Allunan dicinon: umarnin don amfani

Dicinon yana samuwa a cikin allunan kuma a cikin nau'i na mafita don allura.

Abubuwan da ke aiki na miyagun ƙwayoyi shine ethamsylate. Mayar da hankali a cikin kwamfutar hannu guda ɗaya shine 250 MG, a cikin 1 ml na bayani - 125 MG.

A matsayin abubuwan taimako, allunan Dicinon sun hada da citric acid na anhydrous, sitaci masara, magnesium stearate, povidone K25, lactose.

Baya ga ethamylate, mafita ya ƙunshi sodium disulfite, ruwa don allura, sodium bicarbonate (a wasu lokuta ya zama dole don daidaita matakin pH).

Allunan an ba su magunguna cikin fakitoci 10 cikin roba; ana sayar da blister 10 a cikin kwali na kwali. Iya warware matsalar bugun ciki da na jijiyoyin jiki an gano shi cikin ampoules na gilashi mara launi tare da ƙara 2 ml, ampoules 10 a cikin kumburi, 5 jijiyoyi a cikin kwali.

Alamu don amfani

Amfani da Dicinon ya nuna don magani da rigakafin zubar jinni na asalin asali.

Dangane da umarnin, etamzilat yana da tasiri a cikin:

• Zubda jini da ke faruwa yayin da kuma bayan tiyata a kan duk abubuwan da ke da kyau (an lalata shi ta hanyar jijiyoyin jini) kyallen a cikin mahaifan mahaifa da likitan mata, aikin ENT, likitan hakori, tiyata na filastik, maganin cututtukan mahaifa, ophthalmology,
• Menorrhagia, gami da firamare, haka kuma a cikin matan da ke hana daukar ciki na ciki,
• Maganin zubar jini
• Hematuria,
• Hanci,
• Karin Matarwar,
• Cutar zazzabin cizon sauro na zuciya, da suka hada da hemophthalmus, cututtukan cututtukan cututtukan zuciya da sauransu,,,
• Cututtukan cututtukan cututtukan mahaifa a cikin jarirai, gami da jarirai.

Contraindications

Dangane da umarnin Dicinon, amfani da miyagun ƙwayoyi ya saba idan mai haƙuri yana da:

• Cutar cututtukan cututtukan cututtukan ƙwayar tsoka da ƙwayar tsoka da ciwan ciki, da suka haɗa da osteosarcoma, myeloblastic da cutar sankarar fata,
• Damuwa
• M porfria,
• Karafarini
• Rashin hankali ga abubuwan da ke jikin allunan / bayani.

Ana amfani da Dicinon tare da taka tsantsan don kula da marasa lafiya da tarihin cutar ƙwararru na jini ko ma'amalar ƙwayar cuta, da kuma a yanayin inda sanadin zubar jinni shine yawan maganin cututtukan anticoagulants.

Sashi da gudanarwa

Mafi kyawun maganin yau da kullun na Dicinon a cikin kwamfutar hannu ga mazan ya kasance daga 10 zuwa 20 MG da 1 kg na nauyin jiki. Raba shi cikin allurai 3 ko 4.

A matsayinka na mai mulki, matsakaicin matsakaici shine 250-500 MG, a lokuta na musamman an kara shi zuwa 750 MG. Mitar amfani da Dicinon iri daya ce, sau 3-4 a rana.

A cikin menorrhagia, kashi na etamzilate na yau da kullum shine daga 750 MG zuwa 1 g. Dicinon zai fara ɗauka daga ranar 5th na jinin haila kuma har zuwa ranar 5th na sake zagayowar gaba.

Bayan abubuwan tiyata, ana bada shawarar a sha magani a cikin kowane sa'o'i 6 a 250-500 mg. An ci gaba da shan kwayoyin cutar har sai an ci gaba da barazanar zubar jini.

Ga yaro, kashi ɗaya shine 10-15 mg a 1 kg na nauyin jiki. Yawan aikace-aikacen da yawa - sau 3-4 a rana.

Umarni don Dicinon ya nuna cewa allura an yi nufin jinkirin cikin ciki ne ko allurar cikin ciki. A cikin halayen da ke gurbata magani tare da gishirin, ya kamata a yi allura nan da nan.

Ga balagaggu, maganin yau da kullun shine 10-20 mg / kg / day, yakamata a raba shi zuwa cikin injections 3-4.

Don dalilai na prophylactic a lokacin ayyukan tiyata, ana gudanar da Dicinon iv ko IM a cikin kashi 250-500 mg kimanin sa'a daya kafin tiyata. Yayin aikin tiyata, ana gudanar da maganin a cikin jijiyoyin jiki a cikin kwatankwacin wannan, idan ya cancanta, an maimaita gabatar da wannan maganin. A cikin bayan aikin, ana bada shawarar yin amfani da Dicinon a farkon farawa kowane awa 6 har sai hadarin zubar jini ya shuɗe.

Ga yara, an sanya maganin a cikin kashi na 10-15 mg / kg / rana, an raba shi zuwa injections 3-4. A cikin aikin neonatological, Dicinon an allura shi a cikin tsoka ko a hankali a cikin jijiya a kashi na 12.5 mg / kg (ƙayyadadden kashi na ethamylate ya dace da 0.1 ml na mafita). Jiyya yana farawa a cikin sa'o'i biyu na farko na rayuwar yaro.

Umarni na musamman

Maganin allurar dicinon an yi shi kawai don amfani a asibitoci da asibitoci.

Haramun ne a haxa maganin a cikin sirinji guda tare da kowane magani. An contraindicated don amfani da mafita idan ya canza launi.

Ya kamata a ɗauka a cikin zuciya cewa Dicinon a cikin kashi 10 mg / kg, ana sarrafa shi awa ɗaya kafin ma'anar 'yan jujjuyawar, yana hana tasirin maganin su. Kuma Dicinon, wanda aka gabatar bayan dextrans, ba shi da tasirin hemostatic.

Dicinone bai dace da maganin sodium lactate da sodium bicarbonate don maganin allura ba. Idan ya cancanta, ana iya haɗe shi da sodium menadione bisulfite da aminocaproic acid.

Tabletaya daga cikin kwamfutar hannu na Dicinon ya ƙunshi 60.5 mg na lactose (matsakaicin adadin da aka yarda da wannan abun shine gram 5). Allunan suna cikin ƙwayoyin cuta a cikin marasa lafiya da rashi lactase, rashin haƙuri na glucose, ƙwaƙwalwar ƙwayar glucose da galactose.

Kodayake Dicinon an yi niyya ne don gudanarwa na ciki da jijiyoyin jini, ana iya amfani da shi azaman, misali, bayan hakora haƙora ko gaban wani rauni. A saboda wannan, wani ɗan ɗamarar gauze ko bakararre swab an yalwata da yawa tare da mafita kuma ana amfani da lalacewa.

Sharuɗɗan da yanayin ajiya

Dicinon yana cikin rukunin magungunan da aka sayar da takardar sayan magani.

Dangane da umarnin, yakamata a adana magungunan a wani wuri mai kariya daga haske da danshi (don allunan), daga isar yara, inda za'a kiyaye yawan zafin jiki baya wuce 25 ºС. Rayuwar shiryayye na ampoules da allunan shine shekaru 5.

An sami kuskure a cikin rubutun? Zaɓi shi kuma latsa Ctrl + Shigar.

Aikin magunguna

Aikin Dicinon mai aiki shine ethamylate.

Magungunan yana da tasirin hemostatic (yana dakatarwa ko rage zubar jini), wanda ya faru ne saboda damar da miyagun ƙwayoyi ta kunna samuwar thromboplastin lokacin da ƙananan jiragen ruwa suka lalace (waɗanda aka kafa a farkon matakan aikin coagulation).

Amfani da Dicinon na iya haɓaka samuwar mucopolysaccharides (kare ƙwayoyin furotin daga rauni) na babban taro a cikin ganuwar capillaries, daidaita yanayin ikon capillaries, ƙara kwanciyar hankali, inganta microcirculation.

Dicinon bashi da ikon haɓaka coagulability na jini kuma yana haifar da vasoconstriction, kuma baya bayar da gudummawa ga samuwar ƙarar jini. Dicinon ya fara aiki 1-2 awanni bayan maganin baka da mintuna 5-15 bayan allura. Ana lura da tasirin dicinone cikin awa 4-6.

Pharmacokinetics

Lokacin gudanar da shi, etamsylate yana dafe cikin hanji daga hanji. Bayan gudanar da maganin bakin ciki na 50 mg na ethamsylate, matsakaicin matakin plasma (kimanin 15 μg / ml) ya isa bayan sa'o'i 4. Filayen rabin-plasma shine tsawon awa 3.7. Kusan kashi 72% na kashin da aka ɗauka an fesa shi a cikin fitsari a cikin awanni 24 na farko.

Ethamsylate ya haye shingen mahaifa kuma ya shiga cikin nono.

Haihuwa da lactation

Ba a san sakamakon etamzilate a kan mata masu juna biyu ba. Ethamsylate ya ratsa allurar cikin mahaifa, don haka yin amfani da shi ya kewaya ne a farkon farkon haihuwa. Amfani da asibiti yayin daukar ciki ba ya da mahimmanci ga waɗannan alamun.

Ethamsylate ya shiga cikin nono. Bai kamata ku shayar da nono yayin shan wannan magani ba.

Sashi da gudanarwa

Yi amfani da a cikin manya da yara fiye da shekaru 14

Kafin aikin tiyata: Allunan guda biyu na Dicinon 250 MG (250-500 mg) na sa'a daya kafin a yi aikin tiyata.

Bayan tiyata: daya a cikin allunan guda biyu na Dicinon 250 MG (250-500 mg) kowane awa 4-6, yayin da akwai haɗarin zubar jini.

Cututtukan ciki: shawarwarin gaba ɗaya don ɗaukar alluna biyu na 250 MG biyu Dicinon sau uku a rana (1000-1500 mg) tare da abinci tare da karamin adadin ruwa. Gynecology, don meno- / metroragia: ɗauki Allunan guda biyu na Dicinon 250 MG sau uku a rana (1.500 MG) yayin cin abinci tare da karamin adadin ruwa. Jiyya yana ɗaukar kwanaki 10, yana fara kwana biyar kafin farkon zubar jinni.

A cikin ilimin yara (yara kanana shekaru 6)

Girman yau da kullun shine 10-15 mg / kg na nauyin jiki kowace rana, an raba shi zuwa kashi 3-4. Tsawon lokacin amfani da miyagun ƙwayoyi ya dogara da yawaitar zubar jini kuma yana ɗaukar kwanaki 3 zuwa 14 daga lokacin dakatar da zub da jini a cikin duk ɓangarorin marasa lafiya.

Ya kamata a ɗauki allunan lokacin abinci ko bayan abinci .. Yawan Jama'a na Musamman

Babu karatuttukan a cikin marasa lafiya da ke fama da hanta ko ƙwayar koda. Don haka, wajibi ne don amfani Dicinon tare da taka tsantsan a cikin waɗannan rukunin masu haƙuri

Kada ku ɗauki kashi biyu don rama abin da aka rasa.

Side sakamako

Matsalar da ba a iya amfani da ita: ciwon kai, dizziness, facial flushing, rikicewar fata na yau da kullun, tashin zuciya, ciwon ciki, jijiyoyin kafa, paresthesia. Wadannan halayen na lokaci ne da laushi.

Akwai shaidu cewa a cikin yara masu fama da cututtukan ƙwayar cutar hanji da na myelogenous leukemia, osteosarcoma, etamsylate, an wajabta don rigakafin zub da jini, ya haifar da mummunar cutar leukopenia. Dangane da yawancin bayanan da aka buga, amfani da etamzilate a cikin yara ya saba wa aiki.

Akwai tabbaci cewa matan da suka dauki ethamsilate kafin tiyata sun mallaki thrombosis bayan tiyata a cikin mahaifa. Koyaya, gwaje-gwaje na kwanan nan ba su tabbatar da waɗannan bayanan ba.

Siffofin aikace-aikace

Dole ne a tsara wannan magani tare da taka tsantsan idan akwai tarihin thrombosis ko thromboembolism a cikin marasa lafiya, ko kuma rashin hankali ga magunguna. Dicinon ya ƙunshi sulfites, wanda shine dalilin da ya sa dole ne a kula da shi yayin gudanar da shi ga marasa lafiya da asma da rashin lafiyar jiki. Kafin fara magani, dole ne a haɗu da shi cewa ƙwayar ba ta da amfani a cikin marasa lafiya tare da thrombocytopenia.

Saboda gaskiyar cewa a cikin yara da aka wajabta wa Dicinon don hana zubar jini a cikin lymphoblastic da myeloid leukemia da osteosarcoma, yanayin ya tsananta, wasu marubutan sunyi la'akari da amfani da miyagun ƙwayoyi a cikin waɗannan halayen don contraindicated.

Bai kamata a sanya magunguna ga masu haƙuri da irin waɗannan cututtukan da ke tattare da cututtukan gado kamar ƙarancin lactase ko malabsorption na glucose-galactose.

Ethamsylate ba ya tasiri da ikon fitar da motoci da aiki tare da kayan aiki.

Idan baka yarda da carbohydrates, nemi likita kafin ka sha magani.

Magunguna da magunguna

Magungunan yana ƙarfafa tsarin fita daga platelet daga kashin kashiyana karfafa iliminsu. Magungunan suna da antiplatelet da tasirin angioprotective. Magungunan yana taimakawa dakatar da zubar jini, yana kara yawan samuwar na farko thrombusEthamylate yana haɓaka tserewa, baya tasiri lokacin prothrombinfibrinogen taro. Tare da sake yin amfani da miyagun ƙwayoyi, thrombosis yana ƙaruwa. Dicinon yana rage diapedesis na sifar, abubuwa na jini daga gado na jijiyoyin jiki, yana rage fitowar ruwa, yana tasiri sosai microcirculation. Magungunan ba ya shafar sigogi na al'ada da sigogi na tsarin hemostatic. Dicinon yana da ikon mayar da lokaci mai canza yanayin jini a cikin cututtuka daban-daban.

Ana jin tasirin sakamako mai zurfi bayan minti 10-15. Matsakaicin matakin mafi girman abu mai aiki ya kai sa'a daya bayan gudanarwa. An cire ta ba'a canzawa ba a farkon rana kusan tare da fitsari.

Umarnin don amfani da Dicinon

Dicinone yana samuwa ta hanyar samar da mafita don allurar ciki da allura da kuma a cikin nau'ikan allunan da aka yi niyya don sarrafa bakin. Aikace-aikacen gida na gida na Dicinone shima ana iya yiwuwa ta hanyar amfani da swab a cikin mafita don raunin. Ampoule daya da kwamfutar hannu guda ɗaya kowannensu suna da 250 mg na etamsylate.

A mafi yawancin lokuta, ana bada shawarar a ɗauki allunan Dicinon a cikin adadin kwamfutar 1-2. a lokaci, idan ya cancanta, ana iya ƙara kashi zuwa 3 inji mai kwakwalwa. Aari ɗaya na maganin don allura yawanci yayi daidai da ½ 1 ampoule, in ya cancanta - 1 po ampoule.

Don dalilai na prophylactic kafin tiyata: 250-500 MG na etamsylate ta allurar ciki ko allura ta 1 awa kafin tiyata ko allunan 2-3 na Dicinon 3 hours kafin tiyata. Idan ya cancanta, gudanar da jijiyoyin jini na 1-2 ampoules na miyagun ƙwayoyi yayin tiyata mai yiwuwa ne.

Zubin jini na ciki da na huhu suna ba da shawarar shan Allunan guda biyu na Dicinon kowace rana tsawon kwanaki 5-10, idan har akwai buƙatar tsawaita aikin magani, ana rage kashi na maganin.

Dicinon don haila yana da shawarar shan allunan 3-4 a kowace rana don kwanaki 10 - fara 5 kwanaki kafin haila kuma ƙare ranar 5 na haila. Don ƙarfafa tasirin, ya kamata a ɗaukar allunan Dicinon gwargwadon tsarin da hanyoyin haɓaka biyu masu zuwa.

A cikin kwanaki 5-14, ana bada shawara don ɗaukar allunan 3-4 na Dicinon don cututtukan tsarin jini, dipathesis na jini da cututtukan cututtukan zuciya (lalacewar tasoshin jini).

Kafin ayyukan don dalilai na prophylactic, an sanya wa yara Dicinon a 1-12 mg / kg kowace rana don kwanaki 3-5. Yayin aikin, gudanarwar cikin ciki na 8-10 mg / kg mai yiwuwa ne, kuma bayan tiyata don hana zub da jini - 8 MG / kg a cikin nau'ikan allunan Dicinon.

Ana maganin cututtukan hemorrhagic a cikin yara ta hanyar sarrafawa na baka na 6-8 mg / kg sau 3 a rana don kwanaki 5-14.

A cikin microgoniopathy na ciwon sukari, ana shawarar Dicinon da za a gudanar da shi ta intramuscularly a kashi na 125 mg, sau 2 a rana don watanni 2-3.

Side effects

Dicinon, amfanin wanda yakamata a yarda dashi tare da likita, na iya haifar da sakamako wanda ba a so kamar su nauyi a cikin jijiyoyin ciki (ɓangaren ɓangaren bango na ciki), ƙwannafi, zubar da jini a fuska, tsananin farin ciki, ciwon kai, ƙoshin ƙafafu, raguwar hauhawar jini, halayen rashin lafiyan.

Haɗa kai

Kada a haɗa Dicinon da wasu magunguna a cikin sirinji iri ɗaya. Don hana aikin antiplatelet tsautsayi Ana sarrafa dicinone awa daya kafin amfani dasu a kashi 10 mg / kg. Yin amfani da etamzilate bayan wannan lokacin ba ya ba da sakamako mai illa. Za'a iya haɗu da maganin tare da menadione sodium bisulfite, aminocaproic acid.

Form sashi

Allunan kwayoyi 250 MG

Tabletaya daga cikin kwamfutar hannu ya ƙunshi:

abu mai aiki - etamsylate 250 MG

magabata: citrus acid na nitsewa, sitaci masara, lactose monohydrate, povidone, magnesium stearate.

Allunan suna zagaye cikin tsari, tare da saman biconvex, daga fari zuwa kusan fararen fata.

Kayan magunguna

PharmacokineticsDamuwa Bayan gudanar da baki, ana shayar da maganin a hankali daga hanji. Bayan shan magani a cikin kashi 500 MG, mafi girman taro a cikin jini yana zuwa bayan awa 4 kuma shine 15 μg / ml.

Matsakaicin ɗaukar nauyin sunadaran plasma kusan 95%. Ethamsylate ya tsallake katangar mahaifa. Jinin mahaifa da na cikin igiyar sel suna da kamala na etamsylate. Babu bayanai game da rarraba ethamsylate tare da madara.

Kiwo Etamsylate an cire ta da kodan ba canzawa. Rabin rayuwar daga jini (jini) shine kimanin awa 8. Kimanin kashi 70-80% na kashin da aka dauka an cire shi ne a cikin awowi 24 na farko da fitsari bai canza ba.

Pharmacokinetics a cikin marasa lafiya da ke fama da hanta da ƙwayar koda

Abubuwan da ke cikin pharmacokinetic na etamsylate a cikin marasa lafiya da ke fama da raunin hanta da koda koda ba a yi nazari ba.

Pharmacodynamics Ethamsylate magani ne mai haɓaka hemostatic da angioprotective magani wanda aka yi amfani dashi azaman wakilin farko na hemostatic (hulɗa da endothelium-platelets). Ta hanyar inganta adheshin platelet da dawo da juriya, maganin yana samar da raguwa sosai a lokacin zubar jini da raguwa cikin zubar jini.

Ethamsylate ba shi da tasirin vasoconstrictor, ba ya shafar fibrinolysis, kuma baya canza abubuwan coagulation na plasma.

Yi amfani da lokacin daukar ciki da lokacin shayarwa

Babu wani bayanan asibiti game da yiwuwar amfani da Dicinon a cikin mata masu juna biyu. Amfani da Dicinon yayin daukar ciki zai iya yiwuwa ne kawai idan amfanin da aka yi niyya ga mahaifiya ya fi gaban hadarin da tayi.
Babu bayanai game da rarraba ethamsylate tare da madara.
Saboda haka, lokacin amfani da miyagun ƙwayoyi yayin shayarwa, ya kamata a yanke shawarar batun dakatar da shayarwa.

Yawan damuwa

Har zuwa yau, babu batun adadin yawan haɗarin da aka ambata.
Idan yawan abin sama da ya kamata ya faru, to yakamata a fara gwajin cututtukan kwakwalwa.

Yin hulɗa tare da wasu kwayoyi

Har yanzu babu bayanai game da hulɗar etamsylate tare da wasu kwayoyi.
Wataƙila haɗuwa tare da aminocaproic acid da kuma sodium menadione bisulfite.