Yaushe da Yadda ake Shan Galvus, Maganin Ciwon Ciwon Ciwon Kai

Galvus magani ne ga ciwon sukari, abu mai aiki wanda shine vildagliptin, daga ƙungiyar Dhib-4 inhibitors. An yi rajistar allunan ciwon sukari na Galvus a Rasha tun daga 2009. Suna samar da Novartis Pharma (Switzerland).

Allunan Galvus don kamuwa da cuta daga ƙungiyar masu hana DPP-4 - abu mai aiki mai suna Vildagliptin

An yi rajista Galvus don kula da marasa lafiya da ke dauke da ciwon sukari na 2. Ana iya amfani dashi azaman magani guda ɗaya, kuma tasirinsa zai cika sakamakon abinci da motsa jiki. Hakanan za'a iya amfani da kwayoyin cutar ciwon sukari na Galvus a hade tare da:

• metformin (siofor, glucophage),
• Sinadarin sulfonylurea (ba bukatar yin wannan!),
• saozamari,
• insulin

Galvus Allunan sashi

Matsakaicin adadin Galvus a matsayin monotherapy ko tare da haɗin kai tare da metformin, thiazolinediones ko insulin - sau 2 a rana, 50 MG, safe da maraice, ba tare da la'akari da yawan abinci ba. Idan an tsara mai haƙuri akan kwayar 1 of 50 MG a rana, to dole ne a sha da safe.

Vildagliptin - kayan aiki na miyagun ƙwayoyi don ciwon sukari Galvus - kodan ya keɓe shi, amma a cikin yanayin metabolites marasa aiki. Sabili da haka, a matakin farko na cin nasara na koda, ba a buƙatar canza sashi na maganin ba.

Idan akwai mummunan keta ayyukan hanta (ALT ko enzymes enzymes 2.5 sau sama da babba na al'ada), to ya kamata a tsara Galvus da taka tsantsan. Idan mai haƙuri ya bunkasa jaundice ko wasu gunaguni na hanta sun bayyana, ya kamata a dakatar da maganin ta vildagliptin nan da nan.

Ga masu fama da cutar siga masu shekaru 65 da haihuwa - kuma kashi na Galvus baya canzawa idan babu maganin cutar kwalliya. Babu bayanai game da amfani da wannan maganin cutar siga a yara da matasa masu shekaru 18 da haihuwa. Sabili da haka, ba a ba da shawarar yin shi ga marasa lafiya na wannan rukunin na wannan zamani ba.

Rage tasirin sukari na vildagliptin

An yi nazarin tasirin rage sukari na vildagliptin a cikin rukuni na marasa lafiya 354. Ya juya ga cewa monotherapy na galvus cikin makonni 24 ya haifar da raguwar yawan glucose na jini a cikin waɗannan marasa lafiyar da basu taɓa yin maganin ciwon sukari na 2 ba. Gididdigar haemoglobin su ta ragu da 0.4-0.8%, kuma a cikin ƙungiyar placebo - da 0.1%.

Wani binciken ya kwatanta tasirin vildagliptin da metformin, shahararrun magungunan cutar sankara (siofor, glucophage). Wannan binciken ya haɗa da marasa lafiya waɗanda kwanan nan sun kamu da cutar sukari ta 2, kuma ba a yi musu magani ba kafin.

Ya juya ya nuna cewa galvus a cikin yawancin alamu na aikin ba ƙasa da metformin ba. Bayan makonni 52 (shekara ɗaya na jiyya) a cikin marasa lafiya suna shan galvus, matakin glycated hemoglobin ya ragu da matsakaicin 1.0%. A cikin ƙungiyar metformin, an rage shi da 1.4%. Bayan shekaru 2, lambobin sun kasance iri ɗaya.

Bayan makonni 52 na shan allunan, ya juya cewa yanayin ƙarfin nauyin jikin a cikin marasa lafiya a cikin rukunin vildagliptin da metformin kusan iri ɗaya ne.

Mafi kyawun haƙuri ana yarda da Galvus fiye da metformin (Siofor). Sakamakon sakamako na jijiyoyi a cikin jijiyoyi na ciki suna ci gaba da yawaita akai-akai. Saboda haka, kayan hukuma na Rashanci na zamani da aka yarda da su don maganin cututtukan type 2 na ciwon sukari suna ba ku damar fara jiyya tare da galvus, tare da metformin.

Hanyar Galvus: vildagliptin + haɗuwa metformin

Galvus Met shine magani mai haɗuwa wanda ya ƙunshi 1 kwamfutar hannu na vildagliptin a kashi 50 MG da metformin a allurai na 500, 850 ko 1000 mg. Rajista a Rasha a cikin Maris 2009. An ba da shawarar yin shi ga marasa lafiya 1 kwamfutar hannu 1 sau 2 a rana.

Galvus Met shine magani na haɗuwa don nau'in ciwon sukari na 2. Ya ƙunshi vildagliptin da metformin. Abubuwa biyu masu aiki a cikin kwamfutar hannu guda ɗaya - dace don amfani da tasiri.

Haɗin vildagliptin da metformin ana ɗauka sun dace don lura da ciwon sukari na 2 a cikin marasa lafiya waɗanda ba su shan metformin kaɗai. Amfaninta:

• Sakamakon rage yawan matakan glucose na jini yana ƙaruwa, idan aka kwatanta da monotherapy tare da kowane daga cikin kwayoyi,
• Ragowar aikin kwayoyin sel a cikin samar da insulin ana kiyaye su,
• nauyin jiki a cikin marassa lafiya baya karuwa,
• haɗarin hauhawar jini, ciki har da mai tsanani, baya ƙaruwa,
• yawan tasirin sakamako na metformin daga ƙwayar gastrointestinal - ya kasance a daidai wannan matakin, baya ƙaruwa.

Nazarin ya tabbatar da cewa shan Galvus Met yana da tasiri kamar ɗaukar allunan guda biyu daban-daban tare da metformin da vildagliptin. Amma idan kuna buƙatar ɗaukar kwamfutar hannu guda ɗaya kawai, to, ya fi dacewa kuma magani ya fi tasiri. Domin yana da ƙarancin cewa mai haƙuri zai manta ko ya rikitar da wani abu.

An gudanar da bincike - idan aka kwatanta da lura da ciwon sukari tare da Galvus Met tare da wani makirci na yau da kullun: metformin + sulfonylureas. An sanya magungunan Sulfonylureas ga marasa lafiya da ciwon sukari waɗanda suka gano Metformin kadai bai isa ba.

Nazarin ya kasance babba-sikeli. Fiye da marasa lafiya 1300 a cikin rukuni biyu sun halarci wannan. Tsawon Lokaci - shekara 1. Ya juya cewa a cikin marasa lafiya suna shan vildagliptin (50 mg sau 2 a rana) tare da metformin, matakan glucose na jini sun ragu har ma da waɗanda suka dauki glimepiride (6 mg 1 lokaci ɗaya kowace rana).

Babu wani bambance-bambance masu mahimmanci a cikin sakamako don rage yawan sukari na jini. A lokaci guda, marasa lafiya a cikin rukuni na miyagun ƙwayoyi na Galvus Met sun ɗanɗano jinin hailawa sau 10 ƙasa da waɗanda ba a kula da su tare da glimepiride tare da metformin. Babu wani lamunin rashin lafiya mai tsanani a cikin marasa lafiya da ke shan Galvus Met na tsawon shekara.

Yadda ake Amfani da Magungunan Ciwon Ciwon Galvus Tare da insulin

Galvus shine magani na farko na ciwon sukari daga ƙungiyar inhibitor DPP-4, wanda aka yiwa rajista don haɗuwa da insulin. A matsayinka na mai mulkin, an wajabta shi idan ba zai yiwu a sarrafa nau'in ciwon sukari guda 2 da kyau tare da maganin basal kadai ba, wato, “insulin” tsawo.

Nazarin 2007 ya kimanta inganci da amincin ƙara galvus (50 mg sau 2 a rana) a kan placebo. Marasa lafiya sun halarci waɗanda suka kasance a cikin matakan hawan jini mai haɓaka (7.5-1%) a kan injections na “matsakaici” insulin tare da tsaka tsaki na Hagedorn protramine (NPH) a sashi na sama da raka'a 30 a rana.

Marasa lafiya 144 sun karɓi galvus tare da allurar insulin, marasa lafiya 152 da ke da nau'in ciwon sukari na 2 sun karɓi placebo a tushen allurar insulin. A cikin rukunin vildagliptin, matsakaicin matakin gemoclobin hemoglobin ya ragu da 0,5%. A cikin rukunin placebo, da kashi 0.2%. A cikin marasa lafiya da suka girmi shekaru 65, alamu sunfi kyau - ragin 0.7% akan asalin galvus da 0.1% a sakamakon shan placebo.

Bayan ƙara galvus zuwa insulin, haɗarin hypoglycemia yana raguwa sosai, idan aka kwatanta da maganin cututtukan ƙwayar cuta, injections na "matsakaici" NPH-insulin. A cikin rukunin vildagliptin, jimlar adadin hypoglycemia ya kasance 113, a cikin rukunin placebo - 185. Bugu da ƙari, ba a lura da yanayin guda ɗaya na mummunan hypoglycemia ba yayin lura tare da vildagliptin. Akwai 6 irin wannan aukuwa a cikin kungiyar placebo.

Abun haɗin da kaddarorin allunan

Allunan ciki na allunan sune kamar haka abubuwan da aka gyara:

• babban bangaren shine vildagliptin,
• abubuwa masu taimako - cellulose, lactose, sitaci carboxymethyl sitaci, stenes magnesium.

Magungunan yana da masu zuwa kaddarorin:

• inganta aikin cututtukan zuciya,
• yana haifar da raguwa a cikin juriya na insulin saboda haɓakar ayyukan ƙwayoyin ƙwayar ƙwayar cuta mai lalacewa,
• yana rage yawan cutarwa a cikin jini.

Tasiri a jiki

Magungunan yana da tasiri mai kyau a jikin mai haƙuri. A lokuta da wuya, ana lura da mummunan sakamako masu illa. Magungunan yana ba ka damar sarrafa sukari na jini saboda keɓaɓɓen abun da ya ƙunsa da kaddarorin. Yana haɓaka ayyukan ƙwayar ƙwayar tsoka da enzymes waɗanda ke haɗuwa da ƙwayar glucose.

Magungunan yana inganta yanayin mai haƙuri kuma wannan sakamakon ya ci gaba na dogon lokaci. Tasirin maganin shine awanni 24.

Drawace da miyagun ƙwayoyi yawanci yana faruwa ne tare da taimakon kodan, ƙasa da yawa ta hanyar narkewa.

Yaya ake nema?

Magungunan "Galvus" an nuna shi ga nau'in ciwon sukari na 2. An umurce miyagun ƙwayoyi don ɗayan kwamfutar hannu guda ɗaya kowace safiya, ko kwamfutar hannu ɗaya sau biyu a rana (safe da maraice). Babu wani bambanci game da amfani da miyagun ƙwayoyi kafin abinci ko bayan. Yanayin amfani da "Galvus" dole ne a zaɓi shi daban-daban, la'akari da lokacin inganci da haƙuri.

Aiwatar da maganin a baka, yayin shan kwaya tare da isasshen ruwa. Sashi na miyagun ƙwayoyi kada ya wuce 100 MG kowace rana.

Ana amfani da miyagun ƙwayoyi "Galvus" azaman:

• monotherapy, haɗuwa tare da abinci kuma ba mai ƙarfi ba, amma aiki na yau da kullun (watau, kawai "Galvus" + abinci + wasanni),
• farawa na ciwon sukari a hade tare da maganin rage sukari na Metformin, lokacin da abincin da motsa jiki kadai basu bada sakamako mai kyau (watau, "Galvus" + Metformin + abinci + wasanni),
• hadaddun magani tare da magunguna masu rage sukari ko insulin, idan abinci, motsa jiki da magani tare da Metformin / insulin kadai ba su taimaka (watau, “Galvus” + Metformin ko kayan abinci na sulfonylurea, ko thiazolidinedione, ko insulin + abinci + motsa jiki),
• haɗuwa tare da magani: Abubuwan da suka samo asali na sulfonylurea + Metformin + "Galvus" + abincin abinci + ilimin jiki, lokacin da magani iri ɗaya, amma ba tare da "Galvus" ba ya aiki,
• haɗakar magani: Metformin + insulin + Galvus, lokacin da aka yi amfani da wannan magani a baya, amma ba tare da Galvus ba, ba ta samar da tasirin da ake tsammanin ba.

Masu ciwon sukari suna amfani da wannan magani yawanci a sashi:

• monotherapy - 50 mg / rana (da safe) ko 100 MG / rana (i.e. 50 mg da safe da maraice),
• Metformin + "Galvus" - 50 MG 1 ko sau 2 a rana,
• Sinadarin sulfonylurea + “Galvus” - 50 mg / rana (1 a kowace rana, da safe),
• thiazolidinedione / insulin (wani abu daya daga cikin jerin) + “Galvus” - 50 MG 1 ko sau 2 a rana,
• Abubuwan sulfonylurea + Metformin + Galvus - 100 MG / rana (watau sau 2 a rana, 50 MG, safe da maraice),
• Metformin + insulin + "Galvus" - 50 MG 1 ko sau 2 a rana.

Lokacin ɗaukar "Galvus" tare da shirye-shiryen sulfonylurea, kashi na ƙarshen dole ragedon hana haɓakar hauhawar jini!

Zai fi dacewa, lokacin shan maganin sau biyu a rana, kuna buƙatar shan wani kwaya sa'o'i 12 bayan na baya. Misali, da karfe 8 na safe sun dauki kwamfutar hannu 1 (50 MG) kuma a ƙarfe 8 na dare sun ɗauki kwamfutar hannu 1 (50 MG). A sakamakon haka, an dauki 100 MG na magani a kowace rana.

Ana ɗaukar kashi 50 na MG a lokaci, ba a rarrabuwa zuwa kashi biyu.

Idan wannan sashi ba ya bayar da sakamako mai kyau, duk da rikitacciyar farjin, to lallai ya zama dole a ƙara wasu kwayoyi ban da shi, amma ba shi yiwuwa a ƙara sashi na "Galvus" akan 100 MG / rana!

Masu ciwon sukari waɗanda ke fama da cututtuka masu laushi na cututtukan cututtukan ƙwayoyin cuta na jiki (i.e., koda da hanta) galibi suna amfani da sashi na 50 MG. Mutanen da ke da raunin nakasa (koda kuwa suna da wata cuta ta koda ko cutar hanta), Galvus, a matsayin mai mulkin, ba a tsara shi ba.

A cikin tsofaffi (daga shekaru 60 ko fiye), sashi na wannan magani daidai yake da na samari. Amma har yanzu, mafi yawan lokuta, ana tsara tsofaffi don ɗaukar 50 MG sau ɗaya a rana.

A kowane hali, ya kamata a yi amfani da miyagun ƙwayoyi "Galvus" kawai a ƙarƙashin kulawa na likita.

Matasa nau'in masu ciwon sukari guda 2, i.e. yara da matasa masu shekaru masu shekaru bai kamata su sha wannan maganin ba, tunda ba a gwada shi ba a wannan rukunin mutane na mutane yayin gwaji na asibiti.

Mata masu ɗaukar tayi ba da shawarar yin amfani da wannan magani ba. Madadin haka, yana iya amfani da magungunan hormonal na al'ada (i.e. insulin).

Koyaya, kwarewar sirri na likitocin ya nuna cewa babu wani mummunan sakamako game da ci gaban ciki a cikin kashi 50 na MG kowace rana, amma har yanzu yana da kyau mu guji amfani da wannan magani idan ya yiwu. Don haka, yin amfani da "Galvus" ta hanyar iyaye mata masu yiwuwa har yanzu yana yiwuwa, amma tare da shawarar kwararru.

Hakanan ana ba da shawarar dakatar da shan miyagun ƙwayoyi yayin shayarwa, tun da babu wanda ya san ko abu mai aiki ya shiga cikin madara ko a'a.

Mai yiwuwa contraindications

Kamar sauran kwayoyi, yana da maganin sa. Ainihin, koda kuwa wasu abubuwan da ba a so sun bayyana, sun kasance na ɗan lokaci ne kuma sun ɓace bayan wani lokaci, don haka ba a samar da canjin daga wannan magani zuwa kowane ba.

Contraindications na wannan magani sune kamar haka:

1. Mahimmanci mahaukaci a cikin aikin koda, hanta da / ko zuciya.
2. Metabolic acidosis, ketoacidosis masu ciwon sukari, lactic acidosis, ƙwayar cutar sukari.
3. Type 1 ciwon sukari.
4. Ciki da shayarwa.
5. Shekarun yara.
6. Allergy zuwa ɗaya ko fiye da aka gyara na miyagun ƙwayoyi.
7. Yin haƙuri
8. Rashin bacci.
9. Rashin narkewar ƙwayar cuta da kuma shan glukos-galactose.
10. Increasedarin darajar enzymes na hepatic (ALT da AST) a cikin jini.

Tare da taka tsantsan, yakamata a yi amfani da miyagun ƙwayoyi "Galvus" don mutanen da ƙila su kamu da cututtukan pancreatitis.

Side effects

Abubuwan da ke haifar da sakamako sukan haifar da yawan shan magani:

• farin ciki, ciwon kai,
• rawar jiki
• jin sanyi
• tashin zuciya, amai,
• mawakwalwa na ciki,
• zawo, maƙarƙashiya, ƙwanƙwasa,
• hawan jini,
• hyperhidrosis
• rage aiki da gajiya,
• na gefe harshe,
• nauyi.

Magungunan "Galvus" an nuna shi ga nau'in ciwon sukari na 2. Kayan aiki yana da fasali a amfani da sashi. Magungunan yana da tasiri mai kyau a jiki, yana daidaita matakin sukari a cikin tsarin wurare dabam dabam. Kayan aiki yana da sakamako masu illa da contraindications, don haka ya kamata wasu mutane suyi amfani da shi a hankali.

Aikace-aikacen

Galvus magani ne da ke daidaita yanayin sukari a jiki. Ana ɗaukar shi gabaɗaya ta bakin. Wannan magani yana haɓaka ji na jijiyoyin jiki ga glucose, wanda ke taimaka wa insulin fita.

Vildagliptin abu ne wanda ke cikin ƙwayoyi. Yana taimakawa wajen kula da ƙwayoyin beta na yau da kullun.

Idan mutum ba shi da ciwon sukari, to magungunan ba su bayar da gudummawa ga sakin insulin ba kuma bai canza matakin glucose a cikin tsarin jijiyoyin jini ba.

Galvus na iya haifar da ƙananan matakan lipids a cikin tsarin wurare dabam dabam. Ba a sarrafa wannan tasiri ta hanyar canje-canje a cikin aikin ƙwayoyin ƙwayoyin cuta.

Galvus na iya rage motsin hanji. Wannan aikin ba shi da alaƙa da amfani da vildagliptin.

Met Galvus Met wani nau'in magani ne. Baya ga vildagliptin, ya ƙunshi metformin mai aiki.

Babban alamomi na shan ƙwayoyi don nau'in ciwon sukari na 2 na sukari:

• Don monotherapy, hada tare da abinci da ingantaccen aikin jiki.
• Marasa lafiya waɗanda suka yi amfani da magunguna waɗanda a baya suke amfani da metformin a gaba ɗayansu.
• Don monotherapy, haɗuwa tare da metformin. Ana amfani dashi idan aikin jiki da abinci ba su kawo sakamakon da ake so ba.
• A matsayin ƙari ga ilimin insulin.
• Rashin nasarar hade magani. A wasu halaye, ana ba shi izinin ɗaukar insulin, metformin da vildagliptin tare.

Vildagliptin, idan an ɗauka akan komai a ciki, jiki yana ɗaukar hanzari. Lokacin cin abinci, yawan sha yana raguwa. Vildagliptin, kasancewa cikin jiki, ya juya zuwa metabolites, bayan hakan ya fita daga ruwa na urinary.

Umarnin Galvus meth don amfani yana nuna cewa jima'i da nauyin jikin mutum ba su shafar kayan aikin magani na vildagliptin.Ba a gudanar da nazarin da ke iya gano tasirin vildagliptin kan yara 'yan ƙasa da shekaru 18 ba.

Metformin, yana cikin Galvus Met, yana rage yawan ƙwayar magunguna saboda cin abinci. Abun da wuya yayi hulɗa da jini. Metformin na iya shiga cikin sel jini, sakamako yana ƙaruwa tare da tsawan amfani da magani. Kodan kusan kodan ta cire kayan ta, ba tare da ta canza kamannin ta ba. Bile da metabolites ba a kafa su ba.

Babu wani binciken da aka gudanar wanda ya nuna sakamakon Galvus akan jikin mace mai ciki. Ba'a ba da shawarar shan maganin ba yayin wannan lokacin (an maye gurbinsu da ilimin insulin).

Umarnin don amfani

Ana amfani da Galvus ta baki kawai. Lokacin cin abinci ba lallai ba ne. Allunan ba su tauna ba, an sha su da ruwa sosai.

Lokacin shan kwayoyi, ya kamata a kula da kulawa ta musamman ga hulɗa da miyagun ƙwayoyi:

• Vildagliptin tare da metformin. Lokacin ɗaukar abubuwan biyu a cikin allurai masu karɓa, ba a gano ƙarin sakamako ba. Vildagliptin kusan ba sa hulɗa tare da wasu kwayoyi. Ba'a amfani dashi tare da hanawa. Tasirin vildagliptin a jikin mutum tare da sauran magunguna da aka tsara don nau'in ciwon sukari na II ba a kafa ba. Ya kamata a yi taka tsantsan.
• Metformin. Idan aka ɗauke shi tare da Nifedipine, to, ƙwaƙwalwar metformin tana ƙaruwa. Metformin kusan ba shi da tasiri a cikin kadarorin Nifedipine. Glibenclamide, a hade tare da abu, ya kamata a ɗauka a hankali: sakamakon na iya bambanta.

Ya kamata a ɗauki Galvus a hankali tare da kwayoyi waɗanda ke shafar aikin koda.

Amfani da Galvus da chlorpromazine ba da shawarar ba. Saboda wannan, an rage matakan insulin insulin. Ana buƙatar gyaran sashi.

Haramun ne a sha magungunan da ke dauke da ethanol tare da Galvus. Wannan yana haifar da damar lactic acidosis. Hakanan ya zama dole a guji shan duk wata giya.

Contraindications

Galvus yana da yawan gaske contraindications:

• Paarancin aiki na haya, gazawar renal.
• Cututtuka da yanayi waɗanda zasu iya haifar da nakasa aiki na koda. Daga cikin wadannan, bushewar zazzabi, zazzabi, cututtuka, da karancin iskar oxygen a jiki sun fice.
• Cututtukan zuciya, infarin zuciya.
• Rashin lafiyar tsarin numfashi.
• Rashin hanta.
• M ko matsa lamba na ma'aunin acid-base balance. A cikin wannan halin, ana amfani da maganin insulin.
• Ba'a amfani da miyagun ƙwayoyi kwana 2 kafin tiyata ko gwaje-gwaje. Hakanan, kar a dauki farkon kwanaki 2 bayan hanyoyin.
• Type 1 ciwon sukari.
• Yawan shan giya da dogaro da shi. Cutar ciwon ciki
• Cin abinci kaɗan. Matsakaicin ƙa'idar shan magani shine adadin kuzari 1000 kowace rana.
• Rashin hankali ga kowane abu mai dauke da maganin. Ana iya maye gurbin shi da insulin, amma bayan tuntuɓar ƙwararrun masani.

Babu bayanai game da shan maganin yayin daukar ciki da kuma lactation. Yi amfani da maganin yana contraindicated. Hadarin ƙarancin ciki a cikin ɗan da ba a haifa ba na iya ƙaruwa. Sauya maganin tare da maganin insulin an bada shawarar.

Maganin yana contraindicated a cikin yara a karkashin balagagge. Ba a gudanar da bincike kan wannan rukunin mutane ba.

Dole ne a yi amfani da miyagun ƙwayoyi tare da taka tsantsan ga mutanen da suka wuce shekaru 60 da haihuwa. Ana buƙatar kulawa da kulawa na likita a duk lokacin karatun.

Ana yin allurai na Galvus daban-daban ga kowane mara lafiya. Ya dogara da haƙurin jiki da sauran kwayoyi da ake amfani da su don maganin taɓin hankali.

Sashin maganin da aka yi amfani dashi don monotherapy tare da insulin daga 0.05 zuwa 0.1 g na abu mai aiki yau da kullun. Idan mai haƙuri yana fama da mummunan nau'in ciwon sukari, ana bada shawara don fara shan maganin tare da 0.1 g.

Idan tare ana amfani da Galvus ƙarin shirye-shirye biyu na kusa, to sashi yana farawa da 0.1 g kowace rana. Ya kamata a dauki kashi 0.05 g a lokaci guda. Idan kashi ya kasance 0.1 g, to dole ne ya shimfiɗa a cikin allurai 2: safe da maraice.

Tare da monotherapy, tare da shirye-shiryen sulfonylurea, sashi da ake so shine 0.05 g kowace rana. Ba'a bada shawara don ɗaukar ƙari ba: dangane da nazarin asibiti, an gano cewa matakan 0.05 g da 0.1 g a zahiri basu bambanta da tasiri. Idan ba'a sami sakamako na magani da ake so ba, to za a bada izinin sashi na 0.1 g da wasu kwayoyi waɗanda ke rage sukarin jini.

Idan mai haƙuri yana da ƙananan matsaloli tare da aikin koda, to, daidaitawar sashi ba lallai ba ne. Ya kamata a rage magungunan zuwa 0.05 g a lokuta inda akwai manyan matsalolin koda.

Bari mu matsa zuwa kan la’akari da magunguna don maganin Galvus Met.

Dosages aka zaɓi daban-daban ga kowane haƙuri. Ba'a ba shi izinin wuce matsakaicin matsakaicin yau da kullun na abu mai aiki ba - 0.1 g.

Idan magani tare da Galvus na al'ada bai kawo sakamakon da ake so ba, to ya kamata ya fara da 0.05 g / 0.5 g .. Waɗannan sune vildagliptin da metformin, bi da bi. Dos na iya ƙara girma bisa la'akari da kimantawar tasirin magani. Idan metformin bai ba da sakamako mai mahimmanci a cikin jiyya ba, to, ɗauki Galvus Met a cikin waɗannan matakan: 0.05 g / 0,5 g, 0.05 g / 0.85 g ko 0.05 g / 1 g. Ya kamata a raba liyafar zuwa 2 sau.

Sigar farko don marasa lafiya waɗanda tuni an kula dasu da metformin da vildagliptin sun dogara da halayen mutum na aikin maganin. Waɗannan suna iya zama allurai masu zuwa: 0.05 g / 0.5 g, 0.05 g / 0.85 g ko 0.05 g / 1 g .. Idan magani tare da tsarin abinci da daidaituwar salon rayuwa ba su fitar da sakamako ba, to, maganin ƙwayoyi ya kamata farawa da 0.05 g / 0.5 g, an dauki 1 lokaci. A hankali, yakamata a ƙara yawan zuwa 0.05 g / 1 g.

A cikin tsofaffi, yawanci ana lura da raguwar aikin koda. A irin waɗannan halayen, kuna buƙatar ɗaukar mafi ƙarancin ƙwayoyi, wanda zai iya sarrafa matakin sukari. Wajibi ne a gudanar da gwaje-gwaje a koyaushe wanda ke bayyana halin da kodan ke ciki.

• Allunan Galvus na 0.05 g na kayan aiki masu aiki za'a iya sayansu don 814 rubles.
• Galvus Met, farashin kusan 1,500 rubles ne ga allunan 30 tare da abubuwan daban-daban na metformin da vildagliptin. Don haka, alal misali, galvus meth 50 mg / 1000 mg zai biya 1506 rubles.

Duk magunguna biyu ne takardar sayen magani.

Yi la'akari da kwayoyi waɗanda suke maye gurbin Galvus:

• Arfezetin. Amfani da shi azaman warke don masu ciwon sukari. Ga cikakken magani bai dace ba. Kusan babu sakamako masu illa, ana iya amfani dashi don monotherapy. Amfanin shine ƙananan farashi - 69 rubles. An saya ba tare da takardar sayan magani ba.
• Victoza. Magunguna masu tsada da tasiri. Ya ƙunshi liraglutide a cikin kayanta. Akwai shi a cikin nau'in sirinji. Farashin - 9500 rub.
• Glibenclamide. Yana inganta sakin insulin. Ya ƙunshi glibenclamide mai aiki a cikin abubuwan da ya ƙunsa. Kuna iya siyar da takardar sayan magani don 101 rubles.
• Glibomet. Yana taimakawa wajen daidaita sukarin jini da matakan insulin. Za'a iya siyan allunan 20 na miyagun ƙwayoyi don 345 rubles.
• Glidiab. Abunda yake aiki shine gliclazide. Sensara ji daɗin ji ga insulin. Bambanci a cikin farashi mai araha da inganci. Za'a iya siyan magungunan don 128 rubles. - Allunan 60.
• Gliformin. Abubuwan da ke aiki shine metformin. Yana da karancin sakamako. Farashin - 126 rubles don allunan 60.
• Glucophage. Ya ƙunshi hydrochloride metformin. Ba ya motsa samar da insulin. Ana iya siyan shi don 127 rubles.
• Galvus. Inganta glycemic iko. Yana da wuya a samu a cikin magunguna na Rasha, kuma musamman St. Petersburg.
• Glucophage Tsayi. Guda ɗaya kamar wanda ya gabata. Bambanci kawai shine jinkirin sakin abubuwa. Farashin - 279 rub.
• Mai ciwon sukari. Yana rage adadin sukari a cikin tsarin jijiya. Amfani da rashin daidaituwa na tsarin abinci mai gina jiki. Farashin 30 Allunan shine 296 rubles.
• Maninil. Ya ƙunshi glibenclamide. Ana iya amfani dashi azaman wani ɓangaren monotherapy. Farashin shine 118 rubles. na allunan 120.
• Metformin. Yana saurin aiwatar da samuwar glycogen. Yana haɓaka ƙwayar tsoka. Sanar da takardar sayan magani Farashin - 103 rubles. na allunan 60.
• Siofor. Ya ƙunshi metformin. Yana rage samarda glucose, yana kara yawan insulin. Ana iya amfani dashi don monotherapy. Matsakaicin matsakaici shine 244 rubles.
• Kayan tsari. Yana rage gluconeogenesis kuma yana kara haɓakar jijiyoyin jiki zuwa insulin. Ba ya bayar da gudummawa ga samar da insulin. Kuna iya siye don 85 rubles.
• Januvius. Ya ƙunshi sitagliptin mai aiki. Ana iya amfani dashi azaman wani ɓangaren monotherapy. An samo shi don 1594 rubles.

Waɗannan su ne mafi mashahuri Galvus da Galvus Met analogues. Ba a yarda da canji mai zaman kanta daga wannan magani zuwa wata ba. Ana buƙatar shawara tare da gwani.

Yawan abin sama da ya kamata

Yawan shaye-shaye na vildagliptin yana faruwa lokacin da aka kara adadin zuwa 0.4 g. A wannan yanayin, ana lura da masu zuwa:

• Jin zafi a cikin tsokoki.
• Yanayin Fabrairu.
• Kwari.

Jiyya ta ƙunshi cikakkiyar kin amincewa da miyagun ƙwayoyi na ɗan lokaci. Ba a yi amfani da faɗakarwa ba. Hakanan, magani na iya zama alama.

Yawan overform na metformin yana faruwa tare da yin amfani da fiye da 50 g na abu. A wannan yanayin, ana iya lura da hypoglycemia da lactic acidosis. Babban bayyanar cututtuka:

• Zawo gudawa
• Temperaturearancin zafin jiki.
• Jin zafi a ciki.

A irin waɗannan halayen, wajibi ne don barin miyagun ƙwayoyi. Don magani, ana amfani da hemodialysis.

Yi la'akari da sake dubawa da mutane ke barin game da Galvus ko Galvus Met:

Nazarin Galvus suna ba da shawarar cewa wannan kyakkyawar dama ce don sarrafa sukari. Mutanen da suke amfani da maganin suna lura da tasirin sa.

Side effects

Gabaɗaya, galvus magani ne mai lafiya. Nazarin sun tabbatar da cewa magani ga masu ciwon sukari na nau'in 2 tare da wannan magani baya kara hadarin cutar cututtukan zuciya, matsalolin hanta, ko raunin tsarin garkuwar jiki. Shan vildagliptin (kayan aiki mai aiki a cikin allunan galvus) baya kara nauyi a jiki.

Idan aka kwatanta da wakilai masu saukar da jini na gargajiya na gargajiya, kazalika da placebo, galvus baya kara hadarin cututtukan farji. Yawancin illolin da ke tattare da ita suna da laushi da wucin gadi Da wuya a lura:

• aikin hanta mai rauni (gami da hepatitis),
• angioedema.

Halin wadannan sakamako masu illa shine daga 1/1000 zuwa 1/10 000 marasa lafiya.