Glyformin don ciwon sukari

Sunan kasa da kasa na miyagun ƙwayoyi shine Metformin. Allunan glyformin suna da ikon magana don rage girman glucose na jini.

Ana ba da shawarar wannan maganin don maganin mellitus-non-insulin-dogara da ciwon sukari mellitus (nau'in ciwon sukari na II) a cikin taron cewa maganin rage cin abinci ba shi da tasiri. A matsayin magani na taimako, ana amfani da Glyformin don maganin ciwon sukari na 1 (insulin-dogara).

Tasirin Gliformin akan jikin mutum an bayyana shi ta hanyoyi guda biyu: a bangare guda, yana hana samuwar glucose a cikin hanta, a gefe guda, yana hana shafar abu a cikin hanji. A lokaci guda, aiwatar da amfani da glucose a cikin tsokoki yana ƙaruwa, kuma ƙwaƙwalwar kyallen takarda zuwa sakamakon insulin yana ƙaruwa.

Yi amfani da ƙuruciya

Yin amfani da magani don magani zai yiwu ne kawai a cikin marasa lafiya waɗanda suka girmi shekaru 10 a cikin tsarin monotherapy kuma a hade tare da insulin. Abunda yake aiki baya tasiri ga haɓaka da haɓakar ɗan haƙuri. Sakamakon rashin bayanai yayin balaga, tsananin sa ido kan yadda ake amfani da miyagun ƙwayoyi ya zama dole. Musamman yara masu shekaru 10-12.

Maganin farko (kwana 3 na farko) bai wuce 500/850 mg / rana ba. A tsakanin makonni biyu, likita ya daidaita alƙawarin, dangane da sakamakon binciken da ke tattare da haɗuwa da sukari a cikin jini. Matsakaicin adadin ba ya wuce 2000 MG.

Don rage mummunan tasirin metformin akan narkewar narkewar abinci, an rarraba tsarin yau da kullun zuwa kashi 2-3 yayin abinci.

Haihuwa da lactation

Tare da biyan bashin wani nau'in ciwon sukari na 2, ɗaukar ciki ta ci gaba tare da cututtukan ƙwaƙwalwa: lalata cuta ta maza, ciki har da mutuwar haihuwa, mai yiwuwa ne. A cewar wasu rahotanni, yin amfani da metformin ba ya tsokani cigaban mahaifa a cikin tayi.

Koyaya, a matakin shirin daukar ciki, yana da kyau a canza zuwa insulin. Don hana karkacewa a cikin haɓakar yaro, yana da mahimmanci ga mata masu juna biyu don sarrafa glycemia da 100%.

Mata masu juna biyu har da masu shayar da mata yayin ciyar da dabi'a, haramun ne ayi amfani da Gliformin. Nazarin game da kasancewar metformin a cikin madara ba a gudanar da su ba.

Lokacin da ake shirin yin juna biyu, ana maye gurbin Glyformin ta hanyar insulin far.

Abubuwan haɗin gwiwa

Alamar bambanci X-ray, wacce take dauke da iodine, tana da ikon tsoratar da tsarin lactic acidosis a cikin masu ciwon sukari tare da tabin hankali na koda. A cikin gwaje-gwajen amfani da irin waɗannan kwayoyi, an tura mai haƙuri zuwa insulin har kwana biyu. Idan yanayin kodan ya gamsu, kwana biyu bayan gwajin, zaku iya komawa tsarin kulawar da suka gabata.

Hulɗa da ƙwayoyi

Magungunan Gliformin Prolong, kamfanin samar da magunguna na kasar Rasha na Akrikhin, ya samar da nau'ikan allunan da aka sanya fim din tare da wani sakamako mai inganci.

Kowane kwamfutar hannu mai launin rawaya biconvex ya ƙunshi 750 MG na aiki mai aiki na metformin hydrochloride da tsofaffin abubuwa: silicon dioxide, hypromellose, microcrystalline cellulose, magnesium stearate.

Allunan kwalaye na 30 ko 60 inji mai kwakwalwa. a cikin akwati fensir mai filastik tare da dunƙule dunƙule da kariyar karewar farko. Ana sanya fakitin filastik a cikin kwali. Rayuwar shiryayye na miyagun ƙwayoyi a cikin bushe, wuri mai duhu a ɗakin zafin jiki shine shekaru 2. Don Gliformin Prolong 1000, farashin akan Intanet ya kasance daga 477 rubles.

Idan kana buƙatar maye gurbin maganin, likita zai iya amfani da analogues tare da kayan tushe guda:

Formmetin
Metformin
Glucofage,
Metformin Zentiva
Gliformin.

Idan mai ciwon sukari ya riga ya dauki magungunan tushen tushen Metformin waɗanda ke da tasirin sakin al'ada, to lokacin da ake maye gurbinsu da Gliformin Prolong, mutum ya kamata ya mai da hankali ga sashin yau da kullun da ya gabata. Idan mai haƙuri ya ɗauki metformin na yau da kullun a cikin kashi fiye da 2000 MG, sauyawa zuwa glyformin mai tsawo ba shi da amfani.

Idan mai haƙuri ya yi amfani da wasu wakilai na hypoglycemic, to, lokacin da ake maye gurbin maganin tare da Gliformin Prolong ana iya jagorantar su da daidaitaccen sashi.

Hakanan ana amfani da Metformin a cikin nau'in ciwon sukari na 2 a hade tare da insulin. Yawan farawa na Glyformin Tare da irin wannan hadaddun jiyya shine 750 mg / rana. (liyafar maraba guda daya). Sashi na insulin an zabi shi ne don yin la'akari da karatun glucoseeter.

Matsakaicin gwargwadon damar halayen na tsawon sa shine 2250 MG (3 inji mai kwakwalwa). Idan ciwon sukari bai isa cikakken ikon cutar ba, an canza shi zuwa nau'in magani tare da sakin al'ada. Don wannan zaɓi, matsakaicin kashi shine 3000 MG / rana.

Idan aka rasa lokacin ƙarshe, kuna buƙatar ɗaukar magunguna a farkon damar. Ba shi yiwuwa a ninka na yau da kullun a wannan yanayin: miyagun ƙwayoyi suna buƙatar lokaci domin jiki ya iya shanshi daidai.

Bai kamata a rubuta Gliformin don ketoacidosis ba, cututtukan hanta na koda, cututtukan cututtukan mahaifa, zuciya, gazawar huhun ciki, a lokacin daukar ciki, shayarwa, infarction na zuciya, yawan wuce gona da iri ga abubuwan da ke cikin miyagun ƙwayoyi.

An tsananta ɗaukar magani don cututtukan cututtukan etiology, kafin gudanar da mummunan aikin tiyata.

Inganta tasirin hypoglycemic na amfanin guda na metformin tare da abubuwan da aka samo asali:

karin bayani,
insulin
acarbose,
magungunan anti-mai hana kumburi,
inhibitors na FAD-dependano aminoxidase da angiotensin suna canza enzyme,
karafarini
Kayakin

Lokacin yin jiyya, zai yiwu a lasafta sakamakon da ba a so yayin la'akari da hada magunguna da sauran magunguna:

Kada a dauki allunan Gliformin Prolong allunan dauke da X-ray dauke da abubuwa masu dauke da aidin.
Haramun ne a hada magani da giya ko kwayoyi masu dauke da giya.
Glyformin Prolong ba a son shi don haɗaka tare da GCS, tetracosactide, on-2-adrenergic agonists, cloprozamine da sauran magunguna tare da tasirin hyperglycemic kai tsaye. Idan ya cancanta, irin waɗannan haɗuwa suna buƙatar daidaitawa sashi.
Amfani da aiki tare da diuretics yana tsokani lactic acidosis.
Haɗin haɗarin metformin tare da salicylates, insulin, sulfonylurea yana haɓaka hypoglycemia.

Idan yayin jiyya tare da Gliformin Ci gaba mai haƙuri an wajabta duk wasu kwayoyi, ya zama dole don bayyana fasalin haɗin gwiwarsu.

Ana shawarar Gliformin don amfani dashi ko dai tare da abinci, ko bayan shan shi, allunan shan ruwa tare da wadataccen ruwa.

A cikin makonni biyu na farko na jiyya (matakin farko na far), yawan maganin yau da kullun da aka yi amfani da shi ya zama bai wuce 1 g ba. Yawancin hankali yana ƙaruwa, amma ana yin la’akari da ƙuntatawa - ƙarancin kiyaye magani ya zama bai wuce 2 g kowace rana ba, ya kasu kashi biyu zuwa uku a rana.

Idan mai haƙuri ya wuce shekara 60, to matsakaicin adadin maganin ba ya wuce 1 g kowace rana.

Yadda ake amfani dashi yadda ya kamata

Glyformin Prolong anyi nufin amfani dashi ne a ciki. Ana ɗaukar kwaya sau ɗaya - da maraice, tare da abincin dare, ba tare da tauna ba. Maganin likita yana ƙaddara yawan likita, la'akari da sakamakon gwaje-gwaje, matakin cutar sukari, cututtukan ci gaba, yanayin gaba ɗaya da amsawar mutum ga maganin.

A matsayin maganin farawa, idan mai ciwon sukari bai taɓa ɗaukar magunguna na metformin ba, ana ba da shawarar yin allurar farko a cikin 750 MG / rana. hada magunguna da abinci.

A cikin makonni biyu ya rigaya ya yiwu a kimanta tasiri na kashi da aka zaɓa kuma, idan ya cancanta, a yi gyare-gyare. Slow titration na sashi na taimaka jiki daidaitawa ba tare da wahala ba da rage yawan sakamako masu illa.

Tsarin daidaitaccen magani shine 1500 MG (Allunan 2), ana ɗauka sau ɗaya. Idan ba za ku iya samun nasarar da ake so ba, zaku iya ƙara yawan allunan zuwa 3 (wannan ita ce adadin mafi girma). An kuma ɗauke su a lokaci guda.

Ana amfani da Gliformin sosai gwargwadon rubutaccen likita a cikin magunguna waɗanda ke da alaƙa da yanayin haƙuri da takamaiman matakin glucose.

Mahimmanci! Take hakkin sashi na miyagun ƙwayoyi na iya haifar da sakamako masu illa da rage tasirin magani.

Gliformin yana farawa tare da ƙananan allurai, bayan ɗan lokaci adadin ƙwayar yana ƙaruwa, sannu a hankali yana zuwa zuwa matakan tabbatarwa.

Allunan ya kamata a ɗauka duka, ba tare da murƙushewa da tauna ba, tare da abinci ko kuma nan da nan bayan cin abinci. Dole ne a wanke maganin tare da gilashin ruwa. Don rage mummunan sakamako na miyagun ƙwayoyi akan tsarin narkewa, ana rarraba kashi na yau da kullun sau 2-3 (dangane da irin maganin).

Bayyanar cututtukan sukari - bidiyo

Alamu don amfani da miyagun ƙwayoyi sune nau'in sukari na 2 na ciwon sukari, lokacin da tsayayyen abinci da kwayoyi na ƙungiyar sulfonylurea basu da tasirin da ake so. Hakanan ana wajabta Glyformin don ciwon sukari na 1 a matsayin haɗin kai don injections na insulin.

Yayin aikin, dole ne a sa ido kan aikin kodan, aƙalla a kowane watanni 6 ana bada shawara don yin bincike don tantance maganin lactate a cikin jini.

Allunan za a iya bugu lokacin abinci ko bayan abinci, ainihin sashi ya kamata a wajabta shi daban-daban daga likitan halartar, la'akari da sakamakon gwajin sukari na jini:

a farkon far, kashi ba ya wuce gram 1 a kowace rana,
bayan kwanaki 15, adadin kudaden yana ƙaruwa.

Daidaitaccen matakin kiyayewa bai wuce 2 grams a rana ba, dole ne a rarraba shi akan allurai da yawa. Masu ciwon sukari na tsufa na kwana ɗaya ana bada shawara don ɗaukar nauyin 1 gram na miyagun ƙwayoyi.

Ba'a ba da shawarar yin amfani da miyagun ƙwayoyi a cikin marasa lafiya waɗanda suka girmi shekaru 60 waɗanda suke yin aiki na zahiri, wanda ke da alaƙa da haɓakar haɗarin haɓakar lactic acidosis a cikinsu. A cikin marasa lafiya tsofaffi, shawarar da aka ba da shawarar yau da kullun kada ta wuce 1 g.

Likitocin da ke halartar sun yanke hukunci kan sigar magani a bisa nazarin matakan glucose na jini.

Sigar farko a farkon farfajiya shine 500-1000 mg / day. Bayan makonni 2, yana iya ƙaruwa dangane da matakin glycemia. Sigar da aka saba shine 1.5-2 g / day, matsakaicin shine 3000 MG. Don rage tasirin mummunar ƙwayar cutar a kan narkewa, ana rarraba kashi zuwa kashi biyu.

Kwayoyin Glyformin suna ɗaukar umarnin don amfani da abincin abinci - zai fi dacewa da yamma. Kwayoyin an hana su cizo, murkushe - dole ne a haɗiye su gaba ɗaya. An ƙayyade sashi da tsawon lokacin warkewa dabam ga kowane mai haƙuri gwargwadon alamun alamun glucose a cikin jini.

Shawarar farko da aka ba da shawarar don kashi ɗaya shine 500 MG, ana ƙididdige yawan allurai daban-daban (an ba shi damar sha har sau 3 a rana ko shan Gliformin 1000 MG a kashi ɗaya). An ba shi izinin ƙara sashi zuwa 850 mg x 1-2 p./d. Idan likita ya ga ya zama dole, to a hankali ana ƙara ƙwayoyi zuwa matsakaicin matakan - 2-3 g kowace rana.

Monotherapy ga yara

Magungunan ba su da amfani ga yara 'yan ƙasa da shekara 18. Idan akwai alƙawarin, sashi zai iya zama ga yara sama da 10 da suka wuce 500-850 MG kowace rana don ɗayan kashi ɗaya.

Hakanan zai yuwu nadin 500 MX x 2 p. / d

Idan ya cancanta, haɓaka sannu a hankali yana yiwuwa. Bayan kwanaki 10-15 bayan farawar gudanarwa, dole ne a aiwatar da gyaran adadin kwayoyi daidai da karatun matakan glucose na jini.

Tare da ƙwaƙƙwarar magani, tare da insulin, sashi na farko na Gliformin shine 500-850 MG tare da mitar gudanarwa na 2-3 r / s. Yawan insulin ana sarrafa shi ta hanyar karatun glucose.

A lokacin daukar ciki da shayarwa

An sani cewa decompensated ciwon sukari mellitus a lokacin lokacin haihuwa yana haifar da barazanar ci gaban mahaifa da cututtukan cututtukan jini a cikin tayin, mutuwa a cikin lokacin haihuwarsa.

An tsara magungunan don sarrafa nau'in ciwon sukari na 2, musamman ga marasa lafiya masu kiba masu yawa, idan gyaran rayuwa ba ya ba da diyya glycemic 100%.

Ana amfani da maganin duka a cikin monotherapy kuma a cikin hadaddun jiyya tare da sauran allunan rigakafin ƙwaƙwalwa ko insulin a kowane mataki na cutar.

Magungunan hana amfani da Gliformin na iya zama:

rikicewar data kasance a hanta da kodan,
kasancewar cutar sikari, lactic acidosis ko ketoacidosis (gami da tarihi)
zuciya ko rashin numfashi,
m yawaitar infarction,

Abinda ya sabawa amfani da Gliformin shine babban cin zarafin yaduwar mahalli

Ba za a iya gudanar da magani na magani ba idan mai haƙuri ya kamu da cututtukan da ke tafe:

gajiyawar zuciya, hadarin kwakwalwa, gazawar numfashi da tazarar jini,
precoma da ciwon sukari
lactic acidosis
mai ciwon sukari ketoacidosis,
matsanancin ƙwayoyin cuta, rashin ruwa da hypoxia.

Bai kamata a kula da mara lafiya tare da magani ba idan akwai karuwar kamuwa da kayan aiki. Yin amfani da miyagun ƙwayoyi a lokacin ayyukan tiyata tare da sadar da maganin insulin ba da shawarar ba.

- nau'in ciwon sukari na 2 na rashin daidaituwa tare da rashin daidaituwa game da maganin rage cin abinci (musamman a cikin marasa lafiya tare da kiba) azaman monotherapy ko a hade tare da sauran magunguna na hypoglycemic.

A miyagun ƙwayoyi yana da wadannan contraindications:

Ketoacidosis yanayi ne mai haɗarin gaske wanda ke tasowa tare da cikakken ko rashin kasancewar insulin,
Cutar sankarau - rashiwar hankali da rashin amsawa,
Lactic acidosis shine matsanancin tara ruwan lactic acid,
Kwayoyin cuta da cututtuka na kodan, hanta,
Zuciya, amai,
Myocardial tsoka rauni,
Lactation da ciki
Cututtukan cututtuka, raunin raɗaɗi,
Za a fara aiwatar da mummunan aiki da sannu

Tare da ƙarancin inganci, ana tsara maganin rage cin abinci ga marasa lafiya da ke fama da ciwon sukari na 2. Gliformin ya tabbatar da kansa a cikin yaki da kiba. Yana yiwuwa a yi amfani da maganin a matsayin monotherapy, kamar yadda kuma a hade tare da wasu magunguna waɗanda ke rage matakan sukari na plasma.

ciwon sukari
mai ciwon sukari ketoacidosis,
cututtukan da ke haifar da tsokawar ƙwayar tsoka (ƙarancin lalacewa na zuciya, gazawar hanji),
mai illa na yara da kuma hepatic aiki,
m shisshigi a cikin abin da insulin far ne contraindicated,
mummunan rauni
barasa saboda hadarin m maye,
ciki da lactation
biye da tsarin karancin kalori (kasa da 1000 kcal / day),
susara yawan mai saurin kamuwa da abubuwan da ke cikin miyagun ƙwayoyi.

48 awanni kafin karatun rediyo ta amfani da wakilai masu bambanci (iv), an dakatar da maganin. Yana dawowa kwana biyu bayan hanya bisa ga sakamakon matakan sukari na jini.

An hana kwayoyi don yin magani ga marasa lafiya da:

Babban matakin hankali game da abubuwan da ke tattare da kwayoyi
Matsalolin ciwon sukari (ketoacidosis, precoma, coma)
Hanta da / ko gazawar koda
Yanayin m wanda zai iya tayar da hankali aiki aiki, hadaddun cututtuka
Haɓakawa da cututtuka wanda akwai haɗarin hypoxia nama (gami da matsanancin rashin ƙarfi na zuciya, ƙoshin zuciya, da sauransu).
Gabannin aikin tiyata da raunin da aka wajabta wa kansa aikin insulin
Rashin aikin hanta
Alcoholism, guba mai guba
Ciki
Lactic acidosis, ana samunsa a lokacin alƙawura ko cikin tarihi
Yin amfani da wakilan bambanci tare da aidin don gudanarwar jijiyoyin bugun jini
Karkashin shekaru 18 (saboda karancin ilimin illolin magunguna ga mutanen wannan rukunin).

Yin amfani da Gliformin yana haɓakawa a gaban waɗannan cututtukan masu zuwa a cikin haƙuri:

Yanayin hypoglycemic, n. masu fama da cutar sankara
ketoacidosis wanda ya danganta da cututtukan jini,
fahimi ga abubuwan da ke cikin miyagun ƙwayoyi,
ciki da shayarwa.

A gaban cututtukan cututtukan cututtuka na cututtukan cututtukan zuciya na cututtukan ƙwaƙwalwar ƙwayar cuta a cikin mummunan yanayin, ya kamata a biya babbar kulawa ga zaɓin sashi na dole.

Side effects

Metformin shine ɗayan amintattun magunguna waɗanda aka gwada ta lokaci da karatu da yawa. Hanyar tasirin sa ba ya motsa samar da insulin nasa ba, sabili da haka, hypoglycemia yayin monotherapy baya haifar da glyformin tsawan lokaci.

Babban haɗari mafi haɗari shine rikicewar gastrointestinal, wanda ya dogara da halayen mutum na jiki da wucewa bayan daidaitawa ba tare da maganin likita ba. Ana kimanta yawan tasirin sakamako daidai da ƙimar WHO: