Gluconorm - magani ne na nau'in ciwon sukari na 2

Ana samun magungunan a cikin nau'ikan farin zagaye Allunan, convex a garesu. An tattara raka'a na magani a cikin fakiti mai bakin ciki guda 10 kowannensu. Katin ya ƙunshi blister 4. Hakanan akwai kwantena tare da blister 2 na allunan 20.

Kwayar gluconorm ta ƙunshi abubuwa masu aiki:

• metformin hydrochloride - 400 MG,
• glibenclamide - 2.5 MG.

Don haɓaka bioavailability, abun da ke ciki ya haɗa da abubuwan taimako: gelatin, glycerol, diethyl phthalate, croscarmellose sodium, sitaci masara, talc, magnesium stearate, colloidal silicon dioxide, microcrystalline cellulose.

Aikin magunguna

Yana haɗuwa da magungunan cututtukan hypoglycemic daga rukunin magungunan ƙwayoyin cuta: metformin da glibenclamide. Latterarshen yana nufin keɓaɓɓen abubuwan tarihin na ƙarni na biyu. Theara yawan haɓakar glucose na ƙwayoyin beta na pancreatic, yana haifar da karuwar insulin insulin a cikin mataki na biyu. Yana ƙarfafa ƙwayar insulin da ƙwanƙolin abin da ta ɗaure don lalata ƙwayoyin. Glibenclamide yana haɓaka haɗarin sukari ta hanyar tsoka da ƙwayoyin hanta, yayin da a lokaci guda yana hana fashewar fitsari ta hanyar ƙwayar lipase.

Metformin ya fito ne daga rukuni na biguanides. An tsara shi don haɓaka hankali da haɓaka tasirin gulukos ta hanyar kyallen tsinkaye. Abubuwan da ke aiki suna rage adadin lipoproteins mai yawa da triglycerides, suna da tasirin gaske akan furotin mai narkewa a cikin jini. Yana hana samuwar kwalayen cholesterol ba tare da yin wani tasiri ba.

Glibenclamide

Bayan gudanar da baki, adsorption na glibenclamide a cikin ƙananan hanji shine 50-85%. Abubuwan ya kai matsayin mafi girman hankali a cikin jini bayan sa'o'i 1.5-2. Yana ɗaukar nauyin protein na 95%.

Glibenclamide kusan an canza shi gaba daya a cikin hanta tare da samuwar metabolites guda biyu wadanda basa aiki. An ware shi daban ta hanyar kodan da hanjin kansa. Rabin rayuwar yana daga awa 3 zuwa 16.

Lokacin da ya shiga cikin jijiyoyin ciki, cikakken sha yana faruwa. Bioavailability ya kai kashi 50-60%. Yawan sha yana ragewa tare da abinci guda. 30% na metformin an keɓe cikin feces. Sauran an rarraba cikin sauri a cikin kyallen takarda ba tare da ɗauka ga furotin plasma ba.

Rabin rayuwar ya kai awoyi 9-12. Kusan ba sa hannu a cikin metabolism. Cire metformin daga jiki yana gudana ne ta hanyar kodan.

Ana amfani da gluconorm ta marasa lafiya masu fama da ciwon sukari na 2:

• tare da rashin ingancin abinci da aikin mutum,
• tare da gazawar maganin metformin da ya gabata a cikin mutane tare da matakan sukari da aka sarrafa.

An ba da shawarar don amfani da mutane sama da 18 shekara.

Contraindications

An haramta amfani da Gluconorm don amfani:

• Nau'in mara lafiyar masu cutar siga
• mata yayin daukar ciki da lactation,
• tare da kashi daya na miconazole,
• a gaban tsananin na koda dysfunction,
• mutane masu karancin sukari
• marasa lafiya da cututtukan porphyrin da cutar cututtukan fata suka kama,
• a cikin aikin bayan aikin yayin tiyata don kawar da ƙonewa na babban yanki,
• tare da hanta da koda, ga kuma yanayin da yake kai su (keta haddin gishirin-ruwa, tsawaita tsawon lokaci, rashin aiki na zuciya da gazawa),
• tare da guba jiki da gubobi,
• kwana biyu kafin da bayan daukar hoto ta amfani da wakili, wanda ya hada da aidin,
• tare da tsananin lactic acidosis,
• batun abinci mai kalori mai kadan, wanda mutum zai ci kasa da kcal 1000 a rana,
• a gaban halayen rashin lafiyan ga metformin da abubuwan taimako.

Hakanan ana bada kariya a hankali idan zazzabi, dysfunction da atrophy na glandon adrenal, idan akwai aiki mai rauni na huhun ciki da huhun hancin ku.

Umarnin don amfani (sashi)

Gluconorm an yi shi ne don gudanar da maganin baka. An zabi sashi na miyagun ƙwayoyi daban-daban ta likitan halartar. Tushen nadin yau da kullun sune sakamakon binciken.

A farkon magani, an wajabta mai haƙuri 1 kwamfutar hannu a rana. Bayan kwanaki 7-14, an daidaita yawan maganin a daidai da sakamakon bincike game da matakin glucose a cikin jini. Matsakaicin kashi bai kamata ya zarce allunan 5 a kowace rana ba.

Game da sauyawa na haɗuwa na baya na metformin da glibenclamide, ana ba allunan 1-2 na Gluconorm ga mai haƙuri, gwargwadon satin da ya gabata na kowane kashi.

Side effects

Daga gefen metabolism na metabolism, a cikin mafi yawan lokuta, hypoglycemia yana haɓaka.

Tare da sakamako masu illa a cikin gastrointestinal fili da hanta, mai haƙuri na iya jin tashin zuciya, amai, jin zafi a cikin yankin na epigastric, rashin ci, "dandalin" ƙarfe "a cikin bakin. A cikin lokuta mafi wuya, an bayyana jaundice, ayyukan enzymes na hanta yana ƙaruwa, hepatitis yana haɓaka.

Leukopenia, thrombocytopenia, erythrocytopenia, agranulocytosis, hemolytic ko megaloblastic anemia, pancytopenia suna haɓaka lokacin da sakamako masu illa daga tsarin cututtukan jini na jini.

Tsarin juyayi na tsakiya na iya amsawa tare da ciwon kai, tsananin rauni, rauni, da kuma ƙaruwa gajiya. A cikin lokuta mafi wuya, ana lura da paresis, rikicewar hankali.

Allergy ya bayyana a cikin nau'in halayen cututtukan cututtukan fata:

• cututtukan mahaifa
• erythema
• fata ƙaiƙayi
• zazzabi
• arthralgia
• proteinuria.

Daga gefen metabolism, lactic acidosis mai yiwuwa ne.

Sauran: amsawar m na rashin haƙuri bayan shan giya, wanda aka bayyana ta rikitarwa na jijiyoyin jini da gabobin jiki (disulfiram-like dauki: amai, jin zafi a fuska da babba jiki, tachycardia, dizziness, ciwon kai).

Yawan abin sama da ya kamata

Tare da yawan shaye-shayen ƙwayoyi, alamu masu zuwa suna bayyana nasara:

• yunwa
• karuwa da danshi,
• zuciya palpitations,
• girgiza (rawar jiki) na wata gabar jiki,
• damuwa da bacin rai
• ciwon kai
• rashin bacci
• haushi
• daukar hoto, ba zai iya gani ba da kuma aikin magana.

Idan mai haƙuri yana da hankali, ana buƙatar sukari. A cikin yanayin da ba a sani ba, ya kamata a gudanar da 1-2 ml na glucagon ko dextrose na ciki. Lokacin dawo da cikakken sani, mai haƙuri dole ne ya ɗauki abincin da ke ɗauke da ƙwayoyin carbohydrates.

Saboda kasancewar metformin a cikin "Gluconorm", mai haƙuri na iya haɓaka lactic acidosis. Wannan yanayin yana buƙatar kulawa da gaggawa na likita da magani na inpatient ta hanyar hemodialysis.

Hulɗa da ƙwayoyi

Tsokane matakin karawa na iya:

• Allourinza,
• wasu magunguna na hypoglycemic (gungun biguanide, insulin, acarbose),
• alli tubule blockers,
• kwayoyin hana kwayoyi (monoamine oxidase inhibitors)
• Coumarin anticoagulants,
• Salamamara
• magungunan anabolic steroid
• haɓakar sulfonamides,
• karafarini,
• tetracycline
• fenfluramine,
• mai kyalli
• pyridoxine
• guanethidine,
• skwarin
• ACE inhibitors (enalapril, captopril),
• dimbin yawa na karɓa H2 mai tallatawa (cimetidine),
• antifungal (miconazole, fluconazole) da magungunan tarin fuka,
• Chloramphenicol.

Glucocorticosteroids, barbiturates, antiepileptics (phenytoin), acetazolamide, thiazides, chlorthalidone, furosemide, triamterene, asparaginase, baclofen, danazol, diazoxide, isoniazid, morphine, ritodrine, salbutamol, terbutaline, glucagon, rifampicin, thyroid hormones, lithium salts iya raunana tasirin miyagun ƙwayoyi.

Abubuwan hana rigakafi, nicotinic acid, estrogens da chlorpromazine suna rage tasirin maganin.

Ganin irin raguwar dissociation da karuwar reabsorption na glibenclamide, ammonium chloride, alli chloride, ascorbic acid (a babban sashi) inganta aikin miyagun ƙwayoyi.

"Furosemide" yana ƙara yawan maida hankali na metformin da kashi 22%. "Nifedipine" yana haɓaka sha, amma mafi girman haɗarinsa yana rage jinkirin abubuwa masu aiki.

Amyloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren da vancomycin daga yakin cationic jere don tsarin jigilar tubular, tare da tsawan amfani da kara yawan metformin da kashi 60%.

Umarni na musamman

Ana buƙatar cire magunguna da maye gurbi tare da maganin insulin idan ana fama da matsananciyar wahala bayan aikin tiyata, raunin da ya faru, ƙonewa babban yanki, harma da kamuwa da cuta na jiki, tare da zazzabi.

A lokacin jiyya, ana buƙatar saka idanu na yau da kullum a cikin glucose.

Tare da tsawaita azumi, kazalika da shan barasa, haɗarin raguwa mai yawa a cikin matakan glucose na jini yana ƙaruwa. Dangane da bincike, a lokacin magani, ba a yarda da barasa ba. Tare da wuce gona da iri ta jiki da ta motsa jiki, ana daidaita sashin maganin, abincin ya canza.

Kwana biyu kafin a fara aikin tiyata ko kuma maganin sarrafa ruwan aidin wanda yake dauke da kayan maye, an soke maganin. Ci gaba bayan awa 48 bayan karatun.

A lokacin jiyya, ya zama dole a guji wasu ayyuka daban-daban da ke buƙatar nishaɗi da haɓakar hanzarin motsi. Ba da shawarar tuki.

Haihuwa da lactation

An haramta amfani da miyagun ƙwayoyi don amfani yayin daukar ciki. Don lokacin shiryawa da zama, an soke shi. Gluconorm ya maye gurbin maganin insulin.

Mata kuma yayin shayarwa an kuma haramtawa shan maganin saboda shigar da metformin cikin madara. Iyaye mata suna buƙatar canzawa zuwa farjin insulin. Idan wannan matakin ba zai yiwu ba, dakatar da shayarwa.

Kwatanta tare da analogues

MUHIMMIYA! Haramun ne a aiwatar da wani maye gurbin Gluconorm tare da wasu kwayoyi ba tare da tuntubi likita ba.

1. Glibomet. Ya ƙunshi abubuwa masu aiki iri ɗaya: metformin da glibenclamide. Lokacin ɗaukar ƙwayar, ƙwayar hormones ta sel ƙwayar ƙwayar cuta tana haɓakawa kuma ƙwaƙƙwaran kyallen takarda zuwa aikin insulin yana ƙaruwa.

Amma Ba kamar Gluconorm ba, alamomi don amfani sun bambanta:

• Ana amfani da "Glibomet" lokacin da jiki ke tsayayya da abubuwan da suka samo asali na sulfonylurea saboda tsawaita amfani,
• tare da insulin-mai zaman kansa nau'in ciwon sukari.

Lokacin magani da yawan yau da kullun na Glibomet sun dogara ba kawai kan yawan glucose a cikin jini ba, har ma a kan yanayin haƙuri na ƙwayar carbohydrate.

Bambanci kuma yana bayyana kanta a wasu sakamakon illa:

• digo cikin farin jini,
• rashin lafiyan halayen bayyana kamar yadda fata halayen (itching, redness),
• An zaɓi ingantaccen sashi ne tare da sanya idanu akai-akai na haƙuri.

Kudin ya kai 90-100 rubles mafi girma.

Metglib. Abun da yake na asali yana kama da haka. Bambanci suna cikin haɓakar tsofaffi, waɗanda ke haifar da jinkiri ga ɗaukar glucose a cikin ƙananan hanji, da kuma hana gluconeogenesis da glycogenolysis a cikin hanta.

“Metglib” yana rage nauyin jikin mai haƙuri ta hanyar hana samuwar cholesterol da karancin lipoproteins mai yawa. An hana shi shan magani tare da Bozentan saboda haɗarin haɗarin hepatic.

Kudin bai kai na Gluconorm ba.

Magunguna da magunguna

Gluconorm ya ƙunshi madaidaiciyar haɗuwa na abubuwa biyu na hypoglycemic mallakar na rukuni na magunguna daban-daban: metforminda glibenclamide.

A lokaci guda, metformin wani yanki ne wanda ke da ikon rage girman glucose a cikin saitin kwayoyin jini. Ana samun wannan ta hanyar ƙara ƙarfin jijiyoyin kyallen na ƙasa zuwa aikin insulin da haɓaka kamawa glucose. Hakanan, sha daga carbohydrates daga narkewa yana narkewa kuma an hana shi gluconeogenesis a hanta. An lura da fa'idar amfani da magungunan, wanda ke nuna yanayin jijiyoyin jini, alamu na gaba ɗaya cholesterol datriglycerides. Hypoglycemic halayen ba su ci gaba.

Glibenclamide shine asalin ƙarni na biyu na tushen sulfonylurea. Wannan nau'in yana nunawa ta hanyar motsawar insulin ƙwaƙwalwa saboda raguwa a cikin tasirin fushi na sel β-glucose a cikin ƙwayar ƙwayar cuta, ƙwarewar insulin yana ƙaruwa, har ma da matsayin haɗinsa tare da ƙwayoyin manufa. Bugu da ƙari, ƙaddamar da insulin yana ƙaruwa, sakamakon insulin a cikin ɗaukar glucose ta kyallen tsoka kuma hanta yana ƙaruwa, kuma lipolysis a cikin kyallen takaddar abu an hana shi. Ayyukan wannan abu ya bayyana a mataki na 2 na sirri insulin

Magungunan suna da kyau daga ƙwayar narkewa. Ana samun mafi yawan maida hankali ne a cikin awanni 1.5. Sakamakon haka metabolism dayawa metabolites. An cire magungunan daga jikin mutum tare da taimakon kodan da hanjinsa.

Alamu don amfani

An wajabta aikace-aikacen Gluconorm nau'in ciwon sukari na 2 na manya marasa lafiya da:

• rashin ingancin maganin abinci, aikin motsa jiki da magani na baya tare da glibenclamide ko metformin,
• buƙatar maye gurbin ilimin da ya gabata tare da wannan magani ga marasa lafiya waɗanda ke da ingantaccen karatu da kuma sarrafawa cikin karatun jini.

Formaddamar da tsari da abun da ke ciki

Hanya sashi - allunan da aka shirya fim: zagaye, convex a garesu, kusan fari ko farar fata, a karaya - daga fari zuwa farin-launin toka mai launi (kwalaye 10 a cikin lamuni mai haske, 4 blisters a cikin kwali , Blister 2 a cikin kwali na kwali).

Abubuwa masu aiki a cikin kwamfutar hannu 1:

• metformin hydrochloride - 400 MG,
• glibenclamide - 2.5 MG.

Componentsarin abubuwan da aka haɗa: diethyl phthalate, sodium croscarmellose, glycerol, gelatin, sitaci masara, cellulosefate, talcic tsarkakakke, colloidal silicon dioxide, sodium carboxymethyl sitaci, microcrystalline cellulose, magnesium stearate.

Side effects

Lokacin shan Gluconorm, tasirin sakamako na iya haɓaka wanda ke shafar metabolism metabolism, hanta da aikin gastrointestinal, samuwar jini da tsarin juyayi. Wannan na iya kasancewa tare da: hypoglycemia, lactic acidosis, tashin zuciya, amai, ciwon ciki, rashi ci, leukopenia, thrombocytopenia, erythrocytopenia, ciwon kai, farin cikirauni, gajiya mai zafi da sauransu.

Gluconorm, umarnin don amfani (Hanyar da sashi)

Wannan magani an yi shi ne don maganin baka a lokaci guda kamar abinci. A wannan yanayin, an saita sashi na miyagun ƙwayoyi ta likita, yin la'akari da halayen kowane ɗayan mai haƙuri dangane da alamun nuna glucose na jini.

A matsayinka na mai mulki, magani yana farawa tare da tsarin yau da kullun - 1 kwamfutar hannu. Kowane mako 2, ana daidaita sashi gwargwadon matakin glucose a cikin jini. Lokacin da aka maye gurbin magani na baya tare da metformin da glybeklamide, ana ba allunan 1-2 ga marasa lafiya. A wannan yanayin, maganin yau da kullun ba zai iya zama sama da allunan 5 ba.

Alamu don alƙawarin gluconorm

A yawancin marasa lafiya da ke fama da cutar sankara, ƙwaƙwalwa guda ɗaya ba ta iya tsayar da glucose na al'ada, saboda haka yawancin likitoci sukan haɗa kai da magani. Nunin don alƙawarinsa akwai gemoclobin glycated sama da 6.5-7%.Mafi yawan la'akari da haɗuwa da haɗuwa da metformin tare da abubuwan da suka samo asali na sulfonylurea (PSM), gliptins da incetin mimetics. Duk waɗannan haɗuwa suna shawo kan juriya na insulin da ƙara yawan samar da insulin nan da nan, saboda haka suna ba da sakamako mafi kyau.

Haɗin metformin + sulfonylurea shine mafi yawan gama gari. Abubuwa basa iya hulɗa da junan ku, kada ku rage tasiri. Glibenclamide shine mafi iko da kuma nazarin dukkan PSM. Yana da ƙananan farashi kuma ana siyar dashi a cikin kowane kantin magani, sabili da haka, a hade tare da metformin, an tsara glibenclamide fiye da sauran kwayoyi. Don sauƙaƙan amfani, an ƙirƙiri allunan abubuwa guda biyu tare da waɗannan sinadaran biyu masu aiki - Gluconorm da analogues.

Dangane da umarnin, ana amfani da Gluconorm na musamman ga masu ciwon sukari na 2, idan gyaran abinci, wasanni, da metformin ba su haifar da digo a cikin glucose don ƙima ƙima. Yawan maganin metformin ba zai zama mafi ƙarancin inganci ba (2000 mg) ko kuma mai ciwon sukari ya jure da shi. Hakanan, ana iya ɗaukar gluconorm ta hanyar marasa lafiyar da suka sha glibenclamide a baya kuma metformin daban.

An gano bincike: ƙarancin allunan da mai haƙuri ke ɗauka kowace rana, da ƙari yana da sha'awar bin duk abubuwan da likita ya bayar, wanda ke nufin cewa mafi girman tasirin magani. Wato, shan Gluconorm maimakon allunan guda biyu ƙaramin mataki ne don mafi kyawun diyya ga masu ciwon sukari.

Bugu da kari, haɓaka sau biyu a cikin matakan allunan sukari masu rage sukari baya bayar da raguwa iri ɗaya cikin sukari. Wato, kwayoyi guda biyu a cikin ƙaramin aiki zasu yi aiki sosai kuma suna ba da ƙananan sakamako fiye da ɗaya magani a cikin iyakar adadin.

Abun da kuma maganin yake dashi

Gluconorm an samar da kamfanin nan na Rasha tare da Pharmstandard tare da haɗin gwiwar Indian Biopharm na Indiya. Ana amfani da miyagun ƙwayoyi a cikin sigogi 2:

1. Ana yin allunan gluconorm a Indiya, an shirya su a Rasha. Magungunan suna da maganin gargajiya na 2.5-400, wato, kowane kwamfutar hannu na metformin ya ƙunshi 400 mg, glibenclamide 2.5 MG.
2. Ana samar da allunan gluconorm Plus a cikin Russia daga kayan magani wanda aka saya a Indiya da China. Suna da sashi guda 2: 2.5-500 ga masu ciwon sukari tare da juriya ta insulin da 5-500 ga marasa lafiya ba tare da wuce kima ba, amma tare da nuna karancin insulin.

Godiya ga zaɓuɓɓukan sashi daban-daban, zaku iya zaɓar madaidaiciyar rabo ga kowane mai haƙuri da ciwon sukari na 2.

Bari muyi la’akari dalla-dalla yadda abubuwan da ke cikin magungunan Gluconorm ke aiki. Metformin yana rage duka postprandial da azumi glycemia wanda yafi yawa saboda raguwar juriya na insulin. Glucose yana barin tasoshin da sauri, saboda jijiyoyin nama zuwa insulin yana ƙaruwa. Metformin shima yana rage samuwar glucose a jiki daga abubuwanda basa amfani da shi, yana rage jinkirin shiga cikin jini daga narkewar abinci.

Ga masu ciwon sukari, ƙarin kaddarorin metformin waɗanda basu da alaƙa da raguwa a cikin glycemia suma suna da matukar muhimmanci. Magani ya hana haɓakar angiopathy ta hanyar inganta lipids na jini, yana inganta abinci mai gina jiki. A cewar wasu rahotanni, metformin yana iya hana bayyanar neoplasms. A cewar masu haƙuri, yana rage yawan ci, yana taimakawa ci gaba da nauyin al'ada, yana ƙarfafa nauyi, da ƙara haɓaka abincin.

Glibenclamide shine PSM 2 tsara. Yana aiki kai tsaye akan sel na fitsari: yana rage ƙarshen ƙimar hankalinsu ga matakan glucose na jini, ta haka ne zai ƙara samar da insulin. Har ila yau, Glibenclamide yana haɓaka glycogenogenesis - tsari na adana glucose a cikin tsokoki da hanta. Ba kamar metformin ba, wannan magani na iya haifar da hypoglycemia, mafi tsananin ƙarfi fiye da sauran wakilan ƙungiyar PSM - glimepiride da glyclazide. Ana daukar Glibenclamide mafi ƙarfi, amma kuma mafi hatsarin PSM. Ba'a ba da shawarar ga masu ciwon sukari ba tare da haɗarin hypoglycemia.

Yadda ake shan Maganin Gluconorm

Mafi yawan tasirin sakamako na metformin shine narkewa, glibenclamide - hypoglycemia. Kuna iya rage haɗarin mummunan sakamako na jiyya tare da gluconorm, shan kwayoyi a lokaci guda kamar abinci kuma sannu a hankali suna kara kashi, fara da mafi ƙarancin.

Sashi na miyagun ƙwayoyi Gluconorm bisa ga umarnin:

Tare da juriya na insulin mai ƙarfi, wanda shine halayen mutane masu kiba da ciwon sukari, ana iya tsara ƙarin metformin. Yawancin lokaci a wannan yanayin suna shan shi kafin zuwa gado. Mafi kyawun kashi na yau da kullun metformin ana ɗauka shine 2000 MG, matsakaicin - 3000 MG. Furtherarin ƙaruwa a sashi yana da haɗari tare da lactic acidosis.

Tare da rashin carbohydrates a cikin abinci, Gluconorm yana haifar da hypoglycemia. Don hana shi, allunan sun bugu tare da manyan abinci. Dole ne samfura su ƙunshi carbohydrates, mafi yawan jinkirin. Ba za ku iya ba da damar dogon tsayi tsakanin abinci ba, saboda haka ana ba da shawarar ƙarin haƙuri. Binciken masu ciwon sukari sun nuna cewa tare da matsanancin ƙoƙarin jiki, sukari na iya faɗuwa cikin 'yan mintina. A wannan lokacin, kuna buƙatar ku mai da hankali musamman ga lafiyar ku.

Analogs da wasu abubuwa

Cikakken analogues, kazalika da metformin da glibenclamide daban, zasu iya zama masu maye cikin kwanciyar hankali iri daya kamar na Gluconorm. Idan kuna shirin canzawa zuwa jiyya tare da wani tsararren maganin sulfonylurea, Dole ne a sake zaɓin kashi. Likitocin sun ba da shawarar sauya sheka daga Gluconorm zuwa Amaryl ko Glimecomb ga masu ciwon sukari masu fama da cututtukan carbohydrate na 2, wanda yawanci ke fama da cutar sikari.

Dangane da sake dubawa, tasiri na Gluconorm da analogues yana kusa, amma masu ciwon sukari sun fi son Glybomet na Jamusanci, suna la'akari da shi a matsayin magani mafi inganci.

Dokokin ajiya da farashi

Gluconorm yana da tasiri har tsawon shekaru 3 daga ranar samarwa. An ba da izinin Gluconorm Plus don adanawa sama da shekaru 2. Koyarwar ba ta ƙunshi buƙatu na musamman don yanayin ajiya, ya isa a lura da tsarin yanayin zafi wanda bai wuce digiri 25 ba.

Masu ciwon sukari na Rasha na iya karɓar magunguna biyu gwargwadon rubutaccen magani da babban likitan likitanci ko kuma endocrinologist ya tsara. Sayayyar mai zaman kanta zata kashe mara tsada: farashin fakitin 40 allunan Gluconorm kusan 230 rubles ne, Gluconorm Plus farashin daga 155 zuwa 215 rubles. na allunan 30. Don kwatantawa, farashin asalin Glibomet shine kusan 320 rubles.

Tabbatar koya! Shin kuna tsammanin kulawa da kwayoyin hana daukar ciki da insulin shine hanya daya tilo da za'a kula da sukari? Ba gaskiya bane! Kuna iya tabbatar da wannan da kanku ta hanyar fara amfani da shi. kara karantawa >>

Siffofin aikace-aikace

Wajibi ne a soke magani tare da magani don cututtukan cututtuka tare da zazzabi, tare da raunin da ya faru da kuma maganin tiyata. Rashin haɗarin rage yawan sukari a lokacin yunwar, amfani da NSAIDs, ethanol yana ƙaruwa. Ana yin gyaran sashi ne lokacin da ake canza abinci, mai karfi na ɗabi'a da ƙoshin lafiya.

Umarnin Gluconorm ya ba da shawarar cewa ba da shawarar shan giya a lokacin da ake warkarwa. Kwayoyi na iya shafar saurin halayen psychomotor kuma rage taro. Sabili da haka, dole ne ku mai da hankali yayin tuki da haɗari.

Haramun ne a sha kwaya a yara, a lokacin daukar ciki, yayin shayarwa, saboda manyan abubuwanda ke shigar da madarar uwar. Magungunan yana contraindicated a cikin mutane tare da pathologies na kodan da hanta. Ba'a bada shawarar amfani da allunan a cikin tsofaffi a hade tare da matsanancin ƙoƙari na jiki ba.

Yin hulɗa tare da wasu kwayoyi

Kafin farawa da jiyya, kuna buƙatar koya game da yadda Gluconorm ke hulɗa tare da sauran magunguna:

• haɓaka kayan ƙawancen hypoglycemic: ACE inhibitors, MAO, NSAIDs, fibrates, allopurinol, steroids anabolic, magungunan rigakafin tarin fuka, allunan acidcing na fitsari,
• raunana sakamako: hana haihuwa, magungunan aidin dake dauke da sinadarin thyroid, barbiturates, adrenostimulants, corticosteroids, yawan sinadarin nicotinic acid, glucagon, furosemide, thiazide diuretics, magungunan antiepileptic,
• kara matakan metformin: magungunan cationic, furosemide,
• levelsarin matakan furosemide: metformin,
• jinkirin kawar da metformin: nifedipine.

Sashi da gudanarwa

Ana nuna gluconorm don amfani da baka. Allunan ya kamata a ɗauka tare da abinci.

An zaɓi cikakken isasshen magani ga kowane mai haƙuri daban-daban dangane da bayanai kan matakin glucose a cikin jini.

Maganin farko shine yawanci 1 kwamfutar hannu sau 1 a rana. Idan ya cancanta, ƙara kashi a kowane mako 1-2 har sai an sami sakamako da ake so.

Idan an tsara Gluconorm, maimakon haɗuwa da kwayoyi biyu - metformin da glibenclamide - an ƙaddara adadin gwargwadon abubuwan da suka gabata na kowane sashi, yawanci ana ba allunan 1-2.

Matsakaicin izini na izini shine 5 Allunan a rana.

Bayani na gaba daya, abun da ya shafi da kuma sakin saki

Gluconorm wani nau'in ƙwayoyin cuta ne wanda aka kera a Indiya. Baya ga tasirin sukari, maganin yana taimakawa rage girman kwayar cholesterol a cikin jinin mai haƙuri.

An ba da izinin rarraba kuɗi gwargwadon takardar sayen halartar ƙwararrun halartar. Ana amfani da maganin har tsawon shekaru 3 daga ranar da aka ƙera shi.

Wajibi ne a lura da yanayin ajiya na wannan magani. An adana shi a cikin duhu ba tare da samun damar yara ba. Matsakaicin yanayin ajiya shine 20-23 0 C.

Bugu da ƙari, Gluconorm tare da ruwan hoda na shuɗi a cikin shayi na ganye, an samar da shi, wanda ba magani bane, amma ana ɗaukar shi azaman rage yawan sukari.

Daga cikin sauran abubuwan haɗin maganin, an lura da sodium carboxymethyl sitaci, magnesium stearate da cellacephate. A wasu takamaiman, talc tare da sitaci na masara da gelatin yana cikin halayen magunguna.

Packaya daga cikin fakitin Allunan yana dauke da blister 1-4. A cikin blister na iya zama allunan 10, 20, 30 na maganin. Allunan maganin suna da fari kuma suna da sifar zagaye na biconvex. A lokacin hutu, allunan zasu iya samun dan kadan mai launin toka.

Gluconorm blueberry tea bai ƙunshi abubuwan da ake gabatar dasu a allunan ba. An yi shi ne daga ganyayyaki na halitta kuma ana sayar dashi a cikin nau'ikan jaka na shayi. An tsara hanya don 3 makonni.

Pharmacology da kuma kantin magunguna

Gluconorm ya ƙunshi manyan abubuwan biyu: Glibenclamide da Metformin. Duk abubuwan guda biyu suna aiki a cikin haɗin haɗin gwiwa, yana haɓaka tasiri na miyagun ƙwayoyi.

Glibenclamide shine asalin ƙarni na biyu na tushen sulfonylurea. Sakamakon aikinsa, ƙwayar insulin yana motsawa, kuma yana haifar da rashin lafiyar insulin a cikin ƙwaƙwalwar ƙwayar cuta.

Glibenclamide yana haɓaka aikin fito da insulin kuma yana haɓaka tasirinsa akan sha na glucose ta hanta, da ma tsokoki. A karkashin aikin wani abu, aiwatar da rarrabuwar kitse a cikin tsose kyallen takarda yayi saurin sauka.

Metformin abu ne na biguanide. Sakamakon aikinsa, yana rage yawan glucose a cikin jinin mara lafiya, akwai karuwar karuwar glucose da ƙwararren yanki.

Abun yana dacewa da raguwa a cikin ƙwayar cholesterol a cikin jini. Sakamakon ayyukan Metformin, yawan shan carbohydrates a cikin ciki da hanji yana raguwa. Abinda yake a hankali yana hana samuwar glucose a cikin hanta.

Glibenclamide da Metformin, waɗanda suke ɓangare na miyagun ƙwayoyi, suna da magunguna daban-daban.

Yawan sha daga glibenclamide bayan shigowa daga ciki da hanjinsa ya kai kashi 84%. Matsakaicin maida hankali na kashi ana iya isa shi cikin awa daya ko biyu. Abubuwan suna da alaƙa da sunadarai na jini. Adadin shine kashi 95%. Mafi karancin rabin rayuwa shine 3 hours, matsakaicin shine 16 hours. Kodan ya rabu da sashin jikinta, wani ɓangare kuma hanjinsa ya rabu dashi.

Matsakaicin bioavailability na Metformin bai wuce 60% ba. Cin abinci yana rage jinkirin rage sinadarin metformin. Duk wani abu da aka ɗauka akan komai a ciki yana narkewa daga ciki da hanjinsa.

Ba kamar Glibenclamide ba, yana da ƙananan haɗin gwiwa tare da sunadarai na jini. Kodan ya fice. 30% na abu na iya kasancewa a cikin yanayin mai haƙuri. Cire rabin rayuwa ya kai awa goma sha biyu.

Manuniya da contraindications

Babban nuni ga shan wannan magani shine kasancewar nau'in ciwon sukari na II a cikin haƙuri. Hakanan, an wajabta magungunan a cikin rashin tasirin sakamako na dacewa tare da abinci, motsa jiki da kuma aikin kwantar da hankali dangane da shan Metformin tare da Glibenclamide.

Hakanan ana nuna magungunan ga marasa lafiya waɗanda ke da sukari na yau da kullun masu daidaituwa, amma waɗanda ke da buƙatar maye gurbin jiyya tare da Glibenclamide da Metformin.

Babban adadin contraindications halaye ne na magani:

• gazawar hanta
• low sugar sugar (hypoglycemia),
• babban hankali ga abubuwan da ke cikin miyagun ƙwayoyi,
• nau'in ciwon sukari
• na kullum,
• ciki
• aikin lalacewa na aiki sakamakon kamuwa da cuta, amai,
• ketoacidosis
• amfani da miconazole,
• gaban konewa a jiki,
• bugun zuciya
• nono
• cututtuka daban-daban
• masu fama da cutar sankara
• na gazawar
• infarction na zuciya
• m shisshigi
• lactic acidosis,
• barasa mai guba
• gazawar numfashi
• maganin ciwon sukari
• cutar porphyrin.

Marasa lafiya na musamman da kuma Jagorori

An haramta wannan maganin ga mata masu juna biyu. Hakanan ba za a yarda a sha maganin ba yayin shirin daukar ciki.

Bai kamata a shawo kan ƙwayar cuta ta hanyar lactate mata ba, tunda Metformin yana ratsa jiki cikin madara kuma yana iya cutar lafiyar jariri. A cikin waɗannan halayen, ana bada shawarar maye gurbin magani tare da maganin insulin.

Ba'a ba da shawarar maganin ba ga tsofaffi marasa lafiya waɗanda shekarunsu ya wuce 60. Haɗe tare da manyan lodi, Gluconorm na iya haifar da lactic acidosis a cikin wannan rukuni na mutane.

Magungunan yana buƙatar kulawa da hankali ta hanyar marasa lafiya da ke fama da:

• kasawar kasa,
• zazzabi
• cututtukan thyroid.

Don magani, ana ba da umarnin musamman da yawa:

• yayin lura, kulawa akai-akai na matakan glucose na jini ya zama dole duka a kan komai a ciki kuma bayan cin abinci,
• hadin gwiwa magani da barasa an haramta,
• yana da mahimmanci don maye gurbin maganin tare da maganin insulin idan mai haƙuri yana da raunin, cututtuka, zazzabi, ƙonewa, ayyukan da suka gabata,
• Kwanaki 2 kafin gabatarwar wani abu mai dauke da kayan maye wanda yake dauke da aidin a jikin mai haƙuri, ya zama dole a daina shan maganin (bayan kwana 2, an sake dawo da abincin),
• haɗin gwiwa na Gluconorm tare da ethanol suna tsokani cutar rashin ƙarfi, hakan kuma yana faruwa yayin azumi da shan magungunan anti-mai kumburi da nau'in steroid,
• miyagun ƙwayoyi suna shafar ikon mai haƙuri na fitar da mota (dole ne ku guji tafiya da mota yayin magani tare da miyagun ƙwayoyi).

Ra'ayoyin masu haƙuri

Yawancin sake dubawa game da masu ciwon sukari game da miyagun ƙwayoyi Gluconorm sun ƙunshi mafi kyawun amsawa ga shan magungunan, duk da haka, an ambaci sakamako masu illa, daga cikinsu akwai tashin zuciya da ciwon kai wanda galibi ake fuskanta, wanda ake kawar da shi ta hanyar daidaitawa ta kashi.

Magungunan suna da kyau, yana rage sukari da kyau. Abin mamaki, ban sami sakamako masu illa ba waɗanda yawanci ana rubuta su ne game da. Farashin mai araha. Ina yin oda Gluconorm akan tsarin cigaba.

Na kasance ina fama da ciwon sukari irin na 2 shekaru da yawa. The halartar likita wajabta Gluconorm. Da farko, akwai sakamako masu illa: sau da yawa ba shi da lafiya, akwai rashin jin daɗi. Amma a nan gaba mun daidaita kashi, kuma komai ya wuce. Kayan aiki yana da tasiri idan kun hada abubuwan ci da abinci.

Gluconorm ya dogara gaba daya. A halin da nake ciki, Na taimaka don kara daidaita nauyi. Magungunan yana rage yawan ci. Daga cikin minuses, zan bayyana sakamako masu illa. Da yawa daga cikinsu. A wani lokaci, kai na ba shi da lafiya.

Ba haka ba da daɗewa ba, masanin ilimin endocrinologist yayi wani mummunan bincike - mai ciwon sukari na 2. An wajabta gluconorm don gyara sukarin jini. Gaba ɗaya farin ciki tare da jiyya. Tare da sukari mai yawa, ƙwayar za ta iya rage matakin zuwa 6 mmol / L. Akwai wasu sakamako masu illa, amma an cire su. Ana buƙatar rage cin abinci.

Farashin gluconorm a yankuna daban-daban na kasar yana da bambance-bambance. Matsakaicin farashin ƙasar shine 212 rubles. Matsakaicin farashin magungunan shine 130-294 rubles.