Chlorhexidine 0.05 Sakamakon ciwon sukari

Chlorhexidine - magani ne, maganin antiseptik, cikin ƙoshin sashi na amfani ana amfani dashi ta hanyar babban bigire (Chlorhexidini bigluconas). An yi amfani da Chlorhexidine cikin maganin antiseptik na waje da magunguna na sama da shekaru 60.

0.05% ruwa mai ruwa a cikin ruwa na 100 ml.

0.5% maganin barasa a cikin miliyan 100 vials.

Chlorhexidine


Kwayar kemikal
IUPAC	N ',N '' '' ''-hexane-1,6-diylbisN- (4-chlorophenyl) (imidodicicbonbonic diamide)
Tsarin gaba ɗaya	C₂₂H₃₀Cl₂N₁₀
Taro na Molar	505.446 g / mol
Cas	55-56-1
BugaI	5353524
Bankin Drug	APRD00545
Rarrabawa
ATX	A01AB03 B05CA02, D08AC02, D09AA12, R02AA05, S01AX09, S02AA09, S03AA04
Siffofin Sashi
Hanyar gudanarwa
Kayan shafawa d
Wasu sunaye
"Sebidin", "Bala'i", "Heleraon", "Chlorhexidine bigluconate"
Fayilolin Mai amfani da Wikimedia

Yana da mahimmanci a lura cewa tsawon lokacin amfani da kasuwanci da binciken kimiyya na chlorhexidine, babu ɗayansu da zai iya tabbatar da yiwuwar samar da ƙananan ƙwayoyin cuta mai ɗaukar ƙwayar chlorhexidine. Koyaya, bisa ga binciken da aka yi kwanan nan, yin amfani da chlorhexidine na iya haifar da juriya a cikin ƙwayoyin cuta (musamman, juriya na Klebsiella pneumoniae zuwa Colistin).

Chemically, asalin abu ne wanda yake dauke da abubuwan da ake amfani da su na biguanide. Tsarin yana kusa da bigumal. Hanyar aikin chlorhexidine shine yin hulɗa tare da rukunin phosphate akan farfajiya, yana haifar da canji a cikin ma'aunin osmotic, take hakkin amincin tantanin halitta da mutuwarsa.

Chlorhexidine magani ne mai maganin antiseptik wanda ke aiki da hakoran-gram-aerobic da kwayoyin anaerobic (Treponema pall>. Magungunan yana da kwanciyar hankali kuma bayan sarrafa fata (hannaye, filin tiyata, da dai sauransu) ya kasance a kansa a cikin wani adadin, wanda ya ci gaba da ba da sakamako mai ƙwayar cuta.

A miyagun ƙwayoyi ya kasance aiki a gaban jini, mugunya, ko da yake da ɗan rage. Wasu nau'ikan Pseudomonas spp., Proteus spp. Suna da rauni sosai ga chlorhexidine, nau'ikan ƙwayoyin cuta na acid masu juriya. Chlorhexidine yana aiki akan ƙwayoyin ƙwayoyin cuta kawai a yanayin zafi.

Ana amfani dasu don kula da filin tiyata da hannayen likitan, da lalata kayan aikin tiyata, da kuma don hanyoyin purulent-septic (wanke raunukan tiyata, mafitsara, da sauransu) da kuma rigakafin cututtukan da ke ɗaukar jima'i (syphilis, gonorrhea, trichomoniasis). Abubuwan chlorhexidine bigluconate ana samunsu azaman maganin cikas na kashi 20%. Magungunan da ke shirye don amfani da shi ba shi da wata hanyar da ta dace da ruwa mai ruwa-ruwa ko ruwa. Don haka, don sarrafa filin tiyata, an magance dillancin 20% tare da barasa na 70% a cikin 1:40. Sakamakon 0.5% na maganin maye-giya na chlorhexidine bigluconate ana bi da shi tare da filin tiyata sau 2 tare da tazara na minti 2. Don sanya kayan kida da sauri, yi amfani da maganin guda don mintuna 5. Ana amfani da maganin magance ruwa na 0,5% don magance raunuka da ƙonewa, maganin giya na 0,5% ko maganin shafawa na 1% don amfani da hannu. Lokacin amfani da miyagun ƙwayoyi don kula da hannayen tiyata, yana iya haifar da bushewa da itching na fata, dermatitis, mangwalan fata na hannayen a tsakanin mintuna 3-5 shima hakan zai yiwu.

posaya daga cikin maganin ya ƙunshi 0.016 g na chlorhexidine bigluconate

Maganin kumburin ciki (na jarirai)

posaya daga cikin maganin ya ƙunshi 0.008 g na chlorhexidine bigluconate.
Gel don amfanin gida da na waje na 0.5% (100 g na gel ya ƙunshi 0.5 g na chlorhexidine bigluconate).
Magani don amfani da waje na 0.05% (100 ml na ruwa tsarkakakken ya ƙunshi maganin chlorhexidine bigluconate 20% - 0.25 ml).

Hanyoyin warware ruwan roba:

0.2% maganin warware ruwa
0.1% maganin chlorhexidine bigluconate a cikin ethanol (Eludryl).

Chlorhexidine azaman prophylactic da wakili mai warkewa ana amfani da shi ne ta sama da saman. Ana amfani da 0.05%, 0.2% da 0,5% na ruwa mai ruwa a cikin hanyar ban ruwa, rinsing da aikace-aikacen - 5-10 ml na mafita ana amfani da saman fata na fata ko mucous membranes tare da bayyanar mintuna 1-3 2-3 a rana sau (a kan swab ko ta ban ruwa). Ana aiwatar da kayan aikin likitanci da aikin saman tare da soso mai tsabta da aka jika tare da maganin maganin cututtukan ƙwayar cuta, ko ta soaking. Don rigakafin cututtukan da ake kamuwa da ita ta hanyar jima'i, ƙwayar tana da tasiri idan an yi amfani da ita ba 2 ba bayan 2 sa'o'i bayan yin jima'i. Yin amfani da bututun ƙarfe, saka abun ciki na murfin cikin urethra na maza (2-3 ml), mata (1-2 ml) da cikin farjin (5-10 ml) na mintina 2-3. Don aiwatar da fata na fata na ciki na cinya, pubis, gabobi. Bayan aikin, kada a yi saurin awanni 2. Ana aiwatar da cikakkiyar maganin cututtukan ƙwayar cuta da urethroprostatitis ta hanyar allura 2-3 ml na maganin 0.05% na chlorhexidine babban maganin sau 1-2 a rana zuwa cikin urethra, hanya ita ce kwana 10, ana tsara hanyoyin kowace rana. Intravaginally, 1 suppository sau 3-4 a rana don kwanaki 7-20, gwargwadon yanayin cutar. Kurkura da gel da ake amfani da shi a kan kullun ana sanya su sau 2-3 a rana. Tufafin: cire fim ɗin kariya daga facin ba tare da taɓa bandeji da yatsunku ba, ku shafa wa yankin da ya lalace na fata. Latsa geffin patch din tare da yatsunsu domin sashen m na facin ya gyara bandeji.

A cikin 2013, WHO ta haɗa da maganin 7% na chlorhexidine bigluconate a cikin jerin magunguna masu mahimmanci. Dangane da shawarwarin WHO, ana kula da igiyar cibiyar (injin mara lafiya) tare da maganin 7%, wanda zai rage yiwuwar kamuwa da cuta a cikin jarirai.

lura da cututtukan farji (ƙwayar ƙwayar cuta na kwayan cuta, trichomoniasis, ba takamaiman, hade da cututtukan fata)
rigakafin gaggawa na mutum na kamuwa da cututtukan jima'i (syphilis, gonorrhea, trichomoniasis, chlamydia, ureaplasmosis)
Gyaran wurin aikin haihuwa don shirya yadda ake bayarwa da sarrafa lokacin haihuwa a cikin mata masu haɗarin kamuwa da cututtukan fata da kumburi

Za'a iya amfani da magungunan ƙwayar cuta a cikin dukkan lokutan uku na ciki da lokacin shayarwa. Magungunan ƙwayoyin cuta a hankali suna shafar membrane, yayin da suke riƙe microflora na farji na al'ada. Ba a ayyana asalin ranar 3375 ba

Maganin kumburin ciki (na jarirai)

Gel don amfanin gida da waje 0.5%

lura da raunuka, abrasions, scratches, konewa, karce
magani da rigakafin cututtukan fata da fata membranes
amfani da ilimin hakora (gingivitis, stomatitis da periodontitis)
lura da kuraje (a matsayin wani ɓangare na hadaddun far)
fata na fata bayan hanyoyin kwaskwarima (sokin, jarfa, depilation)
kariya daga kwayoyi a wuraren jama'a, a yanayi
0.5% maganin barasa na chlorhexidine

kula da hannun likitocin, likitoci, fata na wuraren aiki da kuma allura
lura da raunin da ya faru tare da bayyanar mintuna 1-2
watsi da na'urorin lafiya, kayan aikin haƙori, saman na'urorin
0.05% maganin maganin ruwa na chlorhexidine bigluconate

wanke raunuka, abrasions, scrap, konewa, karce, kwari kwari
amfani da ilimin hakora (gingivitis, stomatitis, alveolitis, periodontitis)
lura da cututtukan ENT (pharyngitis, laryngitis, tonsillitis, otitis media)
kariya daga kwayoyi a wuraren jama'a, a yanayi
rigakafin kamuwa da cututtukan jima'i
0.2% maganin magance ruwa na chlorhexidine bigluconate

lura da farfadowa da ƙwayar cuta a cikin ilimin mahaifa, urology yayin hanyoyin bincike na likita
disinfection na m Dentures
Maganin 0,5% na chlorhexidine bigluconate

lura da raunuka da ƙonewa, lura da kamuwa da scuffs da fasa na fata, bude mucous membranes
haifuwa na kayan likita a zazzabi na 70 ° C
1% maganin maganin ruwa na chlorhexidine bigluconate

na gama gari na ɗakuna, kayan aikin tsabta, da sauransu.
lura da filin tiyata da hannayen mai tiyata kafin tiyata, rigar fata, lura da aikin asibiti da kuma raunuka
Hypersensitivity ga miyagun ƙwayoyi, dermatitis, halayen rashin lafiyan halayen. Yin amfani da aidin a lokaci guda wanda ba a ke so shi ba don guje wa ci gaban cututtukan fata. Kada a yi amfani da mafita na Chlorhexidine don bi da maganin haɗin kai kuma a matse cavis ɗin.
Tsanani Shirya
Yi amfani da hankali tare da ƙuruciya.
Ana amfani da Chlorhexidine don hana STDs kawai azaman matakin gaggawa (kwaroron roba, saduwa da jima'i). Abubuwan da aka saba da su akai-akai na chlorhexidine a cikin urethra na iya haifar da ƙonewar sinadarai (musamman tare da shakkuwar mutum ga miyagun ƙwayoyi), wanda a ƙarshe zai haifar da irin wannan rikitaccen rikicewar kamar tsananin urethral. Ba a ayyana asalin ranar 1142 ba .
Abubuwan Tausayi na Vaginal. Allergic halayen, itching, faruwa bayan dawo da magani mai yiwuwa ne. Zubar da jini na abubuwa daban-daban mai yiwuwa ne.
Gel. Allergic halayen, bushe fata, itching, discoloration na fata, dermatitis, stickiness na fata na hannayensu (3-7 min) lokacin amfani da gel, photoensitivity (sabon abu na kara ji na jiki (mafi yawan lokuta fata da mucous membranes) zuwa ultraviolet radiation). A cikin lura da gingivitis - ɓarna da haƙoran haƙoran haƙora, ƙwayar tartar, ɗanɗano damuwa. Ruwan enamel da adana kalifa yana faruwa idan anyi amfani da magani na tsawan lokaci.
Magani. Da wuya mutane ke haifar da rashin lafiyan halayen, ƙaiƙayi, wucewa bayan an daina maganin.
Idan haɗari ya shigo cikin miyagun ƙwayoyi, to kusan ba a cika shi ba; ana nuna ƙoshin ciki ta hanyar amfani da madara, sabulu mai laushi, gelatin ko ƙwai mai ƙwai.
Babu takamaiman maganin rigakafi, sabili da haka, idan akwai sakamako masu illa, ana aiwatar da maganin tiyata.

Ba a bada shawarar amfani da kwaskwarima tare da aidin.
Chlorhexidine bai dace da sabulu waɗanda ke ɗauke da ƙungiyar anionic (saponins, sodium lauryl sulfate, sulfonic acid, sodium carboxymethyl cellulose) da soaps. Kasancewar sabulu na iya hana chlorhexidine, don haka dole ne a wanke ragowar sabulu kafin amfani da magani.
Yana samar da fili mai guba lokacin da aka haɗe shi da sodium hypochlorite (NaOCl) - para-chloraniline (n-NH₂C₆H₄Cl). Akwai shaidun cewa parachloraniline mai guba ce (Burkhardt-Holm et al., 1999) cikakkun hanyoyin haɗin yanar gizo kuma yana iya haifar da samuwar methemoglobin.
Ethanol yana haɓaka tasiri na chlorhexidine.

Magungunan mara jijiyya. Kwayar ta waje ba ta da tasiri da kuma haƙurin ƙwayar jijiyoyi, tunda ana amfani da maganin ta hanyar cikin ciki.
Magani da gel. Guji shigar da miyagun ƙwayoyi a cikin raunin marasa lafiya tare da budewar craniocerebral rauni, raunin kashin kashin baya, karkatar da ƙwayar ƙwayar cuta ta tympanic. Idan mafita ya shiga cikin mucous membranes na ido, ya kamata a wanke su da sauri kuma da ruwa sosai. Takaddun bayanan Tsaro (MSDS) na babban ƙwaƙwalwar ƙwayar chlorhexidine.
Thearfafa ayyukan hypochlorite da ke fitar da abubuwa a cikin kyallen takarda waɗanda a baya suna haɗuwa da shirye-shiryen da ke tattare da chlorhexidine na iya bayar da tasu gudummawar bayyanar launin toka a kansu. Sakamakon ƙwayar cuta yana ƙaruwa tare da ƙara yawan zafin jiki na maganin. A yanayin zafi sama da 100 ° C, miyagun ƙwayoyi sun lalata.
Magungunan ruwa mai narkewa na chlorhexidine zasu iya bazu (musamman lokacin mai zafi da alkaline pH) tare da kirkirar adadin 4-chloroaniline, wanda ke da kaddarorin carcinogenic.
An bayyana shari'ar a ina? ci gaban methemoglobinemia da cyanosis a cikin jarirai a cikin mahaifa saboda guba 4-chloroaniline Ba a ayyana asalin ranar 284 ba . An sanya na'urar wankin tare da hura wuta tare da maganin chlorhexidine, wanda idan yayi zafi, zai iya bazu zuwa 4-chloroaniline.