Amoxiclav foda don dakatarwar 400 MG 57 MG

Amoxiclav ® shine mai hade da amoxicillin - maganin semisynthetic penicillin tare da aikin antibacterial mai yawa da kuma clavulanic acid - mai hana maye gurbin β-lactamases. Clavulanic acid ya samar da wani hadadden tsarin aiki tare da wannan enzymes kuma yana tabbatar da juriya da amoxicillin zuwa sakamakon tasirin β-lactamases da kwayoyin halitta suka haifar.

Clavulanic acid, mai kama da tsari don maganin rigakafin beta-lactam, yana da rauni mai hana ƙwayoyin cuta.

Amoxiclav ® yana da rawar gani iri-iri na aikin hana ƙwayoyin cuta.

Aiki da Xicasassun ƙwayar cuta mai narkewa, ciki har da β-lactamase na haifar da damuwa, gami da aerobic gram-tabbatacce ƙwayoyin cuta: Hyptococcus pneumoniae, Streptococcus pyogenes, budurwai na Streptococcus, Streptococcus bovis, Staphylococcus aureus (banda maɗaurin tsayayya methicillin), epidermidis mai maganin staphylococcus (banda don methicillin-resistant strains), Staphylococcus saprophyocppus,. aerobic gram-korau kwayoyin: Bordetella pertussis, Brucella spp., Campylobacter jejuni, Escherichia coli, Gardnerella vaginalis, Haemophilus mura, Haemophilus ducreyi, Klebsiella spp., Moraxella catarrhalis, Pippis neisseria gonorrhoeae Somppella meppida meisseria Vibrio cholerae, Yersinia enterocolitica, Helicobacter pylori, Eikenella corrodens, kwayoyin cutar anaerobic gram-tabbatacce: Kawain spp., Kawarskumar spp., Clostridium spp., Actinomyces israelii, Fusobacterium spp., Prevotella spp., gram-korau anaerobes: Bacteroides spp.

Pharmacokinetics

Babban ma'aunin magunguna na amoxicillin da clavulanic acid sun yi kama.

Abubuwan haɗin duka suna haɗuwa sosai bayan shan miyagun ƙwayoyi a ciki, cin abinci baya shafar ƙimar sha. C_max a cikin jini jini ana samun sa'a 1 bayan gudanarwa. C dabi'u_max gyara don maganin amoxicillin (gwargwadon sashi) 3-12 μg / ml, don acid acid - kusan 2 μg / ml.

Dukansu abubuwan haɗin suna haɗuwa da ingantaccen girma na rarrabewa a cikin ruwan jiki da kyallen takarda (huhu, kunne na tsakiya, pleural da peritoneal ruwaye, mahaifa, ovaries, da sauransu). Har ila yau, Amoxicillin ya shiga cikin hanji mai narkewa, hanta, guntuwar prostate, ƙwanƙarin palatine, ƙwayar tsoka, ƙonewar mafitsara, ɓoyewar sinuses, ciwan, hanji.

Amoxicillin da clavulanic acid ba su shiga cikin BBB ba tare da meninges wanda ba a bayyana shi ba.

Amoxicillin da clavulanic acid sun haɗu da katangar ƙwarya kuma a cikin abubuwan da aka gano suna keɓance a cikin madara. Amfani da ƙwayar cuta mai narkewa da kuma clavulanic acid ana ɗaukar su ta hanyar ƙananan ɗauri don sunadaran plasma.

Amoxicillin yana cikin metabolized, clavulanic acid a fili yana fuskantar matsanancin metabolism.

Amoxicillin an cire shi da kodan kusan ba a canza shi ta hanyar tubular ɓoyewa da kuma ruɗar murfin ƙasa. Clavulanic acid an raba shi ta hanyar dunƙule ƙasa, wani ɓangare na metabolites. Ana iya fitar da ƙananan adadi ta hanji da huhu. T_1/2 amoxicillin da acid clavulanic shine 1-1.5 hours

Pharmacokinetics a cikin lokuta na musamman na asibiti

A cikin gazawar rashin aiki na T_1/2 yana ƙaruwa zuwa 7.5 hours don amoxicillin kuma har zuwa 4.5 hours don clavulanic acid. Dukkanin abubuwan guda biyu ana cire su ta hanyar cututtukan hemodialysis da ƙananan adadi ta hanyar jijiyoyin bugun jini.

Cututtukan da ke haifar da cututtukan ƙwayoyin cuta mai lalacewa:

- cututtukan cututtuka na jijiyoyin jiki na sama da gabobin ENT (gami da cututtukan cututtukan ƙwayar cuta da cututtukan ƙwayar cuta, matsanancin ƙwaƙwalwa na otitis media, pharyngeal abscess, tonsillitis, pharyngitis),

- cututtukan cututtukan ƙananan ƙwayar cuta na ciki (ciki har da babban mashako tare da superinfection na kwayan cuta, mashako na huhu, huhu),

Kwayar cututtukan hanji

- cututtukan fata da fata, laushi, gami da dabbobi da ciwan mutum,

- cututtuka na kasusuwa da nama mai haɗuwa,

- cututtukan biliary fili (cholecystitis, cholangitis),

Contraindications

- Rashin hankali ga kowane ɓangare na maganin,

- Hypersensitivity a cikin tarihi zuwa maganin penicillins, cephalosporins da sauran maganin rigakafin beta-lactam,

- tarihin alamomin cholestatic jaundice da / ko sauran aikin hanta mai rauni wanda ke haifar da tsarin amoxicillin / clavulanic acid,

- Kwayar cutar mononucleosis da cutar kuturta.

Tare da taka tsantsan ya kamata a yi amfani da miyagun ƙwayoyi tare da tarihin cutar ta pseudomembranous colitis, tare da gazawar hanta, matsanancin ƙwayar na koda, da lokacin lactation.

Side effects

Abubuwan da ke haifar da sakamako a cikin mafi yawan lokuta masu laushi ne da kan lokaci.

Daga tsarin narkewa: asarar ci, tashin zuciya, amai, gudawa, da wuya na ciki, wahala hanta aiki, ƙarancin aiki na enzymes hanta (ALT ko AST), a cikin lokuta da aka ware - cholestatic jaundice, hepatitis, pseudomembranous colitis.

Allergic halayen: pruritus, urticaria, erythematous rash, da wuya - Multiforme exudative erythema, angioedema, anaphylactic shock, rashin lafiyar fitsari, a lokuta mafi ƙaranci - cututtukan da suka haifar da rashin lafiya, cututtukan Stevens-Johnson, matsanancin haɓakar exanthematous pustulosis.

Daga tsarin cutar haemopoietic da lymphatic system: da wuya - ana iya jujjuya leukopenia (gami da neutropenia), thrombocytopenia, da wuya - hemolytic anemia, zazzagewa ta karuwa a lokacin prothrombin (idan aka haɗu da anticoagulants), eosinophilia, pancytopenia.

Daga tsarin juyayi: rashin jin tsoro, ciwon kai, da wuya - jinkiri (na iya faruwa a cikin marasa lafiya da ke fama da rauni game da aiki yayin shan kwayoyi), tashin hankali, damuwa, rashin bacci.

Daga tsarin urinary: da wuya sosai - interstitial nephritis, crystalluria.

Sauran: da wuya - cin gaban superinfection (gami da candidiasis).

Yawan abin sama da ya kamata

Babu wani rahoton mutuwa ko cutar da ke haifar da barazanar rayuwa saboda yawan shan kwayoyi.

Kwayar cutar a mafi yawancin lokuta, rikice-rikice na ƙwayar gastrointestinal (ciwon ciki, zawo, amai), tashin hankali, rashin bacci, tsananin ƙima ma yana yiwuwa;

Jiyya: ya kamata mai haƙuri ya kasance a ƙarƙashin kulawa na likita, maganin kwantar da hankali. Game da gwamnatin kwanan nan na miyagun ƙwayoyi (kasa da awanni 4), ya wajaba a wanke ciki kuma a rubuta maganin gawayi don rage shaye-shayen maganin. Ana cire maganin amoxicillin / potassium clavunate ta hanyar hemodialysis.

Umarni na musamman

Tare da hanyar kulawa, ya kamata a sa ido kan ayyukan jini, hanta da kodan.

A cikin marasa lafiya da ke fama da rauni na aiki na kyanda, ana buƙatar cikakkiyar gyaran allurar rigakafi ko karuwa a tsakanin tazara tsakanin dosing.

Don rage haɗarin mummunan sakamako daga cututtukan gastrointestinal, ya kamata a sha miyagun ƙwayoyi tare da abinci.

Gwaje-gwaje na dakin gwaje-gwaje: babban adadin amoxicillin yana ba da amsa ta gaskiya ga ƙin fitsari lokacin amfani da renon ɗin Benedict ko mafita. Ana bada shawarar halayen enzymatic tare da glucosidase.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Babu bayanai game da mummunan tasirin Amoxiclav a cikin allurai da aka bada shawarar akan iya tuki mota ko aiki da injin.

Hulɗa da ƙwayoyi

Tare da amfani da magani na lokaci guda Amoxiclav ® tare da antacids, glucosamine, laxatives, aminoglycosides, sha yana rage gudu, tare da ascorbic acid - yana ƙaruwa.

Diuretics, allopurinol, phenylbutazone, NSAIDs da wasu kwayoyi waɗanda ke toshe ɓarin tubular ƙara yawan haɗarin amoxicillin (clavulanic acid an ware shi musamman ta hanyar lalata ƙasa).

Ta amfani da Amoxiclav ® a lokaci guda yana ƙara yawan guba na methotrexate.

Tare da yin amfani da Amoxiclav tare da allopurinol lokaci guda, haɗarin exanthema yana ƙaruwa.

Ya kamata a guji gudanar da ayyukan haɗin kai tare da disulfiram.

A wasu halaye, shan miyagun ƙwayoyi na iya tsawan lokacin prothrombin, a wannan batun, yakamata a yi taka tsantsan yayin da ake rubuta magungunan anticoagulants da kuma miyagun ƙwayoyi Amoxiclav ®.

Haɗin amoxicillin tare da rifampicin antagonistic ne (akwai rauni na juna game da tasirin ƙwarin ƙwayar cuta).

Kada a yi amfani da Amoxiclav sim lokaci guda tare da kwayoyin rigakafin ƙwayoyin cuta (macrolides, tetracyclines), sulfonamides saboda raguwar yiwuwar tasirin Amoxiclav.

Probenecid yana rage haɓakar amoxicillin, yana ƙaruwa da ƙwaƙwalwar magani.

Magungunan rigakafi suna rage tasirin maganin hana haifuwa.

Hanyar aikace-aikace

Yawan maganin yau da kullun na dakatarwar 125 mg + 31.25 mg / 5 ml da 250 mg + 62.5 mg / 5 ml (don sauƙaƙe kyakkyawan dace na dakatarwa na 125 mg + 31.25 mg / 5 ml da 250 mg + 62.5 mg / 5 ml na dakatarwa a cikin kowane kunshin, ana saka cokali mai ƙima tare da damar 5 ml ko kuma wanda aka sauke digiri na pipette).

Jariri da yara har zuwa watanni 3 nada 30 MG / kg (amoxicillin) / rana, an kasu kashi biyu (kowane awanni 12), yara sama da watanni 3 - daga 20 MG (amoxicillin) / kg / rana a cututtukam zuwa matsakaici mai rauni har zuwa 40 mg / kg (bisa ga amoxicillin) / rana a mummunan kamuwa da cuta da cututtukan hanji An kasu kashi uku (kowane awanni 8).

Saka shawarar allurai na dakatarwa ya danganta da nauyin jikin yaro da tsananin cutar.

Girman jiki (kg)	Shekaru (kimanin)	Huhu / matsakaitan kamuwa da cuta		Cututtukan kamuwa da cuta
Girman jiki (kg)	Shekaru (kimanin)	125 mg + 31.25 mg / 5 ml	250 MG + 62.5 mg / 5 ml	125 mg + 31.25 mg / 5 ml	250 MG + 62.5 mg / 5 ml
5-10	3-12 watanni	3 × 2.5 ml (1 /₂ l.)	3 × 1.25 ml (1 /₄ l.)	3 × 3.75 ml (3 /₄ l.)	3 × 2 ml (1 /₄- 1 /₂ l.)
10-12	1-2 shekaru	3 × 3.75 ml (3 /₄ l.)	3 × 2 ml (1 /₄- 1 /₂ l.)	3 × 6.25 ml (1 1 /₄ l.)	3 × 3 ml (1 /₂- 3 /₄ l.)
12-15	Shekaru 2-4	3 × 5 ml (1 l.)	3 × 2.5 ml (1 /₂ l).	3 × 7.5 ml (1 1 /₂ l.)	3 × 3.75 ml (3 /₄ l.)
15-20	Shekara 4-6	3 × 6.25 ml (1 1 /₄ l.)	3 × 3 ml (1 /₂- 3 /₄ l.)	3 × 9.5 ml (1 3 /₄-2 l.)	3 × 5 ml (1 l.)
20-30	Shekaru 6-10	3 × 8.75 ml (1 3 /₄ l.)	3 × 4.5 ml (3 /₄-1 l.)	-	3 × 7 ml (1 1 /₄-1 1 /₂ l.)
30-40	Shekaru 10-12	-	3 × 6.5 ml (1 1 /₄ l.)	-	3 × 9.5 ml (1 3 /₄-2 l.)
≥ 40	Years shekara 12	An tsara Amoxiclav ® a cikin allunan

Allurai na yau da kullun dakatarwa 400 MG + 57 mg / 5 ml ana lissafta ta 1 kg na nauyin jiki dangane da tsananin kamuwa da cuta kuma sune 25-45 mg / kg nauyin jiki / rana (cikin sharuddan amoxicillin), an kasu kashi biyu.

Don sauƙaƙe allurar da ta dace, an sanya fitowar 400 mg + 57 mg / 5 ml a cikin kowane kunshin na pipette, an yi karatun digiri a lokaci guda, a cikin 1, 2, 3, 4, 5 ml da 4 sassa daidai.

Sanin shawarar dakatarwa ya dogara da nauyin jikin ɗan yaro da tsananin kamuwa da cuta.

Girman jiki (kg)	Shekaru (kimanin)	Cututtukan kamuwa da cuta	Cutar matsakaici
5-10	3-12 watanni	2 × 2.5 ml (1 /₂ pipettes)	2 × 1.25 ml (1 /₄ pipettes)
10-15	1-2 shekaru	2 × 3.75 ml (3 /₄ pipettes)	2 × 2.5 ml (1 /₂ pipettes)
15-20	Shekaru 2-4	2 × 5 ml (1 pipette)	2 × 3.75 ml (3 /₄ pipettes)
20-30	Shekara 4-6	2 × 7.5 ml (1 1 /₂ pipettes)	2 × 5 ml (1 pipette)
30-40	Shekaru 6-10	2 × 10 ml (2 pipettes)	2 × 6.5 ml (1 1 /₄ pipettes)

Ana yin lissafin ainihin allurai na yau da kullun gwargwadon nauyin jikin ɗan, ba wai shekarun sa ba.

Matsakaicin adadin maganin amoxicillin shine na manya 6 g don yara - 45 MG / kg nauyin jiki.

Matsakaicin adadin yau da kullun na clavulanic acid (a cikin nau'i na gishiri na potassium) shine na manya 600 MG na yara - 10 mg / kg nauyin jiki.

A marasa lafiya tare da mummunan gazawar koda (CC kasa da 10 ml / min) yakamata a rage kashi sosai ko kuma tazara tsakanin allurai biyu yakamata a kara (tare da cutar kansa har zuwa awanni 48 ko sama da haka).

Aikin magani shine kwanaki 5-14. Dogon likitan ne ya tantance tsawon lokacin da ake bi da shi. Jiyya kada ta wuce kwanaki 14 ba tare da binciken likita na biyu ba.

Dokoki don shirye-shiryen dakatarwa

Foda don shirye-shiryen dakatar da 125 mg + 31.25 mg / 5 ml: girgiza kwalban da karfi, ƙara ruwa na ruwa 86 (a mark) a allurai biyu, kowane lokaci girgiza sosai har sai foda ya narke gaba ɗaya.

Foda don shiri na dakatar da 250 mg + 62.5 mg / 5 ml: girgiza kwalban da karfi, ƙara ruwa na ruwa 85 (har alamar) a allurai biyu, kowane lokaci girgiza sosai har sai foda ya narke gaba ɗaya.

Foda don shirye-shiryen dakatarwar 400 MG + 57 mg / 5 ml: da karfi girgiza kwalban, ƙara ruwa a cikin adadin da aka nuna akan alamar kuma aka nuna a teburin (a alamar) a allurai biyu, kowane lokaci girgiza sosai har sai foda ya narke gaba ɗaya.

Girman bidiyo	Yawan ruwan da ake buƙata
35 ml	29.5 ml
50 ml	42 ml
70 ml	59 ml
140 ml	118 ml

Kafin amfani, murfin ya kamata ya girgiza sosai.

Amoxiclav: abun da ke ciki da alamomi don amfani

Amoxiclav shine maganin rigakafin kwayoyin cuta wanda za'a iya ɗauka don magance cututtukan da yawa, farawa daga mashako kuma yana ƙare da matsalolin koda. Abubuwan da ke aiki da magungunan sune:

Abubuwan taimako na Amoxiclav sun hada da:

Na citrate
citric acid
xanthan gum,
Na benzoate,
silloon silicon dioxide,
carmellose Na,
Na saccharin,
dandano (ceri, strawberry, lemun tsami),
mannitol.

An tsara maganin rigakafi kawai idan sanadin cutar cuta ce mai cutarwa. An wajabta Amoxiclav ga yara da manya don kamuwa da cuta na hanji da na baya da kuma gabobin ENT. Irin waɗannan hanyoyin kumburi sun haɗa da:

kwayar cutar tarin fuka (tonsillitis),
m ko na kullum sinusitis,
m otitis kafofin watsa labarai
pharyngitis
cutar huhu,
ciwon kumburin ciki,
sinusitis
mashako
ciwon huhu

Yin amfani da maganin rigakafi yana da kyau a yanayin saukan:

Hanyar fitarwa: dakatarwa da Allunan

Masana'antar masana'antar ba da magunguna tana ba wa mabukaci nau'i biyu na sakin maganin ƙurar ƙwayar cuta. Na farko shine kwayoyin hana daukar ciki. Ya fi dacewa da manya. Babban fa'idar wannan nau'in ita ce allunan sun dace don amfani ko'ina, lura da yanayin shiga. Ana samun su cikin allurai na 250 da 500 na amoxicillin da 125 mg na clavulanic acid. A cikin bolaji - allunan 15 ko 20.

Na biyu nau'i na saki shine foda wanda aka shirya dakatarwar. Zai fi kyau yaro ya sami amoxiclav a cikin wannan tsari, musamman ga waɗanda har yanzu ba su san yadda za su tauna ko hadiye allunan ba.

Tebur da ke ƙasa yana nuna sashi wanda aka samar da ƙwayar ƙwaƙwalwar ƙwayar ƙwayar ƙwayoyi na Amoxiclav ga yara:

Adadin duka a cikin 5 ml na dakatarwa, mg	Kashi na amoxicillin, mg	Kashi na acid na clavulanic, mg
125	125	31,25
250	250	62,5
400	400	57

Foda da dakatarwa sune farin fari ko launin shuɗi. Ana samun samfurin a cikin kwantena na gilashi mai duhu tare da ƙaramin 100 ml. A cikin kwalban 25 grams na foda. Akwatin an sanye shi da cokali mai aunawa ko pipette. Yadda za a shirya dakatarwa, zaku iya karanta umarnin da aka haɗe kuma ku kalli bidiyon don labarin tare da matakan matakan mataki-mataki-mataki.

Yaya za a lissafa sashi na miyagun ƙwayoyi?

Don cimma sakamako mai kyau na hanzari daga shan ƙwayar rigakafi da rage ƙarancin tasirin sakamako, kuna buƙatar ƙayyade adadin ƙwayar da daidai kuma tsarma da kyau kuma ku bai wa yaron syrup ko allunan su sha.

Don yin lissafin daidai sabis na Amoxiclav, yakamata a yi la’akari da maki masu zuwa:

shekarun yarinyar
nauyin karamin haƙuri
takamaiman cuta
tsananin tsananin cutar.

Ga yara daga watanni biyar zuwa shekara goma tare da matsakaicin matsakaicin matakan cutar, ya isa ya tsarke foda tare da sashi na 125 MG. Idan ciwon makogwaro, ciwon huhu ko wata hanya yana da wahala, to an wajabta magani tare da wani abu mai aiki da ƙwayoyin cuta a cikin adadin 250 ko 400 MG.

A rataya - don yara yan shekaru goma sha biyu

Lokacin amfani da foda, mataki na farko shine shirya dakatarwa. Don yin wannan, zuba foda da ruwa a cikin kwalbar ga haɗarin da ke tattare da saman gilashin ta. Ya kamata a dafa ruwa a sanyaya. Bayan cakuda dole ne a girgiza su, saboda haka yana gauraye.Za'a iya adanar dakatarwar da aka shirya don ba ta wuce mako guda a cikin firiji.

Yin amfani da cokali mai aunawa ko sirinji, auna ƙimar syrup. Yaya yawan abin da ake buƙata don ba da syrup ga jariri har zuwa shekara ɗaya ko yaro ya fi girma za'a iya samun shi a cikin umarnin don amfani. Ya ƙunshi Tables kuma ya bayyana yadda ake amfani da su don ƙididdige yawan adadin magungunan. Lokacin da yake rubuta ƙwayar rigakafi, likita dole ne ya nuna sashi don wani yanayi, la'akari da shekaru da cuta, sannan kuma ya ce tsawon kwanakin da ya kamata ku ɗauki ƙwayar ƙwayar ƙwayar cuta.

Idan yaro bai cika watanni 3 da haihuwa ba, to, maganin yau da kullun shine kashi 30 a kowace kilo 1 na nauyin jikin. Ana ɗaukar magani kowane awa 12. Bayan watanni 3, kashi shine 20 MG kowace kilogram, amma ana ba da magani a kowane awa 8. Wannan yana tare da hanya mai sauƙi ko matsakaici na cutar. A cikin lokuta masu rauni, yana ƙaruwa zuwa 40 MG / kg tare da lokaci ɗaya.

Don saukakawa, waɗannan masu zuwa ne matakin dakatarwar Amoxiclav na shekaru daban-daban a cikin lemon:

Shekarun yara	Sashi, teaspoons	Yawan liyafar da rana
3-12 watanni	1/2	3
1-7 shekara	1	3
Shekaru 7-14	2	3

A cikin allunan - don manyan yara

Tsarin kwamfutar hannu na maganin antibacterial miyagun ƙwayoyi an tsara shi don manya da yara sama da shekaru 12-14. Tabletaya daga cikin kwamfutar hannu ya ƙunshi 375 MG na kayan aiki mai aiki. Ana shan su sau uku a rana, kwamfutar hannu ɗaya.

Yawan yana bambanta dangane da yanayin. Tare da angina, ana bai wa yara kwamfutar hannu tare da tazara na awanni 8, tare da wata cuta - kowane awa 12. A cikin lokuta masu tsauri, likitan halartar na iya haɓaka guda ɗaya don cimma sakamako mai sauri.

Yaya za a ba da kwayoyi ga yara masu shekaru daban-daban?

Ba tare da la'akari da shekarun masu haƙuri ba, akwai ƙa'idodi kan yadda za a ɗauki Amoxiclav:

Yarda da abinci. Idan kun sha maganin tare da abinci, wannan yana rage haɗarin sakamako masu illa daga hanji.
Shiri na dakatarwa kafin amfani.
Kulawa da yanayin jariri. Yana da mahimmanci a lura da duk canje-canje a cikin yanayin da halayen ƙaramin haƙuri, duka tabbatacce kuma mara kyau. Tare da bayyanar mara kyau, ya kamata ka daina shan miyagun ƙwayoyi ka je neman shawara tare da gwani.
Kada ku katse hanya. Ana gyara sakamako bayan an gama maganin.
Kula da ranar karewa. Yana shekara 2. An adana ƙarewar da aka gama a cikin firiji don babu fiye da kwanaki 7.
Bi umarnin allurai.
Gudanarwa akan yanayin kodan, hanta da tsarin wurare dabam dabam.

Tare da m zuwa matsakaici mai rauni

Yawan maganin da aka wajabta ta fannoni da yawa yana ƙayyade ba shekarun mai haƙuri ba, amma nauyin jikinsa, saboda duk yara sun bambanta, nauyinsu a daidai lokacin yana da bambanci sosai. Koyaya, tsananin matsalar cutar tana taka muhimmiyar rawa a cikin ayyukan rigakafi.

Amma ga mai laushi da matsakaitan sifofin cutar, to, ƙa'idar tsari tana aiki. An wajabta dakatarwar 125 ko 250 ml sau uku a rana. Wajibi ne a sha maganin kashe kwayoyin cuta na kwanaki 5-7. Gaskiya ne, ya rage ga likita ne ya yanke wannan shawarar. Kada ku wuce da tsawon lokaci, mitar ko girman yau da kullun. Yana da haɗari kuma yana barazanar rikitarwa. Idan tasirin bai gudana tare da tsarin zaɓaɓɓen magani ba, to maganin ƙwaƙwalwar ƙwayar cuta bai dace da yaƙar takamaiman cutar ba.

A cikin kamuwa da cuta mai tsanani

Dangane da mummunan yanayin aikin cututtukan, tsarin yana canzawa. Don magani, dakatarwa tare da ƙwayar cuta mai ƙwayar cuta na 400 MG. Hakanan an wajabta su sha sau uku a rana. Farfesa yana ƙarƙashin kulawar likita. Tare da yardarsa ne kawai za'a iya yin gyare-gyare. Misali, yawan yau da kullun yana ƙaruwa da kashi ɗaya bisa uku. Hanyar magani na iya wuce sati biyu. A cikin wannan, yanayin mai haƙuri yana taka muhimmiyar rawa.

Wadanne cutarwa da rikitarwa ke yiwuwa?

Magungunan ƙwayoyin cuta sune kayan aiki masu tasiri waɗanda ke ba da sakamako mai sauri. Akwai mummunan gefen - jerin kyawawan halayen halayen m. Tasirin mummunar ƙwayar ƙwayar ƙwayar cuta na Amoxiclav mafi yawan lokuta yana rinjayar aikin ƙwayar ƙwayar jijiyoyin jiki kuma yana bayyana kanta a matsayin rashin lafiyan ƙwayar cuta. A magana ta farko, yaro yana da:

talaucin abinci
amai
tashin zuciya
zawo
dysbiosis.

Sau da yawa ba sau da yawa, shan Amoxiclav yana haɗuwa tare da jin zafi a cikin ciki, colitis, gazawar hanta, hepatitis, jaundice. Dangane da rashin lafiyan, yana bayyana kansa kamar:

Baya ga alamu mara kyau da ke sama, sauran tsarin jiki kuma na iya zama mummunan tasirin: cututtukan zuciya, ƙwayar cutar hanji, urinary da na tsakiya na juyayi. Yaron ya bayyana:

thrombocytopenia
leukopenia
anemia
eosinophilia
kwankwantin
babbar murya
cutuka nephritis,
tsananin farin ciki
ciwon kai
rashin ƙarfi
tashin hankalin bacci
wuce kima damuwa
katsewa.

Suna

Sunan Rasha na miyagun ƙwayoyi shine Amoxiclav, Latin - Amoksiklav.

Lambar miyagun ƙwayoyi a cikin ATX (anatomical-therapeutic-chemical) rarrabuwa shine J01CR02.

Amoxiclav shine magungunan kashe kwayoyin cuta daga rukuni masu kariya na penicillins.

Saki siffofin da abun da ke ciki

Ana sayar da Amoxiclav 400 MG a foda foda, wanda aka diluted don samun dakatarwa. Foda yana da fari ko launin rawaya. Abunda ke aiki (amoxicillin) yana cikin nau'in trihydrate. Adadin sinadarin potassium beta-lactamase inhibitor shine 57 MG. Tare tare da wakili mai hana ƙwayoyin cuta, abubuwan da ke cikin foda sun haɗa da gum, sodium benzoate, citric acid, mannitol, dandano, silicon dioxide da sauran abubuwan haɗin. Ana cakuda foda a cikin kwalabe (tare da pipette) da fakiti.

Alamu don amfani

An wajabta Amoxiclav 400 don halayen masu zuwa:

Cututtukan gabobin ENT da jijiyoyin bugun jini na sama (otitis media, lalacewar sinuses, ƙonewar hanji, kumburin ƙwayoyin hanji, maƙogwaron da maƙogwaron).
Cutar kumburin huhu da kuma hanji.
Cututtukan cututtukan cututtukan ƙwayoyin cuta na jijiyoyin jiki (urethritis, cystitis, kumburi da kodan, endometritis, lalata lalacewar mahaifa, vulvovaginitis).
Cututtukan kasusuwa (osteomyelitis) da nama mai haɗuwa.
Kumburi daga cikin gallbladder da bile ducts.
Dabbobin dabbobi.
Fata na fata (pyoderma).
Cututtukan Odontogenic akan asalin lalacewar hakori.

An wajabta Amoxiclav 400 don cututtuka na gabobin ENT da jijiya na sama.
An wajabta maganin rigakafi a cikin lura da cututtukan da ke kama da jijiyoyin ƙwayoyin cuta na ƙwayoyin cuta (urethritis, cystitis, kumburi da kodan, endometritis, lalacewar kayan aikin mahaifa, vulvovaginitis).
An wajabta cututtukan ƙashi da tsoka mai haɗari don lura da Amoxiclav 400.
Tare da kumburi na hanji da na bile, ana wajabta wannan maganin.
An wajabta Amoxiclav don cizon dabbobi.
An wajabta magungunan don cututtukan fata (pyoderma).
Tare da kumburi da huhun hanji da bronchi, an wajabta wannan maganin.

Ana amfani da maganin sosai a cikin maganin hana haihuwa da ilimin ilimin mahaifa.

Yadda ake ɗaukar Amoxiclav 400

Lokacin da ake tsara wakilin magunguna don ƙaddamarwa, ana la'akari da halayen shekarun marasa lafiya da yanayin su.

Maganin maganin manya shine 25-45 mg / kg. Yawan maganin yana iya kaiwa 2,085 MG. Kunshin ya ƙunshi cokali mai aunawa tare da ƙaramin 5 ml ko pipette mai digiri. Matsakaicin adadin (na amoxicillin) shine g 6. Ana shan maganin sau biyu a rana tare da abinci.

Sashi don yara

Ga yara daga watanni 3 zuwa shekara masu nauyin 5-10 kilogiram, an sanya magani a cikin sashi na ¼ ko ½ pipette, ya danganta da tsananin cutar sau 2 a rana. Ga yara 'yan shekaru 1-2 da yin nauyi 10-15 kilogiram, maganin da aka bada shawarar daga from zuwa ¾ pipettes. An tsara yara a cikin shekaru 2-3 tare da nauyin 15-20 kg daga ¾ zuwa 1 naúrar. Sau 2 a rana. Babban alamar ƙididdigar ƙira ba shekaru bane, amma nauyin yaro.

Babban mahimmancin ƙididdigar ƙididdigar ƙididdigar ƙwayar cuta ba tsufa ba ne, amma nauyin yaron.

Gastrointestinal fili

Lokacin ɗaukar maganin, alamun lalacewar tsarin narkewa (tashin zuciya, rashin ci, mai saurin kwance sako, jin zafi a ciki, amai) mai yiwuwa ne. A lokuta masu tsauri, akwai:

Jaundice Yana faruwa saboda tururuwar bile.
Ciwon mara.
Cututturar ƙwayar cuta mai cuta.
Levelsara matakan enzymes na hanta (ALT da AST).

Ofaya daga cikin tasirin sakamako na shan maganin na iya zama ci gaban hepatitis.
Cutar cuta ta pseudomembranous shine ɗayan ɓangarorin abubuwan da ke haifar da amfani da Amoxiclav.
A cikin lokuta masu tsanani, akwai karuwa a cikin matakan hanta enzymes.
Lokacin ɗaukar ƙwayar rigakafi a cikin lokuta masu wahala, ana lura da cutar taƙasa.
Lokacin shan maganin, alamun lalacewar gabobin narkewa (tashin zuciya, rashin ci) zai yiwu.

Daga tsarin urinary

Wasu masu haƙuri suna haɓakar nephritis (kumburi da kodan). Babban adadin salts na iya fitowa a cikin fitsari.

Lokacin amfani da Amoxiclav, halayen rashin lafiyan yana faruwa (redness of skin, papular rash of the nooca urticaria, itching, angioedema, dermatitis, shock da Stevens-Johnson syndrome).

Lokacin amfani da Amoxiclav, halayen rashin lafiyan na faruwa (jan fata, fitsari da ke kama da irin cututtukan urtikaria, itching, da sauransu).

Yin hulɗa tare da wasu kwayoyi

Yin amfani da Amoxiclav 400 a lokaci guda tare da antacids, chondroprotectors na tushen glucosamine, aminoglycosides, maganin hana haihuwa, methotrexate, allopurinol, disulfiram, anticoagulants, macrolides, maganin rigakafi daga rukunin tetracycline da sulfonamides ba da shawarar ba. Yana rage taro na Amoxiclav Probenecid.

Promoara yawan taro na amoxiclav a cikin jini yana ƙaruwa ta:

Analogs na Amoxiclav 400 sune Amoxiclav Quiktab da Augmentin (ana iya shirya maganin allura daga gare ta).

Misalin Amoxiclav 400 shine Augmentin.

Ranar karewa

Ana adana foda tsawon shekaru 2 daga ranar da aka shirya shi. Dakatarwar da aka gama ya dace har sati guda idan an ajiye shi a cikin firiji a zazzabi + 2 ... + 8ºC a cikin kwalban rufe.

Nazarin likitan game da miyagun ƙwayoyi na Amoxiclav: alamomi, gudanarwa, sakamako masu illa, umarnin analogues na Amoxiclav don amfani da allunan Amoxiclav Amoxiclav | analogues

Nazarin Amoxiclav 400

Nazarin kwararru da mutanen da suka yi amfani da samfurin magunguna galibi tabbatacce ne.

Yuri, dan shekara 47, Kostroma: “Mafi yawaita a kan bayar da maganin ne na marasa lafiya da ke fama da cututtukan kumburi da gabobin mace. Jiyya ta fi dacewa da bin ka'idodin tsabtar mace. ”

Valery, mai shekara 32, Vorkuta: “Amoxiclav yana taimakawa sosai tare da kamuwa da cuta na gabobin ENT, gami da tsakiyar kunne. Magungunan ba su da tsada kuma da wuya yana ba da sakamako masu illa. "

Alena, mai shekara 28, a Moscow: “Yaron da ke da shekaru 4 da sannu ya kamu da cutar sankara a hanunsa. Bi da su tare da Amoxiclav 400 a foda foda. Babban magani. ”

Tsari sashi:

foda don dakatarwa don gudanarwa na baka.

Kowane 5 ml na dakatarwar 400 mg + 57 mg / 5 ml ya ƙunshi:
abubuwa masu aiki: amoxicillin (a cikin nau'i na trihydrate) dangane da abu mai aiki - 400 MG, clavulanic acid (a cikin nau'i na giyar potassium) a cikin yanayin abu mai aiki - 57 MG, magabata: citric acid (anhydrous) - 2.694 mg, sodium citrate (anhydrous) - 8.335 mg, microcrystalline cellulose da sodium carmellose - 28.1 mg, xanthan gum - 10.0 mg, colloidal silicon dioxide - 16.667 mg, silicon dioxide - 0.217 g, dandano na daji ceri - 4,000 MG, lemun tsami lemon - 4,000 MG, saccharinate sodium - 5,500 MG, mannitol har zuwa 1250 MG.
Kowane 5 ml na dakatarwar 250 mg + 62.5 mg / 5 ml ya ƙunshi:
abubuwa masu aiki: amoxicillin (a cikin nau'i na trihydrate) dangane da abu mai aiki - 250 MG, clavulanic acid (a cikin nau'i na gishirin potassium) a cikin yanayin abu mai aiki - 62.5 mg, magabata: citric acid (anhydrous) - 2.167 mg, sodium citrate (anhydrous) - 8.335 mg, sodium benzoate - 2.085 mg, microcrystalline cellulose da sodium carmellose - 28.1 mg, xanthan gum - 10.0 MG, colloidal silicon dioxide - 16.667 mg, silicon dioxide - 0.217 g, dandano ckin daji - 4,000 MG, saccharinate sodium - 5,500 MG, mannitol har zuwa 1250 MG.
Kowane 5 ml na dakatarwa na 125 mg + 31.25 mg / 5 ml ya ƙunshi:
abubuwa masu aiki: amoxicillin (a cikin nau'i na trihydrate) dangane da abu mai aiki - 125 mg, clavulanic acid (a cikin nau'i na giyar potassium) a cikin yanayin abu mai aiki - 31.25 mg, magabata: citric acid (anhydrous) - 2.167 mg, sodium citrate (anhydrous) - 8.335 mg, sodium benzoate - 2.085 mg, microcrystalline cellulose da sodium carmellose - 28.1 mg, xanthan gum - 10.0 MG, colloidal silicon dioxide - 16.667 mg, silicon dioxide - 0.217 g, dandano strawberry - 15,000 MG, saccharinate sodium - 5,500 MG, mannitol har zuwa 1250 MG.

Bayanin: foda: daga fari zuwa fari mai launin shuɗi.
Dakatarwa kusan fararen fata zuwa rawaya masu kama da juna.

Kayan magunguna

Pharmacodynamics
Hanyar aikin
Amoxicillin shine kwaro-kwalayen kwalayen kwalayen kwayoyi masu motsa jiki tare da aiki da yawa da kwayoyin cuta na gram-tabbatacce kuma na gram-korau. A lokaci guda, amoxicillin yana da saukin kamuwa da lalacewa ta hanyar beta-lactamases, sabili da haka bakan aikin amoxicillin baya wuce zuwa microorganisms waɗanda ke samar da wannan enzyme.
Clavulanic acid, wani sinadarin beta-lactamase inhibitor wanda ya shafi penicillins, yana da ikon hana nau'ikan beta-lactamases da yawa da aka samo a cikin maganin penicillin da cephalosporin mai jure kwayoyin. Clavulanic acid yana da isasshen inganci a kan maganin beta-lactamases, wanda yake mafi yawan lokuta yana jure ƙwayar ƙwayar cuta, kuma baya da tasiri a kan nau'in chromosome beta-lactamases, wanda acid ɗin ba su hana shi ba.
Kasancewar acid na clavulanic a cikin shirye-shiryen yana kare amoxicillin daga lalacewa ta hanyar enzymes - beta-lactamases, wanda ke ba da damar fadada ƙwayoyin ƙwayoyin cuta na amoxicillin.
Mai zuwa aiki ne na haɗakar amoxicillin tare da clavulanic acid a cikin vitro.

Gram-tabbatacce aerobes: Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Nocardia asteroides, Streptococcus pyogenes 1,2, Streptococcus agalactiae 1,2, sauran beta-hemolytic steptococci 1,2, Staphylococcus aureus (methicillin-m) 1, Staphylolo coagulase-korau staphylococci (kula da methicillin).
Gram-korau jirgin sama: Bordetella pertussis, Haemophilus mura 1, Helicobacter pylori, Moraxella catarrhalis 1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.
Sauran: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.
Anaerobes na Gram-tabbatacce: nau'in halittar Clostridium, Peptococcus niger, Peptostrepiococcus magnus, Peptostreptococcus micros, nau'in halittar Peptostreptococcus.
Gram-korau anaerobes: Bacteroides fragilis, nau'in halittar Bacteroides, nau'in halittar Capnocytophaga, Eikenella corrodens, Fusobacterium nucleatum, nau'in halittar Fusobacterium na halittar Porphyromonas, nau'in halittar halittar Prevotella.

Kwayar cuta wacce ta samu juriya tana iya yiwuwa
zuwa haɗuwa da amoxicillin tare da acid acid clavulanic

Aerobes na Gram-korau: Escherichia coli1, Klebsiella oxytoca, Klebsiella pneumoniae, nau'in halittar Klebsiella, Proteus mirabilis, Proteus vulgaris, nau'in halittar garkuwa da garkuwar jiki, nau'in halittar dan adam Salmonella, nau'in halittar Shigella. Kwayar cutar kwayar cutar kwaro kwaro 1,2, kungiyar kwayar cutar kwayar cutar kwayar cutar kwayar cuta.
Gram-tabbatacce aerobes: nau'in kwayar halittar Corynebacterium, Enterosocus faecium.

Ta halitta Juriya kwayoyin cuta
zuwa haɗuwa da amoxicillin tare da acid acid clavulanic

Gram-korau jirgin sama: nau'in halittar halittar Acinetobacter, Citrobacter freundii, nau'in halittar Enterobacter, Hafnia alvei, Legionella pneumophila, Morganella morganii, nau'in halittar genenenenen, jinsin halittar Pseudomonas, nau'in halittar genus Serratia, Stenotrophomonas maltophilia.
Sauran: Chlamydia pneumoniae, Chlamydia psittaci, nau'in halittar Chlamydia, Coxiella burnetii, nau'in kwayoyin Mycoplasma.
1 na waɗannan ƙwayoyin cuta, ingantaccen aikin asibiti na haɗarin amoxicillin tare da clavulanic acid an nuna shi a cikin karatun asibiti.
Abubuwa 2 na waɗannan nau'ikan ƙwayoyin cuta ba sa samar da beta-lactamases.Mahimmanci tare da monotherapy na amoxicillin yana ba da shawarar irin wannan hankalin game da haɗarin amoxicillin tare da clavulanic acid.

Pharmacokinetics
Damuwa
Abubuwan da ke cikin ƙwayar suna aiki da sauri kuma suna karɓe su daga ƙwayar gastrointestinal (GIT) bayan sarrafa bakin. Rashin abubuwa masu aiki shine mafi kyau duka game da amfani da miyagun ƙwayoyi tare da abinci.
Belowasan da ke tattare da sigogin magunguna na amoxicillin da clavulanic acid bayan gudanarwa a kashi 45 MG / 6.4 mg / kg, ya kasu kashi biyu, ta marasa lafiya ƙarƙashin shekarun 12.

Matsakaicin darajar magunguna

Сmax - matsakaicin maida hankali ga plasma,

Tmax - lokaci domin kaiwa ga yawan maida hankalin plasma,
Kungiyar AUC ita ce yankin da ke kan layi "lokacin taro",
T1 / 2 - rabin rayuwa.

Tsarin rayuwa
Kimanin kashi 10-25% na kashin farko na amoxicillin an cire shi ta hanyar ƙwayar mara amfani (maganin penicilloic acid). Acid na Clavulanic a jikin dan Adam yana gudanar da aiki mai karfi sosai ta hanyar samarda 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid da kuma 1-amino-4-hydroxy-butan-2-daya kuma kodan ya raba shi, ta hanyar narkewa, har da iska mai narkewa, a cikin nau'in carbon dioxide.
Rarraba
Kamar yadda yake cikin haɗuwar ƙwayar ƙwayar ƙwayar cuta ta amoxicillin da clavulanic acid, ana samun yawan abubuwan kwantar da hankali na amoxicillin da clavulanic acid a cikin kyallen iri daban-daban da ruwa mai shiga jiki (a cikin gallbladder, tsokoki na ciki, fata, adipose da ƙwayoyin tsoka, jikewar jiki da ruwa mai fitarwa, zazzaɓi, da fitowar jini) .
Amoxicillin da acid na clavulanic suna da rauni mai ƙarfi na ɗaure wa sunadaran plasma. Bincike ya nuna cewa kusan kashi 25% na adadin clavulanic acid da kashi 18% na amoxicillin a cikin jini yana da dangantaka da garkuwar jini na jini.
Ofimar rarraba shine kusan 0.3-0.4 L / kg don amoxicillin da kimanin 0.2 L / kg don acid acid na clavulanic.
Amoxicillin da acid na clavulanic basa ƙetare shinge na jini-kwakwalwa a cikin meninges wanda ba a rufe shi ba. Amoxicillin (kamar yawancin penicillins) an keɓe shi a cikin madara.
Hakanan ana iya samun halaye na clavulanic acid a cikin madara. Bayan ban da yiwuwar hankali, zazzabin cizon sauro, da kuma candidiasis na mucosa na baki, babu wasu mummunan tasirin amoxicillin da acid na clavulanic akan lafiyar jarirai masu shayarwa.
Karatuttukan dabbobi na dabbobi sun nuna cewa amoxicillin da clavulanic acid sun ƙetare shinge na jini. Koyaya, ba'a gano lahani ga tayin ba.
Kiwo
Amoxicillin ne aka raba shi da ƙodan, yayin da acid ɗin clavulanic ke cikin duka hanyoyin aikin koda da na gaba. Bayan an gudanar da sarrafa baki ɗaya na 875 mg / 125 mg ko 500 mg / 125 mg, kimanin 60-70% na amoxicillin da 40-65% na clavulanic acid ana cire su ta hannun kodan a cikin awanni 6 na farko.
Matsakaicin rabin-rayuwa (T1 / 2) na amoxicillin / clavulanic acid shine kimanin awa 1; matsakaicin yardawar kusan shine 25 l / h a cikin marasa lafiya. A cikin binciken daban-daban, an gano cewa haɓakar ƙwayar ƙwayar ƙwayar cuta ta hanta a cikin sa'o'i 24 yana kusan kashi 50-85%, clavulanic acid - 27-60%.
Mafi yawan adadin acid ɗin clavulanic an keɓance shi a cikin awanni 2 na farko bayan gudanarwa.
Magungunan ƙwayoyin cuta na amoxicillin / clavulanic acid basu dogara da jinsi na haƙuri ba.
Marasa lafiya tare da nakasa aiki na renal
Adadin jimlar amoxicillin / clavulanic acid yana raguwa a gwargwadon raguwa a aikin aikin koda. Rage yarda ya zama mafi ƙira ga amoxicillin fiye da na clavulanic acid, saboda Mafi yawan amoxicillin suna dauke da kodan. Allurai na miyagun ƙwayoyi don gazawar renal ya kamata a zaɓi yin la'akari da undesirability na tarawa na amoxicillin yayin da yake riƙe da matakin al'ada na clavulanic acid.
Marasa lafiya tare da nakasa aikin hanta
A cikin marasa lafiya da ke fama da rauni na hanta, ana amfani da miyagun ƙwayoyi tare da taka tsantsan. Wajibi ne a kula da aikin hanta kodayaushe.
Dukkanin abubuwan guda biyu ana cire su ta hanyar cututtukan hemodialysis da adadi kaɗan ta hanyar ƙirar bugun jini.

Yi amfani da lokacin daukar ciki da lokacin shayarwa

Karatun dabbobi bai bayyana bayanai game da hatsarorin shan miyagun ƙwayoyi ba yayin daukar ciki da tasirin sa ga cigaban tayi.
Studyaya daga cikin binciken da aka yi a cikin mata masu tsufa na ƙwayoyin cuta sun gano cewa maganin prophylactic tare da amoxicillin / clavulanic acid na iya haɗuwa da haɓakar haɗarin kamuwa da cuta mai ƙosasshen ƙwayoyin cuta a cikin jarirai.
A lokacin daukar ciki da lactation, ana amfani da maganin ne kawai idan amfanin da aka yi niyya ga uwa ya fi girman hadarin da tayi ga jaririn da jariri.
Amoxicillin da clavulanic acid a cikin adadi kaɗan sun shiga cikin madara, sabili da haka, shan miyagun ƙwayoyi yayin shayarwa ya kamata a ci gaba kawai idan akwai alamun bayyanannu.
A cikin jarirai masu karbar nono, haɓakar jiyya, zawo, candidiasis na mucous membranes na bakin ciki yana yiwuwa. A irin waɗannan halaye, ya kamata a daina shayar da jariri.

Side sakamako

Dangane da Hukumar Lafiya ta Duniya (WHO), ana rarrabewa da mummunan sakamako gwargwadon yawan ci gaban su kamar haka: sosai akai (> 1/10), akai-akai (> 1/100, 1/1000, 1/10000, daga gabobin jini na ciki da jijiyoyin jini tsarin
da wuya: leukopenia mai iya juyawa (hade da sinadarin neutropenia), thrombocytopenia,
da wuya eosinophilia, thrombocytosis, farfadowa agranulocytosis, karuwa a lokacin zubar jini da kuma sakewa game da cutar prothrombin, anaemia, gami da sake dawo da cutar haemolytic.
Daga tsarin rigakafi
da wuya angioedema, halayen anaphylactic, rashin lafiyar jijiyoyin bugun jini, wata cuta mai kama da cutar sankara.
Daga tsarin juyayi
a koyaushe: farin ciki, ciwon kai,
da wuya rashin bacci, tashin hankali, damuwa, canjin hali, jujjuyawar yanayin aiki, rashiwa, raɗaɗi na iya faruwa a cikin marasa lafiya da ke fama da matsalar aiki na ƙarancin ƙasa, da kuma a cikin waɗanda ke karɓar ƙwayoyi masu yawa.
Daga cikin hanji
galibi: asarar ci, tashin zuciya, amai, zawo,
Ana samun yawan cutar tashin zuciya a lokacin da ake yawan allura mai yawa. Idan an tabbatar da cin zarafin ƙwayar gastrointestinal, za'a iya kawar da su idan kun sha maganin a farkon abincin.
a koyaushe: narkewa cikin fushi
da wuya kwayoyin cuta masu hadewar kwayoyi masu guba ta hanyar shan maganin rigakafi (gami da cututtukan mahaifa da cutar basur), baki “mai gashi”, baki, stomatitis.
A cikin yara, ba za a taɓa gano ƙasan farfaɗar rufin farfaɗar hakorin hakori ba. Kulawar baki yana taimakawa hana fashewar hakorin hakori.
A ɓangaren fata
a koyaushe: fata fata, itching, urticaria,
da wuya: erythema multiforme exudative,
da wuya Stevens-Johnson syndrome, mai guba necrolysis mai guba, ƙwaƙwalwar ƙwayar cuta mai banƙyama, ƙwararrun ƙwayar cuta mai narkewar ƙwayar cuta mai narkewar cuta.
Daga tsarin urinary
da wuya crystalluria, interstitial nephritis, hematuria.
A wani ɓangaren hanta da ƙwayar biliary
a koyaushe: haɓaka ayyukan alanine aminotransferase (ALT) da / ko aspartate aminotransferase (AST), (ana lura da wannan sabon abu a cikin marasa lafiya da ke karɓar maganin ƙwayoyin cuta na beta-lactam, amma ba a san mahimmancin asibitin ba).
An lura da munanan al'amuran daga hanta musamman a cikin maza da tsofaffi marasa lafiya kuma ana iya haɗa su da magani na dogon lokaci. Ba a taɓa ganin irin waɗannan lamuran a cikin yara ba.
Alamun da alamomin da aka lissafa yawanci suna faruwa ne a lokacin ko kuma kai tsaye bayan ƙarshen maganin, duk da haka a wasu halayen da ba za su iya bayyana ba tsawon makonni da yawa bayan kammala maganin. Mummunan abubuwa yawanci ana jujjuya su.
Mummunan al'amuran daga hanta na iya zama mai wahala, a cikin mawuyacin halaye akwai rahotannin sakamako mai ƙarewa. A kusan dukkan halayen, waɗannan mutane ne da ke ɗauke da cutar ta cuta ko waɗanda ke karɓar magungunan hepatotoxic lokaci guda.
da wuya karuwa a cikin alkaline phosphatase, karuwa a cikin bilirubin, hepatitis, cholestatic jaundice (an lura da maganin kwantar da hankali tare da sauran maganin penicillins da cephalosporins).
Sauran
galibi: candidiasis na fata da ƙwayoyin mucous,
ba a sani ba mita: ci gaba da m microorganisms.

Fom ɗin saki

Foda don maganin dakatarwa
Don sashi na 125 mg + 31.25 mg / 5 ml da 250 mg + 62.5 mg / 5 ml:
Fakitin farko: 25 g na foda (100 ml na dakatarwa) a cikin gilashin gilashi mai duhu tare da alamar zobe (100 ml). An rufe kwalban tare da dunƙule dunƙule wanda aka yi da polyethylene mai ɗimbin yawa tare da zoben sarrafawa kuma tare da hatimin conical a cikin hula ko murfin ƙarfe mai ƙwanƙwasa tare da zoben sarrafawa, a cikin hula akwai kwallan da aka yi da ƙarancin yawan polyethylene.
Sakandare na biyu:
Bottleaya daga cikin kwalba ɗaya tare da cokali na sashi tare da alamomin shekara a cikin ƙwayar 2.5 ml da 5 ml ("2.5 SS" da "5 SS"), mafi girman alamar cika 6 ml ("6 SS") akan alƙawarin cokali da umarnin don amfani da lafiya a cikin kwali.
Bottleaya daga cikin kwalba ɗaya tare da ɗalibin digiri na ɗalibi da umarnin don amfani da likita a cikin kwali.
Don sashi na 400 mg + 57 mg / 5 ml:
Farashin farko: 8.75 g (35 ml na dakatarwa), 12.50 g (50 ml na dakatarwa), 17.50 g (70 ml na dakatarwa) ko 35.0 g (140 ml na dakatarwa) na foda a cikin kwalban duhu gilashin tare da dunƙule dunƙule wanda aka yi da polyethylene mai ɗimbin yawa tare da zoben sarrafawa da tare da hatimin hatpes a cikin hat.
17.50 g (70 ml na dakatarwa) a cikin gilashin gilashi mai duhu tare da alamar zobe (70 ml) tare da dunƙule dunƙule wanda aka yi da polyethylene mai girma tare da zobe mai sarrafawa tare da hatimin conical a cikin hula.
Sakandare na biyu:
Bottleaya daga cikin kwalba ɗaya tare da ɗalibin digiri na ɗalibi da umarnin don amfani da likita a cikin kwali.