Wasu gumaka suna kara hadarin kamuwa da ciwon suga.

Wasu gumakan da aka saba amfani dasu don rage cholesterol na iya kara hadarin kamuwa da ciwon sukari na 2. A cikin bincike kan wannan batun, an lura cewa hadarin kamuwa da cutar siga ya fi ƙaruwa yayin shan magunguna kamar atorvastatin (Lipitor alamar kasuwanci), rosuvastatin (Crestor) da simvastatin (Zocor). An buga sakamakon binciken a cikin jaridar BMJ.

Ta hanyar mai da hankali kan mazaunan yankin 500,000 na Ontario, Kanada, masu binciken sun kammala da cewa kusan gaba ɗaya ana samun ci gaban masu ciwon sukari a cikin marasa lafiya ta hanyar amfani da jerin gwanon mutum. Koyaya, mutanen da suke shan atorvastatin suna da haɗarin 22% na kamuwa da cutar sankara, rosuvastatin 18% mafi girma, kuma simvastatin 10% sunfi waɗanda ke shan pravastol, magani ne A cewar likitocin, tasiri mafi tasiri ga mutanen da ke fama da ciwon sukari.

Masu binciken sunyi imanin cewa lokacin da suke rubuta waɗannan magunguna, likitoci ya kamata suyi la’akari da duk haɗarin da fa'ida. Wannan baya nufin cewa mara lafiya ya kamata su daina ɗaukar siffofin gaba ɗaya, ƙari, nazarin halayen bai samar da tabbataccen tabbaci game da alaƙar alaƙa tsakanin shan waɗannan magungunan da ci gaban cutar ba.

"Wannan binciken, wanda ke nufin tantance alaƙar da ke tsakanin amfani da statin da kuma haɗarin kamuwa da ciwon sukari, yana da matsaloli da yawa waɗanda ke ba da wuya a taƙaita sakamakon," in ji Dokta Dara Cohen, farfesa na Medicine a Cibiyar Kiwon Lafiya na Mount (New York). "Wannan binciken bai yi la'akari da nauyi ba, kabilanci, da kuma tarihin dangi, waɗanda ke da mahimman haɗarin haɗari ga ciwon sukari."

A cikin ra'ayoyin masu rakiyar, likitocin Finnish sun rubuta cewa yiwuwar bayanan haɗarin kada ya ƙarfafa mutane su daina yin amfani da mutum-mutumi. Masu binciken daga jami'ar Turku (Finland) sun ce "A yanzu, amfanin gaba daya na mutum-mutumi ya wuce girman hadarin kamuwa da cutar sankara," in ji masu bincike daga jami'ar Turku (Finland). "An tabbatar da cewa statins suna rage matsalolin zuciya, don haka wadannan magungunan suna taka muhimmiyar rawa a cikin jiyya."

Koyaya, binciken ya tabbatar da cewa sauran masu sihiri ne ke ɗauke da su ta hanyar da ta dace da masu amfani da Lipitor, Crestor, da kuma Zocor. A cikin wata sanarwa da aka fitar, ya kara da cewa pravastatin na da amfani ga marasa lafiya da ke cikin hadarin kamuwa da ciwon suga. Amfani da fluvastatin (Lescol) yana da alaƙa da raguwar 5% cikin haɗarin haɓakar wannan cutar, da kuma cinyewar lovastatin (Mevacor) tare da 1%. Nazarin da suka gabata sun nuna cewa yin amfani da rosuvastatin (Crestor) yana da alaƙa da haɓakar 27%, yayin da yawan pravastatin yana da alaƙa da kasadar 30% na haɓakar ciwon sukari.

A cikin mutane masu fama da ciwon sukari na 2, matakan sukari na jini suna haɓaka saboda jikinsu baya iya ɗaukar insulin da kyau. A cewar masu binciken, mai yiyuwa ne wasu mutum-mutumi mutum ya lalata rufin insulin ya kuma hana yaduwarsa, wanda a wani bangare yake bayanin binciken.

Shin statins suna amfana fiye da haɗarin haɗari?

Wannan tambaya ba ta da girma a karon farko. Don amsa wannan tambaya, masu binciken sunyi nazarin sakamakon lokacin amfani da statins don rigakafin farko da kuma rigakafin sakandare na cututtukan zuciya. Sakamakon binciken ya ba da shawarar cewa a cikin mahalarta tsofaffi, hadarin ya kasance mafi girma, ba tare da la'akari da yawan sinadarin atorvastatin da simvastatin ba.

Masu binciken sun kammala cewa likitocin yakamata suyi hankali lokacin da suke tsara kwayoyin halitta. Sun ce: "Ya kamata a fi son pravastatin ko, a cikin mawuyacin hali, mura. A cewar su, pravastatin na iya samun fa'ida ga marasa lafiya da ke cikin hatsarin kamuwa da cutar siga.

A cikin wani sharhi game da labarin, masana kimiyya daga Jami'ar Turku (Finland) sun rubuta cewa fa'idodin ginin gaba ɗaya ya wuce haɗarin haɗarin kamuwa da ciwon sukari a cikin ƙananan kashi marasa lafiya. Suna mai da hankali ga gaskiyar cewa an nuna gumaka suna da matukar tasiri wajen hana faruwar jijiyoyin jini, sabili da haka muhimmin bangare ne na ilimin.

Ka tuna cewa wani binciken da masana kimiyya daga Harvard suka yi kwanan nan ya nuna cewa fa'idodin yin amfani da mutum-mutumi na iya zarra hadarin a wasu masu cutar.

Ya kasance game da marasa lafiya masu kiba waɗanda suke da haɗarin CVD da ciwon sukari a lokaci guda.

Dangantaka tsakanin cutar sankarau da cututtukan jijiyoyin jiki

Lalacewa na jijiyoyin cuta cuta ce gama gari. Tare da wata cuta, hadaddun sunadarai-carbohydrate sun sauka a jikin bango, suna tazara da lumen da kuma toshe hanyoyin jini. Wannan ya cutar da jihar da dukkan gabobin jiki da tsarinsu.

Masu ciwon sukari suna da haɗarin haɗarin bugun zuciya da bugun jini. Dalilin haka shine cututtukan hanji da jijiyoyin jini. Marasa lafiya sau da yawa suna fama da rudani da rashin aiki na zuciya saboda lalacewar jijiyoyin zuciya.

A cikin masu ciwon sukari, cututtukan zuciya da jijiyoyin jini suna faruwa sosai da sauri fiye da na mutane kuma ana iya lura dashi yana da shekaru 30.

Amfanin statins a cikin ciwon sukari

Statins na ciwon sukari suna da wannan sakamako:

• rage kumburi, wanda ke kwantar da filayen kwantar da hankali
• haɓaka tafiyar matakai na rayuwa a jiki,
• taimaka wa thinning jini,
• hana rabuwa da ƙwayoyin atherosclerotic, wanda ke nisantar thrombosis,
• rage yawan ƙwayar cholesterol daga abinci,
• haɓaka aikin samar da sinadarin nitric oxide, wanda ke ba da gudummawa ga kwanciyar hankali na jijiyoyin jini da ƙananan yaduwar su.

A ƙarƙashin tasirin waɗannan kwayoyi, yiwuwar kamuwa da cututtukan zuciya masu haɗari, waɗanda ke zama sanadin mutuwar masu ciwon sukari, yana raguwa.

Hadarin ɗaukar mutum-mutumi a cikin ciwon sukari

Ana zaton Statins suna yin tasiri akan metabolism metabolism. Babu wani ra'ayi guda daya game da hanyar yin tasiri kan ci gaban ciwon sukari.

Akwai maganganu na raguwar hankali zuwa insulin a ƙarƙashin rinjayar statins, canji a cikin matakan glucose lokacin amfani dashi akan komai a ciki.

Ga mutane da yawa, maganin statin yana da alaƙa da haɓakar haɗarin kamuwa da cutar sukari da kashi 9%. Amma cikakkiyar haɗarin yana da ƙananan raguwa, tunda a cikin karatun an gano cewa yawan cutar shine yanayin 1 a cikin mutane dubu da aka yiwa jiyya tare da statins.

Abin da statins ne mafi kyau ga ciwon sukari

A cikin hadadden kulawa da masu ciwon sukari, likitoci galibi suna amfani da Rosuvastatin da Atorvastatin. Suna taimakawa rage mummunar cholesterol zuwa matakin da aka yarda da shi. A wannan yanayin, lipids mai ruwa-ruwa yana ƙaruwa da 10%.

Idan aka kwatanta da magungunan ƙarni na farko, al'aura na zamani ana saninsa da babban taro na abubuwan da ke aiki a cikin jini kuma suna da aminci.

Kwayoyin roba ba su da yiwuwar haifar da mummunan sakamako fiye da na halitta, don haka ana umurce su sau da yawa ga masu ciwon sukari. Ba za ku iya zaɓar magani ba da kanku, tunda ana sayar da su duka ta takardar sayan magani. Wasu daga cikinsu suna da contraindications, don haka kawai gwani na iya zaɓar wanda ya dace yana la'akari da halayen mutum na jikin mai haƙuri.

Abin da statins zai taimaka tare da nau'in ciwon sukari na 2

Statins don ciwon sukari na 2 suna da matukar mahimmanci, tunda a wannan yanayin hadarin cutar sankara ya fi yawa. Sabili da haka, an haɗa ƙwayar statin a cikin hadaddun matakan warkewa don cutar. Suna ba da izini na farko da sakandare na ischemia kuma suna haɓaka rayuwar mai haƙuri.

An tsara wa irin waɗannan marasa lafiya magunguna dole ko da a cikin yanayi inda ba su da cututtukan zuciya da ƙwaƙwalwa ko ƙungiyar cholesterol ba ta wuce ka'idodin halattacciyar al'ada ba.

Yawancin bincike sun nuna cewa ga marasa lafiya da ke da nau'in ciwon sukari na biyu, sashi, amma ga marasa lafiya da nau'in farko, ba ya ba da sakamako. Sabili da haka, ana amfani da sashi mafi ƙarancin amfani a cikin far. Lokacin da aka kula da Atorvastatin kowace rana, an yarda da 80 MG, da Rosuvastatin - ba fiye da 40 MG ba.

Statins a cikin nau'in ciwon sukari na 2 na ciwon sukari na taimaka wajan rage rikice-rikice da mace-mace daga cututtukan zuciya na zuciya yayin ci gaba da cututtukan tsarin.

Masana kimiyya yayin gudanar da bincike sun yanke hukuncin cewa hadarin mutuwa yana rage da kashi 25 cikin dari. Mafi kyawun zaɓi don rage ƙwayar cholesterol ana ɗaukar su rosuvastatin. Wannan sabon magani ne, amma alamu na yau da kullun sun isa 55%.

Ya kamata a sani cewa ba shi yiwuwa a faɗi daidai waɗanne statins ne suka fi tasiri, tunda an tsara farji akayi daban-daban, ana la’akari da halayen jiki da abubuwan sinadarai na jini.

Tun da ciwon sukari na mellitus na nau'in na biyu yana da wuyar magani, sakamakon da ake gani daga ɗaukar mutum-mutumi zai bayyana a cikin tsawon har zuwa watanni biyu. Sai kawai tare da taimakon magani na yau da kullun tare da wannan rukuni na magunguna za a iya samun sakamako mai ɗorewa.

Yadda ake ɗaukar statins don ciwon sukari

Hanyar lura da statins na iya zama shekaru. A lokacin jiyya, ya kamata a lura da shawarwari masu zuwa:

1. A bu mai kyau a yi amfani da allunan ne kawai da yamma, tunda a wannan karon akwai aikin cholesterol a cikin hanta.
2. Ba za ku iya tauna allunan ba, an hadiye su duka.
3. Sha ruwa mai tsabta kawai. Ba za ku iya amfani da ruwan innabi ko 'ya'yan itacen da kanta ba, saboda wannan zai shafi tasiri na miyagun ƙwayoyi.

A lokacin jiyya, an haramta shan giya, saboda wannan zai haifar da lalacewa mai guba ga hanta.

Kammalawa

Ko statins na iya haɓaka sukari na jini ko a'a, har yanzu tattaunawa tana gudana. Yawancin bincike sun nuna cewa yin amfani da kwayoyi yana haifar da haifar da cutar a cikin haƙuri guda ɗaya cikin dubu. Musamman irin waɗannan kudade ana buƙatar mutanen da ke fama da ciwon sukari na 2, saboda yana da wahalar magani. Yin amfani da statins a wannan yanayin zai taimaka wajen guje wa ci gaban cututtukan zuciya da rage mace-mace da kashi 25%. Ana iya samun sakamako mai kyau kawai tare da amfani da magunguna na yau da kullun ko tsawanta. Suna shan kwayoyin cuta da daddare, ana wanke su da ruwa, yawanci ana sanya allurai don cimma ci gaba, amma akwai haɗarin halayen da ba a sani ba.

Na farko karshe

“Mun gudanar da gwaje-gwaje a gungun mutane dake cikin hadarin kamuwa da ciwon sukari na 2. Dangane da bayananmu, mutum-mutumi na kara samun damar kamuwa da ciwon sukari da kusan kashi 30%, ”in ji Dr. Jill Crandall, darektan bincike, farfesa a fannin likitanci kuma darektan sashen gwaji na kamuwa da kwaleji a Albert Einstein College of Medicine, New York.

Amma, ta kara da cewa, wannan ba ya nufin cewa kana bukatar ka guji daukar gumakan ne. "Amfanin wadannan magungunan dangane da rigakafin cututtukan zuciya suna da yawa kwarai da gaske kuma an tabbatar da cewa shawarar mu ba ta daina shan su ba, a'a yakamata a bincika wadanda suke shan su a kai a kai domin masu ciwon siga. ".

Wani kwararren masanin cutar kanjamau, Dr. Daniel Donovan, farfesa a fannin likitanci kuma shugaban Cibiyar Nazarin Clinical a Makarantar Magungunan Aikan na Cibiyar Nazarin Cutar Sina, Kiba da Tsarin Kiba a New York, sun yarda da wannan shawarar.

"Har yanzu muna buƙatar rubanya statins tare da babban" mummunan "cholesterol. Amfani da su yana rage hadarin kamuwa da cututtukan zuciya da kashi 40%, kuma cutar sankara na iya faruwa ba tare da su ba, ”in ji Dr. Donovan.

Cikakkun bayanan gwaji

Sabuwar binciken wani bincike ne na bayanai daga wani gwajin cigaba wanda har yanzu yake inda sama da marasa lafiya 3200 daga cibiyoyin cutar siga ta Amurka 27 ke halarta.

Manufar gwajin ita ce hana ci gaban nau'in ciwon sukari na 2 a cikin mutanen da ke da alaƙa da wannan cutar. Dukkan mahalarta taron masu son rai suna da nauyi ko kiba. Duk suna da alamun narkewar sukari mai narkewa, amma ban da cewa an riga an gano su da Cutar 2 na Cutar.

An gayyace su don shiga cikin shirin na shekaru 10 wanda suke auna matakan sukari na jini sau biyu a shekara kuma su kula da yawan abincin da suke ci. A farkon shirin, kusan kashi 4 na mahalarta sun ɗauki mutummutumai, kusa da ƙarshensa game da 30%.

Har ila yau, masana kimiyya sun lura da samar da insulin da kuma jurewar insulin, in ji Dr. Crandall. Insulin wani sinadari ne wanda ke taimakawa jiki juyar da sukari daga abinci zuwa sel a matsayin mai.

Ga waɗanda ke ɗaukar statins, samar da insulin ya ragu. Kuma tare da raguwa a cikin matakinsa a cikin jini, yawan sukari yana ƙaruwa. Binciken, duk da haka, bai bayyana sakamakon statins a kan juriya na insulin ba.

Doctor shawarwarin

Dr. Donovan ya tabbatar da cewa bayanin da aka karba yana da matukar muhimmanci. "Amma ban ce ya kamata mu daina sigoginmu ba. Mai yiyuwa ne cutar zuciya ta wuce ciwon suga, don haka ya zama wajibi a yi kokarin rage hadarin da ke tattare da hakan, ”in ji shi.

"Duk da cewa ba su shiga cikin binciken ba, mutanen da ke dauke da cutar sankarau ta sukari irin 2 yakamata su yi taka tsantsan game da matakan sukari na jini idan sun dauki mutum-mutumi," in ji Dokta Crandall. "Ba a daɗe da bayanai, amma akwai rahotannin lokaci-lokaci cewa sukari yana tashi tare da siffofi."

Likitan ya kuma ba da shawarar cewa wadanda basa cikin hadarin kamuwa da cutar sankarau ba za su iya faruwa da wasu kwayoyin halittu ba. Wadannan abubuwan haɗari sun haɗa da kiba, tsufa, hawan jini, da kuma cutar sankarau a cikin dangi. Abin baƙin ciki, likita ya ce, mutane da yawa bayan shekara 50 suna haɓaka ciwon suga, waɗanda ba su sani ba game da su, kuma sakamakon binciken ya kamata ya sa su yi tunani.