Yadda ake amfani da Metglib?

Dukkanin game da ciwon sukari »Yadda ake amfani da karfi na Metglib?

Garfin Metglib yana nufin jami'in hypoglycemic. Yana haɓaka saurin daidaita matakan glucose na jini. Yana da sakamako mai ɗorewa. Amfani da shi don magance cututtukan type 2.

Saki siffofin da abun da ke ciki

Ana samun maganin a cikin nau'ikan allunan a sikelin na 2.5 mg + 500 MG da 5 MG + 500 MG. Babban abubuwan da aka gyara sune glibenclamide da metformin hydrochloride. Sauran abubuwan da aka gabatar an gabatar dasu: sitaci, alli dihydrate, har da macrogol da povidone, karamin adadin cellulose.

Fim ɗin farin farin da aka rufe allunan 5 MG + 500 MG shine Opadra fari, giprolose, talc, dioxide titanium. Allunan suna da layin rarraba.

Allunan 2.5 MG + MG 500 M, an rufe shi da fim mai kariya tare da launin ruwan kasa.

Aikin magunguna

Amintaccen wakili ne wanda ya samo asali, wanda ya samo asali na 2 na zamanin, wanda akayi niyya don maganin baka. Yana da cututtukan cututtukan cututtukan fata da cututtukan cututtukan fata.

Glibenclamide yana haɓaka ingantaccen insulin ta hanyar rage tsinkaye ta ƙwayoyin beta a cikin ƙwayar cuta. Sakamakon karuwar sawar insulin, yana ɗaure ƙwayoyin ƙwayoyin cuta da sauri. Tsarin lipolysis na adipose nama yana sauka a hankali.

Matsayi mafi girma na plasma an kai shi ne bayan sa'o'i 2 bayan shan kashi. Rabin rayuwar glibenclamide yana tsawon lokaci fiye da metformin (kusan awanni 24).

Alamu don amfani

Alamomi don amfani sune shari'o'in masu zuwa:

• nau'in ciwon sukari na 2 a cikin manya, idan abinci da motsa jiki basa taimaka,
• Rashin ingancin magani tare da abubuwan da ake amfani da su na sulfonylurea da kuma metformin,
• don maye gurbin monotherapy tare da magunguna 2 a cikin mutanen da ke da kyakkyawan iko na glycemic.

Ana amfani da magani don nau'in ciwon sukari na 2 a cikin manya, idan abincin da motsa jiki ba su taimaka ba.

Contraindications

Akwai da yawa contraindications ga yin amfani da wannan magani da aka bayyana a cikin umarnin. Daga cikinsu akwai:

• rashin hankali ga abubuwan da ke cikin miyagun ƙwayoyi,
• nau'in ciwon sukari guda 1
• koda mai aiki,
• mai ciwon sukari ketoacidosis,
• m yanayi tare da nama hypoxia,
• ciki da lactation
• cututtuka
• raunin da ya faru da kuma manyan ayyuka,
• amfani da miconazole,
• barasa maye,
• lactic acidosis,
• bi abinci mai karancin kalori,
• yara ‘yan kasa da shekara 18.

Tare da kulawa sosai, an sanya wannan maganin don mutanen da ke fama da cutar ta febrile, giya, aiki mai rauni, glandon gland da kuma glandon thyroid. Hakanan an tsara shi a hankali ga mutanen da ke da shekaru 45 da haihuwa (saboda yawan haɗarin cututtukan jini da na lactic acidosis).

Yadda ake ɗaukar ƙarfin Metglib?

Allunan don amfani na baka ne kawai. An zabi sashi daban-daban, la'akari da tsananin tsananin bayyanuwar asibiti.

Fara da kwamfutar hannu 1 a kowace rana tare da sigogi na abu mai aiki na 2.5 mg da 500 MG, bi da bi. A hankali ƙara yawan sati kowane mako, amma an ba shi tsananin zafin cutar. Tare da maganin maye gurbin maye gurbin, musamman idan ana aiwatar dashi daban ta metformin da glibenclamide, ana bada shawara a sha Allunan 2 a rana. Matsakaicin izini na yau da kullun kada ya wuce allunan 4 a kowace rana.

Side effects

A lokacin jiyya, haɓaka irin wannan halayen mai yiwuwa ne:

• leuko- dajambara,
• anemia
• anaphylactic shock,
• hawan jini,
• lactic acidosis,
• rage sha na bitamin B12,
• ku ɗanɗani cin zarafi
• rage gani
• tashin zuciya
• amai
• zawo
• rashin ci
• jin wani nauyi a ciki
• aikin hanta mai rauni,
• maganin ciwon kai
• fata halayen
• cututtukan mahaifa
• kurji tare da itching
• erythema
• dermatitis
• karuwa a cikin maida hankali ne urea da creatinine a cikin jini.

Yakamata a sanar da mutane game da hadarin dake tattare da cutar tarin jini da kuma daukar matakai don hana shi kafin samun bayan motan mota ko fara aiki tare da sabbin hanyoyin da ke bukatar kara jawo hankali.

Umarni na musamman

An soke maganin a cikin kulawa da ƙonewa mai yawa, cututtukan da ke kama da cutar, daɗaɗaɗa jiyya kafin manyan aikin tiyata. A irin waɗannan halayen, suna canzawa zuwa daidaitaccen insulin. Hadarin cutar hawan jini yana ƙaruwa tare da nakasa abinci a cikin abinci, tsawan azumi da NSAIDs.

Ba a yarda. Abubuwan da ke aiki suna wucewa ta hanyar kariya daga cikin mahaifa kuma suna iya yin illa ga tsarin kwayoyin halitta.

Ba za ku iya shan kwayoyin lokacin shayarwa ba, saboda Abubuwa masu aiki suna shiga cikin madarar nono. Idan ana bukatar magani, zai fi kyau a bar shayar da jarirai.

Ba'a amfani dashi a ilimin ilimin dabbobi.

Maza da mata sama da 65 suna buƙatar yin hankali, kamar yadda a cikin irin waɗannan mutane, haɗarin haɓakar haɓakar jini yana ƙaruwa sosai.

Yiwuwar amfani da abin ya shafa ta hanyar keɓancewar creatinine. Mafi girma shine, ƙarancin magunguna an wajabta shi. Idan yanayin mai haƙuri ya tsananta, zai fi kyau ka ƙi irin wannan jiyya.

Yarda ba ya karɓa idan aka gano gazawar hanta mai ƙarfi. Wannan yana tattare da aiki mai aiki a cikin hanta kuma yana ba da gudummawa ga lalacewar gwajin aikin hanta.

Yawan damuwa

Tare da yawan abin sama da ya wuce, hypoglycemia na faruwa. Ana iya gyara digiri mai sauƙi ta hanyar amfani da sukari kai tsaye ko abinci mai ɗauke da carbohydrate. Kuna iya buƙatar kashi ko daidaita abinci.

A cikin mawuyacin yanayi, tare da yanayin da bai san komai ba, ana haifar da ciwo mai narkewa ko cutar sankara, maganin glucose ko glucagon intramuscularly. Bayan wannan, yana da kyau a ciyar da mutum abinci mai arziki a cikin carbohydrates mai sauri.

A cikin marasa lafiya tare da raunin hepatic, ƙaddamar da glibenclamide yana ƙaruwa. Ba'a fitar da maganin a cikin dialysis ba, saboda glibenclamide yana ɗaure da kyau ga furotin jini.

Ana amfani da yawan abin sama da ya kamata ne kawai a cikin asibiti, idan ya zo ga acid laisosis. Mafi inganci a wannan yanayin shine maganin hemodialysis.

Yin hulɗa tare da wasu kwayoyi

Yin amfani da miconazole a lokaci guda, fluconazole yana ƙaruwa da yiwuwar rashin lafiyar hypoglycemia. Phenylbutazone yana dakatar da ɗaukar abu mai aiki zuwa tsarin furotin, wanda ke haifar da hauhawar jini da tarawa a cikin jini.

Magunguna tare da abun ciki na iodine da aka yi amfani da su a cikin gwajin X-ray sau da yawa suna rushe aikin koda da tarin metformin. Wannan yana tsokani abin da ya faru na lactic acidosis.

Ethanol yana haifar da halayen disulfiram-kamar. Diuretics rage tasirin tasirin maganin. ACE inhibitors da beta-blockers suna haifar da yanayin hypoglycemic.

Kar a sha kwayoyin hana shan barasa. Wannan yana haifar da matsanancin rashin ƙarfi, yana haifar da wasu sakamako masu illa.

Akwai jerin analogues na wannan magani, kama da shi a cikin abubuwan da ke aiki da sakamako:

• Bagomet Plus,
• Glibenfage
• Glibomet,
• Glucovans,
• Gluconorm,
• Gluconorm Plus,
• Metglib.

Ra'ayoyi game da karfi da karfi na Metglib

Moroz V. A., 38 years, endocrinologist, Arkhangelsk: “Magungunan suna da tasiri. Yanzu na yi kokarin nada shi sau da yawa. Suga tana rike masu ciwon sukari sosai, kusan babu masu illa. ”

Kozerod A.I., mai shekara 50, endocrinologist, Novosibirsk: “Ina son wannan maganin, yana da haƙuri da haƙuri sosai. Na rubuto shi sau da yawa, amma kafin alƙawarin dole ne in nemo waɗancan kantin magunguna ke samuwa. ”

Veronika, yar shekara 32, Moscow: “Mahaifiyata ta dade tana fama da ciwon sukari. Da farko an kula da ita tare da Glybomet. Amma lokacin da ya zama dole a kara kashi, ya zama yayi tsada sosai. An maye gurbin glibomet din ta hanyar Metglib Force, wanda shine mai rahusa. Magungunan yana yin kyakkyawan aiki, har ma da cin zarafin abincin. Ana adana sukari a matakin da hypoglycemia bai dade ba. Abinda kawai ba shi da kyau shine cewa yana da wuya a samu a cikin magunguna. ”

Roman, dan shekara 49, Yaroslavl: “Lokacin da matsayina na sukari ya kai 30 sannan da nike zuwa asibiti ba zato ba tsammani, sai na kamu da ciwon sukari. Sun fara maganin insulin. Daga nan sai na fara mamakin tare da likitan ko zai yiwu a canza daga allura zuwa allunan. Likitan ya ba da shawarar yin amfani da allunan Metglib Force. Na kasance ina amfani da shi tsawon shekaru 2, Na gamsu. Ana kiyaye sukari koyaushe a matakin, babu tsalle-tsalle na dogon lokaci.

Valeria, 'yar shekara 51, Chelyabinsk: “Na sha maganin har kusan shekara guda. Suga na al'ada, babu hauhawar jini, amma na ji ba ni da lafiya, akwai tashin zuciya a koda yaushe. Ya juya cewa ina da matsaloli tare da glandar thyroid. Yanzu mun zaɓi maganin da ya dace. Likita ya bar allunan Metglib Force. Yana da kyau dai dai. ”

Propertiesungiyoyin magunguna na Glibomet

Pharmacodynamics Glibomet shine haɗin glibenclamide da metformin. Haɗin haɗakar abubuwan haɗin guda biyu shine cewa akwai haɓakar ƙwayar insulin wanda ya haifar da glibenclamide, da kuma ƙaruwa sosai a cikin amfani da glucose ta ƙwayar tsoka saboda aikin metformin. Wannan yana haifar da sakamako mai illa, wanda ke ba da izinin rage kashi na kowane ɓangaren ƙwayoyi, don haka rage yawan motsa jiki na β-ƙwayoyin jiki da kuma haɗarin haɓaka ƙarancin aikin su, yana rage haɗarin sakamako masu illa.
Pharmacokinetics Kimanin kashi 84% na glibenclamide yana narkewa a cikin narkewar abinci. Yana cikin metabolized a cikin hanta tare da samuwar metabolites marasa aiki, an cire shi a feces da fitsari. Rabin rayuwar shine awoyi 5. Matsakaicin ɗaukar nauyin sunadaran plasma shine kashi 97%.
Metformin, adsorbed a cikin narkewa, yana cikin hanzari a cikin feces da fitsari, baya daure ga furotin na plasma, kuma baya cikin metabolized a jiki. Rabin rayuwar shine kimanin awa 2.

Yin amfani da miyagun ƙwayoyi Glibomet

Ana amfani da maganin yau da kullun da yawan ƙwayoyi ta likita daban-daban bisa ga yanayin metabolic na haƙuri. Kashi na farko na manya yawanci 2 allunan ne a rana (ɗauki 1 kwamfutar hannu da safe da maraice tare da abinci), kashi na yau da kullun bai wuce allunan 6 ba (2 Allunan sau 3 a rana tare da abinci). Sanya a cikin mafi ƙarancin ƙwaƙƙwaran kashi, samar da isasshen iko na matakin glycemia. Ana iya rage kashi ɗaya na yau da kullun akan lokaci har sai an samar da mafi ƙarancin isa don sarrafa matakan glucose na jini.

Sakamakon sakamako na miyagun ƙwayoyi Glibomet

A cikin halayen da ba a san su ba, yiwuwar haɓakar ƙwayar cuta yana yiwuwa, musamman ma a cikin marassa rauni, tsofaffi, tare da aiki na yau da kullun, tare da cin abinci na yau da kullun ko shan giya, idan akwai hanta mai rauni da / ko aikin koda. Wani lokacin akwai ciwon kai, rikicewar ciki: tashin zuciya, ciwan ciki, gastralgia, amai, gudawa, yana buƙatar katse magani. Wani lokaci, halayen-rashin lafiyar fata suna tasowa, yawanci suna ɗan lokaci kuma suna ɓacewa da kansu tare da ci gaba da magani. Abubuwan da aka bayyana a cikin wallafe-wallafen yiwuwar haɓakar metabolic acidosis a yayin jiyya metformin ba su da wuya. Koyaya, an ba da amintaccen bayyaninsa cewa a cikin marasa lafiya da ke da haɗarin haɗari, irin su renal da m ciwan zuciya, wannan yanayin na iya ɗaukar mataki mai sauri idan ba a tsayar da magani tare da miyagun ƙwayoyi nan da nan kuma ba a dauki matakan likita da suka dace ba. Magungunan haɓaka a cikin matakin lactic acid a cikin ƙwayar jini, karuwa a cikin yawan adadin lactate / pyruvate, raguwa a cikin pH na jini da hyperazotemia sun ba da rahoton (duk lokuta an bayyana su ga marasa lafiya tare da yanayin rashin lahani na ciwon sukari). Haɓaka metabolic acidosis na iya haifar da amfani da giya a lokaci daya a yayin jiyya tare da miyagun ƙwayoyi. Hematopoiesis yana da matukar wuya kuma yawanci ana iya juyawa.

Mu'amala da Magunguna Glibomet

Tasirin hypoglycemic na glibenclamide yana da ƙarfi ta hanyar dicumarol da abubuwan da aka samo ta, MAO inhibitors, magungunan sulfonamide, phenylbutazone da abubuwan da ta samo, chloramphenicol, cyclophosphamide, probenecid, pheniramin, salicylates, miconazole for oral perlera, maganin tafinal, maganin tafinda, maganin tafinda, maganin tafinda, maganin tafinda, maganin tafinda, maganin tafinda, maganin tafintocin, maganin tafintoto, maganin tafintoto, maganin tafintoto, maganin tafintoci, maganin tafintoto, maganin tafintoto, maganin tafintoci, maganin tafintola, maganin jini Sakamakon glibenclamide na iya raunana tare da amfani da kwayar epinephrine, corticosteroids, maganin hana haihuwa, thiazide diuretics da barbiturates. Dole ne a yi taka tsantsan yayin amfani da masu karɓar β-adrenergic tare da masu toshe. Dole ne a ɗauka da hankali cewa biguanides zai iya haɓaka sakamakon maganin anticoagulants.

Yadda ake amfani: sashi da hanya na jiyya

Ana ɗaukar maganin a baka, tare da abinci. An zaɓi tsarinn sashi na Metglib daban-daban, gwargwadon yanayin metabolism.

Yawanci, kashi na farko na Metglib shine kwamfutar hannu 1 (2.5 mg glibenclamide da 500 mg metformin), tare da zaɓin hankali na kashi ɗaya kowane mako 1-2 dangane da glycemic index.

Lokacin maye gurbin maganin haɗuwa da baya tare da metformin da glibenclamide (azaman abubuwan da aka keɓance daban), ana ba allunan 1-2 (2.5 mg glibenclamide da 500 mg metformin), gwargwadon satin da ya gabata na kowane ɓangaren.

Matsakaicin adadin yau da kullun shine Allunan 4 (2.5 ko 5 na glibenclamide da 500 MG na metformin).

Formaddamar da tsari da abun da ke ciki

Akwai shi a cikin nau'ikan allunan biconvex allunan zagaye da farin harsashi. Allunan an tattara su cikin blisters na guda 20. Ana sayar dasu cikin fakiti fakiti na 2, 3 ko 5.

Umarnin don amfani da Glibomet (hanya da sashi)

Likita ya saita tsarin lokacin magani da tsawon lokacin aikinsa daban-daban, ya danganta da matakin sukari na mai jini da kuma irin yanayin aikin shi na carbohydrate.

Maganin farko ya kamata ya zama allunan 1-3 a kowace rana, biye da wani zaɓi na hankali akan mafi ingancin sashi.

Takeauki sau biyu a rana yayin karin kumallo da abincin dare. Aikin yau da kullun bisa ga umarnin kada ya wuce allunan 6.

Hulɗa da ƙwayoyi

• Sakamakon hypoglycemic na miyagun ƙwayoyi na iya ƙara ɗan lokaci yayin ɗaukar shi tare da dicumarol da abubuwan da ya samo asali, beta-blockers, cimetidine, oxytetracycline, sulfanilamides, allopurinol, MAO inhibitors, phenylbutazone da abubuwansa, probenecid, chloramphenicol, salicylinone anionone, adadi mai yawa.
• Tasirin miyagun ƙwayoyi na iya raguwa lokacin amfani dashi tare da epinephrine, hormones thyroid, glucocorticoids, barbiturates, thiazide diuretics da maganin hana haihuwa.
• Tare da yin amfani da magunguna tare da magungunan shawo kan lokaci guda, haɓaka tasirin ƙarshen yana yiwuwa.
• Lokacin ɗauka tare da cimetidine, haɗarin haɓakar lactic acidosis yana ƙaruwa.

Farashi a cikin kantin magani

Farashin Glibomet don kunshin 1 yana farawa daga 280 rubles.

Bayyanar akan wannan shafin fasalin mai sauƙin fasalin hukuma na bayanin maganin. An bayar da bayanin ne don dalilai na ba da bayani kawai kuma ba jagora ba ne don maganin kansa.Kafin amfani da miyagun ƙwayoyi, dole ne ka nemi ƙwararren masani kuma ka san kanka tare da umarnin da masana'anta suka gindaya.