Allunan kwayar Ovencor: alamomi don amfani, farashi da analog

Ariescore (kwayoyin hana daukar ciki) Rating: 9

Mai masana'anta: Ozone (Russia)
Siffofin Saki:

  • Tab. 10 MG, 20 inji mai kwakwalwa., Farashin daga 372 rubles
  • Tab. Mita 20, guda 20., Farashin daga 510 rubles
Farashin farashi mai kyau a cikin kantin magani na kan layi
Umarnin don amfani

An samar da miyagun ƙwayoyi a Rasha, wanda aka yi niyya don maganin cututtukan cututtukan zuciya. Abubuwan da ke aiki shine simvastatin a cikin adadin 10 ko 20 MG kowace kwamfutar hannu. Contraindicated a karkashin shekara 18 years.

Analogs na miyagun ƙwayoyi Ariescor

Analog mai rahusa daga 313 rubles.

Mai masana'anta: Vertex (Russia)
Siffofin Saki:

  • Allunan 10 MG, inji mai kwakwalwa 15, Farashi daga 59 rubles
  • Allunan 10 MG, 30 inji mai kwakwalwa., Farashin daga 62 rubles
Farashin Simvastatin a cikin kantin magani na kan layi
Umarnin don amfani

Simvastatin magani ne na rage zafin jiki na samar da kasar Rasha. Ana samunsa ta hanyar Allunan kuma yana ɗauke da abu guda aiki a cikin sashi na 10 zuwa 40 MG. Nuna don amfani dashi don maganin cututtukan cututtukan zuciya.

Analog mai rahusa daga 173 rubles.

Mai masana'anta: Krka (Slovenia)
Siffofin Saki:

  • Allunan 20 MG, inji mai kwakwalwa 14, Farashi daga 199 rubles
  • Allunan 10 MG, guda biyu., Farashin daga 289 rubles
Farashin Vasilip a kan magunguna na kan layi
Umarnin don amfani

Morearin maye gurbin Slovenian mafi riba mai riba tare da wannan nau'in sakin da kuma abubuwan abubuwa masu aiki. Babban alamomi don amfani: hypercholesterolemia na farko ko hadewar dyslipidemia, raguwar mace-mace da jijiyoyin jini a cikin marasa lafiya tare da alamun bayyanar cututtuka na cututtukan zuciya na atherosclerotic ko ciwon sukari mellitus. Akwai contraindications.

Analog ne mai rahusa daga 265 rubles.

Mai masana'anta: Gideon Richter (Romania)
Siffofin Saki:

  • Tab. 10 MG, pcs 14, Farashin daga 107 rubles
  • Tab. 10 mg, 28 inji mai kwakwalwa., Farashin daga 202 rubles
Farashin Simvastol a cikin kantin magani na kan layi
Umarnin don amfani

Simvastol shine kwatankwacin samarwa da Romaniyanci. Akwai shi a cikin kwali na kwali na 14 da allunan. Abunda yake aiki iri ɗaya ne a nan, saboda haka umarnin amfani kawai ya ƙunshi ƙananan bambance-bambance. Kafin fara magani, muna bada shawarar sosai ga likita.

Formaddamar da tsari da abun da ke ciki

Sigar nau'in sakin Ovenkor - allunan da aka rufe: fararen, biconvex zagaye 10 (30 ko guda 30) A cikin blisters, a cikin kwali na 10, 20, 40, 60, 80 da 100 fakitoci, 10, 14, 20, 28, 30, 40, 50 ko kwamfutoci 100. A cikin kwantena na polymer, a cikin kwali na kwali 1).

Abun ciki 1 kwamfutar hannu:

  • abu mai aiki: simvastatin - 10 ko 20 mg,
  • abubuwan taimako: polyethylene glycol-4000, talc, titanium dioxide, castor oil, butyl hydroxyanisole, microcrystalline cellulose, ascorbic acid, lactose, citric acid, masara da pregelatinized starches, magnesium stearate, hydroxypropyl methylcellulose.

Pharmacodynamics

Magungunan daga rukuni na statins, yana da tasirin lipid, yana hanawa HMG-CoA reductase. Tsarinta yana da rufaffiyar magana zobe na lactone, wanda aka samar da ruwa mai narkewa a jikin dan Adam, wato, prodrug ne.

Lactone zobe statins yana da alaƙa da enzyme HMG-CoA reductasea sakamakon abin da yake ɗaure shi da ƙarfi zuwa wani ɓangare na mai karɓa coenzyme AInda wannan enzyme ya danganta.

Wani sashi na satin kwayar halitta yana cikin aikin juyawa hydroxymethylglutarate a mevalonatewanda ya danganci samfur na matsakaitan kwayoyi cholesterol. Wadannan hanyoyin suna haifar da halayen da yawa, sakamakon wanda abun cikin ke ciki cholesterol ragewa da haɓakar ƙwayar cholesterol catabolism LDL. Tasirin rage rage karfin maganin yana haifar da raguwar jimlar kwayoyi saboda yawan kwayoyi LDL. A lokaci guda, raguwa a matakin LDL kashi-dogara da kuma shi ne tabbatacce.

Statins ba su shafi catabolism da hadaddun kitse na mai, don haka suna shafar matakin TG a kaikaice (na biyu). Dangane da binciken, miyagun ƙwayoyi suna haɓaka matakin HDL cholesterol har zuwa 14%. Baya ga tasirin lipid, ƙwayar tana da tasiri mai kyau a kan bangon jijiyoyin bugun gini yayin lalacewar endothelial (alama ce ta ainihin lokacin farkon atherosclerosis), yana daidaita abubuwan da ke tattare da rheological jini, kuma yana da maganin rigakafi da tasirin antioxidant. Jiyya tare da miyagun ƙwayoyi yana haɗuwa tare da rage yawan tasirin cututtukan zuciya.

Pharmacokinetics

Simvastatin yana da babban sha. Matsakaicin mafi yawan hankali a cikin jini bayan an shigar da ƙarfi bayan awa 1.3-2.4, bayan awanni 12 ya rage da kashi 90%. Sadarwa tare da ƙwayoyin plasma kusan 95%.

Yana da tasirin nassi na farko ta hanta: hydrolysis tare da ƙirƙirar beta-hydroxyacid mai aiki, kuma an sami sauran metabolites masu aiki da marasa aiki.

Rabin rayuwar rayuwa metabolites shine 1.9 hours.

An keɓe shi musamman a cikin hanyar metabolites tare da feces (60%). A cikin yanayin rashin aiki, kusan kodan na 10-15% ne ya raba ta da kodan.

Alamu don amfani

  • hypercholesterolemia: hypercholesterolemia na farko (nau'in IIa da IIb) a cikin marasa lafiya tare da haɗarin haɓakar haɓakar atherosclerosis a cikin yanayin rashin abinci mai amfani tare da ƙananan ƙwayar cuta da sauran matakan rashin magunguna (asarar nauyi da aiki na jiki), haɗuwa da hypercholesterolemia da hauhawar jini, waɗanda ba a daidaita musamman ba. da kuma aiki na zahiri,
  • IHD (cututtukan zuciya na zuciya): don hana infarction na zuciya, rage hadarin cututtukan zuciya (bugun jini ko tashin hankali ischemic), mutuwa, hanyoyin farfadowa, da kuma rage ci gaba da jijiyoyin zuciya arteriosclerosis.

Contraindications

  • cutar hanta a cikin aiki aiki, mai karuwa a cikin ayyukan hanta enzymes na asalin da ba a sani ba,
  • porfria
  • ciwon kai
  • shekaru zuwa shekaru 18
  • ciki da lactation,
  • rashin haƙuri na kowane ɓangare na miyagun ƙwayoyi, har ma da sauran magungunan statin (HMG-CoA reductase inhibitors) a cikin tarihi.

Zumunta (an nada Ovenkor karkashin kulawar likita):

  • yawan shan ruwa sosai
  • jijiyoyin jini, cututtukan matsananciyar cuta, mummunan cuta na endocrine / cuta, rashin daidaituwa na ruwa, raunin da ya faru, raunin cikin gida (gami da hakori) ko wasu yanayi wanda za'a iya samun ci gaba na lalacewa ta koda,
  • yanayi bayan dasawar kwayoyin halitta yayin aikin rigakafi (hade da haɓakar haɓakar haɓakar renal da rhabdomyolysis),
  • fargaba
  • runtse / ƙara sautin ƙwaƙwalwar ƙwaƙwalwar asalin asalin da ba a sani ba.

Umarnin don amfani Ovenkor: hanya da sashi

Ana ɗaukar Ovencor a baki sau 1 a rana da yamma, ana wanka da ruwa mai yawa. Lokacin shan miyagun ƙwayoyi bai kamata a danganta shi da cin abinci ba.

Kafin fara amfani da Ovenkor, an wajabta mara lafiya mai cikakken tsarin abinci na hypocholesterol, wanda yakamata a bi a duk lokacin aikin jiyya.

Tare da hypercholesterolemia, kashi na yau da kullun ya bambanta tsakanin 1080 MG.

Matsakaicin farawa don hypercholesterolemia shine 10 MG. Matsakaicin - 80 MG kowace rana. Ya kamata a aiwatar da canje-canje (zaɓi) na kashi a cikin tazara na makonni 4. A cikin mafi yawan lokuta, ana lura da ingantaccen sakamako yayin ɗaukar miyagun ƙwayoyi a cikin adadin yau da kullun zuwa 20 MG.

Tare da maganin hyzycholesterolemia na homozygous, ana yin Ovencor yawanci a cikin 40 MG a cikin kashi 1 ko 80 MG a cikin allurai 3 (20 mg da safe da yamma, 40 mg da yamma).

Ingancin allurai na Ovenkor don cututtukan zuciya ko kasancewar hadarin ci gabanta shine kashi 20-40 a kowace rana. A farkon farawa, ana yin allurar 20 a mafi yawan lokuta, ana iya ƙara kashi tare da hutu na makonni 4. Lokacin da abun ciki na LDL ya zama ƙasa da 75 mg / dl (1.94 mmol / L) kuma jimlar cholesterol ƙasa da 140 mg / dl (3.6 mmol / L), ana rage yawan kashi.

A cikin mafi ƙarancin kashi 10 na MG, Ovencor ya ba da umarnin ƙasa da 30 ml / min a cikin marasa lafiya tare da gazawar ƙwayar ƙwayar ƙwayar cuta na mahaifa (CRF) (keɓancewar creatinine) ko haɗin gwiwa tare da cyclosporine, danazole, gemfibrozil ko wasu fibrates (banda fenofibrate), niacin a lipid low allurai ( har zuwa 1000 MG kowace rana). Tare da amfani da lokaci guda tare da amiodarone ko verapamil, kashi na yau da kullun na Ovenor bai wuce 20 MG ba.

Side effects

  • tsarin narkewa: zafi na ciki, maƙarƙashiya / zawo, amai, tashin zuciya, tashin zuciya, farji, amai, haɓaka aikin hanta enzymes hanta, alkaline phosphatase da CPK (creatine phosphokinase),
  • jijiyoyin jiki da tsarin juyayi: ciwon kai, matsanancin asthenic, neuropathy na gefe, bugun zuciya, rashin bacci, kwanciyar hankali, jijiyoyin wuya, dandano mara kyau, hangen nesa,
  • immunopathological da rashin lafiyan halayen jiki: flailers mai zafi, eosinophilia, hyperemia na fata, arthritis, vasculitis, angioedema, polymyalgia rheumatism, thrombocytopenia, ƙwararrun ESR, farfadowa da magungunan lupus-like syndrome, zazzabi, urticaria, daukar hoto, gazawar numfashi,
  • halayen cututtukan fata: da wuya - dermatomyositis, fatar fata, alopecia, itching,
  • tsarin musculoskeletal: rauni, myopathy, cramps muscle, myalgia, da wuya - rhabdomyolysis,
  • wasu halayen: palpitations, anemia, rage potency, m renal gazawar.

Yawan abin sama da ya kamata

Babu wasu takamaiman bayyanar cututtuka na yawan abin sama da ya wuce Ovenkor (an san lokuta game da shan miyagun ƙwayoyi a cikin kashi 450 mg).

Farfesa: matakan da aka takaita don rage shaye shayen (shigo da amai, shan gawayi), maganin alamomi a karkashin kulawar koda da aikin hepatic, da kuma matakin CPK.

Game da haɓakar rashin lafiyar myopathy tare da rhabdomyolysis da kuma ƙarancin na koda Idan ya cancanta, ana yin hemodialysis.

Rhabdomyolysis na iya haifar da hyperkalemia, wanda aka kawar da shi ta hanyar gudanarwar ciki na alli chloride ko alli gluconate, jiko glucose a hade tare da insulin, musayar ion potassium, ko, a cikin manyan lokuta, ta hanyar hemodialysis.

Umarni na musamman

A farkon farawa, ana iya lura da kumburin kumburi a matakin enzymes na hanta.

Kafin rubuta magani da kuma kullun a nan gaba, ya kamata a gudanar da nazarin ayyukan hepatic. Mitar sa ido akan ayyukan enzymes na hepatic: farkon watanni ukun - kowane sati 6, sannan a lokacin sauran shekara na farko - lokaci 1 cikin watanni biyu, a gaba - lokaci 1 a cikin watanni shida. An kuma gudanar da gwaje-gwaje na aiki don tantance aikin hanta tare da kara allurai. Idan kashi ya haura zuwa 80 MG kowace rana, iko ya kamata a yi sau ɗaya a kowane watanni uku. An daina amfani da Ovenkor a cikin lokuta na ci gaba da karuwa a cikin aikin transaminase (sau 3 idan aka kwatanta da matakin farko).

A lokacin daukar ciki, zubar da magunguna masu rage karfin liba a kan sakamakon tsawan magani na babban maganin rashin amfani da jini bai da tasirin gaske.

Ba a ba da shawarar matan masu haihuwa da waɗanda ba sa amfani da rigakafi don ɗaukar Ovenkor.

Tare da rage yawan aikin thyroid (hypothyroidism) ko kuma gaban wasu cututtukan koda (ƙwayar nephrotic syndrome) tare da haɓaka cholesterol, ya kamata a fara magance cututtukan da ke haifar da cutar.

Amincewa da Ovenkor na iya haifar da haɓakar rashin lafiyar mama tare da abin da ya faru na rhabdomyolysis da gazawar koda.

Idan ana jin zafin da ba a bayyana ba, rauni na tsoka, rauni na tsoka ko ɓacin rai, ya kamata ku nemi shawarar likitanku, musamman idan waɗannan raunin suna tare da zazzabi ko zazzabin cizon sauro. Kasancewa / gano cutar sankara, an daina amfani da ita.

Don bincika abin da ya faru na myopathy, ana bada shawara don auna ƙimar KFK a kai a kai. A cikin bambancin ganewar asali na jin zafi a bayan sternum, shan magani ya kamata a la'akari.

Aries yana da tasiri a cikin hanyar monotherapy kuma idan aka haɗu da su tare da masu bin bile acid.

Likita ya kayyade tsawon lokacin yin magani daban-daban.

Haihuwa da lactation

Dangane da umarnin, Ovenkor yana contraindicated ga mata yayin daukar ciki / lactation.

Akwai iyakantaccen shaida game da ci gaban mahaifa a cikin jarirai waɗanda uwayensu sun sha maganin. Matan da suka isa haihuwa lokacin shan haihuwa suna shan simvastatin yakamata suyi amfani da hanyoyin hana haihuwa. Lokacin da ciki ya faru, an soke Ovenkor nan da nan.

Hulɗa da ƙwayoyi

  • erythromycin, immunosuppressants, telithromycin, clarithromycin, cytostatics, antifungal jami'ai (ketoconazole, itraconazole), nefazodone, fibrates, nicotinic acid a cikin allurai masu yawa, masu kare lafiyar HIV:
  • danazol, cyclosporine, gemfibrozil da sauran fibrates (ban da fenofibrate), niacin, amiodarone, verapamil, diltiazem: hadarin myopathy / rhabdomyolysis,
  • maganin anticoagulants (fenprocoumone, warfarin): haɗarin zub da jini, saka idanu akan coagulability na jini kafin jiyya kuma yawanci ya isa a farkon maganin,
  • digoxin: karuwa a cikin matakin plasma,
  • colestipol, colestyramine: rage bioavailability (zaku iya ɗaukar Ovencor sa'o'i 4 bayan shan waɗannan kwayoyi, yayin da aka lura da haɓakar tasirin ƙari),
  • ruwan 'ya'yan innabi (fiye da 1000 ml a kowace rana): haɓaka haɓakawa a cikin aikin inhibitory na hana ƙwaƙwalwar HMG-CoA a cikin jini (ya kamata a guji haɗuwa).

Misalan Ovenkor sune: Simvalimite, Sinkard, Zorstat, Simvastatin, Holvasim, Simgal, Zokor, Simvor, Simlo, Vasilip, Simvastol.

Bayanin maganin

Aries - Wani wakilin zubar da jini daga rukunin mutum-mutumi, mai hana shi HMG-CoA reductase. Magana ce ta prodrug, saboda tana da kulle lactone a jikinta, wacce take da ruwa sosai bayan shiga jiki.

Tsarin murfin statin lactone yana kama da na ɓangaren ɓangaren enzyme na HMG-CoA. Dangane da ka’idar gwagwarmayar gwagwarmaya, satin kwayar zarratin an sanya wa wani sashi na coenzyme A receptor inda wannan enzyme yake. Wani sashin kwayar halittar statin yana hana canza hydroxymethylglutarate zuwa mevalonate, wani tsaka-tsaki a cikin kwayar kwayar cholesterol. Haramcin ayyukan HMG-CoA reductase yana haifar da jerin abubuwanda suka biyo baya, sakamakon hakan yana haifar da raguwa cikin abubuwan da ke cikin ƙwayar ƙwayar mahaifa da karuwar biyan diyya a cikin ayyukan masu karɓa na LDL kuma, a sakamakon haka, hanzarta catabolism na LDL cholesterol (Xc).

Sakamakon cututtukan jini na jikin mutum yana da alaƙa da raguwa a matakin jimlar cholesterol saboda ƙwayoyin LDL. Ragewar LDL ya dogara da kashi-kashi kuma ba layi bane, amma ingantacce.

Statins ba su shafi ayyukan lipoprotein da hepatic lipases, ba su da tasiri sosai a kan tsarin haɗin gwal da catabolism na kitse mai ƙoshin mai, don haka, tasirin su a matakin TG shine sakandare kuma kai tsaye ta hanyar manyan tasirin su akan rage darajar LDL-C. Rage matsakaici a cikin matakin TG yayin jiyya tare da statins yana da alama yana da alaƙa da bayyana ragowar (apo E) masu karɓa a farfaɗo na hepatocytes da ke da hannu a cikin catabolism na STDs, wanda ya ƙunshi kusan 30% TG.

Dangane da karatun da aka sarrafa, simvastatin yana ƙara matakin HDL-C zuwa 14%.

Baya ga tasirin rage kiba, statins suna da tasirin gaske akan lalatawar ƙwayar cuta (alamomin farkon atherosclerosis), a jikin bango na jijiyoyin jini, yanayin atheroma, inganta ƙirar rheological jini, suna da maganin antioxidant, antiproliferative Properties. Akwai tabbacin cewa simvastatin yana inganta aikin endothelial bayan kwanaki 30 na maganin.

Yin amfani da simvastatin ya kasance tare da raguwa da yawaitar rikicewar cututtukan zuciya, ba tare da la'akari da matakin farko na LDL-C ba.

Jerin analogues


Fom ɗin saki (ta shahara)Farashin, rub.
Aries
Allunan 20 MG, 30 inji mai kwakwalwa.476
Kawa
Mai aiki
Atherostat
Tab. 0,02 A'a 30 (AVVA RUS OJSC / Sti - Med - Sorb OJSC (Russia)232
Tb PO 0.02 A'a 30 (ABVA RUS OJSC / Sti - Med - Sorb OJSC (Russia)232
Vasilip
Tab 10mg N28 Vector (KRKA, D. Sabon wurin / fakitin. Vector (Russia)329.60
Tab 20mg N28 Vector (KRKA, dd. Sabon wuri / fakitin. Vector (Russia)458.20
Tab 40mg N28 (KRKA - Rus LLC (Russia)628.20
Vero-Simvastatin
Zovatin
Zokor
10mg No. 28 shafin (Merck Sharp and Dome, UK. (Ingila))176
Zokor Forte
40mg A'a 14 shafin (Merck Sharp and Dome, UK. (Ingila))458
Tab 40mg N14 (Merck Sharp and Dome, UK (Ingila))519.90
Zorstat
SIMVAHEXAL
Tab 20mg N30 (Hexal AG (Jamus))287.10
Tab 10mg N30 (Hexal AG (Jamus)319.10
Tab 40mg N30 (Hexal AG (Jamus))484.70
Simvakard
Tab 20mg N28 (ZENTIVA a.s. Czech Republic (Czech Republic)172
Tab 10mg N28 (ZENTIVA a.s. Czech Republic (Czech Republic)218.80
10mg A'a 28 tab (Zentiva k.s. (Czech Republic)242
Simvacol
Simvalimite
Simvastatin
10mg A'a 30 tab p / pl. (Borisovsky ZMP OJSC (Belarus)38.60
20mg No. 30 tab p / pl.o (Borisovsky ZMP OJSC (Belarus)47.50
Tab 10mg N30 Alsi (Alsi Pharma ZAO (Russia)53.70
Tab p / pl. Kimanin 20mg N30 Alsi (Alsi Pharma ZAO (Russia)54.50
20mg No. 30 tab p / pl.o AVVA RUS (AVVA RUS OJSC (Russia)68.30
10mg No. 30 tab p / pl.o (Ozone LLC (Russia))89.10
20mg No. 30 tab p / pl.o (Ozone LLC (Russia))113.80
Tab 20mg N30 (Verteks ZAO (Russia)147.60
Tab 10mg N30 (Verteks ZAO (Russia)207.30
Tab 20mg N20 (Hemofarm A.D. (Serbia)257.30
Simvastatin alkaloid
10mg A'a 28 tab p / pl. (Alkaloid AO (Macedonia)59.80
Simvastatin Zentiva
10mg A'a 28 tab (Zentiva k.s. (Czech Republic)259.90
20mg A'a 28 tab (Zentiva k.s. (Czech Republic)335
40mg A'a 28 tab p / pl. (Zentiva k.s. (Czech Republic)498.70
Simvastatin Pfizer
Simvastatin Sanofi
Simvastatin * (simvastatin *)
Simvastatin-ALSI
Simvastatin-SZ
Allunan 40 mg, 30 inji mai kwakwalwa. (Arewa Star, Rasha)91
Simvastatin-teva
Simvastatin-kusanin
Simvastatin-Chaikafarma
Simvastatin granules
Simvastol
Tab 10mg N28 (Gideon Richter OJSC (Hungary)197.10
Simvor
Tab na po 40mg No. 30 (Ranbaxi Laboratories Limited (India)60.10
Tab da aka 20mg N30 (Ranbaxi Laboratories Limited (India)282
Simgal
Tab 10mg N28 (Kamfanin magunguna na Aivex s.r.o. (Czech Republic)287
40mg No. 84 shafin (Teva Czech Enterprises s.r.r.o. (Czech Republic)304.40
10mg A'a 28 tab (Teva Czech Enterprises s.r.o. (Czech Republic)321.50
20mg A'a 28 tab p / pl. (Teva Czech Enterprises s.r.r.o (Czech Republic)410
10mg No. 84 tab p / pl. (Teva Czech Enterprises s.r.r.o (Czech Republic)609.90
40mg A'a 28 tab p / pl. (Teva Czech Enterprises s.r.r.o (Czech Republic)678
20mg No. 84 shafin (Teva Czech Enterprises s.r.o. (Czech Republic)870
Tab 40mg N84 (Aivex Pharmaceuticals s.r.o. (Czech Republic)1505
Simlo
Tab 10mg No. 28 (Ipka Laboratories Limited (India)202.90
Tab 20mg N28 (Ipka Laboratories Limited (India)293.60
Simplacor
Syncard
Holvasim

Visitoraya daga cikin baƙo ya ba da rahoton ranar karewa

Har yaushe Ovencor ke ɗauka don jin cewa mai haƙuri yana inganta?
Mahalarta binciken a cikin mafi yawan lokuta bayan kwana 1 suna jin cigaba. Amma wannan na iya zama bai dace da lokacin da zaku inganta ba. Shawarci likitanka na tsawon lokacin da kake buƙatar ɗaukar wannan magani. Tebur da ke ƙasa yana nuna sakamakon binciken a farkon aiwatar da tasiri.
Wakilai%
Kwana 11

Visitoraya daga cikin baƙo ya ba da rahoton alƙawari

Wani lokaci ne mafi kyau don ɗaukar Ovenkor: a kan komai a ciki, kafin, bayan ko abinci?
Masu amfani da yanar gizo galibi suna ba da rahoton shan wannan magani a kan komai a ciki. Koyaya, likita na iya bayar da shawarar wani lokaci. Rahoton ya nuna lokacin da sauran marasa lafiyar da aka yi hira da su suka sha maganin.
Wakilai%
A kan komai a ciki1

Baƙi goma sha bakwai sun ba da rahoton haƙuri

Wakilai%
> Shekaru 6012
70.6%
Shekaru 46-60317.6%
30-45 shekara2

Umarni don amfani

(Simvastatin) Lambar yin rijista: LSR-002033/08
Sunan kasuwanci: Aries

Sunan kasa da kasa mai zaman kansa: Simvastatin * (simvastatin *)

Form sashi: allunan da aka saka wa fim
Abun ciki: 1 fim mai rufe jiki
abu mai aiki: Ariescore - 10 MG ko 20 MG,
magabata: microcrystalline cellulose, lactose (sukari madara), sitaci preculatinized sitaci (sitaci 1500), sillofon silicon dioxide (aerosil), acid ascorbic, butylhydroxyanisole, stearic acid, magnesium stearate, opadry II (barasa polyvinyl, black polyglycol, gol iron) iron, iron dye oxide yellow, iron dye oxide ja, titanium dioxide).
Bayanin: allunan biconvex zagaye, mai rufe-fim, daga launin ruwan kasa zuwa launin ruwan kasa mai launin ruwan hoda mai ruwan hoda.
Rukunin Magunguna: wakilin lipid-lowering, HMG-CoA reductase inhibitor.
Lambar ATX: C10AA01

Labari mai ban sha'awa

Yadda zaka zabi analog ɗin da ya dace
A fannin ilimin magunguna, yawanci ana rarraba magunguna zuwa maganganu da analogues. Tsarin kalmomin sun hada da ɗaya ko fiye da waɗannan ƙwayoyin aiki guda ɗaya waɗanda ke da tasirin warkewa akan jiki. Ta hanyar analogs ana nufin magunguna dauke da abubuwa daban-daban na aiki, amma anyi nufin maganin cututtukan guda ne.

Bambanci tsakanin kamuwa da kwayar cuta da kwayan cuta
Kwayoyin cuta suna haifar da ƙwayoyin cuta, ƙwayoyin cuta, fungi da protozoa. Halin cututtukan da ƙwayoyin cuta da ƙwayoyin cuta ke haifar da irin wannan. Koyaya, don bambance abin da ke haifar da cutar yana nufin zaɓin madaidaiciyar magani wanda zai taimaka wajan magance wuyar cutar da sauri kuma ba zai cutar da yaron ba.

Cutar rashin lafiyan shine sanadiyar yawan yawan sanyi
Wasu mutane sun saba da yanayin da yaro sau da yawa kuma na dogon lokaci yana fama da mura. Iyaye suna kai shi wurin likitoci, yin gwaje-gwaje, shan kwayoyi, kuma a sakamakon haka, an riga an yi wa yaro rajista tare da likitan yara kamar yadda ba shi da lafiya. Ba a gano gaskiyar abubuwan da ke haifar da cututtukan numfashi ba.

Urology: lura da chlamydial urethritis
Chlamydial urethritis yawanci ana samun sa a cikin aikin masanin ilimin urologist. Ana haifar dashi ta hanyar Chlamidia trachomatis mai aiki da ƙwayar cuta, wanda ke da kaddarorin ƙwayoyin cuta da ƙwayoyin cuta, wanda yawanci yana buƙatar jigilar maganin rigakafi na dogon lokaci don maganin ƙwayoyin cuta. Yana da ikon haifar da cutar kumburin da ba takamaiman kumburin ciki ba a cikin maza da mata.

Ariescorp, umarnin aikace-aikacen (hanya da sashi)

Kafin farawa tare da Ovencor, an sanya mai haƙuri ma'auni Abincin hypocholesterol. Ya kamata a sha miyagun ƙwayoyi sau ɗaya a rana da yamma, a wanke da ruwa. Tare da ɗaukar abinci, bai kamata a haɗa magungunan ba. Shawarar yau da kullun don magani hypercholesterolemia jere daga 10 zuwa 80 MG. A wannan yanayin, kashi na farko shine 10 MG. Ana yin canje-canje na allurai a jinkirin wata ɗaya. A cikin mafi yawan marasa lafiya, mafi kyawun sakamako mai warkewa yana faruwa lokacin ɗaukar Ovenkor a cikin allurai na yau da kullun har zuwa 20 MG.

Ga marasa lafiya da Ciwon zuciya na Ischemic ko babban haɗarinta na haɓaka ƙwayar magani na yau da kullun shine 20-40 MG, kuma farkon farkon shine 20 MG kowace rana. Ba'a yin gyaran fuska don marasa lafiya bayan shekaru 60 da marasa lafiya tare da gazawar matsakaici mara kyau ko matsakaici. Tare da Ovenkoroma na lokaci daya kuma Aerapamil ko Amiodarone maganin yau da kullun na Ovenkor bai kamata ya wuce 20 MG ba.

Abun ciki, sakin saki

Ariescor shiri ne kawai, ma'ana, ya ƙunshi sashi ɗaya kaɗai mai aiki - simvastatin. Sauran abubuwanda suka rage suna yin aikin taimako: samar da taro, inganta rushewar allunan, dau nauyin dukkan abubuwan juna. A cikin wannan shiri, ana amfani da cellulose, sitaci, ascorbic da citric acid, magnesium stearate, titanium dioxide, sukari madara (lactose), polyethylene glycol 4000, talc ana amfani dasu don waɗannan dalilai.

Ariescor sune allunan da suke samuwa a cikin allurai biyu - 10 ko 20 mg. Su ne zagaye, matte, an rufe shi da farin harsashi.

Aikin magunguna

Allunan abinci na Ovenkor an tsara su azaman prodrugs. Tsarin simvastatin yana da nau'i na zobe na lactone. Saboda haka, ba zai iya hulɗa da masu hanawar cholesterol ba. Amma a cikin hanta, yana ba da kanta ga canjin sunadarai. Tsarin aiki na simvastatin yana da kama sosai da na enzyme HMG-CoA reductase, wanda ya wajaba don haɓakar cholesterol. Saboda wannan dabarar, ya ɗauki matsayinsa cikin halayen sunadarai. Wani sashin kwayar kwayar halitta a wannan yanayin ya tsoma baki tare da ƙirƙirar ƙwayoyin cholesterol. Saboda wane ne, ana rage ƙwayoyin kwayoyin halitta.
Jiki yana amsa raguwar cholesterol ta hanyar ƙara yawan ayyukan masu karɓa na LDL, yana haɓaka rushewar su. LDL kitse ne mai “mara kyau” wanda ke taimakawa ga samuwar saka hannun jari a jikin bangon jijiyoyin jini. Saboda haka, shan Ovenkor yana rage haɗarin haɓakar atherosclerosis.

Kamar kowane mutum-mutumi, Ovenkor baya tasiri a cikin ayyukan enzymes wanda ke rushewar kitse (lipases), kira, da rushewar kitse mai kyauta. Saboda haka, raguwa a cikin matakin tsaka tsaka mai tsaka tsaki (triglycerides, TG) shine mafi yawan lokuta sakamakon kunnawa masu karɓar ƙwayar hanta. Suna taɓarɓarewar ƙwayoyin lipoproteins ɗimbin yawa, 30% ya ƙunshi TG.

An tabbatar da cewa amfani da miyagun ƙwayoyi Ariescor:

  • da gaske ya shafi jihar na ciki Layer na jini (endothelium), ganuwar jini,
  • normalizes jini ya kwarara
  • yana da kaddarorin antioxidant
  • rage hadarin cututtukan zuciya.

Dangane da umarnin don amfani da Ovenkor, an lura da haɓaka ci gaba cikin endothelium bayan wata daya na maganin.

Ana amfani da miyagun ƙwayoyi ta hanyar sha mai kyau. Matsakaicin mafi girman hankali a cikin jini yana faruwa awanni 4 bayan shigar da kwamfutar hannu Ovenkor a cikin jiki. Ana lura da ingantattun canje-canje na farko cikin matakan cholesterol bayan makonni 2.

Mafi yawan simvastatin tare da bile suna shiga cikin hanji, daga inda aka kewaya da feces. Wani nau'in ƙwayar magani mara amfani shine kodan ya bice.

Hanyar aikace-aikacen, sashi

Jiyya tare da Ovencor yana buƙatar abinci kafin fara magungunan, kazalika a duk lokacin da ake yin magani.

An zaɓi kashi na miyagun ƙwayoyi daban-daban. Ana bada shawara don fara amfani da karamin sashi, tare da ƙara ƙaruwa. Mun rubuta a sama cewa ana samun mafi girman rage yawan cholesterol kwanaki 28 bayan fara maganin. Abin da ya sa ƙarin sauƙaƙan matakan sauyawa ba sa ma'ana.

Thewarin da aka ba da shawarar farko na Ovenkor shine 5-20 mg / rana, kuma mafi girman shine 40 MG / rana. Ga marasa lafiya da ke ɗaukar immunosuppressants, yin amfani da simvastatin an iyakance shi zuwa kashi 5 na rana / rana. A cikin gazawar ƙirar ƙima, koyarwar tana ba da shawarar farawa tare da kashi 5-10 mg / rana.

Imiarfafawa da kuma bioavailability na miyagun ƙwayoyi ga jikin ba su da alaƙa da abinci. Kuna iya ɗaukar shi kafin / bayan / lokacin abinci, kar ku manta da shan ruwa mai yawa. Babban mahimmancin buƙata: Allunan ya kamata a bugu sau ɗaya a rana da yamma.

Haɗa kai

Tare da gudanar da aikin warfarin tare da wasu magungunan anticoagulants tare da Avencor, ana inganta tasirin ƙarshen. Hakanan yana haifar da yawan guba ga hanta, magunguna waɗanda ke cutar da wannan ƙwayar.

Saboda haɗarin rhabdomyolysis, ba a yarda da amfani da miyagun ƙwayoyi ba:

  • tare da keto, itraconazole, babban allurai na Vitamin PP,
  • mutane suna shan magungunan immunosuppressive.

Likitocin sun rubuta kararrakin cutar rhabdomyolysis bayan kashi daya na simvastatin tare da sildenafil. Ana amfani da wannan magani don gyara lalatawar jijiyoyin.

Farashin Ovenkor yana da tasiri sosai game da batun siyarwa. A cikin birane daban-daban da kuma magunguna na Rasha, ya bambanta sosai. Don haka ɗayan kunshin 10 MG na iya farashin daga 275 rubles, da kuma 20 mg sashi - daga 419 zuwa 578 rubles.

A cikin kowane kantin magani zaka iya samun analogues na Ovenkor - kwayoyi tare da kayan aiki guda, amma daga masana'anta daban. Simvastatin wani bangare ne na: Simvagesal, Zokor, Simvor, Simvakard, Simvastatin, Simvastol, Simgal, Simlo, Vasilip. Baya ga farashin, waɗannan magungunan sun banbanta a gwargwado mai araha. Misali, akwai magunguna tare da 5 da 40 MG na kayan aiki. Wannan ya dace idan likita ya ba da irin wannan adadin.

Abubuwan da marubutan aikin suka shirya
bisa ga tsarin edita na shafin.

Masu canza marasa ƙarfi don Ovenkor

Analog mai rahusa daga 313 rubles.

Simvastatin magani ne na Rasha mai matukar fa'ida tare da sashi mai aiki iri ɗaya a cikin abun da ke ciki, amma a mafi ƙarancin sashi na 10 a kowace kwamfutar hannu. An tsara shi don lura da hypercholesterolemia na farko da na hyperlipidemia na farko. Ana iya samun cikakken jerin alamomi a cikin umarnin.

Simvastol (Allunan) Rating: 4 Top

Analog ne mai rahusa daga 265 rubles.

Simvastol shine kwatankwacin samarwa da Romaniyanci. Akwai shi a cikin kwali na kwali na 14 da allunan. Abunda yake aiki iri ɗaya ne a nan, saboda haka umarnin amfani kawai ya ƙunshi ƙananan bambance-bambance. Kafin fara magani, muna bada shawarar sosai ga likita.

Analog mai rahusa daga 173 rubles.

Wani madadin kasashen waje don Ovenkor, wanda kuma ya zama mafi fa'ida fiye da "asali", kodayake ba ta bambanta da shi. Contraindicated a cikin ciki, lactation da kuma a cikin yara. Duk jerin abubuwan contraindications ana iya samu a cikin umarnin.

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