Yadda za a yi amfani da miyagun ƙwayoyi Rosinsulin M?

Dakatarwa ga s / c sarrafa farin launi, lokacin da ya tsaya, dakatarwar ta zauna. Ruwan da yake sama da hazo shine tabbatacce, mara launi ko kusan launi. A sauƙaƙe za a sake tura shi cikin saurin girgiza kai.

Fitowa: protamine sulfate 0.12-0.20 mg, sodium hydrogen phosphate dihydrate 0.26 mg, crystalline phenol 0.65 mg, metacresol 1.5 MG, glycerol (glycerin) 16 mg, ruwa d / kuma har zuwa 1 ml.

5 ml - kwalabe (5) - fakitin bakin ciki (aluminum / PVC) (1) - fakitoci na kwali.
10 ml - kwalabe (1) - fakitoci na kwali.
3 ml - katakarar katako (5) - marufi firinji (aluminum / PVC) (1) - fakitoci na kwali.

Aikin magunguna

Haɗin Rosinsulin M 30/70 shiri ne na insulin-matsakaici. Abun da ke cikin miyagun ƙwayoyi ya haɗa da insulin mai narkewa (30%) da insulin-isophan (70%). Insulin yana hulɗa da takamaiman mai karɓa a kan ƙwayar cytoplasmic na sel kuma yana samar da hadaddun insulin-receptor. Ta hanyar kunnawar biosynthesis na CAMP (a cikin ƙwayoyin mai da ƙwayoyin hanta) ko, kai tsaye shiga cikin tantanin halitta (tsokoki), hadaddiyar insulin-receptor tana ƙarfafa ayyukan cikin ciki, gami da kira na enzymes masu yawa (hexokinase, pyruvate kinase, glycogen synthase, da sauransu). Raguwar glucose a cikin jini yana faruwa ne saboda karuwa a cikin jijiyoyin zuciya, karɓar karɓar ƙwaƙwalwa da ƙimar kyallen takarda, haɓakar lipogenesis, glycogenogenesis, ƙwayar furotin, raguwa a cikin yawan samar da glucose ta hanta, da dai sauransu.

Matsakaicin aikin aiwatar da shirye-shiryen insulin shine mafi yawanci saboda yawan sha, wanda ya dogara da dalilai da yawa (alal misali, akan kashi, hanyar da wurin gudanarwa). Sabili da haka, bayanan bayanan aikin insulin yana ƙarƙashin mahimman canzawa, duka mutane daban-daban da kuma mutum ɗaya.

A matsakaici, bayan sc gwamnati, Rosinsulin M mix 30/70 fara aiki a cikin awanni 0.5, matsakaicin sakamako yana haɓaka cikin kewayon daga 4 zuwa 12 sa'o'i, tsawon lokacin aikin yana zuwa 24 hours.

Alamun magungunan Rosinsulin M hade 30/70

• type 1 ciwon sukari a cikin manya,
• nau'in ciwon sukari na 2: matakin tsayayya da wakilai na bakin jini, juriya ga waɗannan kwayoyi (yayin haɗuwa da jiyya), cututtukan cikin zuciya.

Sakawa lokacin

Haɗin Rosinsulin M 30/70 yana nufin sc gwamnati. Yawan maganin yana maganin likita ne daban-daban a kowane yanayi, gwargwadon yawan glucose a cikin jini. A matsakaici, kashi na yau da kullum na miyagun ƙwayoyi ya tashi daga 0 to 1 IU / kg nauyin jiki, gwargwadon halayen mutum na haƙuri da haɗuwa da glucose a cikin jini.

Zazzabi na insulin da ke cikin yakamata ya zama zazzabi a dakin. Kafin amfani, dakatarwar an haɗu a hankali har sai uniform. Haɗin Rosinsulin M sau 30/70 yawanci ana allurar sc a cikin cinya. Hakanan za'a iya yin allura a cikin bangon ciki na ciki, gindi ko kafada a cikin tsinkayar tsoka mai narkewa.

Wajibi ne don canja wurin allurar a cikin yankin na jikin mutum don hana haɓakar lipodystrophy.

Side sakamako

Sakamakon tasirin metabolism: yanayin hypoglycemic (pallor na fata, karuwar gumi, palpitations, rawar jiki, yunwar, tashin hankali, paresthesia a cikin bakin, ciwon kai). Mai tsananin rashin ƙarfi na hypoglycemia na iya haifar da haɓakar ƙwaƙwalwar ƙwayar cuta.

Allergic halayen: da wuya - fatar fata, fitsarin Quincke, mai wuya sosai - girgiza anaphylactic.

Abubuwan da suka shafi gida: hyperemia, kumburi da itching a wurin allurar, tare da tsawan amfani - lipodystrophy a wurin allurar.

Sauran: edema, kurakurai na yau da kullun kurakurai (yawanci a farkon farji).

Haihuwa da lactation

Babu ƙuntatawa game da lura da ciwon sukari mellitus tare da insulin yayin daukar ciki, saboda insulin baya ƙetare shingen ƙarfe. Lokacin da ake shirin daukar ciki da lokacin sa, ya zama dole a kara yin maganin cutar sankara. Bukatar insulin yawanci yana raguwa a farkon farkon ciki kuma sannu a hankali yana ƙaruwa a cikin na biyu da na uku.

Lokacin kuma kai tsaye bayan haihuwa, buƙatun insulin na iya raguwa kwatsam. Jim kaɗan bayan haihuwa, buƙatar insulin da sauri ya koma matakin da ya kasance kafin yin juna biyu. Babu ƙuntatawa game da lura da ciwon sukari mellitus tare da insulin yayin shayarwa. Koyaya, yana iya zama mahimmanci don rage adadin insulin, sabili da haka, saka idanu a hankali na watanni da yawa ya zama dole kafin a inganta buƙatar insulin.

Umarni na musamman

Kafin amfani, a hankali bincika bayyanar abubuwan da ke cikin kwalbar kuma kada kuyi amfani da kayan haɗin Rosinsulin M 30/70 idan, bayan haɗuwa, dakatarwar ta ƙunshi flakes ko kuma idan farin barbashi ya bi zuwa kasan ko ganuwar kwalbar, ƙirƙirar tasirin yanayin sanyi.

Kada kuyi amfani da kayan haɗin Rosinsulin M 30/70 idan, bayan girgizawa, dakatarwar ba ta zama fari ba kuma gajimare.

A waje da tushen ilimin insulin, kulawa akai-akai na maida hankali kan glucose jini yana da muhimmanci.

Abubuwan da ke haifar da cutar rashin ƙarfi a cikin jiki a haɗe da yawan ƙwayar insulin na iya zama: maye gurbin miyagun ƙwayoyi, tsallake abinci, amai, zawo, damuwa na jiki, cututtukan da ke rage buƙatar insulin (lalacewar hanta da ƙwaƙwalwar hanji, hauhawar huhun ciki, huhu ko glandar thyroid), canjin wurin allura, da kuma hulɗa tare da wasu kwayoyi.

Rashin ingantaccen allura ko katsewa a cikin gudanarwar insulin, musamman a cikin marasa lafiya da ke dauke da ciwon sukari na 1, na iya haifar da cutar hauka. Yawancin lokaci, alamun farko na hyperglycemia suna haɓaka hankali a kan sa'o'i da yawa ko kwanaki. Waɗannan sun haɗa da ƙishirwa, yawan urination, tashin zuciya, amai, amai, ja, bushewar fata, bushewar baki, rashin ci, kamshin acetone a cikin iska mai ƙuna. Idan ba a kula da shi ba, zazzabin hyperglycemia a cikin nau'in 1 na ciwon sukari na iya haifar da haɓakar cutar ketoacidosis mai barazanar rayuwa. Yawan maganin insulin dole ne a gyara shi saboda aikin thyroid mai rauni, cutar Addison, cututtukan zuciya, hanta da aikin koda, da kuma cututtukan sukari a cikin mutane sama da shekaru 65.

Hakanan ana iya buƙatar gyara kashi na insulin idan mai haƙuri ya ƙaru da matakin motsa jiki ko ya canza abincin da aka saba.

Cututtukan da ke haɗuwa, musamman cututtuka da yanayi tare da zazzabi, suna ƙara buƙatar insulin.

Gyara daidaitawa da sauyawa daga wani nau'in insulin zuwa wani yakamata a gudanar dashi karkashin kulawar likita da kuma lura da yawan haɗuwar glucose a cikin jini. Miyagun ƙwayoyi na rage haƙuri haƙuri.

Sakamakon yiwuwar hazo a cikin wasu catheters, ba a bada shawarar yin amfani da miyagun ƙwayoyi a cikin farashin matatun.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Dangane da babban dalilin insulin, canji a nau'ikansa ko kasancewar mahimman damuwa na jiki ko na tunani, yana yiwuwa a rage ikon hawa mota ko sarrafa abubuwa daban-daban, kazalika da shiga cikin wasu ayyukan haɗari masu haɗari waɗanda ke buƙatar haɓakar kulawa da saurin halayen tunani da motsa jiki.

Yawan abin sama da ya kamata

Bayyanar cututtuka: tare da yawan shaye-shaye, hypoglycemia na iya haɓaka.

Jiyya: mai haƙuri na iya kawar da ɗimbin ƙwayar cuta mai narkewa ta hanyar shigar da sukari ko abinci mai cike da carbohydrate. Sabili da haka, an ba da shawarar ga marasa lafiya masu ciwon sukari don ɗaukar sukari, Sweets, cookies ko ruwan 'ya'yan itace mai dadi tare da su. A cikin lokuta masu tsauri, lokacin da mara lafiya ya rasa hankali, ana gudanar da maganin 40% na iv
dextrose (glucose), a cikin / m, s / c, in / in - glucagon. Bayan ya dawo da hankali, ana ba da shawarar mai haƙuri ya ci abinci mai arzikin carbohydrate don hana sake haɓakar ƙwanƙwasa jini.

Hulɗa da ƙwayoyi

Akwai magunguna da yawa waɗanda ke shafar buƙatar insulin. Hypoglycemic sakamako na insulin inganta baka hypoglycemic kwayoyi, Mao hanawa, ACE hanawa, carbonic anhydrase hanawa, zabe beta-blockers, bromocriptine, octreotide, sulfonamides, anabolic steroids, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, theophylline, cyclophosphamide, fenfluramine, lithium shirye-shirye shirye-shirye dauke da ethanol.

Hypoglycemic sakamako na insulin sosai baka hana, corticosteroids, thyroid hormone, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazol, clonidine, alli tashar blockers jinkirin, diazoxide, morphine, phenytoin, nicotine, sulfinpyrazone, epinephrine, histamine H 1 tsoka mai amsa sigina.

Underarfafawar tasirin reserpine da salicylates, duka raunana da haɓaka a cikin aikin miyagun ƙwayoyi yana yiwuwa.

Yadda ake amfani: sashi da hanya na jiyya

Magungunan an yi niyya ne don gudanar da aikin jinƙai na cikin ƙasa. Yawan maganin yana maganin likita ne daban-daban a kowane yanayi, gwargwadon yawan glucose a cikin jini. A matsakaici, yawan maganin yau da kullun ya tashi daga 0.3 zuwa 1 IU / kg nauyin jikin mutum, ya dogara da yanayin halayen mutum na haƙuri da haɗuwa da glucose a cikin jini.

Bukatar yau da kullun don insulin na iya zama mafi girma a cikin marasa lafiya tare da juriya na insulin (alal misali, yayin balaga, har ma a cikin marasa lafiya tare da kiba), da ƙananan a cikin marasa lafiya tare da ragowar insulin na insulin.

Zazzabi na insulin da ke cikin yakamata ya zama zazzabi a dakin. Kafin amfani, dakatarwar an haɗu a hankali har sai uniform. Yawancin lokaci ana ba da maganin a ƙarƙashin cinya. Hakanan za'a iya yin allura a cikin yankin bangon baya na ciki, gindi da gindi ko kuma a cikin yanki na ƙwayar tsoka ta kafada. Tare da gabatarwar miyagun ƙwayoyi a cinya, akwai jan hankali a hankali fiye da lokacin da aka gabatar da shi zuwa wasu yankuna.

Wajibi ne a canza wurin allura a koyaushe a cikin yankin ilmin jikin don hana haɓakar lipodystrophy.

Lokacin amfani da pre-cika disposable allurai sirinji alkalami da yawa don maimaita injections, ya zama dole don cire alkairin sirinji daga firiji kafin amfani farko da bari likitan ya isa zafin jiki a ɗakin. Wajibi ne a haɗu da dakatarwar ROSINSULIN M Mix 30/70 a cikin abin da za'a iya zubar dashi kai tsaye kafin amfani. Haɗin da aka haɗu da kyau ya kamata ya zama fari da gajimare. Ba za a iya amfani da miyagun ƙwayoyi a cikin alkalami da za'a iya zubar dashi ba idan an daskare shi. Yana da matuƙar mahimmanci ka bi umarnin don amfani da alkairin da aka kawo tare da magani.

Cututtukan da ke haɗuwa, musamman masu kamuwa da cuta tare da zazzabi, yawanci suna ƙaruwa da buƙatar jikin mutum na insulin. Hakanan ana iya buƙatar gyaran gyaran jiki idan mai haƙuri yana da cututtukan ƙwayar cuta na koda, hanta, nakasasshen aikin adrenal, pituitary ko glandar thyroid.

Buƙatar daidaitawa na iya faruwa yayin canzawar aiki na zahiri ko abincin da aka saba samu. Zai yiwu a buƙaci daidaitawa yayin canja wurin mai haƙuri daga nau'in insulin zuwa wani.

Side effects

Babban haɗarin haɗari tare da insulin shine hypoglycemia. A lokacin gwaji na asibiti, kazalika da lokacin amfani da miyagun ƙwayoyi bayan fitarwarsa a kasuwar mabukaci, an gano cewa abin da ya faru na hypoglycemia ya bambanta dangane da yawan masu haƙuri, tsarin shaye-shayen magunguna, da kuma sarrafa glycemic.

A matakin farko na maganin insulin, kurakurai masu narkewa, yatsun farji da halayen a wurin yin allura (gami da jin zafi, redness, urticaria, kumburi, hematoma, kumburi da itching a wurin allura) na iya faruwa. Wadannan alamu yawanci ne na wani lokaci. Ingantaccen haɓakawa a cikin sarrafa glycemic na iya haifar da yanayin 'mummunan ciwo neuropathy', wanda yake sabawa sau da yawa. Intensation na insulin farjin tare da ingantacciyar ci gaba a cikin sarrafa metabolism na metabolism na iya haifar da lalacewa ta ɗan lokaci a cikin yanayin ciwon sukari, yayin da ci gaba na dogon lokaci a cikin kulawar glycemic yana rage haɗarin ci gaban cututtukan ciwon sukari.

Saki siffofin da abun da ke ciki

Dakatarwa ga tsarin mulki na 100 IU / ml yana samuwa ta hanyar:

• kwalban 5 da 10 ml,
• 3 Katin katako.

1 ml na miyagun ƙwayoyi ya ƙunshi:

1. Babban kayan aiki shine insulin kwayoyin halittar mutum 100 IU.
2. Abubuwa masu taimako: protamine sulfate (0.12 mg), glycerin (16 mg), ruwa don allura (1 ml), metacresol (1.5 mg), phenol crystalline (0.65 mg), sinadarin hydrogen phosphate dihydrate (0.25 mg).

Dakatarwar don subcutaneous management na 100 IU / ml ana samun su ta hanyar: kwalban 5 da 10 ml, kwandon shara na 3 ml.

Pharmacokinetics

Cikakkiyar sha da bayyanar tasirin yana dogara ne akan sashi, hanyar da wurin allurar, maida hankali insulin. An lalata miyagun ƙwayoyi ta hanyar aikin insulinase a cikin ƙodan. Zai fara aiki rabin sa'a bayan gudanarwa, ya kai kololuwa a cikin awanni 3-10 a jiki, ya daina aiki bayan kwana 1.

Tsari, abun da ke ciki da tsarin aiki

“Rosinsulin” yana nufin kwayoyi na kungiyar “hypoglycemic jamiái” kungiyar. Ya danganta da gudu da tsawon lokacin aiwatarwa, akwai:

An rage sukari nan take! Ciwon sukari na tsawon lokaci na iya haifar da tarin cututtuka, kamar matsalolin hangen nesa, yanayin fatar da gashi, ulcers, gangrene har ma da cutar kansa! Mutane sun koyar da ƙwarewar haushi don daidaita matakan sukari. karanta a.

• "Rosinsulin S" tare da matsakaicin tsawon lokacin aiki,
• "Rosinsulin R" - tare da takaice,
• “Rosinsulin M” wakili ne mai hade wanda ya kunshi 30% insulin mai narkewa da kashi 70% na insulin-isophan.

Ana samun insulin magani daga jikin mutum ta hanyar canje-canje na DNA. Umarni suna nuna cewa ka'idodin aiki ya samo asali ne daga hulɗa da manyan abubuwan da miyagun ƙwayoyi ke ciki tare da ƙwayoyin sel da kuma hadaddun ginin insulin. Sakamakon haka, haɗin enzymes wanda ya wajaba don aiki daidai na jiki yana faruwa. Normalization na matakan sukari yana faruwa ne sakamakon narkecellular metabolism da isasshen sha. A cewar masana, ana ganin sakamakon aikace-aikacen 1-2 sa'o'i bayan gudanarwa a fata.

"Rosinsulin" shine dakatarwa don gudanarwa a karkashin fata. Wannan aikin ya samo asali ne daga abun cikin insulin-isophan.

A waje, magani yana da fari tare da ɗanɗano launin toka. Idan babu girgizawa, an rabu dashi cikin ruwa bayyananne da kuma hazo. Dangane da umarnin, "Rosinsulin" ya kamata a girgiza shi kafin gudanarwa. Bugu da ƙari, abun da ke cikin miyagun ƙwayoyi ya haɗa da abubuwan da aka bayyana a cikin tebur:

Magungunan Rosinsulin M yana da ikon kula da adadin sukarin da yakamata a cikin jini, da kyautata rayuwa.

Tare da ciwon sukari

Kafin amfani, kuna buƙatar girgiza bayani dan kadan har sai an sami yanayin tururi ɗaya. Mafi sau da yawa, ana sanya allura a cikin cinya, amma kuma an yarda dashi a gindi, kafada ko bangon ciki. An cire jini a wurin allura tare da ulu mai goge fata.

Zai dace a sauya wurin allura domin a hana bayyanar lipodystrophy.An haramta amfani da maganin a cikin alkalami wanda za'a iya zubar dashi idan an daskare shi, ana buƙatar canza allura akai-akai. Ya kamata ya jagorance ta ta hanyar amfani da alkairin sirinji wanda yazo tare da kunshin tare da Rosinsulin M 30/70.

Tsarin Endocrin

Ana nuna cin zarafin a cikin hanyar:

• fata fata,
• wuce kima gumi
• mai sauri ko marasa daidaitaccen bugun zuciya,
• ji na kullum rashin abinci,
• migraines
• kona da tingling a cikin bakin.

A cikin lokuta na musamman, akwai haɗarin cutar rashin daidaituwa na jini.

Halin rashin lafiyan ya nuna kanta a cikin hanyar:

• cututtukan mahaifa
• zazzabi
• karancin numfashi
• angioedema,
• rage karfin jini.

Yi amfani da lokacin daukar ciki da lactation

Babu haramtawa shan magungunan yayin daukar ciki, saboda Abubuwan da ke aiki ba su ƙetare mahaifa. Lokacin shirin yara da ciki, lura da cutar ya kamata ya zama mafi m. A cikin farkon farkon, ana buƙatar ƙarancin insulin, kuma a cikin 2 da 3 - ƙari. Yana da mahimmanci a kula da matakan sukari kuma daidaita sashi daidai.

Yayin shayarwa, babu wasu ƙuntatawa game da amfani da Rosinsulin M. Wasu lokuta ya zama dole don rage sashi, don haka akwai buƙatar kulawa ta lokaci ta likita don watanni 2-3 har sai buƙatar insulin ta koma al'ada.

Yin hulɗa tare da wasu kwayoyi

An inganta tasirin hypoglycemic kuma yana inganta ta:

• mahaifa na baki,
• angiotensin yana sauya masu hana masu enzyme,
• monoamine oxidase
• sulfonamides,
• Mebendazole,
• karafarini
• magunguna dauke da ethanol,
• Kalamunda

Mun gano sakamakon maganin:

• glucocorticosteroids,
• hodar iblis,
• sinadarin nicotine
• Danazole
• Phenytoin
• Sulfinpyrazone,
• Diazoxide
• Heparin.

Abun dacewa

An haramta shan giya da magunguna dauke da giya yayin shan Rosinsulin M. Ikon aiwatar da giya ya ragu. Ethanol na iya haɓaka tasirin ƙwayar, wanda zai haifar da hypoglycemia.

Hanyoyin magunguna masu kama don tasirin sune:

Reviews game da Rosinsulin M

Mikhail, mai shekara 32, babban likita, Belgorod: “Iyayen da yaransu ke fama da ciwon sukari mellitus yawanci suna neman taimako. A kusan dukkanin lokuta, Ina rubuto dakatarwar Rosinsulin M. Na yi la'akari da wannan magani mai tasiri, tare da ƙaramin adadin contraindications da sakamako masu illa, kazalika da farashin dimokiradiyya. ”

Ekaterina, mai shekara 43, masanin ilimin dabbobi, Moscow: “Yaran da ke fama da ciwon sukari lokaci-lokaci suna samun alƙawura. Don ingantaccen, ingantaccen magani mai lafiya, ina kaman allurar da wannan magani. Babu wani gunaguni yayin gudanar da aikin. ”

Julia, 'yar shekara 21, Irkutsk: “Da daɗewa nake ina sayan wannan magani. Faranta masa da sakamako da kuma lafiyar gaba daya bayan shan shi. Ba kasa da takwarorinsu na kasashen waje. An yarda da shi sosai, sakamakon yana dawwama. "

Oksana, dan shekara 30, Tver: “Yayana ya kamu da ciwon sukari mellitus, yayi alƙawura da likitata. A kan shawarwarinsa, sun sayi allura tare da wannan magani. Na yi mamakin kyakkyawan tasiri da kuma farashi mai sauki. "

Wanene aka nada?

Kafin fara magani, dole ne ka nemi likitanka kuma ka ƙayyade dacewar ɗaukar magani. "Rosinsulin" yana nufin shirye-shiryen insulin. An hana shi sayen da kuma amfani da magani ba bisa ƙa'ida ba saboda yawan yiwuwar sakamako mara kyau. Likitocin sun bada shawarar shan maganin idan akwai alamun cutar a cikin umarnin:

• nau'in 1 ko nau'in ciwon sukari na 2
• ciwon sukari mellitus yayin daukar ciki.

Bugu da ƙari, ana iya buƙatar alƙawura a irin waɗannan halaye:

• in babu wani sakamako sakamakon shan wasu cututtukan da ake amfani da su na hypoglycemic,
• a matsayin maganin cudanya na asali,
• a cikin bayan aiki ko bayan aikin.

Umarnin don amfani da "Rosinsulin C"

“Rosinsulin” yana nufin shirye-shiryen gudanarwa ne a fata. Ana amfani da maganin tare da bayyanannun umarni waɗanda ke nuna shawarar da aka bayar, dangane da ganewar asali da kuma haɗuwar glucose a cikin jini. Kafin fara amfani da shi, ya kamata ka ziyarci likita don ƙididdige tsarin kulawa da mutum. Matsakaicin da aka ba da shawarar ya dogara da nau'in magani. 1 ml na dakatarwa ya ƙunshi har zuwa 100 IU. An gabatar da bayanan a cikin teburin: