai dace da ethylate ba. Nazarin Ofloxin 200Ya samu kyakkyawan bita daga likitoci da kuma marasa lafiya. Maxim Alexandrovich, masanin ilimin uro, Minsk: "A duk lokacin da nake aikin likita na kasance ina amfani da fluoroquinolones a cikin lura da marassa lafiya. Ina ganin Ofloxin 200 zaiyi tasiri. Yana bada sakamako mai kyau kuma ana jure shi ba tare da wata illa ba." Galina Sergeyevna, likitan ilimin mahaifa, Kiev: "Mafi yawan lokuta ana bayar da umarnin Ofloxin 200 ga marasa lafiya da cutar kumburi. Yana da tsari mai dacewa, yana da kyau a sarrafa da kuma kiyaye sashi. Sauran magungunan rigakafi Lokacin da za a sha maganin rigakafi Olga, mai shekara 32, Kaluga: "An sha maganin ne yayin lura da cystitis. Na yi yawa. Bayan kwanaki da yawa na shan Ofloxin 200, alamu sun ɓace. Amma babu wasu sakamako masu illa, har ma da na al'ada bayan murkushe ƙwayoyin cuta." Mikhail, ɗan shekara 22, Omsk: "Na yi sanyi a wurin aiki, an gano matsaloli game da cutar urology. Likita ya ba da alluna 200 na Ofloxin - suna aiki da sauri. Sun taimaka da yawa." Tamara, mai shekara 40, Gorlovka: "Na sami mummunan gwaji don cututtukan bacci. A bisa shawarar likita, na dauki hanyar Ofloxin. Kwanan nan na sake komawa dakin gwaje-gwaje - sakamakon sakamako mara kyau ne. Komai na tafiya da sauri kuma ba tare da rikitarwa ba." |