Protaphane® HM (Protaphane® HM)

Protafan ® HM Penfill ®

Aikin magunguna

Yana hulɗa tare da takamaiman mai samar da ƙwayar plasma membrane kuma yana shiga cikin tantanin halitta, inda yake kunna ƙwayar phosphorylation na ƙwayoyin salula, yana motsa glycogen synthetase, pyruvate dehydrogenase, hexokinase, yana hana adipose nama lipase da lipoprotein lipase. A hade tare da takamaiman mai karɓa, yana sauƙaƙa shigarwar glucose a cikin sel, yana haɓaka haɗakarwa ta hanyar kyallen takarda kuma yana inganta juyawa zuwa glycogen. Muscleara yawan ƙwayar jijiyar glycogen, yana ƙarfafa ƙwayar peptide.

Clinical Pharmacology

Tasirin yana inganta 1,5 hours bayan sc gwamnatin, ya kai matsakaici bayan sa'o'i 4-12 kuma yana ɗaukar awanni 24. Ana amfani da Protafan NM Penfill don ciwon sukari na insulin-insulin a matsayin basal insulin a hade tare da insulin-gajeran aiki, ga insulin-dogara-kamar na monotherapy , kuma a hade tare da insulins masu aiki da sauri.

Haɗa kai

Tasirin hypoglycemic yana haɓaka ta hanyar acetylsalicylic acid, barasa, alpha da beta blockers, amphetamine, steroids anabolic, clofibrate, cyclophosphamide, phenfluramine, fluoxetine, ifosfamide, MAO inhibitors, methyldopa, tetracycline, trifamaxigin triincigin, trifamazigin triincigin thiazides), glucocorticoids, heparin, maganin hana haihuwa, isoniazid, carbonate lithium, nicotinic acid, phenothiazines, sympathomimetics, tricyclic antidepressants.

Sashi da gudanarwa

Protafan ® HM Penfill ®

P / c. Magungunan an yi niyya ne don gudanar da tsarin mulki na ƙasa. Dakatarwar insulin ba za a iya shigar da / ciki ba.

An zaɓi kashi na miyagun ƙwayoyi daban-daban, la'akari da bukatun mai haƙuri. Yawanci, bukatun insulin tsakanin 0.3 da 1 IU / kg / rana. Bukatar yau da kullun don insulin na iya zama mafi girma a cikin marasa lafiya tare da juriya na insulin (alal misali, yayin balaga, har ma a cikin marasa lafiya tare da kiba), da ƙananan cikin marasa lafiya tare da ragowar insulin na insulin.

Ana iya amfani da Protafan ® NM duka a cikin monotherapy kuma a hade tare da insulin mai sauri ko gajere.

Protafan ® NM mafi yawanci ana gudanar dashi a ƙarƙashin cinya. Idan ya dace, to za a iya yin allura a jikin bangon gaban ciki, a yankin gluteal ko kuma a yankin ƙyallen ƙyallen kafada. Tare da gabatarwar miyagun ƙwayoyi a cikin yankin cinya, an lura da hankali sosai fiye da gabatarwar zuwa wasu yankuna. Idan allurar ta kasance cikin yalwar fatar fata, za a rage girman hadarin da ke tattare da gudanar da maganin ta hanyar ƙwayar cuta.

Dole ne allurar ta kasance a cikin fata na akalla awanni 6, wanda ke tabbatar da cikakken kashi. Wajibi ne a canza wurin allura a koyaushe a cikin yankin ilimin halittar jiki don hana ci gaban lipodystrophy.

An tsara Protafan ® NM Penfill ® don amfani da tsarin allurar insulin Novo Nordisk da allurar NovoFine ® ko NovoTvist ®. Cikakken shawarwari don amfani da gudanar da maganin ya kamata a lura.

Cututtukan da ke haɗuwa, musamman masu kamuwa da cuta tare da zazzabi, yawanci suna ƙaruwa da buƙatar jikin mutum na insulin. Hakanan ana iya buƙatar gyaran gyaran jiki idan mai haƙuri yana da cututtukan cututtukan da suka shafi kodan, hanta, nakasasshen aikin adrenal, glandar glandonto ko glandar glandar ku. Buƙatar daidaitawa na iya faruwa yayin canzawar aiki na zahiri ko kuma irin abincin da mai haƙuri ya saba samu. Zai yiwu a buƙaci daidaitawa yayin canja wurin mai haƙuri daga nau'in insulin zuwa wani

Yawan abin sama da ya kamata

Kwayar cutar haɓakar hauhawar jini (gumi mai sanyi, guguwar bugun zuciya, rawar jiki, yunwar, tashin hankali, tashin hankali, ciwon kai, ciwon kai, rashin motsi, rashin motsi, magana da rashin hangen nesa, rashin ƙarfi). Babban tsananin rashin ƙarfi na iya haifar da rashi na ɗan lokaci ko na dindindin na aikin kwakwalwa, coma, da mutuwa.

Jiyya: sukari ko bayani na glucose a ciki (idan mai haƙuri yana sane), s / c, i / m ko iv - glucagon ko iv - glucose.

Fom ɗin saki

Dakatarwa don gudanarwar subcutaneous, 100 IU / ml (vials). A cikin kwalaben gilashin gilashin hydrolytic aji 1, an haɗa shi da masu dakatarwa daga bromobutyl / polyisolorida roba da ƙananan filastik, 10 ml, a cikin fakitin kwali 1 fl.

Dakatarwa don gudanarwar subcutaneous, 100 IU / ml (katako). A cikin gilashin gilashin gilashin Miliyan 3, gilashin, katako 5 a cikin blisters, 1 blister pack a cikin kwali.