Augmentin ga yara: manufa, abun da ya dace da sashi

Foda don dakatarwar baka, 125 mg / 31.25 mg / 5 ml, 100 ml

5 ml na dakatarwa ya ƙunshi

abubuwa masu aiki: amoxicillin (kamar yadda kwalallen kwayar kwayar kwayar cuta ta amosalatin) 125 mg,

clavulanic acid (a cikin nau'in potassium clavulanate) 31.25 mg,

magabata: xanthan gum, aspartame, succinic acid, silsilar siliki na anhydrous colloidal siliki, hypromellose, dandano busasshen orange 610271 E, busasshen dandano na orange 9/027108, busasshen kayan kwalliyar Rasberi NN07943, busassun molasses dandano bushe 52927 / AR, dioxide silicon dioxide.

Foda yana da fari ko kusan farin tare da kamshin sihiri. Suspensionararren dakatarwar fari fari ne ko kusan fararen fata, lokacin tsayawa, tsabtar farin ko kusan fararen an sannu a hankali suna kafa.

Kayan magunguna

Farmakokinetics

Amoxicillin da clavulanate sun narke sosai cikin mafita mai ruwa tare da pH na jiki, cikin sauri da kuma cikakke daga hancin gastrointestinal bayan maganin baka. Rashin maganin amoxicillin da clavulanic acid shine mafi kyau duka lokacin shan magani a farkon cin abinci. Bayan shan miyagun ƙwayoyi a ciki, asalinsa shine 70%. Bayanan martaba na duka magungunan sun yi kama da sun isa ƙaramin plasma maida hankali (Tmax) a cikin awa 1. Taro na amoxicillin da clavulanic acid a cikin jijiyoyin jini iri daya ne dangane da hadewar amfani da amoxicillin da clavulanic acid, kuma kowane bangare daban.

Ana samun nasarar warkewar amoxicillin da clavulanic acid a cikin gabobin jiki da kasusuwa daban daban, ruwa mai shiga jiki (huhu, gabobin ciki, hanji, adipose, kasusuwa da tsokar jijiyoyin jiki, faranta rai, hanji da jijiyoyin jiki, fata, zazzaɓi, daskarewa, sputum). Amoxicillin da acid na clavulanic a zahiri ba su shiga cikin ruwan cerebrospinal.

Addamar da amoxicillin da clavulanic acid zuwa ƙwayoyin plasma matsakaici ne: 25% na maganin acid na clavulanic da 18% na amoxicillin. Amoxicillin, kamar yawancin penicillins, an keɓe shi a cikin madara. An kuma samo nau'ikan acid na clavulanic acid a cikin madarar nono. Bayan ban da haɗarin hankali, amoxicillin da clavulanic acid basa cutar lafiyar lafiyar jarirai masu shayar da mama. Amoxicillin da acid na clavulanic sun ƙetare shinge na jini.

Amoxicillin ne ke rabuwa da kodan, yayin da clavulanic acid ke keɓaɓɓu daga injunan yara da na yara. Bayan gudanar da magana ta baka na kwamfutar hannu guda ɗaya na 250 mg / 125 mg ko 500 mg / 125 mg, kimanin 60-70% na amoxicillin da 40-65% na clavulanic acid an sake canzawa a cikin fitsari a cikin awanni 6 na farko.

An cire wani abu mai narkewa a cikin fitsari a cikin sinadarin Penicillinic acid wanda yake daidai da kashi 10-25% na adadin da aka ɗauka. Clavulanic acid a jiki yana da cikakken metabolized zuwa 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid da 1-amino-4-hydroxy-butan-2-one kuma an cire shi tare da fitsari da feces, da kuma a cikin nau'in carbon dioxide ta hanyar iska mai ƙuna.

Pharmacodynamics

Augmentin® shine maganin rigakafi wanda ya ƙunshi amoxicillin da clavulanic acid, tare da ɗaukar hoto mai yawa na ƙwayar cuta, mai tsayayya da beta-lactamase.

Amoxicillin shine kwayar kwayar halitta wacce take aiki da kwayar cuta ta giram-gram-gram-gram. An lalata Amoxicillin ta beta-lactamase kuma baya tasiri microorganisms waɗanda suke samar da wannan enzyme. Tsarin aikin amoxicillin shine hana biosynthesis na peptidoglycans na bangon ƙwayar ƙwayar ƙwayar cuta, wanda yawanci yakan haifar da lysis da mutuwar tantanin halitta.

Clavulanic acid shine beta-lactamate, wanda yake kama da tsarin sunadarai zuwa ga penicillins, wanda ke da ikon hana enzymes beta-lactamase na ƙananan ƙwayoyin cuta waɗanda ke tsayayya da penicillins da cephalosporins, don haka hana hanawa na amoxicillin. Beta-lactamases ana samarwa ta hanyar ƙwayoyin cuta masu yawa da aka sa kwayar-gram-gram-gram. Ayyukan beta-lactamases na iya haifar da lalata wasu magungunan ƙwayoyin cuta tun ma kafin su fara cutar da kwayar cuta. Clavulanic acid ya toshe ayyukan enzymes, yana mayar da hankalin mai ƙwayar cuta zuwa amoxicillin. Musamman, yana da babban aiki a kan beta-lactamases na plasmid, wanda ƙarfin jigilar magunguna yana haɗuwa sau da yawa, amma ƙasa da tasiri ga nau'in beta-lactamases na chromosomal 1.

Kasancewar acid na clavulanic acid a cikin Augmentin® yana kare amoxicillin daga tasirin beta-lactamases kuma yana haɓaka ɗaukar hoto na ayyukan ƙwayoyin cuta tare da haɗuwa da ƙwayoyin cuta waɗanda galibi suna jure sauran penicillins da cephalosporins. Clavulanic acid a cikin nau'in magani guda ba shi da tasirin ƙwarin ƙwayar cuta a asibiti.

Tsarin ci gaba na juriya

Akwai hanyoyi guda 2 don haɓaka juriya ga Augmentin®

- rashin aiki ta hanyar beta-lactamases na kwayan cuta, wadanda basu da hankali ga tasirin clavulanic acid, gami da azuzuwan B, C, D

- lalata gurɓataccen furotin na penicillin, wanda ke haifar da raguwa da kusancin ƙwayoyin cuta dangane da ƙwayoyin cuta

Rashin ingancin bango na ƙwayar cuta, da kuma abubuwan tsintsin, na iya haifar ko taimakawa ga ci gaban juriya, musamman ma a cikin ƙwayoyin cuta mara kyau.

Augmentin®yana da sakamako mai kashe kwayoyin cuta akan wadannan kwayoyin:

Gram-tabbatacce aerobes: Encerococcus faecalis,Gardnerella vaginalis,Amintakarwa (m ga methicillin), coagulase-korau staphylococci (kula da methicillin), Alawarfafawar ƙwaƙwalwa,Kwayar cutar huda ciki1,Pyogenes mai ƙarfi da sauran beta hemolytic streptococci, rukuni Budurwai budurwa,Bacillius anthracis, Listeria monocytogenes, astroroides na Nocardia

Gram-korau jirgin sama: Actinobacillussabbinna,Kabarinspp.,Eikenellacorrodens,Haemophilusmura,Moraxellacatarrhalis,Neisseriagonorrhoeae,Pasteurellamultocida

anarobic microorganisms: Bacteroides fragilis,Fusobacterium nucleatum,Prevotella spp.

Orarin ƙananan ƙwayoyin cuta tare da yiwuwar juriya

Gram-tabbatacce aerobes: Enterococcusfitsari*

Microorganisms tare da juriya ta halitta:

gram koraujirgin sama:Acinetobacternau'in,Citrobacterfreundii,Enterobacternau'in,Legionella pneumophila, Morganella morganii, Providencianau'in, Pseudomonasnau'in, Serratianau'in, Stenotrophomonas maltophilia,

wani:Kalamunda trachomatis,Chlamydophila ciwon huhu, Chlamydophila psittaci, Coxiella burnetti, Mycoplasma ciwon huhu.

*Halin dabi'a na dabi'a yayin rashin juriya

1 Ban da damuwa Kwayar cutar huda cikimaganin penicillin

Alamu don amfani

- m kwayan sinusitis

- m otitis kafofin watsa labarai

- infectionswaƙwalwar ƙwayar ƙwayar ƙwayar cuta na ciki (ƙari na kullum

mashako, ciwon huhu na huhu, huhun ciwan kansa, tarin al'umma

- cututtukan cututtukan mahaifa, ciwan ciki

- cututtukan fata da fata masu taushi (musamman, cellulite, kwari

dabbobi, m rashin kuzari da phlegmon na maxillofacial

- cututtuka na kasusuwa da gidajen abinci (musamman, osteomyelitis)

Sashi da gudanarwa

Dakatarwar da aka yi don gudanar da maganin baka an yi amfani dashi ne a cikin ilimin likitanci.

Abun hankali ga Augmentin® na iya bambanta ta hanyar yanki da lokaci. Kafin rubuta magani, idan zai yiwu ya zama dole don tantance hankalin jijiyoyin jikinsu daidai da bayanan gida da tantance hankalin ta hanyar samin samfuri da kuma nazarin samfurori daga wani haƙuri, musamman idan akwai masu kamuwa da cuta.

An saita tsarin sashi daban-daban gwargwadon shekaru, nauyin jiki, aikin koda, masu kamuwa da cuta, da kuma tsananin kamuwa da cuta.

Ana bada shawarar Augmentin® a farkon cin abinci. Tsawon lokacin jiyya ya dogara da amsawar mai haƙuri ga magani. Wasu cututtukan cuta (musamman, osteomyelitis) na iya buƙatar hanya mai tsayi. Kada a ci gaba da jiyya na fiye da kwanaki 14 ba tare da sake nazarin yanayin mai haƙuri ba. Idan ya cancanta, yana yiwuwa a aiwatar da matakin motsa jiki (na farko, cikin jiyya na miyagun ƙwayoyi tare da mika mulki ga na baka).

Yara daga haihuwa zuwa shekara 12 ko yin nauyin ƙasa da kilo 40

Girman, dangane da shekaru da nauyi, ana nunawa a cikin nauyin mg / kg na jiki a rana, ko a cikin milliliters na dakatarwar da aka gama.

Sanarwa da aka ba da shawarar

Daga 20 mg / 5 mg / kg / rana zuwa 60 mg / 15 mg / kg / day, ya kasu kashi uku. Don haka, ana amfani da jigilar magunguna 20 mg / 5 mg / kg / day - ana amfani da 40 mg / 10 mg / kg / day don kamuwa da cuta mai saurin kamuwa da cuta (tonsillitis, cututtukan fata da kyallen takarda mai taushi), ƙwayoyin magunguna masu yawa (60 mg / 15 mg / kg / rana) an wajabta su idan akwai mummunan cututtuka - otitis media, sinusitis, ƙananan ƙwayar cuta na ciki da kamuwa da cuta na urinary fili.

Babu bayanan asibiti game da amfani da Augmentin®

125 mg / 31.25 mg / 5 ml akan 40 mg / 10 mg / kg / rana a cikin yara 'yan shekaru 2 da haihuwa.

Augmentin® tebur zaɓi na tebur zaɓi dangane da nauyin jikin mutum

Abun da magani

Augmentin ya ƙunshi manyan abubuwan biyu waɗanda ke ƙayyade fa'idodin amfani da maganin. Wadannan sun hada da:

• Amoxicillin kwayoyi ne na kwayoyi masu amfani da kwayoyin kara kuzari. Yana lalata microorganism daban-daban, na gram-tabbatacce kuma gram-korau. Duk da ingancin kaddarorin, kayan yana da matukar koma baya. Amoxicillin yana kula da beta-lactamases. Ma'ana, hakan bai shafi waɗannan ƙananan ƙwayoyin halittar da suke samar da wannan enzyme ba.
• Clavulanic acid - da nufin haɓaka bakan aikin aikin rigakafi. Wannan abu yana da alaƙa da maganin rigakafin penicillin. Inhibitor na beta-lactamase ne, wanda ke taimakawa kare amoxicillin daga hallaka.

Menene sashi na magani

Augmentin ya ƙunshi abubuwa biyu. An nuna lambar su akan allunan ko dakatarwa. Idan ya zo game da foda don dakatarwa, abin lura kamar haka:

• Augmentin 400 - ya ƙunshi 400 mg na amoxicillin da 57 MG na clavulanic acid a cikin 5 ml na ƙwayoyin cuta,
• Augmentin 200 - ya ƙunshi 200 mg na amoxicillin da kuma 28.5 mg na acid,
• Augmentin 125 - a cikin milliliters 5 na miyagun ƙwayoyi ya ƙunshi 125 mg na amoxicillin da 31.25 mg na clavulanic acid.

Allunan zasu iya samun 500 MG da 100 MG na amoxicillin da 100 ko 200 MG na clavulanic acid, bi da bi.

Ta wace hanya ce ake kwantar da kwayoyin?

Akwai nau'ikan magungunan da yawa. Wannan maganin rigakafi iri ɗaya ne, amma ya bambanta da yadda ake amfani da abu mai aiki da nau'in sakin (Allunan, dakatarwa ko foda don shirye-shiryen injections).

1. Augmentin - yana samuwa a cikin nau'ikan allunan don maganin magana, dakatarwa ga yara da foda don ƙirƙirar allura,
2. Augmentin EC foda ne don dakatarwa. An tsara shi musamman ga yara 'yan ƙasa da shekara 12 ko manya waɗanda saboda dalilai daban-daban basa iya hadiye allunan,
3. Augmentin SR kwamfutar hannu ce don gudanar da maganin baka. Suna da sakamako mai daɗewa kuma an sake surar mai aiki mai aiki.

Yadda ake shirya dakatarwa

An shirya Augmentin a cikin tsari fitarwa kai tsaye kafin amfani na farko. A cikin tsari mai narkewa, an adana shi a cikin firiji don ba a wuce kwanaki 7 ba. A tsawon wannan lokacin, ba za a iya amfani da miyagun ƙwayoyi ba.

Shirye-shiryen "Augmentin 400" ko dakatarwa 200 ana aiwatar da su ne bisa ga wannan tsarin:

1. Bude kwalbar sai a zuba a cikin 40 milliliters na ruwan zãfi, sanyaya zuwa zafin jiki na ɗakin.
2. Shayar da vial da kyau har sai an narkar da foda gaba ɗaya. Ka bar mintuna biyar.
3. Bayan wannan lokacin, zuba ruwa mai tafasa har zuwa alamar da aka nuna akan kwalban. Shake magani a sake.
4. Jimlar 64 milliliters na dakatarwa yakamata a samu.

An shirya dakatarwar Augmentin 125 ta wata hanya dabam. A cikin kwalba, kuna buƙatar zuba 60 milliliters na ruwan zãfi a zazzabi a ɗakin. Shake da kyau kuma bar shi daga minti biyar. Bayan haka kuna buƙatar ƙara ƙarin ruwa, zuba shi a kan alamar, wanda aka nuna akan kwalban. Shake abubuwan da ke ciki da kyau kuma. Sakamakon shine 92 milliliters na kwayoyin rigakafi.

Ana iya auna adadin ruwa da igiyar muni. An haɗe shi da kwalbar, yana cikin kunshin tare da umarnin da jirgin ruwa tare da kwayoyin. Nan da nan bayan shiri, dole ne a sanyaya kwayoyin. Ya kamata a adana shi a zazzabi ba ƙasa da digiri 12 ba.

Hankali! Ba za a iya fitar da foda daga murfin cikin wani jirgin ruwa ba. Wannan zai haifar da gaskiyar cewa maganin rigakafi ba zai sami tasiri ba.

Umarnin don amfani

An auna dakatarwar da aka gama ta amfani da sirinji ko kofin aunawa, wanda yazo tare da kit ɗin. Ana sanya maganin a cikin cokali guda, amma zaka iya sha tare da gilashin. Bayan an ɗauka sai a shafa a ƙarƙashin ramin tsarkakakken ruwan dumi. Idan yana da wahala ga yaro ya ɗauki dakatarwa a cikin tsarkakakken sa, to ana iya narkar da shi cikin ruwa a cikin rabo na 1 zuwa 1. Amma da farko, yakamata a shirya adadin maganin rigakafi. Ana fi ɗaukar Augmentin kai tsaye kafin abinci. Wannan zai rage tasirin mummunar sakamako na miyagun ƙwayoyi akan ƙwayar gastrointestinal.

Ana yin lissafin magungunan gwargwadon shekarun, nauyin yaro da yawan abu mai aiki.

Augmentin 125 mg

• Yara 'yan kasa da shekaru 2 zuwa 5 na shan kilo 1.5 zuwa 2.5 na Augmentin sau 3 a rana,
• Yara daga shekara 1 zuwa shekara 5, masu nauyin kilo 5 zuwa 9, suna shan ml 5 sau uku a rana,
• Yara daga shekara 1 zuwa shekara 5, tare da nauyin kilo 10 zuwa 18, ya kamata su sha 10 ml na kwayoyin sau uku a rana,
• Yaran da suka manyanta, daga shekaru 6 zuwa 9, matsakaita nauyi daga kilo 19 zuwa 28, suna daukar 15 ml sau 3 a rana,
• Yara daga shekaru 10 zuwa 12 masu nauyin 29 - 39 kilo suna sha 20 milliliters na rigakafi sau uku a rana.

Augmentin 400

• Yarinya daga shekara 1 zuwa shekaru 5 ana bada shawara don shan 5 ml na miyagun ƙwayoyi sau biyu a rana. Matsakaicin nauyin kilo 10 zuwa 18,
• Yara daga shekaru 6 zuwa 9 ya kamata su ɗauki 7.5 milliliters sau biyu a rana. Yawan nauyin yara ya kamata ya fadi cikin kilo 19 zuwa 28,
• Yara daga shekaru 10 zuwa 12 ya kamata suyi amfani da mililirs 10 sau biyu a rana. Matsakaicin matsakaici daga kilo 29 zuwa 39.

Hankali! Daidaitaccen maganin yana daidaita da likitan halartar. Ya dogara da digiri da tsananin cutar, contraindications da sauran nuances.

Idan jariri bai wuce wata uku da haihuwa ba

A cikin jariran da ba suyi watanni 3 ba tukuna, har yanzu ba a kafa aikin koda ba. Rarrabar miyagun ƙwayoyi zuwa nauyin jiki yana likitan likita. An ba da shawarar shan 30 MG na magani a cikin kilo 1 na nauyin jariri. Sakamakon da ya haifar ya kasu kashi biyu kuma ana baiwa yaro magani sau biyu a rana, kowane awa goma sha biyu.

A matsakaici, ya juya cewa jariri mai nauyin kilo 6 an wajabta shi na milliyan 3.6 na dakatarwa sau biyu a rana.

Allunan magani Augmentin

An wajabta maganin rigakafi a cikin allunan don yara marasa shekaru 12, waɗanda nauyin jikinsu ya wuce kilo 40.

Don cututtuka masu laushi da matsakaici, ɗauki 1 kwamfutar hannu na 250 + 125 MG sau uku a rana. Yakamata a bugu dasu duka awanni 8.

Don kamuwa da cuta mai tsanani, ɗauki 1 kwamfutar hannu 500 + 125 MG kowane 8 hours ko 1 kwamfutar hannu 875 + 125 MG kowane 12 hours.

Lokacin da aka yi amfani da dakatarwa

Karamin hanya ga yara shine kwanaki 5, matsakaicin shine na kwanaki 14. Amma a kowane yanayi, amfani da maganin rigakafi ya kamata ya kula da likitan da ke halartar. An bada shawarar Augmentin don amfani dashi a cikin halayen masu zuwa:

• Idan an gano cututtukan cututtukan tsokoki na sama da gabobin ENT (kunnuwa, makogwaro ko hanci),
• Tare da halayen kumburi a cikin ƙananan na numfashi (bronchi ko huhu),
• Ana ba da shawarar Augmentin don amfani yayin kamuwa da cuta na tsarin ƙwayar cuta. A wannan yanayin, yawancin lokuta muna magana ne game da manya ko manyan yara. Yawancin lokaci, ana amfani da maganin rigakafi don cystitis, urethritis, vaginitis, da dai sauransu.
• Tare da cututtukan fata na fata (boils, abscesses, phlegmon) da kumburi ƙasusuwa tare da gidajen abinci (osteomyelitis),
• Idan an gano marasa lafiya da cututtukan cututtukan cututtukan iri ɗaya (cututtukan cututtukan ƙwayar cuta ko ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta).
• Tare da nau'ikan cututtukan da aka haɗe - cholecystitis, cututtukan cututtukan baya.

Hankali! An wajabta amfani da kwayar rigakafi ta hanyar injections yayin aikin bayan aikin.

Menene contraindications da sakamako masu illa?

Magungunan suna da iyakoki da yawa a cikin amfani da sakamako masu illa. Ba za a iya amfani da shi a waɗannan halayen masu zuwa ba:

1. Idan marasa lafiya sunada rashin lafiyar amoxicillin ko acid na clavulanic. Idan an lura da rashin lafiyan halayen ƙwayoyin cuta irin na penicillin, to bai kamata a yi amfani da Augmentin ba.
2. Idan yayin cincin amoxicillin na baya, an yi rikodin maganganun hanta ko aikin koda.
3. Mutanen da ke fama da koda ko gazawar hanta, yara akan hawan jini yakamata su kusanci amfani da maganin. Sashi a cikin irin wannan yanayi ne wajabta ta kawai likita halartar.

Abubuwan da ke haifar da sakamako masu illa na iya haɗawa da aiki da narkewa a cikin narkewa (ana iya bayyana shi ta amai, tashin zuciya, zawo, zafin ciki). Bayyanannun bayyanannun candidiasis, ciwon kai, farin ciki. Wani lokacin jariri ya zama mai juyayi, yana damuwa da rashin bacci da kuma tashin hankali. Daga fata - rashes, amya, itching mai zafi da ƙonawa.

Bayani mai amfani

1. Yakamata a dakatar da dakatarwar Augmentin. Abubuwan da ke cikin laka suna daidaitawa zuwa kasan, saboda haka dole ne kwalban maganin ya girgiza kafin kowane kashi. Ana auna magungunan tare da kofin aunawa ko sirinji na yau da kullun. Bayan an yi amfani da su, dole ne a wanke su a ƙarƙashin rafin ruwan dumi.
2. Ana sayar da kowane irin maganin rigakafi a cikin magunguna; Hakanan za'a iya ba da umarnin a kantin magani na kan layi.
3. Matsakaicin farashin dakatarwa ya dogara da yankin da kuma farashin farashin kantin magani. Yawancin lokaci yana farawa daga 225 rubles.
4. Shan maganin rigakafi ana bada shawarar kawai akan shawarar likita. Magungunan Antibacterial sune magunguna masu mahimmanci, shan ba tare da takardar sayan magani ba na iya haifar da sakamako mara kyau.
5. Kamar kowane magani, Augmentin yana da analogues. Waɗannan su ne Solyutab, Amoksiklav da Ekoklav.
6. Kwayar rigakafi tana haifar da dysbiosis na hanji, don haka kuna buƙatar shan probiotics yayin ɗaukar magani, ko kuma ku ɗauki hanyar probiotics bayan an gama magani.

Kammalawa

Augmentin ga yara shine haɗakar ƙwayoyin cuta na janar na aikin. Yana taimakawa tare da cututtuka daban-daban, duka biyun na numfashi da sauran tsarin jikin mutum. Maganin Augmentin ya dogara da shekarun yaro, nauyinsa, tsananin cutar, contraindications da sauran fannoni. Yayin shan kwayoyin, ya zama dole ya kasance karkashin kulawar likitan halartar.

Ka tuna cewa likita ne kawai zai iya yin maganin ƙwayar cuta, ba magani na kai ba tare da shawarwari da yin gwajin likita ta ƙwararren likita ba. Kasance cikin koshin lafiya!