Yaya ake amfani da Fenofibrate?

Fenofibrate magani ne na rage rage kiba wanda ake amfani dashi don magance hypercholesterolemia da hadewar hyperlipidemia. Abubuwan da suka shafi sun dogara da kunnawa masu karɓar PPARα. Yawancin lokaci ana amfani da maganin sau ɗaya a rana tare da abinci. Yawancin sakamako masu illa na yau da kullun sune ciwon kai da ciki. Fenofibrate na iya sa fatar jiki ta kula da hasken rana.

Abun ciki da nau'i na saki

Fenofibrate yana samuwa a cikin nau'in farin lu'ulu'u mai fure, wanda kusan a cikin ruwa ruwa yake. Ana samar da prodrug a cikin jiki don aiki fenofibric acid mai aiki.

A halin yanzu (2018), ana amfani da fnofibrate micronized mafi yawa.

Ban sha'awa! Kamfanin samar da magunguna ya samar da kamfanin sarrafa magunguna na Fournier Pharma. A cikin Amurka, ya zama magani mafi saurin wadatar da lipid a kasuwa.

Kayan magunguna

PPARs masu karɓar nukiliya ne waɗanda ke aiki ta hanyar ligands na halitta ko na roba, kuma suna haɓaka ko hana faɗar wasu kwayoyin. Akwai PPA alpha, beta da gamma masu karɓa. Kusan dukkanin fibrates suna ɗaure musamman don masu karɓa na alpha.

Babban sakamakon maganin:

• Yana hana bayyanar apolipoprotein C3 (APOC3), wanda a cikin hakan yana hana lipoprotein lipase da alhakin hydrolysis na intravascular triglycerides (TG). PPAR-alpha yana ƙara yawan ayyukan lipoprotein lipase, wanda ke rage taro na triglycerides a cikin jini
• Yana haɓaka aikin APOA1, APOA2 sabili da haka HDL
• A lokacin gwaji na asibiti da aka gudanar tare da fenofibrate, jimlar cholesterol ta ragu tsakanin 20 da 25%, kuma HDL ya karu daga 10 zuwa 30%
• Rage magana daga endothelin-1, wanda yake mai ƙarfi vasoconstrictor. Hakanan, tare da wannan inji, fibrates suna rage bayyanar cytokines, musamman IL-1 da IL-6, sabili da haka, suna da tasirin anti-mai kumburi. Hakanan an san cewa yin amfani da PPAR-alpha, wasu fibrates zasu iya rage magana da fibrinogen, saboda haka suna iya samun tasirin antithrombotic
• Yana ƙara ɓoyewar ƙwayar cholesterol ta bile, wanda zai iya ba da gudummawa ga lithogenesis.

Matsakaicin aikin plasma maida hankali (Cmax) an cimma shi awanni 2-4 bayan gudanarwar baka. Bioavailability yana raguwa sosai idan an dauki maganin tare da abinci. Bayan gudanar da maganin baka, fenofibrate yana saurin haɓaka ta esterases zuwa cikin metabolite mai aiki - fenofibric acid. Fenofibric acid yana da alaƙa da plasma albumin (fiye da 98%). Ba a sami fenofibrate mai canzawa ba a cikin plasma. Maganin ba magani bane na cytochrome P450. Magungunan ba ya shiga cikin ƙwayar cuta ta hepatic microsomal.

Ana cire miyagun ƙwayoyi daga jiki musamman tare da fitsari. Kusan duka samfurin an shafe shi a cikin mako guda. Ana cire Fenofibrate gaba ɗaya a cikin nau'i na fenofibric acid da asalinsa na glucuroconjugate. A cikin marasa lafiya tsofaffi, share fenofibric acid baya canzawa. Nazarin Pharmacokinetic bayan kashi ɗaya da ci gaba da magani yana nuna ƙarancin tarawa. Fenofibric acid ba a kawar da shi ta hanyoyin dialysis. Rabin-rabi shine kimanin awanni 20.

Alamu don amfani

Matsakaicin farashin Fenofibrate shine 800 Rasha rubles.

Ana amfani da Fenofibrate ban da abinci ko wasu marasa magunguna (kamar motsa jiki, asarar nauyi) a cikin jiyya na nau'in II, III, IV da V hyperlipidemia. Fenofibrate yakamata a yi la'akari dashi azaman magani na biyu. Za'a iya amfani da maganin ne kawai lokacin da yawan yin narkarda ƙwayar lipids a cikin jini. Hakanan za'a iya amfani dashi azaman madadin idan wasu abubuwa masu aiki daga ƙungiyar Statin ba suyi aiki ba ko suna ba da izini.

A cikin binciken, fenofibrate magani ya rage yawan bugun zuciya a cikin cututtukan zuciya. Koyaya, ba a kafa cewa likitan yana da tasiri mai kyau ga ci gaban cututtukan zuciya ba.

Umarnin don amfani

Dangane da umarnin, ana ɗaukar fenofibrate sau ɗaya a rana. Abincin abinci na lokaci guda dan kadan rage bioavailability na miyagun ƙwayoyi. An bada shawara a sha kwamfutar hannu da aka ɗauka tare da ruwa.

Amfani da lokacin daukar ciki da shayarwa ba shi da shawarar, saboda, bisa ga umarnin don amfani, miyagun ƙwayoyi suna da tasirin teratogenic.

Contraindications, sakamako masu illa, yawan wuce gona da iri, hulɗa da miyagun ƙwayoyi

Fenofibrate an contraindicated idan akwai wani hypersensitivity, nephropathy, hanta gazawar, m hepatic tabarbarewa, cututtuka na gallbladder, baya photoallergic ko dauki hoto. Game da fatawar fata (daukar hoto) tare da jan launi, sanya fata, amai da itching, ya kamata a daina sashi mai aiki.

An ba da shawarar cewa nan da nan ku sanar da likitanka jin zafi, rauni, da rauni na jijiyoyin jiki. Mata masu yiwuwar haihuwar yakamata su mai da hankali ga ingantaccen maganin hana haihuwa yayin jiyya.

Fenofibrate yana haifar da rikicewar ciki da na ciki, yana kara enzymes hanta, taro na homocysteine. Hakanan yana haifar da ciwon tsoka, raunin jiki, gallstones, da kuma tayar da matakan kinine. Nazarin asibiti ya bayyana cewa miyagun ƙwayoyi na iya haifar da babbar damuwa ta rashin damuwa tare da amfani na dogon lokaci.

Abun hulɗa na miyagun ƙwayoyi yana yiwuwa tare da maganin anticoagulants na baki, cyclosporine, abubuwan hepatotoxic da monoamine oxidase blockers. Fenofibrate shine mai hana wasu cytochrome P450 isoforms.

Babban analogues na Fenofibrate: Fenofibrate Canon da Tricor.

Canjin Fenofibrat

Manufacturer - Canonfarm Production CJSC (Tarayyar Rasha)

Farashi - daga 820 rubles

Bayanin - allunan da aka rufe fim da ake amfani da su don maganin cututtukan jini masu hawan jini

Ribobi - yana rage maida hankali kan ƙananan ƙwayoyin lipoproteins da yawa, yana ƙaruwa HDL kuma yana da tasirin antithrombotic a cikin allurai na warkewa

Cons - yana haifar da gajiya, ciwon kai, kasala, ciwon ciki, hepatitis da kuma rashin lafiyar koda

Manufacturer - Nauyin kayan abinci (Faransa)

Farashi - daga 1200 rubles

Bayanin - Allunan da aka sanya fim dauke da fenofibrate na micronized, wanda ake amfani da shi don kula da babban adadin cholesterol da triglycerides a cikin jini

Ribobi - yana rage taro LDL, VLDL, fibrinogen kuma yana ƙara HDL. Abubuwan da ke cikin alamun alamun kumburi da uric acid a cikin jini shima yana raguwa.

Cons - yana haifar da dyspepsia, haɓakar enzymes hanta, jaundice, gallstones, rhabdomyolysis, erectile dysfunction and tsananin cephalgia

Saki siffofin da abun da ke ciki

Magungunan an yi su ne da nau'ikan allunan da aka sanya wa membrane. Kowane rukuni na miyagun ƙwayoyi ya ƙunshi 145, 160 ko 180 MG na micronozed fenofibrate a cikin nau'i na nanoparticles. Kamar yadda ake amfani da ƙarin kayan aikin:

• madara sukari
• microcrystalline cellulose,
• Sankarinka
• sabbinne,
• silsilal daskide siliki
• yi nasara
• suryum sulfate da scusum sodium,
• magnesium stearate.

Magungunan an yi su ne da nau'ikan allunan da aka sanya wa membrane.

Harsashi na waje ya ƙunshi talc, gumant xanthan, titanium dioxide, polyvinyl giya da soyac soin. Allunan fararen suna da siffar elongated tare da zane a gefuna biyu na nau'in sashi, yana nuna harafin farko na abu mai aiki da sashi.

Hanyar aikin

Allunan magani na Fenofibrate suna cikin rukunin wakilai na hypoglycemic kuma sune asalin acid na fibroic acid. Wannan abu yana da ikon shafar matakin lipids a jiki.

Abubuwan da ke cikin magunguna suna faruwa ne saboda kunnawar RAPP-alpha (mai karɓar mai karɓar mai sauron peroxisis). Sakamakon sakamako mai ban sha'awa, ana haɓaka tsarin haɓaka kitse mai narkewa da haɓakar ƙananan lilaprosins mai ƙarancin jini (LDL). Samuwar apoproteins AI da AH suna haɓaka, saboda wannan shine ƙara girman lipoproteins mai yawa (HDL) yana ƙaruwa 10-30% kuma an kunna lipoprotein lipase.

Sakamakon maidowa da mai mai yawa yayin da ya faru da rikice-rikice na samuwar VLDL, fili fenofibrate yana haɓaka fitowar LDL, yana rage adadin ɗimbin daskararre na rashin ƙarfi mai yawa da ƙananan girma.

Ana karuwa da matakan LDL a cikin marasa lafiya a cikin haɗarin haɓakar cutar cututtukan zuciya.

Magungunan yana taimakawa rage cholesterol ta 20-25% kuma triglycerides da 40-55%. A gaban hypercholesterolemia, matakin cholesterol da ke hade da LDL yana raguwa zuwa 35%, yayin da hyperuricemia da atherosclerosis suna raguwa a cikin tattarawar uric acid a cikin jini ta 25%.

Pharmacokinetics

Lokacin da aka yi magana da baki, ƙwayar ƙaramin abu mai fenofibrate yana haɗuwa da kusancin ɓangaren ƙaramin hanji ta amfani da microvilli, daga inda aka tsoma shi cikin tasoshin jini. Lokacin da ya shiga cikin hanji, abu mai aiki nan da nan ya yanke jiki zuwa fenofibroic acid ta hanyar hydrolysis tare da esterases. Kayan lalata ya isa mafi girman matakan plasma a cikin awanni 2-4. Cin abinci a kan yawan sha da bioavailability ba ya shafar saboda abubuwan nanoparticles.

Lokacin da ya shiga cikin hanji, abu mai aiki nan da nan ya yanke jiki zuwa fenofibroic acid ta hanyar hydrolysis tare da esterases.

A cikin jini, aiki mai aiki yana ɗaure wa alkumin plasma albashi da kashi 99%. Magungunan ba ya shiga cikin metabolism metabolism. Rabin rayuwar ya kai awowi 20. A yayin gwaji na asibiti, babu wasu lokuta na tarawa duka tare da guda ɗaya ko tare da gudanar da maganin na dogon lokaci. Hemodialysis ba shi da tasiri. Magungunan an cire su ta hanyar fenofibroic acid gaba daya a cikin kwanaki 6 ta hanyar tsarin urinary.

Contraindications

Ba a sanya magani ba saboda tsananin contraindications:

• hypersensitivity to fenofibrate da sauran tsarin abubuwa na miyagun ƙwayoyi,
• cutar hanta
• mai rauni daskararction,
• cututtukan galactosemia da fructosemia, rashi na lactase da sucrose, glucose da kuma haɗarin galactose,
• tarihin cututtukan tsoka na gado,
• ji na haske zuwa haske lokacin da aka kula da Ketoprofen ko wasu fibrates,
• pathological tsari a cikin gallbladder.

Ba a sanya magani ba don maganin galactosemia.
Ba a sanya magani ba don cutar hanta.
Ba a sanya magunguna don maganin cututtukan ƙwayoyi na gado ba.
Ba'a wajabta magunguna don lalata daskararction koda.
Ba a sanya magani ba don cututtukan tsoka na gado.
Ba a sanya magani ba don maganin cututtukan ƙwayar cuta a cikin ƙwayar cuta.

Mutanen da ke da alaƙa da gyada da gyada ba su sha maganin ba.

Medicungiyar magani, INN, ikon yinsa

Fenofibrate yana cikin rukunin musamman - magunguna masu rage ƙwayar lipid waɗanda aka yi akan tushen fibroic acid. Irin waɗannan kwayoyi suna da ikon rage haɗarin cholesterol "mara kyau" a cikin jini da rage matakin triglycerides.

Ana amfani da miyagun ƙwayoyi don rage taro na lipids, tarawa wanda ya wuce wanda ya cutar lafiyar mutane. Sau da yawa ana wajabta shi ga marasa lafiya da ciwon sukari mellitus, tare da cututtukan zuciya da jijiyoyin jini (alal misali, ischemia cardiac, atherosclerosis) don daidaita matakan lipids.

INN shine Fenofibrate, tunda wannan shine bangare wanda yake kunshe a cikin magunguna kuma yana tantance hanyar aikinta akan jiki.

Fitar saki, farashi a Rasha

Magungunan an saki su ne a cikin nau'ikan allunan da suke da fararen launi, da zagaye mai zagaye da tsinkaye. Kowane kwamfutar hannu ta ƙunshi milimita 145 na kayan aiki masu aiki. An cakuɗe su cikin roba mai filastik don guda 7, 10 ko 15. Gaba ɗaya, a cikin akwatin kwali akwai allunan 10 zuwa 100.

Farashin ya dogara da adadin allunan a cikin kunshin, kazalika da wurin siyan magungunan. Matsakaicin farashin don fakitin 30 Allunan 145 na 145 a cikin kantin magunguna na manyan biranen Rasha an gabatar dasu a cikin tebur.

Yawancin farashi mai araha sune ke ba da magunguna ta kan layi. A can za ku iya yin oda isar da sauri kai tsaye zuwa gidan ku.

Abun hadewa

Babban aikin kayan maganin shine fenofibrate. Ana kiranta azaman fibroic acid (fibrates). Tabletaya daga cikin kwamfutar hannu guda ɗaya ya ƙunshi kashi 145 na wannan abun. Bugu da ƙari, abun da ke cikin miyagun ƙwayoyi ya haɗa da irin waɗannan abubuwan haɗin - cellulose, steneste magnesium, povidone, mannitol, sitaci, silicon dioxide. Suna da aikin taimako.

Kayan Aikin Magunguna

Fenofibrate yana iya kunna takamaiman karɓar alpha (RAPP). Wannan yana haifar da ƙara yawan lipolysis da kuma kawar da haɗarin lipoproteins mai haɗari daga jini, wanda zai iya tarawa kuma a ajiye shi a bangon jijiyoyin jini, yana haifar da mummunan sakamako. A wannan yanayin, ana lura da sakamako masu zuwa:

• raguwa a cikin triglycerides da mummunan cholesterol,
• rage a cikin adadin uric acid (sakamako uricosuric),

normalization na tariletletation (rigakafin thrombosis),

Bayan gudanar da baki, an magance ƙwayar maganin a cikin ƙwayar gastrointestinal bayan sa'o'i 4. Idan an tsari shi da kyau, to maida hankali a cikin jinin abu mai aiki ya zama tsayayye. Fenofibrate ya ɗauka kusan gaba ɗaya ga garkuwar jini.

A cikin aiwatar da sarrafa fenofibroic acid an kafa. Ba ya shiga cikin metabolism metabolism. Nishadi yana faruwa ta hanjin kodan. Rabin rayuwa ana lura da sa'o'i 20 bayan gudanarwa. Zai ɗauki kimanin kwanaki 6 don kawar da samfurori na fenoforbit metabolites gaba ɗaya.

Alamu da iyakancewa

An tsara maganin don rage matakin triglycerides da ƙarancin ƙarancin cholesterol tare da irin waɗannan cututtukan:

Ciki mai hadewar diski. Yana yawan tasowa tare da irin waɗannan cututtuka:

• ciwon sukari mellitus
• ischemia
• matakan atherosclerotic a cikin yanki ko aksar carotid,
• na ciki artery sabobin,
• sauran rikitarwa na jijiyoyin jini. Ana amfani da miyagun ƙwayoyi sau da yawa a hade tare da statins don rage triglycerides da haɓaka HDL (cholesterol mai amfani).

Dogon likita da likitan mata ne ke tantance tsawon lokacin da kulawa. Kafin rubuta magani, ya kamata ka tabbata cewa mara lafiyar ba shi da irin wannan maganin:

• mutum ɗan haƙuri zuwa ga abubuwan da suke hada magunguna,
• mai rauni na koda
• tashin hankali ga fibrates da Ketoprofen,
• maganin ciwon sikila,
• na kullum ko m pancreatitis (wanin wannan wanda ya haifar da hauhawar jini),
• yara da matasa,
• tsawon GW,
• ciki
• aikin hanta mai rauni (cirrhosis).

Ba a gwada maganin ba akan yara kanana, mata masu juna biyu, da uwaye masu shayarwa. Don haka, ba a san yiwuwar haɗarin irin waɗannan alƙawura ba. Tunda fenofibrate zai iya shiga cikin cikin mahaifa kuma zuwa cikin madara, ba da shawarar amfani da shi don kar ya cutar da jariri ba.

Tare da tsananin taka tsantsan kuma a karkashin kulawar likita, ana amfani da miyagun ƙwayoyi don maganin hypothyroidism, cututtukan koda, da kuma kulawa da tsofaffi marasa lafiya da mutanen da ke shan barasa.

Koyarwa don amfani

Yana da mahimmanci a ɗauki fenofibrate daidai. Wannan zai taimaka umarni don amfani, wanda ya ba da shawarar:

1. Takeauki allunan a ciki ba tare da tauna da ruwa ba.
2. Magungunan yana shan giya sau ɗaya a rana, yana haɗa haɗarinsa tare da ci abinci (don haka ya fi dacewa a sha).
3. A sashi na miyagun ƙwayoyi domin daban-daban pathologies ne 145 MG kowace rana. Marasa lafiya tsofaffi ba sa buƙatar gyaran kashi.

Ya kamata a ɗauka Fenofibrate na dogon lokaci. A wannan yanayin, dole ne a lura da abinci na hypocholesterol na musamman.

Bayan wani lokaci (kusan watanni 3 bayan farawar magani), ya kamata a bincika jinin mai haƙuri don ganin ingantaccen kuzari. Idan ba a lura da wannan ba, kuna buƙatar daidaita sashi ko canza tsarin magani.

Hulɗa da ƙwayoyi

Za'a iya amfani da maganin a cikin haɗin kai tare da nisa daga dukkanin magunguna. Ga wasu misalai na hulɗa da sauran magunguna:

1. Tare da gudanarwa na lokaci daya tare da maganin hana daukar ciki, ana inganta tasirin su. Wannan na iya haifar da zub da jini. Idan kana buƙatar amfani da su a lokaci guda, to za a rage yawan maganin anticoagulants sau 3.
2. Fenofibrate tare da cyclosporine, lokacin da aka ɗauka tare, yana tsokani ɓarkewar aikin koda.
3. Amfani da kai tare da sauran fibrates yana kara haɗarin haɓakar lalacewa ga ƙwayoyin tsoka.

Umarni na musamman

Yana da mahimmanci a bincika umarni na musamman kafin amfani da magani. Daga cikinsu akwai:

1. Magungunan ba shi da tasiri idan ba ku rabu da cututtukan da ke haifar da karuwa a cikin yawan ƙwayar lipid ba.
2. Lokacin shan magani, ya kamata ku bi tsarin abinci tare da ƙaramar abubuwan cholesterol.
3. Ana iya tantance tasirin magani ta hanyar sakamakon gwajin jini don abubuwan da ke cikin jimlar cholesterol, LDL, triglycerides.
4. Idan mara lafiya yana shan magungunan hormonal, to ya kamata ka gano idan karuwa a cikin matakan lipid ba sakamakon rashin daidaituwa na hormonal ba.
5. A cikin shekarar farko ta shan maganin, ana bada shawara don saka idanu kan matakan jigilar hepatic (ALT da AST).

Matsayi na AlT da AST

Irin waɗannan matakan na iya haɓaka tasiri na miyagun ƙwayoyi, tare da hana yiwuwar haɓakar halayen marasa kyau da rikitarwa.

Sakamakon sakamako, yawan alamun bayyanar cututtuka

Magani yana da isasshen sakamako masu illa. Yawancin lokaci suna tashi saboda rashin amfani da shi. A wannan yanayin, marasa lafiya na iya fuskantar:

• matsalolin narkewa, wanda ana nunawa ta hanyar tashin zuciya, amai, amai, zafin ciki, zawo,
• maganin ciwon huhu
• samuwar duwatsu a cikin bile bututu,
• ci gaban hepatitis (bayyanuwar cutar ta jaundice, itching fata),
• spasm, rauni na tsoka da rauni,
• haɓaka fararen ƙwayoyin jini da haemoglobin,
• ciwon kai
• take hakkin aikin jima'i,
• thromboembolism, leukocytosis,
• m renal gazawar
• Tsarin kumburi a cikin huhu
• asarar gashi
• rashin lafiyan halayen ga fata a cikin nau'i na redness, itching, rashes, urticaria,
• daukar hoto.

Yawan abin sama da ya kamata yana da wuya. A wannan yanayin, ya kamata a kai mara lafiya zuwa asibiti. Suna gudanar da aikin tiyata. Ba shi yiwuwa a cire maganin ta hanyar maganin hemodialysis.

Irin wannan hanya

Fenofibrate yana nufin wakilan hypoglycemic. Tsarin analogues na tsarinsa yana dauke da abu guda mai aiki. Mafi mashahuri daga gare su:

1. Tricor magani ne mai tsada, amma ingantaccen magani ne daga Faransa.
2. Lipantil shine samfurin Faransa wanda ya ƙunshi 200 MG na fenofibrate a cikin kwamfutar hannu 1.
3. Exlip magani ne na Turkawa wanda ya ƙunshi 250 MG na fenofibrate.

Wasu kwayoyi sun ƙunshi wasu abubuwan haɗin, amma suna da irin wannan sakamako. Daga cikinsu akwai:

1. Atorvacor. Magungunan yana dauke da sinadarin atorvastatin mai aiki kuma mai hanawa ne na HMG-CoA reductase. Ana amfani dashi don hyperlipidemia.
2. Livostor. Hakanan samfurin ya ƙunshi atorvastatin. Magani ne mai rahusa mara nauyi don rage cholesterol jini.
3. Tulip Kamfanin sarrafa magunguna na Sandoz ne a Poland. Atorvastatin yana aiki azaman abu mai aiki.

Ana amfani da irin waɗannan kudade don rashin haƙuri don fenofibrate. Sanya ɗaya ko wani analog na iya halartar likita.

Nazarin likitoci da marasa lafiya

Don kimanta tasiri na miyagun ƙwayoyi, yana da mahimmanci a san abin da likitoci da masu haƙuri suke faɗi game da Fenofibrate. Ga wasu dubai na hakika:

Magungunan Fenofibrate magani ne mai inganci don magance cututtukan cututtukan zuciya. Amfanin sa ya ta'allaka ne ga tarin abu mai aiki a cikin jini, wanda ke haifar da sakamako mai ɗorewa - raguwa a cikin LDL da triglycerides.

Yadda ake ɗaukar Fenofibrate

Allunan ana shan su ba tare da taunawa ba. Marasa lafiya tsofaffi suna buƙatar ɗaukar kashi 145 na magani a rana. Lokacin juyawa daga sashi na 165, 180 MG zuwa kashi na yau da kullun na 145 MG, ba a buƙatar ƙarin gyaran tsarin yau da kullun ba.

Ana shawarar miyagun ƙwayoyi don ɗaukar dogon lokaci a kan asalin tsarin ilimin abinci da ya dace. Ya kamata likitan da ke halartar aikin su tantance tasirin magani a kai a kai gwargwadon yawan abubuwan da ke cikin magani.

Allunan ana shan su ba tare da taunawa ba.

Tsarin juyayi na tsakiya

Rashin daidaituwa da ciwon kai na iya faruwa tare da sakamako masu guba akan tsarin mai juyayi.

Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako mai illa na iya bayyana a cikin yanayin seizures.
Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako na gefen na iya bayyana a cikin nau'in ciwon tsoka.
Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako na iya bayyana a cikin nau'i na fitsari a fata.
Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako mai illa na iya bayyana a cikin hanyar karuwar taro na farin jini a cikin jini.
Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako mai illa a cikin nau'in zawo na iya bayyana.
Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako na gefen na iya bayyana a cikin nau'i na amai.
Tare da sashi ba daidai ba na miyagun ƙwayoyi, sakamako mai illa na iya bayyana a cikin asarar gashi.

Daga tsarin kare jini

Babu wasu canje-canje mara kyau a cikin aikin tsarin urinary.

A mafi yawancin halayen, fatar fata, daukar hoto (tsinkaye ga haske), itching ko amya mai rauni zuwa matsakaici mai rauni. A cikin lokuta mafi wuya, asarar gashi, bayyanar erythema, blisters ko nodules of connective tissue a ƙarƙashin rinjayar radiation ultraviolet.

Tasiri kan ikon sarrafa abubuwan inji

Faukar Fenofibrate baya shafar maida hankali, halayen jiki da psychoemotional, sabili da haka, a lokacin kulawa da rage ƙarfin lipid, fitar da mota da aiki tare da na'urori masu rikitarwa.

A lokacin shan magani, an yarda da tuki mota da aiki tare da na'urori masu rikitarwa.

Yi amfani da lokacin daukar ciki da lactation

A cikin karatun asibiti a cikin dabbobi, ba a sami tasirin teratogenic ba. A cikin karatuttukan gwaji na yau da kullun, magungunan mai guba ga jikin mahaifiyar da haɗarin tayin an yi su, saboda haka, magungunan za a ɗauka ne kawai idan ingantacciyar tasiri ga mace mai ciki ta zarce haɗarin rashin maye na cikin jikin yaro.

Shayar da jarirai a yayin jiyya an soke ta.

Adana Fenofibrate ga Yara

Ba'a ba da shawarar miyagun ƙwayoyi ga yara da matasa masu shekaru 18 ba saboda ƙarancin bayani game da tasirin Fenofibrate akan girma da haɓaka jikin mutum.

Ba'a ba da shawarar miyagun ƙwayoyi ga yara da matasa masu shekaru 18 da haihuwa.
Shayar da jariri a yayin jiyya tare da miyagun ƙwayoyi.
Shan magungunan yayin daukar ciki ana aiwatar da ita ne kawai idan kyakkyawan sakamako ga mace mai ciki ya zarce hadarin rashin lafiyar mahaifa a cikin yarinyar.

Yawan abin sama da ya kamata

Babu wanda ya kamu da cutar yawan maye saboda shan muggan kwayoyi. Babu takamaiman takamaiman abin ƙi. Sabili da haka, idan mara lafiya tare da guda ɗaya na babban kashi ya fara jin ciwo, mummunan yanayin ko tasirin sakamako ya faru, ya zama dole don neman taimakon likita. Tare da asibiti, ana cire alamun bayyanar cutar ta rashin ƙarfi.

Yin hulɗa tare da wasu kwayoyi

Lokacin da ake haɗa fenofibrate tare da maganin rage zafin jiki don gudanar da maganin baka, tasirin magungunan da ake tambaya yana ƙaruwa. Tare da wannan hulɗa, haɗarin zub da jini yana ƙaruwa saboda ƙaurawar anticoagulant daga sunadaran jini na jini.

Tare da yin amfani da layi daya na amfani da abubuwan hanawa na Hkey-CoA reductase, haɗarin tasirin mai guba mai mahimmanci akan ƙwayoyin tsoka yana ƙaruwa, don haka idan mai haƙuri ya ɗauki statins, ya zama dole a soke maganin.

Cyclosporine yana ba da gudummawa ga lalata kodan, don haka lokacin ɗaukar Fenofibrate, dole ne a kai a kai ka bincika yanayin jikin. Idan ya cancanta, an soke aikin maganin maganin cututtukan jini.

Amfani da barasa

Yayin yin jiyya tare da Fenofibrate, an haramta shi sosai don shan giya. Ethyl barasa yana raunana tasirin magani na ƙwayar cuta, yana inganta sakamako mai guba akan ƙwayoyin hanta, tsarin juyayi na tsakiya da zaga jini.

Analogues na miyagun ƙwayoyi sun haɗa da kwayoyi tare da kayan aikin iri ɗaya:

• Tricor
• Atorvacor
• Lipantil
• Sabin Shafi,
• Canon Fenofibrate Allunan,
• Livostor
• Bugawa,
• Trilipix.

Sauyawa zuwa wani magani ana yin shi ne bayan tattaunawar likita.

Koyarwar Tricor Lipantil 200 M umarnin Phenofibrate CANON koyarwa

Yanayin ajiya na miyagun ƙwayoyi

An bada shawara don adana miyagun ƙwayoyi a yanayin zafi har zuwa + 25 ° C a cikin wuri mai bushe, wanda yake nesa da hasken rana.

An bada shawara don adana miyagun ƙwayoyi a yanayin zafi har zuwa + 25 ° C a cikin wuri mai bushe, wanda yake nesa da hasken rana.

Batun sakewa Fenofibrate

Akwai maganganun ƙarfafawa daga masana magunguna da marasa lafiya.

Olga Zhikhareva, likitan zuciya, Moscow

Inganci a cikin yaki da high triglycerides. Ina bayar da shawarar amfani da nau'ikan IIa, IIb, III da IV hyperlipoproteinemia. A cikin aikin asibiti, Ina wajabta tsawon lokacin kulawa da sashi akan kowane mutum. Ba a lura da wata illa ba. Ba shi da tasirin magana kan rage yawan cholesterol.

Prokhorov na Afanasy, masanin abinci, Yekaterinburg

Tare da kiba da kuma babban cholesterol, fenofibroic acid yana taimakawa sosai. Musamman tare da ƙarancin ƙarfin motsa jiki da abinci. A lokacin kulawa, Ina ba da shawarar barin kyawawan halaye kuma ku bi shawarar likita sosai don ƙara tasiri.

Nazar Dmitriev, dan shekara 34, Magnitogorsk

Kyakkyawan magani. Lipids sun kasance 5.4. Tare da yin amfani da Fenofibrate na yau da kullun, matakin mai ya ragu zuwa 1.32. Borderline ya kasance 1.7. Babu sakamako masu illa da aka lura.

Anton Makaevsky, mai shekara 29, St. Petersburg

Ya dauki kusan shekara guda a maimakon Torvacard saboda ƙarancin abun ciki na HDL. Bayan watanni 4-5 na gudanarwa, hare-hare na tashin zuciya da jin zafi a saman ciki ya fara bayyana. Bayan watanni 8-9, sun yi aikin tiyata don cire ƙwayar ƙwayar ciki. Viscous bile da sako-sako da duwatsu an samo su. Bayan aikin, an dakatar da kai harin.

Mikhail Taizhsky, mai shekara 53, Irkutsk

Miyagun ƙwayoyi sun sha don ƙarfafa ganuwar jijiyoyin bugun jini, amma ba zan iya faɗi game da aikin ba. Ba a jin muryar kumbura. Tare da taimakon miyagun ƙwayoyi, nauyi ya ragu saboda yunwar, amma fatar ta yi rawa sosai. Ana buƙatar aiki don dawo da aiki. Na gamsu da sakamakon.