DIAinstruction: zabi da allura don sirinji na alkalami
Insulin Lantus SoloStar kwatankwacin kwatancen hormone ne tare da tsawan lokaci, wanda aka yi niyya don maganin nau'in 1 da nau'in ciwon sukari na 2. Abubuwan da ke aiki da miyagun ƙwayoyi shine insulin glargine, ana samun wannan kayan ne daga Escherichiacoli DNA ta amfani da hanyar ma'adanar.
Glargin yana da ikon ɗaure wa masu karɓar insulin kamar insulin ɗan adam, don haka miyagun ƙwayoyi suna da duk abubuwan da suka dace na ilimin halittu a cikin hormone.
Da zaran cikin kitse na subcutaneous, insulin glargine yana haɓaka samuwar microprecipitate, saboda wanda adadin adadin kwayoyin zai iya shigar da jinin jini koda yaushe. Wannan kayan yana samar da ingantaccen bayanin hangen nesa mai santsi.
Siffofin magani
Wanda ya kirkirar maganin shine kamfanin kasar Sanofi-Aventis Deutschland GmbH. Babban abu mai amfani da miyagun ƙwayoyi shine insulin glargine, abun da ke ciki ya haɗa da kayan taimako a cikin tsarin metacresol, zinc chloride, glycerol, sodium hydroxide, hydrochloric acid, ruwa don yin allura.
Lantus shine bayyananne, ruwa mara launi ko kusan ruwa mara launi. Mayar da mafita don warware ƙananan aikin shine 100 U / ml.
Kowane katun gilashin yana da maganin mil 3 na magani; an ɗora wannan katangar a cikin murfin sirinji na SoloStar. Ana sayar da alkalan insulin biyar don sirinji a cikin kwali, kwalin ya haɗa da jagorar koyarwa don na'urar.
- Za'a iya siye magungunan da ke da kyakkyawan nazari daga likitoci da marasa lafiya a kantin magani kawai tare da takardar sayen magani.
- An nuna insulin Lantus ga mellitus-insulin-da ke fama da ciwon sukari a cikin manya da yara sama da shekara shida.
- Tsarin musamman na SoloStar yana ba da damar jiyya a cikin yara sama da shekara biyu.
- Farashin kayan haɗi na alkalami guda biyar da magani na 100 IU / ml shine 3 500 rubles.
Umarnin don amfani da miyagun ƙwayoyi
Kafin amfani da miyagun ƙwayoyi, ya kamata ka nemi likitanka, wani endocrinologist zai taimake ka ka zabi madaidaicin sashi kuma ya tsara ainihin lokacin allura. Insulin yana allurar subcutaneously sau ɗaya a rana, yayin da allurar take yin ta sosai a wani lokaci.
An shigar da miyagun ƙwayoyi a cikin ƙashin ƙarƙashin cinya na cinya, kafada ko ciki. Kowane lokaci ya kamata ku canza wurin allurar don kada haushi ya haifar da fata. Za'a iya amfani da maganin a matsayin magani mai zaman kanta, ko a hade tare da wasu magunguna masu rage sukari.
Kafin amfani da insulin Lantus SoloStar a cikin sirinji na alkalami don magani, kuna buƙatar gano yadda ake amfani da wannan na'urar don yin allura. Idan a baya ana yin aikin insulin tare da taimakon insulin aiki na dindindin ko na matsakaita, yawan kwalliyar yau da kullun na insulin basal yakamata a daidaita.
- Game da canji daga allura sau biyu na insulin-isophan zuwa allura guda daya da Lantus ya yi a cikin makonni biyu na farko, yakamata a rage kashi na rana na yau da kullun da kashi 20-30. Ya kamata a biya kason da ya rage ta hanyar kara yawan amfani da insulin gajere.
- Wannan zai hana ci gaban hauhawar jini a cikin dare da safe. Hakanan, lokacin sauya sheka zuwa sabon magani, ana kara samun amsa game da allura na kwayoyin lokacin. Sabili da haka, da farko, ya kamata a hankali kula da matakin sukari na jini ta amfani da glucometer kuma, idan ya cancanta, daidaita tsarin sashi na insulin.
- Tare da ingantacciyar ƙa'idar aiki na metabolism, wani lokacin hankali ga miyagun ƙwayoyi na iya ƙaruwa, a wannan batun, ya zama dole don daidaita tsarin sashi. Hakanan ana buƙatar canza sashi ana buƙatar lokacin da ake canza salon rayuwar masu ciwon sukari, haɓaka ko rage nauyi, canza lokacin allura da sauran abubuwan da ke ba da gudummawa ga farawar hypo-ko hyperglycemia.
- An haramta yin amfani da miyagun ƙwayoyi don gudanarwar cikin jijiya, wannan na iya haifar da haɓakar ƙuntataccen ƙwayar cuta. Kafin yin allura, yakamata ka tabbata cewa alkairin danshi mai tsabta ne kuma mai bakararre.
A matsayinka na doka, ana gudanar da insulin na Lantus a maraice, satin na farko na iya zama raka'a 8 ko fiye. Lokacin canzawa zuwa sabon magani, nan da nan gabatar da babban kashi yana da haɗari ga rayuwa, don haka yakamata a yi gyara a hankali.
Glargin fara aiki da sa'a guda bayan allura, a matsakaita, yana yin awowi 24. Koyaya, yana da mahimmanci a yi la’akari da cewa tare da babban sashi, tsawon lokacin da maganin zai iya kaiwa awa 29.
Kada insulin Lantus tare da wasu kwayoyi.
Side effects
Tare da gabatarwar wani sashi mai yawa na insulin, mai ciwon sukari na iya fuskantar cutar sikari. Kwayar cuta ta rikicewar jiki yakan fara bayyana kwatsam kuma yana haɗuwa da jin gajiya, ƙaruwa mai rauni, rauni, rage yawan damuwa, matsananciyar damuwa, tashin hankali na gani, ciwon kai, tashin zuciya, tashin hankali, da bushewa.
Wadannan bayyanannu yawanci alamu ne a cikin nau'ikan ji na yunwar, tashin zuciya, tashin hankali ko rawar jiki, damuwa, fatar jiki, bayyanar gumi mai sanyi, tachycardia, bugun zuciya. Mai tsananin rashin ƙarfi na hypoglycemia na iya haifar da lalacewar tsarin mai juyayi, don haka yana da mahimmanci a taimaka wa mai ciwon sukari cikin lokaci.
A cikin halayen da ba kasafai ba, mai haƙuri yana da rashin lafiyan jiyya ga ƙwayar, wanda ke haɗuwa da tasirin fata mai narkewa, angioedema, bronchospasm, hauhawar jijiya, girgiza, wanda kuma haɗari ne ga mutane.
Bayan allurar insulin, ƙwayoyin rigakafi zuwa abu mai aiki na iya ƙirƙirar. A wannan yanayin, ya zama dole don daidaita tsarin jigilar magunguna don kawar da haɗarin haɓakar hypo- ko hyperglycemia. Da wuya, a cikin masu ciwon sukari, dandano na iya canzawa, a lokuta da ƙarancin yanayi, ayyukan gani na wucin gadi ne sakamakon canji cikin abubuwan gani na tabarau na ido.
Yawancin lokaci, a cikin allurar, masu ciwon sukari suna haɓakar lipodystrophy, wanda ke rage jinkirin shan ƙwayoyi. Don kauce wa wannan, kuna buƙatar canza shafin allurar akai-akai. Hakanan, redness, itching, soreness na iya bayyana akan fatar, wannan yanayin na ɗan lokaci ne kuma yawanci yakan ɓace bayan kwanaki da yawa.
- Ba za a yi amfani da insulin Lantus tare da tashin hankali ga glargine mai aiki ko wasu abubuwan taimako na miyagun ƙwayoyi ba. An haramta amfani da miyagun ƙwayoyi don amfani a cikin yara 'yan shekaru shida, amma likita na iya ba da takaddama na musamman na SoloStar, waɗanda aka yi niyya ga yaran.
- Yakamata a yi taka tsantsan yayin aikin insulin yayin ciki da shayarwa. Yana da mahimmanci kowace rana don auna sukari na jini da sarrafa hanyar cutar. Bayan haihuwa, ya zama dole don daidaita sashi na maganin, tunda ana rage bukatar insulin a wannan lokacin.
Yawancin lokaci, likitoci sun ba da shawarar yayin daukar ciki tare da ciwon sukari don yin amfani da wani analog na insulin na dogon lokaci - maganin Levemir.
Game da yawan abin sama da ya kamata, an dakatar da matsakaiciyar jini ta hanyar daukar samfuran da suka hada da abubuwan carbohydrates cikin sauri. Bugu da ƙari, tsarin kulawa yana canzawa, an zaɓi abinci mai dacewa da aikin jiki.
A cikin hypoglycemia mai tsanani, ana gudanar da glucagon a cikin intramuscularly ko subcutaneously, kuma ana ba da allurar rigakafin ƙwayar glucose mai rauni.
Ciki har da likita na iya yin amfani da maganin carbohydrates.
Yadda ake yin allurar insulin
Kafin yin allura, kuna buƙatar bincika yanayin kabad ɗin da aka sanya a cikin alkairin sirinji. Maganin zai zama m, mara launi, ba dauke da laka ko abubuwan gani na waje, na ruwa mai daidaituwa.
Alkalami na syringe naura ne wanda za'a iya dashi, saboda haka, bayan allura, dole ne a zubar dashi, sake amfani da shi na iya haifar da kamuwa da cuta. Kowane allura ya kamata a yi tare da sabon allurar bakararre, don wannan dalili ana amfani da allura na musamman, waɗanda aka kera su don sirinji alkalami daga wannan ƙirar.
Dole ne a zubar da na'urorin da suka lalace, tare da ɗanɗanar shakkuwar cutarwar, ba za a yi allura tare da wannan alkalami ba. A wannan batun, masu ciwon sukari dole ne a koyaushe su sami ƙarin sirinji don maye gurbin su.
- An cire maɓallin kariya daga na'urar, bayan wannan alamar akan ɗakin insulin tabbas tabbas ana duba shi don tabbatar da cewa kyakkyawan shiri ya kasance. Ana kuma nazarin bayyanar mafita, a gaban laka, ƙwayar baƙin waje ko daidaituwar turbid, ya kamata a maye gurbin insulin tare da wani.
- Bayan an cire murfin kariya, allurar mai tazara a hankali kuma a haɗe take da alkalami na syringe. Kowane lokaci kuna buƙatar bincika na'urar kafin yin allura. Yana da mahimmanci a tabbatar da cewa dabino ya kasance da farko a 8, wanda ke nuna cewa ba'a yi amfani da sirinji ba kafin.
- Don saita adadin da ake so, maɓallin farawa an cire shi gabaɗaya, bayan wannan mai zaɓin kashi ba zai iya juyawa ba. Yakamata a cire murfin waje da na ciki, a kiyaye su har sai an gama aikin, domin bayan allurar, cire allurar da aka yi amfani da ita.
- Ana riƙe alkalami na syringe ta allura, bayan haka kuna buƙatar sauƙaƙe yatsunku a kan tafkin insulin don iska a cikin kumfa ta iya tashi zuwa allura. Bayan haka, ana danna maɓallin farawa koyaushe. Idan na'urar ta shirya don amfani, ƙaramin digo ya kamata ya bayyana a ƙarshen allura. Idan babu digo, ana sake maimaita siren syringe.
Mai ciwon sukari na iya zaɓar sashin da ake so daga raka'a 2 zuwa 40, mataki ɗaya a wannan yanayin shine raka'a 2. Idan ya cancanta, gabatarwar karin kashi na insulin, yi allura biyu.
A kan ma'aunin insulin na saura, zaku iya bincika yawan ƙwayar da aka bari a na'urar. Lokacin da piston na baƙin fata ya kasance a cikin farkon ɓangaren tsiri mai launin, adadin maganin shine 40 PIECES, idan an sanya piston a ƙarshen, kashi shine 20 PIECES. Ana za selectar mai za dosear kashi har sai maɓallin kibiya ya isa kashi da ake so.
Don cika alkalami insulin, an ja maɓallin fara allurar zuwa iyaka. Kuna buƙatar tabbatar da cewa an zaɓi miyagun ƙwayoyi a cikin sashi ɗin da ake buƙata. An canza maɓallin farawa zuwa gwargwadon adadin hormone da ya rage a cikin tanki.
Yin amfani da maɓallin farawa, masu ciwon sukari na iya bincika nawa aka tattara insulin. A lokacin tabbatarwa, ana kiyaye mabuɗin. Yawan adadin miyagun ƙwayoyi da aka ɗauka za'a iya yin hukunci da shi ta layin ƙarshe da aka gani.
- Dole ne mara lafiyar ya koyi yin amfani da allon insulin kafin lokacin, ƙwararrun aikin insulin dole ne su sami horo daga ma'aikatan kiwon lafiya a asibitin. Ana saka allurar koyaushe a ƙarƙashin subcutane, bayan haka ana danna maɓallin farawa zuwa iyaka. Idan an matsa maɓallin gabaɗaya, danna mai sauraro zai yi sauti.
- Ana riƙe maɓallin farawa har na 10 seconds, bayan haka za'a iya cire allura. Wannan dabarar allurar tana ba ka damar shigar daukacin maganin. Bayan an yi allura, sai a cire allura daga alkairin da aka zubar kuma ba za ku sake amfani da ita ba. Ana sanya hula mai kariya a allon alkairin.
- Kowane alkalami na insulin yana tare da littafin koyarwa, inda zaku iya gano yadda ake amfani da katako yadda yakamata, haɗa allura da allura. Kafin gudanar da insulin, dole kirinjin aƙalla ya zama aƙalla sa'o'i biyu a zafin jiki. Ba zai yiwu a sake amfani da katunan batattu ba.
Yana yiwuwa a adana insulin Lantus a ƙarƙashin yanayin zafin jiki daga digiri 2 zuwa 8 a cikin duhu, nesa da hasken rana kai tsaye. Ya kamata a sanya magungunan ta hanyar isar da yara.
Rayuwar sel ta insulin shekaru uku ne, wanda bayan haka ya kamata a watsar da mafita, ba za a iya amfani da shi don nufin sa ba.
Analogues na miyagun ƙwayoyi
Magunguna iri ɗaya tare da tasirin hypoglycemic sun haɗa da insulin Levemir, wanda ke da kwalliya sosai. Wannan magani kwatankwacin kwalliya ce ta insulin aiki na mutum.
Ana samar da kwayar ta hanyar amfani da kwayar halitta ta halittar DNA ta hanyar amfani da wani irin nau'in Saccharomyces cerevisiae. Levemir an shigar dashi cikin jikin mai ciwon sukari ne kawai a kasa. An ba da umarnin sashi da mitar allura ta hanyar likitan halartar, gwargwadon yanayin halayen mutum na haƙuri.
Lantus zaiyi magana game da insulin daki-daki a cikin bidiyo a wannan labarin.