Protaphane® HM (Protaphane® HM)

Hypoglycemic wakili, matsakaici insulin.
Shiri: PROTAFAN® NM
Aiki mai guba na miyagun ƙwayoyi: isophane insulin din mutum
Lullukin ATX: A10AC01
KFG: Matsakaici Na Matsakaicin Humanan Adam
Reg. lamba: P No. 014722/01
Ranar rajista: 04/20/07
Mai mallaka reg. acc.: NOVO NORDISK A / S

Sakin tsari na Protafan nm, kayan magani da kayan hade.

Dakatarwar da aka yiwa sc kula da fararen launi, lokacinda aka sami sassauci, ya samar da farin farashi da mai launi ko kusan madaukaki mara nauyi, tare da motsa hankali, ya kamata a sake farfadowa.

1 ml
isofan insulin (injiniyan ɗan adam)
100 IU *

* 1 IU yayi daidai da μg na 35 na insulin na mutum.

10 ml - kwalabe na gilashin launi (1) - fakitoci na kwali.

LITTAFIN SAURARON SAUKI.
Duk bayanan da aka bayar an gabatar dasu ne kawai don fahimtar tare da miyagun ƙwayoyi, ya kamata ka nemi likita game da yiwuwar amfani.

Maganin ilimin magunguna na Protafan nm

Wakili na hypoglycemic, insulin na aiki-matsakaici wanda aka samo ta injiniyan kwayoyin, daidai yake da insulin ɗan adam.

Yin hulɗa tare da takamaiman mai karɓa akan membrane na sel, yana samar da hadaddun mai karɓar insulin. Ta hanyar haɓaka aikin cAMP (a cikin ƙwayoyin mai da ƙwayoyin hanta) ko kai tsaye shiga cikin sel (tsokoki), ƙwaƙwalwar mai ɗaukar insulin ɗin tana ƙarfafa ayyukan cikin ciki, gami da kira na enzymes masu yawa (ciki har da hexokinase, pyruvate kinase, glycogen synthetase).

Rage yawan haɗuwa da glucose a cikin jini shine lalacewa ta hanyar karuwa a cikin jijiyarsa, haɓaka sha da kwarjini da kyallen takarda, haɓakar lipogenesis, glycogenogenesis, ƙwayar sunadarai, da raguwa a cikin yawan samar da glucose ta hanta (rage raguwar glycogen).

Pharmacokinetics na miyagun ƙwayoyi.

Nunawa da farawa ya dogara da hanyar gudanarwa (sc ko intramuscularly), wuri (ciki, cinya, gindi) da girman allura, maida hankali ne akan insulin a cikin magunguna. An rarraba shi ba tare da daidaituwa ba a cikin kyallen takarda, ba ya shiga cikin shinge na mahaifa kuma zuwa cikin madara. An lalata shi ta hanyar insulinase, galibi a hanta da kodan. Kodan ya fitar da ita (kashi 30-80%).

Sashi da hanyar gudanar da magani.

Shigar s / c, sau 1-2 / rana, mintuna 30-45 kafin karin kumallo. Ya kamata a canza wurin allurar kowane lokaci. A cikin lokuta na musamman, gabatarwar a / m yana yiwuwa.

Ba a yarda da / a gabatarwar insulin na matsakaici ba

An sanya allurai daban-daban, gwargwadon abubuwan da glucose ya kunsa a cikin jini da fitsari, halayen hanyar cutar.

Tasirin sakamako na Protafan nm:

Harkokin halayen sakamakon tasirin metabolism: hypoglycemia (pallor na fata, karuwar gumi, palpitations, rawar jiki, yunwar, tashin hankali, paresthesia a cikin bakin, ciwon kai). Mai tsananin rashin ƙarfi na hypoglycemia na iya haifar da haɓakar ƙwaƙwalwar ƙwayar cuta.

Allergic halayen: da wuya - fatar fata, fitsarin Quincke, a wasu yanayi - tashin hankalin anaphylactic.

Abubuwan da suka shafi gida: hyperemia, kumburi, itching, tare da amfani mai tsawo - lipodystrophy.

Sauran: edema, kurakurai na yau da kullun kurakurai (yawanci a farkon farji).

Yi amfani da lokacin daukar ciki da lactation.

A lokacin daukar ciki, ya zama dole a la’akari da raguwar buƙatar insulin a cikin farkon farkon ko ƙaruwa a cikin na biyu da na uku. Lokacin kuma kai tsaye bayan haihuwa, buƙatun insulin na iya raguwa kwatsam.

Yayin shayarwa, ana buƙatar saka idanu kowace rana don watanni da yawa (har sai an daidaita buƙatar insulin).

Umarnin na musamman don amfanin Protafan nm.

Tare da taka tsantsan, ana aiwatar da zaɓi na miyagun ƙwayoyi a cikin marasa lafiya da cututtukan ƙwayar cuta na ƙwaƙwalwar ƙwayar cuta na baya wadanda suka kasance a cikin nau'in ischemic kuma tare da nau'ikan cututtukan zuciya masu rauni.
Buƙatar insulin na iya canzawa a cikin waɗannan lambobin: lokacin da canzawa zuwa wani nau'in insulin, lokacin da ake canza abinci, zawo, amai, lokacin canza yanayin da ya saba da aiki na jiki, a cikin cututtukan kodan, hanta, ƙwayar ƙwayar cuta, glandar thyroid, lokacin canza wurin allura.
Ana buƙatar daidaita daidaituwa na insulin ga cututtukan cututtukan, cututtukan thyroid, cutar Addison, hypopituitarism, gazawar koda, da kuma ciwon sukari a cikin marasa lafiya fiye da shekaru 65.

Canza haƙuri ga insulin ɗan adam ya kamata koyaushe a tabbatar da gaskiya kuma ana aiwatar da shi kawai a ƙarƙashin kulawar likita.

Abubuwan da ke haifar da rashin jini a cikin jiki na iya zama: insulin overdose, maye gurbin miyagun ƙwayoyi, tsallake abinci, amai, zawo, damuwa na jiki, cututtukan da ke rage buƙatar insulin (cututtukan koda da hanta, da hauhawar jini a cikin adrenal cortex, pituitary ko thyroid gland shine yake, canjin wurin allura) (alal misali, fata akan ciki, kafada, cinya), haka kuma ma'amala da wasu kwayoyi. Zai yiwu a rage taro na glucose a cikin jini yayin canja wurin mai haƙuri daga insulin dabbobi zuwa insulin ɗan adam.

Yakamata a sanar da mara lafiyar game da alamun cutar rashin haihuwa, game da alamun farko na rashin lafiyar masu cutar sankara da kuma game da bukatar sanar da likita game da duk canje-canje a yanayinsa.

Idan akwai matsalar hypoglycemia, idan mara lafiyar yana da hankali, an wajabta masa dextrose a ciki, s / c, i / m ko iv allura glucagon ko iv hypertonic dextrose. Tare da haɓakar ƙwayar ƙwayar cuta na jini, 20-40 ml (har zuwa 100 ml) na maganin 40% dextrose ana shigar da shi cikin rafi har sai mai haƙuri ya fito daga cikin warin.

Marasa lafiya da ciwon sukari na iya dakatar da ɗan ƙaramin ƙin jini na jini da suke ji ta wurin cin sukari ko abinci mai cike da ƙwayoyin carbohydrates (ana ba da shawarar marasa lafiya koyaushe a kalla 20 g sukari tare da su).

Rage shan giya a cikin marasa lafiya da ke karɓar insulin ya ragu.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Halin da ake samu na haɓaka hypoglycemia na iya lalata iyawar marasa lafiya don tuki motocin kuma suna aiki da hanyoyin.

Yin hulɗa da Protafan nm tare da wasu kwayoyi.

Tasirin hypoglycemic yana haɓaka ta hanyar sulfonamides (gami da wakilai na hypoglycemic na bakin, sulfanilamides), MAO inhibitors (ciki har da furazolidone, procarbazine, selegiline), inhibitors na carbonic anhydrase inhibitors, ACE inhibitors, ACE inhibitors, NSAIDs (gami da salicylides), anabolic (ciki har da stanozolol, oxandrolone, methandrostenolone), androgens, bromocriptine, tetracyclines, clofibrate, ketoconazole, mebendazole, theophylline, cyclophosphamide, fenfluramine, shirye-shiryen lithium, pyridoxine, quinidine, quinine, chlo, chlo, etin, chlo

Glucagon, somatropin, GCS, hana hana haihuwa, estrogens, thiazide da “madauki” diuretics, allunan tashar alli, hormones thyroid, heparin, sulfin pyrazone, sympathomimetics, danazole, tricyclic antidepressants, alli chloride, moron, rage sakamako hypogly sinadarin nicotine, phenytoin, epinephrine, blocor recepor blockers.

Beta-blockers, reserpine, octreotide, pentamidine duka zasu iya haɓaka da rage tasirin hypoglycemic na insulin.

Pharmaceutically bai dace da mafita da sauran magunguna ba.

Tsarin ilimin rayuwa (ICD-10)

Dakatarwa na gudanarwar subcutaneous1 ml
abu mai aiki:
insulin isophane (aikin injiniyan mutum)100 IU (3.5 mg)
(1 IU yayi daidai da 0.035 MG na insulin ɗan adam)
magabata: zinc chloride, glycerin (glycerol), metacresol, phenol, sodium hydrogen phosphate dihydrate, protamine sulfate, sodium hydroxide da / ko hydrochloric acid (don daidaitawa pH), ruwa don allura
Kwalbar 1 ta ƙunshi 10 ml na miyagun ƙwayoyi, wanda ya dace da 1000 IU

Protafan ® HM Penfill ®

Dakatarwa na gudanarwar subcutaneous1 ml
abu mai aiki:
insulin isophane (aikin injiniyan mutum)100 IU (3.5 mg)
(1 IU yayi daidai da 0.035 MG na insulin ɗan adam)
magabata: zinc chloride, glycerin (glycerol), metacresol, phenol, sodium hydrogen phosphate dihydrate, protamine sulfate, sodium hydroxide da / ko hydrochloric acid (don daidaitawa pH), ruwa don allura
Kayan 1 Penfill ® ya ƙunshi 3 ml na miyagun ƙwayoyi, wanda ya dace da 300 IU

Clinical Pharmacology

Tasirin yana inganta 1,5 hours bayan sc gwamnatin, ya kai matsakaici bayan sa'o'i 4-12 kuma yana ɗaukar awanni 24. Ana amfani da Protafan NM Penfill don ciwon sukari na insulin-insulin a matsayin basal insulin a hade tare da insulin-gajeran aiki, ga insulin-dogara-kamar na monotherapy , kuma a hade tare da insulins masu aiki da sauri.

Sashi da gudanarwa

Protafan ® HM Penfill ®

P / c. Magungunan an yi niyya ne don gudanar da aikin jinƙai na cikin ƙasa. Dakatarwar insulin ba za a iya shigar da / ciki ba.

An zaɓi kashi na miyagun ƙwayoyi daban-daban, la'akari da bukatun mai haƙuri. Yawanci, bukatun insulin tsakanin 0.3 da 1 IU / kg / rana. Bukatar yau da kullun don insulin na iya zama mafi girma a cikin marasa lafiya tare da juriya na insulin (alal misali, a lokacin balaga, har ma a cikin marasa lafiya tare da kiba), da ƙananan cikin marasa lafiya tare da ragowar insulin na insulin.

Ana iya amfani da Protafan ® NM duka a cikin monotherapy kuma a hade tare da insulin mai sauri ko gajere.

Protafan ® NM mafi yawanci ana gudanar dashi a ƙarƙashin cinya. Idan wannan ya dace, to ana iya yin allura a cikin bangon gaban ciki, a yankin gluteal ko kuma a cikin yanki na ƙwayar tsoka ta kafada. Tare da gabatarwar miyagun ƙwayoyi a cinya, akwai jan hankali a hankali fiye da lokacin da aka gabatar da shi zuwa wasu yankuna. Idan allurar tayi cikin yanki mai yaduwa da fata, za a rage girman hadarin da ke tattare da gudanar da maganin ta hanyar ƙwayar cutar.

Dole ne allurar ta kasance a cikin fata na akalla awanni 6, wanda ke tabbatar da cikakken kashi. Wajibi ne a canza wurin allura a koyaushe a cikin yankin ilmin jikin don hana haɓakar lipodystrophy.

An tsara Protafan ® NM Penfill ® don amfani da tsarin allurar insulin Novo Nordisk da allurar NovoFine ® ko NovoTvist ®. Cikakken shawarwari don amfani da gudanar da maganin ya kamata a lura.

Cututtukan da ke haɗuwa, musamman masu kamuwa da cuta tare da zazzabi, yawanci suna ƙaruwa da buƙatar jikin mutum na insulin. Hakanan ana iya buƙatar gyaran gyaran jiki idan mai haƙuri yana da cututtukan ƙwayar cuta na koda, hanta, nakasasshen aikin adrenal, pituitary ko glandar thyroid. Buƙatar daidaitawa na iya faruwa yayin canzawar aiki na zahiri ko abincin da aka saba samu. Zai yiwu a buƙaci daidaitawa yayin canja wurin mai haƙuri daga nau'in insulin zuwa wani

Yawan abin sama da ya kamata

Kwayar cutar haɓakar hauhawar jini (gumi mai sanyi, guguwar bugun zuciya, rawar jiki, yunwar, tashin hankali, tashin hankali, ciwon kai, ciwon kai, rashin motsi, rashin motsi, magana da rashin hangen nesa, rashin ƙarfi). Babban tsananin rashin ƙarfi na iya haifar da rashi na ɗan lokaci ko na dindindin na aikin kwakwalwa, coma, da mutuwa.

Jiyya: sukari ko bayani na glucose a ciki (idan mai haƙuri yana sane), s / c, i / m ko iv - glucagon ko iv - glucose.

Farashin kuɗi a cikin kantin magunguna a Moscow

Goden jerinFarashin, rub.Magunguna
6736379.00
Zuwa kantin magani
333.00
Zuwa kantin magani

Bayanin da aka bayar akan farashin magunguna ba tayin sayarwa ko siyan kaya bane.
Bayanin an yi nufin kawai don kwatanta farashi a cikin kantin magunguna masu aiki waɗanda ke aiki daidai da Mataki na 55 na Dokar Tarayya "A Circulation of Medicines" wanda aka sanya ranar 12.04.2010 N 61-ФЗ.

Formaddamar da tsari da abun da ke ciki

Siffar sashi - dakatarwa don gudanarwa karkashin mulki: farar fata, lokacin da yake tsayawa a cikin wani ruwa mai launi mara launi da farin farashi, an sake farfadowa dashi (10 ml a cikin gilashin gilashi mara launi, kwalban 1 a cikin kwali na kwali).

Abubuwan da ke aiki: insulin-isophan (injinin ɗan adam), a cikin kwalba 1 - unitsungiyoyin ƙasa guda 100, wanda ya yi daidai da 3.5 mg na insulin ɗan adam.

Componentsarin abubuwan da aka haɗa: protamine sulfate, phenol, metacresol, sodium hydrogen phosphate dihydrate, glycerol, zinc chloride, sodium hydroxide da / ko hydrochloric acid, ruwa don yin allura.

Sashi da gudanarwa

Ana aiwatar da Protafan NM a ƙarƙashin ƙasa.

An zaɓi kashi ɗaya daban-daban dangane da bukatun mutum na haƙuri, yawanci shine 0.3-1 IU / kg kowace rana. Bukatar na iya zama ƙasa cikin marasa lafiya da ke haifar da aikin insulin na inshinin ƙarami ko mafi girma a cikin marasa lafiya da juriya na insulin (alal misali, cikin kiba da balaga).

Ana iya amfani da Protafan NM duka a matsayin magani guda kuma a hade tare da insulin mai sauri ko gajere.

A cikin yanayin yayin da ake buƙatar yin ilimin insulin mai zurfi, ana iya amfani da dakatarwar azaman insulin basal (injections da yamma da / ko da safe) a hade tare da insulin gajere ko mai saurin motsa jiki (allurar ta yakamata a haɗe da abinci). Idan yana yiwuwa a sami ingantaccen iko na glycemic, to, rikice-rikice na ciwon sukari yawanci suna bayyana daga baya, sabili da haka ya kamata mutum yayi ƙoƙari don inganta sarrafa metabolism, a hankali yana sarrafa matakin glucose a cikin jini.

Mafi yawanci ana gudanar da Protafan HM a cikin yanki a cinya. Hakanan zaka iya yin allura a cikin bangon baya na ciki, zuwa cikin yankin ƙararrakin kafa, ko cikin yankin gluteal. Koyaya, a farkon lamari, an lura da saurin shan ƙwayoyi.

Don rage haɗarin allurar intramuscular na bazata, ya kamata a yi allura a cikin ɗakkiyar fatar fatar. Don hana haɓakar lipodystrophy, ana bada shawara don canza wurin allurar a cikin yankin na anatomical.

A cikin marasa lafiya da ke fama da rauni na koda da aikin hepatic, an rage buƙatar insulin, saboda haka, ana buƙatar daidaita sashi na Protafan NM.

Ana iya gudanar da dakatarwar kawai tare da sirinji insulin tare da sikelin wanda zai baka damar auna adadin da ake buƙata a cikin raka'a aikin. Vials don amfanin kai kaɗai.

Kafin amfani da Protafan NM:

  • Duba marufin kuma tabbatar cewa an zaɓi nau'in insulin daidai,
  • Bada izinin magani don dumama zuwa zafin jiki a ɗakuna sannan sai kawai a haɗa abubuwan dakatarwa,
  • Don shafa mai murfin roba.

An haramta amfani da miyagun ƙwayoyi don amfani da waɗannan halaye masu zuwa:

  • A cikin famfo na insulin
  • Rashin kare kwalban ya ɓace ko ya sako
  • An adana maganin ba daidai ba ko an sanyaya shi,
  • Bayan haɗuwa, ƙwayar ba ta sake farfadowa (ba ta zama mai ɗaukar hoto da fari).

Maganin allura lokacin amfani da Protafan NM kawai:

  • Dama dakatarwa, don yin wannan, mirgine kwalban tsakanin tafin hannu (preheating da shi zuwa zazzabi dakin),
  • Don jawo iska zuwa cikin sirinji a cikin adadin wanda yayi daidai da adadin insulin da ake buƙata,
  • Ceaddamar da iska a cikin murfin ta sokin matashin roba da matsi mai sirinji,
  • Juya kwalban a gefe, samun kashi na insulin,
  • Cire allurar daga cikin murfin kuma cire iska daga sirinji,
  • Duba daidai gwargwado
  • Cike kai tsaye.

Hanyar allura lokacin amfani da Protafan NM a hade tare da insulin gajere-aiki:

  • Dage dakatarwa (kamar yadda aka bayyana a sama),
  • Lectara iska a cikin sirinji a cikin ƙarar daidai da adadin Protafan NM, saka shi cikin kwalban da ya dace ka cire allura,
  • Don jawo iska a cikin sirinji a cikin ƙarar daidai da kashi na insulin gajeran aiki (ICD), shigar da shi cikin kwalban da ya dace,
  • Juya kwalban a gefe kuma buga lambar ta ICD,
  • Cire allurar, cire iska daga sirinji ka bincika daidai gwargwadon adadin da aka tattara,
  • Saka allura cikin kwalbar tare da Protafan NM, juya kwalban a gefe kuma buga lambar da ake so,
  • Cire allura daga vial da iska daga sirinji, duba daidai gwargwadon adadin da aka tattara,
  • Nan da nan allura mai-insulin magani da gajeran aiki.

Ya kamata a tattara insulin koyaushe a cikin jerin da aka bayyana a sama!

Ka’idojin gudanar da magunguna:

  • Tare da yatsunsu biyu, ninka fatar jiki zuwa jiki, saka allura a cikin gindinta a wani kusurwa kusan 45 ° kuma sanya allurar a karkashin fata,
  • Bar allura a karkashin fata na akalla awanni 6 don tabbatar da cewa an sarrafa maganin sosai.

Side effects

Abubuwan da ke haifar da sakamako a yayin jiyya tare da Protafan NM yawanci suna dogaro ne kuma suna faruwa ne saboda aikin insulin. Abubuwan da suka fi dacewa da mummunar tasirin shine hypoglycemia, wanda yawanci yakan haɓaka yayin haɗuwa da yawan adadin insulin dangane da buƙatar shi. Zazzagewar cututtukan zuciya na iya kasancewa tare da asarar hankali da / ko rashi, wanda hakan ke haifar da illa ga aikin kwakwalwa har ma da mutuwa.

Matsaloli masu iya haifar da sakamako:

    Daga gefen tsarin rigakafi: akai-akai (> 1/1000, 5 11111 Rating: 5 - 1 kuri'a

Haihuwa da lactation

Babu ƙuntatawa game da amfani da insulin a lokacin daukar ciki, tunda insulin ba ya ƙetare shingen mahaifa ba.

Dukkanin hypoglycemia da hyperglycemia, wanda zai iya haɓaka cikin yanayin da aka zaɓa na rashin dacewa, yana kara haɗarin rikicewar tayin da mutuwar tayi. Ya kamata a sa ido ga mata masu juna biyu masu ciwon suga a duk lokacin da suke cikin ciki, suna buƙatar motsa jiki don inganta haɓakar glucose na jini, shawarwarin iri ɗaya sun shafi matan da ke shirin daukar ciki.

Bukatar insulin yawanci yana raguwa a farkon farkon ciki kuma sannu a hankali yana ƙaruwa a cikin na biyu da na uku.

Bayan haihuwa, buƙatar insulin, a matsayin mai mulkin, da sauri ya koma matakin da aka lura kafin daukar ciki.

Hakanan babu hani akan amfani da miyagun ƙwayoyi Protafan® NM yayin shayarwa. Gudanar da ilimin insulin ga mata yayin shayarwa bashi da haɗari ga jariri. Koyaya, yana iya zama dole a daidaita tsarin magunguna ta Protafan® NM da / ko rage cin abinci.

Yin hulɗa tare da wasu kwayoyi

Akwai kwayoyi da yawa waɗanda ke shafar buƙatar insulin.

Hypoglycemic sakamako na insulin inganta baka hypoglycemic jamiái, monoamine oxidase hanawa, angiotensin tana mayar enzyme hanawa, carbonic anhydrase hanawa, zabe beta-blockers, bromocriptine, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, kwayoyi lithium salicylates .

Tasirin hypoglycemic na insulin yana raunana ta hanyar hana hana haihuwa, glucocorticosteroids, hormones thyroid, thiazide diuretics, heparin, maganin tricyclic antidepressants, sympathomimetics, hormone girma (somatropin), danazol, clonidine, jinkirin alli tashar blockers, diafenin, diafenin.

Beta-blockers na iya rufe bayyanar cututtukan hypoglycemia da rage jinkirin dawowa bayan hypoglycemia.

Octreotide / lanreotide na iya haɓaka da rage buƙatar jiki ga insulin.

Barasa na iya haɓaka ko rage tasirin insulin. Rashin daidaituwa

Kada a kara insulin insulin a cikin hanyoyin magance jiko.

Siffofin aikace-aikace

Rashin isasshen kashi ko katsewa na magani, musamman tare da nau'in ciwon sukari na 1 na ciwon sukari, na iya haifar da haɓakar haɓaka.

A matsayinka na mulkin, alamun farko na cututtukan hawan jini suna bayyana a hankali, a cikin sa'o'i da yawa ko kwanaki. Bayyanar cututtukan hyperglycemia sun hada da ƙishirwa, yawan urination, tashin zuciya, amai, amai, redness da bushewar fata, bushe baki, rashin cin abinci, da kuma bayyanar ƙamshin acetone a cikin iska mai narkewa. Ba tare da magani da ya dace ba, hyperglycemia a cikin marasa lafiya da ke dauke da ciwon sukari na 1 na iya haifar da ketoacidosis mai ciwon sukari, yanayin da ke da haɗari mai mutuwa.

Hypoglycemia yana iya haɓaka idan an gudanar da wani babban adadin insulin dangane da bukatun mai haƙuri.

Ski abinci ko kuma wani mummunan aiki na jiki wanda ba a shirya shi ba zai iya haifar da rashin lafiyar jiki.

Bayan ramawa game da metabolism na metabolism, alal misali, yayin ƙarfafan ƙwayar insulin, alamu marasa lafiya waɗanda suka kasance alamu a gare su na iya canzawa - takaddama na hypoglycemia, game da abin da ya kamata a sanar da marasa lafiya. Alamun gargaɗi na yau da kullun na iya ɓacewa tare da dogon lokaci na ciwon sukari.

Canja wurin marasa lafiya zuwa wani nau'in insulin ko zuwa insulin na wani kamfanin yakamata a gudanar da shi kawai a karkashin kulawar likita. Idan kun canza maida hankali, masana'anta, nau'in, nau'in (insulin ɗan adam, analog na insulin na mutum) da / ko hanyar masana'anta, kuna iya buƙatar canza sashin insulin. Marasa lafiya da ke cikin jiyya tare da Protafan® NM na iya buƙatar canjin kashi ko karuwa da yawaitar allura idan aka kwatanta da shirye-shiryen insulin da aka yi amfani da su a baya. Idan daidaitawar kashi ya zama dole yayin canja wurin marasa lafiya zuwa jiyya tare da Protafan® NM, ana iya yin wannan riga tare da gabatarwar kashi na farko ko a farkon makonni ko watanni na far.

Kamar yadda sauran shirye-shiryen insulin, halayen zasu iya haɓakawa a wurin allurar, wanda ke bayyana ta hanyar jin zafi, redness, amya, kumburi, hematoma, kumburi da itching. Canza wurin allura a kai a kai a cikin yanki iri iri na jiki zai taimaka wajen rage alamun ko hana ci gaban wadannan halayen. Abubuwan da suka shafi yawanci yakan ɓace a cikin 'yan kwanaki zuwa makonni da yawa. A cikin halayen da ba a sani ba, dakatar da Protafan® NM na iya zama dole saboda halayen a wurin allurar.

Kafin tafiya tare da canjin yankin lokaci, mai haƙuri ya kamata ya nemi shawara tare da mai ba da lafiyarsa, kamar yadda sauya lokacin lokaci yana nufin cewa mara lafiya dole ne ya ci ya kuma gudanar da insulin a wani lokaci daban. Ba za a iya amfani da abubuwan insulin a cikin famfunan insulin ba.

Yin amfani da kwayoyi na lokaci guda na ƙungiyar thiazolidinedione da shirye-shiryen insulin

An bayar da rahoton maganganun ci gaban cututtukan zuciya na jijiya a cikin kula da marasa lafiya tare da thiazolidinediones a hade tare da shirye-shiryen insulin, musamman idan irin waɗannan marasa lafiya suna da abubuwan haɗari don haɓakar bugun zuciya na kullum. Wannan gaskiyar yakamata ayi la'akari dashi yayin rubuta magunguna hade tare da thiazolidinediones da shirye-shiryen insulin ga marasa lafiya. Tare da nadin irin wannan maganin haɗin gwiwa, ya zama dole don gudanar da gwaje-gwaje na likita na marasa lafiya don gano alamun da alamun cututtukan zuciya na rashin ƙarfi, hauhawar nauyi da kasancewar edema. Idan alamun cututtukan zuciya sun lalace a cikin marasa lafiya, tilas a dakatar da jiyya tare da thiazolidinediones.

Tasiri kan ikon tuka motoci da aiki da injinan abubuwa

Thearfin marasa lafiya su mai da hankali kuma ana iya rage ƙarfin tashin hankali yayin lalacewa, wanda zai iya zama haɗari a cikin yanayi inda waɗannan damar ke da mahimmanci musamman (alal misali, lokacin tuki motoci ko aiki tare da injuna da injuna). Ya kamata a shawarci marassa lafiya su dauki matakan hana ci gaban hauhawar jini yayin tuki. Wannan yana da mahimmanci musamman ga marasa lafiya da basu da cikakkun alamu na abubuwan ci gaban haila ko kuma fama da yawan cututtukan cututtukan zuciya. A cikin waɗannan halayen, yakamata a yi la'akari da dacewar tuki da yin irin wannan aikin.

Yanayin ajiya

Adana a zazzabi of 2 ° C zuwa 8 ° C (a firiji), amma ba kusa da injin daskarewa ba. Kar a daskare.

Ajiye kwalban a cikin kwali a kwali don kariya daga haske.

Don kwalban da aka bude: kar a ajiye a cikin firiji. Adana a zazzabi da ba ya wuce 25 ° C na makonni 6.

Ya kamata a kare Protafan should NM daga tsananin zafi da haske. Ayi nesa da isar yara.

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