Shafin yana bada bayanin tunani don dalilai na bayanai kawai. Ya kamata a gudanar da bincike da lura da cututtuka a ƙarƙashin kulawar kwararrun. Duk magunguna suna da contraindications. Bukatar ƙwararrun masani!

Wanne magani ne mafi kyawun taimaka wa zazzabi - paracetamol ko asfirin?

Duk magungunan - duka paracetamol da asfirin suna da sakamako mai kyau na antipyretic. Koyaya, ban da rage ƙarfin zazzabi, waɗannan kwayoyi suna da kaddarorin daban-daban, wanda dole ne a la'akari da shi don fahimtar wane magani a wannan yanayin da zai fi dacewa don rage zafin jiki.

Daidai magana, ya kamata a ambaci kadarorin paracetamol da asfirin cewa ba iri ɗaya bane dangane da tasirin rage zafin jiki. Asfirin yafi tasiri da sauri a rage zafin jiki fiye da Paracetamol. Koyaya, akwai wasu bangarori na sakamakon waɗannan kwayoyi. Idan babu wasu fannoni na aikin waɗannan magunguna waɗanda ke da sha'awar mutum, yana iya ɗaukar kowane magani.

Amma idan kayi la'akari da wasu bangarorin aikin paracetamol da asfirin, to kowane magani zai fi dacewa da takamaiman yanayin. Da fari dai, ana amfani da paracetamol shine mafi kyawun magungunan antipyretic a duniya. Saboda haka, paracetamol an ba shi izinin watsawa da sarrafa kai a babban zafin jiki.

Asfirin zai iya rage zazzabi, amma zai iya zama magani mai haɗari. Babban haɗarin magungunan da ke dauke da Asfirin shine cewa suna aiki akan nau'ikan ƙwayoyin hanta iri ɗaya kamar wasu ƙwayoyin cuta waɗanda ke haifar da sanyi. Sakamakon haka, ƙwayoyin hanta suna shan wahala kuma suna da mummunan tasiri mara kyau a lokaci guda daga Aspirin da ƙwayoyin cuta. A ƙarƙashin tasirin asfirin da gubobi, ƙwayoyin hanta sun lalace, kuma mummunan cuta mai haɗari da ake kira Reye syndrome ta haɗu. An danganta wannan ilimin ne sakamakon rikicewar Asfirin.

Reye's syndrome cuta ce mai girman gaske, yawan mace-mace wanda ya kai 80 - 90%. Don haka, yin amfani da Asfirin don rage zafin jiki yana ɗaukar wasu haɗari. Amma Paracetamol bashi da irin wannan haɗarin. Saboda haka, zaɓin tsakanin Paracetamol da Aspirin, ban da kwatanta tasirin su, yana da wani fannin - matakin haɗarin. Asfirin yana da kyau a rage zafin jiki, amma yana iya haifar da rikicewar cuta, yayin da Paracetamol ya fi muni akan sarrafa zafi, amma yana da cikakken kariya kuma baya haifar da mutuwa koda da yawan zafin jiki. Wannan shine, zaɓin yana tsakanin ingantacciyar amma magani mai haɗari da ƙarancin tasiri, amma cikakkiyar lafiya.

Saboda yiwuwar kamuwa da cutar Reye ba aspirin ba da shawarar amfani da shi don rage yawan zafin jiki a cikin cututtukan hoto. Don rage yawan zafin jiki mai raunin kamuwa da cuta, ana bada shawara don amfani da shirye-shiryen Paracetamol. Kuma tare da kowane cututtukan ƙwayar cuta, irin su tonsillitis, pyelonephritis da sauransu, Asfirin yana da cikakken kariya kuma ana iya amfani dashi azaman maganin ƙwayar cuta mafi inganci.

Abinda zaba: Asfirin ko Paracetamol?

Idan kuna buƙatar zaɓar mafi kyawun maganin antipyretic, tambayar sau da yawa yakan tashi, wanda yafi kyau - Asfirin ko Paracetamol. Wadannan kwayoyi suna da alamu guda: suna rage zafin jiki na zazzabi (zazzabi), suna dakatar da matsakaici. Amma waɗannan magunguna suna da bangarori daban-daban na aiki, bambance-bambance a cikin hanyoyin aiwatarwa da contraindications.

Asfirin ko Paracetamol yana rage zafin jiki na zazzabi (zazzabi), dakatar da zafin matsakaici.

Halin Asfirin

Aspirin ne ya samar da kamfanin sarrafa magunguna na Jamus Bayer AG. Hanyar sashi na shirye-shiryen farin fararen allunan biconvex ne, wanda aka zana shi (giciye Bayer da rubutun ASPIRIN 0.5).

Sinadaran mai aiki: acetylsalicylic acid.

Mahalarta: sitaci na masara da celclose microcrystalline.

Asfirin ya ƙunshi Acetylsalicylic acid (ASA) a cikin adadin 500 MG / tab. Magungunan yana cikin rukunin magungunan magungunan anti-inflammatory anti-inflammatory (NSAIDs). Hakanan ASA shine narcotic analgesic da antipyretic, saboda yana shafar tsarin juyayi na tsakiya da cibiyoyin jin zafi da thermoregulation da ke cikin kwakwalwa. Acetylsalicylic acid nasa ne ga rukunin farko na NSAIDs, i.e. abu ne wanda ake iya magana da aiki na maganin kumburi.

Hanyar aiwatar da aiki na ASA ya dogara ne akan enzymes na cyclooxygenase (COX) wanda ba'a iya canzawa ba na nau'ikan 1 da na 2. Supparfafawa da samuwar COX-2 yana da tasirin farfaɗo da magunguna. Arfin aikin da ake kira COX-1 yana da sakamako masu yawa:

• toshewar kwayar prostaglandins (PG) da interleukins,
• rage cytoprotective Properties na kyallen takarda,
• hanawar kwayoyin cutar thrombooxygenase.

Tasirin ASA akan jiki ya dogara da kashi-kashi. Wannan yana nufin cewa magunguna na kwayoyin halitta sun bambanta dangane da yawan yau da kullun.

Ana amfani da ASA a cikin ƙananan allurai (30-325 mg / day) don hana cututtukan zuciya wanda zai iya lalacewa ta hanyar yawan haɗarin jini.

A wannan sashi, acetylsalicylic acid yana nuna kaddarorin antiaggregant: yana hana samuwar thromboxane A2, wanda ke haɓaka haɗarin platelet kuma yana haifar da vasoconstriction mai zafi.

Don sauƙaƙa zafin matsakaici da rage zafin jiki na jiki yayin zazzabi, matsakaiciyar allurai na ASA (1.5-2 g / day) suna da tasiri, waɗanda suke isa su toshe enzymes COX-2. Sesarancin allurai na acetylsalicylic acid (4-6 g / day) suna rage ƙarfin aikin kumburi, saboda ASA ba a cikin damuwa enzymes COX-1 enzymes, yana hana samuwar PG.

Lokacin amfani da ASA a cikin sashi wanda ya wuce 4 g / rana, ana inganta tasirin sa na uricosuric, kuma yin amfani da ƙanana da matsakaita na yau da kullun (har zuwa 4 g / rana) yana haifar da raguwa a cikin aikin urinary acid excretion.

Sakamakon sakamako na Asfirin shine gastrotoxicity dinsa, wanda ke faruwa saboda raguwa a cikin ƙwayar jijiyoyin da ke ciki da duodenal mucosa yayin hulɗa tare da acetylsalicylic acid. Rashin ikon sel ya murmure yana haifar da samuwar cututtukan erosive-ulcerative na bangon gastrointestinal fili.

Don rage gastrotoxicity na ASA, Bayer ta inganta Aspirin Cardio - allunan da ke ciki da kuma dragees. Wannan magani yana mai da hankali ne kan rigakafin cututtukan zuciya, sabili da haka, ASA tana dauke da shi a cikin ƙananan sashi (100 da 300 MG).

Yadda Paracetamol yake Aiki

Paracetamol a cikin nau'ikan allunan (200, 325 ko 500 mg / tab.) Ana samun su daga masana'antun daban-daban.

Abubuwan da ke aiki shine paracetamol (acetaminophen).

Mahalarta: sitaci na masara, sitacin dankalin turawa, gelatin, sodium croscarmellose, acid stearic.

Paracetamol yana cikin rukuni na biyu na NSAIDs (kwayoyi tare da rauni mai saurin kumburi). Acetaminophen asali ne na paraaminophenol. Hanyar aiwatar da wannan abu ya dogara da toshewar kwayar enzymes na COX da kuma hanawar kwayar GHG.

Rashin ƙarancin anti-mai kumburi saboda gaskiyar cewa peroxidases na ƙwayoyin ƙwayar jijiyoyin ƙwayar cuta suna hana toshewar ƙwayoyin cyclooxygenase (COX-2) wanda aikin Paracetamol ya haifar. Tasirin acetaminophen yana shimfidawa ne kawai ga tsarin juyayi na tsakiya da cibiyoyin thermoregulation da jin zafi a cikin kwakwalwa.

Amintaccen lafiyar Paracetamol na jijiyoyin mahaifa an yi bayani ne ta hanyar rashin hanawar kwayar halittar GHG a cikin kyallen takarda da adana kaddarorin gabobi. Sakamakon sakamako na acetaminophen yana da alaƙa da hepatotoxicity, sabili da haka, an sanya ƙwayar maganin ga mutanen da ke shan wahala daga barasa. Ana inganta tasirin mai guba a hanta tare da yin amfani da paracetamol tare da sauran NSAIDs ko tare da anticonvulsants.

Kwatanta Miyagun Kwayoyi

Wadannan magungunan suna cikin magungunan marasa narkewa da magungunan gargajiya, sannan kuma ana cikin su a cikin rukunin masu magungunan anti-steroidal anti-inflammatory (NSAIDs).

Magunguna daidai suke da kayan antipyretic kuma ana amfani dasu don rage zazzabi. Duk magungunan biyu ana ba su magunguna ba tare da takardar sayan magani ba.

Alamomin wadannan kwayoyi iri daya ne:

• raguwa a cikin zafin jiki na sama,
• kawar da matsakaici zafi
• raguwa a cikin yawan kumburi.

Contraindications na magungunan biyu sune:

• hanta, koda ko gajiyawar zuciya,
• karancin glucose-6-phosphate.

Ba a yin amfani da Asfirin don kula da yara saboda babban haɗarin haɓakar rashin hanta mai rauni a cikin yara masu kamuwa da cuta ko kwayar cutar Reye syndrome.

Mene ne bambanci

Magungunan suna da ayyukan anti-mai kumburi daban-daban: Paracetamol - mai rauni, Asfirin - ya ba da sanarwa.

Tunda abubuwanda ke aiki a cikin wadannan magunguna sun sha bamban, manyan abubuwanda suka sa gaba har ila yau sun sha bamban. Asfirin yana cikin cikin:

• basur na jini,
• sakaci na aortic aneurysm,
• ciwan ciki (ciki har da tarihi),
• babban hadarin kamuwa da ciki,
• rashin jituwa ga ASA da sauran NSAIDs,
• fuka-fuka-fitsari wanda yake rikitarwa ta hanyar hanci
• hawan jini
• saukar karfin jini
• karancin bitamin K

Duk da ƙayyadaddiyar ƙwayar cuta da cututtukan da ke haifar da ƙwayar cuta a jikin mutum, Aspirin ba a amfani da shi don kula da yara saboda babban haɗarin haɓakar cutar hanta mai ƙari a cikin yara masu kamuwa da kwayar cutar kwayar cuta (Reye's syndrome) Ba za ku iya amfani da miyagun ƙwayoyi tare da ulcers na ciki da duodenum kuma tare da babban haɗarin zub da jini na ciki. Aspirin yana contraindicated a cikin yara a karkashin shekaru 15, mata a lokacin daukar ciki (I da III trimesters), da kuma uwaye reno.

Ba'a bada shawarar paracetamol don amfani da:

• bashin,
• hoto ko bidiyo mai zagaya yanar gizo da sauri hepatitis
• lalacewar hanta.

Acetaminophen an dauke shi mafi aminci NSAID fiye da acetylsalicylic acid, saboda ba ya haifar da ci gaban Reye's syndrome, ba gastrotoxic ba, kuma baya rage thrombosis (kawai ASA yana da mallakar antiplatelet). Saboda haka, Paracetamol yana bada shawarar idan akwai abubuwa masu zuwa ga Aspirin:

• asma,
• tarihin ulcerative
• shekarun yara
• ciki
• lactation zamani.

Don haka, paracetamol na iya ɗauka ta hanyar yara, masu juna biyu da masu shayarwa.

Paracetamol yafi rinjayar tsarin juyayi na tsakiya da kuma aiki na jin zafi da cibiyoyin thermoregulation. Sabili da haka, wannan magani yana aiki azaman farfesa. Rashin rauni mai lalacewa na jiki yana bayyana ne kawai tare da ƙarancin abun ciki na ƙwayoyin peroxide a cikin kyallen (tare da osteoarthritis, rauni mai laushi), amma ba tare da rheumatism ba. Asfirin yana da tasiri don ciwo mai zafi na yau da kullun da ciwo mai zafi.

Don rage zazzabi yayin zazzabi kuma don rage ciwon kai da ciwon hakori, zai fi kyau ayi amfani da Paracetamol, saboda yana da karancin sakamako masu illa.

Wanne ne mafi arha

Allunan Paracetamol suna da arha sosai fiye da asfirin.

Wanne ya fi kyau - Asfirin ko Paracetamol

Zaɓin magani ya dogara da waɗannan dalilai:

• yanayin cutar (tare da kamuwa da cuta ko bidiyo mai zagaya yanar gizo da sauri, Aspirin yana contraindicated),
• shekaru haƙuri (Ba a amfani da Asfirin a cikin ilimin ƙwayoyin cuta),,
• makasudin magani (saukar da zafin jiki na jiki ko kuma yawan tasirin kumburi, hanawa thrombosis ko sauƙin jin zafi).

Don rigakafin cututtukan zuciya, Aspirin ne kawai ake amfani dashi, tunda ASA a cikin ƙananan allurai yana hana aikin thromboxane A2. Paracetamol ba shi da irin waɗannan kaddarorin.

Lokacin zabar analgesic, kuna buƙatar la'akari da yanayin jin zafi. Tare da ciwo na rheumatic da lalacewar kyallen na yanki, Paracetamol ba shi da tasiri, tunda tasirinsa yana iyakance ne ga tsarin juyayi na tsakiya. A irin waɗannan halayen, yana da kyau a yi amfani da Asfirin.

Don dakatar da tsarin kumburi a cikin majinyacin da ya balaga, amfanin Asfirin shima yafi tasiri, tunda yana da tasirin anti-mai kumburi sosai.

A zazzabi

A matsayin maganin antipyretic don zazzabi, duka Aspirin da Paracetamol ana amfani dasu.

An haramta asfirin don amfani da magungunan ƙwayoyin cuta saboda babban haɗarin haɓaka cutar Reye a cikin magance cututtukan cututtukan hoto ko yara. Don dakatar da jin zafi da rage zafin jiki a cikin yaro, yana da shawarar yin amfani da Paracetamol bisa ga umarnin.

Ra'ayin likitoci

Petrova A. Yu., Likitan likitanci: "Don lura da yara, zai fi kyau a yi amfani da shirye-shiryen da ke ɗauke da paracetamol a cikin siram (Panadol)."

Kim L. I., mai ilimin tauhidi: “Wadannan kwayoyi ba sa maganin cutar da ke haifar da cuta - kawai suna rage yanayin mai haƙuri ne. Kuna iya amfani da waɗannan magunguna ba tare da magani da ya dace ba har tsawon kwanaki 3. Idan bayyanar cututtukan sanyi ba ta tafi ba, to tsarin garkuwar jiki baya iya kawar da tsarin kumburin da kansa. Don guje wa rikice-rikice, kuna buƙatar ganin likita. ”

Binciken haƙuri game da Asfirin da Paracetamol

Alina, ɗan shekara 24, Ufa: “Asfirin magani ne mai tsada wanda yake da magunguna da cututtukan da suke da yawa. Paracetamol shima ba cutarwa bane, amma lafiyayye. "

Oleg, dan shekara 36, ​​Omsk: “Ina amfani da Asfirin (allunan dake narkewa) don maganin ciwon kai ko mura. Ban lura da wani sakamako masu illa ba. ”

Halayyar Paracetamol

Magani yana taimakawa rage zafin jiki. Yana kawar da jin zafi, yana dakatar da ci gaban aikin kumburi. Aiki mai aiki a cikin abun da ke ciki shine paracetamol. Yana hana samuwar prostaglandins kuma yana aiki akan cibiyar thermoregulation a cikin diencephalon. Kayan aiki yana hana bayyanar jin zafi, yana kawar da zazzabi. Yana da ƙananan tasirin anti-mai kumburi.

Adana magungunan don jin zafi a baya, tsokoki, gidajen abinci. Yana sauƙaƙa ciwon kai, rashin jin daɗi a cikin ciki yayin haila. An ba da shawarar don mura da mura don rage yawan zafin jiki da inganta lafiyar gaba ɗaya. Yanayin aiki yana contraindicated a cikin wadannan cututtuka da yanayi:

• ciki
• nono
• barasa giya
• mummunan lalacewar hanta da kodan,
• cututtukan jini
• raguwa a cikin tantanin jini,
• karancin glucose-6-phosphate.

A miyagun ƙwayoyi na iya haifar da rashin lafiyan halayen. A cikin lokuta mafi ƙarancin gaske, anaphylaxis, tashin zuciya, bronchospasm, urticaria, da raunin ciki bayan ana lura da su. Cikakke daga narkewa. Abubuwan da ke aiki suna ɗaure zuwa sunadarai, suna yin biotransformation a cikin hanta kuma an keɓance shi a cikin yanayin metabolites marasa aiki a cikin fitsari tsawon awanni 8-10. Ba ya cutar da ma'aunin ruwa da gishiri a jiki. Zai fara aiki tsakanin mintuna 15-30.

Wanne ya fi kyau - Paracetamol ko Asfirin

Paracetamol amintacce ne ga tsarin narkewar abinci. Ana iya ɗauka ko da a kan tushen ƙwayar peptic, kodayake hanta tana fama da miyagun ƙwayoyi.The miyagun ƙwayoyi yana da rauni mai tasiri akan jiki, don haka yawancin lokuta marasa lafiya suna barin ra'ayi game da ƙarancin aiki.Tare da ciwo mai zafi, zazzabi da kumburi, zai fi kyau ɗaukar acid acetylsalicylic.

Tare da mura

Don mura, babban ya fi jin daɗin ɗaukar Acetylsalicylic acid. Magani na iya magance zafi, kumburi da jikin sa da sauri kadan. Don haɓaka tasiri, likita ya ba da izini ga ma'aikatan rigakafi.

A cikin ƙuruciya, zai fi kyau ɗaukar Paracetamol. Yana aiki da hankali, saboda haka ba za ku iya jin tsoron mummunan sakamako masu illa ba. Ba da asfirin ga yara 'yan ƙasa 15. Ya kamata a ɗauka gwargwadon sashi wanda aka nuna a cikin umarnin kuma kawai in babu contraindications.

Binciken haƙuri game da Paracetamol da Aspirin

Anna, 29 years old, Murmansk

Asfirin yafi kyau fiye da Paracetamol. Na dauka tare da ARVI. Zazzabi ya ragu a cikin awa daya zuwa dabi'un al'ada. Ciwon kai ya tafi kadan kuma yanayin gaba daya yana inganta. Na yarda a lokuta na gaggawa, saboda miyagun ƙwayoyi suna cutar da jiki tare da amfani da kullun.

Kristina, mai shekara 35, Samara

Paracetamol da aka bai wa jariri. Heat yana rushewa a hankali, amma na dogon lokaci. Yana da mafi ƙarancin contraindications da sakamako masu illa. Tare tare da antipyretics, kuna buƙatar shan shaye da yawa kuma ku ɗauki bitamin.