Ciprofloxacin 250 da Allunan kwayoyi 500

Bayanin da ya dace da 20.08.2015

• Sunan Latin: Ciprofloxacinum
• Lambar ATX: S03AA07
• Aiki mai aiki: Ciprofloxacin (Ciprofloxacinum)
• Mai masana'anta: PJSC “Farmak”, PJSC “Technologist”, OJSC “Kyivmedpreparat” (Ukraine), LLC “Ozon”, OJSC “Veropharm”, OJSC “Synthesis” (Russia), C.O. Kamfanin Rompharm S.R.L. (Romania)

Kunnuwa da ido saukad da ciprofloxacin dauke ciprofloxacin hydrochloride a taro na 3 MG / ml (dangane da tsarkakakken abu), Trilon B, chloride benzalkonium, chloride sodium, tsarkakakken ruwa.

A cikin maganin shafawa na ido, shima abu mai aiki shima yana kunshe ne a cikin adadin 3 mg / ml.

Allunan Ciprofloxacin: 250, 500 ko 750 mg na ciprofloxacin, MCC, sitaci dankalin turawa, sitaci masara, hypromellose, croscarmellose sodium, talc, magnesium stearate, colloidal anhydrous silicon dioxide, macrogol 6000, ƙari E171 (titanium dioxide), polysorbate 80.

Maganin jiko ya ƙunshi abu mai aiki a taro na 2 MG / ml. Wadanda suka kware: sodium chloride, edetate disodium, lactic acid, diluted hydrochloric acidruwa d / da.

Pharmacodynamics

Hanyar aiwatar da miyagun ƙwayoyi ta kasance ne saboda ikon hana DNA gyrase (wani enzyme na ƙwayoyin ƙwayoyin cuta) tare da haɗuwa da kwayar halittar DNA, rarrabuwa da haɓakar ƙwayoyin cuta.

Wikipedia yana nuna cewa, a kan asalin amfani da miyagun ƙwayoyi, ba a haɓaka juriya ga sauran abubuwan da ba masu gicci ba, maganin rigakafi. Wannan yana sanya ciprofloxacin tasiri sosai akan kwayoyin da suke tsayayya da aiki. penicillins, wuraren kashe gobara, tetracycline, banasamil da kuma wasu da dama maganin rigakafi.

Mafi aiki akan Gram (-) da Gram (+) aerobes: H. hargitsi, N. gonorrhoeae, Salmonella spp., P. aeruginosa, N. meningitidis, E. coli, Shigella spp.

Inganci a cikin cututtukan da ke haifar da: damuwa staphylococcus (haɗe da waɗanda ke samar da penicillinase), nau'in damuwa guda ɗaya enterococcus, legionella, kampillobacter, chlamydia, mycoplasma, mycobacteria.

Aiki a kan samar da microflora na beta-lactamase.

Anaerobes suna da hankali ko magungunan juriya. Saboda haka, marasa lafiya tare da gauraye kamuwa da cuta da cututtukan ƙwayar cuta aerobic Ya kamata a ƙara amfani da maganin ciprofloxacin ta hanyar sayan magani lincosamides ko Metronidazole.

Tsayayya a maganin rigakafi sune: Ureaplasma urealyticum, furucin Streptococcus, Treponema pallidum, Nocardia asteroides.

An haifar da juriya da kwayoyin hana kwayoyi ga kwayoyi a hankali.

Pharmacokinetics

Bayan shan kwaya, ƙwayar ta hanzarta da cikakkiyar ƙwayar narkewa.

Babban alamomin magunguna:

• bioavailability - 70%,
• TCmax cikin jini jini - 1-2 awanni bayan gudanarwar,
• T½ - 4 hours

Tsakanin 20 zuwa 40% na abu ya haɗa da sunadaran plasma. Ciprofloxacin yana da kyau a rarraba shi cikin ruwa mai rai da kyallen jiki, kuma maida hankali ne a kyallen takarda da ruwa sosai na iya wuce plasma.

Yana ratsa cikin mahaifa cikin ruwa na cerebrospinal, an keɓe shi a cikin madarar nono, kuma an tsayar da babban taro cikin bile. Kusan kashi 40 cikin dari na kashi da aka dauka ana cire shi cikin sa'o'i 24 ba tare da kodan ya canza shi ba, ana cire wani ɓangaren kashi a cikin bile.

Menene maganin don ƙurawar ido / kunne saukad da?

Ana amfani da maganin ophthalmology cututtukan ƙwayar cuta na waje na ido (ido) da kayan aikinta, harda da keratitis.

Alamu don amfanin ciprofloxacin a ilmin halitta: m kwayoyin otitis externa da m kwayoyin otitis kafofin watsa labarai na tsakiyar kunne a cikin marasa lafiya tare da bututun bututu.

Contraindications

Contraindications don amfani na tsari:

• yawan tashin hankali
• ciki
• lactation
• furta koda / koda na hanta,
• alamomin tarihin tarihin rarrabuwar ƙwaƙwalwa ta hanyar amfani da quinolones.

Saukad da idanu da kunnuwa suna cikin ciki fungal da cutar hoto ko bidiyo mai zagaya yanar gizo da sauri cututtukan idanu / kunnuwa, tare da rashin haƙuri zuwa ciprofloxacin (ko wasu quinolones), yayin ciki da lactation.

Ga yara, allunan da kuma mafita don gudanar da iv za a iya tsara su daga shekaru 12, ido da kunne sun ragu daga shekara 15.

Side effects

An yarda da maganin sosai. Mafi yawan sakamako masu illa ga ciki tare da kan / a cikin gabatarwar da shigowa:

• tsananin farin ciki
• gajiya
• ciwon kai
• rawar jiki
• taimako.

A cikin littafin Vidal, an ba da rahoton cewa a cikin lokuta daban, marasa lafiya sun yi rikodin:

• gumi
• gait cuta
• na kewaye damuwa da hankali,
• tides,
• hauhawar ciki,
• bacin rai,
• jin tsoro
• karancin gani
• rashin tsoro,
• ciwon ciki
• baƙin ciki,
• tashin zuciya / amai
• zawo,
• hepatitis,
• hepatocyte necrosis,
• samarin,
• hauhawar jini(da wuya)
• fata mai ƙaiƙayi
• bayyanar rashes akan fatar.

M rare sakamako masu illa: karin ƙarfe, amafflactic rawar jiki, Harshen Quincke's edema, arthralgia, petechiae, m exudative erythema, vasculitis, Ciwon Lyell, cutar kuturta da cutar sankarar mahaifa, eosinophilia, anemia, hemolytic anemia, thrombotic ko leukocytosis, increasedarin yawan ƙwayoyin plasma na LDH, bilirubin, alkaline phosphatase, transaminases hanta, creatinine.

Aikace-aikacen ilimin aikin likita tare da:

• sau da yawa - jin rashin jin daɗi da / ko kasancewar jikin wata ƙasa a cikin ido, bayyanar fararen farar fata (yawanci a cikin marasa lafiyakeratitis kuma tare da yawan amfani da saukad da), samuwar lu'ulu'u / flakes, conjunctival overlay da hyperemia, tingling da kona,
• a cikin lokuta daban - keratitis/keratopathy, ƙyallen fatar ido, ƙarancin cornea, halayen ɗorawa, ƙarancin girman jiki, raguwar gani na gani, daukar hoto, ɓarnawar ƙasa.

Sakamakon sakamako wanda aka danganta da shi ko yiwuwar amfani da amfani da miyagun ƙwayoyi yawanci mai saukin kai ne, ba shi da wata barazana kuma yana tafi ba tare da magani ba.

A cikin marasa lafiya tare da keratitis bayyanar farin shafi ba ya cutar da cutar don magance cutar da kuma sigogin hangen nesa kuma ya bace da kanshi. A matsayinka na mai mulki, ya bayyana a cikin zamani daga kwanaki 1-7 bayan fara aiwatar da amfani da miyagun ƙwayoyi kuma ya ɓace nan da nan ko a cikin kwanaki 13 bayan dakatarwa.

Rashin lafiyar neophhalmicmic lokacin amfani da saukadwa: bayyanar wani mummunan tashin hankali a cikin bakin, a lokuta mafi wuya - tashin zuciya, dermatitis.

Lokacin da aka yi amfani da shi a cikin ilimin Halittu, waɗannan masu yiwuwa ne:

• sau da yawa - rushe a cikin kunne,
• a wasu yanayi - tinnitus, ciwon kai, dermatitis.

Amfani da ampoules

Ciprofloxacin a cikin ampoules bada shawarar da za a gudanar a cikin jijiya a cikin hanyar drip jiko. Yawan maganin manya shine 200-800 mg / day. Tsawon karatun yana kan matsakaici daga mako 1 zuwa kwana 10.

A cututtukan urogenital, hadin gwiwa lalacewadakasusuwa ko Kwayoyin ENT mai haƙuri yana yin allurar 200-400 sau biyu a rana. A cututtuka na numfashi, kamuwa da cuta cikin ciki, cutar sanƙarau, laushi mai laushi da raunukan fata kashi daya tare da iri daya na amfanin shine 400 MG.

A koda dysfunction kashi na farawa shine 200 MG, daga baya an daidaita shi cikin la'akari da Clcr.

Game da amfani da ampoules a cikin kashi 200 na MG, tsawon lokacin jiko shine minti 30, tare da gabatarwar miyagun ƙwayoyi a cikin kashi 400 MG - 1 awa.

Ba a sanya allurar Ciprofloxacin ba.

Zabi ne

Babu wani bambanci na asali game da yadda ake shan kwayoyi daga masana'antun daban-daban: umarnin don amfani Ciprofloxacin-AKOS kama da umarnin kan Ciprofloxacin-FPO, Ciprofloxacin -Anyi alkawarinshi, Vero-Ciprofloxacinko Ciprofloxacin-teva.

Ga yara da matasa da ke ƙasa da shekara 18, an ba da shawarar yin amfani da miyagun ƙwayoyi ne kawai idan ƙwayar cuta ta iya tsayayya da sauran jami'ai masu ƙwaƙwalwar ƙwayar cuta.

Yawan damuwa

Babu takamaiman bayyanar cututtuka tare da yawan abin sama da ya faru na ciprofloxacin. Ana nuna mai haƙuri da raunin ciki, shan magungunan ƙwayoyin cuta, ƙirƙirar halayen fitsari na acidic, da kuma gabatar da babban ruwa. Dukkanin ayyuka yakamata a gudanar dasu yayin riƙe aikin mahimman tsari da gabobin jiki.

Tsarin diyya da maganin hemodialysis taimaka wajan kawar da kashi 10% na maganin da aka dauka.

Magungunan ba shi da takamaiman maganin rigakafi.

Haɗa kai

Yi amfani a hade tare da Kalamunda yana ba da gudummawa ga karuwa a cikin ƙwayar plasma da haɓaka T1 / 2 na ƙarshen.

Magungunan antioxid na Al / Mg suna taimakawa rage jinkirin ciprofloxacin kuma hakan zai rage maida hankali a fitsari da jini. Tsakanin allurai na wadannan magungunan ya kamata a kiyaye jinkirin da akalla sa'o'i 4.

Ciprofloxacin yana haɓaka sakamako coumarin anticoagulants.

Ba a yi nazarin hulɗa na ciprofloxacin don amfani da shi a cikin ilimin likitanci da likitancin ophthalmology tare da wasu kwayoyi ba.

Umarni na musamman

Sakamakon yiwuwar tasirin sakamako daga tsarin juyayi na tsakiya a cikin marasa lafiya tare da tarihin tarihinta, ana iya amfani da miyagun ƙwayoyi don dalilai na kiwon lafiya kawai.

An wajabta Ciprofloxacin da taka tsantsan lokacin da ragewan ƙwancen ƙorafi don shiri mai daɗi, fargaba, lalata kwakwalwa, mai tsanani cerebrosclerosis (haɓaka da rashin yiwuwar wadataccen tsarin samar da jini da bugun jini), a mummunan rauni hanta / aikin kodacikin tsufa.

A lokacin jiyya, ana ba da shawarar don guje wa UV da hasken rana da ƙara yawan aiki na jiki, don sarrafa yawan fitsari da tsarin shan ruwa.

A cikin marasa lafiya tare da alkaline na fitsari, an yi rikodin lokuta babbar murya. Don guje wa ci gabansa, ba a yarda da shi ya wuce maganin warkewar maganin ba. Bugu da kari, mara lafiyan na bukatar shan abin sha da yawa da kuma kula da fitsari na fitsari.

Tendon zafi da alamu catarwar alama alama ce ta dakatar da jiyya, tunda ba za a daina jijiyar cutar / huda jijiya ba.

Ciprofloxacin na iya hana saurin ƙwaƙwalwar psychomotor (musamman a kan asalin giya), wanda yakamata ya tuna da marasa lafiyar da ke aiki tare da na'urorin haɗari.

Tare da ci gaba tsananin zawoya kamata a cirecututtukan mahaifasaboda wannan cutar itace contraindication zuwa amfani da miyagun ƙwayoyi.

Idan ya cancanta, tsarin iv na lokaci guda na barbiturates ya kamata ya lura da aikin CCC: musamman, ECG, raunin zuciya, hawan jini.

Rashin maganin ophthalmic na miyagun ƙwayoyi ba a nufin allurar ciki ba.