Levemir - umarnin don amfani

"Levemir" magani ne na warkewa wanda aka yi amfani da shi bisa umarnin da aka yi amfani da shi don daidaita matakan insulin, ba tare da la'akari da adadin abincin da aka ɗauka da fasalin kayan abinci ba. Sau da yawa likitocin suna ba da shawarar wannan magani ga marassa lafiyar su rage sukarin jininsu. Abubuwan da ke aiki a cikin kayan sunadarai da kaddarorin suna kama da insulin, wanda aka samar a jikin mutum.

Tsarin saki, abun da aka shirya da marufi

Magungunan kwayoyi ne bayyananne a cikin sirinji mai siyarwa tare da mai watsawa. Ta kasance ta rukuni na wakilai na hypoglycemic. Marufi yana ba ku damar gudanar da aikin insulin a cikin kowane gwargwado - daga 1 raka'a zuwa 60. Daidaitawar sashi mai yiwuwa ne har zuwa raka'a. Za'a iya nuna bambance-bambancen guda biyu na sunan akan kunshin maganin: LEVEMIR FlexPen ko LEVEMIR Penfill.

Babban kayan shine insulin detemir.

Substancesarin abubuwa:

  • glycerol
  • sinadarin sodium
  • metacresol
  • phenol
  • hydrochloric acid
  • zinc acetate
  • hydrogen phosphate bushewa,
  • ruwa.

Marufi yana da launin kore-fari. A cikin LEVEMIR Penfill akwai katakan katako mai dauke da 3 ml na bayani (300 ED) a kowane. Kashi ɗaya ya ƙunshi 0.142 mg na abu mai aiki. LEVEMIR FlexPen an tattara shi a cikin alkalami.

MUHIMMIYA! Lokacin da miyagun ƙwayoyi a cikin kabad ɗin ya ƙare, ya kamata a jefa alkalami!

INN masana'antun

Kamfanin masana'antar shine Novo Nordisk, Denmark. Sunan kasa da kasa mai zaman kansa shine "insulin detemir."

An shirya shiri ne ta hanyar ilimin kimiyyar kere-kere wanda ya danganta da sigar DNA da ta wucin gadi ta amfani da irin ƙwayar Saccharomyces cerevisiae.

Farashin dillalan magani ya bambanta daga 1300 zuwa 3000 rubles. "FlexPen" yana da ɗan kuɗi kaɗan fiye da "PenFill", saboda ya fi dacewa don amfani.

Pharmacology

Levemir alamace ta wucin gadi ta insulin aikin mutum. A wuraren allura, akwai bayyanuwar hadewar kwayoyin insulin da kuma hadewar su da albumin, saboda abu mai aiki a hankali ya shiga kyallen da nufin hakan kuma ba ya shiga cikin jini kai tsaye. Akwai rarraba hankali da shan ƙwayoyi.

Haɗin kwayoyin tare da sunadarai suna faruwa a sashin sarkar acid mai sashin jiki.

Irin wannan injin yana ba da sakamako mai haɗari, wanda ke inganta ingancin ɗaukar abu mai warkewa da sauƙaƙe kwararar ayyukan metabolic.

Pharmacokinetics

Matsakaicin mafi girman abubuwan shine an mai da hankali ne a cikin plasma 6 hours bayan allura. An sami daidaituwa daidai da ita tare da kashi biyu yayin inje 2 ko 3. An rarraba maganin a cikin jini a cikin girman 0.1 l / kg. An samu wannan alamar ne saboda gaskiyar cewa kwayar halitta ba ta da alaƙa da sunadarai, amma ya tattara kuma yana gudana cikin plasma. Bayan rashin himma, ana fitar da samfuran abinci daga jiki bayan sa'o'i 5-7.

An wajabta magunguna don sukarin hawan jini. Amfani da shi don kula da manya da yara daga shekara biyu.

A farkon farawar insulin, ana gudanar da Levemir sau ɗaya, wanda ke taimakawa kyakkyawan sarrafa sarrafa glycemia.

Magunguna yana rage haɗarin hawan jini a cikin dare.

Neman madaidaicin kashi don daidaita al'ada ba shi da wahala. Jiyya tare da Levemir ba ya haifar da samun nauyi.

Lokacin da za'a gudanar da maganin za'a iya zabar shi da kansa. Nan gaba, ba da shawarar canza shi ba.

Umarnin don amfani (sashi)

Tsawon lokacin bayyanuwa ga miyagun ƙwayoyi ya dogara da sashi. A farkon jiyya ya kamata a saka farashi sau ɗaya a rana, zai fi dacewa a kan Hauwa ta abincin dare ko kafin lokacin kwanta barci.Ga marasa lafiya waɗanda ba su sami insulin a baya ba, sashin farko shine raka'a 10 ko raka'a 0.1-0.2 a kowace kilogiram na nauyin jiki na al'ada.

Ga marasa lafiya waɗanda suka daɗe suna amfani da wakilai na hypoglycemic, likitoci suna ba da shawarar kashi 0.2 zuwa 0.4 a kowace kilogiram na nauyin jiki. Ayyukan yana farawa bayan sa'o'i 3-4, wani lokacin har zuwa 14 hours.

Ana amfani da kashi na yau da kullun sau 1-2 a rana. Zaka iya shigar da cikakken kashi nan take sau ɗaya ko raba shi zuwa allurai biyu. A cikin magana ta biyu, ana amfani da miyagun ƙwayoyi da safe da maraice, tazara tsakanin gwamnoni ya zama 12 hours. Lokacin canzawa daga wani nau'in insulin zuwa Levemir, kashi na maganin yana canzawa.

Ana yin lissafin sashi ne ta hanyar endocrinologist bisa ga alamomi masu zuwa:

  • digiri na aiki
  • fasalin abinci mai gina jiki
  • matakin sukari
  • tsananin cutar Patho,
  • ayyukan yau da kullun
  • gaban concomitant cututtuka.

Za'a iya canza warkaswa idan tiyata ta zama tilas.

Side effects

Har zuwa 10% na marasa lafiya suna ba da rahoton sakamako masu illa yayin shan maganin. A cikin rabin shari'o'in, wannan hypoglycemia ne. Sauran tasirin bayan gudanarwa ana nuna su ta hanyar kumburi, redness, zafi, itching, kumburi. Jinya na iya faruwa. Abubuwan da ba su dace ba yakan ɓace bayan weeksan makonni.

Wani lokacin yanayin yana ƙaruwa saboda haɓakar ciwon sukari, takamaiman amsa yana faruwa: ciwon sukari da ciwon mara mai ƙonewa da rashin jin daɗi. Dalilin wannan shine don kula da matakan glucose mafi kyau da kuma sarrafa glycemia. Jikin yana sake tsarawa, kuma lokacin da ya dace da maganin, alamomin basa tafiya da kansu.

Daga cikin mawuyacin halayen, mafi yawan su ne:

  • malfunctioning na tsakiya juyayi tsarin (ƙarar jin zafin ji, ƙarancin na ƙarshen, ƙarancin gani acuity da tsinkaye haske, tingling ko kona ji)
  • rikice-rikice na carbohydrate metabolism (hypoglycemia),
  • urticaria, itching, rashin lafiyan, tashin hankalin anaphylactic,
  • na ciki edema
  • pathology na adipose nama, yana haifar da canji a jikin mutum.

Dukkansu suna fuskantar gyara ta amfani da kwayoyi. Idan wannan bai taimaka ba, likitan ya maye gurbin maganin.

MUHIMMIYA! Ana sarrafa abu ɗin ta hanyar subcutaneously na musamman, in ba haka ba rikice-rikice a cikin nau'i mai ƙarfi na hypoglycemia za a iya tsokani.

Yawan damuwa

Yawan magungunan da zai tsokani wannan hoton na asibiti, kwararru ba su kafa su ba. Tsarin allurai na yau da kullun na iya haifar da yawan kumburi. Harin yana farawa mafi yawan lokuta a cikin dare ko a cikin matsi.

Za'a iya kawar da mai saukin kai da kanka: ku ci cakulan, yanki na sukari ko samfurin da ke da ƙwayar carbohydrate. Wani nau'i mai tsanani, lokacin da mai haƙuri ya rasa hankali, ya ƙunshi gudanarwar ƙwayar cuta zuwa har zuwa 1 mg na glucagon / glucose bayani a cikin jijiya. Wannan kwararren likita ne kaɗai zai iya yin wannan. Idan hankali bai koma ga mutum ba, ana gudanar da glucose bugu da .ari.

MUHIMMIYA! An hana shi cin gashin kansa ko rage shi, da kuma rasa lokacin magani na gaba, tunda akwai yiwuwar samun rashin walwala da tashin hankali na jijiyoyin jini.

Hulɗa da ƙwayoyi

An yi nasarar amfani da Levemir a hade tare da sauran magunguna: jami'in hypoglycemic a cikin nau'ikan allunan ko gajeren insulins. Koyaya, ba a so a gauraya nau'ikan insulin a cikin sirinji iri ɗaya.

Yin amfani da wasu kwayoyi yana canza mai nuna alamun bukatun insulin. Don haka, wakilai na hypoglycemic, anhydrase carbonic, inhibitors, oxidases monoamine da sauransu suna haɓaka aikin abu mai aiki.

Hormones, hana haihuwa, kwayoyi dauke da aidin, magungunan hana haihuwa, danazole sun sami damar raunana tasirin.

Salicylates, octreotide, da reserpine zasu iya yin ƙasa da haɓaka da buƙatar insulin, kuma beta-blockers suna rufe alamun bayyanar cututtuka na hypoglycemia, da hana daidaituwa na matakan sukari.

Abubuwan haɗuwa tare da ginin sulfite ko thiol, kazalika da nau'in maganin jiko, suna da sakamako mai lalacewa.

Insulin Levemir - umarnin, sashi, farashi

Ba zai zama mai wuce gona da iri ba a faɗi cewa tare da isowar insulin analogues wani sabon zamani ya fara a rayuwar masu ciwon sukari.

Saboda tsarin su na musamman, suna bada damar sarrafa glycemia sosai fiye da yadda yake a da. Insulin Levemir yana daya daga cikin wakilan magunguna na zamani, analog of hormone basal.

Ya bayyana ne kwanan nan: a Turai a cikin 2004, a Rasha bayan shekaru biyu.

Levemir ya mallaki dukkanin abubuwan da insulin dogon kwalliya: yana aiki daidai, ba tare da kololuwa na tsawon awanni 24 ba, yana haifar da raguwar hauhawar jini a cikin dare, baya bayar da tasirin gudummawar nauyi ga marasa lafiya, wanda gaskiyane ga nau'in ciwon sukari na 2. Tasirin sa yafi dacewa da ƙarancin dogaro akan halayen mutum fiye da na NPH-insulin, don haka ɗin yafi sauƙin zaba. A wata kalma, ya dace a bincika wannan magani.

Bruef umarnin

Levemir shine mahaifin kamfanin Danish Novo Nordisk, wanda aka san shi da sababbin hanyoyin magance cututtukan ciwon sukari. Magungunan sun sami nasarar wuce gona da iri, ciki har da yara da matasa, yayin daukar ciki.

Duk sun tabbatar ba kawai lafiyar Levemir ba, har ma da ingantaccen tasiri fiye da insulins da aka yi amfani da su a baya.

Gudanar da sukari daidai yake da nasara a cikin nau'in 1 na ciwon sukari kuma a cikin yanayi tare da ƙaramar buƙatar hormone: nau'in 2 a farkon maganin insulin da ciwon sukari na gestational.

Riarin bayani game da magani daga umarnin don amfani:

BayaninMaganin mara launi tare da maida hankali akan U100, cushe a cikin gilashin gilashin (Levemir Penfill) ko alkalami waɗanda basu buƙatar cikawa (Levemir Flexpen).
Abun cikiSunan kasa-da-kasa wanda ba na shi ba ne na kayan aiki na Levemir (INN) shine insulin detemir. Baya ga shi, ƙwayar ta ƙunshi tsofaffi. Dukkanin abubuwan haɗin an gwada su don yawan guba da ƙwayar carcinogenicity.
PharmacodynamicsYana ba ku damar yin tawakkali cikin sakin insulin basal. Yana da bambanci kaɗan, wannan shine, tasirin yana bambanta kaɗan ba kawai a cikin haƙuri guda ɗaya tare da masu ciwon sukari ba a cikin kwanaki daban-daban, har ma a wasu marasa lafiya. Yin amfani da insulin Levemir yana rage haɗarin haɓakar hypoglycemia, inganta haɓakar su. Wannan magani a halin yanzu shine insulin 'tsaka tsaki'-mai tsaka-tsaki, yana da kyau yana shafar nauyin jiki, yana kara bayyanar da cikar jin kansa.
Siffofin tsotsaLevemir yana iya sauƙaƙe hadaddun ƙwayoyin insulin - hexamers, ya ɗaura ƙuraje don sunadarin a wurin allurar, don haka sakinsa daga ƙwayar subcutaneous yana da jinkiri da daidaituwa. Magungunan ba su da babban halayyar Protafan da Humulin NPH.Haɗin masana'antun, aikin Levemir ya fi sauƙi fiye da na babban mai fafatawa daga rukuni na insulin guda ɗaya - Lantus. Ta hanyar aiki, Levemir ya wuce magungunan Tresiba na zamani mafi tsada, kuma Novo Nordisk ya inganta.
AlamuDuk nau'ikan cututtukan cututtukan cututtukan da ke buƙatar maganin insulin don sakamako mai kyau. Levemir yana aiki daidai a kan yara, yara da tsofaffi marasa lafiya, ana iya amfani dashi don keta hakkin hanta da kodan. Tare da nau'in ciwon sukari na 2, ana amfani da amfani dashi tare da haɗin gwiwa tare da wakilai na hypoglycemic.
ContraindicationsBai kamata a yi amfani da Levemir ba:

  • tare da rashin lafiyan ga insulin ko kayan taimako na maganin,
  • don lura da matsanancin yanayin rikice-rikice,
  • a cikin famfo na insulin.

Ana amfani da miyagun ƙwayoyi ne kawai a ƙarƙashin ƙasa, an haramta gudanar da aikin jijiyoyin jini.Ba a gudanar da karatun yara a ƙarƙashin shekaru biyu ba, saboda haka an ambaci wannan rukuni na marasa lafiya a cikin contraindications. Duk da haka, an sanya wannan insulin don yara ƙanana.

Umarni na musammanRagewa da Levemir ko sake maimaitawa na rashin isasshen ƙwayar cuta yana haifar da mummunan cutar hyperglycemia da ketoacidosis. Wannan yana da haɗari musamman tare da ciwon sukari na 1. Yawan wuce haddi, abincin tsallake-tsallake, abubuwan da ba a kula da su ba sun lalace tare da hauhawar jini. Tare da watsi da ilimin insulin da kuma canzawa sau da yawa na abubuwan da ke faruwa a cikin girma da ƙananan glucose, rikice-rikice na ciwon sukari mellitus yana haɓaka da sauri.Haka a cikin Levemir yana ƙaruwa tare da wasanni, yayin rashin lafiya, musamman tare da zazzabi mai zafi, lokacin daukar ciki, farawa daga rabi na biyu. Ana buƙatar daidaita yanayin ƙarfi don kumburi mai kumburi da ƙaruwa da na kullum.
SashiJagororin suna ba da shawarar cewa don nau'in 1 na ciwon sukari, ƙididdigar adadin mutum na kowane mai haƙuri. Tare da nau'in cuta ta 2, sashi yana farawa da raka'a 10 na Levemir kowace rana ko raka'a 0.1-0.2 a kowace kilogram idan nauyin ya bambanta da matsakaici .. A aikace, wannan adadin na iya wuce kima idan mai haƙuri ya bi ƙarancin abincin carb ko kuma yana motsa jiki cikin motsa jiki. Sabili da haka, wajibi ne don lissafin adadin tsawon insulin bisa ga algorithms na musamman, yin la'akari da glycemia a cikin aan kwanaki.
AdanawaLevemir, kamar sauran insulins, yana buƙatar kariya daga haske, daskarewa da zafi mai zafi. Tsarin lalacewa bazai bambanta ta kowace hanya daga sabo, sabili da haka ya kamata a biya kulawa ta musamman ga yanayin ajiya. Karancin da aka buda na tsawon makonni 6 a zazzabi a daki. Ana adana kwalaban ɓoye a cikin firiji, rayuwar rayuwar su daga ranar da aka ƙera shine watanni 30.
FarashiKayan katako 5 na 3 ml (jimlar 1,500 raka'a) na Levemir Penfill farashin daga 2800 rubles. Farashin Levemir Flexpen yana da girma kaɗan.

Menene aikin insulin levemir

Levemir insulin dogon ne. Tasirinsa ya fi na magungunan gargajiya - cakuda insulin mutum da protamine. A cikin kashi kusan raka'a 0.3. a kowace kilogram, maganin yana aiki a cikin sa'o'i 24. Karami da ake buƙata sashi, da gajarta lokacin aiki. A cikin marasa lafiya da ke fama da cutar sankara, ta hanyar rage cin abinci mai ƙarancin carb, aikin zai iya ƙare bayan sa'o'i 14.

Ba za a iya amfani da insulin mai tsayi ba don magance glycemia yayin rana ko a lokacin bacci. Idan an samo sukari mai tsayi da maraice, yana da mahimmanci don yin allura mai mahimmanci na gajeren insulin, kuma bayan shi don gabatar da dogon hormone a cikin kashi ɗaya. Ba za ku iya haɗu da samfuran insulin na dura yanayi iri ɗaya a cikin sirinji iri ɗaya ba.

Sakin Fom

Levemir insulin a cikin kwalliya

Levemir Flexpen da Penfill sun bambanta da nau'i kawai, magungunan da ke cikinsu daidai ne. Penfill - Waɗannan ƙananan katukan ne da za a iya saka su cikin alkalannin sirinji ko nau'in insulin daga gare su tare da ingantaccen sirinji na insulin.

Levemir Flexpen - ya cika kafin ya cika alkalami mai sikelin da aka yi amfani da shi har maganin zai kare. Ba zaku iya sake wahalar su ba. Alkalami yana ba ka damar shiga insulin a cikin rukunin 1 naúrar. Suna buƙatar rarrabe bututun NovoFayn.

Dogaro da kauri daga kasusuwa na nama, musamman bakin ciki (0.25 mm diamita) tsayi 6 mm ko bakin ciki (0.3 mm) 8 mm aka zaɓi. Farashin fakitin allura 100 kusan 700 rubles.

Levemir Flexpen ya dace da marasa lafiya tare da salon rayuwa mai aiki da kuma rashin lokaci. Idan buƙatar insulin ya kasance karami, mataki na 1 naúrar ba zai ba ku damar yin daidai da lambar da ake so ba. Don irin waɗannan mutane, ana bada shawarar Levemir Penfill a hade tare da ƙarin madaidaicin sirinji, misali, NovoPen Echo.

Daidai sashi

Ana daukar adadin Levemir daidai idan ba kawai sukari mai azumi ba, amma haemoglobin da ke cikin glycated yana cikin yawan al'ada. Idan biyan diyya ga masu ciwon sukari bai isa ba, zaku iya canza adadin insulin tsawon kwana 3. Don ƙayyade gyaran da yakamata, mai ƙira ya ba da shawarar ɗaukar matsakaicin sukari a kan komai a ciki, kwanakin 3 na ƙarshe suna haɗuwa da lissafin

Glycemia, mmol / lCanjin yanayinValueimar gyara, raka'a
1010

Labari mai alaƙa: dokoki don ƙididdige yawan insulin don allura

Tsarin allura

  1. Tare da nau'in ciwon sukari na 1 Koyarwar ta ba da shawarar gudanar da aikin insulin na lokaci biyu: bayan farkawa da kuma kafin lokacin bacci. Irin wannan makirci yana ba da mafi kyawun diyya ga masu ciwon sukari fiye da guda. Ana lasafta allurai dabam. Don insulin safe - akan sukari mai azumi yau da kullun, don maraice - dangane da dabi'un darensa.

Tare da nau'in ciwon sukari na 2 da guda biyu da na biyu mulki mai yiwuwa ne. Nazarin ya nuna cewa a farkon farawar insulin, allura guda ɗaya a rana ya isa don cimma maƙasudin matakin sukari. Gudanarwa na kashi ɗaya ba ya buƙatar karuwa a cikin ƙididdigar kashi. Tare da tsawan ciwon sukari mellitus, tsawon insulin ya fi hankali don gudanar da sau biyu a rana.

Yi amfani da yara

Don ba da izinin yin amfani da Levemir a cikin rukunin jama'a daban-daban, ana buƙatar ɗakunan karatu da suka haɗa da masu sa kai.

Ga yara 'yan kasa da shekaru 2, wannan yana da alaƙa da matsaloli masu yawa, sabili da haka, a cikin umarnin don amfani, akwai iyakokin shekaru. Akwai irin wannan yanayin da sauran dabarun zamani. Duk da wannan, ana amfani da Levemir cikin nasara a cikin jarirai har zuwa shekara guda.

Yin jiyya tare da su yana da nasara kamar yadda yake a cikin manyan yara. A cewar iyaye, babu wani mummunan sakamako.

Sauyawa zuwa Levemir tare da insulin NPH ya zama dole idan:

Yana da muhimmanci sosai: Dakatar da ciyar da mafia na kantin magani koyaushe. Endocrinologists suna sa mu kashe kuɗi akan magungunan ƙwayoyi lokacin da za'a iya daidaita sukarin jini don kawai 147 rubles ... >> >> karanta labarin Alla Viktorovna

  • azumi sukari ne m,
  • ana ganin jinin haila da daddare ko a maraice,
  • yaro ya wuce kima.

Kwatanta Levemir da NPH-insulin

Ba kamar Levemir ba, duk insulin tare da protamine (Protafan, Humulin NPH da analogs) suna da sakamako mafi girma, wanda ke kara haɗarin haɗarin hauhawar jini, tsalle-tsalle na sukari yana faruwa a cikin kullun.

Proven Levemir Amfanin:

  1. Yana da tasiri wanda ake iya faɗi.
  2. Yana rage yiwuwar hauhawar jini: mai tsanani da kashi 69%, cikin dare da 46%.
  3. Yana haifar da ƙarancin nauyi a cikin ciwon sukari na 2: a cikin makonni 26, nauyin a cikin marasa lafiya akan Levemir yana ƙaruwa da kilogram 1.2, kuma a cikin masu ciwon sukari akan NPH-insulin ta 2.8 kg.
  4. Yana daidaita yunwar, wanda ke haifar da raguwar ci a cikin marasa lafiya tare da kiba. Masu ciwon sukari a Levemir suna cinye matsakaita kimanin 160 kcal / rana.
  5. Secreara yawan ɓoyewa na GLP-1. Tare da nau'in ciwon sukari na 2, wannan yana haifar da karuwar mahaɗan insulin nasu.
  6. Yana da tasiri mai kyau akan metabolism-salt salt, wanda ke rage haɗarin hauhawar jini.

Onlyayan ɓarkewar Levemir kawai idan aka kwatanta da shirye-shiryen NPH shine babban farashi. A cikin 'yan shekarun nan, an haɗa shi cikin jerin mahimman magunguna, don haka marasa lafiya masu ciwon sukari na iya samun shi kyauta.

Levemir sabon insulin ne, saboda haka bashi da ilimin tsutsotsi masu saukin tsada. Mafi kusanci a cikin kaddarorin da tsawon lokacin aiki shine kwayoyi daga ƙungiyar dogon insulin analogues - Lantus da Tujeo.

Canzawa zuwa wani insulin yana buƙatar sake dawowa da ƙimar ƙwaƙwalwa kuma babu makawa yana haifar da lalacewa ta ɗan lokaci a cikin biyan bashin mellitus, sabili da haka, dole ne a canza magunguna kawai saboda dalilai na likita, alal misali, tare da rashin haƙuri na mutum.

Don yin karatu: jerin shahararrun dogon kwayar insulin

Umarni na musamman

Jiyya tare da Levemir yana rage haɗarin cututtukan hypoglycemia da dare kuma a lokaci guda ba ya haifar da karuwa mai nauyi. Wannan, bi da bi, yana ba ku damar canza ƙarar mafita, zaɓi gwargwadon da ya dace, haɗa tare da Allunan daga wannan tsari don ingantacciyar iko.

Lokacin da kake shirin doguwar tafiya tare da canjin yankin lokaci, tuntuɓi likitanka.

Tsaya shan da rage kashi an haramta shi sosai don guje wa hypoglycemia.

Cutar bayyanar wani hari sune:

  • jin ƙishirwa
  • gagging
  • tashin zuciya
  • yanayin bacci
  • bushe fata
  • urination akai-akai
  • talaucin abinci
  • lokacin da kuka sha, kuna jin ƙoshin acetone.

Tare da karuwa a cikin kashi, tsallake abinci na tilas, hauhawar da ba'a zata ba, hauhawar jini zai iya haɓaka. Kulawa mai zurfi yana daidaita yanayin.

Kamuwa da jiki yana haifar da karuwa a cikin yawan insulin. A cikin cututtukan glandar thyroid, koda da hanta, ana kuma yin gyare-gyaren kashi.

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Magani na Ciwon ciki1 ml
abu mai aiki:
insulin ya lalataCIGABA 100 (14.2 MG)
magabata: glycerol, phenol, metacresol, zinc (kamar zinc acetate), sinadarin hydrogen phosphate dihydrate, chloride sodium, hydrochloric acid ko sodium hydroxide, ruwa don yin allura
Alkalami guda 1 ya ƙunshi 3 ml na bayani daidai 300 PIECES
1 na insulin detemir yana dauke da 0.142 mg na insulin-gishiri a jiki, wanda yayi daidai da raka'a 1 na insulin mutum (IU)

Levemir ko Lantus - wanda yafi kyau

Maƙerin ya bayyana fa'idodin Levemir idan aka kwatanta da babban mai fafatawarsa - Lantus, wanda ya ba da farin ciki a cikin umarnin:

  • aikin insulin ya fi dindindin
  • miyagun ƙwayoyi yana ba da ƙarancin nauyi.

Dangane da sake dubawa, waɗannan bambance-bambancen ba su da kusan ganuwa, don haka marasa lafiya sun fi son magani, takardar sayen magani don wanda ya fi sauƙi a cikin wannan yankin.

Babban bambanci mai mahimmanci yana da mahimmanci ga marasa lafiya waɗanda ke narke insulin: Levemir ya haɗu da ruwan gishiri sosai, Lantus kuma ya rasa dukiyar sa lokacin da aka lalata shi.

Ciki da Levemir

Levemir baya tasiri kan ci gaban tayinSaboda haka, ana iya amfani da shi ta hanyar mata masu juna biyu, ciki har da waɗanda ke da ciwon sukari. Yawan maganin a lokacin daukar ciki yana buƙatar daidaitawa akai-akai, kuma ya kamata a zaɓi tare tare da likita.

A cikin nau'in 1 na ciwon sukari, marasa lafiya a cikin lokacin haihuwar yaro suna kasancewa a kan tsawon wannan insulin ɗin da suka karɓa a baya, kawai canjin sa zai canza. Sauyawa daga magungunan NPH zuwa Levemir ko Lantus ba lallai bane idan sukari ya zama al'ada.

Tare da ciwon sukari na gestational, a wasu lokuta yana yiwuwa a cimma daidaitaccen ƙwayar cuta ba tare da insulin ba, musamman game da abinci da ilimin jiki. Idan sukari yana yawan haɓaka, ana buƙatar maganin insulin don hana fetopathy a cikin tayin da ketoacidosis a cikin uwa.

Mafi yawan nazarin masu haƙuri game da Levemir suna da kyau. Baya ga haɓaka sarrafa glycemic, marasa lafiya suna lura da sauƙin amfani, kyakkyawan haƙuri, kyawawan ingancin kwalabe da alƙalami, allurai na bakin ciki waɗanda ke ba ku damar yin allurar marasa ciwo. Yawancin masu ciwon sukari suna da'awar cewa hypoglycemia a kan wannan insulin ba shi da m kuma mara ƙarfi.

Nazarin ra'ayoyi mara wuya ne. Sun fito ne daga iyayen jarirai masu ciwon sukari da kuma mata masu ciwon suga.

Waɗannan marasa lafiya suna buƙatar rage allurai na insulin, don haka Levemir Flexpen ba shi da matsala a gare su.

Idan babu wani madadin, kuma kawai irin wannan magani za'a iya samu, masu ciwon sukari dole su fasa katuwar katako daga alƙawarin da za'a iya jefa shi kuma a sake haɗa su cikin wani ko kuma yin allura tare da sirinji.

Aikin Levemir yana da ban mamaki Ya fi damuwa makonni 6 bayan buɗewa. Marasa lafiya tare da ƙarancin insulin na tsawon lokaci ba su da lokacin da za su kashe raka'a 300 na miyagun ƙwayoyi, don haka dole ne a zubar da ragowar.

Da fatan za a kula: Shin kuna mafarki don kawar da ciwon sukari sau ɗaya kuma? Koyi yadda ake shawo kan cutar, ba tare da amfani da magunguna masu tsada ba, amfani kawai ... >> kara karantawa anan

Levemir: umarnin don amfani, farashi, sake dubawa da kuma amfani da analogues

"Levemir" magani ne na warkewa wanda aka yi amfani da shi bisa umarnin da aka yi amfani da shi don daidaita matakan insulin, ba tare da la'akari da adadin abincin da aka ɗauka da fasalin kayan abinci ba.

Sau da yawa likitocin suna ba da shawarar wannan magani ga marassa lafiyar su rage sukarin jininsu.

Abubuwan da ke aiki a cikin kayan sunadarai da kaddarorin suna kama da insulin, wanda aka samar a jikin mutum.

Haihuwa da lactation

Babu matsala a ɗauki Levemir lokacin ɗaukar jariri, an tabbatar da wannan ta hanyar bincike. Insulin baya cutar tayin da mahaifiyar kanta da kwatancen da aka za6a. Ba jaraba bane. Idan ba a kula da ciwon sukari ba yayin wannan lokacin, wannan yana haifar da manyan matsaloli. Lokacin ciyarwa, ana sake daidaita sashin ɗin.

A cikin farkon farkon, bukatar insulin na iya raguwa, a cikin na biyu da na ukun yana jin daɗa kaɗan. Bayan bayarwa, matakin bukatar ya zama iri daya kamar kafin daukar ciki.

Yi amfani da ƙuruciya da tsufa

Ga yara, yawan lissafin insulin ana lissafta shi ne gwargwadon abincin da suke bi. Idan akwai abinci mai yawa tare da karancin abubuwan carbohydrate a cikin abincin, to maganin zai zama ragu. Tare da sanyi da mura, sashi zai buƙaci ƙara sau 1.5-2.

A cikin tsofaffi, ana kula da sukari na jini sosai. Ana kirga kashi a tsanaki daban-daban, musamman ga wadanda ke fama da cututtukan koda da hanta. Magungunan magunguna a cikin marasa lafiya matasa da tsofaffi ba su da bambanci.

Sharuɗɗan da yanayin ajiya

Adana ƙwayoyi a cikin firiji a 2-8 ° C. Ba a buƙatar sirinjin da kansa don sanyaya. Tare da abubuwanda ke ciki na katako, ana iya adana shi tsawon wata daya da rabi a zazzabi a dakin. Kafar tana taimakawa kare abin da ke cikin sirinji daga haskoki na haske. Magungunan sun dace don amfani a cikin watanni 30 daga ranar da aka sake su. Ana sake shi ne kawai ta takardar sayan magani.

Zaka iya tsaftace alkairin sirinji tare da auduga a ciki a cikin maganin barasa. An haramta shiga cikin ruwa da faduwa. Idan saukar, hannun na iya lalacewa kuma abin da ke ciki zai kife.

Kwatanta tare da analogues

MagungunaAmfaninRashin daidaitoFarashin, rub.
LantusYana da sakamako mai tsawo - sabon nasara a lura da ciwon sukari. Yana yin aiki da ƙarfi, ba tare da kololuwa ba. Idan kwai yana buƙatar shigar da yawan insulin, yana da kyau ka zaɓi wannan zaɓi.An yi imanin cewa miyagun ƙwayoyi suna kara saurin kamuwa da cutar kansa idan aka kwatanta da sauran analogues. Amma ba a tabbatar da wannan ba.Daga 1800
TujeoYana rage haɗarin cutar hawan jini, musamman da dare. Sabuwar kwayar insulin ta Sanofi ya kara samun ci gaba. Ingantacce har zuwa 35 hours. Inganci don sarrafa glycemic.Ba za a iya amfani dashi don maganin cutar ketoacidosis mai ciwon sukari ba. Abu ne wanda ba a ke so a dauki yara da mata masu juna biyu. Ba tare da cututtukan da kodan da hanta ba, ba a sanya shi ba .. Abubuwan da za a iya yi wa glargine zai yiwuDaga 2200
ProtafanYana da tasirin matsakaici. An wajabta wa masu ciwon sukari a cikin mata masu juna biyu. Ya dace da T1DM da T2DM. Yana tallafawa matakan glucose na jini da kyau.Zai iya haifar da itching a kan fata, redness, busa.Daga 800
RosinsulinAmintacce don lactation da ciki. Ana samar da nau'ikan guda uku (P, C da M), waɗanda aka rarrabe su da sauri da tsawon lokacin fallasa.Bai dace da kowa ba, duka sun dogara ne da halaye na mutum.Daga 1100
TresibaBabban abu shine insulin degludec. Da mahimmanci yana rage aukuwar cututtukan jini. Yana kula da matakan glucose mai ƙarfi a cikin yini. Ingantacce na fiye da awanni 40.Bai dace da kula da yara ba, masu shayarwa da mata masu juna biyu. Kadan ne ke aiki a aikace. Sanadin m halayen.Daga 8000.

A cewar masana, idan bayan gudanar da kashi daya na insulin babu wani ci gaba a cikin sarrafawar sukari, zai zama da buqatar a kirkiri analog na takaitaccen aiki.

Levemir yana da kyau kwarai don kula da marasa lafiya da masu cutar siga. Wannan kayan aiki na zamani wanda aka tabbatar zai taimaka wajen daidaita matakan glucose na jini.

Irina, shekara 27, Moscow.

“Da farko dai, na ki yarda in tsayar da Levemir. Wanene yake so ya sami ƙwayar insulin ko ƙara nauyi? Likita ya tabbatar min cewa ba zai yiwu a murmure daga gareshi ba kuma bai haifar da dogaro ba. An umurce ni da raka'a 6 na insulin sau ɗaya a rana.

Amma damuwar ba ta watse ba.Shin zan iya ɗaukar kyakkyawan yaro, shin akwai matsaloli tare da haɓakarsa? Magungunan suna da tsada. Ban lura da wani illa ba a gida; an haife yaron lafiya. Bayan na haihu, sai na daina allurar Levemir; babu cutar cirewar.

Don haka ina ba da shawarar shi. ”

Eugene, dan shekara 43, Moscow.

“Ina da nau'in ciwon sukari na 1 tun lokacin balaga. A baya can, ya wajaba don tara insulin a cikin sirinji daga ampoules, auna raka'a kuma allurar da kanka. Sirinjin zamani tare da kayan kwalliyar insulin sunfi dacewa, suna da ƙwanƙwasa don saita adadin raka'a. Magungunan suna aiki bisa ga umarnin, Na ɗauke shi tare da ni a kan tafiye-tafiye na kasuwanci, komai ya wuce kima. Ina ba ku shawara. ”

Huseyn, shekara 40, Moscow.

“Da dadewa na kasa magance matsalar sukari da safe. Ya juya zuwa Levemir. Rarrabawa cikin allura 4, wanda nayi a cikin awanni 24. Ina biye da karancin abinci mai abin carb. Wata daya bayan miƙa mulki ga sabon tsarin mulki, sukari baya sake tashi. Godiya ga masana'antun. ”

Levemir Flexpen da Penfil - umarnin don amfani, analogues, sake dubawa

Levemir magani ne mai haɓaka da kwayar halitta wanda yake daidai yake a cikin tsarin sunadarai da aiki zuwa insulin ɗan adam. Wannan magani yana cikin rukunin insulin na ɗan adam mai aiki da dogon lokaci.

Levemir Flexpen ne na musamman game da alkalami na insulin tare da fesa. Godiya gareshi, ana iya gudanar da insulin daga rukunin 1 zuwa raka'a 60. Za'a iya samun daidaituwa na cikin zafin jiki a cikin raka'a ɗaya.

A kan shelf na kantin magunguna zaka iya samun Levemir Penfill da Levemir Flekspen. Ta yaya suka banbanta da juna? Dukkanin abubuwan da aka tsara da kashi, hanyar gudanarwa iri daya ne. Bambanci tsakanin wakilan yana kan hanyar sakin. Levemir Penfill akwati ne mai maye gurbin wanda za'a iya warware alkalami. Kuma Levemir Flekspen shine alkalami mai sikirin da za'a iya zubar dashi tare da ginanniyar katako a ciki.

Ana amfani da Levemir don kula da matakan insulin na jini na basal, ba tare da la'akari da abinci ba.

Babban kayan aiki na miyagun ƙwayoyi shine insulin detemir. Wani insulin ne na ɗan adam wanda aka kera shi ta amfani da lambar ƙwayar halittar ƙwayar ƙwayar ƙwayar cuta ta Saccharomyces cerevisiae. Adadin abu mai aiki a cikin 1 ml na maganin shine 100 IU ko 14.2 mg. Haka kuma, 1 na ragin insulin na Levemir yayi daidai da naúrar 1 na insulin na mutum.

Componentsarin abubuwan da aka gyara suna da tasirin taimako. Kowane bangare yana da alhakin wasu ayyuka. Suna daidaita tsarin mafita, suna ba da alamun inganci na musamman ga miyagun ƙwayoyi, kuma suna tsawaita lokacin ajiya da rayuwar rayuwa.

Hakanan, waɗannan abubuwa suna taimakawa ga daidaitawa da haɓaka magunguna da magunguna na babban aikin mai aiki: suna inganta bioavailability, ƙanshin nama, rage ɗaukar nauyin sunadarai na jini, sarrafa metabolism da sauran hanyoyin kawar da kai.

An hada waɗannan ƙarin abubuwa masu zuwa cikin maganin magani:

  • Glycerol - 16 MG,
  • Metacresol - 2.06 mg,
  • Zinc acetate - 65,4 mcg,
  • Phenol - 1.8 MG
  • Sodium Chloride - 1.17 mg
  • Hydrochloric acid - q.s.,
  • Hydrophosphate dihydrate - 0.89 mg,
  • Ruwa don allura - har zuwa 1 ml.

Kowane alkalami ko kadi sun ƙunshi 3 ml na bayani ko 300 IU na insulin.

Pharmacodynamics

Levemir insulin shine kwatancen insulin na ɗan adam tare da bayanan mai amfani, mai laushi. Ayyukan nau'in jinkirta yana faruwa ne sakamakon babban haɗin gwiwa mai tasiri na kwayoyin ƙwayoyi.

Sun kuma ɗaura ƙarin don sunadarai a yankin sarkar sashi. Duk wannan yana faruwa a wurin allura, saboda haka insulin detemir ya shiga cikin jini a hankali.

Kuma ƙwayoyin da aka yi niyya suna karɓar kashi na yau da kullun dangane da sauran wakilan insulin.

Wadannan hanyoyin aiwatarwa suna da tasirin aiki wajen rarraba magungunan, wanda ke samar da karin karbuwa da bayanin tsarin metabolism.

Matsakaicin da aka ba da shawarar 0.2-0.4 U / kg ya kai rabin ƙarfin tasiri bayan sa'o'i 3.A wasu halayen, ana iya jinkirta wannan lokacin har zuwa awanni 14.

Manuniya da contraindications

Iyakar abin da kawai ke nuna amfanin Levemir shine bayyanar cutar sikari ta-insulin-insulin-a cikin manya da yara kanana shekaru 2.

Raarfafa magunguna don amfanin miyagun ƙwayoyi shine kasancewar rashin haƙuri na mutum zuwa babban abu mai aiki da abubuwan taimako.

Hakanan, ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa tana cikin ƙananan yara a cikin shekaru 2 saboda ƙarancin karatun asibiti a wannan rukuni na marasa lafiya.

Levemir: umarnin don amfani. Yadda za a zabi kashi. Nasiha

Insulin Levemir (detemir): koya duk abin da kuke buƙata. A ƙasa zaku sami cikakken umarni don amfani da aka rubuta cikin harshe mai amfani. Gano:

Levemir insulin (basal) ne wanda yakasance, wanda kamfanin shahararren daraja na duniya Novo Nordisk ke samarwa. Anyi amfani da wannan magani tun tsakiyar 2000s. Ya gudanar da samun shahara tsakanin masu ciwon sukari, kodayake insulin Lantus yana da kasada mai girma na kasuwa. Karanta ainihin sake dubawa na marasa lafiya da ke da nau'in 2 da nau'in ciwon sukari na 2, da kuma abubuwan amfani da yara.

Hakanan koya game da jiyya masu tasiri waɗanda ke sa sukarin jini 3.9-5.5 mmol / L barga 24 a rana, kamar yadda yake a cikin mutane masu lafiya. Tsarin Dr. Bernstein, wanda yake rayuwa tare da ciwon sukari sama da shekaru 70, yana bawa manya da yara masu ciwon sukari damar kare kansu daga rikice rikice.

Dogon insulin levemir: cikakken labarin

An ba da kulawa ta musamman don sarrafa ciwon sukari. Levemir shine magani na zabi ga mata masu juna biyu wadanda ke da yawan jini. Binciken bincike mai zurfi ya tabbatar da amincinsa da tasiri ga mata masu juna biyu, da kuma ga yara daga shekaru 2.

Ka tuna fa cewa insulin insulin ya ragu sosai kamar sabo. Ba za a iya tantance ingancin miyagun ƙwayoyi ta bayyanarsa ba. Sabili da haka, bai cancanci siyan Levemir na hannu ba, ta hanyar sanarwa. Sayi shi a cikin manyan shagunan sanannun ma'aikata waɗanda ma'aikatansu sun san ka'idodin adana kuma basu da saurin cika su.

Shin, ana iya samarda insulin a ciki? Dogo ne ko gajeru?

Levemir insulin aiki ne mai dadewa. Kowane kashi ana sarrafa lowers sukari na jini a cikin awanni 18 zuwa 24. Koyaya, masu ciwon sukari da ke bin tsarin karas-carb na buƙatar ƙarancin allurai, sau 2-8 ƙasa da na misali.

Lokacin amfani da irin waɗannan sigogin, sakamakon maganin yana ƙare da sauri, a cikin awanni 10-16. Ba kamar matsakaiciyar insulin na Protafan ba, Levemir bashi da ƙudurin magana da aka ambata.

Kula da sabon magani na Tresib, wanda ya fi tsayi, har zuwa awanni 42, kuma mafi inganci.

Levemir ba gajeran insulin bane. Bai dace da yanayi inda ake buƙatar saukar da sukari da sauri ba. Hakanan, bai kamata a sanya shi abinci kafin abinci don rage abincin da mai ciwon sukari yake shirin ci ba. Don waɗannan dalilai, ana amfani da shirye-shiryen gajere ko ultrashort. Karanta labarin “Nau'in Insulin da Tasirinsu” daki-daki daki daki.

Kalli bidiyon Dr. Bernstein. Gano dalilin da ya sa Levemir ya fi Lantus kyau. Fahimci sau nawa a rana kuna buƙatar farashin shi kuma a wani lokaci. Bincika cewa kuna adana insulin kuli-kuli don kada ya lalace.

Yadda za a zabi kashi?

Yawan Levemir da sauran nau'ikan insulin dole ne a zabi su daban-daban. Ga masu ciwon sukari na manya, akwai ingantacciyar shawarar da za a fara da 10 KUDI ko 0.1-0.2 LATSA / kg.

Koyaya, ga marasa lafiya da ke bin abincin karam, wannan kashi zai yi yawa. Lura da sukarin jininka tsawon kwanaki. Zaɓi mafi kyau sashi na insulin ta amfani da bayanan da aka karɓa.

Karanta karin bayani a cikin labarin "Lissafin allurai na dogon insulin don allurar cikin dare da safe."

Nawa ne amfanin wannan maganin don shigar da shi cikin yaro mai shekaru 3?

Ya dogara da irin nau'in abincin da yaro mai ciwon sukari yake bi.Idan an canza shi zuwa abincin abinci mai ƙanƙantarwar abinci, to, allurai kaɗan, kamar dai homeopathic, za'a buƙaci hakan.

Wataƙila, kuna buƙatar shiga Levemir da safe da maraice a allurai waɗanda basu wuce 1 raka'a ba. Kuna iya farawa da raka'a 0.25. Don yin daidai da irin waɗannan allurai kaɗan, yana da mahimmanci don tsarmar maganin masana'antar don yin allura.

Karanta ƙarin game da shi anan.

A lokacin sanyi, guban abinci da sauran cututtukan cututtuka, ya kamata a kara yawan insulin kimanin sau 1.5. Lura cewa shirye-shiryen Lantus, Tujeo da Tresiba ba za a iya gurbata su ba.

Saboda haka, ga ƙananan yara na nau'ikan insulin, kawai Levemir da Protafan suna saura. Yi nazarin labarin "Ciwon sukari a cikin Yara."

Koyi yadda za ku fadada lokacin tafiyar ku kuma ku tabbatar da kyakkyawan ikon sarrafa glucose na yau da kullun.

Ilimin insulin: yadda ake zaba kwayoyi Long insulin don injections da daddare da safe Kuyi lissafin kashi na insulin azumi kafin abinci Insulin na insulin: inda kuma yadda ake yin allura

Ta yaya za a tsayar da Levemir? Sau nawa a rana?

Levemir bai isa ya saka farashi sau ɗaya a rana ba. Dole ne a gudanar dashi sau biyu a rana - safe da dare. Haka kuma, aikin kashi na maraice yawanci bai isa ba duk daren. Saboda wannan, masu ciwon sukari na iya samun matsaloli tare da glucose da safe a kan komai a ciki. Karanta labarin "Sugar a kan komai a ciki da safe: yadda za a dawo da shi al'ada". Hakanan bincika kayan "Inulin insulin: ina kuma yadda ake yin allura".

Shin za a iya kwatanta wannan magani da Protafan?

Levemir ya fi Protafan kyau. Abubuwan insulin na protafan ba su tsawan tsayi, musamman idan allurai basu da yawa. Wannan magani ya ƙunshi furotin furotin na dabba, wanda yawanci yakan haifar da rashin lafiyan halayen.

Zai fi kyau ki ƙi amfani da insulin protafan. Ko da an ba da wannan magani kyauta, kuma sauran nau'ikan insulin masu aiki da tsayi za a sayo su da kuɗi. Je zuwa Levemir, Lantus ko Tresiba.

Karanta karin bayani a labarin “iri irin insulin da Tasirinsu”.

Levemir Penfill da Flekspen: Menene Banbancin?

Flekspen sune allon alkalami wanda aka sa kwalliya a jikin katako wanda aka kera Levemir.

Penfill magani ne na Levemir wanda ake siyarwa ba tare da ƙyamar sirinji don haka zaka iya amfani da sirinjin insulin na yau da kullun. Fensspen alkalami yana da sashi na 1 na sashi.

Wannan na iya zama da wahala cikin lura da ciwon sukari a cikin yaran da ke buƙatar karancin allurai. A irin waɗannan halayen, yana da kyau a samo kuma amfani da Penfill.

Levemir bashi da alamun analogues mai arha. Saboda tsari yana kiyaye shi ta wani lamuni wanda ingancinsa bai ƙare ba. Akwai nau'ikan nau'ikan insulin na dogon lokaci daga wasu masana'antun. Waɗannan magungunan Lantus, Tujeo da Tresiba ne.

Kuna iya nazarin cikakkun labarai game da kowannensu. Koyaya, duk waɗannan magungunan ba su da arha. Matsakaici na tsawon lokaci, irin su Protafan, sun fi araha. Koyaya, yana da mahimmancin halayen saboda wanda Dr. Bernstein da kuma shafin yanar gizon haƙuri na endocrin.

com baya bada shawarar amfani da shi.

Levemir ko Lantus: wane insulin ne ya fi kyau?

An ba da cikakken amsar wannan tambaya a cikin labarin akan insulin Lantus. Idan Levemir ko Lantus sun dace da ku, to ku ci gaba da amfani da shi. Kada ku canza magani ɗaya zuwa wani sai dai idan takan zama dole.

Idan kuna shirin fara allurar dogon insulin ne, to sai a fara Levemir da farko. Sabuwar insulin ta Treshiba ta fi Levemir da Lantus kyau, saboda yana dadewa kuma ya yi laushi sosai.

Koyaya, yana da kusan kusan sau 3 mafi tsada.

Levemir yayin daukar ciki

An gudanar da babban binciken asibiti wanda ya tabbatar da aminci da tasiri na gudanarwar Levemir yayin daukar ciki.

Tsarin insulin nau'ikan Lantus, Tujeo da Tresiba ba zasu iya yin alfahari da wannan tabbataccen shaidar amincin su ba.

A ba da shawarar mace mai juna biyu da ke da yawan sukari mai jini sosai ta fahimci yadda ake lissafin allurai da suka dace.

Insulin bashi da hadari ko dai ga mahaifiyar ko kuma tayi, idan har aka zaɓi sashi. Cutar sankarar mahaifa, idan ba a kula da ita ba, na iya haifar da manyan matsaloli. Sabili da haka, yi ƙarfin zuciya da allurar Levemir idan likita ya umurce ku da yin hakan. Yi ƙoƙarin yin ba tare da maganin insulin ba, bin ingantaccen tsarin abinci. Karanta labaran "Cutar Cutar Ciki" da "Ciwon Cutar na ciki" don ƙarin bayani.

An yi amfani da Levemir don sarrafa nau'in 2 da nau'in 1 na ciwon sukari tun daga tsakiyar 2000s. Kodayake wannan maganin yana da ƙarancin magoya baya fiye da Lantus, isassun sake dubawa sun tara tsawon shekaru. Mafi yawansu suna da inganci. Marasa lafiya lura cewa insulin detemir da kyau lowers jini sukari. A lokaci guda, haɗarin ciwo mai ƙarfi yana ragu sosai.

Matan da suka yi amfani da Levemir a lokacin da suke cikin ciki sun rubuto yawancin abubuwan da aka sake duba su ne don magance ciwon sikari. Ainihin, waɗannan marasa lafiya sun gamsu da maganin. Ba jaraba bane, bayan an haihuwar allura na haihuwa ba tare da matsaloli ba. Ana buƙatar daidaituwa don kada kuyi kuskure tare da sashi, amma tare da sauran shirye-shiryen insulin daidai yake.

A cewar marasa lafiya, babban koma-bayan shi ne cewa dole ne a yi amfani da katun a cikin kwanaki 30. Wannan ya yi guntu da wani lokaci. Yawancin lokaci dole ne ku zubar da manyan ma'aunan da ba a amfani da su ba, kuma bayan duk abin, an biya musu kuɗi. Amma duk magunguna masu gasa suna da matsala iri ɗaya. Nazarin masu ciwon sukari sun tabbatar da cewa Levemir ya fi matsakaicin matsakaiciyar insulin Protafan ta kowane fannoni muhimmanci.

Insulin LEVEMIR: sake dubawa, umarni, farashi

Levemir Flexpen kwatanci ne na insulin ɗan adam kuma yana da tasirin hypoglycemic. Levemir an samar dashi ne ta hanyar karin kwayar halitta ta sake amfani da DNA ta amfani da cerechaiae Saccharomyces.

Yana da kwaskwarimar ma'anar insulin na ɗan adam tare da tasiri na tsawan lokaci da yanayin ɗakin kwana wanda yake da ƙima, idan aka kwatanta shi da insulin glargine da isofan-insulin.

Tsawancin wannan maganin yana faruwa ne sakamakon cewa kwayoyin detemir insulin suna da ikon yin tarayya da su a wurin allurar, sannan kuma sun daure wa albumin ta hanyar hada su da sashin kiba mai kiba.

Insulin na Detemir ya kai gaɓoɓin ƙwaƙwalwar mahaifa a hankali fiye da isofan-insulin. Wannan haɗin na jinkirin kayan aikin jinkiri yana ba da damar furofayil ɗin ɗaukar hoto da aikin Levemir Penfill fiye da isofan-insulin.

Lokacin da aka ɗaura takamaiman masu karɓa a kan membrane na cytoplasmic na insulin, insulin ya samar da hadaddun ƙira na musamman wanda ke ƙarfafa haɗarin enzymes masu mahimmanci a cikin sel, irin su hexokinase, glycogen synthetase, pyruvate kinase da sauransu.

Babban nuni ga amfanin Levemir Flexpen shine ciwon sukari.

Contraindications

  1. Rashin yarda da babban da ƙarin kayan aikin abu mai aiki.
  2. Shekaru biyu zuwa shekaru biyu.

Umarnin don amfani (sashi)

Tsawon lokacin bayyanuwa ga miyagun ƙwayoyi ya dogara da sashi. A farkon jiyya ya kamata a saka farashi sau ɗaya a rana, zai fi dacewa a kan Hauwa ta abincin dare ko kafin lokacin kwanta barci. Ga marasa lafiya waɗanda ba su sami insulin a baya ba, sashin farko shine raka'a 10 ko raka'a 0.1-0.2 a kowace kilogiram na nauyin jiki na al'ada.

Ga marasa lafiya waɗanda suka daɗe suna amfani da wakilai na hypoglycemic, likitoci suna ba da shawarar kashi 0.2 zuwa 0.4 a kowace kilogiram na nauyin jiki. Ayyukan yana farawa bayan sa'o'i 3-4, wani lokacin har zuwa 14 hours.

Ana amfani da kashi na yau da kullun sau 1-2 a rana. Zaka iya shigar da cikakken kashi nan take sau ɗaya ko raba shi zuwa allurai biyu. A cikin magana ta biyu, ana amfani da miyagun ƙwayoyi da safe da maraice, tazara tsakanin gwamnoni ya zama 12 hours. Lokacin canzawa daga wani nau'in insulin zuwa Levemir, kashi na maganin yana canzawa.

Ana yin lissafin sashi ne ta hanyar endocrinologist bisa ga alamomi masu zuwa:

  • digiri na aiki
  • fasalin abinci mai gina jiki
  • matakin sukari
  • tsananin cutar Patho,
  • ayyukan yau da kullun
  • gaban concomitant cututtuka.

Za'a iya canza warkaswa idan tiyata ta zama tilas.

Side effects

Har zuwa 10% na marasa lafiya suna ba da rahoton sakamako masu illa yayin shan maganin. A cikin rabin shari'o'in, wannan hypoglycemia ne. Sauran tasirin bayan gudanarwa ana nuna su ta hanyar kumburi, redness, zafi, itching, kumburi. Jinya na iya faruwa. Abubuwan da ba su dace ba yakan ɓace bayan weeksan makonni.

Wani lokacin yanayin yana ƙaruwa saboda haɓakar ciwon sukari, takamaiman amsa yana faruwa: ciwon sukari da ciwon mara mai ƙonewa da rashin jin daɗi. Dalilin wannan shine don kula da matakan glucose mafi kyau da kuma sarrafa glycemia. Jikin yana sake tsarawa, kuma lokacin da ya dace da maganin, alamomin basa tafiya da kansu.

Daga cikin mawuyacin halayen, mafi yawan su ne:

  • malfunctioning na tsakiya juyayi tsarin (ƙarar jin zafin ji, ƙarancin na ƙarshen, ƙarancin gani acuity da tsinkaye haske, tingling ko kona ji)
  • rikice-rikice na carbohydrate metabolism (hypoglycemia),
  • urticaria, itching, rashin lafiyan, tashin hankalin anaphylactic,
  • na ciki edema
  • pathology na adipose nama, yana haifar da canji a jikin mutum.

Dukkansu suna fuskantar gyara ta amfani da kwayoyi. Idan wannan bai taimaka ba, likitan ya maye gurbin maganin.

Yawan damuwa

Yawan magungunan da zai tsokani wannan hoton na asibiti, kwararru ba su kafa su ba. Tsarin allurai na yau da kullun na iya haifar da yawan kumburi. Harin yana farawa mafi yawan lokuta a cikin dare ko a cikin matsi.

Za'a iya kawar da mai saukin kai da kanka: ku ci cakulan, yanki na sukari ko samfurin da ke da ƙwayar carbohydrate. Wani nau'i mai tsanani, lokacin da mai haƙuri ya rasa hankali, ya ƙunshi gudanarwar ƙwayar cuta zuwa har zuwa 1 mg na glucagon / glucose bayani a cikin jijiya. Wannan kwararren likita ne kaɗai zai iya yin wannan. Idan hankali bai koma ga mutum ba, ana gudanar da glucose bugu da .ari.

Hulɗa da ƙwayoyi

An yi nasarar amfani da Levemir a hade tare da sauran magunguna: jami'in hypoglycemic a cikin nau'ikan allunan ko gajeren insulins. Koyaya, ba a so a gauraya nau'ikan insulin a cikin sirinji iri ɗaya.

Yin amfani da wasu kwayoyi yana canza mai nuna alamun bukatun insulin. Don haka, wakilai na hypoglycemic, anhydrase carbonic, inhibitors, oxidases monoamine da sauransu suna haɓaka aikin abu mai aiki.

Hormones, hana haihuwa, kwayoyi dauke da aidin, magungunan hana haihuwa, danazole sun sami damar raunana tasirin.

Salicylates, octreotide, da reserpine zasu iya yin ƙasa da haɓaka da buƙatar insulin, kuma beta-blockers suna rufe alamun bayyanar cututtuka na hypoglycemia, da hana daidaituwa na matakan sukari.

Abubuwan haɗuwa tare da ginin sulfite ko thiol, kazalika da nau'in maganin jiko, suna da sakamako mai lalacewa.

Amfani da barasa

Abin sha mai ɗauke da giya na iya tsawaitawa ko haɓaka tasirin hypoglycemic na shiri na insulin, amma yakamata a sha giya tare da masu cutar siga tare da taka tsantsan, tunda yana shafar metabolism a cikin jiki.

Umarni na musamman

Jiyya tare da Levemir yana rage haɗarin cututtukan hypoglycemia da dare kuma a lokaci guda ba ya haifar da karuwa mai nauyi. Wannan, bi da bi, yana ba ku damar canza ƙarar mafita, zaɓi gwargwadon da ya dace, haɗa tare da Allunan daga wannan tsari don ingantacciyar iko.

Lokacin da kake shirin doguwar tafiya tare da canjin yankin lokaci, tuntuɓi likitanka.

Cutar bayyanar wani hari sune:

  • jin ƙishirwa
  • gagging
  • tashin zuciya
  • yanayin bacci
  • bushe fata
  • urination akai-akai
  • talaucin abinci
  • lokacin da kuka sha, kuna jin ƙoshin acetone.

Tare da karuwa a cikin kashi, tsallake abinci na tilas, hauhawar da ba'a zata ba, hauhawar jini zai iya haɓaka. Kulawa mai zurfi yana daidaita yanayin.

Kamuwa da jiki yana haifar da karuwa a cikin yawan insulin. A cikin cututtukan glandar thyroid, koda da hanta, ana kuma yin gyare-gyaren kashi.

Haihuwa da lactation

Babu matsala a ɗauki Levemir lokacin ɗaukar jariri, an tabbatar da wannan ta hanyar bincike. Insulin baya cutar tayin da mahaifiyar kanta da kwatancen da aka za6a. Ba jaraba bane. Idan ba a kula da ciwon sukari ba yayin wannan lokacin, wannan yana haifar da manyan matsaloli. Lokacin ciyarwa, ana sake daidaita sashin ɗin.

A cikin farkon farkon, bukatar insulin na iya raguwa, a cikin na biyu da na ukun yana jin daɗa kaɗan. Bayan bayarwa, matakin bukatar ya zama iri daya kamar kafin daukar ciki.

Yi amfani da ƙuruciya da tsufa

Ga yara, yawan lissafin insulin ana lissafta shi ne gwargwadon abincin da suke bi. Idan akwai abinci mai yawa tare da karancin abubuwan carbohydrate a cikin abincin, to maganin zai zama ragu. Tare da sanyi da mura, sashi zai buƙaci ƙara sau 1.5-2.

A cikin tsofaffi, ana kula da sukari na jini sosai. Ana kirga kashi a tsanaki daban-daban, musamman ga wadanda ke fama da cututtukan koda da hanta. Magungunan magunguna a cikin marasa lafiya matasa da tsofaffi ba su da bambanci.

Sharuɗɗan da yanayin ajiya

Adana ƙwayoyi a cikin firiji a 2-8 ° C. Ba a buƙatar sirinjin da kansa don sanyaya. Tare da abubuwanda ke ciki na katako, ana iya adana shi tsawon wata daya da rabi a zazzabi a dakin. Kafar tana taimakawa kare abin da ke cikin sirinji daga haskoki na haske. Magungunan sun dace don amfani a cikin watanni 30 daga ranar da aka sake su. Ana sake shi ne kawai ta takardar sayan magani.

Zaka iya tsaftace alkairin sirinji tare da auduga a ciki a cikin maganin barasa. An haramta shiga cikin ruwa da faduwa. Idan saukar, hannun na iya lalacewa kuma abin da ke ciki zai kife.

Kwatanta tare da analogues

MagungunaAmfaninRashin daidaitoFarashin, rub.
LantusYana da sakamako mai tsawo - sabon nasara a lura da ciwon sukari. Yana yin aiki da ƙarfi, ba tare da kololuwa ba. Idan kwai yana buƙatar shigar da yawan insulin, yana da kyau ka zaɓi wannan zaɓi.An yi imanin cewa miyagun ƙwayoyi suna kara saurin kamuwa da cutar kansa idan aka kwatanta da sauran analogues. Amma ba a tabbatar da wannan ba.Daga 1800
TujeoYana rage haɗarin cutar hawan jini, musamman da dare. Sabuwar kwayar insulin ta Sanofi ya kara samun ci gaba. Ingantacce har zuwa 35 hours. Inganci don sarrafa glycemic.Ba za a iya amfani dashi don maganin cutar ketoacidosis mai ciwon sukari ba. Abu ne wanda ba a ke so a dauki yara da mata masu juna biyu. Ba tare da cututtukan da kodan da hanta ba, ba a sanya shi ba .. Abubuwan da za a iya yi wa glargine zai yiwuDaga 2200
ProtafanYana da tasirin matsakaici. An wajabta wa masu ciwon sukari a cikin mata masu juna biyu. Ya dace da T1DM da T2DM. Yana tallafawa matakan glucose na jini da kyau.Zai iya haifar da itching a kan fata, redness, busa.Daga 800
RosinsulinAmintacce don lactation da ciki. Ana samar da nau'ikan guda uku (P, C da M), waɗanda aka rarrabe su da sauri da tsawon lokacin fallasa.Bai dace da kowa ba, duka sun dogara ne da halaye na mutum.Daga 1100
TresibaBabban abu shine insulin degludec. Da mahimmanci yana rage aukuwar cututtukan jini. Yana kula da matakan glucose mai ƙarfi a cikin yini. Ingantacce na fiye da awanni 40.Bai dace da kula da yara ba, masu shayarwa da mata masu juna biyu. Kadan ne ke aiki a aikace. Sanadin m halayen.Daga 8000.

A cewar masana, idan bayan gudanar da kashi daya na insulin babu wani ci gaba a cikin sarrafawar sukari, zai zama da buqatar a kirkiri analog na takaitaccen aiki.

Levemir yana da kyau kwarai don kula da marasa lafiya da masu cutar siga. Wannan kayan aiki na zamani wanda aka tabbatar zai taimaka wajen daidaita matakan glucose na jini.

Irina, shekara 27, Moscow.

“Da farko dai, na ki yarda in tsayar da Levemir.Wanene yake so ya sami ƙwayar insulin ko ƙara nauyi? Likita ya tabbatar min cewa ba zai yiwu a murmure daga gareshi ba kuma bai haifar da dogaro ba. An umurce ni da raka'a 6 na insulin sau ɗaya a rana.

Amma damuwar ba ta watse ba. Shin zan iya ɗaukar kyakkyawan yaro, shin akwai matsaloli tare da haɓakarsa? Magungunan suna da tsada. Ban lura da wani illa ba a gida; an haife yaron lafiya. Bayan na haihu, sai na daina allurar Levemir; babu cutar cirewar.

Don haka ina ba da shawarar shi. ”

Eugene, dan shekara 43, Moscow.

“Ina da nau'in ciwon sukari na 1 tun lokacin balaga. A baya can, ya wajaba don tara insulin a cikin sirinji daga ampoules, auna raka'a kuma allurar da kanka. Sirinjin zamani tare da kayan kwalliyar insulin sunfi dacewa, suna da ƙwanƙwasa don saita adadin raka'a. Magungunan suna aiki bisa ga umarnin, Na ɗauke shi tare da ni a kan tafiye-tafiye na kasuwanci, komai ya wuce kima. Ina ba ku shawara. ”

Huseyn, shekara 40, Moscow.

“Da dadewa na kasa magance matsalar sukari da safe. Ya juya zuwa Levemir. Rarrabawa cikin allura 4, wanda nayi a cikin awanni 24. Ina biye da karancin abinci mai abin carb. Wata daya bayan miƙa mulki ga sabon tsarin mulki, sukari baya sake tashi. Godiya ga masana'antun. ”

Levemir Flexpen da Penfil - umarnin don amfani, analogues, sake dubawa

Levemir magani ne mai haɓaka da kwayar halitta wanda yake daidai yake a cikin tsarin sunadarai da aiki zuwa insulin ɗan adam. Wannan magani yana cikin rukunin insulin na ɗan adam mai aiki da dogon lokaci.

Levemir Flexpen ne na musamman game da alkalami na insulin tare da fesa. Godiya gareshi, ana iya gudanar da insulin daga rukunin 1 zuwa raka'a 60. Za'a iya samun daidaituwa na cikin zafin jiki a cikin raka'a ɗaya.

A kan shelf na kantin magunguna zaka iya samun Levemir Penfill da Levemir Flekspen. Ta yaya suka banbanta da juna? Dukkanin abubuwan da aka tsara da kashi, hanyar gudanarwa iri daya ne. Bambanci tsakanin wakilan yana kan hanyar sakin. Levemir Penfill akwati ne mai maye gurbin wanda za'a iya warware alkalami. Kuma Levemir Flekspen shine alkalami mai sikirin da za'a iya zubar dashi tare da ginanniyar katako a ciki.

Ana amfani da Levemir don kula da matakan insulin na jini na basal, ba tare da la'akari da abinci ba.

Babban kayan aiki na miyagun ƙwayoyi shine insulin detemir. Wani insulin ne na ɗan adam wanda aka kera shi ta amfani da lambar ƙwayar halittar ƙwayar ƙwayar ƙwayar cuta ta Saccharomyces cerevisiae. Adadin abu mai aiki a cikin 1 ml na maganin shine 100 IU ko 14.2 mg. Haka kuma, 1 na ragin insulin na Levemir yayi daidai da naúrar 1 na insulin na mutum.

Componentsarin abubuwan da aka gyara suna da tasirin taimako. Kowane bangare yana da alhakin wasu ayyuka. Suna daidaita tsarin mafita, suna ba da alamun inganci na musamman ga miyagun ƙwayoyi, kuma suna tsawaita lokacin ajiya da rayuwar rayuwa.

Hakanan, waɗannan abubuwa suna taimakawa ga daidaitawa da haɓaka magunguna da magunguna na babban aikin mai aiki: suna inganta bioavailability, ƙanshin nama, rage ɗaukar nauyin sunadarai na jini, sarrafa metabolism da sauran hanyoyin kawar da kai.

An hada waɗannan ƙarin abubuwa masu zuwa cikin maganin magani:

  • Glycerol - 16 MG,
  • Metacresol - 2.06 mg,
  • Zinc acetate - 65,4 mcg,
  • Phenol - 1.8 MG
  • Sodium Chloride - 1.17 mg
  • Hydrochloric acid - q.s.,
  • Hydrophosphate dihydrate - 0.89 mg,
  • Ruwa don allura - har zuwa 1 ml.

Kowane alkalami ko kadi sun ƙunshi 3 ml na bayani ko 300 IU na insulin.

Pharmacodynamics

Levemir insulin shine kwatancen insulin na ɗan adam tare da bayanan mai amfani, mai laushi. Ayyukan nau'in jinkirta yana faruwa ne sakamakon babban haɗin gwiwa mai tasiri na kwayoyin ƙwayoyi.

Sun kuma ɗaura ƙarin don sunadarai a yankin sarkar sashi. Duk wannan yana faruwa a wurin allura, saboda haka insulin detemir ya shiga cikin jini a hankali.

Kuma ƙwayoyin da aka yi niyya suna karɓar kashi na yau da kullun dangane da sauran wakilan insulin.

Wadannan hanyoyin aiwatarwa suna da tasirin aiki wajen rarraba magungunan, wanda ke samar da karin karbuwa da bayanin tsarin metabolism.

Matsakaicin da aka ba da shawarar 0.2-0.4 U / kg ya kai rabin ƙarfin tasiri bayan sa'o'i 3. A wasu halayen, ana iya jinkirta wannan lokacin har zuwa awanni 14.

Pharmacokinetics

A miyagun ƙwayoyi ya kai yaduwa a cikin jini bayan 6-8 hours bayan gudanarwa.

Ana samun yawan kulawa da magunguna ta hanyar gudanarwa sau biyu a rana kuma yana da kwanciyar hankali bayan allura 3.

Ba kamar sauran insulin na basal ba, bambancin ɗaukar abu da rarrabawa yana da ƙarfi ya dogara da sifofin mutum ɗaya. Hakanan, babu wani dogaro da asalin launin fata da jinsi.

Bincike ya nuna cewa insulin Levemir a zahiri ba ya daure wa garkuwar jiki, kuma mafi yawan magungunan suna yaduwa cikin jini (yawan maida hankali ne a cikin matsakaicin warkewar cutar ya kai 0.1 l / kg). Metabolized insulin a cikin hanta tare da cirewar metabolites marasa aiki.

Rabin-rabi an yanke shi ne ta dogara da lokacin da aka shiga cikin tsarin jini bayan gudanar da aikin karkashin kasa. Kimanin rabin rabin rayuwar dogaro shine 6-7.

Manuniya da contraindications

Iyakar abin da kawai ke nuna amfanin Levemir shine bayyanar cutar sikari ta-insulin-insulin-a cikin manya da yara kanana shekaru 2.

Raarfafa magunguna don amfanin miyagun ƙwayoyi shine kasancewar rashin haƙuri na mutum zuwa babban abu mai aiki da abubuwan taimako.

Hakanan, ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa tana cikin ƙananan yara a cikin shekaru 2 saboda ƙarancin karatun asibiti a wannan rukuni na marasa lafiya.

Umarnin don amfani

Ana daukar Levemir insulin da ya daɗe yana aiki sau 1 ko sau biyu a rana azaman maganin kara karfi na bolus. Haka kuma, ɗayan allurai shine mafi kyawun sarrafawa a maraice kafin lokacin kwanciya ko a lokacin abincin dare. Wannan sake yana hana yiwuwar rashin lafiyar dare.

An zabi allurai ta hanyar likita daban-daban ga kowane mara lafiya. Sashi da mita na gudanarwa ya dogara da aikin mutum, ka'idodin abinci mai gina jiki, matakin glucose, tsananin cutar da kuma tsarin kulawa da marasa lafiya na yau da kullun. Bugu da ƙari, ba za a iya zaɓar magani na asali ba sau ɗaya. Duk wata juyawa a cikin abubuwan da aka ambata a sama ya kamata a sanar da likita, kuma ya kamata a sake yin amfani da maganin yau da kullun.

Hakanan, maganin ƙwayar cuta yana canzawa tare da haɓakar kowane cuta mai haɗari ko buƙatar buƙatar saƙo na tiyata.

Ba'a ba da shawarar canza sashi daban-daban, tsallake shi, daidaita yanayin gudanarwa, saboda haka akwai yuwuwar samun hauhawar cutar hypoglycemic ko hyperglycemic coma da exacerbations na neuropathy da retinopathy.

Ana iya amfani da Levemir azaman maganin monotherapy, kuma haɗe tare da gabatar da gajeren insulins ko magungunan ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta na baka. Akwai cikakken magani, mafi yawan lokutan karbar shine 1 lokaci.

Ainihin kashin shine raka'a 10 ko 0.1 - 0.2 raka'a / kg.

Lokaci na gudanarwa a lokacin ranar yana ƙaddara ne ga mai haƙuri da kansa, kamar yadda ya dace da shi. Amma kowace rana kuna buƙatar allurar miyagun ƙwayoyi a lokaci guda.

Levemir: umarnin don amfani. Yadda za a zabi kashi. Nasiha

Insulin Levemir (detemir): koya duk abin da kuke buƙata. A ƙasa zaku sami cikakken umarni don amfani da aka rubuta cikin harshe mai amfani. Gano:

Levemir insulin (basal) ne wanda yakasance, wanda kamfanin shahararren daraja na duniya Novo Nordisk ke samarwa. Anyi amfani da wannan magani tun tsakiyar 2000s. Ya gudanar da samun shahara tsakanin masu ciwon sukari, kodayake insulin Lantus yana da kasada mai girma na kasuwa. Karanta ainihin sake dubawa na marasa lafiya da ke da nau'in 2 da nau'in ciwon sukari na 2, da kuma abubuwan amfani da yara.

Hakanan koya game da jiyya masu tasiri waɗanda ke sa sukarin jini 3.9-5.5 mmol / L barga 24 a rana, kamar yadda yake a cikin mutane masu lafiya.Tsarin Dr. Bernstein, wanda yake rayuwa tare da ciwon sukari sama da shekaru 70, yana bawa manya da yara masu ciwon sukari damar kare kansu daga rikice rikice.

Dogon insulin levemir: cikakken labarin

An ba da kulawa ta musamman don sarrafa ciwon sukari. Levemir shine magani na zabi ga mata masu juna biyu wadanda ke da yawan jini. Binciken bincike mai zurfi ya tabbatar da amincinsa da tasiri ga mata masu juna biyu, da kuma ga yara daga shekaru 2.

Ka tuna fa cewa insulin insulin ya ragu sosai kamar sabo. Ba za a iya tantance ingancin miyagun ƙwayoyi ta bayyanarsa ba. Sabili da haka, bai cancanci siyan Levemir na hannu ba, ta hanyar sanarwa. Sayi shi a cikin manyan shagunan sanannun ma'aikata waɗanda ma'aikatansu sun san ka'idodin adana kuma basu da saurin cika su.

Umarnin don amfani

Aikin magungunaKamar sauran nau'ikan insulin, Levemir yana saukar da sukari jini, yana haifar da hanta da ƙwayoyin tsoka don ɗaukar glucose. Wannan kwayar tana kuma karfafa sinadaran gina jiki da kuma canza glucose zuwa mai. An tsara shi don rama ciwon sukari na azumi, amma baya taimaka wajen ƙara yawan sukari bayan cin abinci. Idan ya cancanta, yi amfani da ɗan gajeren zango ko ultrashort ban da insemir detemir na dogon lokaci.
PharmacokineticsKowane allura na miyagun ƙwayoyi yana tsawanta fiye da allurar matsakaiciyar insulin Protafan. Wannan kayan aikin ba shi da babban matakin aiki. Umarni na hukuma ya ce Levemir yana aiki sosai fiye da Lantus, wanda shine babban mai fafatawa. Koyaya, masu samar da insulin na Lantus basu da tabbas da wannan :). A kowane hali, sabuwar ƙwayar Tresiba tana rage sukari a cikin masu ciwon sukari na tsawon lokaci (har zuwa awanni 42) kuma sun fi Levemir da Lantus laushi.
Alamu don amfaniNau'i na 1 da nau'in ciwon sukari na 2, wanda ke buƙatar allurar insulin don samun sakamako mai kyau ga mai narkewar ƙwayar cutar glucose. Ana iya tsara shi ga yara fara daga shekara 2, har ma fiye da haka ga manya da tsofaffi. Karanta labarin "Jiyya don Ciwon Cutar 1 a cikin manya da Yara" ko "Insulin don Ciwon Cutar 2". Levemir shine magani na zabi ga yara masu ciwon sukari waɗanda ke buƙatar ƙananan allurai ƙasa da raka'a 1-2. Domin ana iya narkewa, sabanin insulin Lantus, Tujeo da Tresiba.

Lokacin yin allura na Levemir, kamar kowane nau'in insulin, kuna buƙatar bin abinci.

Type 2 ciwon sukari Type 1 ciwon sukari Abincin tebur No. 9 menu na mako-mako: Samfura

ContraindicationsAllergic halayen insulin detemir ko karin abubuwan taimako a cikin abun da ya allura. Babu bayanai daga binciken asibiti game da wannan magani wanda ya shafi yara masu fama da cutar sukari a ƙarƙashin shekara 2. Koyaya, babu irin wannan bayanan don faɗan nau'ikan insulin. Saboda haka ana amfani da Levemir ba bisa ƙa'ida ba don rama ciwon sukari koda a cikin ƙananan yara. Haka kuma, ana iya dilita.
Umarni na musammanBinciki wani labarin game da yadda cututtukan cututtuka, matsananciyar damuwa da matsananciyar damuwa, da yanayin ke shafan bukatun insulin na masu ciwon sukari. Karanta yadda ake hada ciwon sukari da insulin da giya. Kada ku kasance mai laushi don yin allurar Levemir sau 2 a rana, kada ku iyakance kanku da allura guda ɗaya kowace rana. Wannan insulin za a iya narkar dashi idan ya cancanta, sabanin shirye-shiryen Lantus, Tujeo da Tresiba.

Nuna sukari ko zaɓi jinsi don shawarwari

SashiYi nazarin labarin, "Lissafin Long insulin allurai don allurar cikin dare da safe." Zabi mafi kyau duka kashi, kazalika da jadawalin allura daban-daban, bisa ga sakamakon lura da sukari na jini na kwanaki da yawa. Karka yi amfani da daidaitaccen shawarwarin don farawa da 10 IEarfafawa ko 0.1-0.2 PIECES / kg. Ga masu fama da cutar siga da ke bin karafan carb, wannan ya yi yawa sosai. Kuma har ma fiye da haka ga yara. Karanta kayan shima “Gudanar da insulin: a ina kuma yadda ake tsini”.
Side effectsSakamakon sakamako mai haɗari shine ƙananan sukari na jini (hypoglycemia).Fahimci menene alamun wannan rikitarwa, yadda za a taimaka wa mara haƙuri. A wuraren injections na iya zama ja da ciwan ciki. Severearin ƙarin halayen rashin lafiyan halayen ne da wuya. Idan shawarar ta keta shawarar, sauran wuraren allura na iya bunkasa lipohypertrophy.

Yawancin masu ciwon sukari waɗanda ke bi da insulin sun gaza yiwuwa su guji yawan zubar jini. A zahiri, wannan ba haka bane. Kuna iya kiyaye sukari daidai har ma da mummunan cutar kansa. Kuma har ma fiye da haka, tare da gwada da laushi kamar nau'in ciwon sukari 2. Babu buƙatar ƙara girman matakin glucose na jini don insure kanka game da haɗarin hypoglycemia. Kalli bidiyon da Dr. Bernstein ya tattauna game da wannan batun.

Yin hulɗa tare da wasu magungunaMagungunan da za su iya inganta tasirin insulin sun haɗa da allunan rage sukari, da inhibitors na ACE, rashin biyayya, fibrates, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates da sulfonamides. Suna iya raunana tasirin injections: danazol, diazoxide, diuretics, glucagon, isoniazid, estrogens, gestagens, phenothiazine derivatives, somatotropin, epinephrine (adrenaline), salbutamol, terbutaline da cututtukan thyroid, abubuwan hana kariya, olanzapine, Yi magana da likitanka game da duk magungunan da ka sha!
Yawan damuwaIdan kashi da aka gudanar ya yi yawa ga mai haƙuri, zazzabin cizon sauro na iya faruwa, tare da ƙwaƙwalwar ƙwaƙwalwa da ƙwaƙwalwa. Sakamakonsa ba zai iya juyawa ga kwakwalwa ba, har ma da mutuwa. Ba su da daɗi, sai dai a batun yawan zubar da ruwa. Don Levemir da sauran nau'ikan insulin na dogon lokaci, hadarin yana da ƙarancin yawa, amma ba sifili ba. Karanta nan yadda za a samar da kulawa ta gaggawa ga mara lafiya.
Fom ɗin sakiLevemir yana kama da tsabtataccen bayani mara launi. Ana sayar da shi cikin katako 3 ml. Wadannan katakanan za'a iya sawa cikin FlexPen kayan maye wanda za'a iya amfani dashi tare da sashi na 1 na sashi. Magunguna ba tare da alkalami na syringe ba ana kiran shi Penfill.
Sharuɗɗan da yanayin ajiyaKamar sauran nau'ikan insulin, magani Levemir yana da rauni sosai, yana iya saurin lalacewa. Don gujewa wannan, yi nazarin dokokin ajiya kuma a bi su a hankali. Rayyan katifar bayan budewa shine makonni 6. Magungunan, wanda har yanzu ba a fara amfani dashi ba, za'a iya ajiye shi a cikin firiji don shekaru 2.5. Kar a daskare! Ayi nesa da isar yara.
Abun cikiAbunda yake aiki shine insulin. Wadanda suka kware - glycerol, phenol, metacresol, zinc acetate, sodium hydrogen phosphate dihydrate, sodium chloride, hydrochloric acid ko sodium hydroxide, ruwa don yin allura.

Duba ƙasa don ƙarin bayani.

Shin, ana iya samarda insulin a ciki? Dogo ne ko gajeru?

Levemir insulin aiki ne mai dadewa. Kowane kashi ana sarrafa lowers sukari na jini a cikin awanni 18 zuwa 24. Koyaya, masu ciwon sukari da ke bin tsarin karas-carb na buƙatar ƙarancin allurai, sau 2-8 ƙasa da na misali.

Lokacin amfani da irin waɗannan sigogin, sakamakon maganin yana ƙare da sauri, a cikin awanni 10-16. Ba kamar matsakaiciyar insulin na Protafan ba, Levemir bashi da ƙudurin magana da aka ambata.

Kula da sabon magani na Tresib, wanda ya fi tsayi, har zuwa awanni 42, kuma mafi inganci.

Levemir ba gajeran insulin bane. Bai dace da yanayi inda ake buƙatar saukar da sukari da sauri ba. Hakanan, bai kamata a sanya shi abinci kafin abinci don rage abincin da mai ciwon sukari yake shirin ci ba. Don waɗannan dalilai, ana amfani da shirye-shiryen gajere ko ultrashort. Karanta labarin “Nau'in Insulin da Tasirinsu” daki-daki daki daki.

Kalli bidiyon Dr. Bernstein. Gano dalilin da ya sa Levemir ya fi Lantus kyau. Fahimci sau nawa a rana kuna buƙatar farashin shi kuma a wani lokaci. Bincika cewa kuna adana insulin kuli-kuli don kada ya lalace.

Yadda za a zabi kashi?

Yawan Levemir da sauran nau'ikan insulin dole ne a zabi su daban-daban.Ga masu ciwon sukari na manya, akwai ingantacciyar shawarar da za a fara da 10 KUDI ko 0.1-0.2 LATSA / kg.

Koyaya, ga marasa lafiya da ke bin abincin karam, wannan kashi zai yi yawa. Lura da sukarin jininka tsawon kwanaki. Zaɓi mafi kyau sashi na insulin ta amfani da bayanan da aka karɓa.

Karanta karin bayani a cikin labarin "Lissafin allurai na dogon insulin don allurar cikin dare da safe."

Nawa ne amfanin wannan maganin don shigar da shi cikin yaro mai shekaru 3?

Ya dogara da irin nau'in abincin da yaro mai ciwon sukari yake bi. Idan an canza shi zuwa abincin abinci mai ƙanƙantarwar abinci, to, allurai kaɗan, kamar dai homeopathic, za'a buƙaci hakan.

Wataƙila, kuna buƙatar shiga Levemir da safe da maraice a allurai waɗanda basu wuce 1 raka'a ba. Kuna iya farawa da raka'a 0.25. Don yin daidai da irin waɗannan allurai kaɗan, yana da mahimmanci don tsarmar maganin masana'antar don yin allura.

Karanta ƙarin game da shi anan.

A lokacin sanyi, guban abinci da sauran cututtukan cututtuka, ya kamata a kara yawan insulin kimanin sau 1.5. Lura cewa shirye-shiryen Lantus, Tujeo da Tresiba ba za a iya gurbata su ba.

Saboda haka, ga ƙananan yara na nau'ikan insulin, kawai Levemir da Protafan suna saura. Yi nazarin labarin "Ciwon sukari a cikin Yara."

Koyi yadda za ku fadada lokacin tafiyar ku kuma ku tabbatar da kyakkyawan ikon sarrafa glucose na yau da kullun.

Ilimin insulin: yadda ake zaba kwayoyi Long insulin don injections da daddare da safe Kuyi lissafin kashi na insulin azumi kafin abinci Insulin na insulin: inda kuma yadda ake yin allura

Ta yaya za a tsayar da Levemir? Sau nawa a rana?

Levemir bai isa ya saka farashi sau ɗaya a rana ba. Dole ne a gudanar dashi sau biyu a rana - safe da dare. Haka kuma, aikin kashi na maraice yawanci bai isa ba duk daren. Saboda wannan, masu ciwon sukari na iya samun matsaloli tare da glucose da safe a kan komai a ciki. Karanta labarin "Sugar a kan komai a ciki da safe: yadda za a dawo da shi al'ada". Hakanan bincika kayan "Inulin insulin: ina kuma yadda ake yin allura".

Shin za a iya kwatanta wannan magani da Protafan?

Levemir ya fi Protafan kyau. Abubuwan insulin na protafan ba su tsawan tsayi, musamman idan allurai basu da yawa. Wannan magani ya ƙunshi furotin furotin na dabba, wanda yawanci yakan haifar da rashin lafiyan halayen.

Zai fi kyau ki ƙi amfani da insulin protafan. Ko da an ba da wannan magani kyauta, kuma sauran nau'ikan insulin masu aiki da tsayi za a sayo su da kuɗi. Je zuwa Levemir, Lantus ko Tresiba.

Karanta karin bayani a labarin “iri irin insulin da Tasirinsu”.

Wanne ya fi kyau: Levemir ko Humulin NPH?

Humulin NPH wani insulin ne mai matsakaici, kamar Protafan. NPH shine protamine na tsaka tsaki na Hagedorn, furotin guda wanda yakan haifar da rashin lafiyan yanayi. halayen. Bai kamata a yi amfani da Humulin NPH don dalilai iri ɗaya ba kamar Protafan.

Levemir Penfill da Flekspen: Menene Banbancin?

Flekspen sune allon alkalami wanda aka sa kwalliya a jikin katako wanda aka kera Levemir.

Penfill magani ne na Levemir wanda ake siyarwa ba tare da ƙyamar sirinji don haka zaka iya amfani da sirinjin insulin na yau da kullun. Fensspen alkalami yana da sashi na 1 na sashi.

Wannan na iya zama da wahala cikin lura da ciwon sukari a cikin yaran da ke buƙatar karancin allurai. A irin waɗannan halayen, yana da kyau a samo kuma amfani da Penfill.

Levemir bashi da alamun analogues mai arha. Saboda tsari yana kiyaye shi ta wani lamuni wanda ingancinsa bai ƙare ba. Akwai nau'ikan nau'ikan insulin na dogon lokaci daga wasu masana'antun. Waɗannan magungunan Lantus, Tujeo da Tresiba ne.

Kuna iya nazarin cikakkun labarai game da kowannensu. Koyaya, duk waɗannan magungunan ba su da arha. Matsakaici na tsawon lokaci, irin su Protafan, sun fi araha. Koyaya, yana da mahimmancin halayen saboda wanda Dr. Bernstein da kuma shafin yanar gizon haƙuri na endocrin.

com baya bada shawarar amfani da shi.

Levemir ko Lantus: wane insulin ne ya fi kyau?

An ba da cikakken amsar wannan tambaya a cikin labarin akan insulin Lantus.Idan Levemir ko Lantus sun dace da ku, to ku ci gaba da amfani da shi. Kada ku canza magani ɗaya zuwa wani sai dai idan takan zama dole.

Idan kuna shirin fara allurar dogon insulin ne, to sai a fara Levemir da farko. Sabuwar insulin ta Treshiba ta fi Levemir da Lantus kyau, saboda yana dadewa kuma ya yi laushi sosai.

Koyaya, yana da kusan kusan sau 3 mafi tsada.

Levemir yayin daukar ciki

An gudanar da babban binciken asibiti wanda ya tabbatar da aminci da tasiri na gudanarwar Levemir yayin daukar ciki.

Tsarin insulin nau'ikan Lantus, Tujeo da Tresiba ba zasu iya yin alfahari da wannan tabbataccen shaidar amincin su ba.

A ba da shawarar mace mai juna biyu da ke da yawan sukari mai jini sosai ta fahimci yadda ake lissafin allurai da suka dace.

Insulin bashi da hadari ko dai ga mahaifiyar ko kuma tayi, idan har aka zaɓi sashi. Cutar sankarar mahaifa, idan ba a kula da ita ba, na iya haifar da manyan matsaloli. Sabili da haka, yi ƙarfin zuciya da allurar Levemir idan likita ya umurce ku da yin hakan. Yi ƙoƙarin yin ba tare da maganin insulin ba, bin ingantaccen tsarin abinci. Karanta labaran "Cutar Cutar Ciki" da "Ciwon Cutar na ciki" don ƙarin bayani.

An yi amfani da Levemir don sarrafa nau'in 2 da nau'in 1 na ciwon sukari tun daga tsakiyar 2000s. Kodayake wannan maganin yana da ƙarancin magoya baya fiye da Lantus, isassun sake dubawa sun tara tsawon shekaru. Mafi yawansu suna da inganci. Marasa lafiya lura cewa insulin detemir da kyau lowers jini sukari. A lokaci guda, haɗarin ciwo mai ƙarfi yana ragu sosai.

Matan da suka yi amfani da Levemir a lokacin da suke cikin ciki sun rubuto yawancin abubuwan da aka sake duba su ne don magance ciwon sikari. Ainihin, waɗannan marasa lafiya sun gamsu da maganin. Ba jaraba bane, bayan an haihuwar allura na haihuwa ba tare da matsaloli ba. Ana buƙatar daidaituwa don kada kuyi kuskure tare da sashi, amma tare da sauran shirye-shiryen insulin daidai yake.

A cewar marasa lafiya, babban koma-bayan shi ne cewa dole ne a yi amfani da katun a cikin kwanaki 30. Wannan ya yi guntu da wani lokaci. Yawancin lokaci dole ne ku zubar da manyan ma'aunan da ba a amfani da su ba, kuma bayan duk abin, an biya musu kuɗi. Amma duk magunguna masu gasa suna da matsala iri ɗaya. Nazarin masu ciwon sukari sun tabbatar da cewa Levemir ya fi matsakaicin matsakaiciyar insulin Protafan ta kowane fannoni muhimmanci.

Insulin LEVEMIR: sake dubawa, umarni, farashi

Levemir Flexpen kwatanci ne na insulin ɗan adam kuma yana da tasirin hypoglycemic. Levemir an samar dashi ne ta hanyar karin kwayar halitta ta sake amfani da DNA ta amfani da cerechaiae Saccharomyces.

Yana da kwaskwarimar ma'anar insulin na ɗan adam tare da tasiri na tsawan lokaci da yanayin ɗakin kwana wanda yake da ƙima, idan aka kwatanta shi da insulin glargine da isofan-insulin.

Tsawancin wannan maganin yana faruwa ne sakamakon cewa kwayoyin detemir insulin suna da ikon yin tarayya da su a wurin allurar, sannan kuma sun daure wa albumin ta hanyar hada su da sashin kiba mai kiba.

Insulin na Detemir ya kai gaɓoɓin ƙwaƙwalwar mahaifa a hankali fiye da isofan-insulin. Wannan haɗin na jinkirin kayan aikin jinkiri yana ba da damar furofayil ɗin ɗaukar hoto da aikin Levemir Penfill fiye da isofan-insulin.

Lokacin da aka ɗaura takamaiman masu karɓa a kan membrane na cytoplasmic na insulin, insulin ya samar da hadaddun ƙira na musamman wanda ke ƙarfafa haɗarin enzymes masu mahimmanci a cikin sel, irin su hexokinase, glycogen synthetase, pyruvate kinase da sauransu.

Babban nuni ga amfanin Levemir Flexpen shine ciwon sukari.

Contraindications

Bai kamata a rubuta insulin tare da ƙara yawan hankalin mutum don cire detulin ko wani abin da ke cikin abubuwan da ke ciki.

Ba a yi amfani da Levemir Flexpen a cikin yara 'yan ƙasa da shekaru shida ba, tunda ba a yi nazarin asibiti a kan ƙananan yara ba.

Sashi da gudanarwa

Don Levemir Flexpen, ana amfani da hanyar subcutaneous na gudanarwa. Ana yin amfani da adadin da adadin inje in akayi daban-daban ga kowane mutum.

Idan ana maganar magunguna tare da wakilai masu rage sukari don sarrafa bakin, ana yaba yin amfani da shi sau ɗaya a rana akan maganin 0.1-0.2 U / kg ko 10 U.

Idan ana amfani da wannan magani azaman tsarin tushen-bolus, to an tsara shi gwargwadon bukatun mai haƙuri 1 ko sau 2 a rana. Idan mutum yana buƙatar yin amfani da insulin sau biyu don kula da ingantaccen glucose, to, ana iya gudanar da maganin maraice a lokacin abincin dare ko a lokacin barci ko bayan sa'o'i 12 bayan safiya.

Inje na Levemir Penfill an allurar dashi a cikin kafaɗa, bangon ciki na ciki ko yankin cinya, ana iya samun cikakkun bayanai kan yadda ake allurar insulin a cikin cutar sikari. Ko da an yi allura a ɗayan sashin jiki, an buƙaci canza wurin allurar.

Gyara daidaitawa

A cikin marasa lafiya a cikin tsufa ko a gaban renal ko hepatic kasawa, gyara kashi na wannan magani ya kamata a za'ayi, kamar yadda sauran insulin. Farashi bai canza daga wannan ba.

Ya kamata a zaba yawan insulin din insemir daban-daban tare da lura da lura da glucose a cikin jini.

Hakanan, sake dubawa ya zama dole tare da kara yawan motsa jiki na mai haƙuri, kasancewar cututtukan haɗuwa ko canji a cikin abincinsa na yau da kullun.

Juyawa daga wasu shirye-shiryen insulin

Idan akwai buƙatar canja wurin mai haƙuri daga insulin tsawanta ko magunguna na matsakaiciyar lokacin aiki akan Levemir Flexpen, to ana iya buƙatar canji a cikin tsarin kulawar na wucin gadi, kazalika da daidaita sashi.

Kamar yadda ake amfani da wasu kwayoyi masu kama da juna, ya zama dole a sa ido sosai a kan abubuwan da ke cikin glucose na jini yayin sauyin kanta da kuma lokacin fewan makonni na farko na amfani da sabon magani.

A wasu halaye, dole ne a sake nazarin hanyoyin magance matsalar rashin daidaituwa, alal misali, kashi na miyagun ƙwayoyi don maganin baka ko kuma sashi da lokacin gudanar da shirye-shiryen insulin na gajeran lokaci.

Yi amfani da lokacin daukar ciki da lactation

Babu ƙwarewar asibiti da yawa tare da amfani da Levemir Flexpen a lokacin haihuwar yaro da shayarwa. A cikin nazarin aikin haihuwa a cikin dabbobi, babu bambance-bambance a cikin tayi da teratogenicity tsakanin insulin mutum da insulin detemir.

Idan mace ta kamu da cutar sankarar mahaifa, lura sosai wajibi ne duka a matakan tsarawa da kuma tsawon lokacin haila.

A cikin farkon farkon, yawanci bukatar insulin ya ragu, kuma a cikin lokuta masu zuwa na ƙaruwa. Bayan haihuwa, yawanci wannan buƙatun wannan hanzari ya fara zuwa matakin farko wanda yake kafin lokacin daukar ciki.

Yayin shayarwa, mace na iya buƙatar daidaita abincin ta da kuma yawan insulin.

Side sakamako

A matsayinka na doka, sakamako masu illa a cikin mutane da ke amfani da miyagun ƙwayoyi Levemir Flexpen suna dogara ne kai tsaye akan kashi kuma sune sakamakon aikin magunguna na insulin.

Sakamakon mafi munin illa shine cututtukan jini. Yana faruwa lokacin da aka gudanar da magunguna masu yawa da suka wuce buƙatun jiki na insulin.

Nazarin asibiti ya nuna cewa kusan 6% na marasa lafiya da ke shan magani na Levemir Flexpen suna haɓaka ƙarancin cututtukan cututtukan jini waɗanda ke buƙatar taimakon wasu mutane.

Amsawa ga gudanar da miyagun ƙwayoyi a wurin allura lokacin amfani da Levemir Flexpen sun fi yawa fiye da lokacin da aka bi da su tare da insulin mutum. An bayyana wannan ta hanyar redness, kumburi, kumburi da itching, kurma a wurin allurar.

Yawanci, irin waɗannan halayen ba a furta kuma suna kasancewa na ɗan lokaci (ɓace tare da ci gaba da jiyya na kwanaki ko makonni).

Haɓaka sakamako masu illa a cikin marasa lafiya da ke gudana tare da wannan magani yana faruwa a cikin kusan kashi 12% na lokuta. Duk mummunan halayen da miyagun ƙwayoyi suka haifar Levemir Flexpen sun kasu kashi biyu:

  1. Tsarin abinci na rayuwa da rashin abinci mai gina jiki.

Mafi yawan lokuta, cututtukan jini suna faruwa, suna da alamomin masu zuwa:

  • gumi mai sanyi
  • gajiya, gajiya, rauni,
  • pallor na fata
  • jin damuwa
  • tashin hankali ko rawar jiki,
  • rage hankali span da disorientation,
  • jin karfi na yunwar
  • ciwon kai
  • karancin gani
  • karuwar zuciya.

A cikin matsanancin rashin ƙarfi, mai haƙuri na iya rasa hankali, zai iya fuskantar cramps, rikicewar wucin gadi ko ba a iya warwarewa a cikin kwakwalwa na iya faruwa, kuma sakamako mai kisa na iya faruwa.

  1. Amsawa a wurin allurar:
  • redness, itching da kumburi sau da yawa ana faruwa a wurin allurar. Yawancin lokaci suna ɗan lokaci kuma suna wucewa tare da ci gaba da jiyya.
  • lipodystrophy - da wuya ya faru, yana iya farawa saboda gaskiyar cewa dokar canza wurin allura a cikin yanki ɗaya ba a mutunta shi
  • edema na iya faruwa a farkon matakan insulin.

Duk waɗannan halayen ba yawanci ba ne.

  1. Canje-canje a cikin tsarin rigakafi - fatar fata, amya, da sauran halayen rashin lafiyan jiki na iya faruwa a wasu lokuta.

Wannan shi ne sakamakon jigilar cutarwar jiki. Sauran alamun na iya haɗawa da ɗumi, amai, amai, raunin jijiyoyi, wahalar numfashi, saukar da saukar karfin jini, da bugun zuciya.

Bayyanar bayyanar cututtukan da ke haifar da rashin daidaituwa (maganganun anaphylactic) na iya zama haɗari ga rayuwar mai haƙuri.

  1. Rashin gani da gani - a lokuta da ƙarancin yanayi, cututtukan fuka-fukan ciwon sikila ko kuma raunin nakuda na iya faruwa.

Haihuwa da lactation

Lokacin amfani da Levemir ® FlexPen ® yayin daukar ciki, ya zama dole a yi la’akari da girman amfanin amfanin sa fiye da yuwuwar haɗari.

Ofaya daga cikin gwaje-gwaje na asibiti da aka sarrafa ba tare da mata masu juna biyu da nau'in ciwon sukari na 1 na ciki ba, wanda inganci da amincin haɗaka tare da Levemir ® FlexPen ® tare da insulin aspart (152 mata masu juna biyu) idan aka kwatanta da insulin-isofan hade da insulin aspart ( 158 mata masu juna biyu), basu bayyana bambance-bambance a bayanin martaba na gaba daya ba a lokacin daukar ciki, a sakamakon ciki ko a tasirin lafiyar tayin da jarirai (duba "Pharmacodynamics", "Pharmacokinetics" )

Dataarin bayanai kan inganci da amincin magani tare da Levemir ® FlexPen ® waɗanda aka samu a kusan mata masu ciki 300 yayin amfani da bayan-cinikin yana nuna rashin sakamako masu illa na insulin gurɓataccen insulin, wanda ke haifar da lalata da lalata cuta ko cutar feto / neonatal mai guba.

Nazarin aikin haifuwa a cikin dabbobi bai bayyana sakamakon mai guba da miyagun ƙwayoyi kan tsarin haihuwa ba (duba "Pharmacodynamics", "Pharmacokinetics").

Gabaɗaya, kulawa da hankali ga mata masu juna biyu da masu ciwon sukari a duk tsawon lokacin da suke ciki, da kuma lokacin da ake shirin ɗaukar ciki, ya zama dole. Bukatar insulin a cikin farkon farkon haihuwa yawanci yana raguwa, to a cikin na biyu da na uku yana ƙaruwa. Jim kaɗan bayan haihuwa, buƙatar insulin da sauri ya koma matakin da ya kasance kafin yin juna biyu.

Ba'a sani ba ko insulin ya shiga cikin Detemir a cikin madarar nono na mutum.Ana zaton insulin din insemir baya tasiri kan abinda ya shafi jijiyoyi a jikin jarirai / jarirai yayin shayarwa, tunda ya kasance cikin rukunin peptides ne wanda aka rushe cikin hanzarin narkewa cikin amino acid da jiki ya karba.

A cikin mata yayin shayarwa, ana buƙatar daidaita sashin insulin.

Haɗa kai

Akwai kwayoyi da yawa waɗanda ke shafar metabolism metabolism.

Bukatar insulin na iya raguwa magunguna na hypoglycemic na baka, glucagon-like peptide-1 agonists receptor (GLP-1), MAO inhibitors, masu hana beta-blockers, ACE inhibitors, salicylates, steroids anabolic da sulfonamides.

Abubuwan insulin na iya ƙaruwa hana maganin hana haihuwa, maganin thiazide diuretics, corticosteroids, hormones thyroid, mai juyayi, somatropin da danazole.

Masu tallata Beta na iya rufe alamun bayyanar cututtukan jini.

Octreotide / Lanreotide dukansu suna iya haɓaka da rage buƙatar jiki ga insulin.

Ethanol (barasa) duka zasu iya haɓaka da rage tasirin insulin.

Rashin daidaituwa. Wasu kwayoyi, alal misali dauke da thiol ko gungun sulfite, lokacin da aka haɗa su da miyagun ƙwayoyi Levemir ® FlexPen ® na iya haifar da rushewar insulin. Levemir ® FlexPen ® bai kamata a kara shi zuwa hanyoyin magance jiko ba. Kada a hada wannan magani da wasu kwayoyi.

Sashi da gudanarwa

Ana iya amfani da miyagun ƙwayoyi Levemir ® FlexPen ® duka a matsayin monotherapy kamar insulin basal, kuma a hade tare da insalin '' bolus insulin '. Hakanan za'a iya amfani dashi a hade tare da magungunan maganin hypoglycemic na baki da / ko kuma agonists na karɓar GLP-1.

A hade tare da magungunan maganin hypoglycemic na baki ko ƙari ga agonists na masu karɓa na GLP-1 a cikin marasa lafiyar manya, ana ba da shawarar yin amfani da Levemir ® FlexPen ® sau ɗaya a rana, farawa da 0.1-0.2 U / kg ko 10 UNITS.

Levemir ® FlexPen ® ana iya gudanar dashi a kowane lokaci cikin rana, amma kullun a lokaci guda. Za'a zaɓi zaɓin Levemir ® FlexPen individ daban-daban a kowane yanayi, gwargwadon bukatun mai haƙuri.

A yayin da ka hada da maganin kara karfin jini na GLP-1 zuwa Levemir ®, ana bada shawarar rage kashi na Levemir ® da kashi 20% don rage hadarin dake tattare da cutar hawan jini. Bayan haka, ya kamata a zaɓi kashi ɗin daban daban.

Don daidaita daidaituwa na mutum a cikin marasa lafiyar manya tare da nau'in ciwon sukari na 2 na sukari, ana ba da shawarar tititi mai zuwa (duba Table 1).

Matsayin glucose na plasma ana auna kansa daban kafin karin kumalloGyaran gyaran magunguna Levemir ® FlexPen ®, ED
> 10 mmol / L (180 mg / dL)+8
9.1-10 mmol / L (163-180 mg / dl)+6
8.1-9 mmol / L (145-162 mg / dl)+4
7.1-8 mmol / L (127- 144 mg / dl)+2
6.1-7 mmol / L (109-126 mg / dl)+2
4.1-6 mmol / L (73-108 mg / dl)Babu canji (darajar manufa)
3.1-4 mmol / L (56-72 mg / dl)-2
Ana amfani da FlexPen ® a matsayin wani ɓangaren tsarin kulawa na ƙoshin lafiya na bolus, ya kamata a tsara shi sau 1 ko 2 a rana gwargwadon bukatun mai haƙuri. Ya kamata a zaɓi kashi na Levemir ® FlexPen ® daban daban.

Marasa lafiya waɗanda ke buƙatar yin amfani da miyagun ƙwayoyi sau biyu a rana don ingantaccen iko na glycemic, suna iya shigar da kashi na yamma ko dai lokacin abincin dare ko kafin lokacin kwanciya. Gyaran matsakaita na iya zama dole yayin da ake inganta ayyukan jikin mai haƙuri, canza tsarin abincinsa na yau da kullun ko rashin lafiyar da ke tattare da shi.

Canja wuri daga sauran shirye-shiryen insulin. Canja wuri daga tsaka-tsakin matsakaici ko shirye-shiryen insulin na dogon lokaci zuwa Levemir ® FlexPen ® na iya buƙatar sakin abu da daidaita lokaci (duba "Umarnin na Musamman").

Kamar yadda yake tare da sauran shirye-shiryen insulin, yin saurin kulawa da maida hankali kan ƙwayar glucose jini yayin canja wuri kuma a farkon makonni na rubuta sabon magani ana bada shawara.

Ana iya buƙatar gyaran concomitant na maganin rashin daidaituwa (kashi da lokacin gudanar da shirye-shiryen insulin gajere ko kuma magunguna na magana da baki).

Hanyar aikace-aikace. Levemir ® FlexPen ® an yi shi ne don sc አስተዳደር kawai. Levemir ® FlexPen ® ba za a iya sarrafa shi iv ba. wannan na iya haifar da matsanancin rashin ƙarfi a jiki. Hakanan wajibi ne don kauce wa allurar IM ta miyagun ƙwayoyi. Ba za a iya amfani da Levemir ® FlexPen in a cikin famfon na insulin ba.

Levemir ® FlexPen ® allurar allura ce zuwa cikin yankin bangon baya na ciki, a cinya, gindi, kafada, yanki ko gluteal. Ya kamata a canza wuraren allurar koyaushe a cikin wannan yanki na jiki don rage haɗarin lipodystrophy. Kamar yadda yake tare da sauran shirye-shiryen insulin, tsawon lokacin aiki ya dogara da kashi, wurin gudanarwa, yawan zubar jini, yawan zafin jiki da kuma matakin motsa jiki.

Groupsungiyoyin haƙuri na musamman

Kamar sauran shirye-shiryen insulin, a cikin tsofaffi marasa lafiya da marasa lafiya da keɓaɓɓen renal ko hepatic insufficiency, ya kamata a kula da tattarawar glucose na jini da kulawa da daidaituwa na ƙayyadaddun abubuwa daban-daban.

Yara da matasa. Ana iya amfani da miyagun ƙwayoyi Levemir ® don kula da matasa da yara da suka girmi shekara 1 (duba "Pharmacodynamics", "Pharmacokinetics"). Lokacin canzawa daga insulin basal zuwa Levemir ®, ya zama dole a kowane yanayi don la'akari da buƙatar rage yawan ƙwayar basal da bolus don rage haɗarin hypoglycemia (duba. "Umarni na musamman").

Ba a bincika aminci da tasiri na Levemir children a cikin yara 'yan ƙasa da shekara 1 ba. Babu bayanai.

Umarnin don haƙuri

Kada kayi amfani da Levemir ® FlexPen ®

- dangane da rashin lafiyan (rashin hankalin) to insulin, detemir ko duk wani abin da ya hada da maganin,

- idan mai haƙuri ya fara zubar da jini (ƙananan ƙwayar jini),

- a cikin famfo na insulin,

- Idan an jefa alƙalin 'FringPen ® syringe pen, ya lalace ko ya kakkarye,

- idan an keta yanayin ajiya na miyagun ƙwayoyi ko ya daskare,

- Idan insulin ya daina nuna gaskiya da launi.

Kafin amfani da Levemir ® FlexPen ®, ya wajaba

- bincika alamar don tabbatar cewa mara lafiyar yana amfani da nau'in insulin da ya dace,

- koyaushe yi amfani da sabon allura don kowane allura don hana kamuwa da cuta,

- lura cewa Levemir ® FlexPen ® da allura an yi niyya ne don amfanin mutum kawai.

Levemir ® FlexPen ® an yi shi ne don sc አስተዳደር kawai. Kada a taɓa shigar da shi cikin / a ciki ko cikin / m. Kowane lokaci, canza wurin allura a cikin yankin ilimin halittu. Wannan yana rage haɗarin seals da ulcerations a wurin allurar. Zai fi kyau a saka allurar a gaban cinya, a kwancen kafa, bangon ciki da kafada. A kai a kai ka auna guluk din jininka.

Dole ne a hankali karanta waɗannan umarnin kafin amfani da Levemir ® FlexPen ®. Idan mara lafiya bai bi umarnin ba, yana iya yin isasshen insulin na insulin wanda ba shi da yawa ko kuma mai yawa, wanda na iya haifar da yawan zubar da jini mai yawa sosai ko mara yawa.

Flexpen® shine alkalami mai sikirin insulin wanda aka cika shi da mai jigilar mai. Matsakaicin insulin, a cikin kewayon daga raka'a 1 zuwa 60, na iya bambanta a cikin adadin 1 raka'a. An tsara FlexPen ® don amfani da NovoFine ® da allurai NovoTvist ® har zuwa tsawon mm 8 mm. A matsayin kiyayewa, koyaushe yana da buqatar ɗaukar kayan sawa tare da kai don gudanar da insulin idan ka rasa ko lalata alkairin Levemir ® FlexPen ®.

Adanawa da kulawa

FlexPen ® Syringe Pen na buƙatar kulawa da hankali. Idan akwai lalacewa ko damuwa mai ƙarfi na injin, alkalami na iya lalacewa kuma insulin na iya zubo.Wannan na iya haifar da rashin daidaituwa, wanda na iya haifarda girman kai ko kuma raguwar yawan glucose.

Ana iya tsabtace farfajiyar FlexPen ® sirinji tare da auduga a ciki. Kada a nutsad da alkalami mai ruwa a cikin ruwa, kada ku wanke ko sanya mai, kamar yadda wannan na iya lalata injin. Ana sake faɗar warware matsalar sirinji na FlexPen ®.

Shiri Levemir ® FlexPen ®

Kafin fara aiki, dole ne a bincika lakabin don tabbatar da cewa Levemir ® FlexPen ® ya ƙunshi nau'in insulin da ake buƙata. Wannan yana da mahimmanci musamman idan mai haƙuri yayi amfani da nau'ikan insulins. Idan yayi kuskure ya saka wani nau'in insulin, to yawan jinin glucose na jini zai iya yawaita ko yayi kasa.

A. Cire kwalkwali daga alkairin sirinji.

B. Cire kwali na kariya daga allura wanda za'a iya cirewa. Miƙa allura da ƙarfi a aljihun syringe.

C. Cire babban hula daga allura, amma kada a jefar dashi.

D. Cire ka zubar da kwarin ciki na allura. Don hana allurar bazata, kar a sake sanya murfin ciki da allura.

Bayani mai mahimmanci. Yi amfani da sabon allura don kowane allura. Wannan yana rage haɗarin kamuwa da cuta, kamuwa da cuta, yaduwar insulin, toshewar allura da gabatarwar kashi mara kyau na miyagun ƙwayoyi.

Yi amfani da allura da kulawa don kar a lanƙwasa ko lalata shi kafin amfani.

Duba insulin

Ko da tare da amfani da alkalami yadda ya kamata, karamin adadin iska na iya tarawa a cikin kicin kafin kowane allurar. Don hana shigowar kumfa iska da tabbatar da bayyanar da daidai ƙwayar magani:

E. Buga raka'a 2 na miyagun ƙwayoyi ta hanyar juya zaɓin mai zaɓin.

F. Yayin riƙe alkalami na FlexPen with tare da allura sama, taɓa maɓallin katako a ɗan 'yan yatsun hannunka don yadda kumburin iska ya hau saman katun.

G. Riƙe alkalami na syringe tare da allura sama, danna maɓallin farawa gaba ɗaya. Mai zazzabin kashi zai koma sifili. Wani digo na insulin yakamata ya bayyana a ƙarshen allura. Idan wannan bai faru ba, maye gurbin allura kuma maimaita hanya, amma ba fiye da sau 6.

Idan insulin bai fito daga allura ba, wannan yana nuna cewa alkairin sirar yana da lahani kuma bai kamata a sake amfani da shi ba. Yi amfani da sabon alkalami.

Bayani mai mahimmanci. Kafin kowane allura, tabbatar cewa digo na insulin ya bayyana a ƙarshen allura. Wannan yana tabbatar da isar da insulin. Idan digo na insulin bai bayyana ba, ba za a gudanar da maganin ba, koda kuwa mai zaɓin kashi ya motsa. Wannan na iya nuna cewa allura ta toshe ko ta lalace.

Binciki isar da insulin kafin kowane allura. Idan mara lafiya bai duba iskar insulin ba, to ba zai iya yin isasshen kashi na insulin ba ko kuma kwata-kwata, wanda hakan na iya haifar da yawan hawan jini a cikin jini.

Tabbatar cewa an saita mai zaɓi zuwa “0”.

H. Theara yawan adadin abubuwan da ake buƙata don allurar. Za'a iya yin gyaran ta hanyar juyawa mai zaɓin sashi a kowane bangare har sai an saita madaidaicin kashi a gaban mai nuna sashi. Lokacin juyawa mai zaɓin sashi, dole ne a kula da kada a bazata danna maɓallin farawa don hana fitowar sashin insulin. Ba zai yiwu ba saita adadin da yawansu ya rage adadin adadin sassan da ke cikin kicin

Bayani mai mahimmanci. Kafin yin allura, koyaushe bincika ma'aunin insulin nawa mara haƙuri ya ci ta hanyar mai zaɓin kashi da alamomin kashi.

Kada a ƙidaya danna maɓallin harafin sirinji. Idan mai haƙuri ya kafa da kuma gudanar da aikin da ba daidai ba, ƙwayar glucose na jini na iya zama ya yi ƙasa sosai ko ƙasa. Matsakaicin ma'aunin insulin yana nuna kimanin adadin insulin da ya saura a alkairin sirinji, don haka ba za'a iya amfani da shi don auna adadin insulin ba.

Saka allura a ƙarƙashin fata. Yi amfani da dabarar allura ta likitanku ko likitan ku.

Ni. Don yin allura, danna maɓallin farawa gaba ɗaya har sai “0” ta bayyana a gaban mai nuna sashi. Yakamata a yi taka tsantsan, lokacin gudanar da maganin, kawai maballin farawa dole ne a matse.

Bayani mai mahimmanci. Lokacin kunna mai zaɓin kashi, ba za'a gabatar da insulin ba.

J. Lokacin cire allura daga ƙarƙashin fata, riƙe maɓallin farawa da bacin rai sosai.

Bayan allura, bar allura a karkashin fata na akalla awanni 6 - wannan zai tabbatar da gabatarwar cikakken insulin.

Bayani mai mahimmanci. Cire allura daga karkashin fata kuma ka saki maɓallin farawa. Tabbatar cewa mai zaɓin kashi ya sake komawa sifili bayan allurar. Idan mai zaɓin kashi ya tsaya kafin a nuna "0", ba a gudanar da cikakken insulin na insulin ba, wanda zai haifar da taro mai yawa a cikin jini.

K. Jagora allura cikin madogara na allura ba tare da taɓa hula ba. Lokacin da allura ta shiga, saka ƙyalli gaba ɗaya kuma cire allurar.

Jefar da allura, lura da kiyayewar kariya, kuma sanya hula a alƙalin sirinji.

Bayani mai mahimmanci. Cire allurar bayan kowane allura kuma adana Levemir ® FlexPen ® tare da allura mai haɗin. Wannan yana rage haɗarin kamuwa da cuta, kamuwa da cuta, yaduwar insulin, toshewar allura da gabatarwar kashi mara kyau na miyagun ƙwayoyi.

Bayani mai mahimmanci. Masu kula da marassa lafiya yakamata suyi amfani da allura da aka yi amfani dasu tare da matsanancin kulawa don rage hadarin inje in bazata da kamuwa da cuta

Yi watsi da FlexPen ® tare da allura an cire haɗin.

Karka taɓa raba alkairin ka da sauran alluran da shi ga wasu. Wannan na iya haifar da kamuwa da cuta da cutar da lafiya.

Kiyaye alkalami mai sirinji da allura su isa ga dukkan mutane, musamman yara.

Mai masana'anta

Wanda ya mallaki takardar rajista: Novo Nordisk A / S, Novo Alle DK-2880 Baggswerd, Denmark.

Wanda aka kirkira ta: Novo Nordisk LLC 248009, Russia, Yankin Kaluga, Kaluga, 2nd Automotive Ave, 1.

Ya kamata a aika da ikirarin masu amfani da kayayyaki zuwa: Novo Nordisk LLC. 121614, Moscow, st. Krylatskaya, 15, na. 41.

Waya: (495) 956-11-32, fax: (495) 956-50-13.

Levemir ® FlexPen ®, NovoFine ® da NovoTvist ® alamun kasuwanci ne masu rijista ta Novo Nordisk A / C, Denmark.

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