Kokarnit injections: koyarwa

Magungunan Kokarnit yana dogara ne akan bitamin da coenzymes, wanda ta hanyar aikin haɓakawa a cikin kyallen da ƙwayoyin jikin mutum ke inganta. Magungunan yana da sakamako kamar su neurometabolic da analgesic, kuma yana da tasiri mai kyau a cikin yanayin ciyayi na yanayi. Mene ne magani na Kokarnit, da kuma abubuwan da ake amfani da shi, za mu bincika a cikin kayan.

Aikin magani na magani

An gabatar da miyagun ƙwayoyi Kokarnit a cikin nau'i na hadaddun abubuwa na rayuwa da bitamin na ƙungiyoyi daban-daban. Abun da ke cikin miyagun ƙwayoyi Kokarnit ya ƙunshi irin wannan abu kamar nicotinamide, wanda yake hadaddun bitamin wanda tsarinsa ya kusanci acid nicotinic. Ta hanyar wannan abu, ayyuka masu zuwa sun bayyana:

• Ofarfafa ayyuka na redox a cikin sel jikin mutum da kyallen takarda.
• Sai dai itace da inganta nitrogen metabolism.
• Matsayi na atherogenic lipoproteins da ke cikin jini ya ragu.
• An kafa tasirin rigakafi.

Cocarboxylase yana cikin magungunan Kokarnit shine coenzyme daga wani rukuni na enzymes da ke hade cikin jiki. Irin wannan enzymes suna da mahimmanci a cikin tsarin carbohydrate da mai metabolism, kuma a Bugu da kari, inganta haɓaka glucose, daidaita yanayin jigilar abubuwan haɗin gwiwa da wadatar kyallen ɗan adam. Idan irin wannan enzyme a cikin jiki kamar cocarboxylase bai isa ba, to akwai karuwa mai yawa a matakin acid da lactate a cikin jini. Wannan yana haifar da ci gaban daidaiton ma'aunin acid.

An gabatar da Cyanocobalamin a matsayin abinci mai gina jiki wanda ya ƙunshi cobalt. Don aikin al'ada na jikin mutum, wannan sashin binciken na tilas ne. Da yawa daga cikin manyan ayyuka sun hada da:

1. Kasancewa mai aiki a cikin furotin, mai da kuma metabolism metabolism. Kari akan haka, bangaren gano abu yana kara habaka tsari a cikin kyallen.
2. Yana rage alaƙar cholesterol a cikin jini, kuma yana kawar da yawan ƙwayar kitse a hanta.
3. Yana da tasiri mai kyau akan aikin hanta da tsarin juyayi.

Wani muhimmin abu wanda ya haifar da Kokarnit shine adodiosine disodium. Kyakkyawan kaddarorin sun haɗa da:

• Rage saukar karfin jini.
• Yana faɗaɗa jijiyoyin jini.
• Yana rage abin da ya faru na arrhythmias.

Magungunan Kokarnit yana samuwa ne azaman allura don injections. Tana da launi mai launi na ruwan hoda, wanda ya kamata a narkar dashi kafin alurar riga kafi. Kit ɗin yana tare da sauran ƙarfi, har ma da umarnin don amfani. Abubuwan da ke cikin wadataccen magani suna ba ku damar samar da tasirin warkewa akan mutum tare da cututtuka daban-daban. Abin da cututtuka ake amfani da magani, muna ƙara koyon abubuwa.

Alamu don amfani

An wajabta allurar Kokarnit don amfani a gaban kowane ɗayan cututtukan masu zuwa:

• Cututtukan jijiya na yanayi mai kumburi.
• Muscle inna.
• Ciwan tsoka.
• Cutar bayyanar cututtuka, ya bayyana sakamakon matsi na jijiyoyin bugun gini.
• Sharp ƙananan ciwon baya.
• Cutar zuciya.
• Tsarin kumburi wanda yake haɓaka a cikin ƙwayar zuciya.

A gaban ɗayan cututtukan da ke sama, zaku iya komawa ga amfani da miyagun ƙwayoyi Kokarnit, amma kawai bayan alƙawarin ƙwararren masani ko tattaunawa tare da shi. Kuna iya ba da allurar Kokarnit a gida, idan a lokaci guda akwai isasshen matakin ilimi da aiki don aikin.

A cikin wane yanayi ne amfanin Cocarnit contraindicated

Umarni don amfani da Kokarnit ya bayyana cewa gabatar da rigakafin haramunne a lokuta idan mai haƙuri yana da cututtuka masu zuwa:

• bugun zuciya
• m zuciya,
• infarction na zuciya
• bugun jini
• asma,
• ƙari kansa neoplasms,
• kumburin ciki,
• ciwon sukari

Yin amfani da miyagun ƙwayoyi yana contraindicated idan mai haƙuri yana da tabbataccen sakamako na jiki ga kowane ɓangaren miyagun ƙwayoyi. Don ware haɓakar halayen rashin lafiyan, ana buƙatar gwaji na farko. Bugu da kari, likitoci ba su ba da shawarar neman taimako daga wannan magani ga mata a lokacin haihuwar yaro, da kuma lokacin shayarwa. Idan akwai buƙatar yin amfani da maganin yayin shayarwa, to ya kamata a canja ɗan jariri na ɗan lokaci don ciyar da wucin gadi.

Siffofin amfani da maganin

Abun da ke cikin miyagun ƙwayoyi Kokarnit ya haɗa da irin wannan bangaren kamar lidocaine. Kafin fara amfani da maganin, ya zama dole a tabbata cewa mara lafiyar ba shi da rashin lafiyar. Idan amsa ga abun da ke cikin miyagun ƙwayoyi ya kasance tabbatacce, to ya kamata a cire gabatarwar miyagun ƙwayoyi.

Yana da mahimmanci a sani! Idan wata alerji ta faru, alamomi irin su kumburi, jan fata, fitsari, saurin numfashi, da tabarbarewar yanayin lafiya. Hadarin bayyanuwar rashin lafiyar shine cewa magani na iya tayar da girgiza ƙwayar cuta, tare da haɓaka wanda mutum zai mutu.

Magungunan an yi shi ne kawai don gudanarwar wucin gadi. Kafin aiwatar da maganin, ya kamata ku buɗe ampoule tare da sauran ƙarfi, sannan ku buga adadin da ake buƙata a cikin sirinji, sannan ku ƙara shi cikin cakuda busasshen maganin. Bayan an ƙara maganin a cikin kwalbar tare da cakuda bushe, ba kwa buƙatar cire sirinji tare da allura daga kwalba. Abubuwan da ke cikin magani yakamata a haɗe sosai har sai an sami daidaito ɗaya, sannan a sa su a cikin sirinji.

Kafin saka maganin a cikin tsoka, shafin allurar ya kamata a kula da shi da barasa. Za'a iya sanya allura a cikin gluteus, amma ana buƙatar dogon allura don isa ga tsokoki na tsoka kai tsaye. Ana amfani da maganin a hankali don ware samuwar compaction a cikin kauri na tsopose nama.

Adadin yau da kullun na gudanar da maganin bai kamata ya wuce 4 ml ba, wato, ampoules biyu. Tsawon lokacin kawar da alamun jin zafi na iya wuce kwanaki 9, amma babu ƙari. A kowane yanayi, kuna buƙatar tuntuɓi ƙwararrun likita wanda zai ba da takamaiman yanayin aikace-aikacen irin wannan magani. Idan kayan aikin ba su ba da gudummawa ga bayyanar abubuwa masu tasiri ba, to likita ya yanke shawara game da nadin ƙarin magunguna masu ƙarfi.

Yawan overdose da sakamako

Mai sana'anta ba da shawarar gudanar da maganin a cikin adadin da ya fi abin da aka nuna a umarnin. Yawancin magunguna ba zai inganta yanayin mai haƙuri ba. Kuma hakan zai taimaka wajan haifar da wani sakamako na yawan zubar karfin jini. Bayyanar cututtuka na yawan zubar da jini suna faruwa ne saboda ci gaban waɗannan alamun:

• abin da ya faru na ciwon kai
• tsananin farin ciki
• gajiya,
• asarar sani
• na huhun ciki,
• asfaksiya
• rage karfin jini
• rage ji da gani,
• coma.

Idan, bayan gudanar da maganin, ɗayan alamun bayyanar da ke sama ya faru, yana da matukar mahimmanci ka dakatar da amfani da Cocarnit kuma kira don kulawa ta gaggawa. Magungunan rigakafin cutar Kokarnit ba ya wanzu, saboda haka, za a ba da taimakon da ya dace ga mai haƙuri dangane da alamuran da ke tashi.

Hanyoyi masu mahimmanci don amfani da magani

Bayan shiri na magani, ya kamata a yi amfani da allurar nan da nan. Adana tsawon lokaci na magungunan da aka shirya suna rage tasirin sakamako mai kyau. Bayan shirya allura, launinta ya kamata ja. Idan, bayan shiri, launin allura bai dace da ƙa'idar ba, to, haramun yin amfani da samfurin. Awararren ma'aikaci ne kaɗai ake buƙata don gudanar da magani, amma idan akwai ilimin da ya dace daga ƙwarewa, ƙaddamar da maganin an yarda wa mutum ba tare da ilimin likita ba (dangi ko aboki na mai haƙuri).

Kafin gabatarwar maganin, ya zama dole don shafa fata a wurin allurar. Tare da tsananin taka tsantsan, wajibi ne don amfani da miyagun ƙwayoyi a cikin irin waɗannan yanayi:

• m zuciya,
• cututtuka na tsarin numfashi
• zamani bayan aiki
• barasa
• koda mai aiki da hanta,
• hauhawar jini.

Yin amfani da miyagun ƙwayoyi a kowane ɗayan yanayi na sama na iya haifar da mummunan sakamako. Idan kayi amfani da maganin na dogon lokaci, to ba a cire cigaban cututtukan hanta na hanta ba. Don keɓance samuwar wannan nau'in rikitarwa, lokacin da aka tsara yin amfani da miyagun ƙwayoyi na kwanaki 9, ya kamata a shigar da abincin da ke wadatar cikin methionine a cikin abincin.

Idan ana gudanar da magani tare da taimakon Kokarnit, yakamata a sanya mahimmancin alamomin masu zuwa ba tare da lalacewa ba:

1. Matsayin glucose.
2. Potassium da magnesium a jiki.
3. Koma cikin jini.

Ga masoya kofi, ya kamata ku rage yawan amfani da shi yayin amfani da miyagun ƙwayoyi zuwa ƙarami.

Yin hulɗa tare da wasu magunguna

Ya kamata a ba da mahimmanci mai mahimmanci ga irin wannan ma'amala kamar hulɗa da miyagun ƙwayoyi tare da wasu kwayoyi. Mai ƙera da ƙwararru ba su bada shawarar yin amfani da Kokarnit tare da wasu nau'ikan kwayoyi ba, saboda wannan yana ba da gudummawa ga abubuwan da ke biyo baya:

1. Riskarin hadarin hauhawar hyperkalemia. Irin wannan ilimin yana haɓaka idan an dauki magani na haɗin gwiwa tare da diuretics.
2. Amfani da hadaddun glycosides yana ba da gudummawa ga faruwar cutar, kazalika alamu na gefe na tsarin zuciya.
3. Rage yawan lidocaine a cikin jini na jini ta hanyar haɗin Petidine da Quinidine.
4. Tare da yin amfani da morphine a hade, yana yiwuwa a tsokani hana aikin aikin numfashi.
5. Riskara hadarin zubar da jini idan an haɗaka da maganin cututtukan jini.
6. Haɗin kai tare da inhibitors yana taimakawa rage karfin jini.
7. Ba za ku iya amfani da Cocarnit tare da Xanthinol ba, tun da ƙarshen ƙarshen yana rage tasiri na tsohon.

Yana da mahimmanci a sani! Kafin gudanar da maganin, zaku iya tuntuɓar ƙwararren likita wanda zai gaya muku buƙatar amfani dashi.

Farashi da sifofin ajiya

Kuna iya siyan magungunan Kokarnit kawai saboda dacewa da ya dace daga likitan ku. Kudin maganin a cikin injections shine 720 rubles don ampoules 3. Masana'antu da yawa ne ke samar da maganin, saboda haka manufofin farashi na iya bambanta sosai. Don kada ya faɗi don karya, yakamata ku sayi magunguna na musamman a cikin kanannun magunguna.

Cire maganin kawai a cikin wani wuri mai duhu inda isa ga yara yana iyakance. Amfani da ingantaccen ƙwayar zai sanya mara amfani, bayan haka an haramta yin amfani da shi sosai. Yawancin lokaci, rayuwar shiryayye na miyagun ƙwayoyi daga ranar fitowa shine shekaru 3 tare da adana ta dace. Lokacin sayen magani, tabbata cewa ka kula da ranar saki. Bayan ranar karewa, maganin yana cikin zubar dashi.

Yana da mahimmanci a sani! Yin amfani da Cocarnitus yana contraindicated ga yara waɗanda shekarunsu bai kai shekara 18 ba.

A ƙarshe, ya kamata a lura cewa miyagun ƙwayoyi suna da analogues, don haka idan bai bayyana a cikin kantin magani na Kokarnit ba, to ana iya maye gurbin sa da: Cardonate, Actovegin, Vitaxone, Milgamma.

Form na sakin, kayan magani da kayan sa

A wace hanya ake sayar da maganin Kokarnit? Koyarwar ta ba da rahoton cewa wannan magani yana cikin nau'in lyophilisate don shirya mafita, kazalika da sauran ƙarfi (lidocaine) a cikin ampoules.

Abun da ke tattare da wannan wakili ya hada da nicotinamide, cocarboxylase, cyanocobalamin da adenosine triphosphate. Kamar yadda ake amfani da ƙarin abubuwan haɗin glycine, propyl parahydroxybenzoate da methyl parahydroxybenzoate.

Abubuwan harhada magunguna

Menene kayan aikin da muke la'akari? Me koyarwar za ta ce game da shi? Kokarnit wani hadadden bitamin ne da abubuwa wadanda ke shafar metabolism. Yana da tasirin neurometabolic da analgesic, kuma yana shafar yanayin motsa rai-da ciyayi.

Effectivearfin wannan magani ya faru ne saboda haɗinta. Yi la'akari da fasalin kowane ɗayan abubuwan a cikin ƙarin daki-daki.

Nicotinamide yana da tasiri sosai a kan ƙwayar carbohydrate da metabolism, yana ɗaukar matakai a cikin ayyukan sake fasalin, kuma yana inganta jigilar jigilar ATP a cikin sel. Hakanan, wannan kayan yana da kayan magani. A wannan batun, yana da matukar tasiri ga rikicewar neuropsychiatric, ɓacin rai, damuwa da rage kulawa.

Cocarboxylase wani coenzyme ne wanda ke taka rawa sosai a tsarin metabolism, yana shafar hadaddun kwayoyin nucleic, inganta trophism na kyallen, lipids da sunadarai, sannan kuma yana inganta shaye-shayen glucose.

Adenosine triphosphate asali ne na adenosine. Wannan bangaren yana motsa metabolism. Shine babban mahimmin makamashi na sel. Tare da cutar na jijiyoyin zuciya, karancin makamashi yana haɓaka, wanda za'a iya rage shi saboda adenosine triphosphate. Jigilar jigilar kwayoyin jikinta na faruwa ne sakamakon nicotinamide. Adenosine triphosphate yana da ikon yin amfani da maganin cutar huhu, cututtukan huhun jiki da illa.

Amma ga cyanocobalamin, yana tattarawa kuma yana tara sunadarai, yana motsa metabolism na carbohydrates da fats. Sakamakon wannan mataki shine raguwar cholesterol, da kuma hana haɓakar hepatosis.

Hakanan ya kamata a lura cewa cyanocobalamin yana ƙara ƙarfin farfadowa daga sel, wanda ya zama dole don aiki gabobin da ke cikin jini, hanta da tsarin juyayi.

Wadanne cututtukan ne aka rubuta irin wannan magani kamar su Kokarnit? Umarnin don amfani (injections yakamata ayi ta ƙwararrun masanin lafiya) ya nuna cewa alamun kayan aikin sune:

• neuritis
• neuralgia na asali iri-iri,
• sciatica, lumbago, sciatica,
• myalgia, tendonitis, bursitis,
• neuropathy (ciki har da ciwon sukari),
• myocardiopathy, cututtukan zuciya na ischemic, myocarditis.

Ya kamata kuma a faɗi cewa a lokacin daukar ciki ana amfani da wannan maganin ne kawai idan fa'ida ga uwar da ke gaba ta fi ƙarfin haɗari ga tayin.

Contraindications

Yaushe bai kamata ku rubuta magungunan "Kokarnit" ba? Umarnin ya ce wannan magani yana cikin hanyar:

• yawan tashin hankali
• mai tsananin nau'in hauhawar jini, da tashin zuciya,
• karin magana, erythremia,
• psoriasis
• take hakkin hanya da kuma rauni a zuciya,
• karancin cikar ciki a cikin lokacin m.

Ba shi yiwuwa a faɗi cewa likitan da ke cikin tambaya yana ba da shawarar a hankali ga mutanen da ke da cututtukan gastritis, cututtukan fata, gout da lalata hanta. Babu bayanai game da amfani da wannan magani a cikin ƙananan yara.

Bugu da kari, lokacin da ake rubuta magungunan da aka ambata, ya kamata a kula da contraindications masu zuwa na narkewa a cikin hanyar 0ido% lidocaine: Adams-Stokes syndrome, sinus node syndrome, angina pectoris, Wolf-Parkinson-White syndrome, myasthenia gravis, cututtukan cututtukan da ke da alaƙa da lidocaine mai tsanani gazawar koda da porphyria.

Kokarnit injections: koyarwa

Reviews game da wannan kayan aiki za a bayyana a kasa.

Dangane da umarnin, dole ne a gudanar da wannan magani ta intramuscularly a cikin ampoules 1 ko 2 kowace rana. Ana yin allurar ne a cikin darussan. Lokacin su ya dogara da tsananin cutar.

Ana amfani da maganin maganin kai tsaye bayan shiri. Haka kuma, yakamata ya zama ja. Idan launi bai canza ba, to, an haramta amfani da maganin.

Amfani da magani na Kokarnit, koyarwar wacce aka lullube ta cikin wani kwali na kwali, sel jini da platelet, lokacin sutura, uric acid, bilirubin da transaminases ya kamata a sa ido akai-akai

Side effects

Menene mummunan sakamako bayan amfani da Kokarnit? Umarnin yin amfani da shi yana nuna cewa wannan ƙwayar na iya haifar da:

• samarin
• ciwon kai
• cututtukan mahaifa
• rauni
• gumi
• tsananin farin ciki
• fata rashes,
• anaphylactic shock,
• itching
• zawo
• na gefe na jijiyoyin bugun jini,
• huhun ciki.

Hakanan ya kamata a lura cewa marasa lafiya tare da tashin hankali kafin gabatarwar miyagun ƙwayoyi suna gudanar da gwajin intradermal.

Yawan shaye-shayen kwayoyi

Me zai faru da yawan shan magani na Kokarnit? Umarnin don amfani (injections yakamata kawai kwararre ne ya tsara shi) ya faɗi cewa idan an sha magani ba da gangan ba, to guba na iya faruwa, wanda ke bayyana ta fesa fata, ƙaiƙayi, tashin zuciya, ciwon kai, amai ko ƙwannafi.

Don maye da shan kwayoyi na kullum, haɓakar matakin uric acid da glucose, da kuma bayyanar ulcers a cikin duodenum, halaye ne.

Yin hulɗa tare da wasu magunguna

Shin zan iya amfani da maganin Kokarnit (injections) tare da wasu kwayoyi? Umarni ya ba da rahoton cewa cocarboxylase, wanda shine ɓangare na miyagun ƙwayoyi, yana da ikon haɓaka tasirin zuciya na glycosides na zuciya.

Amma game da nicotinamide, yana iya mallakar dukiyar anticonvulsant na magungunan antiepilepti (alal misali, Diazepam, Carbamazepine, Valproate).

Adenosine triphosphate tare da diuretics-sparing na potassium, shirye-shiryen potassium da masu hana ACE suna haifar da haɗarin hyperkalemia. Hakanan yana haɓaka aikin (antianginal) na nitrates da beta-blockers.

Lokacin ɗaukar magani tare da Dipyridamole, ana inganta tasirin vasodilating.

Xanthinol nicotinate yana rage tasirin adenosine triphosphate, kuma Carbamazepine, akasin haka, yana inganta tasirin sa.

A hade tare da "Theophylline" da maganin kafeyin an bayyana.

Rage shan magani yana ragewa ta hanyar shirye-shiryen potassium, cyanocobalamin aminoglycosides, magungunan antiepilepti, salicylates da Colchicine.

Ragewar cyanocobalamin an rage yayin shan tare da "Polymyxin", "Kanamycin", "Neomatsin" da "Tetracycline."

Cyanocobalamin bai dace da ascorbic acid, Riboflavin, Pyridoxine da gishiri na karafa masu nauyi ba.

Maganin hana daukar ciki na rage rage cyanocobalamin a cikin jini.

Cost da analogues

Nawa ne magani "Kokarnit"? Umarnin don amfani ba zai ba da amsar tambaya ba. Za ku iya samun sa a cikin kantin magani kawai. A matsayinka na mulkin, farashin wannan samfurin don ampoules uku ya bambanta tsakanin 120-150 rubles.

Menene zai iya maye gurbin maganin metabolism na Kokarnit? Umarnin, bita suna cewa babu alamun analogues na wannan magani. Don maye gurbin shi da irin wannan hanyar, kuna buƙatar tuntuɓi likita (galibi suna ba da shawarar Ismizhen, Venohepanol, Threw, Orcipol, Sterillium, Dioflan, Collomac, Chondrosamine, Endofalk, “ Secnidox ").

Yanzu kun san ka'idodin aikin miyagun ƙwayoyi "Kokarnit." Umurnai, analog na wannan magani an gabatar dasu a sama.

Mafi sau da yawa, ana amfani da wannan kayan aikin a cikin ilimin jijiyoyin jini, ƙirar zuciya da aikin neurosurgical. Masana sun lura cewa wannan maganin yana da ikon rage adadin zubarwar jijiya, tare da kawar da ciwon mara na vertebrogenic.

Ya kamata kuma a lura cewa miyagun ƙwayoyi da ake tambaya sun tabbatar da kanta a cikin hadadden kulawa da marasa lafiya da ke haifar da ƙwaƙwalwar lumbosacral radiculitis A wannan yanayin, dole ne a yi amfani da miyagun ƙwayoyi a cikin 2 ml a kowace rana don makonni 2-3.

Marasa lafiya ba su ba da rahoton sakamako masu illa tare da wannan magani ba.

Formaddamar da tsari da abun da ke ciki

Kokarnit yana samuwa a cikin nau'i na lyophilizate don shiri na mafita don gudanarwar intramuscular (i / m): taro mai ruwan hoda na ruwan hoda, bayan sake yin ruwan hoda bayyananne (187.125 mg kowane a cikin gilashin gilashin duhu, ampoules 3 tare da lyophilisate da ampoules 3 a cikin farin falle) 2 ml tare da sauran ƙarfi, a cikin kwali na kwali 1 fakitin).

Ampoule 1 ya ƙunshi:

• sinadaran masu aiki: cocarboxylase - 50 mg, cyanocobalamin - 0,5 mg, triphosadenine disodium trihydrate - 10 mg, nicotinamide - 20 mg,
• abubuwa masu taimako: propyl parahydroxybenzoate, glycine, methyl parahydroxybenzoate.

Maganin ƙarfi shine lidocaine hydrochloride, ruwa don allura.

Pharmacodynamics

Ayyukan Kokarnit ya faru ne saboda kaddarorin da aka zaba mahallan hadaddun abubuwa masu aiki.

Cocarboxylase shine coenzyme wanda aka samo daga nitamine (bitamin B₁) Abun hadewar enzyme na carbonxylase, wanda ke rikitar da kuzarin kazamar ma'amala da yankewar acid acid-keto. Yana kai tsaye yana rinjayar tushen acidic na nucleic, lipids da sunadarai. Yana inganta shaye-shaye na glucose, rage girman abubuwan lactic da acid na jiki a cikin jiki, inganta trophism na nama mai juyayi.

Trifosadenin asali ne na adenosine, yana da sikari, antiarrhythmic, hypotensive, sakamako na vasodilating. A ƙarƙashin tasirin ATP (adenosine triphosphoric acid), tsokoki masu santsi suna annashuwa, hawan jini (BP) ya ragu, kuma ingantattun jijiyoyi suna haɓaka. Yana taimakawa wajen haɓaka metabolism da samar da makamashi na kyallen takarda. An bayyana tasirin aikin jijiyoyin ciki har da kan jijiyoyin zuciya da jijiyoyin zuciya.

Cyanocobalamin - Vitamin B₁₂, wanda bayan shiga jikin ya juya zuwa nau'i biyu na coenzyme: 5-deoxyadenosyl cobalamin da methyl cobalamin. Methylcobalamin yana taka muhimmiyar rawa a cikin halayen halayen metaboline na purine da tushen tushen pyrimidine, alal misali, a cikin juyawa na homocysteine ​​zuwa methionine da S-adenosylmethionine. Rashin bitamin a cikin wannan sakamako ana iya rama shi ta hanyar methyltetrahydrofolate acid, sakamakon wannan akwai cin zarafin halayen folic metabolism. 5-deoxyadenosyl cobalamin yana da hannu a cikin amsawar ƙwayar carbohydrate da metabolism, kasancewa cofactor a cikin isomerization na L-methylmalonyl coenzyme A cikin succinyl coenzyme A. Rashin bitamin B₁₂ a cikin jiki yana haifar da take hakkin haɓakar ƙwayar myelin na neurons, yaduwar ƙwayoyin epithelial cikin hanzari da ƙwayar hematopoietic.

Nicotinamide - wani nau'in bitamin PP, yana ɗaukar matakai na sake sarrafawa a cikin tantanin halitta. Yana ba da izinin numfashi na nama, yana inganta metabolism da metabolism.

Pharmacokinetics

Bayan gudanar da aikin parenteral, trifosadenin ya shiga cikin sel gabobin. A can, an rushe shi cikin adenosine da phosphate inorganic tare da sakin makamashi. Abubuwan samfurori masu lalacewa suna haɗuwa cikin ATP resynthesis.

Cire cocarboxylase tare da gudanarwar i / m yana faruwa cikin hanzari a cikin jiki tare da shigar azzakari cikin farji. Cire kayan abinci na rayuwa wanda ke faruwa a cikin hancin koda.

Bayan gudanar da aikin i / m, cyanocobalamin yana hanzari kuma yana ɗauka cikakke. Isar da kyallen takarda ana aiwatar dashi ta hanyar transcobalamin I da II, wanda yake ɗaure cikin jini. 0.9% na maganin da aka gudanar yana ɗaukar sunadarai na plasma. Bayan gudanarwa na / m, matsakaicin maida hankali a cikin jini ya kai bayan awa 1. An tara shi a cikin hanta. An cire ta da bile daga hanta zuwa cikin hanji, inda kuma ta sake shiga cikin jini. Cire rabin rayuwar shine kwana 500. A cikin aikin koda na al'ada, 7-10% an kewaya ta cikin kodan kuma kusan 50% ta hanjin hanjin. Idan akwai rauni na aiki na koda, 0-7% ne kodan ya cire, kashi 70-100 - cikin hanji. Cyanocobalamin yana tsallake shingen mahaifa kuma cikin madara.

Rarraba nicotinamide a cikin dukkanin kyallen takarda yana faruwa da sauri, abu yana da ikon haye shingen mahaifa ya shiga cikin nono. Sakamakon metabolism a cikin hanta, an kirkiro nicotinamide-N-methylnicotinamide. Cire kayan yana faruwa ta hanjin kodan. Cire rabin rabin rayuwa shine kimanin awa 1.3.

Volumearancin rarraba shine kusan 60 l, jimlar zubar jini yana kusan 0.6 l / min.

Umarnin don amfani da Cocarnit: hanya da sashi

Thearshen maganin yana ƙaddara don allurar intramuscular (zurfi cikin ƙwayar gluteal).

Bayan haɗawa da lyophilisate tare da sauran ƙarfi, ƙarshen sakamakon ya kamata ruwan hoda. Idan launi na mafita bai dace ba, ba za a iya amfani da shi ba.

An shirya maganin don maganin sarrafa kai tsaye.

Kada a ajiye maganin da aka gama maganin!

Likita ya tsara tsawon lokacin jiyya da yawan kulawa da Kokarnit dangane da yanayin cutar da tsananin.

• ciwo mai zafi na polyneuropathy: ampoule 1 lokaci a rana, tsawon lokacin amfani don sauƙaƙa alamun bayyanar cututtuka shine kwana 9,
• m bayyanar cututtuka na polyneuropathy: 1 ampoule 1 lokaci a cikin kwanaki 2-3. Hens of treatment sun dogara da tsananin cutar kuma yana iya zuwa daga allura 3 zuwa 9 akan tsawon kwanakin 14-21.

Bukatar maimaita karatun shine likita ya ƙaddara.

Umarni na musamman

Idan mummunan halayen ya faru, nemi likita.

Tare da yanayin da ake faɗi na tasirin sakamako, yakamata a soke Kokarnit.

Idan bayan kwanaki 9 na amfani da miyagun ƙwayoyi babu wani magani mai warkewa ko cutarwar alamun cutar to an lura, yana da mahimmanci a yi la'akari da gyaran hanyar.

Yayin amfani da Kokarnit don isasshen iko na hanyar ciwon sukari mellitus, ya zama dole don daidaita sashin magungunan cututtukan jini.

Tasiri a kan ikon tuka motoci da abubuwa masu rikitarwa

Yayin aikin jiyya, yakamata a kula lokacin yin ayyukan haɗari. Marasa lafiya waɗanda ke ɗaukar Kokarnit suna haifar da tsananin damuwa, rikicewa ko wasu rikice-rikice na tsarin juyayi bai kamata su shiga cikin tuki motocin da inji ba.

Hulɗa da ƙwayoyi

Tare da amfani da magani na lokaci daya Kokarnit:

• hypoglycemic jami'ai dauke da metformin na iya shafar shan cyanocobalamin kuma zai iya rage raguwa a cikin jini,
• riboflavin, ascorbic acid, thiamine bromide, thiamine, salts karfe mai nauyi, pyridoxine, folic acid, wakilai na jini, chloramphenicol - ba za a iya amfani dashi ba saboda rashin jituwa tare da cyanocobalamin,
• aminoglycosides, magungunan antiepileptik, salicylates, colchicine, shirye-shiryen potassium yana rage yawan cyanocobalamin,
• dipyridamole yana haɓaka sakamako na vasodilating da kuma sakamakon trifosadenin,
• maganin kafeyin, theophylline (abubuwan da aka samo asali na purine) na iya haifar da wasu maganganu na adawa da maganin,
• babban allurai na glycosides na zuciya na iya kara hadarin sakamako mara amfani daga tsarin zuciya,
• xanthinol nicotinate yana rage tasirin maganin,
• antihypertensives da magunguna, magungunan kwantar da hankali a ƙarƙashin tasirin nicotinamide suna inganta tasirin warkewar su.

Analogues na Cocarnit sune Thiamine Chloride da Cocarboxylase.

Reviews game da Kokarnite

Bayan 'yan bita na Kokarnit suna ba da shaida ga ingancin ƙwayar a cikin maganin cututtukan ciwon sukari. Marasa lafiya da ciwon sukari suna rubuce game da saurin maganin, lokacin da ciwon kafa da radiculitis suka tafi bayan wasu jean allura. Babu koke game da rashin haƙuri mara kyau da kuma munanan abubuwan da suka faru yayin aikin jiyya.

Tunda abubuwan da ke cikin miyagun ƙwayoyi suna da kewayon warkewa mai yawa, sau da yawa akwai sake dubawa masu kyau game da marasa lafiya da ke amfani da miyagun ƙwayoyi don cututtukan cututtuka irin su osteochondrosis, cututtukan zuciya, neuralgia na lumbosacral kashin baya. Baya ga sakamako masu tasiri, an lura da haɓaka rayuwar kyautata lafiya da yanayin hanta. Magungunan yana rage karfin jini da cholesterol, yana da tasirin antiarrhythmic da sakamako na vasodilator.

Cocarnit a ampoules: fasali na miyagun ƙwayoyi

Kokarnit yana nufin - injections a cikin ampoules. Akwai kawai a cikin tsarin lyophilisate don allura. Babu a cikin kwamfutar hannu, dakatarwa, da sauran nau'ikan. Ya ƙunshi bitamin na rayuwa da abubuwa waɗanda ke taimakawa ga haɓaka metabolism.

Ayyukan maganin sun hada da:

• kunnawa na aiki da iskar shaka a cikin jiki,
• haɓaka aikin metabolism,
• alakar rigakafi,
• raguwa a cikin lipoproteins na atherogenic a cikin jini,
• vasodilation,

Magungunan suna kama da foda mai ruwan hoda, don allura zai buƙaci a iya narke shi. Magani don foda ya zo cikakke tare da magani a cikin kunshin ɗaya.

Kada kuyi ƙoƙarin tsarmar Kokarnit foda tare da "ingantattun abubuwa" - bi umarnin mai kyau, kuyi amfani da matattarar maganin da ƙungiyar masu ƙera magunguna ta gabatar.

Alamu don amfani da Cocarnit a cikin ampoules sun bambanta. Ana buƙatar tallafin metabolism don cututtuka daban-daban kuma yayin ayyukan dawo da jiki.

Idan kana buƙatar ƙarfafa metabolism, likitanka na iya tsara Cocarnit. Ba za ku iya “rubuta” shi da kanku ba.

Tallafin abubuwan wakili

Ana samar da tasirin tallafin jiki na miyagun ƙwayoyi ta hanyar daidaitaccen ma'adinai da bitamin. Ya ƙunshi abubuwa kamar:

• trifosadenin (10 mg),
• cocarboxylase (50 mg),
• cyanocobalamin (0,5 mg),
• nicotinamide (20 mg),
• 5-deoxyadenosylcobalamin,
• tsofaffi (ruwa, lidocaine, glycine).

Kowane abu a cikin abun da ke ciki yana aiwatar da aikinsa. Trifosadenin da cyanocobalamin suna haɓaka metabolism, kuma cocarboxylase yana taimakawa jiki ta hanyar samarda acid, sunadarai, lipids, inganta haɓakar glucose. 5-deoxyadenosylcobalamin shima yana da karfi a cikin halayen metabolism. Kuma nicotinamide yana da tasirin gaske akan kyallen takarda, kasancewa ɗaya daga cikin abubuwan da ake amfani da bitamin PP.

Yaya ake amfani da hadaddun Kokarnit

Daga cikin marasa lafiya da ke fama da radiculitis da ciwon tsoka, Cocarnit ya zama ruwan dare gama gari. Idan ciwo mai zafi yana magana sosai, ana gudanar da ampoule guda na miyagun ƙwayoyi ga mai haƙuri kowace rana (ana iya ƙara yawan sashi akan shawarar likita). Matsakaicin matsakaici bai wuce kwanaki 9 ba. Tsarma da foda kawai tare da maganin da ya zo tare da shi. Maganin yana da zafi, duk da lidocaine a cikin abun da ke ciki, amma raunin ƙwayar tsoka yana faruwa ne saboda maido da metabolism.

Matsakaicin warkewa na Kokarnit ya haɗa daga allura 3 zuwa 9 don rage yanayin mai haƙuri.

Idan ciwo mai rauni ba a furta haka ba, amma ya nuna kanta, an wajabta maganin a cikin adadin allurai 2-3 na ampoule guda ɗaya a mako don makonni 2-3.

Likita ne yake kula da hanyoyin kulawa. Zai fi dacewa a yi amfani da mutanen da kawai suka san yadda za su yi. Idan ku da ƙaunataccenku ba ku da ƙwarewar musamman, sai ku tuntuɓi wata ma'aikaciyar jinya a asibitin da ake yi wa magani, za ta taimaka wajen bayar da allura.

Irin kwayoyi

Analogues na miyagun ƙwayoyi, wanda aka kwatanta da irin wannan sakamako na warkewa, za'a iya amfani dashi idan ba zai yiwu ba don siyan Cocarnit (ko kuma akwai rikice-rikice da rashin haƙuri na mutum). Kuna iya bincika tare da likitan ku wanda magani ya dace muku azaman maye.

Daga cikin kwayoyi masu kama da wannan, zaku iya samun magunguna masu rahusa fiye da Kokarnit, wanda ampoules ɗin ya kai kusan 600 rubles. Amma akwai magunguna kuma sun fi tsada, amma a lokaci guda ingantacce ko dacewa musamman a batunku. Tattaunawa tare da likita kafin sayen irin waɗannan magunguna ana buƙatar.

Kokarnit injections

Hanyoyin haɓaka metabolism-Cocarnit (Cocarnit) ƙari kuma suna haɓaka jijiyoyin jijiyoyin jijiyoyin jiki. Kamfanin magani na Masar shine E.I.P.I.Co, ya kasance ga rukuni na wakilai na rayuwa dangane da hadadden abubuwan aiki na nicotinamide, cyanocobalamin, cocarboxylase da adenosine triphosphate.

Ampoules yana dauke da abubuwa masu aiki da taimako na gaba:

Foda mai ruwan hoda, bayani da aka shirya, m, m

Taro na trifosadenine disodium trihydrate, mg / ml

Cakuda cocarboxylase, mg / ml

Cakuda cyanocobalamin, mg / ml

Nicotinamide maida hankali, mg / ml

Karin kayan aikin abun hadewa

Glycine, methyl da propyl hydroxybenzoate

Ruwa, lidocaine hydrochloride

3 ampoules na 187 MG foda tare da ampoules 3 na abubuwan narkewa 2 ml a kowace fakiti

A lokacin daukar ciki

Likitoci na iya yin allurar rigakafin Kokarnit a yayin daukar ciki, in da a ce amfanin da ake tsammanin zai samu ga mahaifiyar fiye da hadarin da ke tattare da tayin. A wasu halaye, an haramta amfani da miyagun ƙwayoyi lokacin ɗaukar yaro. Lokacin shayarwa, an haramta amfani da maganin, saboda abubuwa masu aiki na abun da ke ciki sun shiga cikin madarar nono kuma suna iya cutar da jariri.

A lokacin ƙuruciya

Yin amfani da maganin yana contraindicated a cikin yara da matasa a kasa da shekaru 18 years. Wannan ya faru ne saboda gaskiyar cewa ba a gudanar da bincike kan tasiri da amincin amfani da miyagun ƙwayoyi a cikin wannan rukunin na zamani ba. Yin amfani da injections ba tare da izinin likita ba na iya haifar da halayen marasa kulawa daga tsakiya da na jijiyoyin jijiyoyi.

Analogues na Cocarnith

Babu wani tsarin analogues na miyagun ƙwayoyi dangane da abun da ya kunsa. Abubuwan da suka fi kusa da maganin sune:

• Thiamine chloride - wani nau'in kwayar bitamin B1, yana shiga cikin metabolism na cocarboxylase, yana sake cika raunin abu,
• Cocarboxylase - allura don aikin coenzyme da dukiyar da aka samar da metabolism din metabolism,
• Cardonate - capsules dangane da cocarboxylase,
• Vitaxone shine madadin magani na warkewa. Ana amfani dashi don kula da neuralgia.

Farashin Kokarnit

Kuna iya siyan Kokarnit a cikin Moscow ta hanyar magunguna ko shafukan yanar gizo. Kudin magungunan ya dogara da nau'in kantin magani da matakin iyakokin kasuwanci. Kimanin farashin kimar magunguna da misalinnunka zai kasance:

Kudin magunguna, rubles

Cocarnit, ampoules tare da sauran ƙarfi 3 + 3 ml

Thiamine hydrochloride 1 ml 10 ampoules

Cocarboxylase, 50 mg 5 ampoules

Margarita, 39 years old Mahaifiyata tana da radiculitis. Ba shi da sauƙi a sauƙaƙe jin zafi tare da allunan al'ada, saboda haka muna amfani da magani Kokarnit. Likitoci sun wajabta mana. Bayan allura a cikin tsokar gluteal, mahaifiyar ta ce ciwon raunin yana raguwa, zai zama da sauƙi a gare ta ta yi tafiya. Mafi mahimmanci, shiri na bitamin baya haifar da sakamako masu illa, an yarda da shi sosai.

Ruslan, yana da shekara 66. Kokarnit ya ba ni magani bayan an gano cutar neuralgia. An kifar da baya ta yadda ba zan iya tafiya ba, kowane motsi ya haifar da ciwo mai zafi. Likitoci sun zo gidana, sun ba da allura. Bayan allura biyu, ya zama mafi sauƙi a gare ni, kuma bayan karatun mako guda na shirya in yi gudu - Ba a ji rauni ni ba.

Vadim, yana da shekara 57. An gano cutar ciwon huhu a bara. Yana da wuya a yi aiki na yau da kullun - zuciyata ta sami rauni, ƙari, gajeriyar numfashi, matsalolin numfashi sun fara. Bayan tsananin cutar da cutar, na ƙare a asibiti. A can ne aka rubuta mini allura ta Kokarnit. Lokacin da allura da mafita a cikin buttock, yana da rauni, amma na jure shi saboda wannan sakamakon. Yayinda nake kan magani.

Cyanocobalamin

A cikin jini, cyanocobalamin yana ɗaure zuwa transcobalamin I da II, wanda ke jigilar shi zuwa kyallen. An adana shi musamman a cikin hanta. Sadarwa tare da ƙwayoyin plasma - 90%. Da sauri kuma gaba daya tuna bayan intramuscular da subcutaneous management. Matsakaicin maida hankali bayan allurar intramuscular ya samu bayan awa 1.

An cire ta daga hanta ta bile cikin hanjin ta kuma sake shiga cikin jini. Cire rabin rayuwar shine kwana 500. An cire shi tare da aikin koda na al'ada - 7-10% ta kodan, kusan 50% - ta hanjin hanji. Tare da rage yawan aikin koda - 0-7% ta kodan, 70-100% - ta hanji. Har ila yau, ya shiga cikin hanyar ƙwarin mahaifa zuwa cikin madara.

Nicotinamide

An rarraba shi da sauri a cikin dukkan masana'anta. Har ilayau, ta hanyar shinge daga cikin mahaifa kuma zuwa cikin madara. An metabolized a cikin hanta tare da samuwar nicotinamide-N-methylnicotinamide. Kodan ya fice.

Rabin rayuwar rabin plasma yakai kimanin sa'o'i 1.3, girman rarrabuwa a tsaye yakai kimanin lita 60, kuma jimlar kusan 0.6 l / min.

Sashi da gudanarwa

Magungunan an allurar dashi sosai (cikin jijiya mai gluteus).

A cikin lokuta mai raɗaɗi mai raɗaɗi, magani yana da kyau a fara da allura ta hancin 1 ampoule (2 ml) kowace rana har sai an sami sauƙin bayyanar cututtuka. Yawan amfani shine kwana 9.

Bayan haɓaka bayyanar cututtuka ko a lokuta na matsakaici bayyanar cututtuka na polyneuropathy: 1 ampoule sau 2-3 a mako don makonni 2-3. Hanyar da aka ba da shawarar yin magani shine 3 injections, dangane da tsananin cutar.

Tsawon lokacin magani da maimaita kwasa-kwasan likita ne ya danganta da yanayin cutar da cutar.

Yawan yawan bayyanar cututtuka

Trifosadenin: wucewa da matsakaicin adadin yau da kullun (game da 600 mg ga tsofaffi) na iya haifar da ci gaban bayyanar cututtuka masu biyo baya: rashin jin daɗi, raguwar hawan jini, asara na ɗan gajeren lokaci, arrhythmia, toshe na II da digiri na III, asystole, bronchospasm, damuwa na ventricular, sinus bradycardia da samarin

Cocarboxylase: Ana bayar da rahoton alamomin masu zuwa bayan gudanar da wani magani wanda ya fi sau 100 shawarar da aka ba da shawarar: spasm tsoka, rauni na tsoka, inna, arrhythmia.

Cyanocobalamin: bayan an gudanar da wani babban aiki, an lura da rikicewar fata na eczematous da wani nau'in cututtukan cututtukan fata. Lokacin amfani dashi a cikin allurai masu girma, yana yiwuwa haɓaka hypercoagulation, ƙwaƙwalwar ƙwayar tsarkakakkiyar ƙwayar jini.

Nicotinamide: lokacin amfani da manyan allurai, hyperpigmentation, jaundice, amblyopia, rauni, fashewar cututtukan peptic na ciki da duodenum. Tare da yin amfani da tsawan lokaci, haɓakar steatohepatosis, haɓaka haɗuwa da uric acid a cikin jini, an lura da rashin haƙuri na glucose.

An dakatar da gabatarwar miyagun ƙwayoyi nan da nan, an wajabta maganin cututtukan cuta, gami da juya hankali.

Yin hulɗa tare da wasu kwayoyi

A cikin marasa lafiya da ke amfani da wakilan hypoglycemic na rukunin biguanide (metformin), saboda rashi na cyanocobalamin daga jijiyar ciki, ana iya lura da raguwa a cikin cyanocobalamin a cikin jini. Tare da sauran wakilai na hypoglycemic, ba a bayyana ma'amala da magani ba.

Cyanocobalamin bai dace da ascorbic acid ba, gishiri na karafa mai nauyi, thiamine, nitamine bromide, pyridoxine, riboflavin, folic acid.

Ba za ku iya yin amfani da cyanocobalamin lokaci guda tare da kwayoyi waɗanda ke haɓaka coagulation na jini ba.

Bugu da kari, yakamata a guji yin amfani da cyanocobalamin tare da chloramphenicol.

Aminoglycosides, salicylates, magungunan antiepilepti, colchicine, shirye-shiryen potassium suna rage yawan cyanocobalamin.

Tare da haɗakar amfani da kwayoyi waɗanda ke ƙunshe da trifosadenin tare da dipyridamole, ana inganta tasirin dipyridamole, musamman tasirin vasodilating.

Dipyridamole yana haɓaka sakamako na trifosadenin.

An nuna wasu ƙiyayya ta hanyar amfani da miyagun ƙwayoyi tare da abubuwan ƙira na purine (maganin kafeyin, theophylline).

Ba za ku iya shiga lokaci guda tare da glycosides na zuciya a cikin allurai masu yawa ba, tunda haɗarin halayen gefen daga tsarin jijiyoyin jini ya ƙaru.

Tare da yin amfani da lokaci guda tare da xanthinol nicotinate, ana rage tasirin maganin.

Nicotinamide yana haifar da tasirin maganin hana maye, maganin kwantar da hankali, har ma da magungunan antihypertensive.