Menene mafi kyawun phasostabil ko cardiomagnyl?

Hanyar aiki na acetylsalicylic acid (ASA) ya dogara ne akan hanawar cyclooxygenase (COX-1), sakamakon abin da aka toshe kwayar cutar thromboxane A2 kuma an dakatar da tarawar platelet. An yi imanin cewa ASA tana da wasu hanyoyin da za su iya magance haɗarin platelet, wanda ke faɗaɗa girman ta a cikin cututtukan jijiyoyin jiki daban-daban. Hakanan ASA yana da anti-inflammatory, analgesic, antipyretic sakamako. Tasirin anti-mai kumburi yana hade da raguwar kwararar jini saboda hanawar sinadarin prostaglandin E2. Magnesium hydroxide, wanda yake wani ɓangare ne na miyagun ƙwayoyi Fazostabil, yana da tasirin antacid kuma yana kare ƙwayoyin mucous na ƙwayar gastrointestinal daga tasirin ASA.

Alamu don amfani

- rigakafin farko na cututtukan zuciya kamar su fitsari da kuma kasala na zuciya a gaban abubuwanda ke haifar da hadari (misali cutar sankara, mellitus, ciwon hawan jini, hauhawar jini, kiba, shan taba, tsufa). - Yin rigakafin yaduwar cututtukan zuciya da kuma jijiyoyin jini. - Yin rigakafin thromboembolism bayan tiyata na jijiyoyin jini (jijiyoyin zuciya jijiyoyin bugun jini, percutaneous transluminal na jijiya angioplasty). - Rashin tsayayyen angina

Contraindications

- Hypersensitivity ga ASA, excipients da sauran magungunan anti-mai kumburi mai guba (NSAIDs), - Ciwon jini, - Zinawar jini (karancin Vitamin K, thrombocytopenia, basur mai narkewar cuta), - Class III-IV na rashin lafiyar zuciya a cewar rarrabuwa NYHA, - Ciwon asma da ke faruwa ta hanyar salicylates da NSAIDs, - Cikakken ko ba a kammala ba game da tarin asma, maimaituwar hanci da maimaituwar ƙwayar cuta, da kuma haƙurin rashin haƙuri. da ASA ko wasu NSAIDs, ciki har da cyclooxygenase-2 inhibitors (COX-2) (ciki har da tarihi), - Erosive-ulcerative raunuka na gastrointestinal fili (a cikin matsanancin lokaci), - Gastrointestinal na jini, - Ciwon koda na koda ( sharewar creatinine (CC kasa da 30 ml / min.), - Rashin hanta (Rashin Cutar yara-B da C), - Cutar ciki (I and III trimesters), lokacin shayarwa, - Glucose-6-phosphate dehydrogenase karancin, - Gudanar da lokaci ɗaya tare da methotrexate (fiye da 15 MG a mako), - Yara underan ƙasa da shekaru 18.

Sashi da gudanarwa

A ciki, allunan da ke rufe fim na miyagun ƙwayoyi Fazostabil an hadiye su duka, an wanke su da ruwa. Phazostabil an yi niyya don magani na dogon lokaci. Tsawon likitan yana ƙaddara tsawon lokacin jiyya. - rigakafin farko na cututtukan zuciya kamar su thrombosis da matsanancin rauni na zuciya a gaban abubuwan haɗari (alal misali, ciwon sukari mellitus, hyperlipidemia, hauhawar jini, kiba, shan sigari, tsufa) 1 kwamfutar hannu na ƙwayar cuta ta Phasostabil mai dauke da ASA a cikin kashi 150 MG a farkon rana, to 1 kwamfutar hannu 1 dauke da ASA a cikin kashi 75 mg 1 lokaci a rana. - Yin rigakafin raunin myocardial na dawowa da saukar jini guda 1 na kwayar cuta ta Phasostabil dauke da kwayar cutar ASA a cikin kashi 75-150 mg sau daya a rana. - Yin rigakafin thromboembolism bayan tiyata na jijiyoyin jini (jijiyoyin zuciya jijiya grafting, percutaneous transluminal na jijiya angioplasty) 1 kwamfutar hannu na magani Phasostabil dauke da ASA a cikin kashi 75 - 150 MG sau ɗaya a rana. - stwaƙwalwar ƙwayar angina pectoris 1 mai ƙwaƙwalwar ƙwayar cuta ta Phasostabil mai dauke da ASA a cikin kashi 75-150 MG sau ɗaya a rana. Lokacin yin tsallake kashi na gaba na miyagun ƙwayoyi, Phazostabil, yana da mahimmanci don ɗaukar kashi da aka rasa na maganin da zaran mai haƙuri ya tuna da wannan. Don gujewa ninkawa kashi, bai kamata ku ɗauki kwamfutar da aka rasa ba idan lokacin shan magani na gaba yana gabatowa. Ba'a lura da alamun daidaituwa na aiki yayin gudanarwa na farko ko kuma dakatar da miyagun ƙwayoyi ba.

Fom ɗin saki

Allunan-fim ɗin da aka rufe 75 MG + 15.2 mg da 150 MG + 30.39 mg. A kan allunan 10, 20, 25 ko 30 a cikin marfin murfin buroshi daga fim na polyvinyl chloride da allon allon almara na almara. Gilashin daya ko 1, 2, 3, 4, 5, 6, 7, 8, 9 ko 10 blister strip packings, tare da umarnin amfani, an sanya su a cikin kwali mai kwali (fakitin).

Bayanin kwatancen kwayoyi

Phasostabil - sanannen wakilin antiplatelet, ana samarwa a cikin Rasha ta kamfanin Ozone. Ana samun allunan a cikin murfin fim, wanda ke rage haɗarin lalacewar gastrointestinal. Allunan sun kasance oval, fari tare da marbling, biconvex, sanye take da layin rabawa. Farashin don allunan 50 shine 218 rubles.

Yawan maganin shine 150 + 30.39 MG, kazalika da 75 + 15.2 mg.

A matsayin ɓangare na miyagun ƙwayoyi - acetylsalicylic acid (ASA) a cikin adadin 150 ko 75 MG, an dauke shi babban bangaren aiki. Don haɓaka tasirin warkewa, an gabatar da magnesium hydroxide a cikin abun da ke ciki - 30.39 ko 15.2 mg.

Lokacin sayen magunguna don tsarke jini, marasa lafiya suna sha'awar abin da ya fi kyau - Phasostabil ko Cardiomagnyl? Dangane da alamu da abun da ke ciki, Cardiomagnyl bai bambanta da Phasostabil ba. Ya ƙunshi adadin magnesium hydroxide da acetylsalicylic acid, waɗanda aka samar da irin wannan sikari. Farashin maganin yana daga 170 zuwa 300 rubles a allunan 100, sabili da haka, babu bambance-bambance a cikin kudin ko dai. Takeda ya kera magungunan.

Substancesarin abubuwa na allunan nau'ikan biyu:

• cellulose
• magnesium stearate,
• macrogol
• maganin.

Akwai ɗan bambanci a cikin abubuwan haɗin sauran kayan taimako. Don haka, a cikin Cardiomagnyl akwai povidone, titanium dioxide, sodium croscarmellose. A cikin Phasostabilum, sitaci na masara da dankalin turawa, talc suna nan. Wani magani yana iya zama mafi kyau kawai ga waɗanda suke rashin lafiyar waɗannan abubuwan, in ba haka ba magungunan suna da cikakkiyar musanyawa.

Aiwatar da kwayoyi

Haɗin ya haɗa da ASA, wanda ke nufin magungunan rigakafin rashin kumburi. Wannan abu yana aiki bisa ga tsari mai zuwa - yana hana sakin enzyme COX-1, wanda ke haifar da katange samar da thromboxane A2. A sakamakon haka, wannan yana haifar da raguwa a cikin hanyoyin gluing. ASA yana aiki da wasu hanyoyin da ba a fahimta sosai ba, amma suna haifar da sakamako iri ɗaya. Daga cikin wadansu abubuwa, kayan sunada wadannan ayyukan:

Baya ga ASA, magnesium yana nan a cikin nau'in hydroxide. An yi nufin kare mucosa na ciki daga lalacewa ta hanyar acetylsalicylic acid. Magnesium hydroxide nasa ne na antacids, yana rufe jikin mucous membrane kuma yana hana tsarin kumburi. Magungunan suna da cikakkiyar sha da kuma wadatuwa mai yawa, amma idan kun sha shi tare da abinci, ingancin ya ragu. A cikin mata, aiki da kawar da ASA ya kasance mai sauƙi, kamar yadda yake tare da cututtukan hanta da koda.

Alamu na Phasostabil da Cardiomagnyl

Ya kamata a sha magunguna tare da yawan cututtukan zuciya. Mafi sau da yawa, alƙawarin Cardiomagnyl da kwatankwacinsa ana danganta shi da rigakafin ƙwayoyin thrombosis da thromboembolism a gaban abubuwan haɗari a cikin haƙuri:

• tsufa
• shan taba sigari
• ciwon sukari mellitus
• kiba

Don hana ƙirƙirar ƙwayar cuta, da kuma hana ci gaban zuciya, an wajabta kuɗi a cikin hadadden lura da atherosclerosis da hauhawar jini. Tare da bugun zuciya, Cardiomagnyl shine mafi yawan lokuta ana ba da shawarar don gudanarwa na tsawon rai don rigakafin sake faruwa. Hakanan ana nuna magunguna don cututtukan jijiyoyin zuciya tare da angina pectoris na al'ada ko ba su da matsala.

Bayan tiyata a kan tasoshin zuciya (angioplasty, kewaye tiyata), magungunan ba za su ba da izinin thromboembolism ba.

Contraindication sun hada da rashin haƙuri, rashin lafiyan ga acetylsalicylic acid, da sauran abubuwan da aka gyara. Haramun ne haramcin a bi da shi tare da magani don maganin basur, ƙarancin darajar ƙarancin Vitamin K, tare da thrombocytopenia da basur na basur. Yanayin aiki na iya haifar da zubar jini ba tare da kulawa ba. Wasu abubuwan da aka haramta:

• 1.3 watanni na lokacin haihuwa,
• shekaru zuwa shekaru 18
• yashwa, ciwon mara mai nauyi,
• mai rauni na koda

A karkashin kulawa na likita, suna shan kwayoyi tare da tarihin cututtukan gastritis da ciwan ciki, tare da gout, asthmaal asthma, hanci na polyposis, a cikin karo na 2 na mata masu ciki.

Umarnin don amfani

Ana ɗaukar magunguna daidai wannan hanya, babu bambanci tsakanin umarnin far. Dukkan su biyun an yi niyya don kwasa-kwasan dogon lokaci, amma likitan likitan ya ƙayyade daidai da yanayin haƙuri. Sha kwayoyin hana ruwa da ruwa. Sau da yawa, Panangin, Asparkam, da sauran magungunan zuciya ana rubuta su tare da su.

Idan ya cancanta, za'a iya raba kwamfutar hannu a hadarin.

Ana yin farashi da safe, sa'a daya bayan cin abinci. Ana ba da shawarar kullun cewa ku sha Phasostabil ko Cardiomagnyl sau ɗaya / rana. Anan ne hanyoyin samun allurai:

rigakafin thrombosis, matsanancin rauni na zuciya - 150 g a ranar farko, sannan 75 MG na tsawon tsayi (kashi ga mutanen da ke da haɗari),

Idan mara lafiya ya rasa liyafar, zaku iya shan kwaya a kowane lokaci, koda da yamma. Idan lokaci na gab da na gaba na gaba, an sakin kashi, ana sake ninka yawan ba tare da izini ba. An haramta yin amfani da yawan ruwa sosai, musamman a cikin tsofaffi marasa lafiya. Babban guba yana tasowa lokacin cinyewa sama da 100 MG / kilogiram na ƙwayar jiki. Jiyya kawai a asibiti!

Menene mafi kyawun atacecardol ko Cardiomagnyl?

Acekardol da Cardiomagnyl sune analogues wadanda suke da tasirin irinsu a jiki. Bambanci tsakanin magungunan ba mahimmanci bane, kuma umarnin yin amfani dasu iri daya ne. Siffofin kowane magani da manyan bambance-bambance tsakanin su:

1. Kasar ta asali. Acekardol magani ne na Rasha, kuma ana samar da Cardiomagnyl a Jamus.
2. Farashin magani. Ankara ana samar da shi a Rasha sau da yawa ya fi rahusa fiye da na waje.
3. Tsarin kwamfutar hannu. Magungunan Jamusanci an saki su a cikin nau'ikan zukata, kazalika a cikin nau'i na ellipsoids tare da daraja a tsakiya. Kamfanin masana'antar Rasha yana samar da daidaitattun allunan alluna.
4. Sashi na aiki abu (asfirin). Kwamfutar hannu guda ɗaya ta ƙunshi 75 MG na kayan aiki mai aiki, kwamfutar hannu mai motsi ta ƙunshi 150 MG. Analog na Rasha ya ƙunshi 50, 100 da 300 na asfirin.
5. Abun da magani. Yawancin masu amfani da makamashin sun yi imanin cewa Cardiomagnyl ya fi Acecardol, saboda ya ƙunshi magnesium hydroxide, wanda ke kare ƙwayoyin gastrointestinal daga mummunan tasirin.

Tsekardol - ɗayan analogues, shima yana da anti-mai kumburi da kuma sakamakon bakin jini. Koyaya, zai fi kyau a nemi likitan zuciyar don zaɓin maganin da ya dace.

Analogs da sakamako masu illa

Analog mai rahusa shine magani na Trombital (farashin don 100 Allunan - 230 rubles). Za'a iya zaɓar sauran hanyoyin daga jeri, duk suna da matakan nuna rashin yarda. Yawancinsu basu da kayan kariya, wanda yakamata ayi la'akari dashi yayin jiyya:

Daga cikin sakamako masu illa, ana samun halayen rashin lafiyan wasu lokuta, wani lokacin har suka kai ga matsayin mai tsauni, har zuwa cutar anafilais. Mafi sau da yawa, urticaria, fitsari, jan fata fata yana tasowa. Daga cikin jijiyoyin ciki, tashin zuciya, ƙwannafi, jin zafi a ciki da ciki na iya faruwa. A cikin manyan maganganu, cututtukan ciki, fashewar cututtukan gastritis na faruwa. Wani lokaci, zubar jini daga cikin gastrointestinal fili, lalacewa ta esophagus, esophagitis ana yin rikodin. Tare da shigarwar lokaci mai tsawo, an lura da tsauraran matakan esophageal a cikin yawancin marasa lafiya. Sau da yawa, ciwo na hanji yana tasowa.

Sunan kasa da kasa mai zaman kansa

INN na wannan magani shine Acetylsalicylic acid + Magnesium hydroxide.

A cikin rarrabawa na duniya na ATX, magani yana da lambar B01AC30.

Ana amfani da miyagun ƙwayoyi a cikin nau'i na allunan mai rufi tare da rufin kariya na fim.

Saki siffofin da abun da ke ciki

Ana amfani da miyagun ƙwayoyi a cikin nau'i na allunan mai rufi tare da rufin kariya na fim. Yawan sashi na allunan shine 75 MG da 150 MG. Babban sinadaran aiki na maganin shine acetylsalicylic acid a cikin kashi 75 ko 150 MG da magnesium hydroxide a cikin adadin 15 ko 30 MG. Daga cikin wadansu abubuwa, abun da ke tattare da miyagun ƙwayoyi ya haɗa da irin waɗannan abubuwan taimako kamar sitaci, talc, hypromellose, magnesium stearate, macrogol da cellulose.

Allunan 75m suna cikin sifar zuciya. Magunguna tare da sashi na 150 MG yana da siffar m. Allunan suna cikin akwatunan filastik guda 10. An saka blisters a cikin kwali na kwali, wanda yake a ciki an rufe umarnin.

Pharmacokinetics

Abubuwan da ke aiki na Phasostabil suna kusan kasancewa cikin jikin ganuwar ƙwayar gastrointestinal. Tare da halartar enzymes na hanta, abu mai aiki yana canzawa zuwa salicylic acid. Matsakaicin ƙwayar ƙwayar plasma na abubuwanda ke aiki da metabolites dinsu ya kai bayan kimanin sa'o'i 1.5. Abubuwan da ke aiki da magunguna suna daure gaba daya zuwa garkuwar plasma. Abubuwan fashewar magungunan an cire su daga jiki a cikin kwanaki 2.

Abubuwan da ke aiki na Phasostabil suna kusan kasancewa cikin jikin ganuwar ƙwayar gastrointestinal.

Menene taimaka?

Amfani da phasostabil yana nunawa a cikin tsarin rigakafin cututtukan zuciya da jijiyoyin jini, gami da bugun zuciya. Sau da yawa, ana sanya wannan maganin a cikin allurai don kiyayewa ga mutanen da ke cikin haɗari don haɓakar cututtukan zuciya, ciki har da marasa lafiya da ke fama da ciwon sukari, yawan kiba, hauhawar jini. Za'a iya yin amfani da kayan aiki don jinin bakin ciki a matsayin wani ɓangare na rigakafin infarction na maimaita katako ko m thrombosis.

Daga cikin wadansu abubuwa, ana iya amfani da wannan magani don maganin thromboembolism na tsokoki. Ana ba da wannan magani sau da yawa a cikin lura da m angina pectoris. Bugu da kari, ana iya amfani da miyagun ƙwayoyi a matsayin wani ɓangare na rigakafin thrombosis bayan tiyata na jijiyoyin jini.

Tare da kulawa

Yin amfani da phasostabil a cikin lura da marasa lafiya da hyperuricemia ko gout yana buƙatar taka tsantsan. Bugu da kari, ana buƙatar kulawa ta musamman ta likitoci lokacin amfani da wannan magani a cikin lura da marasa lafiya waɗanda ke da tarihin zubar jini.

Amfani da phasostabil yana nunawa a cikin tsarin rigakafin cututtukan zuciya da jijiyoyin jini, gami da bugun zuciya.
Sau da yawa ana sanya wannan magani ga mutanen da ke fama da ciwon sukari.
Sau da yawa, ana sanya wannan maganin don masu kiba.
Ana iya amfani da maganin a matsayin wani ɓangare na rigakafin thrombosis bayan tiyata na jijiyoyin jini.

Gastrointestinal fili

A wani bangare na tsarin gastrointestinal, ana lura da sakamako masu illa ga mafi yawan lokuta. Marasa lafiya sau da yawa suna fuskantar ƙwannafi, tashin zuciya, da amai. Zai yiwu ciwon ciki. Rashin haɓakar stomatitis, colitis, lalacewar lalacewar mucosa na jijiyar ciki, da dai sauransu.

Rashin ruwa shine ɗayan cututtukan da ke lalata jiki don shan maganin.

A ɓangaren fata

A gaban rashin haƙuri ɗaya, fatar fata da itching na iya faruwa.

A gaban rashin haƙuri ɗaya, fatar fata da itching na iya faruwa.

Sau da yawa, marasa lafiya da aka bi da su tare da Phasostabil suna da urticaria. Canjin anaphylactic da ciwan Quincke na iya haɓaka.

Aikace-aikace don aikin hanta mai rauni

Ga marasa lafiya da rage yawan aikin hanta, ana bayar da maganin ne kawai gwargwadon tabbatattun alamu.

Ga yara, ba a sanya wannan magani ba.
Yin amfani da phasostabil yayin daukar ciki ba da shawarar ba.
Yin amfani da phasostabil a cikin lura da marasa lafiya da ke fama da rauni na aiki yana buƙatar kulawa ta musamman.
Ga marasa lafiya da rage yawan aikin hanta, ana bayar da maganin ne kawai gwargwadon tabbatattun alamu.

Abun dacewa

Yayin aikin jiyya tare da phasostabil, yakamata a bar shan barasa.

Yayin aikin jiyya tare da phasostabil, yakamata a bar shan barasa.

Ga magungunan da ke da irin wannan sakamako, sun haɗa da:

1. Cardiomagnyl.
2. Thrombotic ass.
3. Karafarini.
4. Clopidogrel.
5. Wuya

Nazarin likitoci game da Phasostabilus

Vladislav, ɗan shekara 42, Moscow

Marasa lafiya masu tsufa a cikin hadarin kamuwa da cututtukan zuciya galibi ana wajabta su Phasostabil. A mafi yawan lokuta, da farko ina ba da shawarar mafi ƙarancin kashi 20 na mg sannan kuma a hankali ƙara shi. Wannan yana rage haɗarin illa. Kuna buƙatar ɗaukar maganin a cikin dogon karatun.

Irina, 38 years old, Chelyabinsk

A aikace na, sau da yawa nakan tsara Phazostabil ga marasa lafiya da ke da haɗarin thrombosis. Kayan aiki yana rage haɗarin thromboembolism da sauran rikitarwa na thrombosis. Ba da daɗewa ba magani yana haifar da sakamako masu illa ga marasa lafiya. A wannan yanayin, ana buƙatar maye gurbin magani tare da analog.

Neman Mai haƙuri

Igor, dan shekaru 45, Rostov-on-Don

Kimanin shekaru 3 da suka wuce, na fara zuwa asibiti tare da angina pectoris. Bayan ingantawa, likita ya ba da umarnin Phasostabil. Ina shan magani a kowace rana. Yanayin ba ya kara yin muni. Bugu da kari, ƙarancin farashin maganin yana farantawa.

Kristina, shekara 58, Vladivostok

Na dade ina fama da hauhawar jini. Ina shan kwayoyi don daidaita matsin lamba. Kimanin shekara guda da suka wuce, likita ya ba da umarnin Phasostabil, amma magani bai dace da ni ba. Bayan kwaya ta farko, tashin zuciya mai zafi, amai, da zafin ciki ya bayyana. Dole ne in ƙi amfani da wannan kayan aikin.

Alamu don amfani: don wane dalili

Ana nuna Phasostabil don amfani dashi a irin waɗannan halaye:

• a matsayin gwargwadon kariya don hana toshewar jijiyoyin jiki bayan tiyata dangi da tsarin jijiyoyin bugun jini (jijiya da jijiyoyin bugun zuciya da jijiya),
• don hana bayyanar ƙwanƙwasa jini a cikin jijiyoyin bugun jini da kuma sake tsarin ɓarna ta zuciya,
• domin warkewa dalilai da m angina,
• ta hanyar hanyoyin rigakafi na farko don hana ci gaban babban rauni na zuciya da ƙwanƙwasa jini a cikin jijiyoyin jini dangane da asalin abubuwanda ke haifar da su kamar su ciwon suga, hauhawar jini, shan sigari, ƙwayoyin jini mai haɓaka, kiba, tsufa.

Umarni na musamman

Acetylsalicylic acid, wanda shine aiki mai aiki na Phasostabil, na iya haifar da harin asma, bronchospasm da sauran halayen rashin lafiyar jiki.

Riskungiyar haɗarin ta haɗa da mutanen da ke da tarihin asma, rashin lafiyan ga wasu magunguna, cututtukan numfashi na ciki, polyposis a cikin hanci da hanyoyin caji, zazzaɓi (zazzabin hay).

A yayin da za a yi tiyata, ya zama dole a sanar da likita cewa mara lafiya yana shan magungunan da ke ɗauke da acetylsalicylic.

Idan akwai yiwuwar kamuwa da cututtukan cututtukan zuciya da jijiyoyin jiki, ya zama dole a guji yin amfani da asfirin tare da ibuprofen. Idan ana amfani da ibuprofen don sauqaqa jin zafi, ya zama dole a sanar da likita.

Dole ne a ba da gudummawar makonni na farko na magani tare da Phasostabilum da methotrexate (matsakaicin 15 MG a mako) dole ne a ba da gudummawa a kowane mako don gwajin dakin gwaje-gwaje. Kulawa sosai game da halin da ake ciki ya zama dole idan akwai lahani a cikin ayyukan renal (har ma da ƙananan) ga mutanen da ke cikin tsufan tsufa.

Idan ana ba da magunguna masu narkewa ko digoxin a layi ɗaya tare da Phazostabil, ana buƙatar saka idanu abubuwan da ke cikin waɗannan abubuwan a cikin jini jini. Ana bada shawarar yin irin wannan rajistar a farkon matakin jiyya ko a ƙarshen. A wasu halaye, ana iya canza sashi zuwa matakin.

Mahimmanci! Idan an wajabta maganin Phazostabil na dogon lokaci, ya zama dole a gudanar da gwaje-gwajen gwaje-gwaje na farji don kasancewar jinin da yake ɓoye, gwajin jini na asibiti, da kuma bincika yadda tsarin hanta ke aiki.

Acetylsalicylic acid a iyakar adadin yana da karfin tasirin hypoglycemic, wanda dole ne a yi la’akari da shi idan mutum ya kamu da cutar sankarar mellitus.

Shirye-shirye wadanda ke dauke da karancin sakin jiki na acetylsalicylic acid suna taimaka wajan rage fitowar urea, sannan kuma wani lokacin kan haifar da samuwar gout a cikin mutane da ke rage isowar urea wadanda ke iya saurin kamuwa da wannan yanayin.

Tare da mummunan rashin glucose-6-phosphate dehydrogenase, asfirin na iya haifar da haɓakar cutar haemolytic da hemolysis. Riskungiyar haɗarin a cikin wannan yanayin sun haɗa da marasa lafiya suna shan magungunan aspirin na ƙwararrun ƙwayoyi, har ma da mutanen da ke fama da kamuwa da cuta da zazzabi.

A lokacin daukar ciki da lactation

Haramun ne a sha magani yayin shayarwa

Phaauki matakan Phasostabil yana cikin contraindicated a cikin mata a cikin matsayi a lokacin 1st da 3rd. A cikin watanni biyu na biyu, ana iya tsara maganin a cikin maganin yau da kullun na adadin 150% a matsayin magani na ɗan gajeren lokaci.

Kafin ci gaba da aikace-aikacen, wajibi ne don tantance rabo na yuwuwar haɗari ga jariri na gaba tare da fa'ida ga uwa.

Ba shi yiwuwa a yi amfani da Phazostabil wajen shayar da nono.

Phasostabil ko Thrombo Ass: wanda yafi kyau

Wadannan magungunan suna cike da analogues a cikin bangaren aiki. Koyaya, maganin thrombotic ass na samarwa na gida (phasostabil) yana da tasiri kamar wakilin antiplatelet na ƙasashen waje. Bugu da kari, Phazostabil yafi rahusa, wanda shine mahimmin fa'idar wannan kayan aiki.

Phasostabil da Cardiomagnyl: menene banbanci

Cardiomagnyl ana samar da shi ta hanyoyi biyu, bambanci tsakanin shine sashi. Ofaya daga cikin bambancin shine analog kai tsaye na Phazostabil (ya ƙunshi acetylsalicylic acid da magnesium hydroxide a cikin ƙaramin adadin). Sakamakon haka, idan an wajabta Cardiomagnyl tare da abubuwan da ke kunshe a cikin kayan kwalliya a cikin adadin 150 da 30.39 MG (a kowace kwamfutar hannu 1), akwai yuwuwar tasirin zai iya ƙaruwa. Za'a iya samun sakamako mai kyau a wannan yanayin da wuri. Kodayake akwai haɓakar haɓakawa na mummunan halayen halayen cuta. Sakamakon haka, akwai yiwuwar ƙara yawan haɗarin rikitarwa, musamman game da raunin gastrointestinal.

Jerin analogues

Amma game da kwayoyi tare da irin wannan sakamako, a cikinsu ana iya lura da su:

Farashi da sharuddan hutu a cikin kantin magani

Ana iya siyan Phasostabil a cikin kantin magunguna ba tare da takardar izini daga likita ba. Kunshin kunshin allunan 10 tsakanin kuɗin 130-218 rubles.

Nazarin game da miyagun ƙwayoyi suna da inganci galibi. Phasostabil ne sau da yawa ana tsara shi don matsaloli tare da zuciya da jijiyoyin jini, ana ɗaukar shi azaman magani mara lahani da tasiri. Abubuwan da ke faruwa na mummunan halayen halayen jijiyoyi a yayin jiyya tare da wannan magani an lura da su a cikin lokuta masu wuya.

Pharmacodynamics

Ayyukan Phasostabil ya faru ne saboda kaddarorin kayan aikinsa - acetylsalicylic acid (ASA). Hakan ba zai iya hana cyclooxygenase (COX-1) ba, ba tare da ɓata lokaci ba, yana haifar da toshe kwafan ƙwayoyin thromboxane A₂ da kuma tsangwama agaban platelet. An yi imanin cewa ASA tana da wasu hanyoyin don rage haɗarin platelet, wanda ke faɗaɗa girmanta a cikin marasa lafiya da cututtukan jijiyoyin jiki daban-daban. Har ila yau, maganin yana da tasiri, anti-inflammatory da analgesic sakamako.

Magnesium hydroxide - sashi na biyu na aiki na Phasostabil - yana da tasirin antacid, yana kare mucous membrane na jijiyar gastrointestinal (GIT) daga tasirin cutar ASA.

Tare da aikin hanta mai rauni

Phasostabil yana contraindicated a cikin lokuta na hepatic karancin aji na B da C bisa ga rarrabuwa na Yara-Pugh (matsakaici da mai tsanani).

Tare da taka tsantsan, ya kamata a yi amfani da miyagun ƙwayoyi a cikin lura da marasa lafiya tare da aji A ƙarancin hepatic bisa ga ƙididdigar Yara-Pugh (tsananin rauni), ya kamata a sa ido a kan aikin hanta a kai a kai.

Hulɗa da ƙwayoyi

ASA tana haɓaka sakamako kuma yana ƙaruwa da guba na kwayoyi masu zuwa:

• valproic acid - saboda taɓarɓarewa daga sadarwa tare da furotin plasma,
• methotrexate - saboda raguwar karɓar kuɗin yara da kuma taɓarɓarewa daga sadarwa tare da sunadaran plasma.

ASA tana ƙaruwa da haɗarin sakamako masu illa na waɗannan kwayoyi:

• sulfonamides, gami da co-trimoxazole - saboda haɓaka da hankali a cikin ƙwayar jini da ƙaura daga sadarwa tare da sunadaran plasma,
• sauran NSAIDs, magungunan narcotic - saboda yanayin aiki,
• carbonic anhydrase inhibitors, gami da acetazolamide - salicylates sun sami damar kara yawan gubarsu ga tsarin juyayi na tsakiya da kuma yiwuwar bunkasa mummunan acidosis,
• lithium da digoxin - saboda raguwa a hakar su ta asali da kuma raguwar yawaitar plasma,
• zabin yan serotonin na reuptake inhibitors, wadanda suka hada da sertraline da paroxetine - sakamakon gurguntar tare da ASA, hadarin zubar jini daga hanji na sama ya karu,
• wakilai na antiplatelet, ciki har da clopidogrel da dipyridamole, magungunan anticoagulants kai tsaye, ciki har da ticlopidine da warfarin, wakilai na thrombolytic, heparin saboda ƙaura daga manyan tasirin warkewa daga ƙungiyar tare da kariyar plasma jini,
• hypoglycemic na bakin wakilai waɗanda keɓaɓɓu ne na sulfonylureas da insulin - tunda ASA a cikin abubuwan yau da kullun fiye da 2000 mg yana nuna aikin hypoglycemic, a Bugu da kari, yana kwantar da abubuwan da ake samu na sulfonylurea daga haɗin tare da kariyar plasma,
• ethanol da giyar giya - saboda ƙari, sakamakon lalacewar mucosa na ciki da haɓaka kuma lokacin zubar jini yana tsawan lokaci.

Wadannan magunguna masu zuwa suna rage kayan antiplatelet na ASA:

• colestyramine da antacids wadanda ke dauke da sinadarin magnesium da / ko aluminum hydroxide - saboda raguwa a cikin narkewar ASA a cikin narkewa,
• na tsari glucocorticosteroids, ban da hydrocortisone, an wajabta shi azaman sauyawa don cutar Addison - saboda karuwar kawar da salicylates,
• ibuprofen - saboda bayyanar da kaddarorin antagonist dangane da murkushewar tarawar platelet.

A cikin ƙananan allurai, ASA yana raunana sakamako na wakilai na uricosuric (sulfinpyrazone, probenecid, benzbromarone), wanda ya kasance saboda tubular gasa ta kawar da uric acid.

A cikin manyan matakai, ASA yana iya rage tasirin sakamako na diuretics (saboda raguwa a cikin ƙirar fillo na glomerular yayin da yake ƙin ƙaddamar da sinadarin na renal prostaglandins) da magungunan antihypertensive. Musamman, ASA na iya rage tasirin masu hana ACE ta dalilin toshewar ƙirar aikin prostacyclin.

Misalin na Phazostabil sune Agrenox, Antagrex, Aspirin Cardio, Brilinta, Ventavis, Detrombe, Ilomedin, Sylt, Cardiomagnyl, Clapitax, Cardogrel, Clopidogrel, Lirta, Monafram, Plavix, Sanovask, Trombeks, Trombomag da sauransu.

Farashin phasostabil a cikin magunguna

Farashin Phasostabil ya dogara da sashi, yawan allunan a cikin kunshin, kazalika da yankin tallace-tallace da sarkar kantin sayar da magani.Kimanin kuɗin da aka kashe na kunshin na allunan da aka shirya fim 100, 75 MG + 15.2 MG kowane, 133-154 rubles, da kuma MG 150 + 30.39 a kowace - 198-325 rubles.

Yadda ake amfani: sashi da hanya na jiyya

Magungunan farko na cututtukan zuciya kamar su gudawa da kasala masu rauni tare da abubuwan haɗari:

1 kwamfutar hannu na maganin Phazostabil wanda ke dauke da ASA a cikin kashi 150 na MG a ranar farko, sannan 1 kwamfutar hannu 1 dauke da ASA a cikin kashi 75 MG sau ɗaya a rana.

Yin rigakafin infarction na zuciya daga jijiyoyin jini da thrombosis na jini

1 kwamfutar hannu na miyagun ƙwayoyi Fazostabil dauke da ASA a cikin kashi 75-150 MG 1 lokaci kowace rana.

Yin rigakafin thromboembolism bayan tiyata na jijiyoyin jini (jijiyoyin zuciya jijiyoyin bugun jini, percutaneous transluminal na jijiya angioplasty)

1 kwamfutar hannu na miyagun ƙwayoyi Fazostabil dauke da ASA a cikin kashi 75-150 MG 1 lokaci kowace rana.

1 kwamfutar hannu na miyagun ƙwayoyi Fazostabil dauke da ASA a cikin kashi 75-150 MG 1 lokaci kowace rana.

Side effects

A wani ɓangare na tsarin rigakafi: a kai a kai - urticaria, angioedema (edema Quincke), fatar fata, ƙaiƙayi, rhinitis, kumburi na hanci, da wuya - rashin lafiyar anaphylactic, tashin zuciya da jijiyoyin zuciya.

Daga kodan da urinary fili: da wuya - rauni na aikin keɓaɓɓu.

Daga tsarin mai juyayi: sau da yawa - ciwon kai, rashin bacci, lokaci-lokaci - tsananin ƙoshin ciki, bacci, da wuya - tinnitus, ƙwayar cutar cikin ciki.

Akwai rahotannin lokuta na hemolysis da haemolytic anemia a cikin marasa lafiya da raunin glucose-6-phosphate mai ƙarfi.

A bangare na jini da tsarin lymphatic: sau da yawa - zubar jini, da wuya - anaemia, da wuya - aplastic anemia, hypoprothrombinemia, thrombocytopenia, neutropenia, leukopenia, eosinophilia, agranulocytosis.

Daga tsarin numfashi, kirji da gabobin jiki: sau da yawa - bronchospasm.

Daga gastrointestinal fili: sau da yawa - ƙwannafi, sau da yawa - tashin zuciya, amai, infrequently - jin zafi a cikin ciki, ulcers na mucous membrane na ciki da duodenum, ciki har da perforated (da wuya), gastrointestinal na jini, da wuya sosai - stomatitis, esophagitis, cututtukan erosive na babba na ciki (ciki har da tsauraran), colitis, ciwon hanji mai narkewa.

Haɗa kai

Tare da yin amfani da ASA lokaci guda yana haɓaka sakamako kuma yana ƙara haɗarin haɗarin guba:

- methotrexate (saboda raguwar karɓuwa ta renal da kuma gudun hijira daga sadarwa tare da kariyar plasma jini),

- sinadarin valproic (saboda fitarwa daga sadarwa tare da kariyar plasma jini),

ASA tana haɓaka aikin da ƙara haɗarin halayen da ba a so:

- magungunan narcotic, wasu magungunan anti-steroidal anti-inflammatory (saboda aiki tare)

- hypoglycemic jami'ai don maganin baka (abubuwan da suka samo asali na sulfonylurea) da insulin saboda abubuwan da ke tattare da cutar hypoglycemic na ASA kanta a cikin allurai masu yawa (fiye da 2 g kowace rana) da kuma kawar da abubuwanda suka samo asali daga gungun jini tare da sunadarai na jini.

- wakilai na thrombolytic, heparin, anticoagulant mai kai tsaye (ticlopidine, warfarin), jami'in antiplatelet (ciki har da clopidogrel, dipyridamole) - saboda daidaituwa na babban tasirin warkewa da tashin hankali saboda kariyar plasma.