Sabuwar insulin Tujeo SoloStar: sake duba masu ciwon sukari

Sabuwar insulin basal yana ba da ƙarin kwarin gwiwa na sarrafa glycemic a cikin sa'o'i 24 tare da ƙananan haɗarin cutar hypoglycemia idan aka kwatanta da
tare da magani Lantus,,,

Moscow, Yuli 12, 2016 - Kamfanin Sanofi ya sanar da karɓar takardar shaidar yin rajista a Rasha don miyagun ƙwayoyi Tujo SoloStar® (insulin glargine 300 IU / ml), an yarda da insulin basal mai aiki don amfani don maganin nau'in 1 da nau'in ciwon sukari na 2 a cikin manya. Ana sa ran kashi na farko na sabon insulin a cikin watan Satumbar 2016.

Dangane da Nazarin NATION All-Russian Epidemiological Study a Rasha, kusan marasa lafiya miliyan 6 masu kamuwa da ciwon sukari na 2. Fiye da 50% na marasa lafiya ba su cimma ingantaccen matakan glycemia ba.

“Kimanin shekaru ɗari ke nan, hanyoyin da ake bi don magance cututtukan siga sun ci gaba. A duk tsawon wannan lokaci, ba wai kawai mun sami nasarori ba ne a cikin ilimin likita, har ma da tara bayanan kimiyya waɗanda ke buɗe sabbin hanyoyin cutar da ke sa burin jiyya ya zama mafi himma. Tare da haɓaka ingantaccen magani don lura da ciwon sukari, muna samun kayan aiki wanda zai ba mu damar kafa maƙasudi mafi himma a cikin lura da ciwon sukari, wanda ke da haɓaka tsinkaye da ingancin rayuwar marasa lafiya. A yau, wannan magani shine insulin Tujeo, kuma muna da damar da za mu yi amfani da kayan aikinsa na kirki a cikin aikin asibiti na Rasha. Dangane da bayanan da suka rigaya, Tujeo yana da fa'ida dangane da yawan narkarwar yawan jini da kuzarin nauyin jikin mutum idan aka kwatanta shi da insulin Lantus, sannan kuma yana kiyaye gado a cikin abin da ya tabbatar da lafiyar zuciya da rashin lafiyar oncological. Mun tara shekaru da yawa na kyakkyawar ƙwarewa tare da insulin glargine 100 IU, a yau muna da damar da muke da masaniya da sabon glargine, ”in ji MV Shestakova, Member na ofungiyar Kwalejin Kimiyya ta Rasha, Daraktan Cibiyar Ciwon sukari, FSBI ESC.

Rajistar sabon magani yana kan sakamakon shirin bincike na asibiti na EDITION, wanda jerin manyan gwaje-gwaje ne na kasa da kasa na III don kimanta tasiri da amincin Tujeo idan aka kwatanta da Lantus, inda sama da marasa lafiya 3,500 suka halarta. A cikin binciken, sabon insulin ya nuna ingantaccen inganci da ingantaccen bayanin martabar aminci. Yin amfani da Tujeo ya kasance tare da ƙaramar haɗarin hawan jini a cikin mutane masu ciwon sukari. Sabbin insulin kuma sun nuna ingantaccen tsarin aikin cigaba da ƙananan bambancin glycemic idan aka kwatanta da Lantus na tsawon awanni 24 ko sama da 4.

"Samuwar sabon insulin a cikin taswirar kamfanin shine muhimmin ci gaba a tarihin Sanofi kusan shekaru 100 na ciwon sukari. Muna ci gaba da haɓakawa da tallata sababbin magunguna don biyan bukatun mutane masu ciwon sukari. Tujeo tare da bayanin martaba mai zurfi da kuma tsawaitawa, wanda yake daidai da ingancin insulin Lantus da ingantaccen aminci, na iya taimakawa wajen ƙara yawan marasa lafiyar da suka cimma burinsu na mutum .. Ba wai kawai muna gabatar da wani sabon magani bane ga kasuwar Rasha, amma kuma a cikin tsarin shirin Farma 2020 Mun sanya shi cikin samarwa a masana'antar Sanofi-Aventis Vostok, muna farawa da shirya kayan sakandare a cikin 2016.An shirya cikakken zagayowar don 2018, "sharhi Oksana Monzh, shugaban sashin kasuwanci na shirye-shiryen endocrine Sanofi Russia.

Game da Tujeo

Tujeo yana wakiltar sabon ƙarni na insulin na aiki na yau da kullun. Magungunan ya ƙunshi sau uku yawan raka'a na abu mai aiki a cikin 1 ml na bayani (300 IU / ml), wanda ke canza mahimman kayansa5. Tujeo yana ba da jinkirin sakin insulin da sakinsa a hankali a cikin hanyar jini, kazalika da sakamako mai dorewa, wanda ke haifar da ingantaccen iko da matakan glucose na jini tsawon awanni 24 da ƙananan haɗarin hauhawar jini idan aka kwatanta da Lantus 1, 2, 3, 4.

An yarda da Tujeo don amfani akan nahiyoyi 5, a cikin kasashe 34, gami da kasashe membobin EU, Iceland, Liechtenstein, Norway, Japan da Amurka.

Game da Sanofi

Sanofi yana daya daga cikin shugabannin duniya na kiwon lafiya. Kamfanin yana haɓakawa da aiwatar da hanyoyin samar da mafita don biyan bukatun marasa lafiya a duniya. Sanofi ya kwashe shekaru 45 yana aiki a Rasha. Kamfanin yana daukar sama da mutane dubu biyu a Rasha. A yau, Sanofi yana ɗaya daga cikin shugabanni a kasuwar magunguna ta Rasha, yana ba wa marassa lafiya nau'ikan magunguna na asali da kuma ƙwararru a cikin ɓangarorin warkewa, irin su ciwon sukari, oncology, cututtukan zuciya, cututtukan ciki, cututtuka na tsarin juyayi na tsakiya, alurar riga kafi da wuya cututtuka.

Game da masana'antar Sanofi-Aventis Vostok

A shekara ta 2010, an ƙaddamar da babban masana'antar samarwa ta Sanofi-Aventis Vostok CJSC a Yankin Oryol. A yanzu wannan shine farkon kuma tsire-tsire kawai a cikin Rasha don samar da insulin mafi yawan ƙwayar cuta. Thearfin samarwa na shuka ya isa don biyan bukatun kasuwannin Rasha da ƙasashen CIS a cikin insulin na zamani. A watan Yuli na shekara ta 2015, shukawar Sanofi-Aventis Vostok ta sami nasarar wucewa da binciken Turai tare da karbar takardar GMP na Hukumar Magungunan Turai (EMA), wanda zai ba da damar fitar da insulin da aka samar a Orel zuwa kasashen Tarayyar Turai.

Game da ciwon sukari

Ciwon sukari mellitus cuta ce mai ta'azzara, cuta wacce a duk duniya ke ci gaba da haɓaka. Fiye da mutane miliyan 400 a duniya suna fama da ciwon sukari a halin yanzu, kuma nan da 2040, a cewar masana, adadinsu zai wuce miliyan 640. Wannan kusan miliyan 10 ne ke faruwa a kowace shekara.

Bayanai kan yawan mutanen da ke fama da ciwon sukari a cikin Rasha har zuwa kwanan nan an iyakance su sosai saboda ƙarancin manyan nazarin cutar, tun da yanzu rajista na marasa lafiya yana yin la’akari da kamuwa da cuta kawai.

Godiya ga NATION, babban binciken annoba na Rasha, an samo bayanai na ainihi akan ainihin tasirin nau'in ciwon sukari na 2 a cikin Tarayyar Rasha, wanda shine kashi 5.4%, wato, kusan mutane miliyan 6. Daga cikin waɗannan, fiye da rabi ba su da masaniya game da cutar, kuma kusan 40% suna cikin matakin lalata. Kusan kashi 20% na yawan jama'a suna cikin haɗari, kamar yadda suke da ciwon suga. Cibiyar Nazarin Kasafin Kasuwanci ta Gwamnatin Tarayya ce ta kirkiro karatun NATION a matsayin wani bangare na wata yarjejeniyar da aka sanya hannu tsakanin Cibiyar Kasafin Kudi ta Tarayya ta Cibiyar Kimiyya ta Kasa da Sanofi Russia a ranar 28 ga Fabrairu, 2013 a Kremlin a gaban Shugabannin Rasha V. Putin da Faransa F. Hollande.

Cutar sankara tana da tsadar tattalin arziki. Kusan 12% na jimlar lafiyar lafiya ana kashewa a kan cutar sankara a duniya. Ciwon sukari mellitus da rikice-rikice na ɗaya daga cikin manyan abubuwanda ke haifar da nakasa da mace-mace a cikin jama'a, haɗe da na masu aiki. Kudaden kasafin kuɗin marasa lafiya ga marasa lafiya waɗanda suka haifar da rikice-rikice na ciwon sukari sun fi girma fiye da farashin don marasa lafiya ba tare da rikitarwa ba. Mahimmin mahimmancin tabbatar da iko a kan nauyin tattalin arziki na ciwon sukari suna ci gaba da kasancewa cikin yanayin gano lokaci, kazalika da ingantaccen magani mai lafiya tare da magunguna na zamani, gami da sabon ƙarni na insulin.

Sanarwar Sadarwa ta Sanofi Russia
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Yki-Järvinen H, et al. Kula da ciwon sukari na 2014, 37: 3235-3243.

Gida P., et al. Kula da ciwon sukari na 2015, 38: 2217-2225.

Ritzel, R. et al. Ciwon sukari Metab. 2015, 17: 859–867.

Becker RH, et al. Kula da ciwon sukari a shekara ta 2015, 38 (4): 637–643.

Umarnin don amfani da Tugeo SoloStar®

An gudanar da binciken ne a kan shirin Cibiyar Nazarin Kimiyya ta Tarayya ta Kasa (ESC) ta Ma'aikatar Lafiya ta Tarayyar Rasha tare da Sanofi Rasha don tantance hakikanin halin da ciwon sukari na 2 a Rasha a 2013-2014.

Dedov I., et al. Rashin Tsarin Type 2 na ciwon sukari mellitus (T2DM) a cikin yawan mutanen Rasha girma (Nazarin NATION). Binciken Ciwon sukari da kuma Aikin Likita na 2016, 115: 90-95.

Diungiyar Ciwon Ilimin Cutar ta Internationalasa. IDF na Ciwon Cutar Atlas, 7th edn. Brussels, Belgium: Diungiyar Ciwon Ilimin Hauka ta Duniya, 2015. http://www.diabetesatlas.org.

Omelyanovsky V.V., Shestakova M.V., Avksentieva M.V., Ignatieva V.I. Harkokin tattalin arziki na ciwon sukari a cikin aikin gida. Fasahar likita: Nazari da Zabi, 2015, Na 4 (22): 43-60.

Me yasa muke buƙatar allura?

Cutar ciwon sukari nau'in 2 ana nuna shi ta hanyar gurɓatar ƙwayar hanji da raguwa a cikin ayyukan ƙwayoyin beta, waɗanda ke da alhakin samar da insulin.

Wannan tsari ba zai yuwu ba amma zai shafi matakan glucose na jini. Wannan za'a iya fahimta godiya ga glycated haemoglobin, wanda ke nuna matsakaicin matakin sukari a cikin watanni 3 da suka gabata.

Kusan duk masu ciwon sukari dole ne a hankali kuma su tantance mai nuna su a kai a kai. Idan ta fi ƙarfin girma fiye da yadda aka saba (a bango na tsawaitawa tare da matsakaicin yiwuwar suturar Allunan), to wannan shine tabbataccen abin da ake bukata don sauyawa zuwa tsarin kulawa da insulin.

Kimanin kashi 40 cikin dari na masu ciwon sukari na 2 suna buƙatar allurar insulin.

Compan uwanmu waɗanda ke fama da cutar sukari, ci gaba da allura 12-15 bayan fara cutar. Wannan na faruwa tare da haɓaka mai girma a cikin sukari da kuma raguwa cikin haemoglobin mai glycated. Haka kuma, mafi yawan wadannan masu cutar suna da manyan rikice-rikice dangane da cutar.

Likitocin sun bayyana wannan tsari ta hanyar rashin iya biyan ka'idodin ƙasashen duniya, duk da kasancewar duk kimiyoyin kimiyyar zamani. Daya daga cikin manyan dalilan wannan shine tsoron masu ciwon sukari na allurar rayuwa.

Idan mai haƙuri da ciwon sukari bai san insulin da ya fi kyau ba, ya ƙi canzawa zuwa injections ko ya daina yin su, to wannan shine babban adadin sukarin jini. Irin wannan yanayin na iya haifar da ci gaban rikitarwa mai haɗari ga lafiyar da rayuwar masu ciwon sukari.

Fitaccen hormone da aka zaɓa yana taimakawa tabbatar da haƙuri yana da cikakkiyar rayuwa. Godiya ga kayan aikin zamani mai inganci, ya zama mai yiwuwa a rage rashin jin daɗi da raɗaɗi daga injections.

Rashin Tsarin Cutar Jiki

Ba koyaushe za'a iya bada shawarar insulin ba idan kun cika ragowar insulin hormone dinku. Wani dalili na iya zama irin wannan yanayi:

• ciwon huhu
• rikitaccen mura
• sauran mummunan cututtukan cututtukan zuciya,
• da rashin iya amfani da magunguna a allunan (tare da rashin lafiyan abinci, matsaloli tare da hanta da ƙodan).

Sauyawa zuwa allura za'a iya aiwatar dashi idan mai ciwon sukari yana son jagorantar rayuwar rayuwa ko kuma, in babu damar bi ingantaccen tsarin abincin da yake da cikakke.

Inje ba zai yiwu ta kowace hanya ba illa cutar da lafiyar. Duk wani rikice-rikicen da zasu iya faruwa yayin juyawa zuwa allura za'a iya ɗauka kamar daidaituwa ne da daidaituwa. Koyaya, kada ku rasa lokacin da akwai yawan insulin insulin.

Dalilin wannan yanayin ba shine insulin ba, amma tsawan rayuwa tare da matakan sukari wanda bai dace da jini ba. Akasin haka, bisa ga ƙididdigar likita na ƙasa da ƙasa, lokacin da ake canzawa zuwa allura, matsakaicin rayuwar rayuwa da ƙaruwar ingancinta.

Tare da raguwa a cikin matakin glycated haemoglobin da kashi 1, yiwuwar rikitarwa masu zuwa yana raguwa:

• karancin infarction na zuciya (kashi 14),
• yanki ko mutuwa (kashi 43),
• rikitowar microvascular (kashi 37).

Dogo ko gajere?

Don sauƙaƙe ma'anar basal, al'ada ce a yi amfani da daskararrun abubuwa. Zuwa yau, ilimin kimiyyar magunguna na iya bayar da nau'ikan irin waɗannan kwayoyi. Zai iya zama insulin na tsawon lokacin matsakaici (wanda yake aiki har zuwa awanni 16 yana aiki) da kuma matsanancin ɗaukar hoto (tsawonsa ya wuce awanni 16).

Kwayoyin halitta na rukunin farko sun haɗa da:

1. Gensulin N,
2. Humulin NPH,
3. Insuman Bazal,
4. Protafan HM,
5. Biosulin N.

Shirye-shirye na rukuni na biyu:

Levemir da Lantus sun banbanta sosai da sauran magunguna saboda suna da wani yanayi daban daban na jikin mai cutar siga da kuma bayyananniya. Insulin na rukunin farko ya cika da kauri. Kafin amfani, ampoule tare da su ya kamata a mirgine a hankali tsakanin tafin hannu don samo maganin sigar girgiza mai launi. Wannan bambanci shine sakamakon hanyoyi daban-daban na samar da magunguna.

Insulins daga rukunin farko (tsaka-tsakin tsayi) ba su da yawa. Ta wata hanyar, mafi girman hankali shine za'a iya gano shi a cikin aikin su.

Magunguna daga rukuni na biyu ba su da wannan. Waɗannan fasalulluka ne waɗanda dole ne a yi la’akari da su yayin zaɓar madaidaicin sigar insulin. Koyaya, ƙa'idoji na gaba ɗayan abubuwan hormones daidai suke.

Ya kamata a zaɓi ƙarancin insulin na tsawon lokaci lokacinda zai iya zama matakin glucose na jini tsakanin abinci tsakanin iyakokin da aka yarda. Magunguna ya ƙunshi ƙananan hawa da sauka a cikin kewayon daga 1 zuwa 1.5 mmol / L.

Idan aka zaɓi yawan insulin ɗin da kyau, to, glucose ɗin jini kada ya faɗi ko ya yi ƙari. Dole ne a riƙe wannan alamar don awanni 24.

Dole ne a saka insulin da ya kara tsawo a cikin kashi zuwa cinya ko kuma gindi. Saboda buƙatar santsi da sauƙi a hankali, ana hana allura cikin hannu da ciki!

Inje a cikin wadannan yankuna zai ba da sakamako akasin haka. Insulin-gajeran aiki, wanda aka shafa a ciki ko hannu, yana samar da kyakkyawan ganiya daidai lokacin cin abinci.

Yadda ake kwantar da dare?

Likitoci sun bada shawarar masu ciwon sukari su fara yin allurar insulin tsawon lokaci a dare. Plusari, tabbatar da sanin inda za a saka insulin. Idan mai haƙuri bai san yadda za a yi wannan ba, ya kamata ya ɗauki ma'aunai na musamman kowace sa'o'i 3:

Idan mai ciwon sukari mellitus ya ɗanɗana tsalle-tsalle a cikin sukari na wani lokaci (rage ko ƙaruwa), to yakamata a daidaita sashi da aka yi amfani dashi.

A irin wannan yanayin, dole ne a la'akari da cewa karuwar matakan glucose ba koyaushe bane sakamakon rashi na insulin. Wani lokaci wannan na iya zama tabbacin rashin ƙarfin magana na latent, wanda ke ƙaruwa da karuwa a cikin matakan glucose.

Don fahimtar dalilin ƙaruwa na yawan sukari da dare, ya kamata ku yi la’akari da tsaka-tsakin kowace sa'a. A wannan yanayin, akwai buƙatar saka idanu taro na glucose daga 00,00 zuwa 03,00.

Idan za a samu raguwa a ciki a cikin wannan lokacin, to, a mafi yawan lokuta akwai yuwuwar cewa akwai abin da ake kira ɓoyayyen "ƙaddamar da gaba" tare da yin juyi. Idan haka ne, to ya kamata a rage yawan sirin insulin.

Kowane endocrinologist zai ce abinci yana tasiri sosai game da ƙimatar insulin na asali a jikin mai ciwon sukari. Mafi ƙididdigar yawan adadin insulin basal zai yuwu ne kawai lokacin da babu glucose a cikin jinin da ya zo da abinci, kazalika da insulin tare da ɗan taƙaitaccen lokacin fallasa.

Don wannan dalili mai sauƙi, kafin kimanta insulin da daddare, yana da mahimmanci tsallake abincin maraice ko cin abincin dare da yawa fiye da yadda aka saba.

Zai fi kyau kada a yi amfani da gajeren insulin don guje wa hoto mai ƙima na yanayin jikin mutum.

Don lura da kai, yana da mahimmanci mutum yayi watsi da yawan kuzarin da kitsen yayin cin abincin dare da kuma kafin a lura da sukarin jini.Zai fi kyau bayar da fifiko ga samfuran carbohydrate.

Wannan saboda furotin da kitse suna karɓar jiki a hankali kuma suna iya haɓaka matakan sukari da daddare. Halin, bi da bi, zai iya zama cikas ga samun ingantaccen sakamako na insulin basal na dare.

Babban bayani

Insulin yana taka muhimmiyar rawa a jikin mutum. Abin godiya ne a gare shi cewa sel da tsokoki na gabobin ciki suna karɓar makamashi, godiya ga wanda suke iya aiki kullum kuma suna gudanar da aikinsu. Kwayar cutar ta shiga cikin samar da insulin. Kuma tare da haɓakar kowace cuta wanda ke haifar da lalacewar ƙwayoyin jikinta, ta zama sanadin rage raguwar kwayar wannan kwayar. Sakamakon wannan, sukari da ke shiga jiki kai tsaye tare da abinci ba zai shiga rarrabuwa ba kuma ya zauna cikin jini a cikin nau'ikan microcrystals. Sabili da haka fara ciwon sukari mellitus.

Amma yana da nau'ikan biyu - na farko da na biyu. Kuma idan tare da ciwon sukari 1 akwai wani yanki mai rauni ko cikakkiyar farji, to, tare da nau'in ciwon sukari na 2, ƙaramar bambance bambancen ke faruwa a cikin jikin mutum. Cutar koda tana ci gaba da samarda insulin, amma sel jikin sun rasa hankalin sa, saboda hakan ne suka daina daukar makamashi gaba daya. A kan wannan yanayin, sukari baya rushewa har ƙarshe kuma ya zauna cikin jini.

Kuma idan a cikin DM1 yin amfani da kwayoyi dangane da insulin roba, a cikin DM2, don kula da ingantaccen matakin sukari a cikin jini, ya isa kawai a bi tsarin abinci na warkewa, manufar shine a rage yawan cin abinci na yau da kullun na ƙwayoyin carbohydrates masu narkewa cikin sauƙi.

Amma a wasu yanayi, har ma da ciwon sukari na mellitus na nau'in na biyu, bin wani abincin ba ya bayar da sakamako mai kyau, tun da lokaci na farji ya “daina” kuma ya daina samar da kwayar a cikin adadin da ya dace. A wannan yanayin, ana amfani da shirye-shiryen insulin.

Ana samun su ta fuskoki biyu - a allunan da kuma mafita don gudanarwar cikin ciki (allura). Kuma magana game da abin da ya fi kyau, insulin ko allunan, ya kamata a lura cewa injections suna da mafi girman yanayin wahalar jikin mutum, tunda abubuwanda suke aiki suna shiga cikin hanzari cikin jini kuma suna fara aiki. Kuma insulin a cikin allunan farko ya fara shiga ciki, bayan haka sai ya bi tsarin aikin sannan sai kawai ya shiga cikin jini.

Yin amfani da shirye-shiryen insulin ya kamata ya faru ne kawai bayan tattaunawa tare da ƙwararre

Amma wannan baya nufin cewa insulin a cikin Allunan yana da ƙarancin aiki. Hakanan yana taimakawa rage yawan sukari na jini kuma yana taimakawa haɓaka yanayin janar na haƙuri. Koyaya, saboda ƙarancin aikinsa, bai dace ba don amfani dashi a lokuta na gaggawa, alal misali, tare da farawar cutar hyperglycemic.

Short insulin

Insulin Aspart da sunan kasuwanci

Insulin-gajeran aiki shine maganin sinadarin zinc-insulin. Halinsu na musamman shine cewa suna aiki da jikin mutum da sauri fiye da sauran nau'ikan insulin. Amma a lokaci guda, lokacin aikinsu yana ƙare da zarar ya fara.

Irin waɗannan kwayoyi suna shiga cikin subcutaneously rabin sa'a kafin cin abinci hanyoyi biyu - intracutaneous ko intramuscular. Matsakaicin tasirin amfanirsu yana faruwa ne bayan sa'o'i 2-3 bayan gudanarwa. A matsayinka na mai mulkin, ana amfani da kwayoyi na gajeriyar hanya a hade tare da wasu nau'ikan insulin.

Matsakaici Insulin

Wadannan kwayoyi suna narkewa da hankali sosai a cikin kasusuwa masu kasusuwa kuma suna shiga cikin tsarin jini, saboda wannan suna da tasiri mafi dadewa fiye da insulins-gajere. Mafi yawancin lokuta a cikin aikin likita, ana amfani da insulin NPH ko tef insulin. Na farko shine maganin lu'ulu'u na zinc-insulin da protamine, na biyu shine wakili mai hade wanda ya qunshi lu'ulu'u da amorphous zinc-insulin.

Hanyar aiwatar da shirye-shiryen insulin

Matsakaici insulin na dabba da asalin mutum. Suna da magunguna daban-daban. Bambanci tsakanin su shine insulin asalin dan adam yana da babban sinadarin hydrophobicity kuma yana hulɗa da kyau tare da protamine da zinc.

Don kauce wa mummunan sakamako na amfani da insulin na tsawon lokaci, dole ne a yi amfani da shi sosai bisa ga tsarin - sau 1 ko sau 2 a rana. Kuma kamar yadda aka ambata a sama, waɗannan magunguna suna haɗuwa tare da insulins na gajere. Wannan saboda gaskiyar cewa haɗuwarsu suna taimakawa mafi kyawun haɗin furotin tare da zinc, sakamakon abin da yawan ƙwayar insulin gajere aiki ke raguwa sosai.

Wadannan kudaden za su iya hadewa da kansu, amma yana da mahimmanci a lura da sashi. Hakanan a cikin kantin magunguna zaka iya siyan samfuran gauraya da suka rigaya sun dace da amfani.

Dogon aiki insulins

Wannan rukunin magunguna suna da jinkirin matakin ɗaukar jini, saboda haka suna yin aiki na dogon lokaci. Wadannan ma'aikatan rage karfin insulin na jini suna bada daidaituwa na matakan glucose a cikin kullun. An gabatar dasu sau 1-2 a rana, ana zabar sashi daban. Za'a iya haɗe su tare da maɗaukaki na gajere da na matsakaici.

Hanyoyin aikace-aikace

Wani nau'in insulin don ɗauka kuma a cikin menene, kawai likita ya yanke shawara, la'akari da halayen mutum na mai haƙuri, matakin ci gaban cuta da kasancewar rikitarwa da sauran cututtuka. Don sanin ainihin sashin insulin, ya zama dole a sanya idanu a kaikaice matakin sukari a cikin jini bayan gudanarwar su.

Mafi kyawun wuri don insulin shine babban ɓangaren kitse a saman ciki.

Da yake magana game da hormone wanda yakamata ta samar da ita, adadinsa yakamata yakai raka'a 30-40 a kowace rana. Ana buƙatar iri ɗaya a kan masu ciwon sukari. Idan yana da cikakkiyar ƙwayar cutar ƙwayar cutar ƙwayar cuta, to yawan ƙwayar insulin zai iya kaiwa raka'a 30-50 kowace rana. A lokaci guda, yakamata ayi amfani da 2/3 na safe, da ragowar maraice, kafin abincin dare.

Mahimmanci! Idan akwai wani canji daga dabba zuwa insulin na mutum, yakamata a rage sashi na yau da kullun na miyagun ƙwayoyi, tunda jiki yana ɗaukar insulin ta jiki fiye da dabba.

Mafi kyawun tsari don shan miyagun ƙwayoyi ana ɗaukarsa azaman haɗuwa ne na insulin ɗan gajere da matsakaici. Ta halitta, makirci don amfani da kwayoyi kuma ya dogara da wannan. Mafi yawan lokuta a irin wannan yanayi, ana amfani da tsarin masu zuwa:

• amfani da insulin gajere da matsakaici mai aiki a kan komai a ciki kafin karin kumallo, kuma da yamma kawai za a sanya magani mai gajartawa (kafin abincin dare) sannan bayan fewan awanni - matsakaici,
• ana amfani da kwayoyi da ke nuna gajeriyar hanya a cikin kullun (har zuwa sau 4 a rana), kuma kafin zuwa gado, ana gudanar da allurar magani na dogon lokaci ko gajere,
• a 5-6 a.m. ana yin insulin na matsakaici ko tsawaita aiki, kuma kafin karin kumallo da kowace abinci mai zuwa - gajere.

A cikin taron cewa likita ya ba da magani guda ɗaya kawai ga mai haƙuri, to, ya kamata a yi amfani da shi sosai a kan kullun na yau da kullun. Don haka, alal misali, insulin gajeran aiki ana saka shi sau 3 a rana yayin wuni (na ƙarshe kafin lokacin bacci), matsakaici - sau 2 a rana.

M sakamako masu illa

Wani ingantaccen magani da aka zaba da kuma yawan maganin sa kusan bai taɓa tsokano faruwar cutar ba. Koyaya, akwai yanayi lokacin da insulin kanta bai dace da mutum ba, kuma a wannan yanayin wasu matsaloli na iya tashi.

Abunda ke haifar da sakamako masu illa lokacin amfani da insulin shine mafi yawancin lokuta ana alakantawa da yawan wuce gona da iri, kulawa mara kyau ko adana magunguna

Sau da yawa, mutane suna yin gyare-gyare a kan kansu, suna ƙaruwa ko haɓaka adadin insulin a allurar, wanda hakan yakan haifar da rashin sakamako na ruwan lemo. Orara ko rage yawan sashi yana haifar da sauyawa a cikin gulluደም na jini a cikin ɗayan ko kuma hakan, hakan yana haifar da haɓakar ƙwayar hauhawar jini ko hauhawar jini, wanda zai haifar da mutuwa kwatsam.

Wata matsala da masu ciwon sukari ke fuskanta sau da yawa shine halayen rashin lafiyan mutum, yawanci yakan faru ne akan insulin asalin dabbobi. Alamu na farko su ne bayyanar itching da konewa a wurin allurar, kazalika da cutar fata da kumburin su. A yayin da irin waɗannan bayyanar cututtuka suka bayyana, ya kamata ku nemi taimakon likita nan da nan kuma ku canza zuwa insulin na asalin ɗan adam, amma a lokaci guda rage yawan sashi.

Atrophy na adipose nama matsala ce ta yau da kullun a masu fama da cutar siga tare da tsawaita amfani da insulin. Wannan na faruwa ne saboda yawan ayyukan insulin a wuri guda. Wannan ba ya haifar da lahani da yawa ga lafiyar, amma ya kamata a canza yankin allura, tunda matakinsu na narkewa ne.

Tare da yin amfani da insulin na tsawan lokaci, za a iya samun ƙarin yawan ƙwayar cuta, wanda ke bayyane da rauni, ciwon kai, rage karfin jini, da sauransu. Game da yawan abin sama da ya kamata, dole ne yakamata ku nemi likita nan da nan.

Siffar Magunguna

Da ke ƙasa za mu bincika jerin magungunan da ke cikin insulin waɗanda galibi ana amfani da su ne wajen lura da ciwon sukari na mellitus. An gabatar dasu don dalilai na bayanai kawai, baza ku iya amfani dasu ba tare da sanin likita a kowane yanayi. Domin kuɗin don yin aiki da kyau, dole ne a zaɓi su gaba ɗaya!

Mafi kyawun aikin insulin gajere. Ya ƙunshi insulin ɗan adam. Ba kamar sauran kwayoyi ba, yana farawa da sauri. Bayan amfani dashi, ana lura da rage yawan sukari na jini bayan mintina 15 kuma ya kasance cikin iyakoki na yau da kullun don wasu 3 hours.

Humalog a cikin nau'in sirinji na alkalami

Babban alamun alamun amfani da wannan magani sune cututtuka da halaye masu zuwa:

• ciwon sukari wanda yake dogaro da kansa
• sauran rashin lafiyar insulin,
• hawan jini
• juriya ga amfani da magunguna masu rage sukari,
• ciwon sukari wanda yake dogaro da kansa kafin yin tiyata.

An zaɓi kashi na miyagun ƙwayoyi daban-daban. Gabatarwa za a iya aiwatar da duka biyu kuma ya shiga cikin gaba daya, da cikin ciki. Koyaya, don guje wa rikice-rikice a gida, ana bada shawara don sarrafa magunguna kawai a ƙarƙashin kowane abinci.

Magungunan gajere na zamani, gami da Humalog, suna da sakamako masu illa. Kuma a wannan yanayin, a cikin marasa lafiya tare da amfani da shi, precoma mafi yawan lokuta yakan faru, raguwar ingancin hangen nesa, rashin lafiyan jiki da lipodystrophy. Don magani don yin tasiri a kan lokaci, dole ne a adana shi da kyau. Kuma wannan ya kamata a yi a cikin firiji, amma bai kamata a ba shi damar daskare ba, tunda a wannan yanayin samfurin yana asarar kayan aikin warkarwa.

Insulin Lizpro da sunan kasuwanci
Ciwon sukari insulin

Insuman Rapid

Wata magani da ke da alaƙa da insulins-gajere da ta danganci kwayoyin halittar mutum. Ingancin maganin yana isa mafi girman minti 30 bayan gudanarwa kuma yana bayar da tallafin jiki mai kyau na tsawon awanni 7.

Insuman Rapid don tsarin kulawa da ƙasa

Ana amfani da samfurin 20 mintuna kafin kowane abinci. A wannan yanayin, shafin allura yana canzawa kowane lokaci. Ba koyaushe zaka iya yin allura a wurare biyu. Wajibi ne a canza su koyaushe. Misali, lokacin farko ana yin shi ne a yankin kafada, na biyu a ciki, na uku a gindi, da dai sauransu. Wannan zai guje wa atrophy na adipose nama, wanda wannan wakili yakan tsokane shi.

Biosulin N

Wani magani ne na matsakaici wanda ke ƙarfafa ɓarin ƙwayar cuta. Ya ƙunshi nau'ikan hormone mai kama da mutum, sauƙin haƙuri da yawa kuma marasa lafiya suna ƙyamar bayyanar sakamako masu illa. Ayyukan maganin suna faruwa ne sa'a daya bayan gudanarwa kuma ya kai kololuwa bayan sa'o'i 4-5 bayan allurar. Ya kasance yana aiki har tsawon awanni 18 zuwa 20.

A cikin abin da mutum ya maye gurbin wannan magani tare da kwayoyi masu kama da wannan, to yana iya fuskantar matsalar rashin ƙarfi na hypoglycemia. Irin waɗannan dalilai kamar matsananciyar damuwa ko abincin tsallake abinci na iya tsokanar bayyanarsa bayan amfanin Biosulin N. Saboda haka, yana da matukar muhimmanci lokacin amfani da shi don auna matakan sukari na jini akai-akai.

Gensulin N

Yana nufin insulins na matsakaici wanda ke haɓaka haɓakar ƙwayar tsoka. Ana sarrafa magungunan a ƙarƙashin ƙasa. Ingantaccen aikinta shima yana faruwa awa 1 bayan gudanarwa kuma yakanyi tsawon awanni 18 zuwa 20. A takaice ana tsokanar tasirin tasirin sakamako kuma ana iya haɗuwa da ita tare da ɗaukar matakan gajere ko na tsawan lokaci.

Iri na miyagun ƙwayoyi Gensulin