Acetylsalicylic acid, foda: umarnin don amfani

Kowace jaka ta ƙunshi:

Acetylsalicylic acid - 500 MG,

phenylephrine hydrotartra t - 15.58 MG,

Chlorphenamine maleate - 2.00 MG,

magabata: citric acid citrus 1220 mg, sodium bicarbonate 1709.6 mg, lemon tsami 100 m g, quinoline mai launin shuɗi (E 104) 0.32 mg.

Pharmacodynamics na miyagun ƙwayoyi

Hadin magunguna, sakamakon abin da ya faru ne sakamakon abubuwan da ke tattare da su:

Acetylsalicylic acid(TAMBAYA) Yana da farfadowa, antipyretic, tasirin anti-mai kumburi, wanda ya faru ne saboda hana enzymes cyclooxygenase da ke cikin aikin prostaglandins. Acetylsalicylic acid yana hana haɗuwar platelet, yana toshe haɗarin thromboxane A2.

Phenylephrine Abun tausayi ne kuma, yana da tasirin vasoconstrictor, yana rage kumburi da hancin mucous na sinus na hanci, wanda ke sauƙaƙa numfashi.

Chlorphenamine yana cikin rukunin magungunan antihistamines, yana sauƙaƙe bayyanar cututtuka irin su lalata da ƙoda.

Contraindications Aspirin Complex a foda fom

- Hypersensitivity na acetylsalicylic acid da sauran NSAIDs ko wasu abubuwan maganin,

- erosive da ulcerative raunuka na gastrointestinal fili (a cikin m lokaci), na kullum ko na juyawa hanya na peptic miki,

- fuka-fuka da ke haifar da daukar salicylates ko wasu NSAIDs,

- rikicewar zubar jini, irin su haemophilia, hypoprothrombinemia,

- Cutar cutar hanta da / ko koda,

- polyposis hanci da ke hade da asma da rashin haƙuri zuwa acid na acetylsalicylic,

- haɓaka ƙwayar thyroid,

- haɗe tare da amfani da maganin anticoagulants na baki,

- haɗe tare da mai amfani da abubuwan hana kwayoyin oxidase, ciki har da kwanaki 15 bayan dakatar da amfani da su,

- Haɗin maganin methotrexate a cikin kashi 15 na MG a mako ɗaya ko sama da haka,

- ciki (I da III trimester), lokacin shayarwa.

Ba a ba da magunguna ga yara 'yan ƙasa da shekara 15 tare da m cututtuka na numfashi lalacewa ta hanyar kamuwa da hoto, saboda hadarin Reye syndrome (encephalopathy da m hanta tare da m ci gaban hanta).

Sashi da gudanar da aikin Asfirin Complex a cikin foda

Narke abubuwan da ke cikin jaka a gilashin ruwa zazzabi daki. Kai a baki bayan cin abinci.

Manya da yara sama da shekaru 15: cokali daya a kowace awa 6-8.

Matsakaicin adadin yau da kullun shine sachets 4, tazara tsakanin allurai na miyagun ƙwayoyi ya zama aƙalla 6 hours.

Tsawon lokacin jiyya (ba tare da tuntuɓar likita ba) bai wuce kwanaki 5 ba lokacin da aka wajabta shi azaman maganin rage shan wahala da kuma fiye da kwanaki 3 a matsayin maganin hana haifuwa.

Sakamakon sakamako na magani

Jikin duka: hyperhidrosis.

Gastrointestinal fili: tashin zuciya, dyspepsia, vomiting, ciki da duodenal ulcers, jini na ciki, ciki har da ɓoye (black stool).

Allergic halayen: urticaria, eczematous, fatar fata, angioedema (edema na Quincke), hanci mai hanji, hanji da kuma gajeruwar numfashi,

Tsarin ciwan kai: hypoprothrombinemia.

Tsarin juyayi na tsakiya da gabobin gabbai: farin ciki, tinnitus, ciwon kai, raunin ji.

Tsarin Urinary: gazawar koda, m intermerulonephritis.

Aikin magunguna

Acetylsalicylic acid shine magungunan anti-mai kumburi wanda ba shi da steroidal wanda ke da tasirin antipyretic, analgesic, anti-inflammatory, yana hade da hana ayyukan COX1 da COX2 wadanda ke tsara tsarin ayyukan prostaglandins. Taimakawa aikin kirar thromboxane A₂ a cikin platelet, rage haɗuwa, platelet mannewa da thrombosis, suna da tasirin anti-tarawar. Bayan gudanar da aikin parenteral na maganin mai ruwa-ruwa, sakamako na analgesic yafi magana sosai fiye da lokacin sarrafa baki na acetylsalicylic acid. Tare da subconjunctival da parabulbar gudanarwa, yana da ƙayyadadden sakamako na anti-kumburi da anti-tarawa, wanda pathogenetically ya tabbatar da amfani da miyagun ƙwayoyi don magance cututtukan kumburi a cikin asalin asalin da asalin. An bayyana tasirin anti-mai kumburi sosai lokacin amfani da miyagun ƙwayoyi a cikin lokacin lokacin aikin kumburi a cikin ido. Tare da raunukan raunuka na ido ɗaya, ƙwayar ta kawar da juyayi na tausayi (abokantaka) na abokan haɗin kai.

Sauran shirye-shiryen Acetylsalicylic acid

Fom ɗin saki

Foda don maganin shafawa. Kyakkyawan foda mai tsabta daga kusan fari zuwa fari tare da tintaccen launin shuɗi.

Kowace jaka ta ƙunshi:

abubuwa masu aiki - Acetylsalicylic acid (500 MG), bitylerate phenylephrine (15.58 MG), chlorpheniramine maleate (2.00 mg),

excipients - anhydrous citric acid, sodium bicarbonate, dandano lemun tsami, rigar quinoline.

3547.5 MG na miyagun ƙwayoyi a cikin jakar takarda, an ƙare tare da tsare tsare na aluminium da fim ɗin polyethylene, an haɗa fakiti 2 a cikin tsiri 1 (an raba shi ta hanyar tsalle-tsalle), tsararraki 5 tare da umarnin don amfani a akwatin kwali.

Alamu don amfani

Processes Hanyoyin kumburi a cikin asalin asali da asalin mahalli: (conjunctivitis, blepharitis, blepharoconjunctivitis, meibomyitis, halal, keratitis, scleritis, keratouveitis),

· Kwayar cutar rashin daidaituwa na kowane yanayin ilimin otiology, uveitis na ciki (post-traumatic, postoperative, contusion, burn, chorioretinitis, neuritis, gami da retrobulbar neuritis, optochiasal arachnoiditis),

· Rigakafin yaduwar cututtukan zuciya,

Pre Yin rigakafin rikodin jijiyoyin ciki da rikice rikice na jini na yanayi mai ban sha'awa (musamman, myosis na ciki da na macular edema bayan tiyata na cirewa tare da shigar da ruwan tabarau, maganin farfadowa a cikin microsurgery na laser, yanayin thromboembolic a ophthalmology).

Side sakamako

Acetylsalicylic acid

• Jiki gabaɗaya: hyperhidrosis.
• Gastrointestinal fili: tashin zuciya, dyspepsia, vomiting, na ciki da 12 duodenal ulcers, jini na ciki, ciki har da ɓoye (baƙar fata).
• Allergic halayen: urticaria, exanthematous fata fitsari, angioedema (ta edema Quincke), hanci mai gudu, bronchospasm da kuma m numfashi.
• Tsarin hematopoietic: hypoprothrombinemia.
• Tsarin juyayi na tsakiya da gabobin azanci: farji, tinnitus, ciwon kai, raunin ji.
• Tsarin Urinary: gazawar koda, maƙarƙashiyar cutar mahaifa.
• A lokuta da dama (

Sakawa lokacin

Manya da yara kanana shekaru 15 sanya 1 sachet a kowane sa'oin 6-8. Matsakaicin adadin yau da kullun shine sachets 4, tsakani tsakanin allurai na miyagun ƙwayoyi ya zama awanni 6.

Tsawon lokacin jiyya (ba tare da tuntuɓar likita ba) bai kamata ya wuce kwanaki 5 ba yayin amfani da shi azaman maganin maye da fiye da kwana 3 azaman maganin hana haifuwa.

Ya kamata a sha magani a baki bayan cin abinci, bayan ya warwatsa abubuwan da ke cikin kwalin a gilashin ruwa a zazzabi a daki.

Hulɗa da ƙwayoyi

Acetylsalicylic acid

Tare da amfani da ethanol lokaci guda, cimetidine da ranitidine tare da acetylsalicylic acid, ana inganta tasirin mai guba na ƙarshen.

Tare da yin amfani da magungunan heparin da magungunan kashe kansa kai tsaye tare da acetylsalicylic acid, haɗarin zub da jini yana ƙaruwa saboda taɓarɓare aikin platelet da kuma kawar da magungunan anticoagulants na kai tsaye daga sadarwa tare da kariyar plasma jini.

Acetylsalicylic acid yana rage yawan shan indomethacin, phenoprofen, naproxen, flurbiprofen, ibuprofen, diclofenac, piroxicam.

Tare da yin amfani da GCS a lokaci guda tare da acetylsalicylic acid, haɗarin lalacewar sakandare ga mucosa na ciki yana ƙaruwa.

Acetylsalicylic acid tare da yin amfani da shi a lokaci guda zai iya ƙara yawan ƙwayar phenytoin saboda ƙaura daga aikin haɗin ginin.

Tare da yin amfani da magungunan antidiabetic (tare da insulin) a lokaci guda tare da acetylsalicylic acid, an inganta tasirin hypoglycemic saboda gaskiyar cewa acetylsalicylic acid a cikin babban kashi yana da kaddarorin hypoglycemic kuma yana kawar da abubuwan ƙira na sulfonylurea saboda kariyar plasma jini.

Acetylsalicylic acid tare da yin amfani da lokaci ɗaya zai iya inganta tasirin ototoxic na vancomycin.

Ta hanyar amfani da methotrexate tare da acetylsalicylic acid, ana inganta tasirin methotrexate ta hanyar rage keɓance dangin tare da kawar dashi daga sadarwa tare da sunadarai.

Salicylates tare da yin amfani da lokaci daya yana rage tasirin uricosuric na probenecid da sulfinpyrazone saboda gushewar tubular gasa ta uric acid.

Tare da yin amfani da zidovudine tare da acetylsalicylic acid, an lura da karuwar juna game da tasirin mai guba.

Phenylephrine

Tare da amfani da lokaci guda na phenylephrine da masu hana MAO (antidepressants - tranylcypromine, moclobemide, magungunan antiparkinsonian - selegiline), mummunan sakamako masu illa a cikin nau'i na matsanancin ciwon kai, kara karfin jini da zafin jiki.

Ta hanyar amfani da phenylephrine na lokaci guda tare da beta-blockers, haɓaka hawan jini da bradycardia mai wuya.

Tare da yin amfani da phenylephrine na lokaci guda tare da juyayin juyayi, sakamakon ƙarshen ƙarshen akan tsarin juyayi na tsakiya da tsarin jijiyoyin jini. Jin daɗi, haushi, rashin bacci mai yiwuwa ne.

Yin amfani da phenylephrine kafin cutar shan inhalation yana kara hadarin tashin zuciya. Ya kamata a dakatar da Phenylephrine kwanaki kadan kafin a yi maganin tiyata.

Tare da amfani da alkaloids na Rauwolfia na lokaci guda na iya rage tasirin warkewar cutar phenylephrine.

Tare da yin amfani da phenylephrine tare da maganin kafeyin, na iya inganta yanayin warkewa da sakamako mai guba.

A cikin abubuwan da suka zama ruwan dare, tare da yin amfani da phenylephrine na lokaci guda tare da indomethacin ko bromocriptine, hauhawar jijiya mai ƙarfi na iya haɓaka.

Tare da yin amfani da phenylephrine a lokaci guda tare da maganin antidepressants na rukuni na zaɓin inhibitors na serotonin reuptake inhibitors (fluvoxamine, paroxetine, sertraline), duka hankalin mutum ga jijiyoyin tausayi da haɗarin kamuwa da cututtukan serotonergic na iya ƙaruwa.

Tare da yin amfani da phenylephrine lokaci guda yana rage tasirin sakamako na magungunan antihypertensive daga ƙungiyar masu juyayi (reserpine, guanethidine).

Chlorphenamine

Tare da yin amfani da chlorphenamine na lokaci guda na iya haɓaka tasirin hana ƙwaƙwalwa a cikin tsarin jijiya na ethanol, hypnotics, shakatawa, antipsychotics (antipsychotics), analgesics na tsakiya.

Tare da amfani da lokaci guda na chlorphenamine yana haɓaka tasirin anticholinergic na anticholinergics (atropine, antispasmodics, tricyclic antidepressants, MAO inhibitors).

Form sashi

Granules don maganin baka, 500 MG

Daya daga cikin sachet ya ƙunshi

abu mai aiki - acetylsalicylic acid - 500 MG,

tsofaffi: mannitol, sodium bicarbonate, sodium hydrocytrate, ascorbic acid, dandano Cola, dandano mai tsami, lemo mai ruwan anhydrous, aspartame.

Rawaya mai launin shuɗi daga fari zuwa ɗan rawaya a launi.

Kayan magunguna

Lokacin gudanar da shi, ana amfani da Acetylsalicylic acid cikin hanzari daga hanji. Yana da metabolized a cikin hanta ta hanyar hydrolysis tare da samuwar salicylic acid, tare da conjugation tare da glycine ko glucuronide. Kusan 80% na salicylic acid yana ɗaure ga furotin plasma kuma ana yin saurin rarraba cikin yawancin kyallen da ruwan jiki. Har ilayau ta hanyar shinge kwakwalwa-jini.

Ana amfani da ruwan salicylic acid a cikin madara kuma ya haye mahaifa.

Rabin rayuwar acetylsalicylic acid shine kamar mintina 15, salicylic acid kusan awanni 3 ne. Kwakwalwar Salicylic da metabolites sune ke rabuwa da kodan.

Acetylsalicylic acid (ASA) yana cikin rukunin magungunan anti-inflammatory anti-inflammatory (NSAIDs) kuma yana da lafuzza, antipyretic da tasirin anti-mai kumburi, sannan kuma yana hana hadewar platelet. Hanyar aiwatarwa yana da alaƙa da hana ayyukan cyclooxygenase (COX), babban enzyme a cikin metabolism na arachidonic acid, wanda shine farkon aikin prostaglandins, wanda ke taka rawa sosai a cikin pathogenesis na kumburi, zafi da zazzabi.

Sakamakon analgesic na acetylsalicylic acid yana faruwa ne ta hanyar dabaru guda biyu: yanki (a kaikaice, ta hanyar murƙushewar kwayar prostaglandin) da na tsakiya (saboda hanawar aikin prostaglandin a cikin tsakiya da kuma na jijiyar jijiya).

Sakamakon raguwa a cikin samar da prostaglandins, tasirin su akan cibiyoyin thermoregulation yana raguwa.

Acetylsalicylic acid yana hana haɗuwar platelet ta hanyar toshewar haɗin thromboxane A2 a cikin platelet kuma yana da tasirin antiplatelet.

Side effects

- fatar fata, urticaria, itching, rhinitis, hanci hanci, ambaliyar ruwa, tashin zuciya, bronchospasm, Quincke edema

- zawo, tashin zuciya, amai, jin zafi a cikin yankin na jijiyoyin jiki, asarar ci, da wuya mai saurin kamuwa da cuta (tare da amfani da tsawa da tsawa),

- lokuta masu saurin kamuwa da cutar hanji (na iya faruwa ne sakamakon matsanancin rashin bacci ko rashin ƙarfi na rashin jini / misali rashin ƙarfi na ƙwayar hanji)

- cututtukan basur (bashin hanci, zubar jinni), haɓaka lokacin coagulation jini, thrombocytopenia, anemia

- Reye / Reye syndrome (encephalopathy mai saurin ci gaba: tashin zuciya da rashin jin daɗin bugun ciki, gazawar numfashi, amai, amai, hanta mai ƙarfi, hyperammonemia, hauhawar matakan AST, ALT)

- m gazawar na koda, nephrotic syndrome

- da wuya sosai, cin zarafin wucin gadi na wucin gadi tare da karuwar transaminases yana yiwuwa

- za'a iya samun lokuta na hemolysis da cutar haemolytic a cikin marasa lafiya da raunin glucose-6-phosphat dehydrogenase mai ƙarfi.

Mu'amala da Lafiya

Acetylsalicylic acid yana rage kyautar kyautar ta methotrexate kuma yana lalata karfin methotrexate ga protein din.

Tare da haɗuwa da acetylsalicylic acid tare da maganin anticoagulants (coumarin, heparin) da magungunan thrombolytic, haɗarin zub da jini yana ƙaruwa saboda aikin platelet mara nauyi da lalacewar mucosa.

Yana rage tasirin anticoagulant na abubuwan gado na coumarin.

Sakamakon haɓakawar juna yayin da ake amfani dashi a cikin haɗaka tare da babban allurai (3 ≥ g / day) na wasu NSAIDs waɗanda ke ɗauke da salicylates, haɗarin ciwon raunuka da zubar jini na ciki na ƙaruwa.

Haɗin maganin acetylsalicylic acid tare da zaɓin inhibitors na serotonin reuptake (SSRIs, SSRIs) yana ƙara haɗarin zubar jini a cikin babban jijiyoyin ciki saboda tasirin tasirin cutar.

Acetylsalicylic acid yana ƙara maida hankali ga narkewa a cikin jini na jini.

Babban allurai na acetylsalicylic acid suna inganta tasirin hypoglycemic na magungunan antidiabetic (insulin, shirye-shiryen sulfonylurea) saboda tasirin hypoglycemic na acetylsalicylic acid da kuma kwararar ƙwayoyin sulfonylurea daga ƙwayoyin plasma.

Tare da yin amfani da acetylsalicylic acid a allurai ≥ 3 g / rana tare da diuretics, ana lura da raguwa a cikin matattara na duniya (saboda raguwa a cikin aikin prostaglandins da kodan).

Tsarin glucocorticoids (banda hydrocortisone, wanda aka yi amfani dashi azaman maganin maye don cutar Addison) yana rage yawan haɗarin salicylates a cikin jini, wanda ke kara haɗarin yawan tasirin salicylate bayan dakatarwar maganin glucocorticosteroid.

A bango na hadewar amfani da acetylsalicylic acid a allurai ≥ 3 g / rana da kuma inhibitors na angiotensin-mai sauya enzyme (ACE), an lura da raguwa a cikin ɗayan abubuwan ƙira na ACE inhibitors, wanda ke tattare da raguwa a cikin tasirin antihypertensive.

Acetylsalicylic acid yana haɓaka sakamako mai guba na valproic acid saboda ƙaura daga jihar da ke ɗaure abubuwan gina jiki.

Alcohol yana ƙaruwa lokacin zubar jini da kuma lahanta ɗan acetylsalicylic acid akan ƙwayar gastrointestinal.

Tare da yin amfani da haɗe tare da kwayoyi uricosuric (benzbromaron, probenicide), za a iya lura da raguwar tasirin uricosuric (saboda tsabtace guguwar uric acid ta hanta).

Umarni na musamman

Acetylsalicylic acid na iya tayar da hankali na asma ko wasu halayen rashin lafiyan. Abubuwan haɗari sune tarihin mai haƙuri na asma, zazzabin hay, polyposis na hanci, cututtukan numfashi, da halayen ƙwayar cuta ga wasu kwayoyi (alal misali, itching, urticaria, da sauran halayen fata).

Acarfin acetylsalicylic acid don murƙushe haɗarin platelet na iya haifar da zubar jini yayin da kuma bayan aikin tiyata (gami da ƙananan, kamar hakoran hakori). Hadarin zub da jini yana ƙaruwa tare da yin amfani da ASA a cikin babban kashi.

A karancin allurai, acetylsalicylic acid yana rage hakar uric acid, wanda zai iya haifar da ci gaba da gout a cikin marasa lafiya tare da farkon ayyukanta, wanda zai iya haifar da mummunan hari na gout a cikin marasa lafiya mai saukin kamuwa.

Kada a yi amfani da Acetylsalicylic acid wajen magance kamuwa da cuta, a gabanin ko rashin zazzabi, a cikin yara da matasa, ba tare da tuntubi likita ba. Tare da wasu cututtukan hoto ko bidiyo mai zagaya yanar gizo da sauri, musamman tare da mura A, ƙwayar cuta ta B da kuma kumburi, akwai haɗarin cutar Reye.

A cikin marasa lafiya tare da raunin glucose-6-phosphate dehydrogenase mai rauni, acetylsalicylic acid na iya haifar da cutar haemolysis ko hemolytic anemia.

Doseaya daga cikin kashi na miyagun ƙwayoyi ya ƙunshi 19 mg na sodium, wanda ya kamata a la'akari da shi ga marasa lafiya akan abincin da ba a iya cin gishiri.

Asfirin Tasirin yana dauke da tushen phenylalanine (aspartame), wanda zai iya zama cutarwa ga mutanen da ke fama da kwayar cutar phenylketonuria.

Siffofin tasiri na miyagun ƙwayoyi akan karfin tuka abin hawa ko ƙwararrun haɗari

Yawan abin sama da ya kamata

Bayyanar cututtuka: tsananin farin ciki, tinnitus, azanci na ji, ɗaci, ciwon kai, tashin zuciya, amai. Daga baya, zazzabi, hauhawar jini, ketosis, alkalanka na numfashi, acidosis na rayuwa, coma, rashin karfin jijiyoyin jiki, gazawar numfashi, rashin karfin jiki na iya bunkasa.

Jiyya: lavage na ciki, rubutaccen aikin gawayi da tilasta alkaline diuresis. Arin magani yakamata a gudanar dashi a sashin na musamman.

Yin hulɗa tare da wasu kwayoyi

Karatun na musamman yin karatu hulɗa da acetylsalicylic acid tare da wasu kwayoyi pSubconjunctival / parabulbar gwamnatin ba a yi shi ba. Tare da hanyoyin da aka ba da shawarar gudanarwa na tsarin kulawa da magunguna, ramuwar gayya game da hulɗa mara kyau tare da wasu kwayoyi ba zato ba tsammani. Wataƙila, yana yiwuwa a ƙara tasirin maganin heparin, magungunan anticoagulants na kai tsaye, reserpine, glucocorticosteroids da magungunan hypoglycemic na baka da raunana tasirin magungunan uricosuric. Tare da amfani da lokaci guda tare da methotrexate, haɓakar haɗarin sakamako na ƙarshen na iya yiwuwa.

Gudanarwa na Topical na lokaci guda tare da wakilai daban-daban na ophthalmic (a cikin nau'i na saukad da maganin shafawa) an yarda: glucocorticosteroids, tare da wakilai etiotropic (antiviral da / ko antibacterial therapy), antiglaucoma jamiái, m-anticholinergics, sympathomimetics, antiallergic kwayoyi. Tsakanin aikace-aikacen gida na ma'aikatan ophthalmic daban-daban, aƙalla mintuna 10-15 ya kamata su wuce. Bai kamata a yi amfani dashi tare da sauran NSAIDs ba a cikin gida (a cikin nau'ikan shigarwa ko injinar subconjunctival / parabulbar). Kada ku haɗo maganin da aka tanadar na acetylsalicylic acid tare da maganin wasu kwayoyi.

Halin lokaci guda na etiopathogenetic therapy (shan NSAIDs, antibacterial da antiviral therapy, glucocorticosteroids, antihistamines, da sauransu) an yarda.

Kariya da aminci

Kada ku haɗa maganin allura na miyagun ƙwayoyi tare da mafita daga wasu magunguna waɗanda ba a lissafta su cikin wannan umarnin ba. Pharmaceutically ya dace da procaine (a cikin sirinji ɗaya). Idan ya zama dole don rubanya acetylsalicylic acid lokaci guda tare da wasu magunguna don etiotropic da / ko Symptomatic therapy, aƙalla mintuna 10-15 ya kamata yai tsaka tsakanin amfani da jami'ai daban-daban na ophthalmic. Hanyar magani kada ta wuce kwanaki 10-12. Karka sanya suturar yayin jiyya ruwan tabarau.

Don rigakafin rikice-rikice na cututtukan ƙwayar cuta na ciki (musamman a cikin marasa lafiya da ciwon sukari mellitus), ana bada shawarar yin amfani da farkon angioprotector (dicinone, etamsylate, da sauransu).

Yin amfani da miyagun ƙwayoyi yana buƙatar taka tsantsan idan akwai matsala a cikin tsarin coagulation na jini da cututtukan jijiyoyi da cututtukan ƙwayar jijiyoyin ƙwayar hanji a cikin anamnesis saboda yiwuwar zub da jini. Tare da raunuka na ido mai lalacewa tare da lalacewar jikin ciliary, zubar jini yana yiwuwa. Acetylsalicylic acid ko da a cikin ƙananan allurai yana rage haɗarin uric acid daga jikin mutum, wanda zai iya haifar da haɓakar mummunan gout a cikin marasa lafiya mai saurin kamuwa. A lokacin magani ya kamata ya guji shan ethanol.

Tasiri kan iya tuƙin motoci da sarrafa hanyoyin masu haɗari: don marasa lafiya waɗanda hangen nesa ya ɓace na ɗan lokaci bayan shafawa ido, ba a ba da shawarar fitar da motoci ko yin aiki tare da hanyoyin motsa jiki na mintina kaɗan bayan ƙaddamar da maganin.