Diabefarm - umarnin don amfani

INGANTA
don amfani da magani

Lambar yin rijista:

Sunan kasuwanci: Diabefarm ®

Sunan kasa da kasa mai zaman kansa: gliclazide

Form sashi: allunan

Abun ciki:
Kwamfutar hannu 1 ya ƙunshi
Aiki mai aiki: gliclazide 80 MG
Fitowa: lactose monohydrate (sukari madara), povidone, magnesium stearate.

Bayanin
Allunan fararen kaya ko fari tare da tint mai launin shuɗi suna da silalliya tare da haɗarin chamfer da haɗari mai siffar giciye.

Rukunin Magunguna: wakili na hypoglycemic don sarrafawa na baka na gungun sulfonylurea na ƙarni na biyu

Lambar ATX: A10VB09

Aikin magunguna
Pharmacodynamics
Glyclazide yana ƙarfafa ƙwayar insulin ta hanyar ƙwayoyin panc-ƙwayoyin jiki, yana haɓaka tasirin insulin-secretory na glucose, kuma yana ƙara haɓaka kyallen takarda zuwa insulin. Yana ƙarfafa aikin enzymes na ciki - tsoka glycogen synthetase. Yana rage lokacin daga lokacin cin abinci zuwa farkon insulin insulin. Dawo da farkon gangar jikin rufin insulin (sabanin sauran abubuwan da ake amfani da su na sulfonylurea, wadanda suke da tasirin gaske a yayin aiki na biyu). Yana rage haɓakar postprandial a cikin glucose jini.
Bugu da ƙari ga shafar metabolism na metabolism, yana inganta microcirculation: yana rage haɗarin platelet da haɗuwa, yana daidaita ƙwayar jijiyoyin jiki, yana hana haɓakar microthrombosis da atherosclerosis, kuma yana dawo da tsarin aiwatar da fibrinolysis na ilimin halitta. Yana rage ji na jijiyoyin bugun zuciya zuwa adrenaline. Yana yin jinkirin haɓakar ciwon sikila a matakin fidda gwani. Tare da ciwon sukari mai narkewa tare da amfani da dogon lokaci, akwai raguwa sosai a cikin tsananin cutar proteinuria. Ba ya haifar da karuwa a cikin nauyin jiki, saboda yana da tasiri mai mahimmanci a farkon farkon ƙwayar insulin kuma ba ya haifar da hyperinsulinemia, yana taimakawa rage nauyin jiki a cikin marasa lafiya masu kiba tare da abincin da ya dace. Ya na da anti-atherogenic Properties, saukar da taro na jimlar cholesterol a cikin jini.
Pharmacokinetics
Bayan gudanar da baki, yana sha da sauri cikin hanji. Nuna rashin hankali yana da girma. Bayan gudanar da maganin baka na 80 mg, ana samun mafi girman yawan hankali a cikin jini (2.2-8 μg / ml) bayan kimanin sa'o'i 4, bayan gudanar da 40 MG, mafi girman taro a cikin jini (2-3 μg / ml) an kai shi bayan sa'o'i 2-3. tare da kariyar plasma - 85-97%, ƙarar rarraba - 0.35 l / kg. An sami daidaituwa a cikin jini bayan kwana 2. An metabolized a cikin hanta, tare da samuwar metabolites 8.
Yawan babban metabolite da aka samo a cikin jini shine kashi 2-3% na adadin maganin da aka ɗauka, ba shi da tasirin hypoglycemic, amma yana inganta microcirculation. Kwayar ta kwantar da ita - 70% a cikin hanyar metabolites, ƙasa da 1% a cikin hanyar da ba ta canzawa, ta hanyar hanji - 12% a cikin hanyar metabolites.
Rabin rayuwar shine awa 8 zuwa 20.

Alamu don amfani
Nau'in ciwon sukari na 2 na manya a cikin tsofaffi a haɗe tare da maganin rage cin abinci da motsa jiki na yau da kullun tare da ƙarshen baya tasiri.

Contraindications
Hypersensitivity ga miyagun ƙwayoyi, nau'in 1 mellitus na ciwon sukari, ketoacidosis masu ciwon sukari, precoa mai ciwon sukari, ciwon sukari, ƙwayar cutar hyperosmolar, hepatic mai tsanani da / ko gazawar koda, manyan ayyukan tiyata, ƙonewa mai yawa, raunin da sauran yanayin da ke buƙatar insulin farji, toshewar hanji, paresis ciki, yanayi hade da malabsorption abinci, haɓakar ƙarancin ƙwayoyin cuta (cututtukan cututtukan), leukopenia, ciki, shayarwa, yara ozrast zuwa shekaru 18.

Tare da kulawa (ana buƙatar kulawa da kulawa sosai da zaɓin sashi) an tsara shi don cututtukan febrile, cututtukan barasa da cututtukan thyroid (tare da aiki mai rauni).

Yi amfani da lokacin daukar ciki da lactation
An sanya kwayar cutar a lokacin daukar ciki da lokacin ciyarwa.
Lokacin da ciki ya faru, ya kamata a dakatar da miyagun ƙwayoyi nan da nan.

Sashi da gudanarwa
An saita kashi na miyagun ƙwayoyi daban-daban, gwargwadon shekarun mai haƙuri, alamun bayyanar cututtuka na cutar da matakin azumi glucose jini da sa'o'i 2 bayan cin abinci. Aikin yau da kullun shine 80 MG, matsakaici na yau da kullun shine 160 mg, kuma mafi girman kullun shine 320 mg. Ana shan Diabefarm a baki sau 2 a rana (safe da maraice) mintuna 30-60 kafin abinci.

Side sakamako
Hypoglycemia (idan akwai wani batun keta tsarin sashi da kuma rashin isasshen abinci): ciwon kai, gajiya, yunwar, gumi, rauni mai rauni, tashin hankali, damuwa, damuwa, rage yawan tunani da jinkirtawa, bacin rai, rauni na gani, rashin karfin jijiya, tashin hankali, tashin hankali, rashin damuwa , asarar iko da kai, rashin hankali, rashi, damuwa, rashin bacci, rashi mara nauyi, bradycardia.
Allergic halayen: itching, urticaria, maculopapular rash.
Daga gabobin hemopoietic: anaemia, thrombocytopenia, leukopenia.
Daga tsarin narkewa: dyspepsia (tashin zuciya, zawo, jin wani nauyi a cikin kwayar cutar hanji), anorexia - tsananin yana raguwa yayin ɗaukar abinci, ƙarancin aikin hanta (cholestatic jaundice, ƙara yawan aiki na “hanta” transaminases).

Yawan abin sama da ya kamata
Bayyanar cututtuka: hypoglycemia mai yiwuwa ne, har zuwa haɓakar ƙwaƙwalwar ƙwayar cuta.
Jiyya: idan mai haƙuri yana da hankali, ɗaukar carbohydrates (sukari) cikin sauƙi, tare da rikicewar hankali, ana gudanar da maganin 40% dextrose (glucose) a cikin ciki, 1-2 mg na glucagon intramuscularly. Bayan ya dawo cikin tunani, dole ne a bai wa mai haƙuri abincin da ke da wadataccen abinci mai narkewa a cikin ƙwayoyin cuta mai sauƙi (don guje wa sake haɓakawar hypoglycemia). Tare da edema na kwakwalwa, mannitol da dexamethasone.

Yin hulɗa tare da wasu kwayoyi
Angiotensin-canza enzyme inhibitors (captopril, enalapril), H2-histamine recepor blockers (cimetidine), magungunan antifungal (miconazole, fluconazole), magungunan anti-steroidal anti-mai kumburi (phenylbutazoflubrate, indigo), inhibitors na hypogabusilema (ethionamide), salicylates, coumarin anticoagulants, steroids anabolic, beta-blockers, cyclophosphamide, chloramphenicol, monoamine oxidase inhibitors, su fanilamidy tsawo mataki, fenfluramine, fluoxetine, pentoxifylline, guanethidine, theophylline, da kwayoyi da kuma toshe tubular mugunya, reserpine, bromocriptine, disopyramide, pyridoxine, allopurinol, ethanol da etanolsoderzhaschie shirye-shirye, kazalika da sauran hypoglycemic kwayoyi (acarbose, biguanides, insulin).
Weused the hypoglycemic effect of Diabefarma barbiturates, glucocorticosteroids, sympathomimetics (epinephrine, clonidine, ritodrine, salbutamol, terbutaline), phenytoin, jinkirin tashar alli, maganin carbonic anhydrase inhibitors, thiazide azolegegegegege , diazoxide, isoniazid, morphine, glucagon, rifampicin, hormones na thyroid, sinadarin lithium, a cikin manyan allurai - nicotinic acid, chlorpromazine, estrogens da maganin hana haihuwa na dauke da su.
Lokacin hulɗa tare da ethanol, amsa disulfiram-kamar zai yiwu.
Diabefarm yana ƙara haɗarin karin ventricular extrasystole yayin shan glycosides na zuciya.
Beta-blockers, clonidine, reserpine, guanethidine na iya rufe alamun bayyanar cututtuka na hypoglycemia.
Magungunan da ke hana haɓakar ƙwaƙwalwar ƙwayar tsoka suna haɓaka haɗarin myelosuppression.

Umarni na musamman
Ana aiwatar da aikin Diabefarm a hade tare da ƙarancin kalori, ƙarancin carb. Wajibi ne a lura da abubuwan glucose a cikin jini akai-akai a cikin komai a ciki kuma bayan cin abinci.
Game da maganin kutse ko kuma lalata cututtukan siga, ya zama dole a yi la’akari da yiwuwar amfani da shirye-shiryen insulin.
Wajibi ne a faɗakar da marasa lafiya game da karuwar haɗarin hypoglycemia dangane da shan ethanol, magungunan anti-mai kumburi, rashin abinci. Dangane da batun ethanol, yana kuma yiwuwa a samar da wata cuta ta disulfiram kamar (ciwon ciki, tashin zuciya, amai, ciwon kai).
Wajibi ne don daidaita yawan maganin tare da wucewar jiki ko tunanin mutum, canjin abinci
Musamman kula da aikin hypoglycemic kwayoyi tsofaffi ne, marasa lafiya waɗanda ba su karɓar abinci mai daidaita, marasa lafiya masu rauni, marasa lafiya da ke fama da rashin isasshen ƙwayar cuta ta jiki.
A farkon farawar magani, yayin zaɓin kashi, marasa lafiya da ke ci gaba da haɓaka ƙarancin hypoglycemia ba a ba da shawarar su shiga cikin ayyukan buƙatar buƙatar hankali da saurin halayen psychomotor ba.

Fom ɗin saki
Allunan kwayoyi 80
A kan allunan 10 a cikin marfin ruwan tabarau daga fim na polyvinyl chloride da kuma allon fitilun aluminium da aka buga.
3 ko 6 murhun ciki tare da umarnin don amfani ana sanya su a cikin fakitin kwali.

Yanayin ajiya
Lissafi B. A cikin busasshiyar wuri, duhu mai yawan zafin jiki wanda bai wuce 25 ° C ba.
Ayi nesa da isar yara.

Ranar karewa
Shekaru 2
Kada kayi amfani bayan ranar karewa.

Sharuɗɗan hutu na kantin
Da takardar sayan magani.

Ya kamata a magance abubuwan da suka shafi masana'anta:
FARMAKOR Production LLC, Rasha
Adireshin samarwa:
198216, St. Petersburg, Leninsky Prospect, d.140, lit. F
Adireshin shari'a:
194021, St. Petersburg, Muryarky na Muryarky na 2, 41, lit. A