Insulin protafan NM: siririn alkalami da bita

Don rage matakan glucose na jini, ana amfani da kwayoyi, mafi inganci daga cikinsu shine insulin. A cikin nau'in ciwon sukari na 1, lokacin da ƙwayar huhu ba ta iya samar da buƙatar wannan hormone ba, insulin ita ce hanya daya tilo don adana lafiyar da rayuwar marasa lafiya.

Ana gudanar da insulin sosai kamar yadda likita ya umarta kuma a ƙarƙashin sarrafa sukari na jini. Lissafin kashi ya dogara da abubuwan da ke tattare da carbohydrates a cikin abinci. An ƙayyade tsarin kulawa da akayi daban-daban ga kowane haƙuri kuma ya dogara da bayanin martaba na glycemic.

Don ƙirƙirar taro na insulin kusa da na halitta, ana amfani da gajeru, matsakaici da tsawan matakan aikin insulins. Matsakaiciyar matsakaiciyar sun hada da samfurin Novo Nordisk da kamfanin Danish ya kera - Protafan NM.

Fitar saki da kuma adana Protafan

Dakatarwar ta ƙunshi insulin - isophan, wato, insulin ɗan adam wanda aka samar da injiniyan kwayoyin.

A cikin 1 ml yana kunshe da 3.5 mg. Bugu da kari, akwai tsoffin abubuwan: zinc, glycerin, sulfate protamine, phenol da ruwa don yin allura.

An gabatar da insulin Protafan hm a cikin nau'i biyu:

Dakatarwa ga subcutaneous management na 100 IU / ml 10 ml a cikin vials an rufe shi da murfi na roba, mai rufi tare da alumomin gudu. Dole ne kwalban ya kasance da murfin filastik mai kariya. A cikin kunshin, ban da kwalban, akwai umarnin don amfani.
Protafan NM Penfill - a cikin gilashin gilashin hydrolytic, an rufe shi da diski na roba a gefe ɗaya da pistons na roba a ɗayan. Don sauƙaƙe haɗuwa, an dakatar da fitarwa tare da ƙwallon gilashi.
Kowane katun an hatimce a cikin takarda da za'a iya jefa Flexpen. Kunshin ya ƙunshi alkalami 5 da umarnin.

A cikin kwalba na 10 ml na Protafan insulin ya ƙunshi 1000 IU, kuma a cikin allon sikelin 3 ml - 300 IU. Lokacin tsayawa, an sanya fitowar zuwa cikin tsinkaye da ruwa mara launi, saboda haka dole ne a haɗu da abubuwan haɗin kafin amfani.

Don adana maganin, dole ne a sanya shi a kan shiryayyen tsakiyar firiji, zazzabi wanda ya kamata a kiyaye shi daga digiri 2 zuwa 8. Ka nisanci daskarewa. Idan an buɗe kwalban ko katangar Protafan NM Penfill, to, an adana shi a zazzabi a ɗakin, amma ba ya fi 25 ° C. Yin amfani da insulin Protafan dole ne a aiwatar dashi cikin makonni 6.

Ba a adana Flexpen a cikin firiji, zazzabi don kula da kaddarorinta na magunguna kada ta kasance sama da digiri 30. Don kariya daga haske, dole ne a sa hula a hannu. Dole ne a kiyaye abin hannu daga lalacewa da lalacewa ta inji.

An tsabtace shi daga waje tare da auduga swab da aka tsinke a cikin barasa, ba za a iya nutsar dashi cikin ruwa ko lubricated ba, saboda wannan ya keta tsarin. Kar a sake cika alkalami da aka sake amfani dashi.

An dakatar da dakatarwar da penlill a cikin katako ko alkalami ana bayar da su daga kantin magunguna ta hanyar takardar sayan magani.

Farashin insulin a cikin nau'in alkalami (Flexpen) ya wuce na Protafan NM Penfill. Mafi ƙarancin farashin dakatarwa a cikin kwalabe.

Yadda ake amfani da Protafan?

Ana gudanar da insulin Protafan NM ne kawai a ƙarƙashin ƙasa. Ba a bada shawarar gudanar da aikin jijiyoyin ciki da na ciki ba. Ba'a amfani dashi don cika famfan insulin. Tabbatar duba hula mai kariya lokacin siye a cikin kantin magani. Idan ba ya nan ko kwance, kar a yi amfani da insulin.

Ana ɗaukar magani ɗin da ba ta dace ba idan an keta yanayin ajiya ko ya daskarewa, kuma idan bayan haɗu ba ya zama mai yi daidai - fari ko girgije.

Gudun insulin na cikin ƙasa yana yin shi takamaiman tare da sirinji insulin ko alkalami. Lokacin amfani da sirinji, kuna buƙatar yin nazarin sikelin raka'a aiki. Sannan, ana jan iska zuwa cikin sirinji kafin a rarraba abubuwan da aka bada shawarar insulin. An bada shawara a mirgine murfin don motsawar dakatarwar da tafin hannuwanku. An gabatar da Protafan ne kawai bayan dakatarwar ta zama mai kama da juna.

Flexpen shine alkalami mai cika sirinji tare da ikon bayarwa daga raka'a 1 zuwa 60. Ana amfani dashi tare da NovoFayn ko NovoTvist needles. Tsawon allura shine 8 mm.

Yin amfani da alkairin sirinji ana aiwatar da shi bisa ka'idoji masu zuwa:

Duba tambarin da amincin sabon alkalami.
Kafin amfani, insulin yakamata ya kasance a zazzabi a daki.
Cire kwallan kuma matsar da rike sau 20 domin ƙwallon gilashi na iya motsawa tare da kicin.
Wajibi ne a haxa maganin don ya zama girgije a ko'ina.
Kafin allura ta gaba, kuna buƙatar motsa abin riƙewa sama da ƙasa aƙalla sau 10.

Bayan shirya dakatarwa, ana yin allurar nan da nan. Don ƙirƙirar dakatarwar uniform a cikin alkalami ya kamata ya zama ƙasa da 12 IU na insulin. Idan babu adadin da ake buƙata, to dole ne a yi amfani da sabon abu.

Don a haɗa allura, an cire sandar kariya kuma an aske allurar a alƙalin sirinji da ƙarfi. Sannan kuna buƙatar cire haɗin murfin waje, sannan na ciki.

Don hana kumfa iska daga shiga cikin allurar, buga lambobi 2 ta juyawa mai zaɓin kashi. Sannan nuna allura sama da matsa kwalin don sakin kumfa. Latsa maɓallin farawa gaba ɗaya, yayin da mai zaɓa ya koma sifili.

Idan digon insulin ya bayyana a ƙarshen allura, zaku iya yin allura. Idan babu digo, canza allura. Bayan canza allura sau shida, kuna buƙatar soke amfani da makullin, saboda yana da lahani.

Domin tabbatar da samarda sinadarin insulin, ya zama dole a bi irin wadannan ayyuka:

Selectan zaɓe an saita zuwa sifili.

Juya mai zabi a kowane bangare don zaɓar kashi ta haɗa shi tare da maɓallin. A wannan yanayin, ba za ku iya danna maɓallin farawa ba.
Takeauki fata a cikin shafawa ka saka allura a cikin gindin ta a kwana na 45.
Latsa maɓallin "Fara" har ya zuwa "0" ya bayyana.
Bayan an saka shi, allura ya kamata ya kasance karkashin fata na tsawon dakika 6 don samun dukkanin insulin. Lokacin cire allura, dole ne a riƙe maɓallin farawa a ƙasa.
Sanya hula a allura kuma bayan hakan za'a iya cire shi.

Ba'a ba da shawarar adana Flexpen tare da allura ba, tunda insulin na iya zubowa. Dole ne a zubar da allura da kyau, a guji allurar bazata. Duk sirinji da alkalami don amfanin kai kaɗai.

Mafi yawan shan insulin a hankali ana shigar da shi cikin fatar cinya, kuma hanya mafi sauri ta gudanarwa tana cikin ciki. Don allura, zaku iya zaɓar gluteus ko ƙarar fata mai ɗauka na kafada.

Dole a canza wurin yin allurar domin kada ya lalata kitsen mai ƙonawa.

Dalilin da sashi

Insulin ya fara aiki awoyi 1.5 bayan gamawa, ya kai matsakaici a cikin awanni 4-12, an kebe shi a cikin rana. Babban mahimmancin amfani da miyagun ƙwayoyi shine ciwon sukari.

Tsarin aikin hypoglycemic na Protafan yana da alaƙa da gudanar da glucose a cikin sel da kuma ƙarfafa glycolysis don makamashi. Insulin yana rage rushewar glycogen da samuwar glucose a cikin hanta. A ƙarƙashin rinjayar Protafan, ana adana glycogen a cikin ajiyar cikin tsokoki da hanta.

Protafan NM yana kunna aikin haɗin furotin da haɓaka, rarrabuwa a cikin sel, yana rage rushewar furotin, saboda wanda sakamakonsa yake nuna anabolic. Insulin yana shafar naman adipose, yana rage jinkirin mai da haɓaka ajiyarsa.

Ana amfani dashi galibi a cikin sauyawa don maganin cututtukan insulin-insulin na nau'in 1. Kasa da sau da yawa, an wajabta shi ga marasa lafiya na nau'in na biyu yayin ayyukan tiyata, haɗuwa da cututtukan cututtuka, yayin daukar ciki.

Ciki, kamar lactation, ba contraindication bane don amfanin wannan insulin. Ba ya ƙetare cikin mahaifa kuma ba zai iya isa ga jariri tare da madara ba. Amma yayin ciki da lactation, kuna buƙatar zaɓa a hankali kuma ku daidaita sashi koyaushe don kwantar da matakin glucose a cikin jini.

Ana iya tsara Protafan NM duka biyu daban-daban kuma a hade tare da insulin sauri ko gajere. Yawan yana dogara da matakin sukari da kuma hankali ga miyagun ƙwayoyi. Tare da kiba da balaga, a yawan zafin jiki yana sama. Hakanan yana kara buƙatar insulin a cikin cututtuka na tsarin endocrine.

Rashin isasshen ƙarfin, juriya na insulin ko watsi yana haifar da hyperglycemia tare da alamu masu zuwa:

Jin ya tashi.
Rashin rauni.
Cutar ciki ta zama mafi yawan lokuta.
Abun ci.
Kamshin acetone daga bakin.

Wadannan bayyanar cututtuka na iya ƙaruwa a cikin 'yan sa'o'i kaɗan, idan ba a rage sukari ba, to marasa lafiya na iya haɓaka ketoacidosis mai ciwon sukari, suna haifar da mummunan sakamako, musamman tare da ciwon sukari na 1.

Sakamakon sakamako na Protafan NM

Hypoglycemia, ko digo cikin sukari na jini, shine mafi tasirin sakamako masu haɗari na amfani da inulin. Yana faruwa tare da babban kashi, ƙaruwa ta jiki, abincin da aka rasa.

Lokacin da aka biya matakan sukari, alamun hypoglycemia na iya canzawa. Tare da tsawanta jiyya na ciwon sukari, marasa lafiya sun rasa ikonsu don gane farkon raguwar sukari. Magunguna da aka yi amfani da su don saukar da hawan jini, musamman waɗanda ba a zaɓi beta-blockers da kwantar da hankali ba, na iya canza alamun farko.

Sabili da haka, ana ba da shawarar akai-akai na matakan sukari, musamman a farkon makon amfani da Protafan NM ko lokacin da ake juyawa da shi daga wani insulin.

Na farko alamun ragewan sukari na jini a kasa na al'ada na iya zama:

Kwantar da hankali kwatsam, ciwon kai.
Jin damuwa, rashin damuwa.
Harin yunwa.
Haɗaɗɗa.
Remarfin hannu.
Saurin bugun zuciya da zafin zuciya.

A cikin mawuyacin yanayi, tare da hypoglycemia saboda rikice-rikice a cikin aikin kwakwalwa, disorientation, rikice-rikice ya haɓaka, wanda zai haifar da coma.

Don cire marasa lafiya daga hypoglycemia a cikin lokuta masu laushi, ana bada shawara don shan sukari, zuma ko glucose, ruwan 'ya'yan itace mai zaki. Idan hankalin mai rauni, 40% glucose da glucagon ana allurar dasu cikin jijiya. Don haka kuna buƙatar abinci dauke da carbohydrates mai sauƙi.

Tare da rashin haƙuri na insulin, halayen rashin lafiyan a cikin nau'in huhu, dermatitis, urticaria na iya faruwa, a lokuta mafi wuya ana girgiza anaphylactic. Abubuwan da ke haifar da sakamako na gefen farko a farkon jiyya za a iya bayyana su ta hanyar cin zarafin tunani da haɓakar retinopathy, kumburi, lalacewar ƙwayoyin jijiya a cikin nau'i mai raɗaɗi na neuropathy.

A cikin makon farko na maganin insulin, kumburi, sweating, ciwon kai, rashin bacci, tashin zuciya, da bugun zuciya na iya karuwa. Bayan samun amfani da miyagun ƙwayoyi, waɗannan alamun suna raguwa.

Zai iya zama kumburi, ƙaiƙayi, redness, ko birgewa a wurin allurar insulin.

Form sashi

Dakatar da ayyukan gwamnatin s / c na fararen launi, lokacin da aka daidaita shi, ya haifar da fararen farashi da launin kore ko kusan madaukakin launi, tare da motsa hankali, yakamata a sake tayar da hankali

isofan insulin (injiniyan ɗan adam) 100 IU *

Mahalarta: zinc chloride, glycerol, metacresol, phenol, sodium hydrogen phosphate dihydrate, sulfate protamine, hydrochloric acid da / ko sodium hydroxide bayani (don kula da pH), ruwa d / da.

* 1 IU yayi daidai da μg na 35 na insulin na mutum.

Pharmacodynamics

Protafan® NM Penfill® dakatarwa ce ta insulin mutum na rayuwa, wanda ya kunshi isofan-insulin.

Biosynthetic ɗan adam insulin an yi shi ne ta amfani da keɓaɓɓiyar fasahar DNA ta amfani da ƙwayoyin yisti a matsayin ƙwayar halitta mai samar da kwayoyin halitta. A miyagun ƙwayoyi ne mai monocomponent tsarkake insulin daidai yake ga insulin ɗan adam.

A cikin hannun riga na Penfill® takalmin gilashin ne wanda ke yin aiki don rarraba farin barbashin insulin. Lokacin da kuka juya Penfill sama da ƙasa sau da yawa, ruwan zai zama mara farin mara nauyi da kuma suttura.

Bayanin aiki na allurar subcutaneous (kimanin ƙididdiga):

fara aiki bayan sa'o'i 1.5, matsakaicin sakamako: daga 4 zuwa 12 hours, tsawon lokacin aiki: 24 awanni.

Siffofin Siyarwa

- ciwon sukari mai dogaro da insulin-insulin na sukari (nau'in I),

- rashin lafiyar insulin-dogara da ciwon sukari mellitus (nau'in II): mataki na jure wa bakin mahaifa na bakin jini, juriya ga wadannan kwayoyi (yayin hawan maganin), cututtukan da ke addabar ciki, aiki, ciki

Hulɗa da ƙwayoyi

Akwai magunguna da yawa waɗanda ke shafar buƙatar insulin. Sabili da haka, idan kuna shan magunguna, nemi likita.

Kuna iya siyan Protafan nm penfill 100me / ml 3ml n5 kabad a Moscow a cikin kantin magani mafi dacewa a gareku ta sanya oda akan Apteka.RU.
Farashin kayan kwalliya na Protafan nm penfill 100me / ml 3ml n5 kwantena a cikin Moscow shine 800,00 rubles.
Umarnin don amfani da kundin katako na Protafan nm 100me / ml 3ml n5.

Kuna iya ganin wuraren bayarwa mafi kusa a Moscow anan.

Farashi don Protafan Nm a wasu biranen

Ana saita yawan maganin a likitance daban-daban a kowane yanayi. Ana amfani da miyagun ƙwayoyi don allurar subcutaneous. Bayan allura, allura ya kamata ya kasance ƙarƙashin fata na daƙiƙaƙi kaɗan, wanda ke tabbatar da cikakken kashi.

Game da ciwon sukari-wanda ke dogara da ciwon sukari mellitus (nau'in I), ana amfani da miyagun ƙwayoyi azaman basal insulin tare da shiri insulin mai sauri.

Tare da mellitus-non-insulin-dogara da ciwon sukari mellitus (nau'in II), za a iya amfani da miyagun ƙwayoyi a matsayin monotherapy kuma a hade tare da insulins masu aiki da sauri.

Lokacin canja wurin mai haƙuri daga ingantaccen alade ko insulin ɗan adam zuwa Protafan NM Penfill, yawan maganin yana kasancewa iri ɗaya.

Lokacin canja wurin daga naman sa ko hadewar insulin zuwa Protafan NM Penfill, yakamata a rage kashi 10%, sai dai in farkon kashi ya kasance ƙasa da 0.6 U / kg nauyin jiki.

A cikin adadin yau da kullun wanda ya wuce 0.6 U / kg, dole ne a gudanar da insulin a cikin nau'in 2 ko fiye da injections a wurare daban-daban

Abun Harkokin Magunguna

Gudanar da magunguna a lokaci guda na iya inganta sakamakon insulin. Waɗannan sun haɗa da inhibitors na monoamine oxidase (Pyrazidol, Moclobemide, Silegilin), magungunan antihypertensive: Enap, Kapoten, Lisinopril, Ramipril.

Hakanan, yin amfani da bromocriptine, steroids anabolic, Colfibrate, Ketoconazole da Vitamin B6 suna kara haɗarin haɗarin hypoglycemia tare da ilimin insulin.

Magungunan cututtukan ciki suna da tasirin haka: glucocorticosteroids, hormones thyroid, maganin hana haihuwa, maganin tricyclic antidepressants da thiazide diuretics.

Ana iya buƙatar haɓakar kashi na insulin lokacin da yake tsara Heparin, allunan tashar alli, Danazole da Clonidine Bidiyo a wannan labarin zai ƙara samar da bayanai game da insulin instofan.

Protafan insulin: bayanin, kwalliya, farashi

Insulin Protafan yana nufin matsakaiciyar insulin-ɗan adam.

Bukatar amfani da miyagun ƙwayoyi Insulin Protafan HM Penfill na iya faruwa tare da cututtuka da yanayi da yawa. Da farko dai, tare da nau'in 1 da nau'in ciwon sukari na 2. Bugu da ƙari, ana nuna magungunan a mataki na jure magunguna na farko da aka fara amfani da su.

Hakanan ana amfani da miyagun ƙwayoyi tare da haɗin magani (wani ɓangaren rigakafi don maganin cututtukan baki), idan aka kamu da cutar sankara a cikin mata masu ciki kuma idan maganin rashin abinci ya taimaka.

Cutar cututtukan ciki da gudummawar tiyata (hade ko monotherapy) na iya zama dalilin saduwa.

Siffofin magani

Magungunan shine dakatarwar da aka gabatar a karkashin fata.

Kungiya, abu mai aiki:

Isulin insulin-semisynthetis mutum (semisynthetic human). Yana da matsakaita tsawon lokacin aiki.Protafan NM yana contraindicated a cikin: insulinoma, hypoglycemia da hypersensitivity ga aiki abu.

Yadda za a ɗauka kuma a cikin wane sashi?

Inulin yana allura sau ɗaya ko sau biyu a rana, rabin sa'a kafin cin abinci safe. A wannan yanayin, inda za a yi allura, koyaushe ya kamata a canza shi.

Ya kamata a zaɓi kashi don kowane mai haƙuri daban-daban. Yawanta ya dogara da adadin glucose a cikin fitsari da kwararar jini, da kuma sifofin halayen cutar. M, ana wajabta maganin sau 1 a kowace rana kuma shine 8-24 IU.

A cikin yara da tsofaffi masu laushi zuwa insulin, an rage girman kashi zuwa 8 IU kowace rana. Kuma ga marasa lafiya da ƙarancin hankali, likitan da ke halartar na iya tsara adadin da ya wuce 24 IU kowace rana. Idan kashi na yau da kullun ya wuce 0.6 IU a kowace kilo, to, ana gudanar da maganin ta hanyar allura biyu, waɗanda ake yi a wurare daban-daban.

Marasa lafiya da ke karɓar IU 100 ko fiye da kowace rana, lokacin da ake canza insulin, dole ne a koyaushe a ƙarƙashin kulawar likitoci. Sauya magungunan tare da wani ya kamata a gudanar dashi tare da kula da matakan glucose na jini koyaushe.

Kayan magunguna

Kayan aikin insulin Protafan:

lowers matakan glucose jini,
yana inganta ciwan glucose a cikin kyallen takarda,
Yana ba da gudummawa ga ingantaccen tsarin furotin,
lowers cikin adadin kuzari na hanta,
haɓaka glycogenogenesis,
inganta lipogenesis.

Microinteraction tare da masu karɓa a cikin sel membrane na haɓaka samuwar hadaddun mai karɓar insulin. Ta hanyar motsawa a cikin ƙwayoyin hanta da ƙwayoyin mai, aikin sansanin ko shigarwar shiga cikin tsoka ko ƙwayar rai, ƙwaƙwalwar mai ɗaukar insulin ɗin tana kunna ayyukan da ke faruwa a cikin sel.

Hakanan yana fara haɗarin wasu mahimman enzymes (glycogen synthetase, hexokinase, pyruvate kinase, da sauransu).

Rage glucose na jini yana faruwa ne ta:

transportara yawan jigilar glucose a cikin sel,
kara kuzari na glycogenogenesis da lipogenesis,
ptionarin yawan sha da sikari na glucose ta kyallen,
sunadaran gina jiki
raguwa a cikin yawan samar da sukari ta hanta, i.e. raguwa cikin rushewar glycogen da sauransu.

Side effects

Hypoglycemia (rashin hangen nesa da magana, pallor na fata, rikicewar motsi, karuwar gumi, hali mai ban tsoro, bugun kirji, tashin hankali, rawar jiki, rashin jin daɗi, haɓakar abinci, tsoro, tashin hankali, rashin bacci, tashin hankali, matsananciyar damuwa, bacci a bakin, ciwon kai ,

Allergic halayen (rage karfin jini, urticaria, gazawar numfashi, zazzabi, angioedema),

Increasearin haɓaka cikin kayan ƙirar rigakafin ƙwayar insulin tare da ƙarin karuwa a cikin glycemia,

Acidosis da ciwon sukari (hyperglycemia) (a bango na kamuwa da cuta da zazzabi, karancin abinci, allurar da aka rasa, allurai kadan): zubar da fuska, kwanciyar hankali, rashin ci, rashin ruwa a koda yaushe,

A matakin farko na farji - kurakurai masu narkewa da edema (sabon abu ne na ɗan lokaci wanda ke faruwa tare da ƙarin magani),

Rashin sani (wani lokacin coma da precoatose jihar tasowa),

A wurin allurar, itching, hyperemia, lipodystrophy (hauhawar jini ko atrophy na kitse subcutaneous),

A farkon magani cuta ce ta wucin gadi na gani,

Abubuwan da suka shafi rigakafi tare da insulin mutum.

katsewa
gumi
cutar rashin daidaituwa
bugun zuciya
rashin bacci
gurguwar gani da magana,
rawar jiki
tangled motsi
nutsuwa
karuwar ci
bakon hali
damuwa
haushi
paresthesia a cikin bakin ciki,
bacin rai
pallor
tsoro
ciwon kai.

Ta yaya za mu bi da yawan abin sama da ya kamata?

Idan mai haƙuri yana cikin yanayin hankali, to likita ya tsara dextrose, wanda aka gudanar ta hanyar dropper, intramuscularly ko intravenously. Hakanan ana gudanar da Glucagon ko kuma maganin rage karfin hypertonic dextrose.

Game da haɓakar ƙwayar cuta na haila, 20 zuwa 40 ml, i.e. Maganin 40% na dextrose har sai mara lafiyar ya fito daga mahaifa.

Kafin ku ɗauki insulin daga kunshin, kuna buƙatar bincika cewa mafita a cikin kwalbar tana da launi mai launi. Idan girgije, hazo ko gawar kasashen waje suna bayyane, mafita haramun ne.
Zazzabi na miyagun ƙwayoyi kafin gudanarwa ya kamata ya zama zazzabi dakin
A gaban cututtukan cututtuka, rashin aiki na glandar thyroid, cutar Addiosn, rashin lafiyar koda, rashin lafiyar jiki, da masu ciwon sukari na tsufa, ana buƙatar daidaita insulin daban-daban.

Sanadin cututtukan hypoglycemia na iya zama:

yawan abin sama da ya kamata
amai
canjin magani
cututtukan da ke rage buƙatar insulin (cututtukan hanta da koda, hauhawar cututtukan ƙwayar thyroid, glandon ƙwayar ƙwayar ciki, hanji mai ciki),
rashin kiyaye tsarin abinci,
hulɗa tare da wasu kwayoyi
zawo
kangin aiki,
canjin wurin allura.

Lokacin canja mai haƙuri daga insulin dabba zuwa insulin ɗan adam, rage raguwar glucose jini na iya bayyana. Canjin zuwa insulin mutum ya zama barata daga mahangar likitanci, kuma yakamata a gudanar dashi karkashin tsananin kulawa da likita.

Lokacin haihuwa da bayan haihuwa, za a iya rage yawan buƙatar insulin sosai. Yayin shayarwa, kuna buƙatar saka idanu akan mahaifiyarku tsawon watanni, har sai an daidaita buƙatar insulin.

Abun da ke faruwa game da ci gaban hawan jini na iya haifar da lalacewa a cikin ikon mara lafiya ya tuƙi motoci da kuma kula da injuna da injin.

Tare da taimakon sukari ko abinci tare da babban abun ciki na carbohydrates, masu ciwon sukari na iya dakatar da nau'in hypoglycemia mai laushi. A bu mai kyau cewa mai haƙuri koyaushe yana da akalla 20 g na sukari tare da shi.

Idan an jinkirta hypoglycemia, ya zama dole a sanar da likita wanda zaiyi gyaran jiyya.

Yayin cikin ciki, raguwa (1 trimester) ko haɓaka (2-3 na uku) na buƙatar jikin insulin ya kamata a la'akari.

Yin hulɗa tare da wasu kwayoyi

MAO inhibitors (selegiline, furazolidone, procarbazine),
sulfonamides (sulfonamides, magungunan baka na hawan jini),
NSAIDs, ACE inhibitors da salicylates,
magungunan anabolic steroids da methandrostenolone, stanozolol, oxandrolone,
carbonic anhydrase inhibitors,
ethanol
androgens
chloroquine
bromocriptine
quinine
karafasukas
quinidine
shiryawa
pyridoxine
ketoconazole,
Li + shirye-shirye,
mebendazole,
akarijin
fenfluramine,
karafarini.

H1 blockers - masu karɓa na bitamin,
glucagon,
epinephrine
somatropin,
phenytoin
GKS,
nicotine
maganin hana haihuwa
marijuana
estrogens
ƙwayar cuta
madaukai,
diazoxide
BMKK,
masu maganin tashin zuciya
hodar iblis,
clonidine
heparin
tricyclic maganin rigakafin,
sulfinpyrazone
danazol
tausayawa.

Hakanan akwai magunguna waɗanda zasu iya raunana biyu da haɓaka tasirin insulin. Wadannan sun hada da:

pentamidine
beta hanawa,
octreotide
madarar ruwa.

Protafan nm penfill - umarnin don amfani, farashi, sake dubawa da kuma alamun analogues

Protafan NM Penfill wakili ne na warkewa wanda aikinsa yana da nasaba da kula da masu ciwon sukari. Magungunan, lokacin amfani dashi daidai, yana ba ku damar bin matakin da ake buƙata na glucose a cikin jini, ba tare da cutar da lafiyar mai haƙuri ba.

Sunan kasa da kasa mai zaman kansa

A.10.A.C - insulins da kwatankwacinsu tare da matsakaicin lokacin aiki.

Dakatarwa don subcutaneous management na 100 IU ml ana samun su ta hanyar: kwalban (10 ml), kabad (3 ml).

Tsarin 1 ml na miyagun ƙwayoyi ya ƙunshi:

Abubuwan da ke aiki: insulin-isophan 100 IU (3.5 mg).
Abubuwa masu taimako: glycerol (16 mg), zinc chloride (33 μg), phenol (0.65 mg), sodium hydrogen phosphate dihydrate (2.4 mg), protamine sulfate (0.35 mg), sodium hydroxide (0.4 mg) ), metacresol (1.5 MG), ruwa don yin allura (1 ml).

Dakatarwa don subcutaneous management na 100 IU ml ana samun su ta hanyar: kwalban (10 ml), kabad (3 ml).

Aikin magunguna

Yana nufin jami'in hypoglycemic yana da matsakaicin tsawon lokacin aiki. An samar dashi ta hanyar fasahar DNA ta sake amfani da fasaha ta amfani da Saccharomyces cerevisiae. Yana hulɗa tare da masu karɓar membrane, samar da hadaddun insulin-receptor wanda ke inganta haɓakar enzymes da ke rayuwa (hexokinases, glycogen synthetases).

Magungunan yana motsa jigilar sunadarai ta hanyar sel. Sakamakon haka, haɓaka tasirin glucose yana inganta, ana inganta lipo- da glycogenesis, kuma haɓakar glucose ta hanta yana raguwa. Bugu da ƙari, ana kunna aikin furotin.

Pharmacokinetics

Ingantaccen ƙwayar da saurin tsabarta yana ƙaddara ta sashi, wurin gudanarwa, hanyar allura (subcutaneous, intramuscular), abun cikin insulin a cikin magunguna. Matsakaicin abun ciki na abubuwanda aka sanya cikin jini ana kai shi ne bayan sa'o'i 3 zuwa 16 bayan allura.

Yadda ake ɗaukar Protafan NM Penfill?

Yi allurar ciki ko subcutaneous allura. An zabi sashi yana la'akari da ƙayyadaddu da halayen cutar. Yawan halatta na insulin ya bambanta tsakanin 0.3-1 IU / kg / rana.

Inulin ya allura da allura ta syringe. Mutanen da ke da juriya na insulin suna ƙaruwa da buƙatar insulin (a lokacin haɓaka jima'i, nauyin jikin mutum ya wuce kima), don haka an umurce su da matsakaicin adadin.

Don rage haɗarin lipodystrophy, ya wajaba don maye gurbin wurin gudanar da maganin. Dakatarwa, bisa ga umarnin, an hana shi sosai shiga ciki.

Tare da ciwon sukari

Ana amfani da Protafan ga kowane nau'in ciwon sukari. Aikin warkewa yana farawa ne da nau'in ciwon suga guda 1. An tsara nau'in magani na 2 idan babu wani sakamako daga abubuwan ƙayyadaddun sulfonylurea, a lokacin daukar ciki, lokacin da bayan tiyata, tare da rakiyar cututtukan da ke da tasirin gaske a kan cutar sankara.

Sakamakon sakamako na Protafan NI Penfill

Abubuwan da ke faruwa mara kyau da aka lura a cikin marasa lafiya a lokacin warkewar hanya suna faruwa ne ta hanyar jaraba kuma suna da alaƙa da aikin magunguna na miyagun ƙwayoyi. Daga cikin mawuyacin halayen da ake fama da su, an lura da cutar hypoglycemia. Yana bayyana sakamakon rashin bin ka'idojin insulin.

A cikin matsanancin rashin ƙarfi, rashin hankali, rashi, aikin kwakwalwa mai rauni, da kuma wani lokacin mutuwa, mai yiwuwa ne. A wasu halaye, akwai take hakkin metabolism na metabolism.

A bangare na rigakafi na iya yiwuwa: kurji, urtikaria, sweating, itching, karancin numfashi, rudani na zuciya, rage karfin jini, raunin hankali.

A wani ɓangare na rigakafi, mummunan sakamako mai yiwuwa ne: kurji, urticaria, itching.

Tsarin juyayi shima yana cikin haɗari. A cikin mafi yawan lokuta, yanki na farji yana faruwa.

Umarni na musamman

Selectedaran da aka zaɓa ba bisa ƙa'ida ba ko kuma dakatar da jijiyoyin jiki yana haifar da cutar hauka. Alamar farko fara bayyana ne a cikin 'yan awanni ko kuma kwanaki. Idan ba a ba da taimako akan lokaci ba, hadarin kamuwa da cutar ketoacidosis, wanda ke cutar da rayuwar mutum yana ƙaruwa.

Tare da concomitant pathologies waɗanda ke bayyana ta zazzabi ko kamuwa da cuta, buƙatar insulin a cikin marasa lafiya yana ƙaruwa. Idan ya cancanta, canza sashi za'a iya gyara shi a lokacin allurar farko ko tare da ƙarin magani.

Yi amfani da tsufa

Marasa lafiya har zuwa shekara 65 ba su da ƙuntatawa kan shan maganin. Bayan sun kai wannan zamani, marassa lafiya yakamata su kasance karkashin kulawar likita kuma suyi la’akari da abubuwan da suka shafi hakan.

Ana iya amfani dashi don yara 'yan ƙasa da shekara 18. An kafa sashi daban-daban kan binciken. Mafi sau da yawa ana amfani dashi a cikin nau'in diluted.

Yi amfani da lokacin daukar ciki da lactation

Anyi amfani dashi yayin daukar ciki, as bai ƙetare mahaifa ba. Idan ba a kula da cutar sankara ba a lokacin lokacin haihuwa, hadarin zuwa tayi yana ƙaruwa.

Rikicewar ƙwayar cuta yana faruwa tare da hanyar da ba a zaɓa ba ta hanyar magani, wanda ke kara haɗarin lahani ga yaro kuma ya yi masa barazanar mutuwa ciki. A cikin watanni na farko, buƙatar insulin ya ragu, kuma a cikin 2 da 3 yana ƙaruwa. Bayan bayarwa, buƙatar insulin ya zama iri ɗaya.

Magungunan ba shi da haɗari lokacin shayarwa. A wasu yanayi, ana buƙatar yin gyare-gyare ga tsarin allura ko abinci.

Doaukar hoto na Protafan NI Penfill

Ba'a gano allurai masu haifar da yawan zubar da ciki ba. Ga kowane mai haƙuri, yin la'akari da ƙayyadaddun hanyoyin cutar, akwai babban kashi, wanda ke haifar da bayyanar cututtukan hyperglycemia.

Tare da yanayi mai laushi na hypoglycemia, mai haƙuri zai iya jure shi da kansa ta hanyar cin abinci mai daɗi da abinci mai ɗauke da ƙwayoyin carbohydrates mai yawa.

Ba shi da matsala a koyaushe a kan kayan lefe na hannu, kukis, ruwan 'ya'yan itace ko kuma sukari kawai.

A cikin siffofin masu tsanani (rashin sani), maganin glucose (40%) an allura a cikin jijiya, 0.5-1 mg na glucagon karkashin fata ko tsoka. Lokacin da aka kawo mutum hankali, don kauce wa hadarin maimaitawa, sukan ba da abinci mai-carb.

Yanayin ajiya na miyagun ƙwayoyi

Dole ne a adana magungunan a cikin sanyi da wuri mai duhu a zazzabi na + 2 ... + 8 ° C (ana iya sanya shi a cikin firiji, amma ba firiji). Ba batun daskarewa bane. Dole ne a ajiye katun a cikin kayan kwalliyar don kare ta daga hasken rana.

An adana katako wanda aka buɗe a cikin 30 ° C bai wuce kwanaki 7 ba. Kada a ajiye a firiji. Hana yara damar shiga.

Mai masana'anta

NOVO NORDISK, A / S, Denmark

Protafan insulin: bayanin, kwalliya, farashi

Logan adam insulin Protafan

Svetlana, dan shekara 32, Nizhny Novgorod: “A lokacin daukar ciki na yi amfani da Levemir, amma yawan haihuwar jini ya bayyana a koyaushe. Likitan da ke halartar ya ba da shawarar canzawa zuwa allurar Protafan NM Penfill. Halin ya inganta, sakamako masu illa a cikin ciki kuma bayan ba a lura da su ba. "

Konstantin, dan shekara 47, Voronezh: “Shekaru 10 kenan yanzu na kamu da ciwon sukari. Duk tsawon lokacin ban iya zaɓar wa kaina magani mai dacewa don riƙe glucose a cikin jini ba. Watanni shida da suka wuce kawai na sayi allurar Protafan NM Penfill injections kuma na gamsu da sakamakon. Duk wahaloli da rikice-rikice waɗanda suka bayyana a baya ba su sake jin kansu ba kuma. Farashin mai araha. "

Valeria, shekara 25, St. Petersburg: “Na yi rashin lafiya da ciwon sukari tun ina ƙuruciya. Na gwada fiye da 7 kwayoyi, kuma ba daya gamsu. Magunguna na ƙarshe da na saya kamar yadda likitan na umurce ni shine dakatar da Protafan NM Penfill.

Har zuwa kwanan nan, Na yi shakkar ingancinsa kuma ban fata musamman cewa yanayin zai canza ba. Amma ta lura cewa bayyanar hypoglycemia ya daina damuwa, yanayin lafiyar gaba ɗaya al'ada. Ina siyan a cikin kwalabe.

Samfurin ya dace don amfani kuma ba shi da tsada. ”

Protafan - cikakkun bayanai don amfani

Ciwon sukari mellitus yana nufin cututtukan cututtukan daji waɗanda ke shafar duk gabobin. Hanyar asali na haɓaka yana haɗuwa da rashi na insulin na hormone, wanda ke da alhakin amfani da glucose ta sel. Sakamakon haka, akwai rashin daidaituwa a cikin metabolism, matakin glucose a cikin jini ya hau. Maganin cutar sankarar mellitus na narkewa zuwa sauyawa na kwaya ta tsawon rayuwa.

An samar da dukkanin layi na wucin gadi. Ofayansu shi ne Protafan. Umarnin don amfani ya ƙunshi cikakkun bayanai da suka wajaba don amfanin mai amfani da wannan magani mai mahimmanci.

Abun ciki da nau'i na saki

Abubuwan da ke aiki shine insulin ɗan adam, wanda ke tattare da fasahar injiniyan kwayoyin. Akwai shi da yawa sashi siffofin:

"Protafan NM": wannan dakatarwa ce a cikin vials, kowane 10 ml, insulin taro na 100 IU / ml. Kunshin ya ƙunshi kwalban 1.
Protafan NM Penfill: katukanda ke dauke da 3 ml (100 IU / ml) kowannensu. A cikin ɗayan lamiri guda daya - harsashi 5, a cikin kunshin - 1 blister.

Mahalarta: ruwa don allura, glycerin (glycerol), phenol, sodium hydrogen phosphate dihydrate, sulfate protamine, metacresol, sodium hydroxide da / ko hydrochloric acid (don daidaita pH), zinc chloride.

Ciplesa'idojin yin amfani da Protafan

Ana amfani da maganin don kowane nau'in ciwon sukari. A nau'in I, ana fara magani kai tsaye tare da shi, a cikin nau'in II, ana nuna Protafan a cikin maganganun rashin ƙarfi na abubuwan da suka haifar na sulfonylurea, lokacin daukar ciki, lokacin da bayan aiwatarwa, a gaban cututtukan haɗin gwiwa da ke rikita yanayin ciwon sukari.

Clinical Pharmacology

An fara aikin aikin 1.5 hours bayan subcutaneous management. Ingantaccen aiki - bayan awoyi 4-12. Matsakaicin tsawon aiki shine awoyi 24.

Irin waɗannan magungunan likita suna ƙayyade babban ka'idodin amfani da "Protafan":

Mellitus-insulin-dogara da ciwon sukari mellitus - azaman kayan aiki na asali a haɗe tare da insulins-gajere.
Mellitus-non-insulin-dogara da ciwon sukari mellitus - monotherapy tare da wannan wakili an yarda, kazalika da haɗuwa tare da kwayoyi masu saurin aiki.

Idan ana amfani da magani azaman magani na mono, ana saka farashi kafin abinci. A cikin amfani na asali, ana gudanar da shi sau ɗaya a rana (safe ko maraice).

Tambayar ko za a iya ba da Protafan da yawanci yana da amsa mara kyau; wannan koyaushe shine tushen maganin cutar da ba'a iya rarraba ta ba.

Hanyar aikace-aikace

Magungunan yana allurar fata. Matsayi na gargajiya shine yankin hip. An yarda da allura a cikin yankin bango na ciki, gindi, da kuma tsoka a hannu. Dole ne a canza wurin da allurar don hana ci gaban lipodystrophy. Wajibi ne a cire fatar fatar don hana ci gaba cikin insulin.

MUHIMMIYA! Gudun cikin insulin da shirye-shiryensa haramun ne a kowane yanayi.

Hanyar amfani da alkairin sirinji don insulin "Protafan"

Gudanar da kai na dogon lokaci na siffofin allura yana buƙatar sauƙaƙe wannan hanyar gwargwadon iko. A saboda wannan, an haɗu da yaren syringe, wanda aka farfado tare da katako na Protafana.

Kowane mai haƙuri da ciwon sukari ya kamata ya san umarnin don amfani ta zuciya:

Kafin a cika kicin ɗin, duba marufin don tabbatar da cewa matakin daidai ne.
Tabbatar bincika katun da kansa: idan akwai wani lahani a cikin shi ko an gano sarari tsakanin farin tef ɗin da pistin na roba, to ba a amfani da wannan fakitin.
Ana kula da membrane na roba tare da mai maganin maye ta amfani da swab na auduga.
Kafin shigar da katun, an tsabtace tsarin. Don yin wannan, canza wuri saboda ƙwallon gilashi a ciki ya motsa daga wannan ƙarshen zuwa wancan akalla aƙalla 20. Bayan wannan, ya kamata ruwan ya zama mai ɗaukar hoto.
Kawai waɗannan katunan da ke ɗauke da aƙalla raka'a insulin guda 12 suna buƙatar haɗawa bisa ga hanyar da aka bayyana a sama. Wannan shine mafi ƙarancin adadin don cikawa cikin alkalami mai sirinji.
Bayan an saka shi a karkashin fata, allura ya kamata ya kasance a can a kalla 6 seconds. A wannan yanayin kawai za'a shigar da kashi gaba daya.
Bayan kowace allura, an cire allura daga sirinji. Wannan yana hana yaduwar ruwan da ba'a sarrafa shi ba, yana haifar da canji a cikin ragowar sashi.

Protafan: umarnin don amfani, farashi, sake dubawa da kuma alamun analogues

Akwai magunguna da yawa akan kasuwar magunguna waɗanda kamfanonin magunguna ke samarwa, amma samin mafi kyawu ga kowane mai haƙuri da ciwon sukari yana da matukar wahala. Dangane da umarnin don amfani, "Protafan NM" yana da kyawawan kaddarorin kuma yana da araha. Yi la'akari da wannan magani a cikin ƙarin daki-daki.

Tsarin saki, abun da aka shirya da marufi

Magungunan farin dakatarwa ne. Lokacin da aka adana, sai ya zama ruwa mara launi tare da farin tsinkaye. Wannan ba yana nufin cewa miyagun ƙwayoyi sun lalace ba - tare da girgizawa, dakatarwar ta koma yanayin da ta gabata.

insulin-isophan a taro na 100 IU a 1 ml,
zinc chloride
glycerin (glycerol),
metacresol
phenol
sodium hydrogen phosphate foda,
furotin sulfate,
sodium hydroxide da / ko hydrochloric acid,
ruwa don yin allura.

Akwai shi a cikin kundin kayan (guda 5 a kowane fakitin) ko a cikin 10 ml vials.

INN masana'antun

Sunan kasa-da-kasa wanda ba na mallakar sa ba shine insulin-isophan (injiniyan dan adam).

Kamfanin Novo Nordisk, Bugswerd, Denmark ne suka ƙera. Akwai ofishin wakilci a Rasha.

Ya bambanta daga 400 rubles (ga kwalban 10 ml) zuwa 900 rubles (don katako). Za'a iya samun kantin magani na kan layi akan ƙananan farashi.

nau'in 1 da nau'in ciwon sukari na 2
nau'in ciwon sukari na 2 a cikin mata masu juna biyu.

Umarnin don amfani (sashi)

An ƙaddara shi akayi daban-daban dangane da buƙatar jikin mutum na insulin. An wajabta ta daga likitan halartar gwargwadon sakamakon binciken. Matsakaicin matsakaici yana daga 0.5 zuwa 1 IU / kg kowace rana.

Ana amfani dashi don gudanar da subcutaneous. Ana iya amfani dashi azaman monotherapy, kuma a hade tare da wasu kwayoyi. Mafi sau da yawa, ana yin allura a cinya, kafada, gindi ko ciki. Wajibi ne don canza wuraren allura don guje wa haɓakar lipodystrophy. Sabili da haka, a cikin wata daya, baza ku iya tsayar da miyagun ƙwayoyi sau biyu a wuri guda ba.

Haihuwa da lactation

Ana iya amfani dashi a lokacin duk lokacin haihuwa da kuma lokacin shayarwa, saboda baya haifar da wata barazana ga ci gaban tayin kuma baya shiga cikin madarar nono.

Uwar tana buƙatar daidaitattun matakan sutura akai-akai, saboda a yayin lokuta daban-daban na ciki, buƙatar insulin na iya canzawa. Don haka, yawanci yakan raguwa a cikin farkon farkon abubuwa kuma yana ƙaruwa daga baya.

Sabili da haka, ya kamata koyaushe kula da yanayinku da hana hypoglycemia wanda ke cutar da yaro musamman.

Sharuɗɗan da yanayin ajiya

Rayuwar shelf - shekaru 2.5, bayan ranar karewa ana zubar dashi.

An adana shi a cikin bushe, wuri mai duhu, a cikin firiji a zazzabi na 2 zuwa 8 ° C. Kar a daskare! Bayan buɗe kunshin, rayuwar shiryayye shine makonni 6 a zazzabi wanda bai wuce digiri 30 ba.

Dole ne a kiyaye shi daga yara.

Kwatanta tare da analogues

Akwai da yawa analogues na wannan magani.

Suna, abu mai aiki	Mai masana'anta	Ribobi da fursunoni	Farashin, rub.
Humulin, insulin matsakaici.	"Eli Lilly", Amurka, "BIOTON S.A.", Poland.	Ribobi: ana iya amfani dashi yayin daukar ciki da cikin yara ‘yan kasa da shekaru 18.

Cons: farashin ya fi girma, amfani tare da taka tsantsan a cikin mutane sama da 65 shekara.

daga 500 (ga kwalban 10 ml), daga 1100 (na katako). "Biosulin", insulin-isophan.Pharmstandard-Ufavita, Rasha.Ribobi: ba yawa sakamako masu illa.

Cons: Ana buƙatar kulawa da likitanci lokacin da ake amfani da shi a cikin tsofaffi marasa lafiya, kuma yana ɗaukar dogon lokaci don jira har sai lokacin da aikin ya fara.

daga 500 (kwalban 10 ml), daga 900 (katako don maganin sirinji). Levemir, insulin detemir.Novo Nordisk, Denmark.Ribobi: Yana ɗaukar tsawon lokaci, ba ya da furotin, wanda zai haifar da rashin lafiyan jijiyoyin jiki

Cons: tsada mai tsada, ba a ba da shawarar ga yara ƙanana 6.

daga 1800 (sirinjin almara).

Sauya magani ɗaya tare da wani mai yiwuwa ne kawai ta likita. An haramta shan magani!

Insulin Protafan: umarnin don maye gurbin da nawa

Maganin cutar sankara na zamani ya ƙunshi yin amfani da nau'ikan insulin guda biyu: don biyan buƙatun asali da rama sukari bayan cin abinci. Daga cikin magungunan matsakaici ko tsaka-tsakin mataki, layin farko a cikin ranking yana mamaye insulin Protafan, kasuwar sa kamar kashi 30%.

Mawallafin, kamfanin Novo Nordisk, ya shahara a duniya a yaki da cutar sankarau. Godiya ga bincikensu, insulin ya bayyana a cikin nesa 1950 tare da aiki mai tsayi, wanda ya sanya ya yiwu a sauƙaƙe rayuwar marasa lafiya. Protafan yana da babban matakin tsarkakewa, tsayayye kuma sakamako mai tsinkaye.

Bruef umarnin

Ana yin Protafan ta yanayin halitta. Ana gabatar da kwayar halitta ta DNA don dacewa da insulin a cikin ƙwayoyin yisti, bayan haka suka fara samar da proinsulin. Insulin da aka samo bayan magani na enzymatic ya zama daidai ga mutum.

Don tsawaita aikin, ana cakuda hormone tare da protamine, kuma ana yin sukuni ta amfani da fasaha na musamman. Magungunan da aka samar ta wannan hanyar ana kasancewa da shi ta hanyar daidaituwa na yau da kullun, kuna iya tabbata cewa canjin kwalban ba zai shafi sukarin jini ba.

Ga marasa lafiya, wannan yana da mahimmanci: ƙarancin abubuwan da ke shafar aikin insulin, mafi kyawun diyya ga masu ciwon sukari za su kasance.

Akwai Protafan HM a cikin gilashin gilashi tare da 10 ml na bayani. A wannan nau'in, magungunan ke karɓar magungunan da masu ciwon sukari waɗanda ke yin allurar insulin tare da sirinji. A cikin kwali kwali 1 kwalban da umarnin don amfani.

Protafan NM Penfill shine kwalin kwandon shara 3 ml wanda za'a iya sanyawa a cikin allon nominin NovoPen (ɓangaren mataki 1) ko NovoPen Echo (matakan 0.5 raka'a). Don dacewa da haɗuwa a cikin kowane katun gilashin ƙwallon gilashi. Kunshin ya ƙunshi katako guda 5 da umarnin.

Rage sukari na jini ta hanyar jigilar shi zuwa kyallen takarda, inganta haɓakar glycogen a cikin tsokoki da hanta. Yana karfafa samuwar sunadarai da mai, saboda haka, yana taimakawa samun nauyi.

Ana amfani dashi don kula da sukari mai azumi na al'ada: a dare da tsakanin abinci. Ba za a iya amfani da Protafan don gyaran glycemia ba, an yi amfani da gajerun abubuwan insulins don waɗannan dalilai.

Bukatar insulin yana ƙaruwa tare da damuwa na tsoka, raunin jiki da na tunani, kumburi, da cututtuka masu yaduwa. Yin amfani da barasa a cikin ciwon sukari ba a son shi, saboda yana haɓaka ƙazantar cutar kuma yana iya tayar da hawan jini.

Ana buƙatar yin gyaran fuska yayin ɗaukar wasu magunguna. Increara - tare da yin amfani da diuretics da wasu magungunan hormonal. Rage - dangane da kulawa ta lokaci guda tare da allunan rage sukari, tetracycline, asfirin, magungunan antihypertensive daga rukunin masu hana masu karɓa na AT1 da masu hana ACE.

Sakamakon mafi kyawun sakamako na kowane insulin shine hypoglycemia. Lokacin amfani da magungunan NPH, haɗarin faduwar sukari da daddare ya fi girma, tunda suna da babban aiki.

Nocturnal hypoglycemia yana da haɗari sosai a cikin ciwon sukari na mellitus, tun da mai haƙuri ba zai iya yin bincike da kawar da su da kansu ba.

Sugararancin sukari da daddare sakamakon sakamako ne da aka zaɓa ba daidai ba ko kuma yanayin aikin mutum.

A cikin ƙasa da 1% na masu ciwon sukari, Protafan insulin yana haifar da halayen rashin lafiyan gida mai sauƙi a cikin nau'i na fitsari, ƙaiƙayi, kumburi a wurin allura. Yiwuwar rashin lafiyar ƙwayar cuta mai haɗari ya ƙasa da 0.01%. Canje-canje a cikin kitse na subcutaneous, lipodystrophy, na iya faruwa. Hadarinsu yana da girma idan ba a bi hanyoyin allurar ba.

An hana Protafan yin amfani da shi a cikin marasa lafiya da ke da ƙaiƙayi ko ƙaiƙayin Quincke na wannan insulin. A matsayin madadin, yana da kyau a yi amfani da ba insulins na NPH tare da abun kama, amma insulin analogues - Lantus ko Levemir.

Bai kamata masu amfani da cutar ta masu amfani da cutar Protafan suyi amfani da su su hana shi yawan zubar jini ba, ko kuma idan an goge alamun sa. An gano cewa analogues na insulin a wannan yanayin suna da aminci sosai.

Bayanin	Protafan, kamar duk abubuwan NPH, suna ɓoye fuloji. Asan ƙasa akwai farin hazo, a sama - ruwa mai translucent. Bayan an gauraya, maganin gaba ɗaya zai zama fari ɗaya. Maida hankali ne akan abu mai aiki shine raka'a 100 a kowace milliliter.
Sakin Fom
Abun ciki	Abunda ke aiki shine insulin-isophan, mai taimako: ruwa, sinadarin protamine don tsawanta tsawon lokacin aiki, phenol, metacresol da zinc ion azaman abubuwan kiyayewa, abubuwa don daidaita acidity na mafita.
Aiki
Alamu	Ciwon sukari a cikin marasa lafiya na buƙatar insulin far, ba tare da la'akari da shekaru ba. Tare da nau'in cuta ta 1 - daga farawar rikicewar carbohydrate, tare da nau'in 2 - lokacin da magungunan rage sukari da rage cin abinci ba su isa sosai, kuma haemoglobin glycated ya wuce 9%. Cutar sankarar mahaifa a cikin mata masu juna biyu.
Zaɓin sashi	Umarnin ba ya ƙunshi yawan shawarar da aka ba da shawarar, tun da adadin insulin da ake buƙata ga masu ciwon sukari daban ya sha bamban. An lasafta shi bisa dalilin azumtar data glycemia. An zaɓi adadin insulin don safe da maraice na yamma - lissafin kashi na yawan insulin ga duka nau'ikan.
Gyara daidaitawa
Side effects
Contraindications
Adanawa	Ana buƙatar kariya daga haske, yanayin sanyi da kuma yawan zafi (> 30 ° C). Dole ne a adana vials a cikin akwati, ya kamata a kiyaye insulin a cikin sirinji na alƙalmi tare da hula. A cikin yanayin zafi, ana amfani da na'urorin sanyaya musamman don jigilar Protafan. Yanayin ingantaccen yanayi na tsawon lokaci (har zuwa makonni 30) ajiyar kayayyaki ko kofar firiji. A dakin zafin jiki, Protafan a cikin farawar vial yana tsawon makonni 6.

Lokacin aiki

Adadin shigowar Protafan daga kashin karkashin kasa zuwa cikin jini a cikin marassa lafiya da ke dauke da cutar siga ya sha bamban, don haka ba shi yiwuwa a tsinkaya daidai lokacin da insulin ya fara aiki. Darajar bayanai:

Daga allura zuwa bayyanar hormone a cikin jini, kimanin awa 1.5 suka wuce.
Protafan yana da babban aiki, a cikin yawancin masu ciwon sukari yana faruwa ne awanni 4 daga lokacin gudanarwa.
Matsakaicin tsawon lokacin aiki ya kai awanni 24. A wannan yanayin, dogaro da tsawon lokacin aiki akan kashi an samo shi. Tare da gabatar da raka'a 10 na Protafan insulin, za a lura da rage girman sukari na kimanin awanni 14, raka'a 20 na kimanin awanni 18.

Bayanin allura

A cikin mafi yawan lokuta tare da ciwon sukari, gudanarwa na Protafan na lokaci biyu ya isa: da safe da kuma kafin lokacin kwanciya. Yakamata allurar maraice ya isa ya kula da glycemia ko'ina cikin dare.

Sannu Sunana Alla Viktorovna kuma ba ni da ciwon sukari! Yayi min kwanaki 30 kawai da 147 rubles.don dawo da sukari zuwa al'ada kuma kada ku dogara da kwayoyi marasa amfani tare da tarin sakamako masu illa.

>>Za a iya karanta labaru na dalla-dalla a nan.

Sharuɗɗa don madaidaicin kashi:

sukari da safe daidai yake da lokacin kwanciya
babu yawan rashin bacci da daddare.

Mafi yawan lokuta, yawan sukari na jini yakan tashi ne bayan karfe 3 na safe, lokacin da samar da kwayoyin halittun dake cikin jiki suke aiki sosai, kuma tasirin insulin ya raunana.

Idan gangar jikin Protafan ta ƙare da wuri, haɗarin kiwon lafiya mai yiwuwa ne: rashin lafiyar da ba a sani ba da daddare da kuma sukari mai yawa da safe. Don kauce masa, kuna buƙatar bincika matakin sukari na lokaci-lokaci a 12 da 3 hours.

Ana iya canza lokacin allurar maraice, yana dacewa da halayen miyagun ƙwayoyi.

Siffofin aikin kananan allurai

Tare da nau'in ciwon sukari na 2, ciwon sukari a cikin mata masu juna biyu, a cikin yara, a cikin manya akan rage cin abinci mai ƙoshin abinci, buƙatar NPH insulin na iya zama ƙananan. Tare da ƙaramin ƙwayar guda ɗaya (har zuwa raka'a 7), tsawon lokacin aikin Protafan ana iya iyakance shi zuwa 8 hours. Wannan yana nufin cewa allurar guda biyu da aka bayar ta hanyar umarnin ba zai isa ba, kuma a tsakanin sukarin jini zai karu.

Ana iya magance wannan ta hanyar allurar Protafan insulin sau 3 a cikin kowane awa 8: ana ba da allurar farko nan da nan bayan farkawa, na biyu yayin cin abincin rana tare da gajeren insulin, na uku, mafi girma, kafin lokacin bacci.

Nazarin masu ciwon sukari, ba kowa bane yake cin nasarar samun kyakkyawan sakamako ga masu cutar siga ta wannan hanyar. Wani lokacin kashi na dare yakan daina aiki kafin farkawa, kuma sukari da safe yana da yawa. Theara yawan kashi yana haifar da wucewar insulin da hauhawar jini. Hanya daya tilo daga wannan yanayin ita ce canzawa zuwa insulin analogues tare da tsawon lokacin aiki.

Addu'ar abinci

Masu ciwon sukari a kan ilimin insulin yawanci ana rubutasu duka a matsakaici da kuma gajere insulin.Ana buƙatar gajere don rage glucose wanda ke shiga cikin jini daga abinci. Hakanan ana amfani dashi don gyara glycemia. Tare tare da Protafan yana da kyau a yi amfani da ɗan gajeren shiri na masana'antun guda ɗaya - Actrapid, wanda kuma ana samunsa a cikin vials da katako don alkairin ƙwayar sirinji.

Lokacin gudanar da insulin Protafan ba ya dogara da abinci ta kowace hanya, kusan daidai lokacin da ke tsakanin injections ya isa. Da zarar kun zabi lokacin da ya dace, kuna buƙatar bin ta koyaushe.

Idan ya dace da abinci, za'a iya yin amfani da Protafan tare da ɗan insulin.

A lokaci guda hada su a cikin sirinji iri ɗaya ba a so, tun da alama yana iya yin kuskure tare da kashi kuma rage girman aikin gajeren hormone.

Matsakaicin adadin

A cikin ciwon sukari mellitus, kuna buƙatar allurar insulin kamar yadda ake buƙata don daidaita daidaituwar glucose. Umarnin don amfani bai kafa iyakar awo ba. Idan madaidaicin adadin insulin na Protafan ya haɓaka, wannan na iya nuna juriya na insulin. Tare da wannan matsalar, ya kamata ka nemi likitanka. Idan ya cancanta, zai rubuta magungunan da ke inganta aikin hodar.

Amfani da juna biyu

Idan tare da ciwon sukari na gestational ba zai yiwu a cimma daidaitaccen ƙwayar cuta ba kawai ta hanyar abinci, an tsara masu maganin insulin. An zaɓi maganin da maganin ta musamman a hankali, tunda duka hypo- da hyperglycemia suna kara haɗarin lalata cikin yaro. An yarda da insulin Protafan don amfani yayin daukar ciki, amma a mafi yawan lokuta, analogues na dogon lokaci zai zama mafi tasiri.

Shin kana shan azaba da cutar hawan jini? Shin kun san hauhawar jini yana haifar da bugun zuciya da bugun jini? Normalize your matsa lamba da ... Ra'ayoyi da kuma bayani game da hanyar karantawa anan >>

Idan ciki ya faru da nau'in ciwon sukari na 1, kuma macen ta sami nasarar rama cutar ta Protafan, ba a buƙatar canza magani.

Rashin nono yana tafiya daidai da ilimin insulin. Protafan ba zai haifar da wata illa ga lafiyar jaririn ba. Insulin ya shiga cikin madara a cikin adadi kaɗan, bayan wannan sai ya karye cikin narkewar ƙwayar yaron, kamar kowane furotin.

Protafan analogues, juyawa zuwa wani insulin

Cikakkun analogues na Protafan NM tare da abubuwa guda masu aiki da kuma lokacin aiki kusa sune:

Humulin NPH, Amurka - babban ɗan takara, yana da kasada kasuwa fiye da 27%,
Insuman Bazal, Ranska,
Biosulin N, RF,
Rinsulin NPH, RF.

Daga ra'ayi game da magani, canji na Protafan zuwa wani magani na NPH ba shine canzawa zuwa wani insulin ba, kuma har ma a cikin girke-girke kawai ana nuna abu mai aiki, kuma ba takamaiman alama ba.

A aikace, irin wannan canjin ba zai iya dakatar da sarrafa glycemic kawai ba na ɗan lokaci kuma yana buƙatar daidaita sashi, amma kuma yana haifar da rashin lafiyar.

Idan cutar haemoglobin ta al'ada al'ada ce kuma hypoglycemia yana da wuya, ba bu mai kyau a ƙi insulin Protafan ba.

Bambancin insulin analogues

Analogs insulin na insulin kamar Lantus da Tujeo basu da kololuwa, ana iya jure su kuma ba sa haifar da rashin lafiyan jiki. Idan mai ciwon sukari yana da cututtukan cututtukan ƙwayar cuta na jiki ko ƙoshin sukari ba tare da wani dalili na musamman ba, ya kamata a maye gurbin Protafan tare da insulins na yau da kullun.

Babban hasara shine babban farashin su. Farashin Protafan kusan 400 rubles. na kwalba da 950 domin tattara kayan katako na almakashi. Insulin analogues kusan sau 3 sun fi tsada.

Tabbatar koya! Kuna tsammanin kwayoyin hana daukar ciki da insulin sune kawai hanyar da za a kula da sukari a ƙarƙashin? Ba gaskiya bane! Kuna iya tabbatar da wannan da kanku ta hanyar amfani da ... karanta ƙarin >>