Umarnin don amfani da Glidiab MV

Hanyar warkewar cutar sankara ba kawai canjin abinci ba ne, har ma da amfani da magunguna na musamman.

Tare da nau'in cuta ta 2, mutane suna sau da yawa ana ba da magunguna don cin nasara glycemia na al'ada. Suchaya daga cikin irin wannan maganin shine Glidiab MV.

Bayani na gaba daya, abun da ya shafi da kuma sakin

Magungunan Glidiab MV yana ɗaya daga cikin abubuwan da aka samo asali na sulfonylurea (ƙarni 2), saboda haka an yi niyya don haɓaka sel beta wanda ke cikin pancreas.

Kamfanin samar da magunguna ana yin shi ne a yankin Moscow ta Kamfanin Kamfanin Magrik da Akrikhin kuma ana ɗaukar shi analog na hypoglycemic Allunan Diabeton MV, wanda aka ƙera a Faransa. Wakilin yana da sashi nau'in yanayin da aka sake shi ta hanyar sakewa da aka sake shi.

Ana samun maganin a cikin nau'ikan allunan da ke da farin witish. Suna kama da bayyanar fayel silinda. Akwai magungunan a cikin fakitoci 30 ko allunan 60.

Idan aka kwatanta da Diabeton MV, wanda ke da sashi na 0.06 g, Glidiab MV ya ƙunshi rabin bangaren aiki (0.03 g).

• Gliclazide shine babban abu,
• cellulose (microcrystalline),
• hydroxypropyl methylcellulose,
• magnesium stearate,
• Aerosil

An tsara yawancin marasa lafiya Glidiab 80, wanda ya ƙunshi kashi mai aiki, ba 30 MG ba, amma 80 MG a cikin kowane kwamfutar hannu.

Aikin magunguna

Abubuwan haɗin Glidiab MV suna shafar jikin mutum kamar haka:

• hanzarta ɓoye insulin da aka samar a cikin ƙwayar cuta,
• kara jijiya nama zuwa ga hormone samar,
• rage tazara daga lokacin cin abinci zuwa sakin insulin,
• a ƙarƙashin rinjayar wannan ƙwayar, an sake dawo da ɓoye insulin a farkon lokaci idan aka kwatanta da sauran magungunan sulfonylurea,
• haɓaka aikin microcirculation saboda tarin ƙwayoyin platelet, maidowa da yanayin jijiyoyin jijiyoyin jiki da ƙananan haɗarin microthrombosis,
• rage yawan cutar glycemia,
• taimaka kawar da protenuria,
• rage jinkirin ci gaban retinopathy,
• ba da gudummawa ga asarar nauyi, batun cin abincin wajibi.

Pharmacokinetics

Tsarin sha, rarrabuwar shi a cikin jiki, metabolism da excretion na abubuwan da ake dasu suna faruwa kamar haka:

1. Damuwa. Kusan maganin yana kusan samunshi ta hanyar narkewar hanji (gastrointestinal fili). Mayar da hankali yana ƙaruwa a cikin plasma a hankali, har ya kai matsakaicinsa daga lokacin gudanarwa bayan sa'o'i 6 ko 12. Abun ciye-ciye ba ya shafar yawan sha. Magungunan yana aiki tsawon sa'o'i 24.
2. Rarraba. Sadarwa tare da ƙwayoyin plasma da abubuwan haɗin magunguna an saita su a 95%.
3. Tsarin rayuwa. Wannan tsari yana faruwa a cikin hanta, ana nuna shi ta hanyar samar da daidaitattun metabolites marasa aiki.
4. Kiwo. Murmushi yana faruwa ta hanyar kodan a cikin hanyar metabolites, kawai 1% na maganin yana fitowa tare da fitsari. Cire rabin rayuwar maganin yana faruwa ne a cikin awanni 16.

Tsarin hanyoyin samar da magani na maganin a cikin tsofaffi marasa lafiya ba su canzawa.

Manuniya da contraindications

Allunan Glidiab MV sune magungunan hypoglycemic, sabili da haka, ana amfani dasu a cikin maganin cututtukan type 2, lokacin da sauran hanyoyin rage glucose bai dawo da mai nuna alamar al'ada ba.

Contraindications zuwa shan miyagun ƙwayoyi sune:

• ketoacidosis
• koda mai aiki,
• Type 1 ciwon sukari
• coma (ciwon sukari ko hyperosmolar),
• aiki
• raunin da ya faru
• hanji na baka,
• ciki
• yanayin haddasa cutarwar jiki (alal misali, cututtukan yanayi na kamuwa da cuta),
• leukopenia
• ƙonewa mai yawa
• rashin hankali ga abubuwa a cikin abun da ke ciki na samfurin,
• nono.

Umarnin don amfani da umarni na musamman

Sashi na magani ya dogara da halaye na hanyar ciwon sukari da kuma bayyanannunsa, saboda haka likita ya zaɓi shi daban-daban ga kowane haƙuri.

A farkon shan magani, ana bada shawarar sashi na 30 MG ko kwamfutar hannu 1. Ya danganta da yanayin mai haƙuri yayin maganin, ana iya ƙara adadin abu mai aiki a kowace rana zuwa 120 MG (matsakaicin adadin).

Allunan ana daukar su a baki yayin karin kumallo (sau daya a rana). Rashin rauni na koda (tare da creatinine daga 15 zuwa 80 ml / min) baya buƙatar daidaita sashi.

A farkon farawar magani kuma har sai an zaɓi kashin da ake buƙata, marasa lafiya koyaushe suna fuskantar matsalar rashin ƙarfi da ƙwaƙwalwar jiki bai kamata su yi aikin da ke buƙatar saurin amsawa ko ƙara yawan kulawa ba.

Kada mata suyi amfani da maganin a lokacin haihuwar yaro, harma da shayarwa.

Babban rauni na lalacewar kodan ko hanta ya haramta amfani da miyagun ƙwayoyi har ma da ƙarancin magunguna.

1. Abubuwan da ake buƙata don cimma tasirin aikace-aikacen shine bi abinci da motsa jiki matsakaici. A cikin abincin yau da kullun, carbohydrates ya kamata ya kasance a cikin ƙaramin adadin.
2. Yana da mahimmanci cewa ana kula da glycemia kafin da bayan abinci don a iya daidaita sashi gwargwadon sakamakon aunawa.
3. Don tiyata ko cutar sikari da ta lalata, yakamata a maye gurbin maganin da allurar insulin.
4. Don guje wa faruwar cututtukan jini, da fitsarin disulfiram, kar ku sha barasa.
5. Haramun ne tsallake abinci, watsi da abubuwan ciye-ciye a lokacin yunwar.
6. Kafin aiki mai wahala, ya kamata a rage kashi.

Mafi hankali ga magungunan cututtukan jini sune:

• mutane a cikin tsufa
• marasa lafiya waɗanda ba za su iya samun daidaitaccen abinci ba,
• mutane masu rauni a jiki
• marasa lafiya da ke kama da cuta kamar ƙarancin ƙwaƙwalwar ƙwayar cuta na ciki-rashin ƙarfi.

Side effects da yawan abin sama da ya kamata

Shan kwayoyin magani na iya haifar da halayen masu zuwa a cikin mutum:

• dangane da tsarin endocrine - hypoglycemia tare da halayyar jijiyoyin kai, zazzagewa, rauni, kasala, tashin hankali, rashi, hangen nesa da hangen nesa da daidaituwa da motsi,
• daga narkewa daga ciki - dyspepsia, anorexia, hargitsi a hanta,
• leukopenia, thrombocytopenia, anemia,
• Bayyanar rashin lafiyan (itching, fitsari, ko urticaria).

Tare da yawan ƙwayar ƙwayar ƙwayar cuta, hypoglycemia na faruwa. Don kawar da alamun ta, ya isa ya cinye carbohydrates da yawa, muddin mutumin yana sane. A cikin yanayin da mai haƙuri ba zai iya ɗaukar abinci da kansa ba, ya kamata a ba shi maganin glucose na ciki (40%) da allura ta ciki na glucagon. Bayan dawo da hankali ga mutumin da yake da ciwon sukari, har yanzu kuna buƙatar samun cizo don guje wa sake yawan glucose a jiki.

Yin hulɗa tare da wasu magunguna da analogues

Yin amfani da wasu magunguna a cikin haɗin gwiwa tare da Glidiab MV na iya haɓaka ko rage tasirin hypoglycemic.

Hada magunguna tare da kwayoyi kamar:

• ACE hanawar,
• jami'in antifungal (fluconazole),
• NSAIDs
• maganin antihistamines
• Fibrates
• maganin cututtukan tarin fuka
• Salicylates,
• Pentoxifylline
• Ethanol
• kwayoyi masu hana tubular ɓoye ɓoye

Ana magance tasirin hypoglycemic idan aka haɗu da magunguna masu zuwa:

• barbiturates
• karin bayani
• Furosemide
• kwayoyin halittar don kula da aikin ta thyroid,
• shirye-shiryen lithium
• estrogens
• wajen maganin hana haihuwa.

Daga cikin magungunan da ke da tasiri iri ɗaya kamar allunan Glidiab MV, ana lasafta abubuwa masu zuwa:

• Meglimide
• Alfika
• Glibetic,
• Clay,
• Glimepiride
• Eglim
• Girma
• Glibenclamide,
• Glenrenorm.

Abubuwan bidiyo game da ciwon sukari, magani da rigakafinsa:

Ra'ayoyin marasa lafiya da likitoci

Daga sake dubawa na masu haƙuri, zamu iya yanke hukuncin cewa an yarda da miyagun ƙwayoyi da tasiri. Koyaya, likitoci sun dage kan amfani da maganin ne kawai bayan sun tattauna da kwararrun likitocin.

Da kyau magani. A kan tushen yanayin matsananciyar wahala, na sami kusan kilogram 30, duk da cewa ban canza abincina ba. A sakamakon haka, na sami farin jini mai yawa. Likita ya umurce ni da in ɗauki Allunan 2 na Glidiab MV kowace safiya, kuma in sha kwamfutar hannu 1 na Glucofage 1000 da maraice .. Godiya ga wannan tsarin kulawa, ƙididdigar glucose ta faɗi da raka'a 4 kuma yana ci gaba da kasancewa a kusan 7 mmol / L kullum.

Kristina, mai haƙuri, shekara 47

Magungunan yana da sauƙin amfani. Glidiab CF yana da contraindications da yawa, don haka mara lafiya ya kamata su fara ɗaukar shi da kansu ba tare da yardar farko daga likitan halartar ba. Wajibi ne a kula da cutar glycemia a kai a kai tare da bincika tasirin maganin cututtukan ƙwayar cuta tare da mahaɗan endocrinologist. Tare da tsarin zaɓaɓɓen magani da aka zaɓa daidai, yana yiwuwa a hanzarta daidaita alamomin glucose. An ba da magunguna a cikin kantin magani tare da takardar sayen magani, amma citizensan ƙasa da ke fama da wannan cuta suna karɓar kyauta kyauta, ƙarƙashin kulawar da kwararru na asibitin su ke yi akai.

Victor Vladimirovich, likita

Farashin allunan 60 na Glidiab MV a cikin kunshin kusan 200 rubles.