Yadda za a yi amfani da miyagun ƙwayoyi Biosulin?

Magungunan suna da siffofin sashi uku:

• Maganin allurar Biosulin P,
• Dakatar da harkar sc of Biosulin N,
• Dakatarwa ga sc gwamnati ta Biosulin 30/70.

Ilaya daga cikin milliliter na allura ya ƙunshi IU 100 na inulin da aka ƙera shi, da kuma abubuwan taimako kamar ruwa don allura, metacresol da glycerol.

Ilaya daga cikin milliliter na dakatarwar Biosulin N ya ƙunshi IU 100 na abubuwa masu aiki da kuma ƙarin ƙarin waɗannan: zinc oxide, sodium hydrogen phosphate, sulfate protamine, crystalline phenol, metacresol, glycerol, allurar ruwa.

Ilaya daga cikin mililiter na 30/70 dakatarwar ya ƙunshi cakuda insulins na durations daban-daban na aiki (gajeru da matsakaici): insulin ɗan adam mai narkewa da isofaninsulin ɗan adam a cikin rabo na 30:70.

Saki siffofin da abun da ke ciki

Biosulin P tare da saurin fara ayyukansa an yi shi ne ta hanyar mafita don injections. 1 cm³ ya ƙunshi 100 IU ml na insulin da aka samar ta amfani da fasahar injiniya. Bugu da ƙari, abun da ke cikin maganin ya haɗa da glycerin, metacresol da ruwa na musamman don allura. Ampoules suna cikin fakitin launuka iri-iri.

Biosulin H matakin tsaka-tsakin yanayi an yi shi ne ta hanyar dakatarwa don injections a karkashin fata. Fari ne, adon ɗan adana lokacin ajiya. Ana samun sauƙin dawowa yayin motsi mai girgizawa.

Aikin magunguna

Tsarin hormone yana aiki tare da masu karɓar insulin na sel, wanda a sakamakonsa ake samun gyaran glucose na jini. Ana aiwatar da tsarin yadda yake ɗaukar ƙwayar cuta da ƙwayar tsoka, ƙirar glycogen tana aiki, kuma an rage yawan haɓakar glucose a cikin ƙwayoyin hanta.

Bioaddamar da ayyukan Biosulin masu matsakaici-matsakaici daga 1 zuwa 2 hours. Babban tasiri yana faruwa bayan sa'o'i 6-12, kuma jimlar aikin yana zuwa 24 hours.

Tsarin hormone yana aiki tare da masu karɓar insulin na sel, wanda a sakamakonsa ake samun gyaran glucose na jini.

Yunkurin aiwatar da aikin hypoglycemic na biosulin gajere shine kusan minti 30. Babban sakamako bayan an lura da allura a cikin kewayon awa 2-4, matsakaita tsawon lokacin aikin shine awoyi 6-8.

Alamu don amfani

Biosulin H an nuna shi don amfani dashi a cikin bincike game da cutar sukari irin ta 1. A nau'in 2, an wajabta su ga marasa lafiya saboda tsayayya da su game da rage ƙwayoyi na rage sukari.

Biosulin H an nuna shi don amfani dashi a cikin bincike game da cutar sukari irin ta 1.

Tare da ciwon sukari

An ƙaddara yawan maganin yau da kullun gwargwadon halayen mai haƙuri. Wajibi ne a lissafta adadin insulin don nauyin jiki. Matsakaicin sashi na maganin a kowace rana yana daga 0.5 zuwa 1 IU, gwargwadon nauyin jikin mutum. Insulin da aka shirya don gudanarwa ya kamata ya kasance a zazzabi a ɗakin. Mafi yawan lokuta, ana yin shi sau 3 a rana, kuma wani lokacin sau biyu. Idan adadin yau da kullun ya fi 0.6 IU / kg, to, kuna buƙatar yin allura 2 a kowane ɓangaren jiki.

An ƙaddara yawan maganin yau da kullun gwargwadon halayen mai haƙuri.

Biosulin yana allura s / c a cikin ciki, cinya, buttock, tsoka mai ƙwanƙwasa - duk inda akwai wadataccen mai mai ƙoshin mai. An canza wuraren allurar don hana ci gaban aikin lipodystrophy.

Intramuscularly ana gudanar dashi kawai a karkashin kulawa ta kwararru. Wasu lokuta ana haɗa shi da insulin matsakaici na sunan guda. Irin wannan gabatarwar yana buƙatar saka idanu akai-akai game da matakin glycemia.

Hanyar da za a gudanar da sinadarin Biosulin ta bambanta da irin maganin da aka yi amfani da shi. Lokacin amfani da insulin guda daya kaɗai, jerin ayyukan sune kamar haka:

1. Karfin ƙwayar membrane akan kwalban tare da ethanol an gudana.
2. Introduaddamar da iska a cikin sirinji a cikin adadin daidai yake da adadin da aka wajabta, sannan cika kwalban da adadin adadin iska.
3. Juya shi 180º ƙasa kuma buga lambar da aka lissafta a baya na Biosulin.
4. Cire allura, cire iska daga sirinji. Tabbatar kiran bugun yayi daidai.
5. Yi allura.

Lokacin amfani da nau'ikan magani guda 2, ayyukan mai haƙuri zai zama kamar haka:

1. Kwayar cuta ta membranes dake jikin kwalabe ana yin ta.
2. Kuna buƙatar motsa kwalban tare da dogon insulin har sai maganin yana da launi daidai (ba fari).
3. Zana iska a cikin sirinji gwargwadon yawan matsakaici ko tsayi insulin. An saka allura a cikin akwati tare da insulin, saki iska kuma cire fitar da allura. A wannan lokacin, insulin matsakaici ko tsayi ba ya shiga cikin sirinji.
4. Jawo iska zuwa cikin sirinji a cikin adadi wanda zai yi ɗan gajeren insulin. Saki iska a cikin wannan kwalbar. Juya shi kuma zana a cikin adadin maganin.
5. Cire allurar, cire iska mai wuce haddi. Bincika daidai maganin.
6. Maimaita matakai iri ɗaya, tattara insulin na matsakaita ko tsayi insulin daga murfin. Cire iska.
7. Yi allura daga gaurayar insulin.

Bayan allurar, bar allura a karkashin fata na tsawon awanni 6.

Za'a iya samar da kayan aiki a cikin wani katako wanda yake da ɗigon sirinji tare da allura, 5 ml. Wani alkalami mai narkewa ya sanya 3 ml na insulin. Kafin amfani dashi, tabbatar cewa yana da matsala daga lahani. Bayan an shigar da katun a cikin sirinji, tsararren tsiri ya kamata a bayyane ta taga mai riƙe ta.

Bayan allurar, bar allura a karkashin fata na tsawon awanni 6. Duk wannan lokacin ana kiyaye maballin a cikin wurin da aka kunna, don haka an tabbatar da daidaituwa na kashi. Bayan wannan lokaci, za'a iya cire makama a hankali. Ba a yin amfani da kicin don fansa ba, an yi shi ne kawai don amfanin mutum.

Bayan ƙarshen insulin, ya kamata a watsar da shi.

Daga gefen metabolism

Zai iya haifar da rikicewar hypoglycemic. Mutum na iya fuskantar waɗannan alamun:

• pallor na fata da na mucous membranes,
• ƙara yin gumi
• palpitations
• tsoka
• da kaifi ji yunwa,
• kaifi mai annashuwa, wani lokacin tashin hankali, fushi, incoherence da rikice-rikice na tunani,
• zazzabi
• kaifi zafi a kai yankin,
• take hakkin jijiyoyin wuya.

Daga shan Biosulin, ana iya ƙara yawan zagi.
Daga shan Biosulin, ana iya samun jin zafin bugun zuciya.
Daga shan Biosulin za'a iya samun ciwo mai kaifi a yankin kai.

Tsawon yanayin kariya daga ciki na iya haifar da cutar rashin wadatar jini:

• pallor da danshi na fata,
• ya fadi karuwa a zuciya,
• danshi
• karuwa cikin sautin tsoka,
• m da m numfashi.

A cikin rashin lafiyar, mai haƙuri bai san komai ba. Ba shi da shakatawa, sautin tsoka yana raguwa, gumi yana tsayawa, bugun zuciyarsa ya tashi. Zai yiwu gazawar numfashi. Mafi haɗarin rikicewar cutar hypoglycemic coma shine ƙwaƙwalwar hanji, wanda ke haifar da kamawa na numfashi.

Tare da haɓaka waɗannan alamun, yana da mahimmanci don ba wa mutum mahimmancin kulawar likita a cikin lokaci. Da zaran an samar dashi, da kyar mutum zai ci gaba da yin cutar sihiri ta hanyar haɓaka. Gudanar da insulin a cikin yanayin rage jini glucose yana da mummunan sakamako ga masu ciwon sukari.

Tsawan jini wanda ba a kiyaye shi na wani lokaci na iya haifar da cutar hauhawar jini.

Tare da hanyar allurar Biosulin far, maganin rashin lafiyan mai yiwuwa ne: fatar fata, ƙoshin fata, matuƙar wuya - halayen anaphylactoid. Reactionwayar cikin gida a cikin allura na iya haɓaka - itching, redness, da kadan kumburi.

Umarni na musamman

Haramun ne a yi amfani da maganin lokacin da ya canza launi ko barbashi mai kauri sun bayyana a ciki. Yayin aikin jiyya, kuna buƙatar bincika adadin glucose a cikin jini. Abubuwan da ke haifar da bayyanar cututtukan cututtukan jini sune:

• maye gurbin insulin,
• yunwar tilastawa
• sharpara yawan aikin jiki,
• cututtukan da ke rage buƙatar insulin (alal misali, koda da dysfunction hanta, rage aiki adrenal, rashin aiki thyroid ko glandar ciki),
• canjin wurin allura,
• hulɗa tare da wasu magunguna.

Ofaya daga cikin abubuwan da ke haifar da bayyanar cututtukan hypoglycemia shine karuwa sosai a cikin aikin jiki.Ofayan abubuwan da ke haifar da bayyanar cututtukan cututtukan jini shine cuɗanya da wasu kwayoyi.Ofaya daga cikin abubuwan da ke haifar da bayyanar cututtukan jini yana tilasta matsananciyar yunwa.

Hutu a cikin injections na biosulin a cikin marasa lafiya da ke fama da ciwon sukari da ke dogaro da kai yana haifar da ci gaban haɓaka. Bayyananun Sa:

• bushe bakin
• urination akai-akai
• tashin zuciya da amai,
• jan fata da fata na hanji,
• rage cin abinci
• warin acetone da soyayyen apples a cikin iska mai iska.

Hyperglycemia a cikin wannan nau'in ciwon sukari ba tare da ingantaccen magani ba na iya haifar da ketoacidosis.

Canji a cikin kashi na Biosulin ana aiwatar dashi tare da:

• karuwa a cikin tsananin tsananin,
• cututtuka
• Cutar Addison
• rikicewar na pituitary gland shine yake,
• rikicewar hanta
• canjin abinci.

Canji a cikin kashi na Biosulin ana aiwatar dashi tare da cututtukan cututtuka.
Ana aiwatar da canji a cikin kashi na Biosulin tare da canjin abinci.
Ana aiwatar da canji a cikin adadin Biosulin tare da karuwa a cikin yawan nauyin.

An hana shi yin insulin na matsakaici na dogon lokaci a cikin dakatarwa idan, sakamakon girgizawa, yana karawa kuma yana da farin jini. Irin wannan hormone mai guba ne kuma yana iya haifar da guba mai tsanani. Ba a amfani da magani a cikin magungunan insulin.

Yawan adadin kwayoyin halitta na Biosulin

Idan kashi ya wuce, hypoglycemia na iya faruwa. Rashin daidaitaccen glucose ana cire shi ta hanyar cin sukari ko abinci mai dauke da carbohydrate. Mutanen da ke da ciwon sukari suna buƙatar samun kowane Sweets ko abinci tare da carbohydrates mai sauƙin narkewa tare da su koyaushe.

Ana buƙatar daidaita sashi a cikin mutane sama da 65 shekara.

Tare da coma, Dextrose an saka shi cikin jijiya, glucagon s / c, cikin jijiya ko tsoka. Da zaran hankalin mai haƙuri ya murmure, yana buƙatar cin abinci masu wadataccen sukari.

Yin hulɗa tare da wasu kwayoyi

Akwai magunguna waɗanda ke shafar buƙatar masu ciwon sukari na insulin. Tasirin rage karfin sukari da maganin yayi:

• magungunan rage sukari da aka yi amfani da shi don maganin ciwon sukari a ciki,
• MAO hana hana kwayoyi
• ckers-masu hanawa
• ACE masu hanawa
• sulfonamides,
• steroids da anabolics,
• carbonic anhydrase aiki inhibitors,
• Bromocriptine
• Pyridoxine
• Octreotide
• Ketoconazole,
• Mebendazole,
• Kalamunda
• Lantarki
• jami'ai dauke da mahallin lithium,
• duk magunguna dauke da barasa na ethyl.

Sakamakon rage ƙwayar sukari na ƙwayar ƙwayar cuta yana haifar da bromocriptine.
Sakamakon rage karfin sukari na magunguna yana haifar da Octreotide.
Sakamakon rage karfin sukari na ƙwayar ƙwayar cuta ta pyridoxine.

Wadannan mahadi suna rage ayyukan hypoglycemic na Biosulin:

• magungunan hana haihuwa na ciki
• GKS,
• cututtukan thyroid
• diuretics na jerin thiazide,
• Heparin
• wasu maganin cututtukan fata
• wakilai masu juyayi
• Clonidine hydrochloride,
• yana nufin cewa toshe aikin kalilan na alli,
• Morphine
• Phenytoin.

Shan sigari na taimaka wajan rage tasirin cutar ta Biosulin.

Amfani da barasa

Yana rage ƙarfin juriya ga ethanol.

Analogs na nau'in insulin da ake la'akari dasu sune:

• Bari mu yaudara,
• Gensulin
• Isulin insulin
• Insuran
• Alurar insulin
• Protafan
• Rinsulin
• Rosinsulin,
• Humulin
• Humulin-NPX.

Protamine-insulin shine ɗayan analogues na Biosulin.
Rinsulin yana ɗayan analogues na Biosulin.
Rosinsulin yana ɗayan analogues na Biosulin.

Nunawa game da biosulin

Irina, mai shekara 40, endocrinologist, Samara: “Don gyaran sukari na jini, na tsara madaidaici da matsakaitan bambance-bambancen kwayoyin na Biosulin ga marasa lafiya. An yarda da maganin sosai idan aka kirga sashi da lokacin gudanarwa yadda yakamata, ba a bayyanar da illa mara kyau ba. kwanaki, wanda ke nuna kyakkyawan rama ga masu cutar siga. "

Svetlana, mai shekara 38, endocrinologist, Rostov-on-Don: "Wani nau'in insulin don maganin marasa lafiya da ke da nau'in insulin-wanda ya dogara da ciwon sukari. A saboda wannan, an tsara wani tsari mai sauri na miyagun ƙwayoyi, saboda yana da mahimmanci don rama don tsalle-tsalle a cikin glucose kafin cin abinci. Yana taimaka wajan sarrafa sukari yadda yakamata a duk rana. "

Koyarwar Biosulin N Yadda za a zabi insulin aiki tsawon lokaci?

Sergey, dan shekara 45, Moscow: "Na dauki Biosulin P a matsayin daya daga cikin bambance-bambancen insulin .. Yana faruwa ne a cikin rabin awa, wato, ana iya danganta magunguna zuwa kowane abinci. A koyaushe nakan kirga yawan insulin dangane da nauyi na. da kuma yawan abinci, saboda haka cututtukan cututtukan cututtukan jini suna da wuya. Babu wasu sakamako masu illa. "

Irina, 38 shekara, St. Petersburg: "Na dauki Biosulin H a matsayin ɗayan bambance-bambancen insulin na matsakaici. Na fi so in yi amfani da sirinji na musamman: yana da aminci kuma mafi aminci. Koyaushe ina yin lissafin yawan maganin kuma in yi allura da umarnin da aka haɗa. , cututtukan cututtukan jini a wani lokaci na faruwa. Na koyi gane shi da tsayar da shi cikin lokaci. "

Masu ciwon sukari

Igor, dan shekara 50, Ivanovo: “Domin kula da ciwon sukari Ina amfani da Biosulin na matsakaici da gajeriyar magana. Idan ya cancanta, Ina gudanar da shi a cikin sirinji daya .. Magunguna da sauri yana aiki kuma baya haifar da raguwar sukari, idan babu wani nauyi ko matsi mai yawa kafin Ina cikin abinci tare da allurar insulin. Duk wannan yana sanya matakan sukari na al'ada. "

Sashi da gudanarwa

Biosulin P an yi shi ne don SC, IM da IV. Lissafin kashi da hanyar gudanar da miyagun ƙwayoyi an ƙaddara su ne kan alamu na nuna yawan glucose a cikin jini da kuma halayen mutum na mai haƙuri.

Dangane da umarnin, matsakaita na yau da kullun ya bambanta daga 0.5 zuwa 0.1 IU a kilo kilogram na nauyin jikin mai haƙuri.

Ana ba da shawarar magancewa ko dakatarwa sau uku a rana rabin sa'a kafin cin abinci ko abun ciye-ciye tare da amfani da samfuran carbohydrate. A cikin yanayin inda wannan ya zama dole, ana kara yawan hanyoyin zuwa 5 ko 6. Idan kashi na yau da kullun ya wuce 0.6 IU, ana gudanar da maganin tare da akalla allura biyu a sassa daban-daban na jiki.

A matsayinka na mai mulkin, an tsara Biosulin a cikin hanyar magance shi don sanya farashi a ƙarƙashin fata bangon ciki na ciki. An bada shawarar dakatarwa a cinya.

Don hana haɓakar lipodystrophy (ƙiba mai narkewa), ya wajaba don sauya wurin allurar a cikin yankin da aka ba da shawarar cutar ta jiki. An ba da izinin allurar cikin bango na ciki, yanki na ƙarar da ƙyallen kafada, cinya ko gindi.

Kafin amfani dashi, yakamata a sanyaya ruwan zafin jiki zuwa zazzabi daki. Zai fi kyau a yi allura a cikin fata, saboda wannan yana rage haɗarin miyagun ƙwayoyi shiga cikin tsoka.

Tun da mafita Biosulin P shine insulin gajere, ana yawan amfani dashi a hade tare da shiri na matsakaici (dakatar da Biosulin H ko 30/70).

A / m kuma a / cikin gabatarwar miyagun ƙwayoyi a cikin hanyar maganin allurar an yarda da shi kawai a ƙarƙashin kulawar likita.

Idan ya cancanta, ana iya amfani da babbar kulawa ta Biosulin N sau ɗaya ko sau biyu a rana kamar yadda basal (tushen) insulin. A matsayinka na mai mulkin, ana gudanar dashi azaman wakilin monotherapeutic da safe da maraice, kafin abincin rana ana bada shawarar yin allurar dakatarwa hade da insulin gajere.

Side effects

Ta hanyar tasiri metabolism na carbohydrates a cikin jiki, Biosulin na iya haifar da ci gaban yanayi na hypoglycemic, wanda fatar jiki ta bayyana, ƙara yawan shaye-shaye, yunwar, sanyin jiki, ciwon kai, paresthesia (tingling, numbness da rarrafe) a cikin bakin.

Idan akwai haɗari mai ƙarfi na hypoglycemia, mai haƙuri na iya faɗuwa cikin cutar rashin lafiyar hypoglycemic.

Sauran sakamakon sakamako na Biosulin da aka nuna a cikin umarnin su ne rashin lafiyan (fatar fata, kumburin Quincke, da wuya anaphylactic shock) da na gida (hyperemia, itching, soreness a wurin allura) halayen. Yin amfani da maganin na dogon lokaci na iya haifar da haɓakar lipodystrophy.

Hakanan akwai tabbacin bayyanar edema da kurakurai na ragi, waɗanda galibi ana lura da su a farkon matakan jiyya tare da Biosulin.

Sharuɗɗan da yanayin ajiya

Ya kamata a adana miyagun ƙwayoyi a cikin wani wuri mai duhu m ga yara a zazzabi na 2 zuwa 8 ºС. Kar a daskare!

Rayuwar shelf shine watanni 24. Bayan buɗe kwalbar, dole ne a yi amfani da abubuwan da ke cikin ta a cikin makonni 6. Ana ajiye kwalban buɗewa a zazzabi na 15 zuwa 25 ºС.

An sami kuskure a cikin rubutun? Zaɓi shi kuma latsa Ctrl + Shigar.